MAZ Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description MYC-associated zinc finger protein (purine-binding transcription factor)| (NCBI Entrez Gene Database, 4150)
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Genes

305 genes differentially expressed following the MAZ gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
GPR75 G protein-coupled receptor 75 3.34179
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 3.34179
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 3.34179
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 3.34179
PAX3 paired box 3 3.34179
PAX7 paired box 7 3.34179
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 3.34179
ESX1 ESX homeobox 1 3.34179
GFAP glial fibrillary acidic protein 3.34179
UCN2 urocortin 2 3.34179
SKOR1 SKI family transcriptional corepressor 1 3.34179
PDZD9 PDZ domain containing 9 3.34179
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 3.34179
ZACN zinc activated ligand-gated ion channel 3.34179
MYO7B myosin VIIB 3.34179
SLC26A1 solute carrier family 26 (anion exchanger), member 1 3.34179
DUXB double homeobox B 3.34179
IL22RA1 interleukin 22 receptor, alpha 1 3.34179
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 3.34179
HES3 hes family bHLH transcription factor 3 3.34179
MYBPC3 myosin binding protein C, cardiac 3.34179
ASPA aspartoacylase 3.34179
GPR26 G protein-coupled receptor 26 3.34179
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.34179
SULT6B1 sulfotransferase family, cytosolic, 6B, member 1 3.34179
RNF133 ring finger protein 133 3.34179
CRYAA crystallin, alpha A 3.34179
OIT3 oncoprotein induced transcript 3 3.34179
PRR29 proline rich 29 3.34179
CLCF1 cardiotrophin-like cytokine factor 1 3.34179
PCDHGA11 protocadherin gamma subfamily A, 11 3.34179
DHRS9 dehydrogenase/reductase (SDR family) member 9 3.34179
DLL4 delta-like 4 (Drosophila) 3.34179
TCP11 t-complex 11, testis-specific 3.34179
PECAM1 platelet/endothelial cell adhesion molecule 1 3.34179
LYZL6 lysozyme-like 6 3.34179
TRIM77 tripartite motif containing 77 3.34179
RFPL2 ret finger protein-like 2 3.34179
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 3.34179
OR1L8 olfactory receptor, family 1, subfamily L, member 8 3.34179
LRRC10B leucine rich repeat containing 10B 3.34179
UMODL1 uromodulin-like 1 3.34179
F2 coagulation factor II (thrombin) 3.34179
NPR3 natriuretic peptide receptor 3 3.34179
GPR6 G protein-coupled receptor 6 3.34179
OR56B2 olfactory receptor family 56 subfamily B member 2 3.34179
GBP4 guanylate binding protein 4 3.34179
C3AR1 complement component 3a receptor 1 3.34179
ZAR1 zygote arrest 1 3.34179
OPRM1 opioid receptor, mu 1 3.34179
STMN4 stathmin-like 4 3.34179
OTOR otoraplin 3.34179
PDC phosducin 3.34179
TMPRSS6 transmembrane protease, serine 6 3.34179
PROX2 prospero homeobox 2 3.34179
ARX aristaless related homeobox 3.34179
GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 3.34179
C3ORF85 chromosome 3 open reading frame 85 3.34179
SPEGNB SPEG neighbor 3.34179
STRIT1 small transmembrane regulator of ion transport 1 3.34179
CSP2 CS pseudogene 2 3.34179
MINDY4B MINDY family member 4B 3.34179
SEPTIN12 septin 12 3.34179
NFILZ NFIL3 like basic leucine zipper 3.34179
ACOD1 aconitate decarboxylase 1 3.34179
DNAI7 dynein axonemal intermediate chain 7 3.34179
TRIM31 tripartite motif containing 31 3.34179
GRAP GRB2-related adaptor protein 3.34179
VSX2 visual system homeobox 2 3.34179
MAGEB3 melanoma antigen family B3 3.34179
CLDN2 claudin 2 3.34179
C4ORF17 chromosome 4 open reading frame 17 3.34179
TMEM95 transmembrane protein 95 3.34179
ATP13A4 ATPase type 13A4 3.34179
OR2A5 olfactory receptor, family 2, subfamily A, member 5 3.34179
FAM3D family with sequence similarity 3, member D 3.34179
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 3.34179
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 3.34179
NR1I3 nuclear receptor subfamily 1, group I, member 3 3.34179
GPR37L1 G protein-coupled receptor 37 like 1 3.34179
MAGIX MAGI family member, X-linked 3.34179
F5 coagulation factor V (proaccelerin, labile factor) 3.34179
CCDC42 coiled-coil domain containing 42 3.34179
FASLG Fas ligand (TNF superfamily, member 6) 3.34179
PABPC1L2B poly(A) binding protein, cytoplasmic 1-like 2B 3.34179
TAS1R1 taste receptor, type 1, member 1 3.34179
CFAP45 cilia and flagella associated protein 45 3.34179
AWAT1 acyl-CoA wax alcohol acyltransferase 1 3.34179
ACR acrosin 3.34179
CPA2 carboxypeptidase A2 (pancreatic) 3.34179
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 3.34179
ZNF703 zinc finger protein 703 3.34179
RUSC2 RUN and SH3 domain containing 2 3.34179
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 3.34179
SIGLEC16 sialic acid binding Ig-like lectin 16 (gene/pseudogene) 3.34179
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 3.34179
KCNK7 potassium channel, two pore domain subfamily K, member 7 3.34179
TMEM132E transmembrane protein 132E 3.34179
NR5A1 nuclear receptor subfamily 5, group A, member 1 3.34179
PENK proenkephalin 3.34179
PCDHGB2 protocadherin gamma subfamily B, 2 3.34179
HGFAC HGF activator 3.34179
TBPL2 TATA box binding protein like 2 3.34179
CIDEA cell death-inducing DFFA-like effector a 3.34179
GP2 glycoprotein 2 (zymogen granule membrane) 3.34179
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 3.34179
HKDC1 hexokinase domain containing 1 3.34179
NPBWR1 neuropeptides B/W receptor 1 3.34179
PCDHGA4 protocadherin gamma subfamily A, 4 3.34179
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 3.34179
PCDHGA7 protocadherin gamma subfamily A, 7 3.34179
ISL2 ISL LIM homeobox 2 3.34179
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 3.34179
COL6A5 collagen, type VI, alpha 5 3.34179
AQP8 aquaporin 8 3.34179
C8G complement component 8, gamma polypeptide 3.34179
LY96 lymphocyte antigen 96 3.34179
FATE1 fetal and adult testis expressed 1 3.34179
SYNE3 spectrin repeat containing, nuclear envelope family member 3 3.34179
CLDN34 claudin 34 3.34179
PSG3 pregnancy specific beta-1-glycoprotein 3 3.34179
GPR50 G protein-coupled receptor 50 3.34179
RGS8 regulator of G-protein signaling 8 3.34179
GRAP2 GRB2-related adaptor protein 2 3.34179
GJB3 gap junction protein, beta 3, 31kDa 3.34179
CCDC166 coiled-coil domain containing 166 3.34179
C10ORF105 chromosome 10 open reading frame 105 3.34179
BPIFC BPI fold containing family C 3.34179
WNT6 wingless-type MMTV integration site family, member 6 3.34179
EOMES eomesodermin 3.34179
EVI2A ecotropic viral integration site 2A 3.34179
GJC2 gap junction protein, gamma 2, 47kDa 3.34179
AOC1 amine oxidase, copper containing 1 3.34179
DMRTB1 DMRT-like family B with proline-rich C-terminal, 1 3.34179
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3.34179
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 3.34179
ANKRD33 ankyrin repeat domain 33 3.34179
FAM177B family with sequence similarity 177, member B 3.34179
PCDHAC2 protocadherin alpha subfamily C, 2 3.34179
EFCAB12 EF-hand calcium binding domain 12 3.34179
HMGB4 high mobility group box 4 3.34179
ALOX15B arachidonate 15-lipoxygenase, type B 3.34179
MC5R melanocortin 5 receptor 3.34179
CFAP126 cilia and flagella associated protein 126 3.34179
ERP27 endoplasmic reticulum protein 27 3.34179
NUTM2D NUT family member 2D 3.34179
WDR11 WD repeat domain 11 3.34179
CARNS1 carnosine synthase 1 3.34179
LST1 leukocyte specific transcript 1 3.34179
GH2 growth hormone 2 3.34179
CLCA4 chloride channel accessory 4 3.34179
PRAP1 proline-rich acidic protein 1 3.34179
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 3.34179
RSPH9 radial spoke head 9 homolog (Chlamydomonas) 3.30714
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3 3.30714
PRX periaxin 3.0006
WNK4 WNK lysine deficient protein kinase 4 2.95987
MAP3K4 mitogen-activated protein kinase kinase kinase 4 2.92253
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene) 2.91023
ZNF511 zinc finger protein 511 2.77375
C3 complement component 3 2.74151
SLC39A7 solute carrier family 39 (zinc transporter), member 7 2.72433
FAM91A1 family with sequence similarity 91, member A1 2.72429
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.54639
FKBP10 FK506 binding protein 10, 65 kDa 2.50381
DPYSL4 dihydropyrimidinase-like 4 2.50381
FDX2 ferredoxin 2 2.49803
PPT1 palmitoyl-protein thioesterase 1 2.48823
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) 2.47408
NUMBL numb homolog (Drosophila)-like 2.41722
SMAD2 SMAD family member 2 2.41722
MSANTD1 Myb/SANT-like DNA-binding domain containing 1 2.41176
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 2.40615
GPRC5A G protein-coupled receptor, class C, group 5, member A 2.40615
BHLHE40 basic helix-loop-helix family, member e40 2.40615
CFP complement factor properdin 2.40615
RND2 Rho family GTPase 2 2.40615
BGN biglycan 2.40615
DBR1 debranching RNA lariats 1 2.40615
OVGP1 oviductal glycoprotein 1, 120kDa 2.40615
BTNL2 butyrophilin-like 2 2.40615
RNF25 ring finger protein 25 2.40615
ZNF574 zinc finger protein 574 2.347
CFAP68 cilia and flagella associated protein 68 2.347
APAF1 apoptotic peptidase activating factor 1 2.33576
TEX19 testis expressed 19 2.33286
RTN4RL1 reticulon 4 receptor-like 1 2.33286
SYT15B synaptotagmin 15B 2.32996
LY6K lymphocyte antigen 6 complex, locus K 2.32536
ZNF444 zinc finger protein 444 2.29859
FBN2 fibrillin 2 2.27598
B9D1 B9 protein domain 1 2.27598
BRD3 bromodomain containing 3 2.2702
PPM1N protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative) 2.2412
POC1B-DUSP6 POC1B-DUSP6 readthrough 2.23404
PDCD10 programmed cell death 10 2.15369
SEPHS2 selenophosphate synthetase 2 2.13395
MRTFA myocardin related transcription factor A 2.1243
TTC1 tetratricopeptide repeat domain 1 2.1243
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 2.11321
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 2.08892
AZI2 5-azacytidine induced 2 2.08892
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 2.08801
LCMT2 leucine carboxyl methyltransferase 2 2.08488
SPICE1 spindle and centriole associated protein 1 2.07637
C1ORF74 chromosome 1 open reading frame 74 2.06642
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5 2.05744
MAST3 microtubule associated serine/threonine kinase 3 2.05096
SIDT2 SID1 transmembrane family, member 2 2.04909
FGD3 FYVE, RhoGEF and PH domain containing 3 2.04133
PWWP2A PWWP domain containing 2A 2.02794
ANKRD65 ankyrin repeat domain 65 2.00871
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 2.00498
IZUMO1 izumo sperm-egg fusion 1 2.00084
COL4A4 collagen, type IV, alpha 4 2.00084

decreased expression

Symbol Name Standardized Value
PYGM phosphorylase, glycogen, muscle -3.34179
WDR55 WD repeat domain 55 -3.34179
CST6 cystatin E/M -3.34179
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 -3.34179
TANGO2 transport and golgi organization 2 homolog (Drosophila) -3.24768
PIWIL3 piwi-like RNA-mediated gene silencing 3 -3.17424
CYS1 cystin 1 -3.17424
TUBA3D tubulin, alpha 3d -3.17424
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H -3.17424
CXCR2 chemokine (C-X-C motif) receptor 2 -3.17424
OVCH1 ovochymase 1 -3.17424
PRRT1 proline-rich transmembrane protein 1 -3.17424
ACOT12 acyl-CoA thioesterase 12 -3.17424
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 -3.17424
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 -3.17424
MAGEA4 melanoma antigen family A4 -3.17424
HORMAD2 HORMA domain containing 2 -3.17424
OSGIN1 oxidative stress induced growth inhibitor 1 -3.17424
ZNF492 zinc finger protein 492 -3.17424
C1QL2 complement component 1, q subcomponent-like 2 -3.17424
EPHA10 EPH receptor A10 -3.17424
AHSG alpha-2-HS-glycoprotein -3.17424
ERAS ES cell expressed Ras -3.17424
C6ORF58 chromosome 6 open reading frame 58 -3.17424
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B -3.17424
CFAP47 cilia and flagella associated protein 47 -3.17424
PTCHD4 patched domain containing 4 -3.13916
GALNS galactosamine (N-acetyl)-6-sulfatase -3.08291
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -3.04989
TMEM18 transmembrane protein 18 -2.8073
PNKD paroxysmal nonkinesigenic dyskinesia -2.80194
CEP95 centrosomal protein 95kDa -2.70793
CTBP1 C-terminal binding protein 1 -2.6826
UTP25 UTP25 small subunit processome component -2.62139
SOCS7 suppressor of cytokine signaling 7 -2.61541
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 -2.54639
RMDN3 regulator of microtubule dynamics 3 -2.50764
TNIP1 TNFAIP3 interacting protein 1 -2.50467
PTOV1 prostate tumor overexpressed 1 -2.48331
TUSC3 tumor suppressor candidate 3 -2.47302
TRO trophinin -2.45209
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 -2.44063
PCDHB15 protocadherin beta 15 -2.38526
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -2.38526
TMEM139 transmembrane protein 139 -2.38526
UTP4 UTP4 small subunit processome component -2.371
PRPH2 peripherin 2 (retinal degeneration, slow) -2.347
CNR2 cannabinoid receptor 2 (macrophage) -2.347
CCDC159 coiled-coil domain containing 159 -2.347
ZNF880 zinc finger protein 880 -2.33997
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G -2.30075
CD177 CD177 molecule -2.30075
DMAC1 distal membrane arm assembly component 1 -2.29631
FOXN2 forkhead box N2 -2.27598
BTD biotinidase -2.26455
NF2 neurofibromin 2 (merlin) -2.2537
FYN FYN proto-oncogene, Src family tyrosine kinase -2.24166
CENPB centromere protein B, 80kDa -2.22292
LRRC9 leucine rich repeat containing 9 -2.21247
MBOAT1 membrane bound O-acyltransferase domain containing 1 -2.20544
ZFC3H1 zinc finger, C3H1-type containing -2.18538
ZNF816 zinc finger protein 816 -2.14829
KCTD9 potassium channel tetramerization domain containing 9 -2.14829
TOR3A torsin family 3, member A -2.13421
DUS2 dihydrouridine synthase 2 -2.13395
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 -2.1243
KCTD20 potassium channel tetramerization domain containing 20 -2.12021
SCYL3 SCY1-like 3 (S. cerevisiae) -2.11054
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 -2.11054
MATK megakaryocyte-associated tyrosine kinase -2.10083
TTC31 tetratricopeptide repeat domain 31 -2.09158
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -2.09158
CLEC4C C-type lectin domain family 4, member C -2.08892
ERCC5 excision repair cross-complementation group 5 -2.08892
CNGB3 cyclic nucleotide gated channel beta 3 -2.08892
ANKRD31 ankyrin repeat domain 31 -2.08892
RTP1 receptor (chemosensory) transporter protein 1 -2.08892
ACTL8 actin-like 8 -2.08892
SMAD6 SMAD family member 6 -2.05876
RBP2 retinol binding protein 2, cellular -2.05744
IRX3 iroquois homeobox 3 -2.05744
AK7 adenylate kinase 7 -2.05242
TRPV1 transient receptor potential cation channel, subfamily V, member 1 -2.04622
OSGIN2 oxidative stress induced growth inhibitor family member 2 -2.03635
TMEM63A transmembrane protein 63A -2.0257
NME6 NME/NM23 nucleoside diphosphate kinase 6 -2.02141
CANT1 calcium activated nucleotidase 1 -2.00896
FAM76A family with sequence similarity 76, member A -2.00871
ZNF564 zinc finger protein 564 -2.0054
MKRN2OS MKRN2 opposite strand -2.00116