MC116 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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Genes

416 genes mutated in the MC116 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ABRA actin binding Rho activating protein
ACLY ATP citrate lyase
ACOT11 acyl-CoA thioesterase 11
ACTN2 actinin, alpha 2
ADAM28 ADAM metallopeptidase domain 28
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15
ADAMTSL3 ADAMTS-like 3
ADGRV1 adhesion G protein-coupled receptor V1
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
ADNP2 ADNP homeobox 2
AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6
AIF1 allograft inflammatory factor 1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
AMBRA1 autophagy/beclin-1 regulator 1
ANGPT1 angiopoietin 1
ANKRD17 ankyrin repeat domain 17
APOB apolipoprotein B
APOBR apolipoprotein B receptor
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARID4A AT rich interactive domain 4A (RBP1-like)
ARL4C ADP-ribosylation factor-like 4C
ARSA arylsulfatase A
ATN1 atrophin 1
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
ATXN3 ataxin 3
AVEN apoptosis, caspase activation inhibitor
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BAHCC1 BAH domain and coiled-coil containing 1
BCL6 B-cell CLL/lymphoma 6
BCL9 B-cell CLL/lymphoma 9
BIN1 bridging integrator 1
BIRC6 baculoviral IAP repeat containing 6
BRD1 bromodomain containing 1
BTG2 BTG family, member 2
C2CD3 C2 calcium-dependent domain containing 3
C4A complement component 4A (Rodgers blood group)
C4B complement component 4B (Chido blood group)
C5 complement component 5
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CCDC129 coiled-coil domain containing 129
CD163L1 CD163 molecule-like 1
CDC123 cell division cycle 123
CDH12 cadherin 12, type 2 (N-cadherin 2)
CEMIP cell migration inducing protein, hyaluronan binding
CEP131 centrosomal protein 131kDa
CEP89 centrosomal protein 89kDa
CER1 cerberus 1, DAN family BMP antagonist
CFAP74 cilia and flagella associated protein 74
CHD2 chromodomain helicase DNA binding protein 2
CHN1 chimerin 1
CHPT1 choline phosphotransferase 1
CIB3 calcium and integrin binding family member 3
CIPC CLOCK-interacting pacemaker
CLCC1 chloride channel CLIC-like 1
CLGN calmegin
CMTR1 cap methyltransferase 1
CMYA5 cardiomyopathy associated 5
CNTNAP1 contactin associated protein 1
CNTNAP2 contactin associated protein-like 2
COL14A1 collagen, type XIV, alpha 1
COL20A1 collagen, type XX, alpha 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CROT carnitine O-octanoyltransferase
CRTC2 CREB regulated transcription coactivator 2
CSMD1 CUB and Sushi multiple domains 1
CTNNA2 catenin (cadherin-associated protein), alpha 2
CUBN cubilin (intrinsic factor-cobalamin receptor)
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DARS2 aspartyl-tRNA synthetase 2, mitochondrial
DCLK1 doublecortin-like kinase 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
DENND4B DENN/MADD domain containing 4B
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DNAH1 dynein, axonemal, heavy chain 1
DNAH11 dynein, axonemal, heavy chain 11
DNAH6 dynein, axonemal, heavy chain 6
DNAI1 dynein, axonemal, intermediate chain 1
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNTTIP1 deoxynucleotidyltransferase, terminal, interacting protein 1
DOCK2 dedicator of cytokinesis 2
DOK7 docking protein 7
DST dystonin
DSTYK dual serine/threonine and tyrosine protein kinase
DTNA dystrobrevin, alpha
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
DZIP1 DAZ interacting zinc finger protein 1
DZIP3 DAZ interacting zinc finger protein 3
E2F8 E2F transcription factor 8
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EFS embryonal Fyn-associated substrate
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2
ELMOD2 ELMO/CED-12 domain containing 2
ELOVL7 ELOVL fatty acid elongase 7
EPC1 enhancer of polycomb homolog 1 (Drosophila)
EPHA5 EPH receptor A5
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1
ESAM endothelial cell adhesion molecule
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
EVC Ellis van Creveld protein
EVX1 even-skipped homeobox 1
EXOC6B exocyst complex component 6B
EYS eyes shut homolog (Drosophila)
FADS1 fatty acid desaturase 1
FAM135B family with sequence similarity 135, member B
FAM13B family with sequence similarity 13, member B
FAM192A family with sequence similarity 192, member A
FAM205BP transmembrane protein C9orf144B pseudogene
FAM73B family with sequence similarity 73, member B
FAM84A family with sequence similarity 84, member A
FAM90A1 family with sequence similarity 90, member A1
FBLN2 fibulin 2
FBXO11 F-box protein 11
FBXO42 F-box protein 42
FHOD3 formin homology 2 domain containing 3
FKBP15 FK506 binding protein 15, 133kDa
FLAD1 flavin adenine dinucleotide synthetase 1
FMNL3 formin-like 3
FOXS1 forkhead box S1
FSD1 fibronectin type III and SPRY domain containing 1
GEM GTP binding protein overexpressed in skeletal muscle
GFAP glial fibrillary acidic protein
GGT1 gamma-glutamyltransferase 1
GLIPR1L2 GLI pathogenesis-related 1 like 2
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GOPC golgi-associated PDZ and coiled-coil motif containing
GPC6 glypican 6
GRIK1 glutamate receptor, ionotropic, kainate 1
GRM5 glutamate receptor, metabotropic 5
GTPBP4 GTP binding protein 4
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
H1FNT H1 histone family, member N, testis-specific
HAUS6 HAUS augmin-like complex, subunit 6
HDDC3 HD domain containing 3
HGFAC HGF activator
HIRA histone cell cycle regulator
HIST1H1E histone cluster 1, H1e
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMGN1 high mobility group nucleosome binding domain 1
HNRNPM heterogeneous nuclear ribonucleoprotein M
HSPG2 heparan sulfate proteoglycan 2
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HYDIN HYDIN, axonemal central pair apparatus protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFNL2 interferon, lambda 2
IFT22 intraflagellar transport 22
IL1RAP interleukin 1 receptor accessory protein
IQUB IQ motif and ubiquitin domain containing
IRF5 interferon regulatory factor 5
ISM1 isthmin 1, angiogenesis inhibitor
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein-like 2
JAK2 Janus kinase 2
KAT2A K(lysine) acetyltransferase 2A
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3
KIAA1024 KIAA1024
KIAA1429 KIAA1429
KIF19 kinesin family member 19
KIF26B kinesin family member 26B
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KLF10 Kruppel-like factor 10
KLHDC8A kelch domain containing 8A
KLHL30 kelch-like family member 30
KMT2D lysine (K)-specific methyltransferase 2D
KNTC1 kinetochore associated 1
KRT24 keratin 24, type I
KRTAP10-4 keratin associated protein 10-4
KRTAP5-7 keratin associated protein 5-7
KRTAP9-8 keratin associated protein 9-8
LAMB2 laminin, beta 2 (laminin S)
LDHB lactate dehydrogenase B
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LHFPL4 lipoma HMGIC fusion partner-like 4
LIAS lipoic acid synthetase
LIG4 ligase IV, DNA, ATP-dependent
LOH12CR1 loss of heterozygosity, 12, chromosomal region 1
LRP1B low density lipoprotein receptor-related protein 1B
LRPPRC leucine-rich pentatricopeptide repeat containing
LRRC16B leucine rich repeat containing 16B
LRRC27 leucine rich repeat containing 27
LRRC39 leucine rich repeat containing 39
LRRC49 leucine rich repeat containing 49
LRRC7 leucine rich repeat containing 7
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LTN1 listerin E3 ubiquitin protein ligase 1
MADD MAP-kinase activating death domain
MAN2A2 mannosidase, alpha, class 2A, member 2
MAP1B microtubule-associated protein 1B
MAPK14 mitogen-activated protein kinase 14
MAPKAP1 mitogen-activated protein kinase associated protein 1
MARCH2 membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
MARK1 MAP/microtubule affinity-regulating kinase 1
MBD1 methyl-CpG binding domain protein 1
MED16 mediator complex subunit 16
MET MET proto-oncogene, receptor tyrosine kinase
MFAP3L microfibrillar-associated protein 3-like
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MIDN midnolin
MMP20 matrix metallopeptidase 20
MPDZ multiple PDZ domain protein
MRGPRX4 MAS-related GPR, member X4
MSLNL mesothelin-like
MSRA methionine sulfoxide reductase A
MUC17 mucin 17, cell surface associated
MUC4 mucin 4, cell surface associated
MYBPHL myosin binding protein H-like
MYH15 myosin, heavy chain 15
MYO7A myosin VIIA
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
MYOCD myocardin
NBPF7 neuroblastoma breakpoint family, member 7
NCOR2 nuclear receptor corepressor 2
NEK2 NIMA-related kinase 2
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NHEJ1 nonhomologous end-joining factor 1
NMBR neuromedin B receptor
NNT nicotinamide nucleotide transhydrogenase
NOS1 nitric oxide synthase 1 (neuronal)
NPIPB15 nuclear pore complex interacting protein family, member B15
NPTX1 neuronal pentraxin I
NSUN5 NOP2/Sun domain family, member 5
NUP205 nucleoporin 205kDa
OPA1 optic atrophy 1 (autosomal dominant)
OPHN1 oligophrenin 1
OPRM1 opioid receptor, mu 1
OR10A3 olfactory receptor, family 10, subfamily A, member 3
OR10H2 olfactory receptor, family 10, subfamily H, member 2
OR2A14 olfactory receptor, family 2, subfamily A, member 14
OR2F2 olfactory receptor, family 2, subfamily F, member 2
OR51J1 olfactory receptor, family 51, subfamily J, member 1 (gene/pseudogene)
OR5AR1 olfactory receptor, family 5, subfamily AR, member 1 (gene/pseudogene)
OR5L2 olfactory receptor, family 5, subfamily L, member 2
OR8D2 olfactory receptor, family 8, subfamily D, member 2 (gene/pseudogene)
OR8S1 olfactory receptor, family 8, subfamily S, member 1
OTOGL otogelin-like
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARP6 poly (ADP-ribose) polymerase family, member 6
PAWR PRKC, apoptosis, WT1, regulator
PAX8 paired box 8
PCBP1 poly(rC) binding protein 1
PCDH11Y protocadherin 11 Y-linked
PCDHB3 protocadherin beta 3
PCDHGC4 protocadherin gamma subfamily C, 4
PCLO piccolo presynaptic cytomatrix protein
PDE4A phosphodiesterase 4A, cAMP-specific
PDE8B phosphodiesterase 8B
PDGFRL platelet-derived growth factor receptor-like
PEX11G peroxisomal biogenesis factor 11 gamma
PHF6 PHD finger protein 6
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIKFYVE phosphoinositide kinase, FYVE finger containing
PLA2G2C phospholipase A2, group IIC
PLA2G4F phospholipase A2, group IVF
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POM121 POM121 transmembrane nucleoporin
POMT1 protein-O-mannosyltransferase 1
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPIAL4G peptidylprolyl isomerase A (cyclophilin A)-like 4G
PPP1R21 protein phosphatase 1, regulatory subunit 21
PPP1R26 protein phosphatase 1, regulatory subunit 26
PRAME preferentially expressed antigen in melanoma
PRDM16 PR domain containing 16
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRKG1 protein kinase, cGMP-dependent, type I
PRRC2A proline-rich coiled-coil 2A
PSG1 pregnancy specific beta-1-glycoprotein 1
PSG2 pregnancy specific beta-1-glycoprotein 2
PSG4 pregnancy specific beta-1-glycoprotein 4
PTCHD3 patched domain containing 3
PTEN phosphatase and tensin homolog
PTP4A2 protein tyrosine phosphatase type IVA, member 2
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTPRA protein tyrosine phosphatase, receptor type, A
PTPRF protein tyrosine phosphatase, receptor type, F
PUM2 pumilio RNA-binding family member 2
PYCR2 pyrroline-5-carboxylate reductase family, member 2
QRICH2 glutamine rich 2
RAB1A RAB1A, member RAS oncogene family
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RAD50 RAD50 homolog (S. cerevisiae)
RANBP2 RAN binding protein 2
RAP1GAP RAP1 GTPase activating protein
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RARS arginyl-tRNA synthetase
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM27 RNA binding motif protein 27
RFC2 replication factor C (activator 1) 2, 40kDa
RGPD3 RANBP2-like and GRIP domain containing 3
RGS9BP regulator of G protein signaling 9 binding protein
RNF20 ring finger protein 20, E3 ubiquitin protein ligase
RNF32 ring finger protein 32
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RORA RAR-related orphan receptor A
RP1 retinitis pigmentosa 1 (autosomal dominant)
RP1L1 retinitis pigmentosa 1-like 1
RPL18A ribosomal protein L18a
RPUSD3 RNA pseudouridylate synthase domain containing 3
RYR3 ryanodine receptor 3
SACK1B scaffolding CK1 anchoring protein B
SALL4 spalt-like transcription factor 4
SAMD9L sterile alpha motif domain containing 9-like
SCAI suppressor of cancer cell invasion
SCN11A sodium channel, voltage gated, type XI alpha subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SCRIB scribbled planar cell polarity protein
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
SESN3 sestrin 3
SEZ6 seizure related 6 homolog (mouse)
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SFMBT2 Scm-like with four mbt domains 2
SH2D5 SH2 domain containing 5
SH3PXD2B SH3 and PX domains 2B
SIN3B SIN3 transcription regulator family member B
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC30A2 solute carrier family 30 (zinc transporter), member 2
SLC35E4 solute carrier family 35, member E4
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLITRK5 SLIT and NTRK-like family, member 5
SLX4 SLX4 structure-specific endonuclease subunit
SMAD5 SMAD family member 5
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SPINK9 serine peptidase inhibitor, Kazal type 9
SPOP speckle-type POZ protein
SPTBN5 spectrin, beta, non-erythrocytic 5
SRR serine racemase
SRSF1 serine/arginine-rich splicing factor 1
STAB2 stabilin 2
STK17A serine/threonine kinase 17a
STOX2 storkhead box 2
STYK1 serine/threonine/tyrosine kinase 1
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4
SUZ12 SUZ12 polycomb repressive complex 2 subunit
SYNE1 spectrin repeat containing, nuclear envelope 1
SYTL2 synaptotagmin-like 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TACC2 transforming, acidic coiled-coil containing protein 2
TAS2R31 taste receptor, type 2, member 31
TAS2R8 taste receptor, type 2, member 8
TCHHL1 trichohyalin-like 1
TENM2 teneurin transmembrane protein 2
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TEX261 testis expressed 261
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia)
TIAM1 T-cell lymphoma invasion and metastasis 1
TM2D1 TM2 domain containing 1
TMEM106C transmembrane protein 106C
TMTC3 transmembrane and tetratricopeptide repeat containing 3
TOX4 TOX high mobility group box family member 4
TP53 tumor protein p53
TPSB2 tryptase beta 2 (gene/pseudogene)
TRDN triadin
TRIM34 tripartite motif containing 34
TRIM6-TRIM34 TRIM6-TRIM34 readthrough
TRIOBP TRIO and F-actin binding protein
TROVE2 TROVE domain family, member 2
TTC28 tetratricopeptide repeat domain 28
TTLL12 tubulin tyrosine ligase-like family member 12
TUB tubby bipartite transcription factor
TUSC3 tumor suppressor candidate 3
UBR1 ubiquitin protein ligase E3 component n-recognin 1
UBXN6 UBX domain protein 6
UFM1 ubiquitin-fold modifier 1
UNC5C unc-5 homolog C (C. elegans)
UQCRB ubiquinol-cytochrome c reductase binding protein
USP26 ubiquitin specific peptidase 26
USP32 ubiquitin specific peptidase 32
USP4 ubiquitin specific peptidase 4 (proto-oncogene)
UVSSA UV-stimulated scaffold protein A
VASP vasodilator-stimulated phosphoprotein
VAV3 vav 3 guanine nucleotide exchange factor
VCAM1 vascular cell adhesion molecule 1
VIM vimentin
VN2R1P vomeronasal 2 receptor 1 pseudogene
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae)
VTN vitronectin
WAC WW domain containing adaptor with coiled-coil
WNK3 WNK lysine deficient protein kinase 3
WNT10B wingless-type MMTV integration site family, member 10B
YLPM1 YLP motif containing 1
ZBP1 Z-DNA binding protein 1
ZBTB34 zinc finger and BTB domain containing 34
ZC3H4 zinc finger CCCH-type containing 4
ZFC3H1 zinc finger, C3H1-type containing
ZFHX3 zinc finger homeobox 3
ZMYM6 zinc finger, MYM-type 6
ZNF121 zinc finger protein 121
ZNF468 zinc finger protein 468
ZNF566 zinc finger protein 566
ZNF598 zinc finger protein 598
ZNF680 zinc finger protein 680
ZNF808 zinc finger protein 808
ZNF827 zinc finger protein 827
ZNF862 zinc finger protein 862
ZNF98 zinc finger protein 98
ZNRF4 zinc and ring finger 4