Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
Category | transcriptomics |
Type | gene perturbation |
Description | megakaryocyte-associated tyrosine kinase|The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4145) |
External Link | https://ncbi.nlm.nih.gov/gene/4145 |
Similar Terms | |
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498 genes differentially expressed following the MATK gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
Symbol | Name | Standardized Value |
---|---|---|
PCNA | proliferating cell nuclear antigen | 0.0231523 |
MAGEA3 | melanoma antigen family A3 | 0.0129393 |
CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0116428 |
ZNF281 | zinc finger protein 281 | 0.0114871 |
TYMS | thymidylate synthetase | 0.0107825 |
FGG | fibrinogen gamma chain | 0.0106788 |
NOP56 | NOP56 ribonucleoprotein | 0.0106437 |
POSTN | periostin, osteoblast specific factor | 0.010527 |
SLPI | secretory leukocyte peptidase inhibitor | 0.0101717 |
CD200 | CD200 molecule | 0.0101446 |
TRIB3 | tribbles pseudokinase 3 | 0.00986718 |
MFAP5 | microfibrillar associated protein 5 | 0.00980711 |
S100A9 | S100 calcium binding protein A9 | 0.00951764 |
DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00950554 |
APOD | apolipoprotein D | 0.00923551 |
ENAH | enabled homolog (Drosophila) | 0.00920763 |
KRT81 | keratin 81, type II | 0.00900336 |
SIRPA | signal-regulatory protein alpha | 0.00898922 |
TTN | titin | 0.00887577 |
CP | ceruloplasmin (ferroxidase) | 0.00877272 |
ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00873844 |
FGB | fibrinogen beta chain | 0.00865299 |
SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00863853 |
CLEC2B | C-type lectin domain family 2, member B | 0.00861026 |
FXYD5 | FXYD domain containing ion transport regulator 5 | 0.00859965 |
FGA | fibrinogen alpha chain | 0.00854752 |
RGCC | regulator of cell cycle | 0.00850929 |
ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.00849435 |
FABP4 | fatty acid binding protein 4, adipocyte | 0.00847747 |
RNPS1 | RNA binding protein S1, serine-rich domain | 0.00843586 |
KRT23 | keratin 23, type I | 0.00843468 |
NID1 | nidogen 1 | 0.00838506 |
SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00835573 |
FKBP4 | FK506 binding protein 4, 59kDa | 0.00825448 |
OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00822799 |
ORM1 | orosomucoid 1 | 0.00816433 |
GJA1 | gap junction protein, alpha 1, 43kDa | 0.00811532 |
EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 0.00803725 |
S100A7 | S100 calcium binding protein A7 | 0.00803292 |
ADGRG2 | adhesion G protein-coupled receptor G2 | 0.00802616 |
PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00799725 |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00792209 |
CKAP4 | cytoskeleton-associated protein 4 | 0.00792109 |
SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00791118 |
CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00789403 |
EMP1 | epithelial membrane protein 1 | 0.0078013 |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00778542 |
DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00773165 |
ITM2A | integral membrane protein 2A | 0.00769239 |
SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.00763671 |
KRT14 | keratin 14, type I | 0.00758414 |
PDE4DIP | phosphodiesterase 4D interacting protein | 0.00753988 |
PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.00753862 |
DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.00744652 |
G0S2 | G0/G1 switch 2 | 0.00739324 |
MYBPC1 | myosin binding protein C, slow type | 0.0073886 |
SLC35G2 | solute carrier family 35, member G2 | 0.00737587 |
SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00733839 |
TWIST1 | twist family bHLH transcription factor 1 | 0.0072939 |
TSPAN7 | tetraspanin 7 | 0.00720485 |
CSNK2A1 | casein kinase 2, alpha 1 polypeptide | 0.00717527 |
DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.00717187 |
IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.00716396 |
PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00714899 |
COL11A1 | collagen, type XI, alpha 1 | 0.00712528 |
CRABP2 | cellular retinoic acid binding protein 2 | 0.00708156 |
KRT17 | keratin 17, type I | 0.00705338 |
RGS5 | regulator of G-protein signaling 5 | 0.00698239 |
IDH3B | isocitrate dehydrogenase 3 (NAD+) beta | 0.00693152 |
TMEM45A | transmembrane protein 45A | 0.00690478 |
GRB7 | growth factor receptor-bound protein 7 | 0.0068277 |
TM4SF1 | transmembrane 4 L six family member 1 | 0.00675392 |
ABHD3 | abhydrolase domain containing 3 | 0.00674122 |
PGAM1 | phosphoglycerate mutase 1 (brain) | 0.00672924 |
CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 | 0.00670098 |
SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.00669907 |
GLS | glutaminase | 0.00669101 |
COL5A2 | collagen, type V, alpha 2 | 0.00662443 |
MID1IP1 | MID1 interacting protein 1 | 0.00658649 |
PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | 0.00656822 |
CNN3 | calponin 3, acidic | 0.00654764 |
PEG3 | paternally expressed 3 | 0.00654312 |
CCDC86 | coiled-coil domain containing 86 | 0.00653957 |
SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00651831 |
IL1RN | interleukin 1 receptor antagonist | 0.00649957 |
IRS2 | insulin receptor substrate 2 | 0.00649587 |
SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 | 0.00647391 |
ELANE | elastase, neutrophil expressed | 0.00646638 |
C1S | complement component 1, s subcomponent | 0.00646295 |
STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.00644023 |
BTG3 | BTG family, member 3 | 0.006436 |
TFRC | transferrin receptor | 0.00642188 |
LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00642151 |
SFRP4 | secreted frizzled-related protein 4 | 0.00640614 |
PBX1 | pre-B-cell leukemia homeobox 1 | 0.00638182 |
ADM | adrenomedullin | 0.00633372 |
MTA1 | metastasis associated 1 | 0.00632596 |
ZFPM2 | zinc finger protein, FOG family member 2 | 0.00631989 |
SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.006287 |
PRAME | preferentially expressed antigen in melanoma | 0.00628675 |
IFI44L | interferon-induced protein 44-like | 0.00627605 |
MN1 | meningioma (disrupted in balanced translocation) 1 | 0.00623112 |
FGF9 | fibroblast growth factor 9 | 0.00621261 |
LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00621148 |
ANKRD10 | ankyrin repeat domain 10 | 0.00619643 |
GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00616784 |
COL3A1 | collagen, type III, alpha 1 | 0.00616002 |
PDE8B | phosphodiesterase 8B | 0.0061551 |
RABGGTB | Rab geranylgeranyltransferase, beta subunit | 0.00614232 |
HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.00612459 |
CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00610755 |
VSNL1 | visinin-like 1 | 0.00610458 |
ADAM10 | ADAM metallopeptidase domain 10 | 0.00609305 |
KLHL41 | kelch-like family member 41 | 0.00606864 |
PIP | prolactin-induced protein | 0.00604917 |
NSFL1C | NSFL1 (p97) cofactor (p47) | 0.00600835 |
ELP1 | elongator acetyltransferase complex subunit 1 | 0.00600713 |
TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.0059888 |
PTBP2 | polypyrimidine tract binding protein 2 | 0.00598132 |
DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00597528 |
CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00596759 |
JMJD6 | jumonji domain containing 6 | 0.00595748 |
YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.00595398 |
CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 | 0.00594662 |
DIPK1A | divergent protein kinase domain 1A | 0.00594099 |
EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00593524 |
FMOD | fibromodulin | 0.00592021 |
CAV2 | caveolin 2 | 0.00590474 |
COL5A1 | collagen, type V, alpha 1 | 0.00590114 |
TUT4 | terminal uridylyl transferase 4 | 0.00589349 |
EREG | epiregulin | 0.00585111 |
HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00585063 |
DUSP5 | dual specificity phosphatase 5 | 0.00584428 |
GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 | 0.00584078 |
TGFBR3 | transforming growth factor, beta receptor III | 0.00583994 |
MELK | maternal embryonic leucine zipper kinase | 0.00583596 |
EMC2 | ER membrane protein complex subunit 2 | 0.00583356 |
CCL4 | chemokine (C-C motif) ligand 4 | 0.00582689 |
COL15A1 | collagen, type XV, alpha 1 | 0.00582549 |
GEM | GTP binding protein overexpressed in skeletal muscle | 0.00581782 |
HEG1 | heart development protein with EGF-like domains 1 | 0.00581622 |
ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0058065 |
CLIC5 | chloride intracellular channel 5 | 0.00580343 |
CFH | complement factor H | 0.00580052 |
ASPN | asporin | 0.00578623 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.00576975 |
COL1A2 | collagen, type I, alpha 2 | 0.00575592 |
TPM2 | tropomyosin 2 (beta) | 0.00575132 |
CALR | calreticulin | 0.00574675 |
TSC22D2 | TSC22 domain family, member 2 | 0.0057395 |
CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.00572237 |
CKM | creatine kinase, muscle | 0.00571664 |
OXTR | oxytocin receptor | 0.00570026 |
SCPEP1 | serine carboxypeptidase 1 | 0.00569392 |
CRABP1 | cellular retinoic acid binding protein 1 | 0.00568404 |
SLN | sarcolipin | 0.00568246 |
ADA | adenosine deaminase | 0.00567891 |
PTPRA | protein tyrosine phosphatase, receptor type, A | 0.0056608 |
PRTN3 | proteinase 3 | 0.0056561 |
LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00565055 |
EXT1 | exostosin glycosyltransferase 1 | 0.00562733 |
TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.00561165 |
SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 0.00561029 |
DCN | decorin | 0.0055978 |
RBM26 | RNA binding motif protein 26 | 0.00558284 |
GBAP1 | glucosidase, beta, acid pseudogene 1 | 0.00557519 |
RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.00557286 |
HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) | 0.00556821 |
CALML5 | calmodulin-like 5 | 0.00554935 |
ASPH | aspartate beta-hydroxylase | 0.00554583 |
RAN | RAN, member RAS oncogene family | 0.00552939 |
SSX1 | synovial sarcoma, X breakpoint 1 | 0.00552164 |
TCF4 | transcription factor 4 | 0.00551264 |
FOXO1 | forkhead box O1 | 0.0055113 |
PSMB5 | proteasome (prosome, macropain) subunit, beta type, 5 | 0.00548798 |
TCP1 | t-complex 1 | 0.00547325 |
CHGB | chromogranin B | 0.00547227 |
ACTC1 | actin, alpha, cardiac muscle 1 | 0.00546303 |
AHDC1 | AT hook, DNA binding motif, containing 1 | 0.00546242 |
CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | 0.00546206 |
TAGLN | transgelin | 0.00545624 |
KRT6A | keratin 6A, type II | 0.00542509 |
ZMYM2 | zinc finger, MYM-type 2 | 0.00542123 |
PCDH9 | protocadherin 9 | 0.00541357 |
UCK2 | uridine-cytidine kinase 2 | 0.00541332 |
GBP2 | guanylate binding protein 2, interferon-inducible | 0.00541251 |
AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) | 0.0054067 |
STC2 | stanniocalcin 2 | 0.005406 |
ZNF654 | zinc finger protein 654 | 0.00540299 |
KCNN3 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 | 0.00539309 |
PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00539156 |
LY6D | lymphocyte antigen 6 complex, locus D | 0.00534891 |
VGLL4 | vestigial-like family member 4 | 0.00534834 |
ZNF131 | zinc finger protein 131 | 0.00533409 |
GSDMB | gasdermin B | 0.00533052 |
MYL1 | myosin, light chain 1, alkali; skeletal, fast | 0.00532883 |
SSPN | sarcospan | 0.00531248 |
PLIN1 | perilipin 1 | 0.00530971 |
NCK1 | NCK adaptor protein 1 | 0.00530665 |
CBS | cystathionine-beta-synthase | 0.00530612 |
HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | 0.00530234 |
RAB8B | RAB8B, member RAS oncogene family | 0.00530183 |
PXDN | peroxidasin | 0.00530149 |
SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | 0.00530092 |
CDC123 | cell division cycle 123 | 0.00529282 |
ACTA1 | actin, alpha 1, skeletal muscle | 0.00529132 |
PANK2 | pantothenate kinase 2 | 0.00528961 |
KRT15 | keratin 15, type I | 0.00528808 |
SH3BGRL | SH3 domain binding glutamate-rich protein like | 0.00528616 |
DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.00526887 |
SNAI2 | snail family zinc finger 2 | 0.00526882 |
MAGEA12 | melanoma antigen family A12 | 0.00526188 |
PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00525589 |
SNX5 | sorting nexin 5 | 0.00525041 |
THBS2 | thrombospondin 2 | 0.00524589 |
SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | 0.00522794 |
CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | 0.00521848 |
PRNP | prion protein | 0.005215 |
TMEM230 | transmembrane protein 230 | 0.00521334 |
ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.00520958 |
EN1 | engrailed homeobox 1 | 0.00520814 |
REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0051922 |
CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | 0.00518463 |
RECK | reversion-inducing-cysteine-rich protein with kazal motifs | 0.00516341 |
MYOM1 | myomesin 1 | 0.005159 |
EIF1B | eukaryotic translation initiation factor 1B | 0.00515325 |
GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00513896 |
MFGE8 | milk fat globule-EGF factor 8 protein | 0.00511826 |
ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.00509677 |
CYP11B1 | cytochrome P450, family 11, subfamily B, polypeptide 1 | 0.00508995 |
EP300 | E1A binding protein p300 | 0.00508079 |
CCL8 | chemokine (C-C motif) ligand 8 | 0.00507861 |
OLFML2A | olfactomedin-like 2A | 0.005073 |
NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00506821 |
HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.00506545 |
TLN1 | talin 1 | 0.00505904 |
CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00505629 |
LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.00505306 |
VPS16 | vacuolar protein sorting 16 homolog (S. cerevisiae) | 0.00505065 |
TRIM22 | tripartite motif containing 22 | 0.00504047 |
TNF | tumor necrosis factor | 0.00503127 |
CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.00502729 |
BEX1 | brain expressed, X-linked 1 | 0.00502624 |
FAM198B | family with sequence similarity 198, member B | 0.00502464 |
MRPS28 | mitochondrial ribosomal protein S28 | 0.00501978 |
AHCYL1 | adenosylhomocysteinase-like 1 | 0.00500808 |
PDE4A | phosphodiesterase 4A, cAMP-specific | 0.00499706 |
SRRM2 | serine/arginine repetitive matrix 2 | 0.00497966 |
Symbol | Name | Standardized Value |
---|---|---|
MAP7 | microtubule-associated protein 7 | -0.013006 |
FBP1 | fructose-1,6-bisphosphatase 1 | -0.0128944 |
SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.012705 |
EPCAM | epithelial cell adhesion molecule | -0.0121103 |
TXNIP | thioredoxin interacting protein | -0.0120129 |
SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0118009 |
LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0116734 |
TXNDC9 | thioredoxin domain containing 9 | -0.0115359 |
SLC25A46 | solute carrier family 25, member 46 | -0.0114501 |
IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0113745 |
METTL7A | methyltransferase like 7A | -0.0113686 |
CRYBG1 | crystallin beta-gamma domain containing 1 | -0.0113625 |
TFF1 | trefoil factor 1 | -0.0113352 |
VAMP8 | vesicle-associated membrane protein 8 | -0.0113281 |
TFPI2 | tissue factor pathway inhibitor 2 | -0.0110488 |
SLC44A4 | solute carrier family 44, member 4 | -0.0109621 |
LYZ | lysozyme | -0.0104742 |
OLFM4 | olfactomedin 4 | -0.0103602 |
GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.0101481 |
ANPEP | alanyl (membrane) aminopeptidase | -0.0100507 |
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00961337 |
SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00956959 |
TJP2 | tight junction protein 2 | -0.00955978 |
CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00934275 |
AGR2 | anterior gradient 2 | -0.00927382 |
KRT18 | keratin 18, type I | -0.009262 |
CSTA | cystatin A (stefin A) | -0.00917269 |
CLU | clusterin | -0.00908685 |
TFF3 | trefoil factor 3 (intestinal) | -0.00904795 |
SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00901924 |
PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.00880605 |
DACH1 | dachshund family transcription factor 1 | -0.00879546 |
CST3 | cystatin C | -0.00871615 |
NSDHL | NAD(P) dependent steroid dehydrogenase-like | -0.00858373 |
AMACR | alpha-methylacyl-CoA racemase | -0.00832986 |
QPCT | glutaminyl-peptide cyclotransferase | -0.00828588 |
SPINK4 | serine peptidase inhibitor, Kazal type 4 | -0.00824701 |
NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa | -0.0082361 |
SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00819048 |
TCTA | T-cell leukemia translocation altered | -0.00800022 |
CYBA | cytochrome b-245, alpha polypeptide | -0.00797406 |
ACP3 | acid phosphatase 3 | -0.00792707 |
CETN2 | centrin, EF-hand protein, 2 | -0.00788282 |
KIAA0100 | KIAA0100 | -0.00779242 |
PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | -0.00779132 |
TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00775568 |
MT1E | metallothionein 1E | -0.00773708 |
CLDN3 | claudin 3 | -0.0076806 |
EXPH5 | exophilin 5 | -0.00767591 |
ZNF185 | zinc finger protein 185 (LIM domain) | -0.00752746 |
EFNB2 | ephrin-B2 | -0.00747384 |
CGA | glycoprotein hormones, alpha polypeptide | -0.0074074 |
TUBB2A | tubulin, beta 2A class IIa | -0.00740607 |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00738446 |
TM7SF2 | transmembrane 7 superfamily member 2 | -0.00735129 |
CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00728322 |
AQP3 | aquaporin 3 (Gill blood group) | -0.00718388 |
APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00713601 |
DCXR | dicarbonyl/L-xylulose reductase | -0.00712418 |
SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.00712089 |
MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog | -0.00711674 |
LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.0070987 |
ADIRF | adipogenesis regulatory factor | -0.00709786 |
LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0070248 |
TSPAN1 | tetraspanin 1 | -0.00697271 |
STK39 | serine threonine kinase 39 | -0.00695742 |
ATP2A3 | ATPase, Ca++ transporting, ubiquitous | -0.00693023 |
UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00692209 |
TARP | TCR gamma alternate reading frame protein | -0.00690537 |
NUSAP1 | nucleolar and spindle associated protein 1 | -0.00689346 |
AAMDC | adipogenesis associated, Mth938 domain containing | -0.00687926 |
BCR | breakpoint cluster region | -0.00684497 |
PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.0068353 |
DAP | death-associated protein | -0.00682648 |
CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -0.00681286 |
C8ORF4 | chromosome 8 open reading frame 4 | -0.00678843 |
KRT20 | keratin 20, type I | -0.00677511 |
TOMM34 | translocase of outer mitochondrial membrane 34 | -0.00674659 |
SORD | sorbitol dehydrogenase | -0.00671054 |
CAB39 | calcium binding protein 39 | -0.00670881 |
CPA3 | carboxypeptidase A3 (mast cell) | -0.0067033 |
IFT20 | intraflagellar transport 20 | -0.00668476 |
NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.00668349 |
CPVL | carboxypeptidase, vitellogenic-like | -0.00658356 |
NMU | neuromedin U | -0.00657605 |
KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | -0.00654821 |
CCL19 | chemokine (C-C motif) ligand 19 | -0.00653704 |
AOC1 | amine oxidase, copper containing 1 | -0.00651668 |
COBLL1 | cordon-bleu WH2 repeat protein-like 1 | -0.00650938 |
TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00649911 |
CTSC | cathepsin C | -0.0064632 |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00646069 |
SC5D | sterol-C5-desaturase | -0.00645559 |
VDAC1 | voltage-dependent anion channel 1 | -0.00637719 |
R3HDM4 | R3H domain containing 4 | -0.00636879 |
IL7R | interleukin 7 receptor | -0.00634925 |
FLOT2 | flotillin 2 | -0.00634887 |
GMDS | GDP-mannose 4,6-dehydratase | -0.00633009 |
NANS | N-acetylneuraminic acid synthase | -0.00632134 |
NEBL | nebulette | -0.0062949 |
AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -0.00629432 |
CHN2 | chimerin 2 | -0.00621333 |
SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | -0.00617133 |
HCLS1 | hematopoietic cell-specific Lyn substrate 1 | -0.00616742 |
SHROOM2 | shroom family member 2 | -0.00615992 |
ABHD11 | abhydrolase domain containing 11 | -0.00612957 |
KRCC1 | lysine-rich coiled-coil 1 | -0.00611651 |
REG1B | regenerating islet-derived 1 beta | -0.00606425 |
PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.00598598 |
ANO10 | anoctamin 10 | -0.00598396 |
PRDX2 | peroxiredoxin 2 | -0.00596993 |
ZDHHC4 | zinc finger, DHHC-type containing 4 | -0.00590249 |
SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | -0.00589476 |
NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00589461 |
GBA3 | glucosidase, beta, acid 3 (gene/pseudogene) | -0.00588987 |
BASP1 | brain abundant, membrane attached signal protein 1 | -0.00587846 |
MAOB | monoamine oxidase B | -0.0058746 |
TSPAN13 | tetraspanin 13 | -0.00587126 |
CREBL2 | cAMP responsive element binding protein-like 2 | -0.00585906 |
CAVIN2 | caveolae associated protein 2 | -0.00584977 |
BIRC2 | baculoviral IAP repeat containing 2 | -0.00584367 |
PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | -0.00584228 |
IFRD2 | interferon-related developmental regulator 2 | -0.00584212 |
GLYAT | glycine-N-acyltransferase | -0.00582361 |
TOR1A | torsin family 1, member A (torsin A) | -0.00581577 |
MLPH | melanophilin | -0.00579658 |
MXD4 | MAX dimerization protein 4 | -0.00579395 |
RETREG1 | reticulophagy regulator 1 | -0.00577646 |
BHLHE41 | basic helix-loop-helix family, member e41 | -0.00576946 |
CLEC7A | C-type lectin domain family 7, member A | -0.00576709 |
GRN | granulin | -0.00576639 |
MMP1 | matrix metallopeptidase 1 | -0.00571128 |
CD3D | CD3d molecule, delta (CD3-TCR complex) | -0.00570835 |
CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | -0.00570736 |
RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.00570161 |
IL1R1 | interleukin 1 receptor, type I | -0.00568772 |
PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00566761 |
NDUFB1 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa | -0.00564697 |
NNMT | nicotinamide N-methyltransferase | -0.00564534 |
PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.00563787 |
IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00560355 |
UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.00559299 |
KRT8 | keratin 8, type II | -0.00559011 |
RFK | riboflavin kinase | -0.0055802 |
HMGB3 | high mobility group box 3 | -0.00557684 |
REG1A | regenerating islet-derived 1 alpha | -0.00557643 |
SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | -0.00557556 |
ODC1 | ornithine decarboxylase 1 | -0.00555401 |
CHMP6 | charged multivesicular body protein 6 | -0.00555356 |
AP2S1 | adaptor-related protein complex 2, sigma 1 subunit | -0.00553034 |
FGFR3 | fibroblast growth factor receptor 3 | -0.00552422 |
FAXDC2 | fatty acid hydroxylase domain containing 2 | -0.00552209 |
GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | -0.00549238 |
CANT1 | calcium activated nucleotidase 1 | -0.00548833 |
PCP4 | Purkinje cell protein 4 | -0.00548801 |
CXORF40B | chromosome X open reading frame 40B | -0.00548175 |
BCAS1 | breast carcinoma amplified sequence 1 | -0.00546942 |
SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00546462 |
DNASE1L3 | deoxyribonuclease I-like 3 | -0.00544961 |
SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.00541708 |
BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.00541669 |
SLC16A6 | solute carrier family 16, member 6 | -0.00541432 |
RAB17 | RAB17, member RAS oncogene family | -0.00541005 |
ABHD2 | abhydrolase domain containing 2 | -0.0054085 |
FOLH1B | folate hydrolase 1B | -0.00539691 |
MYRIP | myosin VIIA and Rab interacting protein | -0.00539551 |
BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00539101 |
MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.00537792 |
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00536793 |
MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00535114 |
LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.00534896 |
ASB13 | ankyrin repeat and SOCS box containing 13 | -0.0053207 |
C6ORF48 | chromosome 6 open reading frame 48 | -0.00530947 |
ZSCAN16 | zinc finger and SCAN domain containing 16 | -0.00530947 |
GPX1 | glutathione peroxidase 1 | -0.00530933 |
SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | -0.00530792 |
LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00528458 |
SPINT1 | serine peptidase inhibitor, Kunitz type 1 | -0.00527834 |
SH3GLB2 | SH3-domain GRB2-like endophilin B2 | -0.00526145 |
AQP1 | aquaporin 1 (Colton blood group) | -0.00525254 |
CRYL1 | crystallin, lambda 1 | -0.00525143 |
CCNG2 | cyclin G2 | -0.00522243 |
MOCS2 | molybdenum cofactor synthesis 2 | -0.00522001 |
BLNK | B-cell linker | -0.00521517 |
FKBP5 | FK506 binding protein 5 | -0.00521507 |
THAP12 | THAP domain containing 12 | -0.00519747 |
TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -0.00518597 |
TMPRSS2 | transmembrane protease, serine 2 | -0.00518495 |
LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.00517715 |
TRAPPC2L | trafficking protein particle complex 2-like | -0.00517663 |
PLBD1 | phospholipase B domain containing 1 | -0.00516468 |
ZMIZ2 | zinc finger, MIZ-type containing 2 | -0.00516323 |
SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.00515834 |
PEX10 | peroxisomal biogenesis factor 10 | -0.00515654 |
GTPBP8 | GTP-binding protein 8 (putative) | -0.00514442 |
AVL9 | AVL9 homolog (S. cerevisiase) | -0.00514029 |
SFTPA2 | surfactant protein A2 | -0.00513499 |
TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.00511689 |
MT1F | metallothionein 1F | -0.00511058 |
GZMK | granzyme K (granzyme 3; tryptase II) | -0.00511035 |
SMAGP | small cell adhesion glycoprotein | -0.00510161 |
C12ORF29 | chromosome 12 open reading frame 29 | -0.00509982 |
NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.00506748 |
VWA5A | von Willebrand factor A domain containing 5A | -0.00506655 |
MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | -0.00506497 |
CAPG | capping protein (actin filament), gelsolin-like | -0.0050649 |
MEPCE | methylphosphate capping enzyme | -0.00506325 |
GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | -0.00506156 |
CNPPD1 | cyclin Pas1/PHO80 domain containing 1 | -0.00505978 |
HAMP | hepcidin antimicrobial peptide | -0.00505952 |
TTC39A | tetratricopeptide repeat domain 39A | -0.00503647 |
TCEAL1 | transcription elongation factor A (SII)-like 1 | -0.00503013 |
MT1H | metallothionein 1H | -0.0050226 |
CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.00501999 |
COMMD8 | COMM domain containing 8 | -0.00501928 |
SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.00500981 |
SDHAF3 | succinate dehydrogenase complex assembly factor 3 | -0.00498398 |
MAL | mal, T-cell differentiation protein | -0.0049697 |
KLK3 | kallikrein-related peptidase 3 | -0.00496318 |
WASHC3 | WASH complex subunit 3 | -0.00495662 |
SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain | -0.00495522 |
NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.00494895 |
SELENOW | selenoprotein W | -0.00494678 |
TMEM106C | transmembrane protein 106C | -0.00494365 |
GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00494352 |
DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.00492068 |
NPR3 | natriuretic peptide receptor 3 | -0.00490839 |
HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.00490578 |
SLCO4C1 | solute carrier organic anion transporter family, member 4C1 | -0.00490354 |
DMBT1 | deleted in malignant brain tumors 1 | -0.00489161 |
ZFAND1 | zinc finger, AN1-type domain 1 | -0.00489139 |
SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00488474 |
SLC2A4RG | SLC2A4 regulator | -0.00488 |
MED7 | mediator complex subunit 7 | -0.00487791 |
ICA1 | islet cell autoantigen 1, 69kDa | -0.00487298 |
LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.00487116 |
SLC30A9 | solute carrier family 30 (zinc transporter), member 9 | -0.00486996 |
TSPAN12 | tetraspanin 12 | -0.00485724 |
NPY | neuropeptide Y | -0.00485339 |
PTPRK | protein tyrosine phosphatase, receptor type, K | -0.00485189 |
TYROBP | TYRO protein tyrosine kinase binding protein | -0.00485015 |
TMEM176B | transmembrane protein 176B | -0.00484918 |
ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00484878 |
ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.00484869 |
TMEM14B | transmembrane protein 14B | -0.00483685 |
HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 | -0.00482698 |
ZBTB18 | zinc finger and BTB domain containing 18 | -0.00482277 |
EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | -0.00481795 |
ATP6AP1 | ATPase, H+ transporting, lysosomal accessory protein 1 | -0.00481563 |
MAPK13 | mitogen-activated protein kinase 13 | -0.00481348 |