MCAS Gene Set

Dataset CCLE Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description cell line derived from ovary (Cancer Cell Line Encyclopedia)
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Genes

306 genes with high or low expression in MCAS relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
C6ORF15 chromosome 6 open reading frame 15 2.65491
KRT19P2 keratin 19 pseudogene 2 2.54677
PIH1D3 PIH1 domain containing 3 2.33619
PADI1 peptidyl arginine deiminase, type I 2.26132
PSORS1C1 psoriasis susceptibility 1 candidate 1 2.24919
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12 2.22922
CSTL1 cystatin-like 1 2.20918
GLRX3 glutaredoxin 3 2.20776
TRIM29 tripartite motif containing 29 2.20636
SAV1 salvador family WW domain containing protein 1 2.16912
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 2.15816
TRAV34 T cell receptor alpha variable 34 2.14613
LINC01565 long intergenic non-protein coding RNA 1565 2.1278
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 2.09973
OR5P3 olfactory receptor, family 5, subfamily P, member 3 2.05587
TAS2R9 taste receptor, type 2, member 9 2.05239
PRSS1 protease, serine, 1 (trypsin 1) 2.04754
NABP1 nucleic acid binding protein 1 2.02235
PPIF peptidylprolyl isomerase F 1.99684
LETM2 leucine zipper-EF-hand containing transmembrane protein 2 1.98431
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 1.97596
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 1.95811
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 1.92267
RFC2 replication factor C (activator 1) 2, 40kDa 1.89746
OR51B4 olfactory receptor, family 51, subfamily B, member 4 1.88411
ADGRF1 adhesion G protein-coupled receptor F1 1.8828
MRPL43 mitochondrial ribosomal protein L43 1.8795
OR51B5 olfactory receptor, family 51, subfamily B, member 5 1.86964
CTBP2 C-terminal binding protein 2 1.84282
NT5DC4 5'-nucleotidase domain containing 4 1.81599
ITPKA inositol-trisphosphate 3-kinase A 1.81038
TUBGCP2 tubulin, gamma complex associated protein 2 1.80501
PEG10 paternally expressed 10 1.80083
TRPC7 transient receptor potential cation channel, subfamily C, member 7 1.79731
NKAIN3 Na+/K+ transporting ATPase interacting 3 1.78736
PRSS3 protease, serine, 3 1.78673
DUSP5 dual specificity phosphatase 5 1.78198
LOC100505782 uncharacterized LOC100505782 1.77969
FLJ32955 1.77754
RNMT RNA (guanine-7-) methyltransferase 1.77643
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene) 1.77376
ATE1 arginyltransferase 1 1.75716
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 1.75706
PHACTR3 phosphatase and actin regulator 3 1.75308
PORCN porcupine homolog (Drosophila) 1.75162
NSAP11 nervous system abundant protein 11 1.75058
MIP major intrinsic protein of lens fiber 1.74719
SLC4A11 solute carrier family 4, sodium borate transporter, member 11 1.74339
MARC2 mitochondrial amidoxime reducing component 2 1.73986
CFLAR-AS1 CFLAR antisense RNA 1 1.73537
C10ORF55 chromosome 10 open reading frame 55 1.7128
LINC01553 long intergenic non-protein coding RNA 1553 1.71255
NLRP10 NLR family, pyrin domain containing 10 1.71171
LRRC42 leucine rich repeat containing 42 1.71064
AFAP1-AS1 AFAP1 antisense RNA 1 1.70325
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 1.69786
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 1.69697
DNAH11 dynein, axonemal, heavy chain 11 1.69378
HBEGF heparin-binding EGF-like growth factor 1.68998
DYSF dysferlin 1.67582
CUTC cutC copper transporter 1.67029
SFTA1P surfactant associated 1, pseudogene 1.66145
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 1.65454
PRMT5 protein arginine methyltransferase 5 1.65319
GOLGA6L2 golgin A6 family-like 2 1.65281
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 1.65138
ZC3H11D zinc finger CCCH-type containing 11D 1.64916
TGM4 transglutaminase 4 1.64668
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 1.64231
ZSCAN12P1 zinc finger and SCAN domain containing 12 pseudogene 1 1.61516
CDK7 cyclin-dependent kinase 7 1.61366
GPRC5B G protein-coupled receptor, class C, group 5, member B 1.61053
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 1.60791
RFPL2 ret finger protein-like 2 1.59794
OR51B2 olfactory receptor, family 51, subfamily B, member 2 (gene/pseudogene) 1.59763
WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 1.59524
NHLRC2 NHL repeat containing 2 1.59504
LMOD3 leiomodin 3 (fetal) 1.59455
SMC3 structural maintenance of chromosomes 3 1.59065
CXCL5 chemokine (C-X-C motif) ligand 5 1.58956
TGM6 transglutaminase 6 1.58308
HBE1 hemoglobin, epsilon 1 1.57453
PPP2R2D protein phosphatase 2, regulatory subunit B, delta 1.57378
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 1.55617
RGS7 regulator of G-protein signaling 7 1.55575
MPC1 mitochondrial pyruvate carrier 1 1.55306
LHFPL5 lipoma HMGIC fusion partner-like 5 1.55243
EXOSC1 exosome component 1 1.54616
PTPN2 protein tyrosine phosphatase, non-receptor type 2 1.54481
DKFZP434J0226 uncharacterized LOC93429 1.53318
ABHD11 abhydrolase domain containing 11 1.53033
BTF3P11 basic transcription factor 3 pseudogene 11 1.52861
ZNF655 zinc finger protein 655 1.52684
GPHB5 glycoprotein hormone beta 5 1.52187
LRRN4 leucine rich repeat neuronal 4 1.52043
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 1.51967
FAM205A family with sequence similarity 205, member A 1.51893
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 1.51742
HMGA1 high mobility group AT-hook 1 1.51382
BCCIP BRCA2 and CDKN1A interacting protein 1.51097
IL36A interleukin 36, alpha 1.51096
NEURL3 neuralized E3 ubiquitin protein ligase 3 1.5085
PRSS3P2 protease, serine, 3 pseudogene 2 1.50425
ECD ecdysoneless homolog (Drosophila) 1.50415
DAP death-associated protein 1.50403
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 1.5004
TOP3B topoisomerase (DNA) III beta 1.49584
FAM65C family with sequence similarity 65, member C 1.49464
DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21 1.49185
NT5C 5', 3'-nucleotidase, cytosolic 1.49175
TMEM171 transmembrane protein 171 1.49174
ZNF33B zinc finger protein 33B 1.48863
DOCK9 dedicator of cytokinesis 9 1.48702
ELOVL6 ELOVL fatty acid elongase 6 1.4834
IRAK2 interleukin-1 receptor-associated kinase 2 1.47942
DNAH12 dynein, axonemal, heavy chain 12 1.47904
HNRNPF heterogeneous nuclear ribonucleoprotein F 1.47828
POLB polymerase (DNA directed), beta 1.47714
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.47307
IGHV2-5 immunoglobulin heavy variable 2-5 1.47176
GREB1L growth regulation by estrogen in breast cancer-like 1.46841
NF2 neurofibromin 2 (merlin) 1.4684
LOC100129098 serine/arginine repetitive matrix protein 2-like 1.46493
ADORA2B adenosine A2b receptor 1.46134
MYL2 myosin, light chain 2, regulatory, cardiac, slow 1.46032
TRAV13-2 T cell receptor alpha variable 13-2 1.46027
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 1.45817
LMO7 LIM domain 7 1.45704
NTHL1 nth endonuclease III-like 1 (E. coli) 1.4555
ZIM3 zinc finger, imprinted 3 1.44923
CIB4 calcium and integrin binding family member 4 1.44681
DVL1 dishevelled segment polarity protein 1 1.44571
PTPN12 protein tyrosine phosphatase, non-receptor type 12 1.44482
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) 1.43995
SMNDC1 survival motor neuron domain containing 1 1.43453
WNT7B wingless-type MMTV integration site family, member 7B 1.43124
MRPS16 mitochondrial ribosomal protein S16 1.42998
ANO1 anoctamin 1, calcium activated chloride channel 1.42859
ADRA1A adrenoceptor alpha 1A 1.42783
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) 1.42764
ACTL7A actin-like 7A 1.42581
KRT6B keratin 6B, type II 1.4224
GJB5 gap junction protein, beta 5, 31.1kDa 1.42181
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 1.41996
UCA1 urothelial cancer associated 1 (non-protein coding) 1.41766
SPTBN5 spectrin, beta, non-erythrocytic 5 1.41338
LOC339298 uncharacterized LOC339298 1.41279
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa 1.41275
HIST1H1D histone cluster 1, H1d 1.41172
KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1 1.40701
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 1.40681
MCMBP minichromosome maintenance complex binding protein 1.40478
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 1.40074
HSPB11 heat shock protein family B (small), member 11 1.39997
SCGB1D1 secretoglobin, family 1D, member 1 1.39887
GMPPB GDP-mannose pyrophosphorylase B 1.39798
NLRP13 NLR family, pyrin domain containing 13 1.39654
STX1A syntaxin 1A (brain) 1.39044
CTRC chymotrypsin C (caldecrin) 1.39001
CSN1S1 casein alpha s1 1.38679
OR2H1 olfactory receptor, family 2, subfamily H, member 1 1.38499
LINC00310 long intergenic non-protein coding RNA 310 1.38285
SEC24C SEC24 family member C 1.3821
RPP30 ribonuclease P/MRP 30kDa subunit 1.38145
FAM181A-AS1 FAM181A antisense RNA 1 1.38121
KLK11 kallikrein-related peptidase 11 1.37778
CLDN4 claudin 4 1.37438
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.37265
ZNF511 zinc finger protein 511 1.37156
HLA-F-AS1 HLA-F antisense RNA 1 1.37057
DMRTA1 DMRT-like family A1 1.37044
ZBED2 zinc finger, BED-type containing 2 1.36902
TRAV9-2 T cell receptor alpha variable 9-2 1.36374
LOC100130992 uncharacterized LOC100130992 1.36309
CELA2A chymotrypsin-like elastase family, member 2A 1.36216
VSIG1 V-set and immunoglobulin domain containing 1 1.35964
KIAA1211L KIAA1211-like 1.35888
TFAM transcription factor A, mitochondrial 1.35812
AADAC arylacetamide deacetylase 1.35571
IL33R interleukin 33 receptor 1.35401
FOXN1 forkhead box N1 1.35201
KIAA1875 KIAA1875 1.3518
LOC286083 uncharacterized LOC286083 1.35068
PROK1 prokineticin 1 1.35001
PCBD2 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 1.34942

low expression

Symbol Name Standardized Value
CCDC126 coiled-coil domain containing 126 -3.10155
TMEM57 transmembrane protein 57 -2.80761
CEP68 centrosomal protein 68kDa -2.77148
ELMO2 engulfment and cell motility 2 -2.63253
ANKDD1A ankyrin repeat and death domain containing 1A -2.50691
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.48149
TMX4 thioredoxin-related transmembrane protein 4 -2.44198
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits -2.42753
ERC1 ELKS/RAB6-interacting/CAST family member 1 -2.37392
LOC100507443 uncharacterized LOC100507443 -2.34504
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase -2.28843
LINC00339 long intergenic non-protein coding RNA 339 -2.27256
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 -2.2583
SLC26A10 solute carrier family 26, member 10 -2.23763
PRSS21 protease, serine, 21 (testisin) -2.18803
MTMR9 myotubularin related protein 9 -2.18581
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 -2.18131
RNF103 ring finger protein 103 -2.17824
CH25H cholesterol 25-hydroxylase -2.15967
DCST1 DC-STAMP domain containing 1 -2.15046
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -2.13169
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -2.12496
CERCAM cerebral endothelial cell adhesion molecule -2.10221
SNORD8 small nucleolar RNA, C/D box 8 -2.09975
ZNF136 zinc finger protein 136 -2.03482
LONRF1 LON peptidase N-terminal domain and ring finger 1 -2.02937
TSPEAR-AS2 TSPEAR antisense RNA 2 -2.02427
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -1.98924
FAM90A1 family with sequence similarity 90, member A1 -1.96205
SOS1 son of sevenless homolog 1 (Drosophila) -1.94215
LOC100287015 uncharacterized LOC100287015 -1.93675
LOC100422737 uncharacterized LOC100422737 -1.93446
ZNF250 zinc finger protein 250 -1.92653
RNF216 ring finger protein 216 -1.87744
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -1.8606
GID4 GID complex subunit 4 -1.85484
ERICH1 glutamate-rich 1 -1.85411
MEP1A meprin A, alpha (PABA peptide hydrolase) -1.83534
ZNF383 zinc finger protein 383 -1.81246
TUBGCP5 tubulin, gamma complex associated protein 5 -1.80499
TRIQK triple QxxK/R motif containing -1.79829
ZNF567 zinc finger protein 567 -1.79661
TUBA1A tubulin, alpha 1a -1.79476
NRG3 neuregulin 3 -1.79278
USF1 upstream transcription factor 1 -1.79078
NCOA6 nuclear receptor coactivator 6 -1.78674
KLF13 Kruppel-like factor 13 -1.74771
HKR1 HKR1, GLI-Kruppel zinc finger family member -1.74618
EVL Enah/Vasp-like -1.73702
LOC100506679 uncharacterized LOC100506679 -1.73472
ZNF44 zinc finger protein 44 -1.73379
KIDINS220 kinase D-interacting substrate, 220kDa -1.73144
S100G S100 calcium binding protein G -1.73138
ADAM2 ADAM metallopeptidase domain 2 -1.70324
LINC00337 long intergenic non-protein coding RNA 337 -1.69529
ZNF805 zinc finger protein 805 -1.68884
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase -1.67936
LINC01587 long intergenic non-protein coding RNA 1587 -1.67759
NTNG2 netrin G2 -1.67277
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide -1.67262
ASB12 ankyrin repeat and SOCS box containing 12 -1.66894
C20ORF166-AS1 C20orf166 antisense RNA 1 -1.64803
ZNF775 zinc finger protein 775 -1.64307
MAN2A2 mannosidase, alpha, class 2A, member 2 -1.63634
SCAPER S-phase cyclin A-associated protein in the ER -1.63165
AK9 adenylate kinase 9 -1.63087
OR4N4 olfactory receptor, family 4, subfamily N, member 4 -1.62295
FAM13A-AS1 FAM13A antisense RNA 1 -1.62123
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 -1.61576
FAM182B family with sequence similarity 182, member B -1.61539
KANK1 KN motif and ankyrin repeat domains 1 -1.6123
TDRD7 tudor domain containing 7 -1.61067
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 -1.60745
PDLIM3 PDZ and LIM domain 3 -1.60608
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 -1.59709
IFNAR2 interferon (alpha, beta and omega) receptor 2 -1.59449
AAMDC adipogenesis associated, Mth938 domain containing -1.58993
SRPK2 SRSF protein kinase 2 -1.58681
GAMT guanidinoacetate N-methyltransferase -1.58115
CCDC79 coiled-coil domain containing 79 -1.57975
KIAA0825 KIAA0825 -1.5789
TCEAL7 transcription elongation factor A (SII)-like 7 -1.57694
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 -1.57306
UBA6 ubiquitin-like modifier activating enzyme 6 -1.56739
RFX7 regulatory factor X, 7 -1.56326
ATP11C ATPase, class VI, type 11C -1.5603
LRRC3 leucine rich repeat containing 3 -1.55725
FAM219A family with sequence similarity 219, member A -1.55179
LOC339352 cytosolic thiouridylase subunit 1 homolog (S. pombe) pseudogene -1.55046
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase -1.5495
SESN1 sestrin 1 -1.54492
ENTHD2 ENTH domain containing 2 -1.54358
CD40LG CD40 ligand -1.54315
FAM99B family with sequence similarity 99, member B (non-protein coding) -1.54205
GSTA4 glutathione S-transferase alpha 4 -1.54129
SLX4 SLX4 structure-specific endonuclease subunit -1.53267
CLEC2L C-type lectin domain family 2, member L -1.52923
NRG2 neuregulin 2 -1.52278
ZNF680 zinc finger protein 680 -1.5191
MYBPC3 myosin binding protein C, cardiac -1.51824
LOC388780 uncharacterized LOC388780 -1.51814
INHBC inhibin, beta C -1.51481
TRAPPC10 trafficking protein particle complex 10 -1.51022
IL10RB interleukin 10 receptor, beta -1.50882
P4HA3 prolyl 4-hydroxylase, alpha polypeptide III -1.50562
LDHB lactate dehydrogenase B -1.50387
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa -1.50021
LINC00294 long intergenic non-protein coding RNA 294 -1.49912
MANEA mannosidase, endo-alpha -1.49634
KANSL1-AS1 KANSL1 antisense RNA 1 -1.49468
OR8B2 olfactory receptor, family 8, subfamily B, member 2 -1.48631
GBX2 gastrulation brain homeobox 2 -1.48169
BTG4 B-cell translocation gene 4 -1.48132
ERI1 exoribonuclease 1 -1.47746
LOC100130452 uncharacterized LOC100130452 -1.47244
KATNAL1 katanin p60 subunit A-like 1 -1.46774
MPP1 membrane protein, palmitoylated 1, 55kDa -1.46646
RP2 retinitis pigmentosa 2 (X-linked recessive) -1.4632
KIAA0355 KIAA0355 -1.46162
CAMSAP1 calmodulin regulated spectrin-associated protein 1 -1.45656
ICK intestinal cell (MAK-like) kinase -1.45479