MCF7_Alendronate sodium trihydrate_10nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description Alendronate sodium trihydrate 10nM perturbation in MCF7 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the MCF7_Alendronate sodium trihydrate_10nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
TFF1 trefoil factor 1 0.229991
SYTL2 synaptotagmin-like 2 0.131114
BCAS3 breast carcinoma amplified sequence 3 0.122586
DSPP dentin sialophosphoprotein 0.109946
CTSD cathepsin D 0.109649
KRT19 keratin 19, type I 0.0935259
RPS2 ribosomal protein S2 0.0807029
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.0795367
RPS8 ribosomal protein S8 0.0772185
SMIM14 small integral membrane protein 14 0.076862
PABPC1 poly(A) binding protein, cytoplasmic 1 0.070448
IGFBP5 insulin-like growth factor binding protein 5 0.0683224
ERBB3 erb-b2 receptor tyrosine kinase 3 0.0679979
NRCAM neuronal cell adhesion molecule 0.067408
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0657773
EMP2 epithelial membrane protein 2 0.0617847
XBP1 X-box binding protein 1 0.0584371
GREB1 growth regulation by estrogen in breast cancer 1 0.0577118
RPS5 ribosomal protein S5 0.0564713
ATXN7L1 ataxin 7-like 1 0.0544216
RPS3 ribosomal protein S3 0.0543494
RPL13A ribosomal protein L13a 0.052647
CUX1 cut-like homeobox 1 0.0515345
SQLE squalene epoxidase 0.0513511
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.0509862
UBL4A ubiquitin-like 4A 0.0503991
CELF1 CUGBP, Elav-like family member 1 0.0494859
RPL37A ribosomal protein L37a 0.0492554
RPL18 ribosomal protein L18 0.0471851
GNAS GNAS complex locus 0.0465729
FDPS farnesyl diphosphate synthase 0.0457332
MTDH metadherin 0.0454394
ESR1 estrogen receptor 1 0.0451161
FTH1 ferritin, heavy polypeptide 1 0.0440137
RPL38 ribosomal protein L38 0.0435789
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.0432641
MSI2 musashi RNA-binding protein 2 0.0417541
RPL11 ribosomal protein L11 0.0414471
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.0414295
ERBB4 erb-b2 receptor tyrosine kinase 4 0.0412314
CXXC5 CXXC finger protein 5 0.0410961
EPHA4 EPH receptor A4 0.0402066
MYOF myoferlin 0.0390648
RPS21 ribosomal protein S21 0.0388952
FOXP1 forkhead box P1 0.0370471
TXNIP thioredoxin interacting protein 0.036992
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0358716
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 0.0357073
TTC3 tetratricopeptide repeat domain 3 0.0355059
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 0.0349552
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.034601
CST3 cystatin C 0.0342663
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.0341918
MAVS mitochondrial antiviral signaling protein 0.0341316
ATP5F1E ATP synthase F1 subunit epsilon 0.0340272
LDLR low density lipoprotein receptor 0.0335485
CD24 CD24 molecule 0.0333931
RPL15 ribosomal protein L15 0.0333213
ABHD12 abhydrolase domain containing 12 0.0331466
RSL24D1 ribosomal L24 domain containing 1 0.033045
NRP1 neuropilin 1 0.0328716
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.0325488
DTNA dystrobrevin, alpha 0.0321436
EIF4B eukaryotic translation initiation factor 4B 0.0319617
USP32 ubiquitin specific peptidase 32 0.0318604
RAB31 RAB31, member RAS oncogene family 0.0313872
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.0313121
MED13 mediator complex subunit 13 0.0312278
MAPKAP1 mitogen-activated protein kinase associated protein 1 0.0308354
SLC38A1 solute carrier family 38, member 1 0.030702
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.0306633
FNBP4 formin binding protein 4 0.0306614
EEF2 eukaryotic translation elongation factor 2 0.0305397
RPLP1 ribosomal protein, large, P1 0.030361
PAWR PRKC, apoptosis, WT1, regulator 0.0302366
RPL3 ribosomal protein L3 0.0298516
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 0.029796
RPL30 ribosomal protein L30 0.0297267
RPS6 ribosomal protein S6 0.0295096
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.028869
MRPL13 mitochondrial ribosomal protein L13 0.0287203
PRR14L proline rich 14-like 0.0286492
RPL23 ribosomal protein L23 0.0286213
ARMC9 armadillo repeat containing 9 0.0285617
CTNND2 catenin (cadherin-associated protein), delta 2 0.0284145
GATAD2B GATA zinc finger domain containing 2B 0.0282273
STYXL1 serine/threonine/tyrosine interacting-like 1 0.0280426
HSPB1 heat shock 27kDa protein 1 0.028015
RPL7A ribosomal protein L7a 0.0279908
BCAS1 breast carcinoma amplified sequence 1 0.0277452
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0274053
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.0273615
TMEM150C transmembrane protein 150C 0.0273569
RACK1 receptor for activated C kinase 1 0.0273462
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 0.02731
RPL12 ribosomal protein L12 0.0272232
DCDC2 doublecortin domain containing 2 0.0269118
TLK1 tousled-like kinase 1 0.0265983
RABGAP1L RAB GTPase activating protein 1-like 0.0264965
BCL2L1 BCL2-like 1 0.0264348
PAN3 PAN3 poly(A) specific ribonuclease subunit 0.0262973
PARK7 parkinson protein 7 0.0262374
MVD mevalonate (diphospho) decarboxylase 0.0261748
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0260032
PANK3 pantothenate kinase 3 0.0258988
MUSK muscle, skeletal, receptor tyrosine kinase 0.0258905
MAP2K5 mitogen-activated protein kinase kinase 5 0.025854
TRIM27 tripartite motif containing 27 0.0258174
TFF3 trefoil factor 3 (intestinal) 0.0257816
OXR1 oxidation resistance 1 0.0257001
IGF1R insulin-like growth factor 1 receptor 0.0256092
TUG1 taurine up-regulated 1 (non-protein coding) 0.0255099
GLCCI1 glucocorticoid induced 1 0.0253823
TMSB4X thymosin beta 4, X-linked 0.0253741
RPLP0 ribosomal protein, large, P0 0.0251769
RPS7 ribosomal protein S7 0.0250985
KPNA6 karyopherin alpha 6 (importin alpha 7) 0.0248777
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.0248652
USP34 ubiquitin specific peptidase 34 0.0247922
MUC1 mucin 1, cell surface associated 0.0247025
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.0246843
PRPF8 pre-mRNA processing factor 8 0.024679
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.024662
C6ORF62 chromosome 6 open reading frame 62 0.0245126
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0244279
RPS16 ribosomal protein S16 0.0240471
INSIG1 insulin induced gene 1 0.0240122
RPS18 ribosomal protein S18 0.0239937
SACK1B scaffolding CK1 anchoring protein B 0.023836
RPS17 ribosomal protein S17 0.0238211
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.0235807
ITGB4 integrin, beta 4 0.0234332
NAV1 neuron navigator 1 0.0233995
RPL6 ribosomal protein L6 0.0233975
RC3H1 ring finger and CCCH-type domains 1 0.0232917
MYO5C myosin VC 0.0231377
SYBU syntabulin (syntaxin-interacting) 0.0231254
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 0.023078
BBX bobby sox homolog (Drosophila) 0.0227916
IL13RA1 interleukin 13 receptor, alpha 1 0.0227103
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.022708
ADNP activity-dependent neuroprotector homeobox 0.0227037
ALCAM activated leukocyte cell adhesion molecule 0.0226304
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 0.0225015
SNX29 sorting nexin 29 0.0224261
CLTB clathrin, light chain B 0.0224035
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) 0.0222221
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0222125
RPL8 ribosomal protein L8 0.0221926
TCAF1 TRPM8 channel-associated factor 1 0.0221654
MYL12B myosin, light chain 12B, regulatory 0.022085
AMZ1 archaelysin family metallopeptidase 1 0.0220191
USP3 ubiquitin specific peptidase 3 0.0219566
TAOK1 TAO kinase 1 0.0218958
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit 0.0218498
ANKRD28 ankyrin repeat domain 28 0.0218296
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 0.0218288
OSBPL2 oxysterol binding protein-like 2 0.0218179
CERS6 ceramide synthase 6 0.0218121
GTF2IRD1 GTF2I repeat domain containing 1 0.0218018
ATG7 autophagy related 7 0.0217713
RAD9A RAD9 homolog A (S. pombe) 0.0217362
RABL6 RAB, member RAS oncogene family-like 6 0.0217331
PTPRF protein tyrosine phosphatase, receptor type, F 0.0216994
SLC38A2 solute carrier family 38, member 2 0.0216501
TPD52L1 tumor protein D52-like 1 0.0215739
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.0215391
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.0215294
IER5L immediate early response 5-like 0.0214319
GPBP1L1 GC-rich promoter binding protein 1-like 1 0.0213389
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.0213221
FOXO3 forkhead box O3 0.0212744
RPS12 ribosomal protein S12 0.0212275
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.0212231
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 0.0212042
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 0.0211528
BIRC6 baculoviral IAP repeat containing 6 0.0209703
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 0.0209414
BABAM2 BRISC and BRCA1 A complex member 2 0.020852
SMAD3 SMAD family member 3 0.0207761
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 0.0207582
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.0205495
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.0205305
NINJ1 ninjurin 1 0.0204946
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.0203018
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.0201675
SDK1 sidekick cell adhesion molecule 1 0.0201558
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.0201303
USP33 ubiquitin specific peptidase 33 0.0201036
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.0200877
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 0.0200692
CALML5 calmodulin-like 5 0.0199712
MLXIP MLX interacting protein 0.0199397
MGLL monoglyceride lipase 0.0198742
SAMD1 sterile alpha motif domain containing 1 0.0198479
NUDCD3 NudC domain containing 3 0.0197828
RPL28 ribosomal protein L28 0.019745
WWP1 WW domain containing E3 ubiquitin protein ligase 1 0.019623
RPS15 ribosomal protein S15 0.0195718
KIAA0319L KIAA0319-like 0.0195007
ARL15 ADP-ribosylation factor-like 15 0.0194167
RUFY1 RUN and FYVE domain containing 1 0.0193298
WIPF1 WAS/WASL interacting protein family, member 1 0.0193127
CNOT10 CCR4-NOT transcription complex, subunit 10 0.0192213
GTF2I general transcription factor IIi 0.0192063
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 0.0191782
UBE2R2 ubiquitin-conjugating enzyme E2R 2 0.0191663
TRERF1 transcriptional regulating factor 1 0.0190895
C1ORF159 chromosome 1 open reading frame 159 0.0189788
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 0.0189201
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0189157
AOPEP aminopeptidase O (putative) 0.0189114
BCAS4 breast carcinoma amplified sequence 4 0.0189099
ZHX3 zinc fingers and homeoboxes 3 0.0189079
MCM4 minichromosome maintenance complex component 4 0.0189053
SSH1 slingshot protein phosphatase 1 0.0188867
RAD51C RAD51 paralog C 0.0188234
TAPBP TAP binding protein (tapasin) 0.0187966
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.018784
TMSB10 thymosin beta 10 0.0187337
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) 0.0187164
ABHD2 abhydrolase domain containing 2 0.0186995
YTHDC2 YTH domain containing 2 0.0186837
TTLL10 tubulin tyrosine ligase-like family member 10 0.0186398
RBM47 RNA binding motif protein 47 0.0185936
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 0.0185215
FAF2 Fas associated factor family member 2 0.0184715
NTAQ1 N-terminal glutamine amidase 1 0.0183996
S100A10 S100 calcium binding protein A10 0.0183948
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0183576
LONRF2 LON peptidase N-terminal domain and ring finger 2 0.018339
KANK2 KN motif and ankyrin repeat domains 2 0.0183345
GOLGA2 golgin A2 0.0182597
BLTP2 bridge-like lipid transfer protein family member 2 0.0182379
CDC73 cell division cycle 73 0.0181697
RBMX RNA binding motif protein, X-linked 0.0181188
RPS11 ribosomal protein S11 0.018112
PRKD2 protein kinase D2 0.0180812
PACS1 phosphofurin acidic cluster sorting protein 1 0.0180509
FAR1 fatty acyl CoA reductase 1 0.0179562
MAN1A1 mannosidase, alpha, class 1A, member 1 0.0179445
SLC39A11 solute carrier family 39, member 11 0.0179239
DDB1 damage-specific DNA binding protein 1, 127kDa 0.017917
DHCR7 7-dehydrocholesterol reductase 0.0178496
RPN2 ribophorin II 0.0178457
TASOR transcription activation suppressor 0.017842
LDAH lipid droplet associated hydrolase 0.0178165
AHNAK AHNAK nucleoprotein 0.0177983
INTS6 integrator complex subunit 6 0.0176659
GABPB2 GA binding protein transcription factor, beta subunit 2 0.0176538
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.0176079
BRCA2 breast cancer 2, early onset 0.0175937
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.0175338
BRD4 bromodomain containing 4 0.0175137
NAV2 neuron navigator 2 0.0175008
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0174332
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.017425
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.0174135
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 0.0174066
AEBP2 AE binding protein 2 0.0174031
TNRC6B trinucleotide repeat containing 6B 0.017395
JTB jumping translocation breakpoint 0.0172911
ACLY ATP citrate lyase 0.0172565
KANSL1 KAT8 regulatory NSL complex subunit 1 0.0172344
TMOD3 tropomodulin 3 (ubiquitous) 0.0172111
ERRFI1 ERBB receptor feedback inhibitor 1 0.0171868
STC1 stanniocalcin 1 0.0170835
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 0.0170535
STC2 stanniocalcin 2 0.0170453
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 0.0170181
KIAA1217 KIAA1217 0.0169785
KANSL1L KAT8 regulatory NSL complex subunit 1-like 0.0169756
GLRA3 glycine receptor, alpha 3 0.0169598
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 0.0169547
DICER1 dicer 1, ribonuclease type III 0.0168996
DNM2 dynamin 2 0.0168787
OCLN occludin 0.0168648
SNX9 sorting nexin 9 0.0168484
ABAT 4-aminobutyrate aminotransferase 0.016789
MLPH melanophilin 0.0167854
HS3ST5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5 0.0167421
TGFB2 transforming growth factor, beta 2 0.0167363
IREB2 iron-responsive element binding protein 2 0.0166333
RAP1GAP2 RAP1 GTPase activating protein 2 0.0166268
CERS2 ceramide synthase 2 0.0166142
BTN3A3 butyrophilin, subfamily 3, member A3 0.0166084
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.0166055
FAM174B family with sequence similarity 174, member B 0.0165279
JARID2 jumonji, AT rich interactive domain 2 0.0165172
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 0.0164686
KMT2E lysine (K)-specific methyltransferase 2E 0.0164684
HDLBP high density lipoprotein binding protein 0.0164282
EYA2 EYA transcriptional coactivator and phosphatase 2 0.0163894
ARHGAP12 Rho GTPase activating protein 12 0.0163625
MAPK8 mitogen-activated protein kinase 8 0.0163229
COG8 component of oligomeric golgi complex 8 0.0162824
TBCK TBC1 domain containing kinase 0.0162529
CDC14A cell division cycle 14A 0.0162484
RPL4 ribosomal protein L4 0.016227
BAZ2A bromodomain adjacent to zinc finger domain, 2A 0.0161929
CENPF centromere protein F, 350/400kDa 0.0161566
SASH1 SAM and SH3 domain containing 1 0.016123
POGZ pogo transposable element with ZNF domain 0.0161142
METRNL meteorin, glial cell differentiation regulator-like 0.0160898
YIPF2 Yip1 domain family, member 2 0.0160305
NIPSNAP1 nipsnap homolog 1 (C. elegans) 0.015992
MTMR3 myotubularin related protein 3 0.0159841
CD151 CD151 molecule (Raph blood group) 0.0159718
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 0.0159414
PFDN5 prefoldin subunit 5 0.015908
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0158917
R3HCC1L R3H domain and coiled-coil containing 1-like 0.0158831
SMG5 SMG5 nonsense mediated mRNA decay factor 0.0158358
LY6E lymphocyte antigen 6 complex, locus E 0.015829
TBC1D17 TBC1 domain family, member 17 0.0157902
RNF213 ring finger protein 213 0.0157305
MRS2 MRS2 magnesium transporter 0.0156099
LDLRAD3 low density lipoprotein receptor class A domain containing 3 0.015604
RPN1 ribophorin I 0.0155602
RPRD2 regulation of nuclear pre-mRNA domain containing 2 0.0155591
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa 0.0155568
PLIN3 perilipin 3 0.0155554
SCAF11 SR-related CTD-associated factor 11 0.0155012
CLTCL1 clathrin, heavy chain-like 1 0.0154623
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 0.0154607
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 0.0154575
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 0.015437
CYBA cytochrome b-245, alpha polypeptide 0.0154146
SYT1 synaptotagmin I 0.015403
CAPN8 calpain 8 0.015377
BOD1L1 biorientation of chromosomes in cell division 1-like 1 0.0153582
SFTPA2 surfactant protein A2 0.0153568
MACROD1 MACRO domain containing 1 0.0153484
MXD4 MAX dimerization protein 4 0.0153467
TSLIG1 tRNA splicing ligase complex subunit 1 0.0152662
RPL5 ribosomal protein L5 0.0152253
RBPMS RNA binding protein with multiple splicing 0.0151726
MAPK14 mitogen-activated protein kinase 14 0.0151518
SOS2 son of sevenless homolog 2 (Drosophila) 0.0151423
SPAG9 sperm associated antigen 9 0.015138
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.0151222
CCT7 chaperonin containing TCP1, subunit 7 (eta) 0.0151046
LGALS12 lectin, galactoside-binding, soluble, 12 0.0150545
RSU1 Ras suppressor protein 1 0.0150341
KRTAP11-1 keratin associated protein 11-1 0.015019
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.0150188
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa 0.0150083
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 0.0149994
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 0.0149896
UQCRC2 ubiquinol-cytochrome c reductase core protein II 0.0149703
FNBP1 formin binding protein 1 0.0149453
NICOL1 NELL2 interacting cell ontogeny regulator 1 0.0149235
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 0.014908
BRI3BP BRI3 binding protein 0.0148825
MREG melanoregulin 0.0148655
PHF3 PHD finger protein 3 0.0148649
CDK14 cyclin-dependent kinase 14 0.0148604
WDR59 WD repeat domain 59 0.0148579
ZDHHC14 zinc finger, DHHC-type containing 14 0.0148297
LATS2 large tumor suppressor kinase 2 0.0148273
RABGAP1 RAB GTPase activating protein 1 0.0148051
RPSA ribosomal protein SA 0.0147896
PLEKHA6 pleckstrin homology domain containing, family A member 6 0.0147876
TRIQK triple QxxK/R motif containing 0.0147854
RPS4X ribosomal protein S4, X-linked 0.0147739
ZNF83 zinc finger protein 83 0.0147628
CATSPERG catsper channel auxiliary subunit gamma 0.0147575
USP42 ubiquitin specific peptidase 42 0.0147508
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 0.0147243
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 0.0147142
BCAR3 breast cancer anti-estrogen resistance 3 0.0146864
TP53 tumor protein p53 0.0146846
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 0.0146785
H2BC8 H2B clustered histone 8 0.0146666
CCDC6 coiled-coil domain containing 6 0.0145575
CTTNBP2NL CTTNBP2 N-terminal like 0.0145399
MPG N-methylpurine-DNA glycosylase 0.0145218
SECISBP2 SECIS binding protein 2 0.0145212
GNA12 guanine nucleotide binding protein (G protein) alpha 12 0.0145186
SLC35H1 solute carrier family 35 member H1 0.0145118
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.0145103
CLDN3 claudin 3 0.0144889
LGALS3 lectin, galactoside-binding, soluble, 3 0.0144317
PAIP2 poly(A) binding protein interacting protein 2 0.0144283
WAPL WAPL cohesin release factor 0.0143557
SSR1 signal sequence receptor, alpha 0.0143374
OGA O-GlcNAcase 0.014288
CSNK1G1 casein kinase 1, gamma 1 0.0142743
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 0.0142662
TMTC3 transmembrane and tetratricopeptide repeat containing 3 0.0142612
SREBF2 sterol regulatory element binding transcription factor 2 0.0142567
KSR2 kinase suppressor of ras 2 0.0141596
RETREG3 reticulophagy regulator family member 3 0.0141564
HDGF hepatoma-derived growth factor 0.0141427
TMEM117 transmembrane protein 117 0.0141358
DOK7 docking protein 7 0.0141207
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.0141161
KANTR KDM5C adjacent non-coding transcript 0.0140873
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 0.0140837
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.0140295
RO60 Ro60, Y RNA binding protein 0.0140106
MYO1B myosin IB 0.0139968
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0139751
PHB1 prohibitin 1 0.0139621
DPY30 dpy-30 homolog (C. elegans) 0.0139578
S100A14 S100 calcium binding protein A14 0.0139204
SPRED2 sprouty-related, EVH1 domain containing 2 0.0138954
NUSAP1 nucleolar and spindle associated protein 1 0.0138951
RPS24 ribosomal protein S24 0.0138948
HMGN1 high mobility group nucleosome binding domain 1 0.0138643
NBPF1 neuroblastoma breakpoint family, member 1 0.0138582
ACIN1 apoptotic chromatin condensation inducer 1 0.0138442
CTSB cathepsin B 0.0138216
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.0138135
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.0137907
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.0137663
RPS27A ribosomal protein S27a 0.0137656
RSRP1 arginine/serine-rich protein 1 0.0137623
OCIAD2 OCIA domain containing 2 0.0137541
PARG poly (ADP-ribose) glycohydrolase 0.0137339
PLK2 polo-like kinase 2 0.0137202
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 0.013708
MGA MGA, MAX dimerization protein 0.0137051
UGCG UDP-glucose ceramide glucosyltransferase 0.0136944
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) 0.0136562
NINL ninein-like 0.0136379
TPT1 tumor protein, translationally-controlled 1 0.0136207
RDX radixin 0.0136177
UBXN4 UBX domain protein 4 0.0136095
HEXA hexosaminidase A (alpha polypeptide) 0.0135954
DEPDC5 DEP domain containing 5 0.0135715
MANBA mannosidase, beta A, lysosomal 0.0134918
TUFT1 tuftelin 1 0.0134909
DTNB dystrobrevin, beta 0.0134482
NALF1 NALCN channel auxiliary factor 1 0.0133611
ZFR zinc finger RNA binding protein 0.0133381
PIGN phosphatidylinositol glycan anchor biosynthesis, class N 0.0133364
GAB2 GRB2-associated binding protein 2 0.0133273
SHANK2 SH3 and multiple ankyrin repeat domains 2 0.0133068
DENND1A DENN/MADD domain containing 1A 0.0133047
TACC2 transforming, acidic coiled-coil containing protein 2 0.0132994
MYLIP myosin regulatory light chain interacting protein 0.0132957
ZNF512B zinc finger protein 512B 0.0132818
TGFB1 transforming growth factor, beta 1 0.0132799
MED12L mediator complex subunit 12-like 0.0132757
PYGL phosphorylase, glycogen, liver 0.0132632
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 0.0132444
KCTD20 potassium channel tetramerization domain containing 20 0.013225
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0131807
DBT dihydrolipoamide branched chain transacylase E2 0.0131732
PRKCSH protein kinase C substrate 80K-H 0.0131582
RORA RAR-related orphan receptor A 0.0131556
DOCK1 dedicator of cytokinesis 1 0.0131111
NF1 neurofibromin 1 0.0130898
SPTY2D1 SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) 0.0130305
GOLGA8B golgin A8 family, member B 0.0130177
TOB2 transducer of ERBB2, 2 0.0130144
MEPCE methylphosphate capping enzyme 0.0129792
RBM15 RNA binding motif protein 15 0.0129708
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0129695
PPHLN1 periphilin 1 0.0129468
CCDC125 coiled-coil domain containing 125 0.0129424
NOA1 nitric oxide associated 1 0.0129008
SLC31A1 solute carrier family 31 (copper transporter), member 1 0.0128684
CHD9 chromodomain helicase DNA binding protein 9 0.0128644
TMEM116 transmembrane protein 116 0.0128498
ATP11C ATPase, class VI, type 11C 0.0128492
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 0.0128303
FBXW8 F-box and WD repeat domain containing 8 0.012829
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) 0.0128289
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae) 0.0128106
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 0.0128094
ACVR1 activin A receptor, type I 0.0127363
PRKX protein kinase, X-linked 0.0127155
MZT2A mitotic spindle organizing protein 2A 0.0127145
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit 0.0127105
UBA2 ubiquitin-like modifier activating enzyme 2 0.0126951
SRSF3 serine/arginine-rich splicing factor 3 0.0126897
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.0126818
CALU calumenin 0.012679
CFDP1 craniofacial development protein 1 0.012647
FOXRED2 FAD-dependent oxidoreductase domain containing 2 0.0126336
TM9SF2 transmembrane 9 superfamily member 2 0.0126294
PTGR1 prostaglandin reductase 1 0.0126212
FXYD3 FXYD domain containing ion transport regulator 3 0.0126193
MTIF2 mitochondrial translational initiation factor 2 0.0126178
ATOSA atos homolog A 0.0126164
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 0.0125705
LRRC58 leucine rich repeat containing 58 0.0125338
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.0125239
NQO1 NAD(P)H dehydrogenase, quinone 1 0.012453
HTATSF1 HIV-1 Tat specific factor 1 0.0123928
COL4A5 collagen, type IV, alpha 5 0.0123778
CORO1B coronin, actin binding protein, 1B 0.0123655
ATXN3 ataxin 3 0.0123568
RPL27A ribosomal protein L27a 0.0123447
EEIG1 estrogen-induced osteoclastogenesis regulator 1 0.0123261
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 0.0123108
BTBD1 BTB (POZ) domain containing 1 0.0123085
LOC112694756 uncharaterized LOC112694756 0.0123003

decreased expression

Symbol Name Standardized Value
WWOX WW domain containing oxidoreductase -0.165574
SULF2 sulfatase 2 -0.110655
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.109362
GATA3 GATA binding protein 3 -0.1073
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 -0.0854821
SIPA1L1 signal-induced proliferation-associated 1 like 1 -0.0854807
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0849558
TPM4 tropomyosin 4 -0.0815251
VMP1 vacuole membrane protein 1 -0.0751995
TRPS1 trichorhinophalangeal syndrome I -0.0734458
GPC6 glypican 6 -0.0730991
DSCAM Down syndrome cell adhesion molecule -0.0699654
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0679789
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.0678203
NCAM2 neural cell adhesion molecule 2 -0.0662478
PARD6B par-6 family cell polarity regulator beta -0.0635298
TRIM33 tripartite motif containing 33 -0.0633913
TRIM37 tripartite motif containing 37 -0.0609128
AREG amphiregulin -0.0565236
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 -0.0559531
PBX3 pre-B-cell leukemia homeobox 3 -0.0526964
IFI6 interferon, alpha-inducible protein 6 -0.0519578
MALRD1 MAM and LDL receptor class A domain containing 1 -0.0507059
DIAPH1 diaphanous-related formin 1 -0.0485489
SMYD3 SET and MYND domain containing 3 -0.0482285
MKI67 marker of proliferation Ki-67 -0.0468589
AGR2 anterior gradient 2 -0.0461833
CENPP centromere protein P -0.045983
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0455985
STK24 serine/threonine kinase 24 -0.0442716
GFRA1 GDNF family receptor alpha 1 -0.0439733
MAST4 microtubule associated serine/threonine kinase family member 4 -0.0436711
COX6C cytochrome c oxidase subunit VIc -0.0405182
PRKCE protein kinase C, epsilon -0.0403939
TULP4 tubby like protein 4 -0.0397132
ZFAND3 zinc finger, AN1-type domain 3 -0.0395631
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.038684
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.0368094
ATAD2 ATPase family, AAA domain containing 2 -0.0363076
THSD4 thrombospondin, type I, domain containing 4 -0.0361979
CPA6 carboxypeptidase A6 -0.0359797
HIPK2 homeodomain interacting protein kinase 2 -0.0352162
PTPRG protein tyrosine phosphatase, receptor type, G -0.0349697
TBC1D5 TBC1 domain family, member 5 -0.0349211
MACROD2 MACRO domain containing 2 -0.0340561
TAC4 tachykinin 4 (hemokinin) -0.0336638
YLPM1 YLP motif containing 1 -0.0335559
WWC1 WW and C2 domain containing 1 -0.0329976
KRT8 keratin 8, type II -0.0328725
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0328402
LRP1B low density lipoprotein receptor-related protein 1B -0.032453
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 -0.0319875
KMT2A lysine (K)-specific methyltransferase 2A -0.0317026
GMDS GDP-mannose 4,6-dehydratase -0.0314944
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -0.0312781
CLTC clathrin, heavy chain (Hc) -0.0306446
NRIP1 nuclear receptor interacting protein 1 -0.0305119
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0302264
TMEM64 transmembrane protein 64 -0.030223
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 -0.0302054
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0300713
MYH9 myosin, heavy chain 9, non-muscle -0.0298597
PLEC plectin -0.0298142
TUBB tubulin, beta class I -0.0295829
NR6A1 nuclear receptor subfamily 6, group A, member 1 -0.0293389
GREB1L growth regulation by estrogen in breast cancer-like -0.0290948
SIK3 SIK family kinase 3 -0.0288556
TCF12 transcription factor 12 -0.0288533
KMT2C lysine (K)-specific methyltransferase 2C -0.0288504
UBB ubiquitin B -0.0288091
TMEM164 transmembrane protein 164 -0.0281286
SHISA9 shisa family member 9 -0.0281177
CLASP1 cytoplasmic linker associated protein 1 -0.0277265
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -0.0276425
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.0275242
SETD5 SET domain containing 5 -0.0272882
LPP LIM domain containing preferred translocation partner in lipoma -0.0270896
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.0269059
ARHGAP11B Rho GTPase activating protein 11B -0.0267464
BMP7 bone morphogenetic protein 7 -0.0267289
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha -0.0267228
ATXN10 ataxin 10 -0.0266406
NSD1 nuclear receptor binding SET domain protein 1 -0.026548
JMJD1C jumonji domain containing 1C -0.0263093
PCDH7 protocadherin 7 -0.0261763
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -0.0256956
ANKRD17 ankyrin repeat domain 17 -0.0255145
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.025383
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.0253054
PKM pyruvate kinase, muscle -0.025271
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 -0.0252046
PUM2 pumilio RNA-binding family member 2 -0.0251807
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -0.0251153
NPDC1 neural proliferation, differentiation and control, 1 -0.024943
CLSTN2 calsyntenin 2 -0.0248764
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.024844
HIPK1 homeodomain interacting protein kinase 1 -0.0248197
ENO1 enolase 1, (alpha) -0.0247179
EIF3B eukaryotic translation initiation factor 3, subunit B -0.0244409
PDZRN3 PDZ domain containing ring finger 3 -0.0244153
AGO3 argonaute RISC catalytic component 3 -0.0243095
NOP58 NOP58 ribonucleoprotein -0.0243043
TNPO1 transportin 1 -0.0242964
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.024109
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) -0.0240591
RREB1 ras responsive element binding protein 1 -0.0238829
FAF1 Fas (TNFRSF6) associated factor 1 -0.0238763
EDF1 endothelial differentiation-related factor 1 -0.0237551
NRDC nardilysin convertase -0.0237139
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0235852
SRRM1 serine/arginine repetitive matrix 1 -0.0235818
NPNT nephronectin -0.0234012
SRPK1 SRSF protein kinase 1 -0.0233763
THOC7 THO complex 7 -0.0233452
GLG1 golgi glycoprotein 1 -0.0232647
NUMB numb homolog (Drosophila) -0.0231878
SCAMP3 secretory carrier membrane protein 3 -0.0230432
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0230405
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.0229886
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 -0.0229633
METTL8 methyltransferase like 8 -0.0229031
KIAA1958 KIAA1958 -0.0227049
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0226183
ASCC3 activating signal cointegrator 1 complex subunit 3 -0.0225541
DIAPH2 diaphanous-related formin 2 -0.0225257
GSK3B glycogen synthase kinase 3 beta -0.022414
SKA2 spindle and kinetochore associated complex subunit 2 -0.0222984
OLA1 Obg-like ATPase 1 -0.0222663
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.0222374
NUP153 nucleoporin 153kDa -0.0222051
GRB2 growth factor receptor-bound protein 2 -0.0221928
COPE coatomer protein complex, subunit epsilon -0.0220496
NT5DC1 5'-nucleotidase domain containing 1 -0.0219324
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -0.0219002
SHROOM3 shroom family member 3 -0.0216289
GPATCH2 G patch domain containing 2 -0.0216267
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.0216116
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.0215501
RFWD3 ring finger and WD repeat domain 3 -0.0214697
H3-3B H3.3 histone B -0.0214367
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -0.0214335
VCP valosin containing protein -0.0214269
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -0.0214268
GLO1 glyoxalase I -0.0213619
RBBP4 retinoblastoma binding protein 4 -0.0213265
LARP4B La ribonucleoprotein domain family, member 4B -0.0213152
NPC2 Niemann-Pick disease, type C2 -0.0213124
NPAS3 neuronal PAS domain protein 3 -0.021292
STARD13 StAR-related lipid transfer (START) domain containing 13 -0.0212556
STRN3 striatin, calmodulin binding protein 3 -0.0212555
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.0212196
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.0212156
NOCT nocturnin -0.0211976
MORF4L2 mortality factor 4 like 2 -0.0211613
TCF25 transcription factor 25 (basic helix-loop-helix) -0.0211173
JUP junction plakoglobin -0.0210943
RAB7A RAB7A, member RAS oncogene family -0.0210773
TMEM132A transmembrane protein 132A -0.021074
SRRM2 serine/arginine repetitive matrix 2 -0.0210399
GMPS guanine monphosphate synthase -0.0210106
CHLSN cholesin -0.020983
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B -0.0208687
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0208117
TOM1L2 target of myb1-like 2 (chicken) -0.0208046
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.0207974
BTBD7 BTB (POZ) domain containing 7 -0.0207236
IFI27 interferon, alpha-inducible protein 27 -0.0206151
FANCI Fanconi anemia, complementation group I -0.0203612
ARHGAP32 Rho GTPase activating protein 32 -0.0203146
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.020253
MTCH2 mitochondrial carrier 2 -0.0202029
PHF14 PHD finger protein 14 -0.0200844
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.020057
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -0.0200397
HM13 histocompatibility (minor) 13 -0.0200301
GPATCH8 G patch domain containing 8 -0.0200227
RALY RALY heterogeneous nuclear ribonucleoprotein -0.0199492
PRC1 protein regulator of cytokinesis 1 -0.0199403
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0199238
MYO16 myosin XVI -0.0198493
ANKRD11 ankyrin repeat domain 11 -0.0198215
ATRNL1 attractin-like 1 -0.0198078
TEX14 testis expressed 14 -0.0197628
LMNA lamin A/C -0.019759
LYPD6B LY6/PLAUR domain containing 6B -0.0197452
ADD1 adducin 1 (alpha) -0.0195708
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -0.0195645
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0195561
PITPNA phosphatidylinositol transfer protein, alpha -0.0195165
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.0195145
CCDC47 coiled-coil domain containing 47 -0.0194943
PPP4R3A protein phosphatase 4 regulatory subunit 3A -0.0194489
PPP6R3 protein phosphatase 6, regulatory subunit 3 -0.019436
UBE4B ubiquitination factor E4B -0.019397
DIS3L DIS3 like exosome 3'-5' exoribonuclease -0.0192864
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.0192696
DAAM1 dishevelled associated activator of morphogenesis 1 -0.0191902
DENR density-regulated protein -0.0190385
LRP10 low density lipoprotein receptor-related protein 10 -0.0190178
NUP188 nucleoporin 188kDa -0.0189816
MAST2 microtubule associated serine/threonine kinase 2 -0.0189591
GON4L gon-4-like (C. elegans) -0.0189446
ATP5MJ ATP synthase membrane subunit j -0.0189365
RERG RAS-like, estrogen-regulated, growth inhibitor -0.0189001
ANO10 anoctamin 10 -0.0188951
PCED1B PC-esterase domain containing 1B -0.0188519
ARID1B AT rich interactive domain 1B (SWI1-like) -0.0188496
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 -0.018849
VTA1 vesicle (multivesicular body) trafficking 1 -0.0188368
GPHN gephyrin -0.018836
TRIR telomerase RNA component interacting RNase -0.0187936
SNX1 sorting nexin 1 -0.0187532
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.0187097
SEL1L sel-1 suppressor of lin-12-like (C. elegans) -0.018689
RNASE12 ribonuclease, RNase A family, 12 (non-active) -0.0186496
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0186083
HCFC1 host cell factor C1 -0.0186078
PTPRA protein tyrosine phosphatase, receptor type, A -0.0185946
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.0185885
TECPR2 tectonin beta-propeller repeat containing 2 -0.0185399
PIEZO1 piezo-type mechanosensitive ion channel component 1 -0.0185372
IP6K1 inositol hexakisphosphate kinase 1 -0.0184844
UNK unkempt family zinc finger -0.0184596
CEP350 centrosomal protein 350kDa -0.0184511
MIDEAS mitotic deacetylase associated SANT domain protein -0.0184436
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) -0.0184183
FERMT2 fermitin family member 2 -0.0183827
FBXO42 F-box protein 42 -0.0183672
TEX2 testis expressed 2 -0.0181955
SCLT1 sodium channel and clathrin linker 1 -0.018164
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -0.018158
ACTR3 ARP3 actin-related protein 3 homolog (yeast) -0.0181482
MRFAP1 Morf4 family associated protein 1 -0.0180199
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -0.0180033
ACTN1 actinin, alpha 1 -0.0179729
FAM222B family with sequence similarity 222, member B -0.0179607
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -0.0179582
SMC1A structural maintenance of chromosomes 1A -0.0179345
NUP62 nucleoporin 62kDa -0.0179202
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -0.0178906
PDE8A phosphodiesterase 8A -0.0178311
FANCM Fanconi anemia, complementation group M -0.0178218
RPS25 ribosomal protein S25 -0.0177995
POLK polymerase (DNA directed) kappa -0.0176408
NUP58 nucleoporin 58 -0.0176055
AP1M2 adaptor-related protein complex 1, mu 2 subunit -0.0175843
FBXL17 F-box and leucine-rich repeat protein 17 -0.0175345
SYAP1 synapse associated protein 1 -0.0175153
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -0.0175077
ATG10 autophagy related 10 -0.0175068
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.0174916
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit -0.017445
SINHCAF SIN3-HDAC complex associated factor -0.0174449
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa -0.0174379
NCKAP5 NCK-associated protein 5 -0.0174063
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -0.0173969
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -0.0173792
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -0.0173533
ARHGAP35 Rho GTPase activating protein 35 -0.0173359
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0173153
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 -0.0172859
LATS1 large tumor suppressor kinase 1 -0.0172609
TLK2 tousled-like kinase 2 -0.0172438
PCNT pericentrin -0.0171674
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.0171432
KATNBL1 katanin p80 subunit B-like 1 -0.0171117
RAD51B RAD51 paralog B -0.0171035
ZC3H18 zinc finger CCCH-type containing 18 -0.0170859
SLC39A9 solute carrier family 39, member 9 -0.0170729
IGFBP4 insulin-like growth factor binding protein 4 -0.017014
FOXK1 forkhead box K1 -0.0169973
RYBP RING1 and YY1 binding protein -0.0169949
ETV6 ets variant 6 -0.0169763
RSRC1 arginine/serine-rich coiled-coil 1 -0.0169453
NSD3 nuclear receptor binding SET domain protein 3 -0.016926
TENM3 teneurin transmembrane protein 3 -0.0169001
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 -0.0168959
CDK4 cyclin-dependent kinase 4 -0.0168536
PPP6C protein phosphatase 6, catalytic subunit -0.0168503
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0168335
ANLN anillin, actin binding protein -0.0168068
PPCDC phosphopantothenoylcysteine decarboxylase -0.01679
ERN1 endoplasmic reticulum to nucleus signaling 1 -0.0167503
CCDC88C coiled-coil domain containing 88C -0.0167449
UBR2 ubiquitin protein ligase E3 component n-recognin 2 -0.0167375
MAML3 mastermind-like 3 (Drosophila) -0.0167237
MYO9B myosin IXB -0.0167161
NIPAL2 NIPA-like domain containing 2 -0.016716
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -0.0166591
SPATS2L spermatogenesis associated, serine-rich 2-like -0.0165863
PCNX1 pecanex 1 -0.0165657
EARS2 glutamyl-tRNA synthetase 2, mitochondrial -0.0165282
NRG3 neuregulin 3 -0.0164863
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.0164808
TRIM14 tripartite motif containing 14 -0.0164686
SND1 staphylococcal nuclease and tudor domain containing 1 -0.0164541
WDHD1 WD repeat and HMG-box DNA binding protein 1 -0.016436
CEP128 centrosomal protein 128kDa -0.0163852
RBL2 retinoblastoma-like 2 -0.0163827
ISG15 ISG15 ubiquitin-like modifier -0.0163266
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) -0.0163173
C19ORF53 chromosome 19 open reading frame 53 -0.0162814
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 -0.0162534
LRIF1 ligand dependent nuclear receptor interacting factor 1 -0.016234
TRAM1 translocation associated membrane protein 1 -0.0161829
TPX2 TPX2, microtubule-associated -0.0161456
KDM3B lysine (K)-specific demethylase 3B -0.0160769
DCPH1 damage control phosphatase 1 -0.016051
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -0.0159755
TOP3A topoisomerase (DNA) III alpha -0.0159543
E2F3 E2F transcription factor 3 -0.0159192
TPR translocated promoter region, nuclear basket protein -0.0159191
ZNF148 zinc finger protein 148 -0.0158971
ZFHX3 zinc finger homeobox 3 -0.0158514
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) -0.0158496
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 -0.0158486
GFOD2 glucose-fructose oxidoreductase domain containing 2 -0.0158392
EHBP1 EH domain binding protein 1 -0.0158386
MRTFB myocardin related transcription factor B -0.0158346
PGRMC2 progesterone receptor membrane component 2 -0.0158308
ZCCHC17 zinc finger, CCHC domain containing 17 -0.015737
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.0157356
USP25 ubiquitin specific peptidase 25 -0.0157204
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -0.0156842
RNF38 ring finger protein 38 -0.0156786
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0156665
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0156549
BAZ1A bromodomain adjacent to zinc finger domain, 1A -0.0156395
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.015624
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -0.0155901
TMPO thymopoietin -0.01557
TPBG trophoblast glycoprotein -0.0155409
ESYT1 extended synaptotagmin-like protein 1 -0.0155344
ITGB5 integrin, beta 5 -0.0155318
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase -0.0155149
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -0.0154607
SCYL2 SCY1-like 2 (S. cerevisiae) -0.0154449
MYH14 myosin, heavy chain 14, non-muscle -0.0154443
DGKH diacylglycerol kinase, eta -0.0154416
DCTN5 dynactin 5 (p25) -0.015388
ELOB elongin B -0.0153867
CDK12 cyclin-dependent kinase 12 -0.0153459
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -0.0153089
SYTL4 synaptotagmin-like 4 -0.0152946
PNISR PNN-interacting serine/arginine-rich protein -0.0152864
SEC63 SEC63 homolog (S. cerevisiae) -0.0152673
GRN granulin -0.0152647
TACC1 transforming, acidic coiled-coil containing protein 1 -0.0152601
METTL15 methyltransferase like 15 -0.0152392
RAD23A RAD23 homolog A (S. cerevisiae) -0.0151915
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.0151668
ZC3H3 zinc finger CCCH-type containing 3 -0.0151437
TRIP12 thyroid hormone receptor interactor 12 -0.0151424
RPS9 ribosomal protein S9 -0.0151323
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0150945
PUS7 pseudouridylate synthase 7 (putative) -0.0150855
MYO1E myosin IE -0.0150677
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.0150661
NSD2 nuclear receptor binding SET domain protein 2 -0.0150559
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase -0.0150464
RFC3 replication factor C (activator 1) 3, 38kDa -0.0150214
PITRM1 pitrilysin metallopeptidase 1 -0.0149956
IARS1 isoleucyl-tRNA synthetase 1 -0.0149858
ARFGEF3 ARFGEF family member 3 -0.0149835
CADM1 cell adhesion molecule 1 -0.0149782
SP3 Sp3 transcription factor -0.0149513
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.0149333
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -0.0149236
LMX1B LIM homeobox transcription factor 1, beta -0.0149234
CHD6 chromodomain helicase DNA binding protein 6 -0.0149163
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.0148795
RBM6 RNA binding motif protein 6 -0.0148721
TRAPPC12 trafficking protein particle complex 12 -0.014872
EPPK1 epiplakin 1 -0.0148641
PTGES3 prostaglandin E synthase 3 (cytosolic) -0.01486
ECD ecdysoneless homolog (Drosophila) -0.0147881
SFPQ splicing factor proline/glutamine-rich -0.0147864
CHMP1A charged multivesicular body protein 1A -0.0147393
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.0147077
NUP155 nucleoporin 155kDa -0.0146823
SOS1 son of sevenless homolog 1 (Drosophila) -0.0146463
APOOL apolipoprotein O-like -0.0146424
BLM Bloom syndrome, RecQ helicase-like -0.0146169
RSF1 remodeling and spacing factor 1 -0.014604
ALG8 ALG8, alpha-1,3-glucosyltransferase -0.0145924
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 -0.0145799
WASF2 WAS protein family, member 2 -0.0145754
CKAP5 cytoskeleton associated protein 5 -0.0145591
PARD3B par-3 family cell polarity regulator beta -0.0145262
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -0.014508
TPM3 tropomyosin 3 -0.0144976
NIPBL Nipped-B homolog (Drosophila) -0.0144975
ARHGAP17 Rho GTPase activating protein 17 -0.0144792
TRIM25 tripartite motif containing 25 -0.0144551
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 -0.0144334
GNB5 guanine nucleotide binding protein (G protein), beta 5 -0.0144202
DHRS7B dehydrogenase/reductase (SDR family) member 7B -0.0143789
RAB33B RAB33B, member RAS oncogene family -0.0143604
GATAD2A GATA zinc finger domain containing 2A -0.0143593
THBS1 thrombospondin 1 -0.014358
EXD3 exonuclease 3'-5' domain containing 3 -0.0143521
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase -0.0143463
TLN2 talin 2 -0.0143397
TTC17 tetratricopeptide repeat domain 17 -0.0143241
AP2M1 adaptor-related protein complex 2, mu 1 subunit -0.0143195
TAMM41 TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae) -0.014315
CARM1 coactivator-associated arginine methyltransferase 1 -0.0143068
KNL1 kinetochore scaffold 1 -0.0142987
DCAF5 DDB1 and CUL4 associated factor 5 -0.0142954
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial -0.0142905
PRIM2 primase, DNA, polypeptide 2 (58kDa) -0.0142396
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 -0.0142086
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 -0.0141981
BZW2 basic leucine zipper and W2 domains 2 -0.0141979
CHMP4B charged multivesicular body protein 4B -0.0141894
RPAP2 RNA polymerase II associated protein 2 -0.014184
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -0.0141725
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) -0.0141695
NR2C1 nuclear receptor subfamily 2, group C, member 1 -0.0141454
KDM1A lysine (K)-specific demethylase 1A -0.0141407
CDK5RAP2 CDK5 regulatory subunit associated protein 2 -0.0141102
IPO9 importin 9 -0.0141071
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.0140963
MEF2A myocyte enhancer factor 2A -0.0140886
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -0.0140725
RANBP17 RAN binding protein 17 -0.0140399
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) -0.0140354
SVIL supervillin -0.0139906
RNF34 ring finger protein 34, E3 ubiquitin protein ligase -0.01397
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -0.0139421
MFSD11 major facilitator superfamily domain containing 11 -0.0139323
LMNB2 lamin B2 -0.0138836
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -0.0138606
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A -0.0138551
EEF2K eukaryotic elongation factor 2 kinase -0.0138337
SCAF8 SR-related CTD-associated factor 8 -0.0138166
TM7SF3 transmembrane 7 superfamily member 3 -0.0137964
DYNLL2 dynein, light chain, LC8-type 2 -0.0137947
PPIG peptidylprolyl isomerase G (cyclophilin G) -0.0137855
RPL29 ribosomal protein L29 -0.0137776
ACACA acetyl-CoA carboxylase alpha -0.01377
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -0.0137525
MOCOS molybdenum cofactor sulfurase -0.0137149
FKBP4 FK506 binding protein 4, 59kDa -0.0136841
SPNS1 spinster homolog 1 (Drosophila) -0.0136805
REPS1 RALBP1 associated Eps domain containing 1 -0.0136607
SPPL3 signal peptide peptidase like 3 -0.0136588
CCT2 chaperonin containing TCP1, subunit 2 (beta) -0.0136402
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A -0.0136354
HEATR6 HEAT repeat containing 6 -0.0136313
RRP36 ribosomal RNA processing 36 homolog (S. cerevisiae) -0.0136269
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -0.0136097
ZC3H13 zinc finger CCCH-type containing 13 -0.0136073
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.0135833
BLTP3A bridge-like lipid transfer protein family member 3A -0.0135801
FRYL FRY-like -0.0135792
ITCH itchy E3 ubiquitin protein ligase -0.0135347
LRRC69 leucine rich repeat containing 69 -0.0135208
PTGES2 prostaglandin E synthase 2 -0.0134943
CD9 CD9 molecule -0.0134551
XPR1 xenotropic and polytropic retrovirus receptor 1 -0.0134462
ZNF718 zinc finger protein 718 -0.0134181
LAMC1 laminin, gamma 1 (formerly LAMB2) -0.0134163
IQANK1 IQ motif and ankyrin repeat containing 1 -0.0134128
WEE1 WEE1 G2 checkpoint kinase -0.0133765
PIAS1 protein inhibitor of activated STAT, 1 -0.013375
PTBP3 polypyrimidine tract binding protein 3 -0.013374
RABEPK Rab9 effector protein with kelch motifs -0.0133658
PGCKA1 PDCD10 and GCKIII kinases associated 1 -0.0133446
MLYCD malonyl-CoA decarboxylase -0.0133409
ZBTB4 zinc finger and BTB domain containing 4 -0.0133256
DMTF1 cyclin D binding myb-like transcription factor 1 -0.0133174
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -0.0133134
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -0.0133134
UNC45A unc-45 homolog A (C. elegans) -0.0132987
EYA3 EYA transcriptional coactivator and phosphatase 3 -0.0132936
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) -0.0132906
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C -0.0132455
HP1BP3 heterochromatin protein 1, binding protein 3 -0.0132147
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.0132084
HDGFL3 HDGF like 3 -0.0131957
PTPRK protein tyrosine phosphatase, receptor type, K -0.0131761
PA2G4 proliferation-associated 2G4, 38kDa -0.0131527
MAP7D3 MAP7 domain containing 3 -0.0131443
CA12 carbonic anhydrase XII -0.0131212
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -0.0130649
C1ORF21 chromosome 1 open reading frame 21 -0.013062
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa -0.0130514
ARSG arylsulfatase G -0.0130496
FAM168A family with sequence similarity 168, member A -0.013035
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa -0.0130345
POTEF POTE ankyrin domain family, member F -0.0130298
PDS5B PDS5 cohesin associated factor B -0.013027
CENPB centromere protein B, 80kDa -0.0130223
FNDC3A fibronectin type III domain containing 3A -0.0130174
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -0.0129684
POGK pogo transposable element with KRAB domain -0.0129653
GLRX3 glutaredoxin 3 -0.0129567
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 -0.012926
PGR progesterone receptor -0.012901