MCF7_GSK J1_1µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description GSK J1 1µM perturbation in MCF7 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the MCF7_GSK J1_1µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
TFF1 trefoil factor 1 0.125521
MSI2 musashi RNA-binding protein 2 0.0999258
TPM4 tropomyosin 4 0.0929941
DSPP dentin sialophosphoprotein 0.0867339
USP32 ubiquitin specific peptidase 32 0.0857632
CSDE1 cold shock domain containing E1, RNA-binding 0.0833042
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0823171
IFI6 interferon, alpha-inducible protein 6 0.0815648
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0808059
NRIP1 nuclear receptor interacting protein 1 0.0801674
NCOA3 nuclear receptor coactivator 3 0.0798623
MED13L mediator complex subunit 13-like 0.0796541
THSD4 thrombospondin, type I, domain containing 4 0.0750544
COL4A5 collagen, type IV, alpha 5 0.0745908
RPS3 ribosomal protein S3 0.0743417
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.0732553
RPLP0 ribosomal protein, large, P0 0.0724045
ZMYND8 zinc finger, MYND-type containing 8 0.0652157
ABHD2 abhydrolase domain containing 2 0.0638176
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 0.0636013
RPL15 ribosomal protein L15 0.0611938
KYNU kynureninase 0.0575395
GFRA1 GDNF family receptor alpha 1 0.0560456
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 0.0557768
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0538805
PRR11 proline rich 11 0.0530809
FOXP1 forkhead box P1 0.052092
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0520419
RPL18 ribosomal protein L18 0.0515638
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.0513211
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.0509111
ADGRG6 adhesion G protein-coupled receptor G6 0.0505099
RHOBTB3 Rho-related BTB domain containing 3 0.0499619
CCND1 cyclin D1 0.0479746
PCED1B PC-esterase domain containing 1B 0.0473714
H3-3B H3.3 histone B 0.0470716
HSPB1 heat shock 27kDa protein 1 0.0465059
CUX1 cut-like homeobox 1 0.0453725
MALRD1 MAM and LDL receptor class A domain containing 1 0.0447235
BCL2 B-cell CLL/lymphoma 2 0.044076
H1-10 H1.10 linker histone 0.0438055
STC2 stanniocalcin 2 0.0429752
LGALS3 lectin, galactoside-binding, soluble, 3 0.042864
DST dystonin 0.0425969
PKM pyruvate kinase, muscle 0.0425829
RPLP1 ribosomal protein, large, P1 0.042409
FGF12 fibroblast growth factor 12 0.0422632
ZFP36L2 ZFP36 ring finger protein-like 2 0.0422137
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0420023
RPS2 ribosomal protein S2 0.0413105
ENSA endosulfine alpha 0.0412859
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.040908
RPL29 ribosomal protein L29 0.0407009
LOC112694756 uncharaterized LOC112694756 0.0403361
SULF2 sulfatase 2 0.0401563
RPL37A ribosomal protein L37a 0.0397057
TPM1 tropomyosin 1 (alpha) 0.0396457
CXXC5 CXXC finger protein 5 0.0392676
ZNF217 zinc finger protein 217 0.0390647
DSTN destrin (actin depolymerizing factor) 0.0389742
DSCAM Down syndrome cell adhesion molecule 0.0383976
RPS18 ribosomal protein S18 0.0383568
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0382863
WIPF1 WAS/WASL interacting protein family, member 1 0.0380888
FLNA filamin A, alpha 0.0375684
TNRC18 trinucleotide repeat containing 18 0.0375624
NEBL nebulette 0.0374256
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0367579
RPL30 ribosomal protein L30 0.036624
PTPRK protein tyrosine phosphatase, receptor type, K 0.0364178
HSF1 heat shock transcription factor 1 0.0357945
VMP1 vacuole membrane protein 1 0.0354448
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 0.0351295
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.0342904
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 0.034255
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.0340053
PAWR PRKC, apoptosis, WT1, regulator 0.0337737
LRPPRC leucine-rich pentatricopeptide repeat containing 0.0334435
RPL10A ribosomal protein L10a 0.0331659
COX5B cytochrome c oxidase subunit Vb 0.0331367
RPL37 ribosomal protein L37 0.0329944
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.0327266
BSG basigin (Ok blood group) 0.0326083
MYO5C myosin VC 0.0322795
RPSA ribosomal protein SA 0.0322772
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.0322426
FXYD3 FXYD domain containing ion transport regulator 3 0.03219
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.0320838
ZCCHC7 zinc finger, CCHC domain containing 7 0.0318694
MRPL13 mitochondrial ribosomal protein L13 0.0317725
CST3 cystatin C 0.0316971
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.0316915
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 0.0316766
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0313109
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.0312299
LRP10 low density lipoprotein receptor-related protein 10 0.0310987
RUNX1 runt-related transcription factor 1 0.0310819
LOC102724023 ES1 protein homolog, mitochondrial 0.0310191
SETX senataxin 0.030674
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.0305007
RAB6A RAB6A, member RAS oncogene family 0.0304074
SDK1 sidekick cell adhesion molecule 1 0.0303671
IGSF1 immunoglobulin superfamily, member 1 0.030294
IQGAP1 IQ motif containing GTPase activating protein 1 0.0301327
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.0297126
VCL vinculin 0.029701
PKN2 protein kinase N2 0.0296605
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 0.0296439
NRP1 neuropilin 1 0.0292621
ATXN7 ataxin 7 0.0291998
RPS23 ribosomal protein S23 0.0291098
TRIM56 tripartite motif containing 56 0.0290513
HEATR6 HEAT repeat containing 6 0.0289977
RPL36 ribosomal protein L36 0.028886
MACC1 metastasis associated in colon cancer 1 0.0285211
CLSTN1 calsyntenin 1 0.0283482
ARSG arylsulfatase G 0.028287
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.0281941
GOLGA4 golgin A4 0.0281291
ENTREP1 endosomal transmembrane epsin interactor 1 0.0280965
OSBPL9 oxysterol binding protein-like 9 0.0279752
BTBD9 BTB (POZ) domain containing 9 0.0279609
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 0.0274976
TTC3 tetratricopeptide repeat domain 3 0.0274552
ATP5F1E ATP synthase F1 subunit epsilon 0.0274483
RPS9 ribosomal protein S9 0.0273883
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0273195
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.0267188
TOB1 transducer of ERBB2, 1 0.0266962
EEF2 eukaryotic translation elongation factor 2 0.0264237
TUBD1 tubulin, delta 1 0.0263623
ARFGEF3 ARFGEF family member 3 0.0263105
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0260911
SLC38A1 solute carrier family 38, member 1 0.0258863
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.0258382
PFDN4 prefoldin subunit 4 0.0257285
ZFAND3 zinc finger, AN1-type domain 3 0.0256106
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.0255069
UBE4B ubiquitination factor E4B 0.025483
SLC38A9 solute carrier family 38, member 9 0.0254527
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0253044
FNDC3A fibronectin type III domain containing 3A 0.0252767
OSBPL8 oxysterol binding protein-like 8 0.0252067
RSF1 remodeling and spacing factor 1 0.025167
GOLGB1 golgin B1 0.0250903
RPL13A ribosomal protein L13a 0.0250769
PCBP2 poly(rC) binding protein 2 0.0249664
RPL7A ribosomal protein L7a 0.0249546
RNF115 ring finger protein 115 0.0249181
WASL Wiskott-Aldrich syndrome-like 0.0247636
SYT1 synaptotagmin I 0.0247499
NONO non-POU domain containing, octamer-binding 0.0247334
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.0246121
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.0245465
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.0242535
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.0242449
SEPTIN9 septin 9 0.0242294
TRIR telomerase RNA component interacting RNase 0.0241941
RPS17 ribosomal protein S17 0.0241874
HELZ helicase with zinc finger 0.0241551
ACTN4 actinin, alpha 4 0.0241023
ZC3H13 zinc finger CCCH-type containing 13 0.0240932
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 0.0240223
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.0239568
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0238686
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0238451
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.023747
HDLBP high density lipoprotein binding protein 0.0237285
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.023574
SYT12 synaptotagmin XII 0.0235016
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.0234707
RAB31 RAB31, member RAS oncogene family 0.0234584
KIAA1217 KIAA1217 0.023438
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.0234346
RPS6 ribosomal protein S6 0.0234163
CAV1 caveolin 1, caveolae protein, 22kDa 0.0233013
PRRC2C proline-rich coiled-coil 2C 0.0232536
RPL27 ribosomal protein L27 0.0228402
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.022612
CDPF1 cysteine-rich, DPF motif domain containing 1 0.0225955
RPL18A ribosomal protein L18a 0.0225069
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.0224405
ECE1 endothelin converting enzyme 1 0.0224328
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.022379
BLTP2 bridge-like lipid transfer protein family member 2 0.0223573
RPS21 ribosomal protein S21 0.0223451
PPCDC phosphopantothenoylcysteine decarboxylase 0.0223196
RPL11 ribosomal protein L11 0.0221868
ZNF451 zinc finger protein 451 0.0221848
ANXA2 annexin A2 0.0221071
RABGAP1L RAB GTPase activating protein 1-like 0.0220151
RACK1 receptor for activated C kinase 1 0.022006
COMMD10 COMM domain containing 10 0.0219899
SYMPK symplekin 0.0219169
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0218999
KRT80 keratin 80, type II 0.0218428
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.0217587
MLEC malectin 0.0217296
RAD23B RAD23 homolog B (S. cerevisiae) 0.0216613
TUG1 taurine up-regulated 1 (non-protein coding) 0.021642
NT5DC3 5'-nucleotidase domain containing 3 0.0213631
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.0213249
MGP matrix Gla protein 0.0212736
PACS1 phosphofurin acidic cluster sorting protein 1 0.0212291
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 0.0212071
CENPE centromere protein E, 312kDa 0.0212069
RASEF RAS and EF-hand domain containing 0.0209978
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 0.0208964
NOTCH2 notch 2 0.0208909
CARM1 coactivator-associated arginine methyltransferase 1 0.0208174
RPS15 ribosomal protein S15 0.0207889
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.0207646
BCAS2 breast carcinoma amplified sequence 2 0.0207013
BABAM2 BRISC and BRCA1 A complex member 2 0.0206503
GLO1 glyoxalase I 0.0206217
ATOX1 antioxidant 1 copper chaperone 0.020583
ACSS3 acyl-CoA synthetase short-chain family member 3 0.0205037
TUFT1 tuftelin 1 0.0204479
YIPF3 Yip1 domain family, member 3 0.020412
LAPTM4B lysosomal protein transmembrane 4 beta 0.0204011
DARS1 aspartyl-tRNA synthetase 1 0.0203934
UBE3D ubiquitin protein ligase E3D 0.0202561
IGFBP5 insulin-like growth factor binding protein 5 0.0201878
CANX calnexin 0.0201462
RPS5 ribosomal protein S5 0.020102
BTN3A3 butyrophilin, subfamily 3, member A3 0.0200704
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.0200332
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.0199533
MYH9 myosin, heavy chain 9, non-muscle 0.0198823
ATRNL1 attractin-like 1 0.0198117
TLK1 tousled-like kinase 1 0.0196976
SOX4 SRY (sex determining region Y)-box 4 0.0196766
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.0196457
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 0.0196279
PA2G4 proliferation-associated 2G4, 38kDa 0.0196047
ZBTB7A zinc finger and BTB domain containing 7A 0.0195929
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0195739
RABL6 RAB, member RAS oncogene family-like 6 0.0194814
PHKB phosphorylase kinase, beta 0.0194653
RPTOR regulatory associated protein of MTOR, complex 1 0.0194597
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 0.019453
CALCR calcitonin receptor 0.0193028
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.0192785
ZNF33B zinc finger protein 33B 0.0192527
IGFBP4 insulin-like growth factor binding protein 4 0.0192269
RPL38 ribosomal protein L38 0.0192077
GPATCH4 G patch domain containing 4 0.0191934
SRRM2 serine/arginine repetitive matrix 2 0.0191674
SPDEF SAM pointed domain containing ETS transcription factor 0.0191499
FASN fatty acid synthase 0.0191306
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.0191053
PTK2 protein tyrosine kinase 2 0.0190658
XRN2 5'-3' exoribonuclease 2 0.0190424
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 0.0189876
POTEF POTE ankyrin domain family, member F 0.0189848
ANAPC5 anaphase promoting complex subunit 5 0.0189237
CD9 CD9 molecule 0.0189023
SEC16A SEC16 homolog A (S. cerevisiae) 0.0188146
PLD3 phospholipase D family, member 3 0.0187938
MRRF mitochondrial ribosome recycling factor 0.0187844
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.0187659
PFN1 profilin 1 0.0186771
TMEM165 transmembrane protein 165 0.0186573
S100A11 S100 calcium binding protein A11 0.0186513
CCN5 cellular communication network factor 5 0.0185321
RSL1D1 ribosomal L1 domain containing 1 0.0184877
CAPN8 calpain 8 0.018486
FXR1 fragile X mental retardation, autosomal homolog 1 0.0184252
NOL8 nucleolar protein 8 0.0184054
CYB561 cytochrome b561 0.0182974
MAP3K2 mitogen-activated protein kinase kinase kinase 2 0.0182675
TMEM154 transmembrane protein 154 0.0182483
FUBP3 far upstream element (FUSE) binding protein 3 0.0182327
LDLR low density lipoprotein receptor 0.0182153
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 0.0182013
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.01819
PTPRF protein tyrosine phosphatase, receptor type, F 0.0181879
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 0.0181757
NFE2L2 nuclear factor, erythroid 2-like 2 0.0181414
UBXN4 UBX domain protein 4 0.0181142
SQLE squalene epoxidase 0.0181134
PICALM phosphatidylinositol binding clathrin assembly protein 0.018013
KRABD5 KRAB domain containing 5 0.0179919
BCL2L1 BCL2-like 1 0.0179898
SMIM44 small integral membrane protein 44 0.0179554
EYA2 EYA transcriptional coactivator and phosphatase 2 0.0179189
RPS7 ribosomal protein S7 0.0179155
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.017869
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) 0.0178367
MAVS mitochondrial antiviral signaling protein 0.0177708
TUBA1C tubulin, alpha 1c 0.0177632
PPP1R13B protein phosphatase 1, regulatory subunit 13B 0.0177045
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa 0.0176914
ZNF609 zinc finger protein 609 0.0176831
SCAMP2 secretory carrier membrane protein 2 0.0176753
ZNF91 zinc finger protein 91 0.0176619
PODXL podocalyxin-like 0.0176521
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0176087
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.0175899
UBL4A ubiquitin-like 4A 0.0175855
LARP4 La ribonucleoprotein domain family, member 4 0.0175733
DNMBP dynamin binding protein 0.0175566
ERP44 endoplasmic reticulum protein 44 0.0175501
ZNF394 zinc finger protein 394 0.0175265
DNM1L dynamin 1-like 0.0175108
IGF1R insulin-like growth factor 1 receptor 0.0174869
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit 0.0174456
UFC1 ubiquitin-fold modifier conjugating enzyme 1 0.0174223
SORT1 sortilin 1 0.0174179
TESK2 testis-specific kinase 2 0.0173407
ANKRD46 ankyrin repeat domain 46 0.0173323
LEPROT leptin receptor overlapping transcript 0.0173033
PARP4 poly (ADP-ribose) polymerase family, member 4 0.0173003
LRRC8B leucine rich repeat containing 8 family, member B 0.0172701
GFUS GDP-L-fucose synthase 0.017251
APOD apolipoprotein D 0.0172181
PHB1 prohibitin 1 0.0172179
PEX26 peroxisomal biogenesis factor 26 0.0172098
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 0.017203
AMZ1 archaelysin family metallopeptidase 1 0.0171936
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0171705
COXFA4 cytochrome c oxidase associated subunit FA4 0.017162
CD59 CD59 molecule, complement regulatory protein 0.0171442
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 0.0169956
MYO1E myosin IE 0.0169603
ACSL3 acyl-CoA synthetase long-chain family member 3 0.0169447
CLPTM1 cleft lip and palate associated transmembrane protein 1 0.0168302
BRCA2 breast cancer 2, early onset 0.0168178
AKAP11 A kinase (PRKA) anchor protein 11 0.0167913
CEP95 centrosomal protein 95kDa 0.016756
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 0.0167362
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 0.0167211
ZNF148 zinc finger protein 148 0.0167173
EEF1B2 eukaryotic translation elongation factor 1 beta 2 0.016675
URI1 URI1, prefoldin-like chaperone 0.0166665
SNX29 sorting nexin 29 0.0166535
EZR ezrin 0.0166509
PDLIM5 PDZ and LIM domain 5 0.0166378
TOMM70 translocase of outer mitochondrial membrane 70 0.0166076
CLTB clathrin, light chain B 0.0166011
RPL3 ribosomal protein L3 0.0165749
TRIM26 tripartite motif containing 26 0.0165558
TMEM160 transmembrane protein 160 0.0164922
SINHCAF SIN3-HDAC complex associated factor 0.0164819
CADM1 cell adhesion molecule 1 0.016481
UBE2Z ubiquitin-conjugating enzyme E2Z 0.016475
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.0164628
GDNF glial cell derived neurotrophic factor 0.0164455
BCAS1 breast carcinoma amplified sequence 1 0.0163995
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 0.0163888
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.0163715
RNFT2 ring finger protein, transmembrane 2 0.0163496
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) 0.0163388
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.0163316
ACTN1 actinin, alpha 1 0.0161982
RPS14 ribosomal protein S14 0.0161931
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 0.0161926
LIN52 lin-52 DREAM MuvB core complex component 0.0161365
SMIM14 small integral membrane protein 14 0.0161283
AURKA aurora kinase A 0.0161123
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 0.0160686
FGF13 fibroblast growth factor 13 0.0160627
KIAA1328 KIAA1328 0.0159875
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 0.0159813
PNPT1 polyribonucleotide nucleotidyltransferase 1 0.0159503
AXIN1 axin 1 0.0158954
RAB22A RAB22A, member RAS oncogene family 0.0157191
LAGE3 L antigen family, member 3 0.0157154
ADISSP adipose secreted signaling protein 0.0156975
WDR59 WD repeat domain 59 0.01569
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.0156642
UBE2G2 ubiquitin-conjugating enzyme E2G 2 0.0156611
GCN1 GCN1 activator of EIF2AK4 0.0156368
UQCRH ubiquinol-cytochrome c reductase hinge protein 0.0155645
ETNK1 ethanolamine kinase 1 0.0155465
FKRP fukutin related protein 0.0155457
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa 0.0155229
C14ORF132 chromosome 14 open reading frame 132 0.0155216
PLIN4 perilipin 4 0.0154998
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.0154985
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 0.0154901
BFAR bifunctional apoptosis regulator 0.0154271
PSD3 pleckstrin and Sec7 domain containing 3 0.0153828
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 0.0153694
SDCCAG8 serologically defined colon cancer antigen 8 0.0153693
RPL31 ribosomal protein L31 0.0153107
GSPT1 G1 to S phase transition 1 0.0153048
PCBD2 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 0.0152906
CLDN7 claudin 7 0.0152823
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 0.0152325
NRDE2 NRDE-2, necessary for RNA interference, domain containing 0.0152263
ACO1 aconitase 1, soluble 0.0152077
NALF1 NALCN channel auxiliary factor 1 0.0152077
CTBP2 C-terminal binding protein 2 0.0152074
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 0.0151935
STARD10 StAR-related lipid transfer (START) domain containing 10 0.0151884
ITGB6 integrin, beta 6 0.0151482
BAG1 BCL2-associated athanogene 0.0151418
MCC mutated in colorectal cancers 0.0151187
GTF2IRD2B GTF2I repeat domain containing 2B 0.0151183
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0151176
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.0151165
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 0.0151008
MLXIP MLX interacting protein 0.0150593
FKBP4 FK506 binding protein 4, 59kDa 0.0150448
YME1L1 YME1-like 1 ATPase 0.0150282
ANAPC11 anaphase promoting complex subunit 11 0.014963
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 0.0149437
ERBB3 erb-b2 receptor tyrosine kinase 3 0.0149258
EIF3E eukaryotic translation initiation factor 3, subunit E 0.0148798
ETF1 eukaryotic translation termination factor 1 0.0148744
RPL19 ribosomal protein L19 0.0148729
MAP2K5 mitogen-activated protein kinase kinase 5 0.0148587
INSIG1 insulin induced gene 1 0.0147966
C6ORF62 chromosome 6 open reading frame 62 0.014783
PRPF8 pre-mRNA processing factor 8 0.0147778
FAM193A family with sequence similarity 193, member A 0.0146192
NINJ1 ninjurin 1 0.0145615
EIF3B eukaryotic translation initiation factor 3, subunit B 0.0145479
JTB jumping translocation breakpoint 0.0145372
TSPAN5 tetraspanin 5 0.0145263
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) 0.0145256
RPL17-C18ORF32 RPL17-C18orf32 readthrough 0.0145225
COBL cordon-bleu WH2 repeat protein 0.0145215
ERCC1 excision repair cross-complementation group 1 0.0144831
IFI27 interferon, alpha-inducible protein 27 0.0144705
MTPAP mitochondrial poly(A) polymerase 0.0144628
PCDHB16 protocadherin beta 16 0.0144605
CRY1 cryptochrome circadian clock 1 0.0144487
SEC24B SEC24 family member B 0.0144195
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 0.0144115
R3HDM2 R3H domain containing 2 0.0144071
NAV2 neuron navigator 2 0.0144012
NACA nascent polypeptide-associated complex alpha subunit 0.0143697
GNA14 guanine nucleotide binding protein (G protein), alpha 14 0.0143428
UBL3 ubiquitin-like 3 0.0143196
SRSF9 serine/arginine-rich splicing factor 9 0.0143008
S100A14 S100 calcium binding protein A14 0.0143008
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 0.0142831
TRAK1 trafficking protein, kinesin binding 1 0.0142662
RNF38 ring finger protein 38 0.0142229
REEP5 receptor accessory protein 5 0.0141746
ITGB1BP1 integrin beta 1 binding protein 1 0.0141439
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.0141436
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.0141207
NUP155 nucleoporin 155kDa 0.0141075
PDE8A phosphodiesterase 8A 0.0140938
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0140895
SUMF1 sulfatase modifying factor 1 0.0140791
GCLC glutamate-cysteine ligase, catalytic subunit 0.0140524
RPS27 ribosomal protein S27 0.0140493
ULK1 unc-51 like autophagy activating kinase 1 0.0140466
PDZRN3 PDZ domain containing ring finger 3 0.0140291
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 0.0140195
PRDM10 PR domain containing 10 0.0140049
RANBP2 RAN binding protein 2 0.0139883
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.0139689
SHB Src homology 2 domain containing adaptor protein B 0.0139276
APRT adenine phosphoribosyltransferase 0.013921
CLDN4 claudin 4 0.0139181
FOS FBJ murine osteosarcoma viral oncogene homolog 0.0139012
ZNF644 zinc finger protein 644 0.013901
UBE2G1 ubiquitin-conjugating enzyme E2G 1 0.0139006
LARS2 leucyl-tRNA synthetase 2, mitochondrial 0.0138727
KMT5B lysine methyltransferase 5B 0.0138574
ARF3 ADP-ribosylation factor 3 0.0138396
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 0.0138319
MECOM MDS1 and EVI1 complex locus 0.0138316
CPEB2 cytoplasmic polyadenylation element binding protein 2 0.0137977
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.0137611
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.0137386
ZBTB44 zinc finger and BTB domain containing 44 0.0137046
TAC4 tachykinin 4 (hemokinin) 0.0137044
HRNR hornerin 0.0136699
JPT1 Jupiter microtubule associated homolog 1 0.0136588
RIC1 RAB6A GEF complex partner 1 0.0136494
RNF24 ring finger protein 24 0.0136403
MFSD1 major facilitator superfamily domain containing 1 0.0136225
GM2A GM2 ganglioside activator 0.0136192
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 0.0136071
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 0.0136015
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.0135672
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.0135162
ATXN3 ataxin 3 0.0134979
EGR1 early growth response 1 0.0134949
ABHD11 abhydrolase domain containing 11 0.0134926
ZNFX1 zinc finger, NFX1-type containing 1 0.0134881
RPS25 ribosomal protein S25 0.0134786
HDGF hepatoma-derived growth factor 0.0134774
EPB41 erythrocyte membrane protein band 4.1 0.0134754
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0134485
AURKAIP1 aurora kinase A interacting protein 1 0.0134419
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 0.0134343
PEAK1 pseudopodium-enriched atypical kinase 1 0.0133963
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0133557
JUND jun D proto-oncogene 0.0133502
DHCR24 24-dehydrocholesterol reductase 0.0133494
SDC4 syndecan 4 0.0133368
AMIGO2 adhesion molecule with Ig-like domain 2 0.0133199
IARS1 isoleucyl-tRNA synthetase 1 0.013312

decreased expression

Symbol Name Standardized Value
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.118347
BCAS3 breast carcinoma amplified sequence 3 -0.115045
WWOX WW domain containing oxidoreductase -0.0941872
GATA3 GATA binding protein 3 -0.0925878
PARD6B par-6 family cell polarity regulator beta -0.0870714
BCAS4 breast carcinoma amplified sequence 4 -0.0858015
EVL Enah/Vasp-like -0.081909
GRHL2 grainyhead-like 2 (Drosophila) -0.0749069
KRT8 keratin 8, type II -0.0692858
MACROD2 MACRO domain containing 2 -0.065717
PTPRG protein tyrosine phosphatase, receptor type, G -0.0562195
SMYD3 SET and MYND domain containing 3 -0.0553704
SKA2 spindle and kinetochore associated complex subunit 2 -0.0550667
PTGES2 prostaglandin E synthase 2 -0.0540607
SPTSSB serine palmitoyltransferase, small subunit B -0.0530368
ATAD2 ATPase family, AAA domain containing 2 -0.0514268
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.0497064
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0493143
ANKRD11 ankyrin repeat domain 11 -0.0483288
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.0462188
LMBR1 limb development membrane protein 1 -0.0457512
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -0.0451833
KRT18 keratin 18, type I -0.0450699
MKI67 marker of proliferation Ki-67 -0.0450369
ESR1 estrogen receptor 1 -0.044967
TMEM64 transmembrane protein 64 -0.0439744
ADCY9 adenylate cyclase 9 -0.0436695
LRP1B low density lipoprotein receptor-related protein 1B -0.0434884
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.0419404
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) -0.0416484
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -0.0410839
BPTF bromodomain PHD finger transcription factor -0.0402872
DCAF7 DDB1 and CUL4 associated factor 7 -0.039615
AREG amphiregulin -0.0394924
CENPP centromere protein P -0.03937
JMJD1C jumonji domain containing 1C -0.0385899
CA12 carbonic anhydrase XII -0.0384289
XBP1 X-box binding protein 1 -0.0383631
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A -0.0381428
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 -0.0375593
PPP6R3 protein phosphatase 6, regulatory subunit 3 -0.0370429
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0361091
CLTC clathrin, heavy chain (Hc) -0.0354179
SLC38A2 solute carrier family 38, member 2 -0.0351429
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.0348745
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 -0.0343681
PUM2 pumilio RNA-binding family member 2 -0.0342301
ASTN2 astrotactin 2 -0.03403
GREB1 growth regulation by estrogen in breast cancer 1 -0.0339659
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.033836
CHD8 chromodomain helicase DNA binding protein 8 -0.0335506
TET2 tet methylcytosine dioxygenase 2 -0.0334949
AGR2 anterior gradient 2 -0.033134
ADCY1 adenylate cyclase 1 (brain) -0.0329198
HIP1 huntingtin interacting protein 1 -0.032736
MED13 mediator complex subunit 13 -0.0326802
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0323634
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0323087
UGCG UDP-glucose ceramide glucosyltransferase -0.0307818
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.0307351
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0306955
NHSL1 NHS-like 1 -0.0306245
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -0.0303732
NEMF nuclear export mediator factor -0.0303502
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0302791
BMP7 bone morphogenetic protein 7 -0.0300713
ZFHX3 zinc finger homeobox 3 -0.0300301
MIS18BP1 MIS18 binding protein 1 -0.0299021
PHF21A PHD finger protein 21A -0.0296105
RNF216 ring finger protein 216 -0.0293201
SF3B3 splicing factor 3b, subunit 3, 130kDa -0.0291535
ATXN1 ataxin 1 -0.0289331
SLF2 SMC5-SMC6 complex localization factor 2 -0.0288378
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0286797
SYTL2 synaptotagmin-like 2 -0.028662
TCF12 transcription factor 12 -0.028653
GIPC1 GIPC PDZ domain containing family, member 1 -0.028508
ILF3 interleukin enhancer binding factor 3, 90kDa -0.0284743
PLCB4 phospholipase C, beta 4 -0.0283349
TUFM Tu translation elongation factor, mitochondrial -0.0282911
CKAP5 cytoskeleton associated protein 5 -0.0280929
SETD1B SET domain containing 1B -0.0280725
FAF1 Fas (TNFRSF6) associated factor 1 -0.0279952
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 -0.0279906
DTD1 D-tyrosyl-tRNA deacylase 1 -0.0278984
FDPS farnesyl diphosphate synthase -0.0278712
SOS1 son of sevenless homolog 1 (Drosophila) -0.027796
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide -0.0276738
ZFR zinc finger RNA binding protein -0.027568
ANKRD17 ankyrin repeat domain 17 -0.0275339
EHMT1 euchromatic histone-lysine N-methyltransferase 1 -0.0274448
FBXO42 F-box protein 42 -0.0273996
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.027264
TANK TRAF family member-associated NFKB activator -0.0272496
ATXN7L1 ataxin 7-like 1 -0.0272362
THOC2 THO complex 2 -0.0272234
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 -0.0271664
RHPN2 rhophilin, Rho GTPase binding protein 2 -0.0269981
CLEC16A C-type lectin domain family 16, member A -0.0269244
APP amyloid beta (A4) precursor protein -0.0267934
NT5C2 5'-nucleotidase, cytosolic II -0.0267794
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein -0.0263447
SENP6 SUMO1/sentrin specific peptidase 6 -0.0261665
KDM6A lysine (K)-specific demethylase 6A -0.0260697
TSEN2 TSEN2 tRNA splicing endonuclease subunit -0.0260383
CYRIB CYFIP related Rac1 interactor B -0.0260326
UGDH UDP-glucose 6-dehydrogenase -0.0259785
SPAG9 sperm associated antigen 9 -0.0259285
MCU mitochondrial calcium uniporter -0.0255589
RAB7A RAB7A, member RAS oncogene family -0.0253305
ABAT 4-aminobutyrate aminotransferase -0.0253253
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -0.0252724
SIPA1L1 signal-induced proliferation-associated 1 like 1 -0.0252097
TLK2 tousled-like kinase 2 -0.0249273
RNGTT RNA guanylyltransferase and 5'-phosphatase -0.0248971
STX8 syntaxin 8 -0.0248177
TRIM33 tripartite motif containing 33 -0.0246954
GPR137C G protein-coupled receptor 137C -0.0246341
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 -0.0245899
SUCO SUN domain containing ossification factor -0.0245687
TENM3 teneurin transmembrane protein 3 -0.024528
ACACA acetyl-CoA carboxylase alpha -0.0244093
MYO6 myosin VI -0.0243113
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B -0.0242942
MYOF myoferlin -0.0241348
CDK6 cyclin-dependent kinase 6 -0.0239828
MICU1 mitochondrial calcium uptake 1 -0.0239121
SLC44A1 solute carrier family 44 (choline transporter), member 1 -0.0239105
WDHD1 WD repeat and HMG-box DNA binding protein 1 -0.0239029
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E -0.0238825
CBX5 chromobox homolog 5 -0.023792
ZNF207 zinc finger protein 207 -0.0237311
MEF2A myocyte enhancer factor 2A -0.0236479
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -0.0234812
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -0.0234698
CHD9 chromodomain helicase DNA binding protein 9 -0.0234605
FBXL17 F-box and leucine-rich repeat protein 17 -0.023392
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0233594
DCDC2 doublecortin domain containing 2 -0.0232584
MAPKAP1 mitogen-activated protein kinase associated protein 1 -0.0232361
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) -0.0231057
NPAS3 neuronal PAS domain protein 3 -0.0230597
RAB11FIP3 RAB11 family interacting protein 3 (class II) -0.0229503
NTN1 netrin 1 -0.0229054
GPHN gephyrin -0.0228711
XPO4 exportin 4 -0.0228477
CAPN7 calpain 7 -0.0228344
TP53 tumor protein p53 -0.0228147
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -0.0227008
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0226958
ZNF398 zinc finger protein 398 -0.0226481
PITPNA phosphatidylinositol transfer protein, alpha -0.022606
TMEM245 transmembrane protein 245 -0.0225166
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 -0.0224804
BRI3BP BRI3 binding protein -0.0223283
RPN2 ribophorin II -0.0222733
TMEM131 transmembrane protein 131 -0.0222102
PCNX1 pecanex 1 -0.0222072
SLC44A2 solute carrier family 44 (choline transporter), member 2 -0.0221783
KMT2C lysine (K)-specific methyltransferase 2C -0.0221615
NCOA6 nuclear receptor coactivator 6 -0.0220688
AGO3 argonaute RISC catalytic component 3 -0.0219954
KAT6A K(lysine) acetyltransferase 6A -0.0219214
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -0.021857
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0218255
MYO9A myosin IXA -0.0218004
CFDP1 craniofacial development protein 1 -0.0217459
ERGIC2 ERGIC and golgi 2 -0.0217269
SND1 staphylococcal nuclease and tudor domain containing 1 -0.0217266
FREM2 FRAS1 related extracellular matrix protein 2 -0.0216644
ITCH itchy E3 ubiquitin protein ligase -0.0216415
FOXK1 forkhead box K1 -0.0216261
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.021613
USP48 ubiquitin specific peptidase 48 -0.021611
SP3 Sp3 transcription factor -0.0215594
POLR1A polymerase (RNA) I polypeptide A, 194kDa -0.0215461
RASA2 RAS p21 protein activator 2 -0.021509
MAN1A2 mannosidase, alpha, class 1A, member 2 -0.0214958
USP15 ubiquitin specific peptidase 15 -0.0214218
PHTF2 putative homeodomain transcription factor 2 -0.0213491
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 -0.0213056
EML5 echinoderm microtubule associated protein like 5 -0.0212661
DTNB dystrobrevin, beta -0.0212622
ZMYM4 zinc finger, MYM-type 4 -0.0212555
STK24 serine/threonine kinase 24 -0.0212228
TASOR2 transcription activation suppressor family member 2 -0.0212061
ZHX2 zinc fingers and homeoboxes 2 -0.0211281
CBX1 chromobox homolog 1 -0.0211142
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -0.0210801
DOP1A DOP1 leucine zipper like protein A -0.0210539
SPTAN1 spectrin, alpha, non-erythrocytic 1 -0.0209951
WASF2 WAS protein family, member 2 -0.0208951
FAM222B family with sequence similarity 222, member B -0.0208905
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 -0.0208181
ABHD18 abhydrolase domain containing 18 -0.0207633
TCERG1 transcription elongation regulator 1 -0.020736
RNASE3 ribonuclease, RNase A family, 3 -0.0207011
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0205797
CCDC47 coiled-coil domain containing 47 -0.0205378
LRMDA leucine rich melanocyte differentiation associated -0.0204567
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.0204405
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.0204031
STK39 serine threonine kinase 39 -0.0204008
HDAC8 histone deacetylase 8 -0.0203266
TPD52L2 tumor protein D52-like 2 -0.0203069
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0203062
PNKP polynucleotide kinase 3'-phosphatase -0.0202872
XXYLT1 xyloside xylosyltransferase 1 -0.0201475
DAAM1 dishevelled associated activator of morphogenesis 1 -0.0201362
MPZ myelin protein zero -0.0200811
PTBP3 polypyrimidine tract binding protein 3 -0.0200785
FANCI Fanconi anemia, complementation group I -0.0200456
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -0.0198216
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 -0.0197349
RGS3 regulator of G-protein signaling 3 -0.0197267
GALC galactosylceramidase -0.0197196
PLXDC2 plexin domain containing 2 -0.0196991
PDIA3 protein disulfide isomerase family A, member 3 -0.0196322
RREB1 ras responsive element binding protein 1 -0.019579
GPATCH2 G patch domain containing 2 -0.0195747
SKIC3 SKI3 subunit of superkiller complex -0.0194245
GLG1 golgi glycoprotein 1 -0.0193955
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0193516
NBPF15 neuroblastoma breakpoint family, member 15 -0.0192965
SSR4 signal sequence receptor, delta -0.0192887
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0191757
PRIM2 primase, DNA, polypeptide 2 (58kDa) -0.019123
KCMF1 potassium channel modulatory factor 1 -0.0190986
DCAKD dephospho-CoA kinase domain containing -0.0190796
LETMD1 LETM1 domain containing 1 -0.0190575
POLK polymerase (DNA directed) kappa -0.0190561
KDM3B lysine (K)-specific demethylase 3B -0.0190094
SYAP1 synapse associated protein 1 -0.0190066
PPP6C protein phosphatase 6, catalytic subunit -0.0190049
ASCC1 activating signal cointegrator 1 complex subunit 1 -0.0189871
PCCB propionyl CoA carboxylase, beta polypeptide -0.0189829
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -0.0188204
EPS15 epidermal growth factor receptor pathway substrate 15 -0.0188005
PTGES3 prostaglandin E synthase 3 (cytosolic) -0.0187674
PHKA2 phosphorylase kinase, alpha 2 (liver) -0.0187102
TPD52L1 tumor protein D52-like 1 -0.0186923
RBM39 RNA binding motif protein 39 -0.0186917
STYXL1 serine/threonine/tyrosine interacting-like 1 -0.0186819
ACVR1 activin A receptor, type I -0.0186102
CEP350 centrosomal protein 350kDa -0.0186012
PCDH7 protocadherin 7 -0.0185318
MACROD1 MACRO domain containing 1 -0.0184548
NCOR1 nuclear receptor corepressor 1 -0.0184522
RNFT1 ring finger protein, transmembrane 1 -0.0183937
NXNL2 nucleoredoxin-like 2 -0.0183241
DOCK6 dedicator of cytokinesis 6 -0.0183049
HPCAL1 hippocalcin-like 1 -0.0182925
DCPH1 damage control phosphatase 1 -0.0182739
KPNB1 karyopherin (importin) beta 1 -0.0181655
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta -0.0181004
GTF2IRD1 GTF2I repeat domain containing 1 -0.0180131
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.0178413
ERCC3 excision repair cross-complementation group 3 -0.0178341
KIAA0319L KIAA0319-like -0.0177747
PSPC1 paraspeckle component 1 -0.0177426
ANAPC1 anaphase promoting complex subunit 1 -0.0177333
SLMAP sarcolemma associated protein -0.0177309
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -0.0177009
KIF5B kinesin family member 5B -0.0176775
RBM15 RNA binding motif protein 15 -0.0176557
CCDC170 coiled-coil domain containing 170 -0.0175994
SEC63 SEC63 homolog (S. cerevisiae) -0.0175923
TRPS1 trichorhinophalangeal syndrome I -0.0175812
DHDDS dehydrodolichyl diphosphate synthase -0.0175761
MAPK1 mitogen-activated protein kinase 1 -0.0175755
KIF20B kinesin family member 20B -0.0175591
MCM3AP minichromosome maintenance complex component 3 associated protein -0.0175422
JARID2 jumonji, AT rich interactive domain 2 -0.0175245
DTNA dystrobrevin, alpha -0.017422
PRELID1 PRELI domain containing 1 -0.0173975
COP1 COP1 E3 ubiquitin ligase -0.017369
TRIO trio Rho guanine nucleotide exchange factor -0.017351
NOL11 nucleolar protein 11 -0.0173437
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0173112
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -0.0172788
CASZ1 castor zinc finger 1 -0.017201
SOS2 son of sevenless homolog 2 (Drosophila) -0.017193
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -0.0171923
NUP205 nucleoporin 205kDa -0.0171911
AGO2 argonaute RISC catalytic component 2 -0.0171495
NGLY1 N-glycanase 1 -0.0171425
SAFB scaffold attachment factor B -0.0170942
RPS8 ribosomal protein S8 -0.0170546
SYNGR2 synaptogyrin 2 -0.0170512
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.0170242
NBEAL1 neurobeachin-like 1 -0.0169774
DICER1 dicer 1, ribonuclease type III -0.0169669
TEX2 testis expressed 2 -0.0169638
PLEKHA7 pleckstrin homology domain containing, family A member 7 -0.0168625
PCGF6 polycomb group ring finger 6 -0.0168599
CCSER1 coiled-coil serine-rich protein 1 -0.0168457
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) -0.0168183
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0167835
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0167701
ESD esterase D -0.0167631
NCKAP5 NCK-associated protein 5 -0.0167398
BTBD7 BTB (POZ) domain containing 7 -0.0167201
KHSRP KH-type splicing regulatory protein -0.0166984
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor -0.0166785
ZNF718 zinc finger protein 718 -0.0166763
ZHX3 zinc fingers and homeoboxes 3 -0.0166135
DAD1 defender against cell death 1 -0.0165952
TSPAN15 tetraspanin 15 -0.0165219
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 -0.0164798
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -0.0164724
KANSL1 KAT8 regulatory NSL complex subunit 1 -0.0164688
MEIS2 Meis homeobox 2 -0.0164448
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -0.0164398
RGS17 regulator of G-protein signaling 17 -0.016435
BBX bobby sox homolog (Drosophila) -0.0164308
MCM9 minichromosome maintenance complex component 9 -0.0164283
AHI1 Abelson helper integration site 1 -0.0164039
KHDC1 KH homology domain containing 1 -0.0163993
NSD2 nuclear receptor binding SET domain protein 2 -0.0163588
FKBP3 FK506 binding protein 3, 25kDa -0.0163384
TMEM178B transmembrane protein 178B -0.016338
RAD18 RAD18 E3 ubiquitin protein ligase -0.0162765
HSCB HscB mitochondrial iron-sulfur cluster co-chaperone -0.016252
CLASP1 cytoplasmic linker associated protein 1 -0.0162126
VAC14 Vac14 homolog (S. cerevisiae) -0.0161959
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -0.0161615
ADAM17 ADAM metallopeptidase domain 17 -0.0161514
MBTPS1 membrane-bound transcription factor peptidase, site 1 -0.0161366
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.0161311
GLUL glutamate-ammonia ligase -0.0160956
INTS8 integrator complex subunit 8 -0.0160929
NRBP1 nuclear receptor binding protein 1 -0.0160636
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 -0.0160636
ZFYVE9 zinc finger, FYVE domain containing 9 -0.0160543
INO80 INO80 complex subunit -0.0160245
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) -0.0159629
TMPO thymopoietin -0.0159585
NBAS neuroblastoma amplified sequence -0.01595
DEPTOR DEP domain containing MTOR-interacting protein -0.0159423
ARHGAP21 Rho GTPase activating protein 21 -0.0159336
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.0159177
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C -0.0158069
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 -0.0157989
EXOC6B exocyst complex component 6B -0.0157855
SMG6 SMG6 nonsense mediated mRNA decay factor -0.0157813
FBP1 fructose-1,6-bisphosphatase 1 -0.0157552
ATG5 autophagy related 5 -0.0157299
MTSS1 metastasis suppressor 1 -0.0157201
ZNF407 zinc finger protein 407 -0.0157121
THRB thyroid hormone receptor, beta -0.0156899
SRSF4 serine/arginine-rich splicing factor 4 -0.0156734
LATS1 large tumor suppressor kinase 1 -0.0156526
LYPD6 LY6/PLAUR domain containing 6 -0.015647
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0156436
ARHGAP32 Rho GTPase activating protein 32 -0.0156369
TMEM65 transmembrane protein 65 -0.0155974
SANBR SANT and BTB domain regulator of CSR -0.0155945
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains -0.0155359
INTS6 integrator complex subunit 6 -0.0155161
PRLR prolactin receptor -0.0155012
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.0154581
LARP1B La ribonucleoprotein domain family, member 1B -0.0154345
SLC39A11 solute carrier family 39, member 11 -0.015426
TTK TTK protein kinase -0.0154238
SRP72 signal recognition particle 72kDa -0.0154079
TUBA1B tubulin, alpha 1b -0.015393
SETD3 SET domain containing 3 -0.0153924
PTBP1 polypyrimidine tract binding protein 1 -0.0153619
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -0.0153533
CRYBG1 crystallin beta-gamma domain containing 1 -0.015253
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 -0.0152434
COL18A1 collagen, type XVIII, alpha 1 -0.0152169
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) -0.0152098
MCM6 minichromosome maintenance complex component 6 -0.0152033
UBE2R2 ubiquitin-conjugating enzyme E2R 2 -0.0152026
RFX7 regulatory factor X, 7 -0.0151924
PBRM1 polybromo 1 -0.0151799
NBEA neurobeachin -0.0151409
DCXR dicarbonyl/L-xylulose reductase -0.0151178
DOCK9 dedicator of cytokinesis 9 -0.0151131
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase -0.0150881
AK3 adenylate kinase 3 -0.0150873
TRAP1 TNF receptor-associated protein 1 -0.0150859
DTNBP1 dystrobrevin binding protein 1 -0.0150463
MAML2 mastermind-like 2 (Drosophila) -0.0150156
RRBP1 ribosome binding protein 1 -0.015002
WDR44 WD repeat domain 44 -0.0150007
IPO9 importin 9 -0.0149985
LMF1 lipase maturation factor 1 -0.0149957
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -0.0149868
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase -0.014963
MAMLD1 mastermind-like domain containing 1 -0.0149189
NLK nemo-like kinase -0.0149076
PRICKLE2 prickle homolog 2 (Drosophila) -0.0148893
MESD mesoderm development LRP chaperone -0.0148216
PRTG protogenin -0.0148056
WDFY3 WD repeat and FYVE domain containing 3 -0.0147682
KMT2D lysine (K)-specific methyltransferase 2D -0.0147559
AUTS2 autism susceptibility candidate 2 -0.0147505
GAN gigaxonin -0.0147488
CCM2 cerebral cavernous malformation 2 -0.0146941
RAD9A RAD9 homolog A (S. pombe) -0.01469
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -0.0146827
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 -0.0146777
CCDC92 coiled-coil domain containing 92 -0.0146668
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -0.0146627
YY1 YY1 transcription factor -0.0146328
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.0145843
CUL5 cullin 5 -0.0145824
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -0.0145693
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -0.0145547
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0145463
TET1 tet methylcytosine dioxygenase 1 -0.0145269
RTN4RL1 reticulon 4 receptor-like 1 -0.0144631
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) -0.0144626
KDM7A lysine (K)-specific demethylase 7A -0.0144499
LMAN2 lectin, mannose-binding 2 -0.0143891
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 -0.0143729
MAST4 microtubule associated serine/threonine kinase family member 4 -0.0143498
DYNC2I2 dynein 2 intermediate chain 2 -0.0142809
KANSL1L KAT8 regulatory NSL complex subunit 1-like -0.0142804
WDR37 WD repeat domain 37 -0.0142786
SLC35E1 solute carrier family 35, member E1 -0.0142772
SON SON DNA binding protein -0.0142759
PRRC2B proline-rich coiled-coil 2B -0.0142398
DOP1B DOP1 leucine zipper like protein B -0.0142315
HNRNPF heterogeneous nuclear ribonucleoprotein F -0.0142211
TRAPPC10 trafficking protein particle complex 10 -0.0142069
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 -0.0141955
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) -0.0141814
D2HGDH D-2-hydroxyglutarate dehydrogenase -0.0141456
C6ORF141 chromosome 6 open reading frame 141 -0.014086
TMEM41A transmembrane protein 41A -0.0140418
PUM1 pumilio RNA-binding family member 1 -0.0140274
PTCD3 pentatricopeptide repeat domain 3 -0.0140166
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 -0.0140138
TAOK1 TAO kinase 1 -0.0140057
COG5 component of oligomeric golgi complex 5 -0.013968
BCL9L B-cell CLL/lymphoma 9-like -0.013967
MAST3 microtubule associated serine/threonine kinase 3 -0.0139577
TTF1 transcription termination factor, RNA polymerase I -0.0139402
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 -0.0139363
ATP11B ATPase, class VI, type 11B -0.0139256
FOXM1 forkhead box M1 -0.0139175
PDIA6 protein disulfide isomerase family A, member 6 -0.0139093
CALCOCO2 calcium binding and coiled-coil domain 2 -0.0138945
RERE arginine-glutamic acid dipeptide (RE) repeats -0.0138936
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -0.013873
CIP2A cellular inhibitor of PP2A -0.0138632
CEP104 centrosomal protein 104kDa -0.0138585
FRYL FRY-like -0.0138548
SCYL3 SCY1-like 3 (S. cerevisiae) -0.0138431
CDK17 cyclin-dependent kinase 17 -0.0138419
SPATA7 spermatogenesis associated 7 -0.01384
COPB1 coatomer protein complex, subunit beta 1 -0.0138357
PLK2 polo-like kinase 2 -0.0138091
TMEM192 transmembrane protein 192 -0.0138062
KIF22 kinesin family member 22 -0.0137887
RAB10 RAB10, member RAS oncogene family -0.0137868
PRDM4 PR domain containing 4 -0.0137782
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -0.0137734
LCORL ligand dependent nuclear receptor corepressor-like -0.0137559
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) -0.0137436
WDPCP WD repeat containing planar cell polarity effector -0.0137166
RBM5 RNA binding motif protein 5 -0.0137027
PGRMC1 progesterone receptor membrane component 1 -0.0136956
IQCB1 IQ motif containing B1 -0.0136692
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -0.0136346
GIGYF2 GRB10 interacting GYF protein 2 -0.0136214
DENND5B DENN/MADD domain containing 5B -0.0136167
CADPS2 Ca++-dependent secretion activator 2 -0.0136071
XPOT exportin, tRNA -0.0135869
WDR47 WD repeat domain 47 -0.0135608
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -0.0135434
RNF139 ring finger protein 139 -0.0135383
MAGT1 magnesium transporter 1 -0.0134446
CD47 CD47 molecule -0.0134419
DEPDC1B DEP domain containing 1B -0.0134239
TMX1 thioredoxin-related transmembrane protein 1 -0.0134087
CPEB3 cytoplasmic polyadenylation element binding protein 3 -0.0133692
ZNF367 zinc finger protein 367 -0.013367
SMC4 structural maintenance of chromosomes 4 -0.0133666
WDR20 WD repeat domain 20 -0.0133616
UNK unkempt family zinc finger -0.0133555
SEC11A SEC11 homolog A (S. cerevisiae) -0.0133553
SYNJ2 synaptojanin 2 -0.013349
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -0.0133362
ORC4 origin recognition complex, subunit 4 -0.0132817
RPS13 ribosomal protein S13 -0.0132344
PRPF3 pre-mRNA processing factor 3 -0.0132201
WDR27 WD repeat domain 27 -0.0131914
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -0.0131776
LIMK2 LIM domain kinase 2 -0.0131731
GALK1 galactokinase 1 -0.0131702
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0131537
GFOD1 glucose-fructose oxidoreductase domain containing 1 -0.0131464
HELLS helicase, lymphoid-specific -0.0131321
MB21D2 Mab-21 domain containing 2 -0.0131308
AOPEP aminopeptidase O (putative) -0.013121
RAD51B RAD51 paralog B -0.0131172