| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | methylcrotonoyl-CoA carboxylase 2 (beta)|This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 64087) |
| External Link | https://ncbi.nlm.nih.gov/gene/64087 |
| Similar Terms | |
| Downloads & Tools |
497 genes differentially expressed following the MCCC2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPX2 | glutathione peroxidase 2 | 0.0128889 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0118671 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.01142 |
| LAMB1 | laminin, beta 1 | 0.0107316 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0106981 |
| CALB1 | calbindin 1, 28kDa | 0.0104593 |
| NRCAM | neuronal cell adhesion molecule | 0.0103313 |
| E2F2 | E2F transcription factor 2 | 0.0103171 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.0101991 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.0100872 |
| KRT20 | keratin 20, type I | 0.00981702 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00966012 |
| GAB2 | GRB2-associated binding protein 2 | 0.00954903 |
| RTN2 | reticulon 2 | 0.0095011 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00948811 |
| CHGB | chromogranin B | 0.00917413 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00915547 |
| RGS5 | regulator of G-protein signaling 5 | 0.00914899 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.00887917 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00880556 |
| MELK | maternal embryonic leucine zipper kinase | 0.00869646 |
| SRPX | sushi-repeat containing protein, X-linked | 0.0086248 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00856992 |
| MEN1 | multiple endocrine neoplasia I | 0.00855335 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.00850935 |
| VLDLR | very low density lipoprotein receptor | 0.00846801 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.00836777 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00835871 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00835849 |
| ANK2 | ankyrin 2, neuronal | 0.00831117 |
| NFASC | neurofascin | 0.00814053 |
| DES | desmin | 0.00808517 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.00806902 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00805717 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.00803157 |
| PFKM | phosphofructokinase, muscle | 0.00799066 |
| MATN2 | matrilin 2 | 0.00791956 |
| MAL | mal, T-cell differentiation protein | 0.00780242 |
| SVIL | supervillin | 0.00775976 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00762106 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00759278 |
| PLK1 | polo-like kinase 1 | 0.00751474 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00746646 |
| TPM2 | tropomyosin 2 (beta) | 0.00743162 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00742475 |
| DLD | dihydrolipoamide dehydrogenase | 0.00738211 |
| TNNC1 | troponin C type 1 (slow) | 0.00722066 |
| POSTN | periostin, osteoblast specific factor | 0.00712074 |
| KLHL41 | kelch-like family member 41 | 0.00702647 |
| PEG10 | paternally expressed 10 | 0.00701721 |
| CA12 | carbonic anhydrase XII | 0.00699657 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.00699439 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | 0.00698353 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00697214 |
| FZD5 | frizzled class receptor 5 | 0.00695203 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00694177 |
| SCRIB | scribbled planar cell polarity protein | 0.00691921 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.00691902 |
| KLK11 | kallikrein-related peptidase 11 | 0.00686281 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 | 0.00684369 |
| TESC | tescalcin | 0.00683394 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | 0.00679907 |
| ASPH | aspartate beta-hydroxylase | 0.00675223 |
| TSPAN7 | tetraspanin 7 | 0.00674137 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.00672828 |
| RHOBTB1 | Rho-related BTB domain containing 1 | 0.00668923 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00668807 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.00667391 |
| PLN | phospholamban | 0.00659691 |
| DZIP1 | DAZ interacting zinc finger protein 1 | 0.00658432 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.00647479 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00647474 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.00646941 |
| APOD | apolipoprotein D | 0.00645764 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00645554 |
| CS | citrate synthase | 0.0064282 |
| CHGA | chromogranin A | 0.00642558 |
| PDE10A | phosphodiesterase 10A | 0.00641904 |
| RCAN1 | regulator of calcineurin 1 | 0.00641335 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00639894 |
| DMPK | dystrophia myotonica-protein kinase | 0.00634117 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00633621 |
| CALCA | calcitonin-related polypeptide alpha | 0.00630742 |
| TYRP1 | tyrosinase-related protein 1 | 0.00625875 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.00625529 |
| JAG2 | jagged 2 | 0.00624625 |
| CCN2 | cellular communication network factor 2 | 0.0062413 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.00623901 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00623895 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | 0.00623566 |
| PNMA2 | paraneoplastic Ma antigen 2 | 0.00623329 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.006227 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.00620879 |
| TLE4 | transducin-like enhancer of split 4 | 0.00620126 |
| B4GALT6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | 0.00617886 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.0061619 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00614989 |
| CYB561 | cytochrome b561 | 0.00612204 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 0.00611593 |
| FERMT1 | fermitin family member 1 | 0.00610992 |
| MLXIP | MLX interacting protein | 0.00610147 |
| MTCL1 | microtubule crosslinking factor 1 | 0.00608603 |
| CKM | creatine kinase, muscle | 0.00607436 |
| SULF1 | sulfatase 1 | 0.00606746 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0060645 |
| PITRM1 | pitrilysin metallopeptidase 1 | 0.00605668 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00605057 |
| PCDH9 | protocadherin 9 | 0.00603803 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00601663 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00601188 |
| SCG5 | secretogranin V | 0.00597715 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.00597429 |
| SST | somatostatin | 0.00597401 |
| NID2 | nidogen 2 (osteonidogen) | 0.00594714 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.00592282 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.00589639 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.00586882 |
| SUCLA2 | succinate-CoA ligase, ADP-forming, beta subunit | 0.00586622 |
| TSPAN8 | tetraspanin 8 | 0.00586312 |
| TBC1D31 | TBC1 domain family, member 31 | 0.00583396 |
| ATP10B | ATPase, class V, type 10B | 0.0058147 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.0058111 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00580442 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | 0.00580124 |
| COL4A6 | collagen, type IV, alpha 6 | 0.00579501 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | 0.00578621 |
| PFKP | phosphofructokinase, platelet | 0.00578142 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | 0.00577852 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | 0.00576045 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0057501 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | 0.00574403 |
| NEFM | neurofilament, medium polypeptide | 0.00572548 |
| GTPBP4 | GTP binding protein 4 | 0.00572527 |
| AEBP1 | AE binding protein 1 | 0.00571655 |
| MMP12 | matrix metallopeptidase 12 | 0.00571462 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.00570779 |
| PLP1 | proteolipid protein 1 | 0.0057028 |
| MCAM | melanoma cell adhesion molecule | 0.00567694 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00565472 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00564747 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.00563577 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 0.00563098 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00562823 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00562345 |
| CNTN1 | contactin 1 | 0.00560341 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 0.0055984 |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa | 0.00559488 |
| NOTCH3 | notch 3 | 0.00559209 |
| PYGM | phosphorylase, glycogen, muscle | 0.00557893 |
| PDLIM3 | PDZ and LIM domain 3 | 0.00556624 |
| DPEP1 | dipeptidase 1 (renal) | 0.00556227 |
| GAS1 | growth arrest-specific 1 | 0.0055498 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 0.00554942 |
| ITGA6 | integrin, alpha 6 | 0.00554407 |
| MCCC1 | methylcrotonoyl-CoA carboxylase 1 (alpha) | 0.00553627 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00553354 |
| BOP1 | block of proliferation 1 | 0.00551952 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.00550276 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | 0.00550015 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00548075 |
| TNNI2 | troponin I type 2 (skeletal, fast) | 0.00546192 |
| UBAP2 | ubiquitin associated protein 2 | 0.00545816 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.00545664 |
| ACTA1 | actin, alpha 1, skeletal muscle | 0.00542887 |
| RASA4 | RAS p21 protein activator 4 | 0.00541462 |
| OPN3 | opsin 3 | 0.00537437 |
| NRXN3 | neurexin 3 | 0.00536557 |
| STK26 | serine/threonine protein kinase 26 | 0.00536485 |
| HEPH | hephaestin | 0.00535903 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00535394 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00534233 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.00534008 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00534005 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.00533708 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 0.00531718 |
| DUOX2 | dual oxidase 2 | 0.00529695 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | 0.00529529 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.005293 |
| USH1C | Usher syndrome 1C (autosomal recessive, severe) | 0.00528558 |
| NPR3 | natriuretic peptide receptor 3 | 0.00527082 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | 0.00525463 |
| TTN | titin | 0.00524741 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 0.00522964 |
| PRKCA | protein kinase C, alpha | 0.00522714 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0052231 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0052096 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.00520841 |
| TRAK1 | trafficking protein, kinesin binding 1 | 0.00520197 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00520173 |
| YBX3 | Y box binding protein 3 | 0.0051986 |
| KLK6 | kallikrein-related peptidase 6 | 0.00517775 |
| AOC1 | amine oxidase, copper containing 1 | 0.00517391 |
| GOLGA3 | golgin A3 | 0.00517381 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.00516505 |
| XPO7 | exportin 7 | 0.00516027 |
| NDRG1 | N-myc downstream regulated 1 | 0.00515977 |
| AOC3 | amine oxidase, copper containing 3 | 0.00515873 |
| TNNI1 | troponin I type 1 (skeletal, slow) | 0.00515029 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.00514199 |
| MMP3 | matrix metallopeptidase 3 | 0.00513954 |
| EHBP1 | EH domain binding protein 1 | 0.00513736 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00513617 |
| LDB3 | LIM domain binding 3 | 0.00513469 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.00513086 |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) | 0.00512624 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.00512439 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00511562 |
| TRRAP | transformation/transcription domain-associated protein | 0.00511262 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | 0.00510665 |
| C7 | complement component 7 | 0.00510582 |
| CCDC91 | coiled-coil domain containing 91 | 0.0050991 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00509665 |
| MYOT | myotilin | 0.00509612 |
| DMD | dystrophin | 0.00508965 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.00508777 |
| PMP2 | peripheral myelin protein 2 | 0.00507425 |
| KPNB1 | karyopherin (importin) beta 1 | 0.00507296 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00506094 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.00505363 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.00504641 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00503927 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.00502792 |
| PLCB4 | phospholipase C, beta 4 | 0.00502758 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | 0.00502581 |
| EPCAM | epithelial cell adhesion molecule | 0.00502557 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | 0.00501891 |
| DDHD2 | DDHD domain containing 2 | 0.00500706 |
| DCHS1 | dachsous cadherin-related 1 | 0.00499837 |
| TAOK3 | TAO kinase 3 | 0.00499785 |
| INSM1 | insulinoma-associated 1 | 0.00499107 |
| DCK | deoxycytidine kinase | 0.00499056 |
| FABP7 | fatty acid binding protein 7, brain | 0.00496161 |
| WNT4 | wingless-type MMTV integration site family, member 4 | 0.00496064 |
| CCNB1 | cyclin B1 | 0.00495797 |
| NSG1 | neuron specific gene family member 1 | 0.00495583 |
| ACSF2 | acyl-CoA synthetase family member 2 | 0.00495511 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | 0.00494938 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.00494557 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00494361 |
| MMP1 | matrix metallopeptidase 1 | 0.00493167 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | 0.00492059 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.00491732 |
| MICU2 | mitochondrial calcium uptake 2 | 0.00491069 |
| MGP | matrix Gla protein | 0.00490103 |
| MUC13 | mucin 13, cell surface associated | 0.0048944 |
| NDRG4 | NDRG family member 4 | 0.00489141 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.00488998 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.00488909 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.00488434 |
| LHFP | lipoma HMGIC fusion partner | 0.00488014 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EIF5A | eukaryotic translation initiation factor 5A | -0.015684 |
| C4BPA | complement component 4 binding protein, alpha | -0.0145875 |
| MMP9 | matrix metallopeptidase 9 | -0.0129749 |
| KRT5 | keratin 5, type II | -0.0122222 |
| S100A9 | S100 calcium binding protein A9 | -0.0121 |
| TMSB15A | thymosin beta 15a | -0.0117892 |
| CLU | clusterin | -0.011155 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.0109639 |
| TMEM45A | transmembrane protein 45A | -0.0109022 |
| TEX10 | testis expressed 10 | -0.0107879 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0107042 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0106732 |
| CP | ceruloplasmin (ferroxidase) | -0.0103787 |
| NIBAN1 | niban apoptosis regulator 1 | -0.0103609 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.0102658 |
| CSTA | cystatin A (stefin A) | -0.0102579 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0102298 |
| LY96 | lymphocyte antigen 96 | -0.0099897 |
| TYROBP | TYRO protein tyrosine kinase binding protein | -0.00998038 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00998028 |
| RRAGD | Ras-related GTP binding D | -0.00993542 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00983612 |
| S100A10 | S100 calcium binding protein A10 | -0.00981495 |
| PIP | prolactin-induced protein | -0.00971725 |
| PLBD1 | phospholipase B domain containing 1 | -0.00965539 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | -0.00957336 |
| S100A8 | S100 calcium binding protein A8 | -0.00954248 |
| AQP9 | aquaporin 9 | -0.00949231 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | -0.00948397 |
| CYBB | cytochrome b-245, beta polypeptide | -0.00945752 |
| FGF13 | fibroblast growth factor 13 | -0.00937669 |
| CD52 | CD52 molecule | -0.00934489 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00927743 |
| CD14 | CD14 molecule | -0.00925545 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.00925227 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00901582 |
| ADIRF | adipogenesis regulatory factor | -0.00901566 |
| KRT19 | keratin 19, type I | -0.00887657 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00882035 |
| MAGEA3 | melanoma antigen family A3 | -0.00863675 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 | -0.00857721 |
| EMP3 | epithelial membrane protein 3 | -0.00822244 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | -0.00810824 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00806722 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.00805972 |
| IFI30 | interferon, gamma-inducible protein 30 | -0.00805302 |
| MAOB | monoamine oxidase B | -0.00802345 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | -0.0079956 |
| CD99 | CD99 molecule | -0.00795213 |
| TPST2 | tyrosylprotein sulfotransferase 2 | -0.00782213 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00780932 |
| CDO1 | cysteine dioxygenase type 1 | -0.00776801 |
| HIST1H2AE | histone cluster 1, H2ae | -0.00775411 |
| NPY1R | neuropeptide Y receptor Y1 | -0.0077511 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00771281 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00765574 |
| CYP2C8 | cytochrome P450, family 2, subfamily C, polypeptide 8 | -0.00761501 |
| CES1 | carboxylesterase 1 | -0.00757851 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00753347 |
| SC5D | sterol-C5-desaturase | -0.00750571 |
| ORM1 | orosomucoid 1 | -0.00747577 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00746033 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | -0.00743632 |
| GSTO1 | glutathione S-transferase omega 1 | -0.00742782 |
| TSPAN4 | tetraspanin 4 | -0.00739776 |
| GPX1 | glutathione peroxidase 1 | -0.00737256 |
| PUDP | pseudouridine 5'-phosphatase | -0.00737191 |
| CD163 | CD163 molecule | -0.00736043 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | -0.00735692 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | -0.00731541 |
| ASS1 | argininosuccinate synthase 1 | -0.00731541 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.00730669 |
| APCS | amyloid P component, serum | -0.00730503 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00728365 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00727391 |
| KRT15 | keratin 15, type I | -0.00721837 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00718377 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.00716254 |
| ITIH3 | inter-alpha-trypsin inhibitor heavy chain 3 | -0.00714759 |
| ITIH1 | inter-alpha-trypsin inhibitor heavy chain 1 | -0.00712471 |
| TPBG | trophoblast glycoprotein | -0.00712124 |
| CPB2 | carboxypeptidase B2 (plasma) | -0.00709535 |
| TRAPPC3 | trafficking protein particle complex 3 | -0.00708536 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.00705151 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00700164 |
| ACOT9 | acyl-CoA thioesterase 9 | -0.00698071 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.00693898 |
| RAB9A | RAB9A, member RAS oncogene family | -0.00690581 |
| MLPH | melanophilin | -0.0068987 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.0068899 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | -0.0068836 |
| LECT2 | leukocyte cell-derived chemotaxin 2 | -0.00687853 |
| ADH1A | alcohol dehydrogenase 1A (class I), alpha polypeptide | -0.00687451 |
| H1-2 | H1.2 linker histone, cluster member | -0.00687067 |
| HSPB11 | heat shock protein family B (small), member 11 | -0.00687008 |
| UGT2B4 | UDP glucuronosyltransferase 2 family, polypeptide B4 | -0.00685961 |
| BID | BH3 interacting domain death agonist | -0.00682987 |
| XIC | X chromosome inactivation center | -0.00682663 |
| CAPG | capping protein (actin filament), gelsolin-like | -0.00681312 |
| DUSP3 | dual specificity phosphatase 3 | -0.00678652 |
| NANS | N-acetylneuraminic acid synthase | -0.00678625 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | -0.00676626 |
| ICAM2 | intercellular adhesion molecule 2 | -0.00676605 |
| PRKCB | protein kinase C, beta | -0.00675207 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00672764 |
| SEPHS2 | selenophosphate synthetase 2 | -0.00672405 |
| MT1E | metallothionein 1E | -0.00672022 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | -0.00670615 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00667167 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00663272 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0065963 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00659521 |
| EPAS1 | endothelial PAS domain protein 1 | -0.00658492 |
| NOTCH2NL | notch 2 N-terminal like | -0.00657671 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | -0.00655716 |
| SCAND1 | SCAN domain containing 1 | -0.00646346 |
| KRT13 | keratin 13, type I | -0.00644658 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00644026 |
| C1ORF54 | chromosome 1 open reading frame 54 | -0.00642506 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00641815 |
| C1ORF115 | chromosome 1 open reading frame 115 | -0.00641627 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 | -0.00640297 |
| ATP5MG | ATP synthase membrane subunit g | -0.00640247 |
| TPSAB1 | tryptase alpha/beta 1 | -0.0063942 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00636795 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.00634361 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.00631368 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00631311 |
| TRIB3 | tribbles pseudokinase 3 | -0.00631018 |
| PON3 | paraoxonase 3 | -0.00630196 |
| SFN | stratifin | -0.00630087 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00629915 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | -0.00627651 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | -0.00627482 |
| CD9 | CD9 molecule | -0.00627012 |
| HIST1H2BH | histone cluster 1, H2bh | -0.00625439 |
| KRT17 | keratin 17, type I | -0.00625413 |
| MAT1A | methionine adenosyltransferase I, alpha | -0.00623328 |
| APMAP | adipocyte plasma membrane associated protein | -0.00622639 |
| C11ORF71 | chromosome 11 open reading frame 71 | -0.00622308 |
| SHROOM2 | shroom family member 2 | -0.00621358 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.00621112 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | -0.0062034 |
| SLC43A3 | solute carrier family 43, member 3 | -0.00620037 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00619771 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.00618977 |
| RNASE6 | ribonuclease, RNase A family, k6 | -0.00615648 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.00615084 |
| EVA1B | eva-1 homolog B (C. elegans) | -0.00614256 |
| CEP57 | centrosomal protein 57kDa | -0.0061382 |
| AHSG | alpha-2-HS-glycoprotein | -0.00613348 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | -0.00613062 |
| RHOC | ras homolog family member C | -0.00611803 |
| ACP5 | acid phosphatase 5, tartrate resistant | -0.00607122 |
| NXT2 | nuclear transport factor 2-like export factor 2 | -0.006057 |
| DSE | dermatan sulfate epimerase | -0.00605641 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 | -0.00604674 |
| TSPAN6 | tetraspanin 6 | -0.00603111 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | -0.00601634 |
| SAA4 | serum amyloid A4, constitutive | -0.00599885 |
| HPR | haptoglobin-related protein | -0.00598826 |
| NKX3-1 | NK3 homeobox 1 | -0.00597855 |
| TSPO | translocator protein (18kDa) | -0.00597245 |
| S100A2 | S100 calcium binding protein A2 | -0.00595684 |
| C2 | complement component 2 | -0.0059495 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00594199 |
| CD300A | CD300a molecule | -0.00593834 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00592705 |
| ESR1 | estrogen receptor 1 | -0.00591037 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00587247 |
| AIF1 | allograft inflammatory factor 1 | -0.00585566 |
| CYP3A7 | cytochrome P450, family 3, subfamily A, polypeptide 7 | -0.00584221 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00583534 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00581531 |
| RAB14 | RAB14, member RAS oncogene family | -0.00581184 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | -0.00580508 |
| SECTM1 | secreted and transmembrane 1 | -0.0058046 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00579943 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00579814 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.00578308 |
| BTG3 | BTG family, member 3 | -0.00575338 |
| CFHR2 | complement factor H-related 2 | -0.00574165 |
| MT1F | metallothionein 1F | -0.00574144 |
| MRPL40 | mitochondrial ribosomal protein L40 | -0.0057285 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.00571942 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00571448 |
| CD83 | CD83 molecule | -0.00568977 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0056884 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.00568771 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 | -0.00568401 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | -0.00567953 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | -0.00567641 |
| TM2D3 | TM2 domain containing 3 | -0.00567613 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | -0.00567545 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00567512 |
| CRP | C-reactive protein, pentraxin-related | -0.00566773 |
| NCF2 | neutrophil cytosolic factor 2 | -0.0056223 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | -0.00561574 |
| BBX | bobby sox homolog (Drosophila) | -0.00561551 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.00557959 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.00557228 |
| IL6R | interleukin 6 receptor | -0.00556713 |
| SAP30 | Sin3A-associated protein, 30kDa | -0.00555891 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.00555207 |
| FGL1 | fibrinogen-like 1 | -0.00554678 |
| FMO3 | flavin containing monooxygenase 3 | -0.00554064 |
| SH3BP4 | SH3-domain binding protein 4 | -0.00553972 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00553735 |
| GUK1 | guanylate kinase 1 | -0.00553186 |
| TRIM2 | tripartite motif containing 2 | -0.00553023 |
| NPC2 | Niemann-Pick disease, type C2 | -0.00548885 |
| APOC2 | apolipoprotein C-II | -0.00548644 |
| IGSF6 | immunoglobulin superfamily, member 6 | -0.00547501 |
| CD63 | CD63 molecule | -0.00547047 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 | -0.00546806 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 | -0.00546665 |
| HPX | hemopexin | -0.00546495 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | -0.00544324 |
| FDX1 | ferredoxin 1 | -0.00543911 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -0.00543623 |
| MAGEB2 | melanoma antigen family B2 | -0.00543251 |
| ANXA5 | annexin A5 | -0.00543196 |
| TLR5 | toll-like receptor 5 | -0.00542939 |
| RPL26L1 | ribosomal protein L26-like 1 | -0.00542557 |
| STC2 | stanniocalcin 2 | -0.00540772 |
| CLEC7A | C-type lectin domain family 7, member A | -0.00540094 |
| ABHD6 | abhydrolase domain containing 6 | -0.00539737 |
| BANP | BTG3 associated nuclear protein | -0.00539617 |
| PXDC1 | PX domain containing 1 | -0.00538672 |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | -0.00536949 |
| RGS10 | regulator of G-protein signaling 10 | -0.00536761 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | -0.00534907 |
| HABP2 | hyaluronan binding protein 2 | -0.00532237 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.0053153 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | -0.00530732 |
| ANGPTL3 | angiopoietin-like 3 | -0.00530622 |
| RND3 | Rho family GTPase 3 | -0.0052947 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00529251 |
| APOB | apolipoprotein B | -0.00528087 |
| PRDX4 | peroxiredoxin 4 | -0.00526123 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.00525313 |
| PLK2 | polo-like kinase 2 | -0.00525191 |
| RETREG2 | reticulophagy regulator family member 2 | -0.00524751 |
| IL2RB | interleukin 2 receptor, beta | -0.00524739 |
| PFDN5 | prefoldin subunit 5 | -0.00524427 |
| BAAT | bile acid CoA:amino acid N-acyltransferase | -0.00523977 |
| KYNU | kynureninase | -0.00523526 |
