MAX Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description MYC associated factor X|The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] (NCBI Entrez Gene Database, 4149)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GCM_MAX
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Genes

30 co-expressed genes for MAX from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABT1 activator of basal transcription 1
BANF1 barrier to autointegration factor 1
CCAR1 cell division cycle and apoptosis regulator 1
CCDC117 coiled-coil domain containing 117
CLK4 CDC-like kinase 4
COPS2 COP9 signalosome subunit 2
CRBN cereblon
CSDE1 cold shock domain containing E1, RNA-binding
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1
FAM76B family with sequence similarity 76, member B
HNRNPR heterogeneous nuclear ribonucleoprotein R
LARP7 La ribonucleoprotein domain family, member 7
LEMD3 LEM domain containing 3
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
MAX MYC associated factor X
MEMO1 mediator of cell motility 1
MTPN myotrophin
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
NOL11 nucleolar protein 11
PCF11 PCF11 cleavage and polyadenylation factor subunit
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
RBM25 RNA binding motif protein 25
RNF138 ring finger protein 138, E3 ubiquitin protein ligase
SMAD2 SMAD family member 2
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
STAG2 stromal antigen 2
TARDBP TAR DNA binding protein
TCERG1 transcription elongation regulator 1
USPL1 ubiquitin specific peptidase like 1