| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | methylcrotonoyl-CoA carboxylase 1 (alpha)|This gene encodes the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 56922) |
| External Link | https://ncbi.nlm.nih.gov/gene/56922 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the MCCC1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EIF5A | eukaryotic translation initiation factor 5A | 0.0143602 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0140122 |
| GPX1 | glutathione peroxidase 1 | 0.0129783 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0120912 |
| KRT7 | keratin 7, type II | 0.0120902 |
| TSPO | translocator protein (18kDa) | 0.0112925 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.0112233 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0112072 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0111734 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.0108342 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.0106481 |
| LUM | lumican | 0.00988071 |
| S100P | S100 calcium binding protein P | 0.00987035 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00982814 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00973704 |
| PIP | prolactin-induced protein | 0.00972581 |
| FBN2 | fibrillin 2 | 0.00972323 |
| MYBPC1 | myosin binding protein C, slow type | 0.00962177 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00961752 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0094811 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00938896 |
| WBP5 | WW domain binding protein 5 | 0.00920599 |
| MEF2C | myocyte enhancer factor 2C | 0.00901795 |
| MSMB | microseminoprotein, beta- | 0.00893049 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00889497 |
| SIX1 | SIX homeobox 1 | 0.00875591 |
| FST | follistatin | 0.00870945 |
| FBXW12 | F-box and WD repeat domain containing 12 | 0.00861906 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00861453 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00838182 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.00813983 |
| ZNF589 | zinc finger protein 589 | 0.00804514 |
| RNF167 | ring finger protein 167 | 0.00795748 |
| CYB5R2 | cytochrome b5 reductase 2 | 0.00794453 |
| SIK1 | salt-inducible kinase 1 | 0.00792096 |
| PTN | pleiotrophin | 0.00776531 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00766238 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | 0.00765567 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00760289 |
| PRR11 | proline rich 11 | 0.00757419 |
| COL9A2 | collagen, type IX, alpha 2 | 0.00749986 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00746006 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00743915 |
| GOLGA8A | golgin A8 family, member A | 0.00743465 |
| ZNF160 | zinc finger protein 160 | 0.0073628 |
| CHMP4A | charged multivesicular body protein 4A | 0.00735717 |
| AGR2 | anterior gradient 2 | 0.00731828 |
| ZNF721 | zinc finger protein 721 | 0.00718744 |
| LOXL2 | lysyl oxidase-like 2 | 0.00716885 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00715654 |
| KRT17 | keratin 17, type I | 0.00714219 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00712869 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.00711625 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00708944 |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.00707091 |
| RTN2 | reticulon 2 | 0.00704682 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00703983 |
| TMEM243 | transmembrane protein 243, mitochondrial | 0.00703182 |
| TPM2 | tropomyosin 2 (beta) | 0.0070213 |
| IFRD2 | interferon-related developmental regulator 2 | 0.00695902 |
| SCAND1 | SCAN domain containing 1 | 0.00693106 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 0.00691827 |
| NOTCH2NL | notch 2 N-terminal like | 0.00691226 |
| ALOX15B | arachidonate 15-lipoxygenase, type B | 0.00686902 |
| CNTN1 | contactin 1 | 0.0068398 |
| GAS1 | growth arrest-specific 1 | 0.00683033 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.00678767 |
| NDUFS7 | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 0.00671888 |
| ABHD17A | abhydrolase domain containing 17A | 0.0066186 |
| MRPL23 | mitochondrial ribosomal protein L23 | 0.00660197 |
| ZNF91 | zinc finger protein 91 | 0.00659037 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00657519 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 0.00657306 |
| PCNA | proliferating cell nuclear antigen | 0.00656128 |
| BANF1 | barrier to autointegration factor 1 | 0.00647275 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.00646402 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 0.0063925 |
| NKTR | natural killer cell triggering receptor | 0.00629842 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0062522 |
| AK1 | adenylate kinase 1 | 0.00624137 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00622333 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.00620841 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00618736 |
| NRIP3 | nuclear receptor interacting protein 3 | 0.0061681 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00616026 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | 0.00611063 |
| PCDH9 | protocadherin 9 | 0.00608181 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.00606865 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | 0.00606366 |
| PLD3 | phospholipase D family, member 3 | 0.00605917 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.0060478 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00604275 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.00603661 |
| FOXC1 | forkhead box C1 | 0.0060347 |
| TNNI2 | troponin I type 2 (skeletal, fast) | 0.006024 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00601731 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.00601136 |
| TMEM45A | transmembrane protein 45A | 0.00600826 |
| ARPC5L | actin related protein 2/3 complex, subunit 5-like | 0.00598959 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | 0.00598479 |
| NUDC | nudC nuclear distribution protein | 0.00596036 |
| HSPA14 | heat shock 70kDa protein 14 | 0.0059418 |
| NUTF2 | nuclear transport factor 2 | 0.00592585 |
| MRPL28 | mitochondrial ribosomal protein L28 | 0.0059234 |
| POPDC3 | popeye domain containing 3 | 0.00592221 |
| BPIFA1 | BPI fold containing family A, member 1 | 0.00590581 |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) | 0.00589934 |
| POLR2E | polymerase (RNA) II (DNA directed) polypeptide E, 25kDa | 0.00589103 |
| DACH1 | dachshund family transcription factor 1 | 0.00587172 |
| GPX4 | glutathione peroxidase 4 | 0.00586908 |
| MCM7 | minichromosome maintenance complex component 7 | 0.00586409 |
| PRKCZ | protein kinase C, zeta | 0.00585704 |
| STIP1 | stress-induced phosphoprotein 1 | 0.00585299 |
| CFAP298 | cilia and flagella associated protein 298 | 0.00583339 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00583117 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa | 0.00579792 |
| GATA2 | GATA binding protein 2 | 0.00578774 |
| BBX | bobby sox homolog (Drosophila) | 0.00575686 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00575491 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 0.00574269 |
| MYDGF | myeloid-derived growth factor | 0.00573892 |
| EIF3G | eukaryotic translation initiation factor 3, subunit G | 0.00573548 |
| ATG4B | autophagy related 4B, cysteine peptidase | 0.0057332 |
| PCBP4 | poly(rC) binding protein 4 | 0.00570232 |
| PXDN | peroxidasin | 0.00569834 |
| TNS3 | tensin 3 | 0.00568708 |
| EDF1 | endothelial differentiation-related factor 1 | 0.00563225 |
| FUS | FUS RNA binding protein | 0.00562327 |
| CXORF40B | chromosome X open reading frame 40B | 0.00560854 |
| PKM | pyruvate kinase, muscle | 0.00559665 |
| TNNC2 | troponin C type 2 (fast) | 0.00558648 |
| DGKZ | diacylglycerol kinase, zeta | 0.0055755 |
| COPE | coatomer protein complex, subunit epsilon | 0.00557525 |
| CGA | glycoprotein hormones, alpha polypeptide | 0.00554999 |
| MMP1 | matrix metallopeptidase 1 | 0.00554798 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00550037 |
| COL2A1 | collagen, type II, alpha 1 | 0.00549829 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.00549341 |
| CP | ceruloplasmin (ferroxidase) | 0.00548919 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00548146 |
| APOC1 | apolipoprotein C-I | 0.00547851 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.00547817 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00546413 |
| CCNF | cyclin F | 0.00541495 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0053959 |
| SH2B2 | SH2B adaptor protein 2 | 0.005374 |
| HELLS | helicase, lymphoid-specific | 0.00537213 |
| ACP2 | acid phosphatase 2, lysosomal | 0.00536586 |
| NKX3-1 | NK3 homeobox 1 | 0.00536244 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.00535464 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.00534741 |
| COL1A2 | collagen, type I, alpha 2 | 0.00534606 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0053401 |
| KLHDC3 | kelch domain containing 3 | 0.00532221 |
| CXORF40A | chromosome X open reading frame 40A | 0.00531502 |
| TSPAN4 | tetraspanin 4 | 0.00530247 |
| COL16A1 | collagen, type XVI, alpha 1 | 0.00529612 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | 0.00528837 |
| NEFH | neurofilament, heavy polypeptide | 0.00528061 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | 0.00527152 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 0.0052583 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) | 0.00525752 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.00524597 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 0.00524441 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.0052372 |
| GPC4 | glypican 4 | 0.00522882 |
| UBE2M | ubiquitin-conjugating enzyme E2M | 0.00522551 |
| FPGS | folylpolyglutamate synthase | 0.0052023 |
| CYB561D2 | cytochrome b561 family, member D2 | 0.0051848 |
| TPBG | trophoblast glycoprotein | 0.00518375 |
| PSCA | prostate stem cell antigen | 0.00517521 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00516469 |
| PFDN6 | prefoldin subunit 6 | 0.00515442 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.00515311 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00514967 |
| TESC | tescalcin | 0.00514754 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.00514252 |
| ZNF611 | zinc finger protein 611 | 0.00513304 |
| JUNB | jun B proto-oncogene | 0.00513147 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | 0.00512982 |
| TAOK1 | TAO kinase 1 | 0.00512391 |
| CTSS | cathepsin S | 0.00511674 |
| CKM | creatine kinase, muscle | 0.00511643 |
| CCNO | cyclin O | 0.00511055 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.00508719 |
| LTF | lactotransferrin | 0.00507526 |
| RPL10 | ribosomal protein L10 | 0.00506879 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.00506355 |
| KIAA0930 | KIAA0930 | 0.00506048 |
| DSE | dermatan sulfate epimerase | 0.00505715 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.00504433 |
| DDRGK1 | DDRGK domain containing 1 | 0.00503319 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 0.00502389 |
| CRLF1 | cytokine receptor-like factor 1 | 0.00501065 |
| CD81 | CD81 molecule | 0.00501017 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.00499645 |
| ORC6 | origin recognition complex, subunit 6 | 0.00499076 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.00498976 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.00498826 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00498295 |
| NPY | neuropeptide Y | 0.00498027 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 | 0.0049594 |
| FBXO2 | F-box protein 2 | 0.00495809 |
| PROM1 | prominin 1 | 0.00494309 |
| ACD | adrenocortical dysplasia homolog (mouse) | 0.00493806 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00493789 |
| ELN | elastin | 0.00493513 |
| LRRC17 | leucine rich repeat containing 17 | 0.00493191 |
| CRYM | crystallin, mu | 0.00492387 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | 0.00492229 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | 0.00490446 |
| RIN2 | Ras and Rab interactor 2 | 0.00489547 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.00489228 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0048908 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa | 0.0048802 |
| CES1 | carboxylesterase 1 | 0.00487114 |
| BUD23 | BUD23 rRNA methyltransferase and ribosome maturation factor | 0.00486133 |
| ORM1 | orosomucoid 1 | 0.0048602 |
| ARL6IP4 | ADP-ribosylation factor-like 6 interacting protein 4 | 0.00485393 |
| ITPA | inosine triphosphatase (nucleoside triphosphate pyrophosphatase) | 0.00484666 |
| DTYMK | deoxythymidylate kinase (thymidylate kinase) | 0.00484217 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) | 0.00484203 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | 0.00482734 |
| HMGB3 | high mobility group box 3 | 0.00482543 |
| URM1 | ubiquitin related modifier 1 | 0.00482329 |
| HMGA1 | high mobility group AT-hook 1 | 0.0048156 |
| RAB13 | RAB13, member RAS oncogene family | 0.00481307 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | 0.0048061 |
| BMP2 | bone morphogenetic protein 2 | 0.00479754 |
| BDNF | brain-derived neurotrophic factor | 0.00479577 |
| ENO3 | enolase 3 (beta, muscle) | 0.0047888 |
| PRPF19 | pre-mRNA processing factor 19 | 0.00478787 |
| KYNU | kynureninase | 0.00478566 |
| SLITRK5 | SLIT and NTRK-like family, member 5 | 0.00478294 |
| NELFB | negative elongation factor complex member B | 0.00477951 |
| COL8A2 | collagen, type VIII, alpha 2 | 0.00477644 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 | 0.00477387 |
| BGN | biglycan | 0.00477125 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.00476808 |
| SAA4 | serum amyloid A4, constitutive | 0.00476574 |
| CFB | complement factor B | 0.00475488 |
| CCN2 | cellular communication network factor 2 | 0.00475202 |
| CENPBD1P1 | CENPB DNA-binding domains containing 1 pseudogene 1 | 0.00474296 |
| GPSM2 | G-protein signaling modulator 2 | 0.00473851 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.00473643 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00473458 |
| CCP110 | centriolar coiled coil protein 110kDa | 0.00472116 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.00471915 |
| SERHL2 | serine hydrolase-like 2 | 0.00471163 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.00469 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.017157 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.0139327 |
| CD93 | CD93 molecule | -0.01325 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0128691 |
| ABHD4 | abhydrolase domain containing 4 | -0.0126659 |
| S100A10 | S100 calcium binding protein A10 | -0.0126339 |
| AOC1 | amine oxidase, copper containing 1 | -0.0125935 |
| PRAME | preferentially expressed antigen in melanoma | -0.011678 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0116152 |
| HSPA2 | heat shock 70kDa protein 2 | -0.0110909 |
| GATA6 | GATA binding protein 6 | -0.0107154 |
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | -0.0104341 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -0.00981882 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | -0.00974146 |
| CD99 | CD99 molecule | -0.00956862 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00949204 |
| ANK2 | ankyrin 2, neuronal | -0.00941786 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -0.00940702 |
| SELENBP1 | selenium binding protein 1 | -0.00939958 |
| TMEM176B | transmembrane protein 176B | -0.00938446 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00928365 |
| REG3A | regenerating islet-derived 3 alpha | -0.00923087 |
| EMX2 | empty spiracles homeobox 2 | -0.00920625 |
| RGCC | regulator of cell cycle | -0.00918939 |
| CST1 | cystatin SN | -0.00918384 |
| GALC | galactosylceramidase | -0.00899593 |
| GIMAP6 | GTPase, IMAP family member 6 | -0.0089595 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.00892832 |
| CD69 | CD69 molecule | -0.00870119 |
| TSPAN7 | tetraspanin 7 | -0.00867038 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | -0.00864096 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00861635 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00860353 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.00852738 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00841367 |
| ASS1 | argininosuccinate synthase 1 | -0.00840893 |
| MEN1 | multiple endocrine neoplasia I | -0.00837488 |
| HOXB7 | homeobox B7 | -0.00836691 |
| CD200 | CD200 molecule | -0.00835016 |
| MSX1 | msh homeobox 1 | -0.00822468 |
| HOXC6 | homeobox C6 | -0.00817446 |
| ACKR3 | atypical chemokine receptor 3 | -0.00806975 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.0080687 |
| RASA4 | RAS p21 protein activator 4 | -0.00803615 |
| REG1A | regenerating islet-derived 1 alpha | -0.00791725 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00791307 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00785604 |
| NELL2 | NEL-like 2 (chicken) | -0.00784758 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00784635 |
| GPR183 | G protein-coupled receptor 183 | -0.00779113 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | -0.0077902 |
| FCGBP | Fc fragment of IgG binding protein | -0.0077695 |
| MFAP5 | microfibrillar associated protein 5 | -0.00772285 |
| CA12 | carbonic anhydrase XII | -0.00772025 |
| CCR7 | chemokine (C-C motif) receptor 7 | -0.00771345 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00768445 |
| DSP | desmoplakin | -0.00765554 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00764819 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00764671 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0076184 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00761454 |
| GAB2 | GRB2-associated binding protein 2 | -0.00757231 |
| LASP1 | LIM and SH3 protein 1 | -0.00754371 |
| TAOK3 | TAO kinase 3 | -0.00741627 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.00741154 |
| ZNF165 | zinc finger protein 165 | -0.00740432 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.00734158 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.00729529 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00728574 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00724319 |
| TMEM176A | transmembrane protein 176A | -0.00723689 |
| S1PR1 | sphingosine-1-phosphate receptor 1 | -0.00714143 |
| TLR4 | toll-like receptor 4 | -0.00712433 |
| GPR18 | G protein-coupled receptor 18 | -0.00712006 |
| AK4 | adenylate kinase 4 | -0.0070653 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00706366 |
| RCAN1 | regulator of calcineurin 1 | -0.00704419 |
| FYB1 | FYN binding protein 1 | -0.00700451 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00696305 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.00692294 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00692159 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.00690159 |
| SPRR1B | small proline-rich protein 1B | -0.00685531 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | -0.00684891 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.0067937 |
| OPN3 | opsin 3 | -0.00675519 |
| DIO1 | deiodinase, iodothyronine, type I | -0.00675426 |
| GNAS | GNAS complex locus | -0.00674782 |
| MATN2 | matrilin 2 | -0.00669805 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00669754 |
| ALDOB | aldolase B, fructose-bisphosphate | -0.00668083 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.00666721 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00666422 |
| C14ORF132 | chromosome 14 open reading frame 132 | -0.00665097 |
| HEPH | hephaestin | -0.00662376 |
| EPCAM | epithelial cell adhesion molecule | -0.00661769 |
| KRT1 | keratin 1, type II | -0.00660971 |
| CYTIP | cytohesin 1 interacting protein | -0.00660574 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00659179 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00657939 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.00657364 |
| CNR1 | cannabinoid receptor 1 (brain) | -0.00656858 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) | -0.00656457 |
| STON1 | stonin 1 | -0.00654232 |
| WT1 | Wilms tumor 1 | -0.00649899 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00648579 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00648531 |
| THBD | thrombomodulin | -0.00648172 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00647106 |
| MAL | mal, T-cell differentiation protein | -0.00644321 |
| IFI44L | interferon-induced protein 44-like | -0.00641706 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00640085 |
| CD96 | CD96 molecule | -0.00636712 |
| GPR65 | G protein-coupled receptor 65 | -0.00635729 |
| DENND1B | DENN/MADD domain containing 1B | -0.00635259 |
| MYO1D | myosin ID | -0.00634773 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.00634112 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.00633296 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00629208 |
| BMP7 | bone morphogenetic protein 7 | -0.00625056 |
| GCH1 | GTP cyclohydrolase 1 | -0.00620432 |
| ZNF83 | zinc finger protein 83 | -0.00619428 |
| CLTB | clathrin, light chain B | -0.00619107 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -0.00618265 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | -0.00617007 |
| NOX4 | NADPH oxidase 4 | -0.00615995 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent | -0.00614863 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 | -0.00614817 |
| CLIC5 | chloride intracellular channel 5 | -0.00613899 |
| ACE2 | angiotensin I converting enzyme 2 | -0.00612765 |
| CFI | complement factor I | -0.00612686 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | -0.00612499 |
| ADM | adrenomedullin | -0.00611945 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00611515 |
| TP53I3 | tumor protein p53 inducible protein 3 | -0.00611397 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.00610585 |
| CD27 | CD27 molecule | -0.00610545 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | -0.0060977 |
| SORD | sorbitol dehydrogenase | -0.00607283 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | -0.00606964 |
| WSB2 | WD repeat and SOCS box containing 2 | -0.00605948 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00605559 |
| MAOA | monoamine oxidase A | -0.00599796 |
| NELL1 | NEL-like 1 (chicken) | -0.00597241 |
| IL1R2 | interleukin 1 receptor, type II | -0.0059564 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00592686 |
| SLC12A1 | solute carrier family 12 (sodium/potassium/chloride transporter), member 1 | -0.00592204 |
| H1-2 | H1.2 linker histone, cluster member | -0.00590563 |
| MX1 | MX dynamin-like GTPase 1 | -0.00590314 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00589184 |
| SI | sucrase-isomaltase (alpha-glucosidase) | -0.00588527 |
| COL4A2 | collagen, type IV, alpha 2 | -0.00588077 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00586669 |
| THSD7A | thrombospondin, type I, domain containing 7A | -0.00586257 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00582619 |
| SERINC5 | serine incorporator 5 | -0.00582348 |
| TBXA2R | thromboxane A2 receptor | -0.00580945 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | -0.00580757 |
| STK17A | serine/threonine kinase 17a | -0.00580183 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | -0.00576476 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.00575796 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | -0.00575671 |
| RIMS3 | regulating synaptic membrane exocytosis 3 | -0.00575034 |
| GCG | glucagon | -0.00574831 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00574644 |
| ZNF107 | zinc finger protein 107 | -0.0057365 |
| IFI44 | interferon-induced protein 44 | -0.00572229 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 | -0.00572111 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0057137 |
| NDRG1 | N-myc downstream regulated 1 | -0.00570228 |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 | -0.00570163 |
| MALL | mal, T-cell differentiation protein-like | -0.00565768 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00564881 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.00564827 |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 | -0.00563113 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00562729 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.00562715 |
| CLEC2D | C-type lectin domain family 2, member D | -0.00561028 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.00560694 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.00560561 |
| SUMO3 | small ubiquitin-like modifier 3 | -0.00560093 |
| PNMA1 | paraneoplastic Ma antigen 1 | -0.00560045 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.00560016 |
| E2F2 | E2F transcription factor 2 | -0.00559779 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00559467 |
| RGS5 | regulator of G-protein signaling 5 | -0.00558919 |
| ARG2 | arginase 2 | -0.00558721 |
| PPAP2A | phosphatidic acid phosphatase type 2A | -0.00558718 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) | -0.00558056 |
| SPOP | speckle-type POZ protein | -0.00557955 |
| LEFTY1 | left-right determination factor 1 | -0.00557209 |
| CDHR5 | cadherin-related family member 5 | -0.00556862 |
| ZNF467 | zinc finger protein 467 | -0.0055683 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.00555849 |
| RAB25 | RAB25, member RAS oncogene family | -0.00555401 |
| RSF1 | remodeling and spacing factor 1 | -0.0055375 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | -0.00553581 |
| CALML4 | calmodulin-like 4 | -0.0055282 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.00551159 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00550872 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00550364 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.00549983 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.0054961 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | -0.00549106 |
| PRKCA | protein kinase C, alpha | -0.00548837 |
| CA4 | carbonic anhydrase IV | -0.00548737 |
| RTN1 | reticulon 1 | -0.00548341 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00547845 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | -0.00547624 |
| VLDLR | very low density lipoprotein receptor | -0.00546203 |
| RTN4 | reticulon 4 | -0.00546174 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.00544736 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | -0.00544486 |
| RGS10 | regulator of G-protein signaling 10 | -0.00543315 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.00542953 |
| KLK10 | kallikrein-related peptidase 10 | -0.00542364 |
| KIFAP3 | kinesin-associated protein 3 | -0.00540054 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | -0.00538723 |
| FKBP5 | FK506 binding protein 5 | -0.00536342 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | -0.00535724 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.00535036 |
| BPGM | 2,3-bisphosphoglycerate mutase | -0.00533612 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00533265 |
| RTP4 | receptor (chemosensory) transporter protein 4 | -0.00533242 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | -0.00532363 |
| GIMAP4 | GTPase, IMAP family member 4 | -0.00530669 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00530439 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.00529201 |
| ACLY | ATP citrate lyase | -0.00528835 |
| FGF9 | fibroblast growth factor 9 | -0.00528729 |
| ANGPT2 | angiopoietin 2 | -0.00523697 |
| CEP68 | centrosomal protein 68kDa | -0.00523232 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.00523212 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -0.00523013 |
| INHBB | inhibin, beta B | -0.00522431 |
| FABP1 | fatty acid binding protein 1, liver | -0.0052024 |
| HLTF | helicase-like transcription factor | -0.00519742 |
| KIAA0226L | KIAA0226-like | -0.00519332 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.00519072 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | -0.00518816 |
| UBE3B | ubiquitin protein ligase E3B | -0.00518644 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | -0.00518513 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00518047 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 | -0.00517649 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -0.00517461 |
| TRAT1 | T cell receptor associated transmembrane adaptor 1 | -0.00517413 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00517136 |
| MARCH8 | membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase | -0.00517095 |
| ADD3 | adducin 3 (gamma) | -0.00514503 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.00513581 |
