MCF2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description MCF.2 cell line derived transforming sequence|The oncogenic protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases. Several transcript variants encoding different isoforms have been found for this gene. These isoforms exhibit different expression patterns and varying levels of GEF activity.[provided by RefSeq, Jan 2010] (NCBI Entrez Gene Database, 4168)
External Link http://www.ncbi.nlm.nih.gov/gene/4168
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Genes

29 interacting proteins for MCF2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
CDC42 cell division cycle 42
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNG2 guanine nucleotide binding protein (G protein), gamma 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RDX radixin
RHOA ras homolog family member A
RHOB ras homolog family member B
RHOBTB1 Rho-related BTB domain containing 1
RHOBTB2 Rho-related BTB domain containing 2
RHOC ras homolog family member C
RHOD ras homolog family member D
RHOF ras homolog family member F (in filopodia)
RHOG ras homolog family member G
RHOH ras homolog family member H
RHOJ ras homolog family member J
RHOQ ras homolog family member Q
RHOT1 ras homolog family member T1
RHOT2 ras homolog family member T2
RHOU ras homolog family member U
RHOV ras homolog family member V
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TNK2 tyrosine kinase, non-receptor, 2
UBC ubiquitin C