MASTL Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description microtubule associated serine/threonine kinase-like|This gene encodes a microtubule-associated serine/threonine kinase. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia-2. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Feb 2010] (NCBI Entrez Gene Database, 84930)
External Link https://ncbi.nlm.nih.gov/gene/84930
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Genes

499 genes differentially expressed following the MASTL gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.0137068
IFI27 interferon, alpha-inducible protein 27 0.0127437
MX1 MX dynamin-like GTPase 1 0.0127317
ZMYM2 zinc finger, MYM-type 2 0.0123457
ISG15 ISG15 ubiquitin-like modifier 0.0118279
GOLGA8A golgin A8 family, member A 0.0117451
IFI44L interferon-induced protein 44-like 0.011254
IFI6 interferon, alpha-inducible protein 6 0.011189
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.0107628
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0104333
STC2 stanniocalcin 2 0.0101124
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.0100674
NAV2 neuron navigator 2 0.00988911
CREB3L2 cAMP responsive element binding protein 3-like 2 0.00978931
KLHL21 kelch-like family member 21 0.00976876
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00976152
COL11A1 collagen, type XI, alpha 1 0.00971188
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00966377
CXCL8 chemokine (C-X-C motif) ligand 8 0.00953191
PDGFC platelet derived growth factor C 0.00929167
ABAT 4-aminobutyrate aminotransferase 0.00927777
DOCK9 dedicator of cytokinesis 9 0.0092101
TPP1 tripeptidyl peptidase I 0.00906715
MAGEA3 melanoma antigen family A3 0.00904189
MX2 MX dynamin-like GTPase 2 0.00900203
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.00895828
NOTCH2NL notch 2 N-terminal like 0.00888224
LTBP2 latent transforming growth factor beta binding protein 2 0.00887727
ARID4B AT rich interactive domain 4B (RBP1-like) 0.00886816
SIDT2 SID1 transmembrane family, member 2 0.00883378
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00876803
RRAGD Ras-related GTP binding D 0.00866072
ZC3H11A zinc finger CCCH-type containing 11A 0.00839644
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.00829941
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.00826844
GNAS GNAS complex locus 0.00818959
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.00817859
SPEN spen family transcriptional repressor 0.00813865
HMOX1 heme oxygenase 1 0.00810828
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 0.00808959
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.00799824
TENT5A terminal nucleotidyltransferase 5A 0.0079772
BST2 bone marrow stromal cell antigen 2 0.00797699
KANK1 KN motif and ankyrin repeat domains 1 0.00793902
VGLL4 vestigial-like family member 4 0.00788893
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00788789
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.00785658
IFI44 interferon-induced protein 44 0.00780436
FOXO1 forkhead box O1 0.00778972
NID2 nidogen 2 (osteonidogen) 0.00778966
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.00778915
AGO3 argonaute RISC catalytic component 3 0.00772632
SMAD3 SMAD family member 3 0.00771104
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00765685
BASP1 brain abundant, membrane attached signal protein 1 0.007639
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.00759372
SMC1A structural maintenance of chromosomes 1A 0.00757799
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.00751713
CLDN1 claudin 1 0.00748465
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.00745924
IGF2R insulin-like growth factor 2 receptor 0.00743167
TRIO trio Rho guanine nucleotide exchange factor 0.00741826
RHOBTB3 Rho-related BTB domain containing 3 0.00738393
CLGN calmegin 0.00734714
KLK11 kallikrein-related peptidase 11 0.00732134
GBP2 guanylate binding protein 2, interferon-inducible 0.00731584
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00728683
GPX3 glutathione peroxidase 3 0.00727994
KLC1 kinesin light chain 1 0.00727004
TM4SF1 transmembrane 4 L six family member 1 0.00725092
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00725056
HIST1H2BK histone cluster 1, H2bk 0.00722057
GPC3 glypican 3 0.00717899
BCOR BCL6 corepressor 0.00714002
XIC X chromosome inactivation center 0.00709868
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.0070327
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.00702611
PDZD2 PDZ domain containing 2 0.0070033
IRS2 insulin receptor substrate 2 0.00700233
ADI1 acireductone dioxygenase 1 0.00698796
MAPK6 mitogen-activated protein kinase 6 0.00697479
CTSA cathepsin A 0.00697347
PSPC1 paraspeckle component 1 0.00696517
HSPA1A heat shock 70kDa protein 1A 0.00694747
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00682398
FNDC3B fibronectin type III domain containing 3B 0.00681799
VLDLR very low density lipoprotein receptor 0.00678787
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.00678209
DDIT3 DNA-damage-inducible transcript 3 0.0067799
ITPRID2 ITPR interacting domain containing 2 0.0067624
MRPS30 mitochondrial ribosomal protein S30 0.00674098
GAS1 growth arrest-specific 1 0.00672791
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.00670585
KMT5B lysine methyltransferase 5B 0.00669851
CRTC3 CREB regulated transcription coactivator 3 0.00669437
IRF7 interferon regulatory factor 7 0.00667651
TRAPPC3 trafficking protein particle complex 3 0.00667205
LIPG lipase, endothelial 0.00665862
INPPL1 inositol polyphosphate phosphatase-like 1 0.00664977
ACSL1 acyl-CoA synthetase long-chain family member 1 0.00664085
TARS1 threonyl-tRNA synthetase 1 0.00662304
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.00661845
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 0.00661007
ITGAV integrin, alpha V 0.00660627
YARS1 tyrosyl-tRNA synthetase 1 0.0065683
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 0.00656784
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 0.00655148
WT1 Wilms tumor 1 0.0065508
N4BP2L2 NEDD4 binding protein 2-like 2 0.00654796
SUCO SUN domain containing ossification factor 0.00654526
CHD7 chromodomain helicase DNA binding protein 7 0.00653533
TXLNA taxilin alpha 0.00653419
PDE10A phosphodiesterase 10A 0.00652882
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.0065144
TBX3 T-box 3 0.00648723
FNDC3A fibronectin type III domain containing 3A 0.00648641
NUP58 nucleoporin 58 0.00648053
AIM2 absent in melanoma 2 0.00647299
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 0.00647041
KCTD5 potassium channel tetramerization domain containing 5 0.00646357
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 0.00646137
JMJD1C jumonji domain containing 1C 0.0064613
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 0.00645122
PFKP phosphofructokinase, platelet 0.00644585
SUSD6 sushi domain containing 6 0.00641394
PELI2 pellino E3 ubiquitin protein ligase family member 2 0.00639562
TLE4 transducin-like enhancer of split 4 0.00639372
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0063832
LRRC8D leucine rich repeat containing 8 family, member D 0.00636939
CCNL2 cyclin L2 0.00636648
RBM15 RNA binding motif protein 15 0.00631
AMDHD2 amidohydrolase domain containing 2 0.00630761
PLK2 polo-like kinase 2 0.00630622
CDK17 cyclin-dependent kinase 17 0.0063009
ELF1 E74-like factor 1 (ets domain transcription factor) 0.00629798
RNF6 ring finger protein (C3H2C3 type) 6 0.00629553
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.00627973
PRRC2C proline-rich coiled-coil 2C 0.00626524
SLTM SAFB-like, transcription modulator 0.00625553
ZMPSTE24 zinc metallopeptidase STE24 0.00624747
HSPH1 heat shock 105kDa/110kDa protein 1 0.00623407
BAG3 BCL2-associated athanogene 3 0.00623391
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00620909
RREB1 ras responsive element binding protein 1 0.00619159
ANKRD11 ankyrin repeat domain 11 0.0061836
MEOX1 mesenchyme homeobox 1 0.00618299
PER3 period circadian clock 3 0.00617504
ANXA3 annexin A3 0.00616352
SLC38A1 solute carrier family 38, member 1 0.00615292
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.00614603
GRN granulin 0.00613885
APOB apolipoprotein B 0.00612466
ATP9A ATPase, class II, type 9A 0.00611571
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.00610865
RTN2 reticulon 2 0.00609385
SEC11A SEC11 homolog A (S. cerevisiae) 0.00606143
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 0.00604945
GADD45B growth arrest and DNA-damage-inducible, beta 0.00602136
IGHMBP2 immunoglobulin mu binding protein 2 0.00601345
AHNAK AHNAK nucleoprotein 0.00601266
PRAME preferentially expressed antigen in melanoma 0.00599431
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.00598966
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.00598419
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 0.00598101
EFNA1 ephrin-A1 0.00596651
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 0.00594879
EPB41L3 erythrocyte membrane protein band 4.1-like 3 0.00593002
PRSS8 protease, serine, 8 0.00592269
ZNF148 zinc finger protein 148 0.0059041
MBNL2 muscleblind-like splicing regulator 2 0.00590314
DENND5A DENN/MADD domain containing 5A 0.00590088
NOTCH2 notch 2 0.00589627
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 0.00589439
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.00589322
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 0.00589203
CDV3 CDV3 homolog (mouse) 0.00587427
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 0.00587015
GTF2IRD1 GTF2I repeat domain containing 1 0.00586508
INTS6 integrator complex subunit 6 0.00585208
CDK5RAP3 CDK5 regulatory subunit associated protein 3 0.00584825
RB1 retinoblastoma 1 0.00583554
PIEZO2 piezo-type mechanosensitive ion channel component 2 0.00583344
PLAT plasminogen activator, tissue 0.0058142
STAT1 signal transducer and activator of transcription 1, 91kDa 0.00581033
GBP1 guanylate binding protein 1, interferon-inducible 0.00580467
FOXO4 forkhead box O4 0.00578843
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 0.00578486
RRBP1 ribosome binding protein 1 0.00577599
PARP4 poly (ADP-ribose) polymerase family, member 4 0.00577238
TRIB1 tribbles pseudokinase 1 0.00576535
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.00575748
NRIP1 nuclear receptor interacting protein 1 0.00574095
MAN2C1 mannosidase, alpha, class 2C, member 1 0.00572776
MED13 mediator complex subunit 13 0.00572727
TUBA4A tubulin, alpha 4a 0.00572311
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 0.00571941
BBX bobby sox homolog (Drosophila) 0.0057133
NPC1 Niemann-Pick disease, type C1 0.00569283
AADAC arylacetamide deacetylase 0.00567877
TNIK TRAF2 and NCK interacting kinase 0.0056762
CLEC2B C-type lectin domain family 2, member B 0.00566145
ANKRD12 ankyrin repeat domain 12 0.00564673
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.00563476
MYO10 myosin X 0.00561458
SETD5 SET domain containing 5 0.00561297
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 0.00561022
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.00560502
SYCP2 synaptonemal complex protein 2 0.00560005
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.00559523
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.00557784
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 0.00557071
AFF1 AF4/FMR2 family, member 1 0.00556251
SARAF store-operated calcium entry-associated regulatory factor 0.00556168
PANX1 pannexin 1 0.0055523
TACC2 transforming, acidic coiled-coil containing protein 2 0.00554106
TRIB3 tribbles pseudokinase 3 0.00553346
FYCO1 FYVE and coiled-coil domain containing 1 0.00552567
PITX2 paired-like homeodomain 2 0.00552373
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00551288
TPCN1 two pore segment channel 1 0.00550851
USP47 ubiquitin specific peptidase 47 0.00548689
AMOTL2 angiomotin like 2 0.00546859
NPIPA1 nuclear pore complex interacting protein family, member A1 0.0054663
WWC3 WWC family member 3 0.00546379
CD163 CD163 molecule 0.00545989
PNN pinin, desmosome associated protein 0.00545209
RABEP2 rabaptin, RAB GTPase binding effector protein 2 0.00544358
IGFBP1 insulin-like growth factor binding protein 1 0.00544297
RANBP2 RAN binding protein 2 0.00543874
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.0054377
USP48 ubiquitin specific peptidase 48 0.00543682
PICALM phosphatidylinositol binding clathrin assembly protein 0.00543163
IL6 interleukin 6 0.00543008
MFSD1 major facilitator superfamily domain containing 1 0.00542897
JUP junction plakoglobin 0.00542867
MACF1 microtubule-actin crosslinking factor 1 0.00540708
TULP4 tubby like protein 4 0.00539488
TRIP12 thyroid hormone receptor interactor 12 0.00537991
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.00536618
EGR1 early growth response 1 0.00536603
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00534863
ARG1 arginase 1 0.00534245
C8ORF4 chromosome 8 open reading frame 4 0.00533302
ZCCHC8 zinc finger, CCHC domain containing 8 0.00533231
RRAGC Ras-related GTP binding C 0.00532301
LYST lysosomal trafficking regulator 0.0053094
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00529509
PPL periplakin 0.00529229
ADCY9 adenylate cyclase 9 0.00528134

decreased expression

Symbol Name Standardized Value
LTF lactotransferrin -0.0140822
EMX2 empty spiracles homeobox 2 -0.0135092
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.0124936
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.0117802
FCGBP Fc fragment of IgG binding protein -0.0114597
GRB7 growth factor receptor-bound protein 7 -0.0109123
S100A8 S100 calcium binding protein A8 -0.0105761
CRYBG1 crystallin beta-gamma domain containing 1 -0.0105754
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.0105385
MOXD1 monooxygenase, DBH-like 1 -0.0102052
FABP7 fatty acid binding protein 7, brain -0.0101879
CSTA cystatin A (stefin A) -0.0101359
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.0100773
PRPF4 pre-mRNA processing factor 4 -0.0100755
CA2 carbonic anhydrase II -0.00990729
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00980027
WFDC2 WAP four-disulfide core domain 2 -0.00977582
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -0.00951315
SMAGP small cell adhesion glycoprotein -0.00946056
C3ORF14 chromosome 3 open reading frame 14 -0.00932681
TMEM14B transmembrane protein 14B -0.00931983
PADI2 peptidyl arginine deiminase, type II -0.00930461
SCGB2A1 secretoglobin, family 2A, member 1 -0.00921485
CETN2 centrin, EF-hand protein, 2 -0.00916416
KRT19 keratin 19, type I -0.00902881
SPON1 spondin 1, extracellular matrix protein -0.00897742
FGFR3 fibroblast growth factor receptor 3 -0.00897143
BAMBI BMP and activin membrane-bound inhibitor -0.00887269
RGS10 regulator of G-protein signaling 10 -0.00880192
FAR2 fatty acyl CoA reductase 2 -0.00875042
S100A7 S100 calcium binding protein A7 -0.00872644
MEF2C myocyte enhancer factor 2C -0.00870581
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00866609
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00863085
ACAT2 acetyl-CoA acetyltransferase 2 -0.00859725
IL10RB interleukin 10 receptor, beta -0.0085445
OLFM4 olfactomedin 4 -0.00851513
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 -0.00848406
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -0.00846596
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.00845117
LYZ lysozyme -0.00840695
CAPG capping protein (actin filament), gelsolin-like -0.00839419
DNTT DNA nucleotidylexotransferase -0.0083715
FASN fatty acid synthase -0.00834695
TAGLN2 transgelin 2 -0.0083236
CYB5A cytochrome b5 type A (microsomal) -0.00824597
TPM4 tropomyosin 4 -0.00821797
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00820556
CD1C CD1c molecule -0.0081926
CHKB choline kinase beta -0.00814653
SPA17 sperm autoantigenic protein 17 -0.00812374
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00809118
CASP1 caspase 1, apoptosis-related cysteine peptidase -0.00808893
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.0080599
LTB lymphotoxin beta (TNF superfamily, member 3) -0.00801644
LPAR1 lysophosphatidic acid receptor 1 -0.00792642
TUBB2A tubulin, beta 2A class IIa -0.00787324
CD52 CD52 molecule -0.00787065
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00784669
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -0.0078258
NUSAP1 nucleolar and spindle associated protein 1 -0.00777562
TUBA1A tubulin, alpha 1a -0.00774625
MXRA7 matrix-remodelling associated 7 -0.00773618
ADORA2B adenosine A2b receptor -0.00772171
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide -0.00770963
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.0076983
POSTN periostin, osteoblast specific factor -0.00768663
TSPAN1 tetraspanin 1 -0.00757567
HMGB3 high mobility group box 3 -0.00754325
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.00752184
PLIN3 perilipin 3 -0.00751553
CLCA4 chloride channel accessory 4 -0.00748727
CD48 CD48 molecule -0.00747028
MSMO1 methylsterol monooxygenase 1 -0.00746194
ADAM28 ADAM metallopeptidase domain 28 -0.0074569
FHL1 four and a half LIM domains 1 -0.00744985
HPRT1 hypoxanthine phosphoribosyltransferase 1 -0.00739135
STEAP3 STEAP family member 3, metalloreductase -0.00737833
METTL7A methyltransferase like 7A -0.00737831
FOXG1 forkhead box G1 -0.00737754
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -0.00734
RAB25 RAB25, member RAS oncogene family -0.00730777
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 -0.00728153
NDRG2 NDRG family member 2 -0.00727088
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -0.00724523
TMEM47 transmembrane protein 47 -0.00724354
SNAP25 synaptosomal-associated protein, 25kDa -0.00724183
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00723155
AREG amphiregulin -0.00718693
PDE4B phosphodiesterase 4B, cAMP-specific -0.00718177
C3 complement component 3 -0.00717077
SIVA1 SIVA1, apoptosis-inducing factor -0.00712593
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00711607
VAV3 vav 3 guanine nucleotide exchange factor -0.00706125
RFC2 replication factor C (activator 1) 2, 40kDa -0.00702801
MED6 mediator complex subunit 6 -0.00701944
IER3IP1 immediate early response 3 interacting protein 1 -0.00698048
CENPX centromere protein X -0.00695188
CA4 carbonic anhydrase IV -0.00694324
PITX3 paired-like homeodomain 3 -0.00693842
AXL AXL receptor tyrosine kinase -0.00693546
MME membrane metallo-endopeptidase -0.0068915
ATG5 autophagy related 5 -0.00688515
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00687818
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme -0.00687525
LST1 leukocyte specific transcript 1 -0.00686122
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00686035
MAGT1 magnesium transporter 1 -0.00682468
CA9 carbonic anhydrase IX -0.00682293
NIP7 NIP7, nucleolar pre-rRNA processing protein -0.00682242
CYB561 cytochrome b561 -0.00679337
BIRC5 baculoviral IAP repeat containing 5 -0.0067807
GLTP glycolipid transfer protein -0.00677918
MREG melanoregulin -0.00673661
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00671543
MUC4 mucin 4, cell surface associated -0.00671025
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00669708
TP53 tumor protein p53 -0.00669554
BLNK B-cell linker -0.00666154
DSTN destrin (actin depolymerizing factor) -0.00663999
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -0.00663811
PSRC1 proline/serine-rich coiled-coil 1 -0.00661276
DMBT1 deleted in malignant brain tumors 1 -0.00659234
UQCRC2 ubiquinol-cytochrome c reductase core protein II -0.0065873
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 -0.00657819
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00656101
RAB4A RAB4A, member RAS oncogene family -0.00650061
HILPDA hypoxia inducible lipid droplet-associated -0.00649648
DAZAP2 DAZ associated protein 2 -0.00648272
RANBP1 RAN binding protein 1 -0.00647479
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -0.00646482
MMP12 matrix metallopeptidase 12 -0.00646231
PLEK2 pleckstrin 2 -0.00645274
ACOX2 acyl-CoA oxidase 2, branched chain -0.00644046
BSPRY B-box and SPRY domain containing -0.00642552
AHCY adenosylhomocysteinase -0.00640348
ADD3 adducin 3 (gamma) -0.00638614
TUBB4B tubulin, beta 4B class IVb -0.0063825
ASRGL1 asparaginase like 1 -0.00638016
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00637168
PEA15 phosphoprotein enriched in astrocytes 15 -0.00636269
SDC1 syndecan 1 -0.00635346
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00634912
PAMR1 peptidase domain containing associated with muscle regeneration 1 -0.00633075
CEMIP cell migration inducing protein, hyaluronan binding -0.00631835
KRT20 keratin 20, type I -0.00629218
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00628689
CD200 CD200 molecule -0.0062637
ELN elastin -0.0062425
SDHAF3 succinate dehydrogenase complex assembly factor 3 -0.00620754
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -0.006202
SIRT3 sirtuin 3 -0.00618395
RAB32 RAB32, member RAS oncogene family -0.00618269
YIPF5 Yip1 domain family, member 5 -0.00617773
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00616668
MLF1 myeloid leukemia factor 1 -0.00615332
DCXR dicarbonyl/L-xylulose reductase -0.00615083
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 -0.00613771
CLDN10 claudin 10 -0.00613296
NANS N-acetylneuraminic acid synthase -0.00611094
DHDDS dehydrodolichyl diphosphate synthase -0.00610046
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -0.0060652
SIDT1 SID1 transmembrane family, member 1 -0.00604157
MPC2 mitochondrial pyruvate carrier 2 -0.00603667
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa -0.0060342
TUBB3 tubulin, beta 3 class III -0.0060214
CCK cholecystokinin -0.00600775
ISYNA1 inositol-3-phosphate synthase 1 -0.0059988
HLA-DOB major histocompatibility complex, class II, DO beta -0.00599769
ANGPT1 angiopoietin 1 -0.00598883
FXYD6 FXYD domain containing ion transport regulator 6 -0.00596537
PTGES prostaglandin E synthase -0.00595907
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -0.00595481
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.0059327
C1ORF54 chromosome 1 open reading frame 54 -0.00592655
CLU clusterin -0.00591602
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.00591234
CXCL12 chemokine (C-X-C motif) ligand 12 -0.0059003
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.00589755
SPDEF SAM pointed domain containing ETS transcription factor -0.00588244
IRF6 interferon regulatory factor 6 -0.00588189
CCNA2 cyclin A2 -0.00587351
CEP68 centrosomal protein 68kDa -0.00585299
ARHGAP32 Rho GTPase activating protein 32 -0.00584563
TMEM231 transmembrane protein 231 -0.00583931
LEFTY1 left-right determination factor 1 -0.00583007
CD8A CD8a molecule -0.00582874
MMP9 matrix metallopeptidase 9 -0.00581933
HOPX HOP homeobox -0.00581718
MCF2L MCF.2 cell line derived transforming sequence-like -0.00581709
NPM3 nucleophosmin/nucleoplasmin 3 -0.00581536
LYN LYN proto-oncogene, Src family tyrosine kinase -0.00580702
NT5E 5'-nucleotidase, ecto (CD73) -0.00580467
INSIG1 insulin induced gene 1 -0.00576291
SLC35E3 solute carrier family 35, member E3 -0.00574062
CD300A CD300a molecule -0.00574043
ADIRF adipogenesis regulatory factor -0.00572833
STMN2 stathmin 2 -0.0057125
CCNC cyclin C -0.00569083
SPINK5 serine peptidase inhibitor, Kazal type 5 -0.00569026
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00568802
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00568325
TRAF3IP2 TRAF3 interacting protein 2 -0.00567648
GINS2 GINS complex subunit 2 (Psf2 homolog) -0.00567324
CES1 carboxylesterase 1 -0.00567227
NRGN neurogranin (protein kinase C substrate, RC3) -0.00563515
TLCD3A TLC domain containing 3A -0.00562962
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -0.00562954
STOML2 stomatin (EPB72)-like 2 -0.00562307
ELP5 elongator acetyltransferase complex subunit 5 -0.00561434
THBS2 thrombospondin 2 -0.00560559
TRAM1 translocation associated membrane protein 1 -0.00558635
CPM carboxypeptidase M -0.00558549
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00556783
TREM2 triggering receptor expressed on myeloid cells 2 -0.00555979
H2AFV H2A histone family, member V -0.00555662
NEK2 NIMA-related kinase 2 -0.00554063
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 -0.0055328
GPA33 glycoprotein A33 (transmembrane) -0.00552661
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00552474
CD1E CD1e molecule -0.00552343
TP53I3 tumor protein p53 inducible protein 3 -0.00552263
HAUS4 HAUS augmin-like complex, subunit 4 -0.00551256
LY86 lymphocyte antigen 86 -0.00551192
OAZ1 ornithine decarboxylase antizyme 1 -0.00551153
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) -0.00551008
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 -0.00550465
LTBP1 latent transforming growth factor beta binding protein 1 -0.0054962
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00549442
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 -0.00548102
ASF1B anti-silencing function 1B histone chaperone -0.00546028
FXYD2 FXYD domain containing ion transport regulator 2 -0.00546027
ARL2BP ADP-ribosylation factor-like 2 binding protein -0.00545149
CRYM crystallin, mu -0.00544554
OIP5 Opa interacting protein 5 -0.00544376
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -0.00544374
TTYH1 tweety family member 1 -0.00543946
TOR3A torsin family 3, member A -0.00543592
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -0.00543084
C1ORF174 chromosome 1 open reading frame 174 -0.00542913
THBS1 thrombospondin 1 -0.00542777
TFDP1 transcription factor Dp-1 -0.00542695
FAM3C family with sequence similarity 3, member C -0.00542613
OLFM1 olfactomedin 1 -0.00541282
WDR61 WD repeat domain 61 -0.00540676
SELENBP1 selenium binding protein 1 -0.00540535
ANXA2 annexin A2 -0.00539557
METRN meteorin, glial cell differentiation regulator -0.00539361
IFT57 intraflagellar transport 57 -0.00537335
DEFB1 defensin, beta 1 -0.00536723