MATK Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description megakaryocyte-associated tyrosine kinase|The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4145)
External Link https://ncbi.nlm.nih.gov/gene/4145
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Genes

498 genes differentially expressed following the MATK gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen 0.0231523
MAGEA3 melanoma antigen family A3 0.0129393
CAV1 caveolin 1, caveolae protein, 22kDa 0.0116428
ZNF281 zinc finger protein 281 0.0114871
TYMS thymidylate synthetase 0.0107825
FGG fibrinogen gamma chain 0.0106788
NOP56 NOP56 ribonucleoprotein 0.0106437
POSTN periostin, osteoblast specific factor 0.010527
SLPI secretory leukocyte peptidase inhibitor 0.0101717
CD200 CD200 molecule 0.0101446
TRIB3 tribbles pseudokinase 3 0.00986718
MFAP5 microfibrillar associated protein 5 0.00980711
S100A9 S100 calcium binding protein A9 0.00951764
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.00950554
APOD apolipoprotein D 0.00923551
ENAH enabled homolog (Drosophila) 0.00920763
KRT81 keratin 81, type II 0.00900336
SIRPA signal-regulatory protein alpha 0.00898922
TTN titin 0.00887577
CP ceruloplasmin (ferroxidase) 0.00877272
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.00873844
FGB fibrinogen beta chain 0.00865299
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00863853
CLEC2B C-type lectin domain family 2, member B 0.00861026
FXYD5 FXYD domain containing ion transport regulator 5 0.00859965
FGA fibrinogen alpha chain 0.00854752
RGCC regulator of cell cycle 0.00850929
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.00849435
FABP4 fatty acid binding protein 4, adipocyte 0.00847747
RNPS1 RNA binding protein S1, serine-rich domain 0.00843586
KRT23 keratin 23, type I 0.00843468
NID1 nidogen 1 0.00838506
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.00835573
FKBP4 FK506 binding protein 4, 59kDa 0.00825448
OXA1L oxidase (cytochrome c) assembly 1-like 0.00822799
ORM1 orosomucoid 1 0.00816433
GJA1 gap junction protein, alpha 1, 43kDa 0.00811532
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 0.00803725
S100A7 S100 calcium binding protein A7 0.00803292
ADGRG2 adhesion G protein-coupled receptor G2 0.00802616
PDE4B phosphodiesterase 4B, cAMP-specific 0.00799725
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00792209
CKAP4 cytoskeleton-associated protein 4 0.00792109
SCGB1D2 secretoglobin, family 1D, member 2 0.00791118
CXCL10 chemokine (C-X-C motif) ligand 10 0.00789403
EMP1 epithelial membrane protein 1 0.0078013
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00778542
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00773165
ITM2A integral membrane protein 2A 0.00769239
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.00763671
KRT14 keratin 14, type I 0.00758414
PDE4DIP phosphodiesterase 4D interacting protein 0.00753988
PELI1 pellino E3 ubiquitin protein ligase 1 0.00753862
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.00744652
G0S2 G0/G1 switch 2 0.00739324
MYBPC1 myosin binding protein C, slow type 0.0073886
SLC35G2 solute carrier family 35, member G2 0.00737587
SCGB2A1 secretoglobin, family 2A, member 1 0.00733839
TWIST1 twist family bHLH transcription factor 1 0.0072939
TSPAN7 tetraspanin 7 0.00720485
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.00717527
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.00717187
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00716396
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.00714899
COL11A1 collagen, type XI, alpha 1 0.00712528
CRABP2 cellular retinoic acid binding protein 2 0.00708156
KRT17 keratin 17, type I 0.00705338
RGS5 regulator of G-protein signaling 5 0.00698239
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 0.00693152
TMEM45A transmembrane protein 45A 0.00690478
GRB7 growth factor receptor-bound protein 7 0.0068277
TM4SF1 transmembrane 4 L six family member 1 0.00675392
ABHD3 abhydrolase domain containing 3 0.00674122
PGAM1 phosphoglycerate mutase 1 (brain) 0.00672924
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 0.00670098
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.00669907
GLS glutaminase 0.00669101
COL5A2 collagen, type V, alpha 2 0.00662443
MID1IP1 MID1 interacting protein 1 0.00658649
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 0.00656822
CNN3 calponin 3, acidic 0.00654764
PEG3 paternally expressed 3 0.00654312
CCDC86 coiled-coil domain containing 86 0.00653957
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00651831
IL1RN interleukin 1 receptor antagonist 0.00649957
IRS2 insulin receptor substrate 2 0.00649587
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 0.00647391
ELANE elastase, neutrophil expressed 0.00646638
C1S complement component 1, s subcomponent 0.00646295
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 0.00644023
BTG3 BTG family, member 3 0.006436
TFRC transferrin receptor 0.00642188
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.00642151
SFRP4 secreted frizzled-related protein 4 0.00640614
PBX1 pre-B-cell leukemia homeobox 1 0.00638182
ADM adrenomedullin 0.00633372
MTA1 metastasis associated 1 0.00632596
ZFPM2 zinc finger protein, FOG family member 2 0.00631989
SPINK1 serine peptidase inhibitor, Kazal type 1 0.006287
PRAME preferentially expressed antigen in melanoma 0.00628675
IFI44L interferon-induced protein 44-like 0.00627605
MN1 meningioma (disrupted in balanced translocation) 1 0.00623112
FGF9 fibroblast growth factor 9 0.00621261
LAPTM4B lysosomal protein transmembrane 4 beta 0.00621148
ANKRD10 ankyrin repeat domain 10 0.00619643
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00616784
COL3A1 collagen, type III, alpha 1 0.00616002
PDE8B phosphodiesterase 8B 0.0061551
RABGGTB Rab geranylgeranyltransferase, beta subunit 0.00614232
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.00612459
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00610755
VSNL1 visinin-like 1 0.00610458
ADAM10 ADAM metallopeptidase domain 10 0.00609305
KLHL41 kelch-like family member 41 0.00606864
PIP prolactin-induced protein 0.00604917
NSFL1C NSFL1 (p97) cofactor (p47) 0.00600835
ELP1 elongator acetyltransferase complex subunit 1 0.00600713
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.0059888
PTBP2 polypyrimidine tract binding protein 2 0.00598132
DDR2 discoidin domain receptor tyrosine kinase 2 0.00597528
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00596759
JMJD6 jumonji domain containing 6 0.00595748
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.00595398
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 0.00594662
DIPK1A divergent protein kinase domain 1A 0.00594099
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00593524
FMOD fibromodulin 0.00592021
CAV2 caveolin 2 0.00590474
COL5A1 collagen, type V, alpha 1 0.00590114
TUT4 terminal uridylyl transferase 4 0.00589349
EREG epiregulin 0.00585111
HSPH1 heat shock 105kDa/110kDa protein 1 0.00585063
DUSP5 dual specificity phosphatase 5 0.00584428
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.00584078
TGFBR3 transforming growth factor, beta receptor III 0.00583994
MELK maternal embryonic leucine zipper kinase 0.00583596
EMC2 ER membrane protein complex subunit 2 0.00583356
CCL4 chemokine (C-C motif) ligand 4 0.00582689
COL15A1 collagen, type XV, alpha 1 0.00582549
GEM GTP binding protein overexpressed in skeletal muscle 0.00581782
HEG1 heart development protein with EGF-like domains 1 0.00581622
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.0058065
CLIC5 chloride intracellular channel 5 0.00580343
CFH complement factor H 0.00580052
ASPN asporin 0.00578623
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00576975
COL1A2 collagen, type I, alpha 2 0.00575592
TPM2 tropomyosin 2 (beta) 0.00575132
CALR calreticulin 0.00574675
TSC22D2 TSC22 domain family, member 2 0.0057395
CKS1B CDC28 protein kinase regulatory subunit 1B 0.00572237
CKM creatine kinase, muscle 0.00571664
OXTR oxytocin receptor 0.00570026
SCPEP1 serine carboxypeptidase 1 0.00569392
CRABP1 cellular retinoic acid binding protein 1 0.00568404
SLN sarcolipin 0.00568246
ADA adenosine deaminase 0.00567891
PTPRA protein tyrosine phosphatase, receptor type, A 0.0056608
PRTN3 proteinase 3 0.0056561
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.00565055
EXT1 exostosin glycosyltransferase 1 0.00562733
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.00561165
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.00561029
DCN decorin 0.0055978
RBM26 RNA binding motif protein 26 0.00558284
GBAP1 glucosidase, beta, acid pseudogene 1 0.00557519
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.00557286
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 0.00556821
CALML5 calmodulin-like 5 0.00554935
ASPH aspartate beta-hydroxylase 0.00554583
RAN RAN, member RAS oncogene family 0.00552939
SSX1 synovial sarcoma, X breakpoint 1 0.00552164
TCF4 transcription factor 4 0.00551264
FOXO1 forkhead box O1 0.0055113
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 0.00548798
TCP1 t-complex 1 0.00547325
CHGB chromogranin B 0.00547227
ACTC1 actin, alpha, cardiac muscle 1 0.00546303
AHDC1 AT hook, DNA binding motif, containing 1 0.00546242
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 0.00546206
TAGLN transgelin 0.00545624
KRT6A keratin 6A, type II 0.00542509
ZMYM2 zinc finger, MYM-type 2 0.00542123
PCDH9 protocadherin 9 0.00541357
UCK2 uridine-cytidine kinase 2 0.00541332
GBP2 guanylate binding protein 2, interferon-inducible 0.00541251
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 0.0054067
STC2 stanniocalcin 2 0.005406
ZNF654 zinc finger protein 654 0.00540299
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 0.00539309
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.00539156
LY6D lymphocyte antigen 6 complex, locus D 0.00534891
VGLL4 vestigial-like family member 4 0.00534834
ZNF131 zinc finger protein 131 0.00533409
GSDMB gasdermin B 0.00533052
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.00532883
SSPN sarcospan 0.00531248
PLIN1 perilipin 1 0.00530971
NCK1 NCK adaptor protein 1 0.00530665
CBS cystathionine-beta-synthase 0.00530612
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 0.00530234
RAB8B RAB8B, member RAS oncogene family 0.00530183
PXDN peroxidasin 0.00530149
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.00530092
CDC123 cell division cycle 123 0.00529282
ACTA1 actin, alpha 1, skeletal muscle 0.00529132
PANK2 pantothenate kinase 2 0.00528961
KRT15 keratin 15, type I 0.00528808
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00528616
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.00526887
SNAI2 snail family zinc finger 2 0.00526882
MAGEA12 melanoma antigen family A12 0.00526188
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00525589
SNX5 sorting nexin 5 0.00525041
THBS2 thrombospondin 2 0.00524589
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.00522794
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.00521848
PRNP prion protein 0.005215
TMEM230 transmembrane protein 230 0.00521334
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.00520958
EN1 engrailed homeobox 1 0.00520814
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.0051922
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 0.00518463
RECK reversion-inducing-cysteine-rich protein with kazal motifs 0.00516341
MYOM1 myomesin 1 0.005159
EIF1B eukaryotic translation initiation factor 1B 0.00515325
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00513896
MFGE8 milk fat globule-EGF factor 8 protein 0.00511826
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.00509677
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 0.00508995
EP300 E1A binding protein p300 0.00508079
CCL8 chemokine (C-C motif) ligand 8 0.00507861
OLFML2A olfactomedin-like 2A 0.005073
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00506821
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.00506545
TLN1 talin 1 0.00505904
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00505629
LHFPL2 lipoma HMGIC fusion partner-like 2 0.00505306
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 0.00505065
TRIM22 tripartite motif containing 22 0.00504047
TNF tumor necrosis factor 0.00503127
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 0.00502729
BEX1 brain expressed, X-linked 1 0.00502624
FAM198B family with sequence similarity 198, member B 0.00502464
MRPS28 mitochondrial ribosomal protein S28 0.00501978
AHCYL1 adenosylhomocysteinase-like 1 0.00500808
PDE4A phosphodiesterase 4A, cAMP-specific 0.00499706
SRRM2 serine/arginine repetitive matrix 2 0.00497966

decreased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 -0.013006
FBP1 fructose-1,6-bisphosphatase 1 -0.0128944
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.012705
EPCAM epithelial cell adhesion molecule -0.0121103
TXNIP thioredoxin interacting protein -0.0120129
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.0118009
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.0116734
TXNDC9 thioredoxin domain containing 9 -0.0115359
SLC25A46 solute carrier family 25, member 46 -0.0114501
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.0113745
METTL7A methyltransferase like 7A -0.0113686
CRYBG1 crystallin beta-gamma domain containing 1 -0.0113625
TFF1 trefoil factor 1 -0.0113352
VAMP8 vesicle-associated membrane protein 8 -0.0113281
TFPI2 tissue factor pathway inhibitor 2 -0.0110488
SLC44A4 solute carrier family 44, member 4 -0.0109621
LYZ lysozyme -0.0104742
OLFM4 olfactomedin 4 -0.0103602
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 -0.0101481
ANPEP alanyl (membrane) aminopeptidase -0.0100507
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00961337
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.00956959
TJP2 tight junction protein 2 -0.00955978
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00934275
AGR2 anterior gradient 2 -0.00927382
KRT18 keratin 18, type I -0.009262
CSTA cystatin A (stefin A) -0.00917269
CLU clusterin -0.00908685
TFF3 trefoil factor 3 (intestinal) -0.00904795
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.00901924
PCCA propionyl CoA carboxylase, alpha polypeptide -0.00880605
DACH1 dachshund family transcription factor 1 -0.00879546
CST3 cystatin C -0.00871615
NSDHL NAD(P) dependent steroid dehydrogenase-like -0.00858373
AMACR alpha-methylacyl-CoA racemase -0.00832986
QPCT glutaminyl-peptide cyclotransferase -0.00828588
SPINK4 serine peptidase inhibitor, Kazal type 4 -0.00824701
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa -0.0082361
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00819048
TCTA T-cell leukemia translocation altered -0.00800022
CYBA cytochrome b-245, alpha polypeptide -0.00797406
ACP3 acid phosphatase 3 -0.00792707
CETN2 centrin, EF-hand protein, 2 -0.00788282
KIAA0100 KIAA0100 -0.00779242
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.00779132
TACSTD2 tumor-associated calcium signal transducer 2 -0.00775568
MT1E metallothionein 1E -0.00773708
CLDN3 claudin 3 -0.0076806
EXPH5 exophilin 5 -0.00767591
ZNF185 zinc finger protein 185 (LIM domain) -0.00752746
EFNB2 ephrin-B2 -0.00747384
CGA glycoprotein hormones, alpha polypeptide -0.0074074
TUBB2A tubulin, beta 2A class IIa -0.00740607
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00738446
TM7SF2 transmembrane 7 superfamily member 2 -0.00735129
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.00728322
AQP3 aquaporin 3 (Gill blood group) -0.00718388
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00713601
DCXR dicarbonyl/L-xylulose reductase -0.00712418
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -0.00712089
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog -0.00711674
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.0070987
ADIRF adipogenesis regulatory factor -0.00709786
LTBP1 latent transforming growth factor beta binding protein 1 -0.0070248
TSPAN1 tetraspanin 1 -0.00697271
STK39 serine threonine kinase 39 -0.00695742
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.00693023
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.00692209
TARP TCR gamma alternate reading frame protein -0.00690537
NUSAP1 nucleolar and spindle associated protein 1 -0.00689346
AAMDC adipogenesis associated, Mth938 domain containing -0.00687926
BCR breakpoint cluster region -0.00684497
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.0068353
DAP death-associated protein -0.00682648
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -0.00681286
C8ORF4 chromosome 8 open reading frame 4 -0.00678843
KRT20 keratin 20, type I -0.00677511
TOMM34 translocase of outer mitochondrial membrane 34 -0.00674659
SORD sorbitol dehydrogenase -0.00671054
CAB39 calcium binding protein 39 -0.00670881
CPA3 carboxypeptidase A3 (mast cell) -0.0067033
IFT20 intraflagellar transport 20 -0.00668476
NFE2L2 nuclear factor, erythroid 2-like 2 -0.00668349
CPVL carboxypeptidase, vitellogenic-like -0.00658356
NMU neuromedin U -0.00657605
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -0.00654821
CCL19 chemokine (C-C motif) ligand 19 -0.00653704
AOC1 amine oxidase, copper containing 1 -0.00651668
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.00650938
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00649911
CTSC cathepsin C -0.0064632
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00646069
SC5D sterol-C5-desaturase -0.00645559
VDAC1 voltage-dependent anion channel 1 -0.00637719
R3HDM4 R3H domain containing 4 -0.00636879
IL7R interleukin 7 receptor -0.00634925
FLOT2 flotillin 2 -0.00634887
GMDS GDP-mannose 4,6-dehydratase -0.00633009
NANS N-acetylneuraminic acid synthase -0.00632134
NEBL nebulette -0.0062949
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -0.00629432
CHN2 chimerin 2 -0.00621333
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.00617133
HCLS1 hematopoietic cell-specific Lyn substrate 1 -0.00616742
SHROOM2 shroom family member 2 -0.00615992
ABHD11 abhydrolase domain containing 11 -0.00612957
KRCC1 lysine-rich coiled-coil 1 -0.00611651
REG1B regenerating islet-derived 1 beta -0.00606425
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -0.00598598
ANO10 anoctamin 10 -0.00598396
PRDX2 peroxiredoxin 2 -0.00596993
ZDHHC4 zinc finger, DHHC-type containing 4 -0.00590249
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -0.00589476
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.00589461
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) -0.00588987
BASP1 brain abundant, membrane attached signal protein 1 -0.00587846
MAOB monoamine oxidase B -0.0058746
TSPAN13 tetraspanin 13 -0.00587126
CREBL2 cAMP responsive element binding protein-like 2 -0.00585906
CAVIN2 caveolae associated protein 2 -0.00584977
BIRC2 baculoviral IAP repeat containing 2 -0.00584367
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -0.00584228
IFRD2 interferon-related developmental regulator 2 -0.00584212
GLYAT glycine-N-acyltransferase -0.00582361
TOR1A torsin family 1, member A (torsin A) -0.00581577
MLPH melanophilin -0.00579658
MXD4 MAX dimerization protein 4 -0.00579395
RETREG1 reticulophagy regulator 1 -0.00577646
BHLHE41 basic helix-loop-helix family, member e41 -0.00576946
CLEC7A C-type lectin domain family 7, member A -0.00576709
GRN granulin -0.00576639
MMP1 matrix metallopeptidase 1 -0.00571128
CD3D CD3d molecule, delta (CD3-TCR complex) -0.00570835
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic -0.00570736
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -0.00570161
IL1R1 interleukin 1 receptor, type I -0.00568772
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00566761
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa -0.00564697
NNMT nicotinamide N-methyltransferase -0.00564534
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.00563787
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00560355
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -0.00559299
KRT8 keratin 8, type II -0.00559011
RFK riboflavin kinase -0.0055802
HMGB3 high mobility group box 3 -0.00557684
REG1A regenerating islet-derived 1 alpha -0.00557643
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -0.00557556
ODC1 ornithine decarboxylase 1 -0.00555401
CHMP6 charged multivesicular body protein 6 -0.00555356
AP2S1 adaptor-related protein complex 2, sigma 1 subunit -0.00553034
FGFR3 fibroblast growth factor receptor 3 -0.00552422
FAXDC2 fatty acid hydroxylase domain containing 2 -0.00552209
GNG10 guanine nucleotide binding protein (G protein), gamma 10 -0.00549238
CANT1 calcium activated nucleotidase 1 -0.00548833
PCP4 Purkinje cell protein 4 -0.00548801
CXORF40B chromosome X open reading frame 40B -0.00548175
BCAS1 breast carcinoma amplified sequence 1 -0.00546942
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00546462
DNASE1L3 deoxyribonuclease I-like 3 -0.00544961
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00541708
BANK1 B-cell scaffold protein with ankyrin repeats 1 -0.00541669
SLC16A6 solute carrier family 16, member 6 -0.00541432
RAB17 RAB17, member RAS oncogene family -0.00541005
ABHD2 abhydrolase domain containing 2 -0.0054085
FOLH1B folate hydrolase 1B -0.00539691
MYRIP myosin VIIA and Rab interacting protein -0.00539551
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00539101
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.00537792
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00536793
MUC2 mucin 2, oligomeric mucus/gel-forming -0.00535114
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.00534896
ASB13 ankyrin repeat and SOCS box containing 13 -0.0053207
C6ORF48 chromosome 6 open reading frame 48 -0.00530947
ZSCAN16 zinc finger and SCAN domain containing 16 -0.00530947
GPX1 glutathione peroxidase 1 -0.00530933
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -0.00530792
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00528458
SPINT1 serine peptidase inhibitor, Kunitz type 1 -0.00527834
SH3GLB2 SH3-domain GRB2-like endophilin B2 -0.00526145
AQP1 aquaporin 1 (Colton blood group) -0.00525254
CRYL1 crystallin, lambda 1 -0.00525143
CCNG2 cyclin G2 -0.00522243
MOCS2 molybdenum cofactor synthesis 2 -0.00522001
BLNK B-cell linker -0.00521517
FKBP5 FK506 binding protein 5 -0.00521507
THAP12 THAP domain containing 12 -0.00519747
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -0.00518597
TMPRSS2 transmembrane protease, serine 2 -0.00518495
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.00517715
TRAPPC2L trafficking protein particle complex 2-like -0.00517663
PLBD1 phospholipase B domain containing 1 -0.00516468
ZMIZ2 zinc finger, MIZ-type containing 2 -0.00516323
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.00515834
PEX10 peroxisomal biogenesis factor 10 -0.00515654
GTPBP8 GTP-binding protein 8 (putative) -0.00514442
AVL9 AVL9 homolog (S. cerevisiase) -0.00514029
SFTPA2 surfactant protein A2 -0.00513499
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00511689
MT1F metallothionein 1F -0.00511058
GZMK granzyme K (granzyme 3; tryptase II) -0.00511035
SMAGP small cell adhesion glycoprotein -0.00510161
C12ORF29 chromosome 12 open reading frame 29 -0.00509982
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.00506748
VWA5A von Willebrand factor A domain containing 5A -0.00506655
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -0.00506497
CAPG capping protein (actin filament), gelsolin-like -0.0050649
MEPCE methylphosphate capping enzyme -0.00506325
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.00506156
CNPPD1 cyclin Pas1/PHO80 domain containing 1 -0.00505978
HAMP hepcidin antimicrobial peptide -0.00505952
TTC39A tetratricopeptide repeat domain 39A -0.00503647
TCEAL1 transcription elongation factor A (SII)-like 1 -0.00503013
MT1H metallothionein 1H -0.0050226
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -0.00501999
COMMD8 COMM domain containing 8 -0.00501928
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 -0.00500981
SDHAF3 succinate dehydrogenase complex assembly factor 3 -0.00498398
MAL mal, T-cell differentiation protein -0.0049697
KLK3 kallikrein-related peptidase 3 -0.00496318
WASHC3 WASH complex subunit 3 -0.00495662
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain -0.00495522
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 -0.00494895
SELENOW selenoprotein W -0.00494678
TMEM106C transmembrane protein 106C -0.00494365
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00494352
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -0.00492068
NPR3 natriuretic peptide receptor 3 -0.00490839
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.00490578
SLCO4C1 solute carrier organic anion transporter family, member 4C1 -0.00490354
DMBT1 deleted in malignant brain tumors 1 -0.00489161
ZFAND1 zinc finger, AN1-type domain 1 -0.00489139
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00488474
SLC2A4RG SLC2A4 regulator -0.00488
MED7 mediator complex subunit 7 -0.00487791
ICA1 islet cell autoantigen 1, 69kDa -0.00487298
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.00487116
SLC30A9 solute carrier family 30 (zinc transporter), member 9 -0.00486996
TSPAN12 tetraspanin 12 -0.00485724
NPY neuropeptide Y -0.00485339
PTPRK protein tyrosine phosphatase, receptor type, K -0.00485189
TYROBP TYRO protein tyrosine kinase binding protein -0.00485015
TMEM176B transmembrane protein 176B -0.00484918
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.00484878
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.00484869
TMEM14B transmembrane protein 14B -0.00483685
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 -0.00482698
ZBTB18 zinc finger and BTB domain containing 18 -0.00482277
EPB41L4B erythrocyte membrane protein band 4.1 like 4B -0.00481795
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 -0.00481563
MAPK13 mitogen-activated protein kinase 13 -0.00481348