MARS2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description methionyl-tRNA synthetase 2, mitochondrial|This gene produces a mitochondrial methionyl-tRNA synthetase protein that is encoded by the nuclear genome and imported to the mitochondrion. This protein likely functions as a monomer and is predicted to localize to the mitochondrial matrix. Mutations in this gene are associated with the autosomal recessive neurodegenerative disease spastic ataxia-3 (SPAX3). [provided by RefSeq, Apr 2014] (NCBI Entrez Gene Database, 92935)
External Link https://ncbi.nlm.nih.gov/gene/92935
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Genes

500 genes differentially expressed following the MARS2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0234587
GNAS GNAS complex locus 0.0176994
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.015368
OXA1L oxidase (cytochrome c) assembly 1-like 0.0142024
KDM5D lysine (K)-specific demethylase 5D 0.0138899
KRT6A keratin 6A, type II 0.013555
SLPI secretory leukocyte peptidase inhibitor 0.0134783
LTF lactotransferrin 0.0122327
S100A7 S100 calcium binding protein A7 0.0103677
COG7 component of oligomeric golgi complex 7 0.0100545
WDR7 WD repeat domain 7 0.0099379
MLF1 myeloid leukemia factor 1 0.00988913
KRT5 keratin 5, type II 0.00975008
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.00965572
S100A2 S100 calcium binding protein A2 0.00920885
KRT13 keratin 13, type I 0.00920793
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.00895752
KRT14 keratin 14, type I 0.00886105
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00874008
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00873589
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00851224
COCH cochlin 0.0084732
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.00839633
SFTPB surfactant protein B 0.00836266
FOXG1 forkhead box G1 0.00817808
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00815442
CNPY3 canopy FGF signaling regulator 3 0.00809852
SPRR1B small proline-rich protein 1B 0.00809268
PCLAF PCNA clamp associated factor 0.00807019
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00795268
GPM6B glycoprotein M6B 0.00794493
WFDC2 WAP four-disulfide core domain 2 0.00791558
RGCC regulator of cell cycle 0.00787972
KRT6B keratin 6B, type II 0.0078297
PI3 peptidase inhibitor 3, skin-derived 0.00778867
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.0077535
TMEM45A transmembrane protein 45A 0.00764189
COG5 component of oligomeric golgi complex 5 0.0076319
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.00763154
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 0.00761026
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00760565
SFTPD surfactant protein D 0.0075989
SFTPA2 surfactant protein A2 0.00755834
MAP2K6 mitogen-activated protein kinase kinase 6 0.00755403
SYNGR3 synaptogyrin 3 0.0075341
TUBB2A tubulin, beta 2A class IIa 0.0075018
S100A9 S100 calcium binding protein A9 0.00749455
UFC1 ubiquitin-fold modifier conjugating enzyme 1 0.0074893
FABP7 fatty acid binding protein 7, brain 0.00747299
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00742551
LAMP3 lysosomal-associated membrane protein 3 0.00742439
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 0.00736931
FCGBP Fc fragment of IgG binding protein 0.00729627
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00725703
MSRB2 methionine sulfoxide reductase B2 0.00725592
LRRN3 leucine rich repeat neuronal 3 0.00709796
SOX11 SRY (sex determining region Y)-box 11 0.00708645
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00705496
PMP2 peripheral myelin protein 2 0.00704154
ITM2A integral membrane protein 2A 0.00702736
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00702468
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00700881
DAD1 defender against cell death 1 0.00692896
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.00692094
KRT16 keratin 16, type I 0.00691721
CHEK2 checkpoint kinase 2 0.00688837
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.00680567
PFDN5 prefoldin subunit 5 0.00675866
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.00671395
MMP10 matrix metallopeptidase 10 0.00671367
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00666636
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00661633
FOLR1 folate receptor 1 (adult) 0.00655556
MAL mal, T-cell differentiation protein 0.0065409
LGALS13 lectin, galactoside-binding, soluble, 13 0.00651931
KRT17 keratin 17, type I 0.00646087
HAUS4 HAUS augmin-like complex, subunit 4 0.00645307
LTA4H leukotriene A4 hydrolase 0.0064384
ARMCX6 armadillo repeat containing, X-linked 6 0.00641961
DCHS1 dachsous cadherin-related 1 0.0064147
CST7 cystatin F (leukocystatin) 0.00639255
LAPTM5 lysosomal protein transmembrane 5 0.00632963
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.00631522
A2M alpha-2-macroglobulin 0.00629643
ESD esterase D 0.00628677
PMEPA1 prostate transmembrane protein, androgen induced 1 0.00627244
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.00627013
USP9Y ubiquitin specific peptidase 9, Y-linked 0.00626571
EGFL6 EGF-like-domain, multiple 6 0.00625155
S100B S100 calcium binding protein B 0.00622194
AUTS2 autism susceptibility candidate 2 0.00620888
PRKCQ protein kinase C, theta 0.00619359
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 0.00618721
LAMC2 laminin, gamma 2 0.00618472
LY6D lymphocyte antigen 6 complex, locus D 0.00613762
ATP5F1C ATP synthase F1 subunit gamma 0.00610879
MPV17 MpV17 mitochondrial inner membrane protein 0.00610236
MGP matrix Gla protein 0.00609362
NPEPL1 aminopeptidase-like 1 0.00607832
PUF60 poly-U binding splicing factor 60KDa 0.00607239
ZIC1 Zic family member 1 0.00604912
SELENOT selenoprotein T 0.00604644
RHOA ras homolog family member A 0.00604414
MEG3 maternally expressed 3 (non-protein coding) 0.00601415
MUC4 mucin 4, cell surface associated 0.00598309
ELAVL1 ELAV like RNA binding protein 1 0.00597995
S100A14 S100 calcium binding protein A14 0.00597928
CETN2 centrin, EF-hand protein, 2 0.00596869
PTN pleiotrophin 0.00593702
MAGED1 melanoma antigen family D1 0.00593555
GSTA4 glutathione S-transferase alpha 4 0.00592734
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00591939
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 0.00591608
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.00590935
ADORA2B adenosine A2b receptor 0.00588967
TMEM231 transmembrane protein 231 0.00587633
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00587405
MSLN mesothelin 0.00586075
TRIM16 tripartite motif containing 16 0.00585478
TXNL1 thioredoxin-like 1 0.00585227
RNF167 ring finger protein 167 0.00584747
ABITRAM actin binding transcription modulator 0.00584739
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.00584589
EDN3 endothelin 3 0.00584504
SELENOW selenoprotein W 0.00584436
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 0.00580652
GMPR2 guanosine monophosphate reductase 2 0.00578886
ATP5F1A ATP synthase F1 subunit alpha 0.00577826
ARHGAP15 Rho GTPase activating protein 15 0.00577389
KIFAP3 kinesin-associated protein 3 0.0057719
RNF125 ring finger protein 125, E3 ubiquitin protein ligase 0.00576503
NCAN neurocan 0.00576362
PRAME preferentially expressed antigen in melanoma 0.00575728
OLFML2A olfactomedin-like 2A 0.0057502
RPL35 ribosomal protein L35 0.0057294
BCHE butyrylcholinesterase 0.00571507
COMMD10 COMM domain containing 10 0.00570247
OTULINL OTU deubiquitinase with linear linkage specificity like 0.00568947
FAM171A1 family with sequence similarity 171, member A1 0.00566149
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.00565972
FAM162A family with sequence similarity 162, member A 0.00561746
GLOD4 glyoxalase domain containing 4 0.00561408
RPL26L1 ribosomal protein L26-like 1 0.00560678
CHI3L2 chitinase 3-like 2 0.00556693
CLCA1 chloride channel accessory 1 0.00556123
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00552162
RPS5 ribosomal protein S5 0.00551407
TCAF1 TRPM8 channel-associated factor 1 0.00550818
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 0.00550387
ARHGAP44 Rho GTPase activating protein 44 0.00549079
TMEM47 transmembrane protein 47 0.00548868
CYB5A cytochrome b5 type A (microsomal) 0.00548779
CAPZB capping protein (actin filament) muscle Z-line, beta 0.00548453
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00547371
CD59 CD59 molecule, complement regulatory protein 0.00545439
RPL12 ribosomal protein L12 0.00544727
GMFG glia maturation factor, gamma 0.00543927
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.00543478
ANG angiogenin, ribonuclease, RNase A family, 5 0.00542935
TAGLN2 transgelin 2 0.00541185
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 0.00540991
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.0054044
LYRM4 LYR motif containing 4 0.00539341
RPL14 ribosomal protein L14 0.0053672
AQP4 aquaporin 4 0.00536141
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.00534796
SPRR3 small proline-rich protein 3 0.00534494
TSPAN6 tetraspanin 6 0.0053316
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene) 0.00531404
EEF1B2 eukaryotic translation elongation factor 1 beta 2 0.0053084
SSR4 signal sequence receptor, delta 0.00530406
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.00530338
SMAD2 SMAD family member 2 0.00529275
MRPS33 mitochondrial ribosomal protein S33 0.00526728
PITX1 paired-like homeodomain 1 0.00525922
CRYL1 crystallin, lambda 1 0.00524408
EIF4A3 eukaryotic translation initiation factor 4A3 0.00523791
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 0.00523536
PDE4D phosphodiesterase 4D, cAMP-specific 0.00523358
YME1L1 YME1-like 1 ATPase 0.00521668
PRTN3 proteinase 3 0.0051879
COL4A5 collagen, type IV, alpha 5 0.00517998
IGBP1 immunoglobulin (CD79A) binding protein 1 0.00517178
AAMDC adipogenesis associated, Mth938 domain containing 0.00516866
COMMD3 COMM domain containing 3 0.00514693
NOP53 NOP53 ribosome biogenesis factor 0.00514144
CD1E CD1e molecule 0.00511846
SPRR1A small proline-rich protein 1A 0.00511063
EIF3F eukaryotic translation initiation factor 3, subunit F 0.00509918
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 0.00508436
ERGIC3 ERGIC and golgi 3 0.00508382
REEP5 receptor accessory protein 5 0.00508269
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.00507523
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 0.00507172
PRPF4 pre-mRNA processing factor 4 0.00506673
MAGT1 magnesium transporter 1 0.00505451
MED22 mediator complex subunit 22 0.00505309
TMEM230 transmembrane protein 230 0.00504799
BMERB1 bMERB domain containing 1 0.00504496
SOD3 superoxide dismutase 3, extracellular 0.00504476
CREB5 cAMP responsive element binding protein 5 0.0050293
PON3 paraoxonase 3 0.00502748
CFDP1 craniofacial development protein 1 0.00502132
NSL1 NSL1, MIS12 kinetochore complex component 0.00501795
SKP1 S-phase kinase-associated protein 1 0.00501482
RPL36 ribosomal protein L36 0.00498531
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) 0.00498428
APOC1 apolipoprotein C-I 0.00498361
NEBL nebulette 0.00498217
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00495885
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00492804
GPN1 GPN-loop GTPase 1 0.00492554
C6ORF48 chromosome 6 open reading frame 48 0.00490194
CSTA cystatin A (stefin A) 0.00489802
SLA Src-like-adaptor 0.00489411
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.00489399
SEPP1 selenoprotein P, plasma, 1 0.0048882
CLCA2 chloride channel accessory 2 0.00488549
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00488139
IFITM3 interferon induced transmembrane protein 3 0.0048746
MMP8 matrix metallopeptidase 8 0.00483474
NCOA4 nuclear receptor coactivator 4 0.00481859
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 0.00481558
PENK proenkephalin 0.0048122
PLCE1 phospholipase C, epsilon 1 0.00481064
CSRNP3 cysteine-serine-rich nuclear protein 3 0.00480936
KIF1A kinesin family member 1A 0.00479907
THNSL2 threonine synthase-like 2 (S. cerevisiae) 0.0047989
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.00479004
TSPAN1 tetraspanin 1 0.00478953
RPL35A ribosomal protein L35a 0.00477877
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.00477029
TRAPPC2L trafficking protein particle complex 2-like 0.00476184
GUCY1B3 guanylate cyclase 1, soluble, beta 3 0.00474746
SEPTIN9 septin 9 0.00474395
MDH1 malate dehydrogenase 1, NAD (soluble) 0.00474279
EMP1 epithelial membrane protein 1 0.00474054
BPIFA1 BPI fold containing family A, member 1 0.00473277
AHCYL2 adenosylhomocysteinase-like 2 0.00471358
MAP7 microtubule-associated protein 7 0.00470718
IFT52 intraflagellar transport 52 0.00470636
MPZL2 myelin protein zero-like 2 0.00470567
CCND2 cyclin D2 0.0046948
HOXB13 homeobox B13 0.00468725
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.0046835
TXNL4A thioredoxin-like 4A 0.00468125
IL13RA2 interleukin 13 receptor, alpha 2 0.00467916
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.00466757
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 0.00466218
CYBRD1 cytochrome b reductase 1 0.00464964

decreased expression

Symbol Name Standardized Value
SLC38A1 solute carrier family 38, member 1 -0.0144103
XIC X chromosome inactivation center -0.0139848
PLIN2 perilipin 2 -0.0128901
AMIGO2 adhesion molecule with Ig-like domain 2 -0.0120805
PTK2 protein tyrosine kinase 2 -0.0117806
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.0115592
RHOBTB3 Rho-related BTB domain containing 3 -0.0115029
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0111126
PLXNB2 plexin B2 -0.0109633
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -0.0109467
G0S2 G0/G1 switch 2 -0.0109195
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.0107788
CXCL14 chemokine (C-X-C motif) ligand 14 -0.0107131
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.0104866
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.0104746
MT1E metallothionein 1E -0.0103674
MT1H metallothionein 1H -0.0102597
MT1X metallothionein 1X -0.010219
CDCA4 cell division cycle associated 4 -0.0101541
FBP1 fructose-1,6-bisphosphatase 1 -0.0100908
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.0100872
KANK1 KN motif and ankyrin repeat domains 1 -0.010003
TCTA T-cell leukemia translocation altered -0.00992569
METTL7A methyltransferase like 7A -0.00984355
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00974656
GAS1 growth arrest-specific 1 -0.00972159
GMPR guanosine monophosphate reductase -0.00959176
KRT18 keratin 18, type I -0.00952296
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.00935968
HOXC6 homeobox C6 -0.00934462
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00930518
CLU clusterin -0.00929823
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00927592
TOB1 transducer of ERBB2, 1 -0.0091846
LYZ lysozyme -0.00915077
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00908221
CCNG2 cyclin G2 -0.00901898
SDC4 syndecan 4 -0.00901196
SCGB2A2 secretoglobin, family 2A, member 2 -0.00891597
MTCL1 microtubule crosslinking factor 1 -0.00891331
ALB albumin -0.00881407
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00863996
FABP4 fatty acid binding protein 4, adipocyte -0.00862732
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00861049
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00852852
EIF1AX eukaryotic translation initiation factor 1A, X-linked -0.00850155
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00848619
MT1G metallothionein 1G -0.00847513
NOTCH2 notch 2 -0.00843429
ARHGAP29 Rho GTPase activating protein 29 -0.00836516
PLS3 plastin 3 -0.00830992
MGLL monoglyceride lipase -0.00829141
CPE carboxypeptidase E -0.00824569
MT1HL1 metallothionein 1H-like 1 -0.00823191
ZBTB18 zinc finger and BTB domain containing 18 -0.00823029
DACT1 dishevelled-binding antagonist of beta-catenin 1 -0.00816174
HHEX hematopoietically expressed homeobox -0.00806251
ADIRF adipogenesis regulatory factor -0.00802962
SGK1 serum/glucocorticoid regulated kinase 1 -0.00791043
MB myoglobin -0.0079095
CPB1 carboxypeptidase B1 (tissue) -0.00779914
THBS4 thrombospondin 4 -0.00779305
QPCT glutaminyl-peptide cyclotransferase -0.00767578
TNIP1 TNFAIP3 interacting protein 1 -0.00765334
BICC1 BicC family RNA binding protein 1 -0.00763579
COQ8A coenzyme Q8A -0.0076355
CA2 carbonic anhydrase II -0.00760962
PID1 phosphotyrosine interaction domain containing 1 -0.00760019
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00756758
ANPEP alanyl (membrane) aminopeptidase -0.00755396
MT2A metallothionein 2A -0.00753993
FST follistatin -0.00743986
GDF15 growth differentiation factor 15 -0.00741879
EPCAM epithelial cell adhesion molecule -0.00738976
CTSA cathepsin A -0.0073374
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00731853
COMP cartilage oligomeric matrix protein -0.00730247
FADS3 fatty acid desaturase 3 -0.00729652
TRAPPC2 trafficking protein particle complex 2 -0.00726946
RRAGA Ras-related GTP binding A -0.00724137
FGFR1 fibroblast growth factor receptor 1 -0.00720811
OSBPL10 oxysterol binding protein-like 10 -0.00717269
TOX3 TOX high mobility group box family member 3 -0.00714032
PLAAT3 phospholipase A and acyltransferase 3 -0.00713007
BCL2L1 BCL2-like 1 -0.0070785
CTBP2 C-terminal binding protein 2 -0.00706407
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00705499
TGFB1 transforming growth factor, beta 1 -0.00704841
CD36 CD36 molecule (thrombospondin receptor) -0.00698952
MARCKS myristoylated alanine-rich protein kinase C substrate -0.00698178
MDFIC MyoD family inhibitor domain containing -0.00696902
TNS3 tensin 3 -0.00695793
SFRP1 secreted frizzled-related protein 1 -0.00695595
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00694801
TPBG trophoblast glycoprotein -0.00694091
NPY1R neuropeptide Y receptor Y1 -0.00693462
COL14A1 collagen, type XIV, alpha 1 -0.00689154
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked -0.00687894
CAV1 caveolin 1, caveolae protein, 22kDa -0.00687138
PSAT1 phosphoserine aminotransferase 1 -0.00679613
PLIN1 perilipin 1 -0.0067717
CEMIP2 cell migration inducing hyaluronidase 2 -0.00676179
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.0067368
IL1R1 interleukin 1 receptor, type I -0.00672895
HIP1R huntingtin interacting protein 1 related -0.006715
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00669637
SMC1A structural maintenance of chromosomes 1A -0.00668764
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.0066798
TXLNA taxilin alpha -0.00667527
F13A1 coagulation factor XIII, A1 polypeptide -0.00666242
EPB41L4B erythrocyte membrane protein band 4.1 like 4B -0.00665125
BLNK B-cell linker -0.00662008
CRIP2 cysteine-rich protein 2 -0.00659316
CSRP2 cysteine and glycine-rich protein 2 -0.00658347
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -0.0065427
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.00654186
TGFBR3 transforming growth factor, beta receptor III -0.0065112
RGS13 regulator of G-protein signaling 13 -0.00648739
IRS1 insulin receptor substrate 1 -0.00642165
CAPN1 calpain 1, (mu/I) large subunit -0.00639673
RTN2 reticulon 2 -0.00637107
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.0063605
CADM1 cell adhesion molecule 1 -0.00634006
TFPI2 tissue factor pathway inhibitor 2 -0.0063308
ANGPTL2 angiopoietin-like 2 -0.0062955
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.00629206
ENO3 enolase 3 (beta, muscle) -0.00628864
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 -0.00626701
ACTN4 actinin, alpha 4 -0.00622521
KRT19 keratin 19, type I -0.00621954
CDC20 cell division cycle 20 -0.00621926
COL10A1 collagen, type X, alpha 1 -0.0062032
DYNLL1 dynein, light chain, LC8-type 1 -0.00619649
IGFBP5 insulin-like growth factor binding protein 5 -0.00618006
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -0.00617907
RASA4 RAS p21 protein activator 4 -0.00617286
AGR2 anterior gradient 2 -0.00615627
AKAP12 A kinase (PRKA) anchor protein 12 -0.00614884
AEBP1 AE binding protein 1 -0.00613882
RRAGD Ras-related GTP binding D -0.00613655
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00613238
LPIN1 lipin 1 -0.00611742
HLA-C major histocompatibility complex, class I, C -0.00609194
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00608708
LHFP lipoma HMGIC fusion partner -0.00607284
C1R complement component 1, r subcomponent -0.00606942
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.00606114
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00605824
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00604007
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.00603486
FGFR2 fibroblast growth factor receptor 2 -0.00603039
UBE2S ubiquitin-conjugating enzyme E2S -0.00601358
PDGFD platelet derived growth factor D -0.0059993
MT1F metallothionein 1F -0.00597905
DSE dermatan sulfate epimerase -0.00597852
GBAP1 glucosidase, beta, acid pseudogene 1 -0.00593915
LY75 lymphocyte antigen 75 -0.00593756
BEX1 brain expressed, X-linked 1 -0.00593679
HEPH hephaestin -0.00593533
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00590921
ZFPM2 zinc finger protein, FOG family member 2 -0.00589822
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00589402
GREM1 gremlin 1, DAN family BMP antagonist -0.00588135
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -0.00587968
RCL1 RNA terminal phosphate cyclase-like 1 -0.00584927
SCRIB scribbled planar cell polarity protein -0.00583317
SDC1 syndecan 1 -0.00583055
IRF7 interferon regulatory factor 7 -0.00582393
PALM paralemmin -0.00580332
PDGFRL platelet-derived growth factor receptor-like -0.00579065
ZCCHC24 zinc finger, CCHC domain containing 24 -0.00578531
HLA-F major histocompatibility complex, class I, F -0.00577529
COL15A1 collagen, type XV, alpha 1 -0.0057518
GPNMB glycoprotein (transmembrane) nmb -0.00573053
DPYSL3 dihydropyrimidinase-like 3 -0.00572433
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -0.00570972
RAP1GAP2 RAP1 GTPase activating protein 2 -0.00570085
ADIPOQ adiponectin, C1Q and collagen domain containing -0.00567704
CCNA2 cyclin A2 -0.0056731
CCL2 chemokine (C-C motif) ligand 2 -0.00566563
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) -0.0056501
MFAP3L microfibrillar-associated protein 3-like -0.00564973
LOXL2 lysyl oxidase-like 2 -0.00564228
FNBP1L formin binding protein 1-like -0.00563115
NEMP1 nuclear envelope integral membrane protein 1 -0.00562877
HOXB6 homeobox B6 -0.00559316
PDGFC platelet derived growth factor C -0.00559247
PCSK6 proprotein convertase subtilisin/kexin type 6 -0.00557285
APOH apolipoprotein H (beta-2-glycoprotein I) -0.00556997
GBP2 guanylate binding protein 2, interferon-inducible -0.00556971
TNNT1 troponin T type 1 (skeletal, slow) -0.00556676
MFAP5 microfibrillar associated protein 5 -0.00556604
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -0.00555919
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00554479
QSOX1 quiescin Q6 sulfhydryl oxidase 1 -0.00552369
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) -0.00552311
SCGB1D2 secretoglobin, family 1D, member 2 -0.00552212
CRISP3 cysteine-rich secretory protein 3 -0.00551133
TGIF1 TGFB-induced factor homeobox 1 -0.00550013
GSTM3 glutathione S-transferase mu 3 (brain) -0.00549776
CBX6 chromobox homolog 6 -0.00549063
VCL vinculin -0.00548179
LAMP1 lysosomal-associated membrane protein 1 -0.00546068
ZDHHC6 zinc finger, DHHC-type containing 6 -0.00545853
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -0.00544403
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00544055
ELN elastin -0.0054275
UBA1 ubiquitin-like modifier activating enzyme 1 -0.00538924
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.00536684
SPON2 spondin 2, extracellular matrix protein -0.00535887
S100P S100 calcium binding protein P -0.00535794
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -0.00535205
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.00535038
SGCE sarcoglycan, epsilon -0.00534818
TXNIP thioredoxin interacting protein -0.00533901
SLC43A3 solute carrier family 43, member 3 -0.00533804
TUFT1 tuftelin 1 -0.0053357
ACKR1 atypical chemokine receptor 1 (Duffy blood group) -0.00533155
CRYBG1 crystallin beta-gamma domain containing 1 -0.00531543
RCAN1 regulator of calcineurin 1 -0.00529431
PNKP polynucleotide kinase 3'-phosphatase -0.00525931
LRRC15 leucine rich repeat containing 15 -0.00524729
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) -0.00524653
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00523807
LPIN2 lipin 2 -0.00522823
RNF11 ring finger protein 11 -0.00522507
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00522391
GARS1 glycyl-tRNA synthetase 1 -0.00520127
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.0051997
CLDN10 claudin 10 -0.00518672
KRT8 keratin 8, type II -0.00518272
PXDC1 PX domain containing 1 -0.00516298
RECK reversion-inducing-cysteine-rich protein with kazal motifs -0.00514148
ADRM1 adhesion regulating molecule 1 -0.00513556
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00512593
DGKZ diacylglycerol kinase, zeta -0.00512086
INSR insulin receptor -0.0051077
ARGLU1 arginine and glutamate rich 1 -0.00510154
AOX1 aldehyde oxidase 1 -0.00510123
ACADVL acyl-CoA dehydrogenase, very long chain -0.00509895
INHBE inhibin, beta E -0.0050971
UPP1 uridine phosphorylase 1 -0.00509202
C3 complement component 3 -0.00509066
DUSP5 dual specificity phosphatase 5 -0.00509037
SRPX sushi-repeat containing protein, X-linked -0.00508604
VPREB3 pre-B lymphocyte 3 -0.00508477
AMBP alpha-1-microglobulin/bikunin precursor -0.00504181
SCAF4 SR-related CTD-associated factor 4 -0.00503982
FBLN1 fibulin 1 -0.00503464
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.0050259