MCF7_GSK J1_10µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description GSK J1 10µM perturbation in MCF7 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the MCF7_GSK J1_10µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
IGFBP5 insulin-like growth factor binding protein 5 0.170198
EMP2 epithelial membrane protein 2 0.106148
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.104034
ESR1 estrogen receptor 1 0.0940679
PACS1 phosphofurin acidic cluster sorting protein 1 0.0865072
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.0835314
SULF2 sulfatase 2 0.080213
ABHD2 abhydrolase domain containing 2 0.0741717
PATJ PATJ crumbs cell polarity complex component 0.0734781
VMP1 vacuole membrane protein 1 0.0724884
PARD6B par-6 family cell polarity regulator beta 0.0721672
FLNB filamin B, beta 0.0680826
GATA3 GATA binding protein 3 0.0674873
ELOF1 elongation factor 1 homolog (S. cerevisiae) 0.06509
JARID2 jumonji, AT rich interactive domain 2 0.062139
CTSD cathepsin D 0.0602818
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.0588723
MALRD1 MAM and LDL receptor class A domain containing 1 0.0579871
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 0.0574938
RPL37A ribosomal protein L37a 0.0567338
UGDH UDP-glucose 6-dehydrogenase 0.0563306
LARP1 La ribonucleoprotein domain family, member 1 0.0503815
MSI2 musashi RNA-binding protein 2 0.0487908
TRIM37 tripartite motif containing 37 0.0486218
AHCYL2 adenosylhomocysteinase-like 2 0.0484191
MYOF myoferlin 0.0483201
UBE2H ubiquitin-conjugating enzyme E2H 0.0483006
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 0.0465038
TPM4 tropomyosin 4 0.0459182
CNKSR3 CNKSR family member 3 0.0458964
KDM5B lysine (K)-specific demethylase 5B 0.0453195
CDV3 CDV3 homolog (mouse) 0.0449151
FREM2 FRAS1 related extracellular matrix protein 2 0.0448421
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0447332
DNMBP dynamin binding protein 0.0442777
TNRC18 trinucleotide repeat containing 18 0.042446
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 0.0418498
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.0416341
IGF1R insulin-like growth factor 1 receptor 0.0396573
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0388112
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0387754
STC2 stanniocalcin 2 0.0383388
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.0374713
RPS17 ribosomal protein S17 0.0366581
RAD51B RAD51 paralog B 0.0364382
CLTC clathrin, heavy chain (Hc) 0.036338
WWP1 WW domain containing E3 ubiquitin protein ligase 1 0.036223
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.0357187
UBE4A ubiquitination factor E4A 0.0355786
GOLGB1 golgin B1 0.0354687
MYH9 myosin, heavy chain 9, non-muscle 0.0351364
TSC22D2 TSC22 domain family, member 2 0.0347884
SPTSSB serine palmitoyltransferase, small subunit B 0.0346705
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.0346545
JAK1 Janus kinase 1 0.0345171
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.0339179
TRIM33 tripartite motif containing 33 0.033551
AOPEP aminopeptidase O (putative) 0.0335046
EEIG1 estrogen-induced osteoclastogenesis regulator 1 0.0332465
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 0.032543
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 0.0323771
ANO10 anoctamin 10 0.0322677
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.0321125
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0320812
MARK3 MAP/microtubule affinity-regulating kinase 3 0.0318709
XBP1 X-box binding protein 1 0.0317024
ZSWIM6 zinc finger, SWIM-type containing 6 0.0314433
SMIM14 small integral membrane protein 14 0.0313964
SESTD1 SEC14 and spectrin domains 1 0.031222
CHD9 chromodomain helicase DNA binding protein 9 0.0312168
GRHL2 grainyhead-like 2 (Drosophila) 0.0311361
ZMYND8 zinc finger, MYND-type containing 8 0.0308462
C14ORF132 chromosome 14 open reading frame 132 0.0305037
NRCAM neuronal cell adhesion molecule 0.0304788
NOTCH3 notch 3 0.0304421
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.0301683
BRWD1 bromodomain and WD repeat domain containing 1 0.0301029
VAV2 vav 2 guanine nucleotide exchange factor 0.0300551
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.0300106
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.0298918
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 0.0296659
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.0296522
THBS1 thrombospondin 1 0.0296194
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 0.0295483
SFXN2 sideroflexin 2 0.0292724
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 0.0290203
LURAP1L leucine rich adaptor protein 1-like 0.0287921
PXDN peroxidasin 0.0284349
MACF1 microtubule-actin crosslinking factor 1 0.0282668
NBEA neurobeachin 0.0281446
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0281258
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.0280763
TAOK3 TAO kinase 3 0.0280521
FLNA filamin A, alpha 0.0279711
DSPP dentin sialophosphoprotein 0.0279319
CALCR calcitonin receptor 0.0278765
ELP2 elongator acetyltransferase complex subunit 2 0.0277349
MYO9A myosin IXA 0.0275735
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 0.0275637
NAV1 neuron navigator 1 0.0275484
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.0275118
SMAD3 SMAD family member 3 0.0274115
MAML3 mastermind-like 3 (Drosophila) 0.0273352
CAPZB capping protein (actin filament) muscle Z-line, beta 0.0272729
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.0272654
AHNAK AHNAK nucleoprotein 0.0272563
CCDC47 coiled-coil domain containing 47 0.0271812
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 0.0269835
DYM dymeclin 0.0268093
KAT6B K(lysine) acetyltransferase 6B 0.0266146
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.0265336
SAMD12 sterile alpha motif domain containing 12 0.0264369
ALCAM activated leukocyte cell adhesion molecule 0.026399
SPOPL speckle-type POZ protein-like 0.0262136
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.0261975
SNX29 sorting nexin 29 0.0261496
LGALS3 lectin, galactoside-binding, soluble, 3 0.0260368
PRKCH protein kinase C, eta 0.0257917
CTBP2 C-terminal binding protein 2 0.0257666
ETFA electron-transfer-flavoprotein, alpha polypeptide 0.0255138
GNA14 guanine nucleotide binding protein (G protein), alpha 14 0.0253284
SPG11 spastic paraplegia 11 (autosomal recessive) 0.0251123
PERP PERP, TP53 apoptosis effector 0.0249475
METTL16 methyltransferase like 16 0.0248853
CDPF1 cysteine-rich, DPF motif domain containing 1 0.024801
PBX3 pre-B-cell leukemia homeobox 3 0.0247358
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0246791
ITPRID2 ITPR interacting domain containing 2 0.0245917
NXNL2 nucleoredoxin-like 2 0.024579
COG5 component of oligomeric golgi complex 5 0.0245667
MAGT1 magnesium transporter 1 0.0243433
PDCD7 programmed cell death 7 0.0243141
RPLP1 ribosomal protein, large, P1 0.0241313
CALR calreticulin 0.0241265
MLPH melanophilin 0.0240391
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 0.023997
MYO16 myosin XVI 0.0239861
PDS5B PDS5 cohesin associated factor B 0.0238841
AFF1 AF4/FMR2 family, member 1 0.0238398
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0238213
LRP10 low density lipoprotein receptor-related protein 10 0.0237619
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0235722
TMEM87B transmembrane protein 87B 0.023564
FXYD3 FXYD domain containing ion transport regulator 3 0.0234519
TRAPPC12 trafficking protein particle complex 12 0.0233728
ELF2 E74-like factor 2 (ets domain transcription factor) 0.0233212
RBM33 RNA binding motif protein 33 0.0232612
GLCCI1 glucocorticoid induced 1 0.0231383
ADGRA3 adhesion G protein-coupled receptor A3 0.0231344
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.0230717
ARFGEF3 ARFGEF family member 3 0.0229816
SLC38A2 solute carrier family 38, member 2 0.0228805
FHIP1A FHF complex subunit HOOK interacting protein 1A 0.0227271
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3 0.022697
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 0.0226851
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.0225768
JUP junction plakoglobin 0.0225571
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.0225398
UBL4A ubiquitin-like 4A 0.0224314
CLSTN1 calsyntenin 1 0.0223401
CMTM4 CKLF-like MARVEL transmembrane domain containing 4 0.0223012
RFX3 regulatory factor X, 3 (influences HLA class II expression) 0.0222939
LGALS12 lectin, galactoside-binding, soluble, 12 0.0222679
PDZD8 PDZ domain containing 8 0.0221837
AREG amphiregulin 0.0220289
MARCHF1 membrane associated ring-CH-type finger 1 0.0219734
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 0.0219668
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 0.0219221
RPL13A ribosomal protein L13a 0.0219079
WWTR1 WW domain containing transcription regulator 1 0.0218576
SBNO1 strawberry notch homolog 1 (Drosophila) 0.0218109
SPDEF SAM pointed domain containing ETS transcription factor 0.0217962
RPL39 ribosomal protein L39 0.0216445
RNASE12 ribonuclease, RNase A family, 12 (non-active) 0.02161
EZR ezrin 0.0214935
PLXDC2 plexin domain containing 2 0.0214562
EMCN endomucin 0.0214527
SNED1 sushi, nidogen and EGF-like domains 1 0.0214341
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0214309
GFRA1 GDNF family receptor alpha 1 0.021365
HDAC8 histone deacetylase 8 0.0213502
MYO1E myosin IE 0.0213357
SNX27 sorting nexin family member 27 0.0213076
RPL38 ribosomal protein L38 0.0212558
CASZ1 castor zinc finger 1 0.0212214
MRTFB myocardin related transcription factor B 0.0211411
ITGAV integrin, alpha V 0.0211126
DSTN destrin (actin depolymerizing factor) 0.0210532
PRKCE protein kinase C, epsilon 0.021052
EPB41L5 erythrocyte membrane protein band 4.1 like 5 0.0210464
OSBPL1A oxysterol binding protein-like 1A 0.0210266
AKAP10 A kinase (PRKA) anchor protein 10 0.0210137
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 0.0209503
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 0.0209385
COX5B cytochrome c oxidase subunit Vb 0.0209225
HYOU1 hypoxia up-regulated 1 0.0208658
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 0.0207976
FASN fatty acid synthase 0.0207872
SEPTIN9 septin 9 0.0207731
ESYT1 extended synaptotagmin-like protein 1 0.0207472
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.0207001
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like 0.0206511
SUSD6 sushi domain containing 6 0.0206043
DAND5 DAN domain family member 5, BMP antagonist 0.0204994
ITM2B integral membrane protein 2B 0.0204294
FHIT fragile histidine triad 0.0204209
CHKA choline kinase alpha 0.0204207
PTPRF protein tyrosine phosphatase, receptor type, F 0.0204151
ABI1 abl-interactor 1 0.0203515
MFSD11 major facilitator superfamily domain containing 11 0.0203272
SHISA5 shisa family member 5 0.0203189
UBXN4 UBX domain protein 4 0.0203122
RBM25 RNA binding motif protein 25 0.0202706
METTL15 methyltransferase like 15 0.0201273
EPS15 epidermal growth factor receptor pathway substrate 15 0.0201183
PPP6C protein phosphatase 6, catalytic subunit 0.0199742
ARHGAP32 Rho GTPase activating protein 32 0.0199499
WASL Wiskott-Aldrich syndrome-like 0.019925
MICU2 mitochondrial calcium uptake 2 0.0198906
DMAC2L distal membrane arm assembly component 2 like 0.0198851
TSPAN12 tetraspanin 12 0.0198157
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.0197934
RHOC ras homolog family member C 0.0197888
PPP1R13B protein phosphatase 1, regulatory subunit 13B 0.0197752
CCND3 cyclin D3 0.0196579
CERT1 ceramide transporter 1 0.0196343
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.019626
DOCK6 dedicator of cytokinesis 6 0.0196202
DSCAM Down syndrome cell adhesion molecule 0.0196072
ZHX3 zinc fingers and homeoboxes 3 0.0195958
RPS27 ribosomal protein S27 0.0195708
UGCG UDP-glucose ceramide glucosyltransferase 0.0194838
UQCRH ubiquinol-cytochrome c reductase hinge protein 0.0194801
KDM6A lysine (K)-specific demethylase 6A 0.0194662
MECOM MDS1 and EVI1 complex locus 0.0194478
KRT18 keratin 18, type I 0.0193791
CST3 cystatin C 0.0192972
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.0192962
HM13 histocompatibility (minor) 13 0.0192553
MED12 mediator complex subunit 12 0.0192404
CAB39 calcium binding protein 39 0.0191988
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.0191849
HOOK2 hook microtubule-tethering protein 2 0.0191765
TUBA1B tubulin, alpha 1b 0.0191489
NBEAL1 neurobeachin-like 1 0.019125
CDK19 cyclin-dependent kinase 19 0.0191117
ELOVL2 ELOVL fatty acid elongase 2 0.0190753
SRPK2 SRSF protein kinase 2 0.0190107
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.0189737
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.0189138
SINHCAF SIN3-HDAC complex associated factor 0.018909
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.0188541
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.0188527
ZFHX3 zinc finger homeobox 3 0.0188517
BLTP2 bridge-like lipid transfer protein family member 2 0.0187685
MYL12B myosin, light chain 12B, regulatory 0.0187477
ADCY1 adenylate cyclase 1 (brain) 0.0187456
IRS1 insulin receptor substrate 1 0.0186232
EPCAM epithelial cell adhesion molecule 0.0185998
RAB29 RAB29, member RAS oncogene family 0.0185637
SLC38A10 solute carrier family 38, member 10 0.0185372
GOLGA8B golgin A8 family, member B 0.0185099
VSIG10 V-set and immunoglobulin domain containing 10 0.0185054
GTF2A1 general transcription factor IIA, 1, 19/37kDa 0.0185025
DOCK5 dedicator of cytokinesis 5 0.018482
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 0.0184753
GPBP1 GC-rich promoter binding protein 1 0.0183671
WDR37 WD repeat domain 37 0.0183566
RBM14-RBM4 RBM14-RBM4 readthrough 0.0183082
NEMF nuclear export mediator factor 0.0182988
GNAS GNAS complex locus 0.01827
MACROD2 MACRO domain containing 2 0.0182651
LMF1 lipase maturation factor 1 0.018263
UBN1 ubinuclein 1 0.0182584
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.018133
ARHGAP12 Rho GTPase activating protein 12 0.0180721
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0180203
RGS6 regulator of G-protein signaling 6 0.0179931
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.0179639
EIF5B eukaryotic translation initiation factor 5B 0.0179452
SH3GLB2 SH3-domain GRB2-like endophilin B2 0.017876
ZNF331 zinc finger protein 331 0.0178655
CNPY2 canopy FGF signaling regulator 2 0.0178603
RPL29 ribosomal protein L29 0.017831
GRN granulin 0.0177239
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 0.0177182
MBTD1 mbt domain containing 1 0.0176057
RPS9 ribosomal protein S9 0.017575
ATL2 atlastin GTPase 2 0.0175584
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.0173918
ADIPOR2 adiponectin receptor 2 0.0173689
CERS6 ceramide synthase 6 0.0173624
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 0.0173508
QPCTL glutaminyl-peptide cyclotransferase-like 0.0173477
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0173386
EIF3H eukaryotic translation initiation factor 3, subunit H 0.0172724
CLDN4 claudin 4 0.0172579
SNX14 sorting nexin 14 0.0172274
TPD52L1 tumor protein D52-like 1 0.0172146
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0172047
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 0.0171572
RPS29 ribosomal protein S29 0.0171157
AMBRA1 autophagy/beclin-1 regulator 1 0.0171053
KDM4C lysine (K)-specific demethylase 4C 0.0168985
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0168786
PARD3B par-3 family cell polarity regulator beta 0.0168565
HLA-E major histocompatibility complex, class I, E 0.0167995
TOB1 transducer of ERBB2, 1 0.0167984
SCARB1 scavenger receptor class B, member 1 0.016775
POC1B POC1 centriolar protein B 0.0167662
DCPH1 damage control phosphatase 1 0.0167526
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 0.0167386
RPL12 ribosomal protein L12 0.0167274
MAVS mitochondrial antiviral signaling protein 0.0166658
ACTN4 actinin, alpha 4 0.0166491
NPDC1 neural proliferation, differentiation and control, 1 0.0166458
SCAF11 SR-related CTD-associated factor 11 0.0166207
RHPN2 rhophilin, Rho GTPase binding protein 2 0.0166105
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.0165955
DET1 de-etiolated homolog 1 (Arabidopsis) 0.0164702
PER2 period circadian clock 2 0.0164458
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 0.016407
RNF150 ring finger protein 150 0.0163939
USP15 ubiquitin specific peptidase 15 0.0163611
CLDN7 claudin 7 0.0163566
BICDL1 BICD family like cargo adaptor 1 0.0163559
ACTN1 actinin, alpha 1 0.0163465
IRF2BPL interferon regulatory factor 2 binding protein-like 0.0163083
USP34 ubiquitin specific peptidase 34 0.0162923
GINM1 glycoprotein integral membrane 1 0.0162656
INHBA inhibin, beta A 0.0162471
FAM91A1 family with sequence similarity 91, member A1 0.0162131
ZNF721 zinc finger protein 721 0.016206
TBC1D12 TBC1 domain family, member 12 0.0161715
SUMO2 small ubiquitin-like modifier 2 0.0161653
MBD5 methyl-CpG binding domain protein 5 0.0161611
JAK2 Janus kinase 2 0.0161179
OSBPL2 oxysterol binding protein-like 2 0.0160906
H2AC6 H2A clustered histone 6 0.0160891
RPL23 ribosomal protein L23 0.0160603
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 0.01603
GLRA3 glycine receptor, alpha 3 0.0160237
FAM107B family with sequence similarity 107, member B 0.0160203
SNX24 sorting nexin 24 0.0159338
SSBP3 single stranded DNA binding protein 3 0.0159128
SLC35F5 solute carrier family 35, member F5 0.0158698
VDAC2 voltage-dependent anion channel 2 0.015868
USP3 ubiquitin specific peptidase 3 0.0158301
HRNR hornerin 0.0157769
USP42 ubiquitin specific peptidase 42 0.015772
TMEM132A transmembrane protein 132A 0.0157682
DUSP16 dual specificity phosphatase 16 0.0157545
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.0157272
EAPP E2F-associated phosphoprotein 0.0156652
KRABD5 KRAB domain containing 5 0.0155872
CYB561 cytochrome b561 0.0155653
ERBIN erbb2 interacting protein 0.0155604
OCLN occludin 0.0155488
GREB1L growth regulation by estrogen in breast cancer-like 0.0155461
TRIO trio Rho guanine nucleotide exchange factor 0.0155289
RINT1 RAD50 interactor 1 0.0154883
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 0.0154852
MAP3K21 mitogen-activated protein kinase kinase kinase 21 0.0154299
CERCAM cerebral endothelial cell adhesion molecule 0.015417
ZNF75D zinc finger protein 75D 0.0153802
NRF1 nuclear respiratory factor 1 0.0153636
PEX13 peroxisomal biogenesis factor 13 0.0153518
HSBP1 heat shock factor binding protein 1 0.0153402
HS3ST5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5 0.0153187
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 0.0153087
ECPAS Ecm29 proteasome adaptor and scaffold 0.0152001
HELZ helicase with zinc finger 0.0151956
SET SET nuclear proto-oncogene 0.0151263
RPL18A ribosomal protein L18a 0.0151131
RORA RAR-related orphan receptor A 0.0151107
AEBP2 AE binding protein 2 0.0151073
SEC23IP SEC23 interacting protein 0.0151027
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.0150806
KHDC4 KH domain containing 4, pre-mRNA splicing factor 0.0150366
LUC7L LUC7-like (S. cerevisiae) 0.0150331
OSGEP O-sialoglycoprotein endopeptidase 0.014966
RAB10 RAB10, member RAS oncogene family 0.0149507
MCL1 myeloid cell leukemia 1 0.0149075
CCDC186 coiled-coil domain containing 186 0.0148773
ATRNL1 attractin-like 1 0.0148659
NIPAL1 NIPA-like domain containing 1 0.0148494
C1ORF21 chromosome 1 open reading frame 21 0.0148478
AGR3 anterior gradient 3 0.0148403
ZDHHC7 zinc finger, DHHC-type containing 7 0.014838
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.0147537
NECTIN2 nectin cell adhesion molecule 2 0.0147308
CBR4 carbonyl reductase 4 0.0147116
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0146968
TOGARAM1 TOG array regulator of axonemal microtubules 1 0.0146891
ATP13A1 ATPase type 13A1 0.0146787
WDR41 WD repeat domain 41 0.0146712
SSH1 slingshot protein phosphatase 1 0.0146413
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 0.0146385
N4BP3 NEDD4 binding protein 3 0.0146377
TAPBP TAP binding protein (tapasin) 0.0146211
PKN1 protein kinase N1 0.0146087
CAND1 cullin-associated and neddylation-dissociated 1 0.0145946
MLH3 mutL homolog 3 0.0145718
DNAJC27 DnaJ (Hsp40) homolog, subfamily C, member 27 0.0145615
UBA2 ubiquitin-like modifier activating enzyme 2 0.0145533
PPP1R12B protein phosphatase 1, regulatory subunit 12B 0.0145337
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 0.0144971
GAPVD1 GTPase activating protein and VPS9 domains 1 0.0144916
TMEM64 transmembrane protein 64 0.0144809
SLC44A2 solute carrier family 44 (choline transporter), member 2 0.0143962
PARP4 poly (ADP-ribose) polymerase family, member 4 0.0143934
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 0.014387
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.0143184
ZCCHC7 zinc finger, CCHC domain containing 7 0.0143022
ATP11A ATPase, class VI, type 11A 0.0142899
FTH1 ferritin, heavy polypeptide 1 0.0142655
BCAP31 B-cell receptor-associated protein 31 0.0142595
CCNL1 cyclin L1 0.0142
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 0.0141995
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase 0.0141976
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0141974
QRICH1 glutamine-rich 1 0.0141744
ZDHHC21 zinc finger, DHHC-type containing 21 0.0141667
BCL2L13 BCL2-like 13 (apoptosis facilitator) 0.014153
KIDINS220 kinase D-interacting substrate, 220kDa 0.0141462
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.0141432
ZNF644 zinc finger protein 644 0.0141323
TUFT1 tuftelin 1 0.014126
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.0140832
SPTBN2 spectrin, beta, non-erythrocytic 2 0.0140793
INTS3 integrator complex subunit 3 0.0140759
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0140639
SIPA1L3 signal-induced proliferation-associated 1 like 3 0.0140564
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 0.0140416
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 0.0140263
KRT80 keratin 80, type II 0.0140115
ZMYM2 zinc finger, MYM-type 2 0.0140055
MAST4 microtubule associated serine/threonine kinase family member 4 0.013998
MAP2K5 mitogen-activated protein kinase kinase 5 0.0139623
APTX aprataxin 0.0139445
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor 0.0139009
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.013899
SSBP1 single-stranded DNA binding protein 1, mitochondrial 0.013884
TMEM165 transmembrane protein 165 0.0138668
PRR14L proline rich 14-like 0.0138594
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.0138445
ERCC6L2 excision repair cross-complementation group 6-like 2 0.0138143
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.0137998
XRN2 5'-3' exoribonuclease 2 0.0137957
PKP4 plakophilin 4 0.0137761
AZIN1 antizyme inhibitor 1 0.0137673
NPAS2 neuronal PAS domain protein 2 0.0137184
AHCYL1 adenosylhomocysteinase-like 1 0.0137161
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 0.0137105
MREG melanoregulin 0.0137058
EHMT2 euchromatic histone-lysine N-methyltransferase 2 0.013705
LNX2 ligand of numb-protein X 2 0.0136707
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.0136696
WDR33 WD repeat domain 33 0.013661
SDC4 syndecan 4 0.0136544
CD151 CD151 molecule (Raph blood group) 0.0136536
SEZ6L2 seizure related 6 homolog (mouse)-like 2 0.0136382
ARPC4-TTLL3 ARPC4-TTLL3 readthrough 0.0136052
DCTN1 dynactin 1 0.0136023
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.0135888
UQCRC1 ubiquinol-cytochrome c reductase core protein I 0.0135818
SPNS1 spinster homolog 1 (Drosophila) 0.0135701
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) 0.0135582
RPP38 ribonuclease P/MRP 38kDa subunit 0.0134927
TBC1D22A TBC1 domain family, member 22A 0.0134851
GPBP1L1 GC-rich promoter binding protein 1-like 1 0.0134776
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 0.0134537
HOMER1 homer scaffolding protein 1 0.0134504
TIMP1 TIMP metallopeptidase inhibitor 1 0.0134202
DOCK7 dedicator of cytokinesis 7 0.0133762
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 0.0133745
LARP4 La ribonucleoprotein domain family, member 4 0.0133574
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.0133569
ARHGAP18 Rho GTPase activating protein 18 0.0133469
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0133205
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0133062
PRDM10 PR domain containing 10 0.0132987
LINS1 lines homolog 1 0.013266
ADGRL1 adhesion G protein-coupled receptor L1 0.0132521
TBC1D15 TBC1 domain family, member 15 0.0132462
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 0.0132429
MYDGF myeloid-derived growth factor 0.0132407
TCTN3 tectonic family member 3 0.0132385
NRIP1 nuclear receptor interacting protein 1 0.0132009
CMYA5 cardiomyopathy associated 5 0.0131991
COXFA4 cytochrome c oxidase associated subunit FA4 0.0131614
CTSH cathepsin H 0.0131466
GTF2IRD1 GTF2I repeat domain containing 1 0.0131114
EXOC6 exocyst complex component 6 0.0130886
SYMPK symplekin 0.0130736
DERL1 derlin 1 0.0130662
SNX2 sorting nexin 2 0.0130572
ENTREP1 endosomal transmembrane epsin interactor 1 0.0130562
ZFC3H1 zinc finger, C3H1-type containing 0.0130515
KAT6A K(lysine) acetyltransferase 6A 0.0130483

decreased expression

Symbol Name Standardized Value
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.147537
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.134239
BCAS3 breast carcinoma amplified sequence 3 -0.1101
TFF1 trefoil factor 1 -0.106103
MED13L mediator complex subunit 13-like -0.104643
ERBB4 erb-b2 receptor tyrosine kinase 4 -0.093934
BMP7 bone morphogenetic protein 7 -0.0893628
CUX1 cut-like homeobox 1 -0.081346
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.0785214
H3-3B H3.3 histone B -0.0765724
USP32 ubiquitin specific peptidase 32 -0.0672591
GSE1 Gse1 coiled-coil protein -0.0671843
IFI6 interferon, alpha-inducible protein 6 -0.0665592
GLG1 golgi glycoprotein 1 -0.0661675
CTNND2 catenin (cadherin-associated protein), delta 2 -0.064614
SYTL2 synaptotagmin-like 2 -0.059666
MRPL13 mitochondrial ribosomal protein L13 -0.0578965
RPS6 ribosomal protein S6 -0.0528512
AGR2 anterior gradient 2 -0.0501961
NPAS3 neuronal PAS domain protein 3 -0.0499084
NCAM2 neural cell adhesion molecule 2 -0.0498644
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -0.047742
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.0476227
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0460713
PUS7 pseudouridylate synthase 7 (putative) -0.0449801
IQGAP1 IQ motif containing GTPase activating protein 1 -0.0446394
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 -0.044637
PRR11 proline rich 11 -0.0417742
WWOX WW domain containing oxidoreductase -0.0409691
IFITM3 interferon induced transmembrane protein 3 -0.0408513
ACTG1 actin gamma 1 -0.0407503
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0403178
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 -0.0403155
COL4A5 collagen, type IV, alpha 5 -0.0402265
AK1 adenylate kinase 1 -0.0402233
SDK1 sidekick cell adhesion molecule 1 -0.039989
SACK1B scaffolding CK1 anchoring protein B -0.0386356
TENM3 teneurin transmembrane protein 3 -0.0374176
BIRC6 baculoviral IAP repeat containing 6 -0.0374043
GPC6 glypican 6 -0.0371068
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -0.0365176
KYNU kynureninase -0.0365058
ENOSF1 enolase superfamily member 1 -0.0361525
NIPBL Nipped-B homolog (Drosophila) -0.0357693
BCAS1 breast carcinoma amplified sequence 1 -0.0355915
SFPQ splicing factor proline/glutamine-rich -0.0353792
EPHA4 EPH receptor A4 -0.0350495
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0347011
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0346783
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -0.034557
RNF216 ring finger protein 216 -0.0341547
KDM2A lysine (K)-specific demethylase 2A -0.0341454
TRAPPC9 trafficking protein particle complex 9 -0.0341027
EVL Enah/Vasp-like -0.033686
CBX5 chromobox homolog 5 -0.0335223
RNGTT RNA guanylyltransferase and 5'-phosphatase -0.0334525
PRKCA protein kinase C, alpha -0.032808
CD81 CD81 molecule -0.0326238
CHD6 chromodomain helicase DNA binding protein 6 -0.0325049
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.0324776
SCAPER S-phase cyclin A-associated protein in the ER -0.031407
AFF4 AF4/FMR2 family, member 4 -0.0312997
SPPL2A signal peptide peptidase like 2A -0.031043
HIPK2 homeodomain interacting protein kinase 2 -0.0310078
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.0307706
RACK1 receptor for activated C kinase 1 -0.0305115
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.0303125
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0301067
EEF2 eukaryotic translation elongation factor 2 -0.0300643
MED13 mediator complex subunit 13 -0.0299939
SKA2 spindle and kinetochore associated complex subunit 2 -0.0299177
GOLGA4 golgin A4 -0.029847
TUBB tubulin, beta class I -0.0297638
ASCC3 activating signal cointegrator 1 complex subunit 3 -0.0296147
TMEM178B transmembrane protein 178B -0.0295062
FOXK2 forkhead box K2 -0.0294995
LPP LIM domain containing preferred translocation partner in lipoma -0.0294586
ADCY9 adenylate cyclase 9 -0.0294579
SMC4 structural maintenance of chromosomes 4 -0.0293296
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -0.0292439
PFN1 profilin 1 -0.0289459
CEP350 centrosomal protein 350kDa -0.0284761
PSEN1 presenilin 1 -0.0284235
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0278635
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -0.0278464
AVL9 AVL9 homolog (S. cerevisiase) -0.0276008
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0272464
POTEF POTE ankyrin domain family, member F -0.0272451
ANKRD11 ankyrin repeat domain 11 -0.027183
CHLSN cholesin -0.0269723
CADPS2 Ca++-dependent secretion activator 2 -0.0269707
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.026942
OGA O-GlcNAcase -0.0269243
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0267282
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.0266048
SHANK2 SH3 and multiple ankyrin repeat domains 2 -0.0265954
MYO10 myosin X -0.0263437
TRIM27 tripartite motif containing 27 -0.0261964
MSH3 mutS homolog 3 -0.026125
BRCA1 breast cancer 1, early onset -0.0260794
SRRM1 serine/arginine repetitive matrix 1 -0.0260325
QSER1 glutamine and serine rich 1 -0.0260177
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0260041
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -0.025776
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein -0.0257377
EXT1 exostosin glycosyltransferase 1 -0.0256519
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -0.025577
MGMT O-6-methylguanine-DNA methyltransferase -0.0253363
ATXN2 ataxin 2 -0.0253273
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -0.0252034
UBB ubiquitin B -0.0251392
AKAP9 A kinase (PRKA) anchor protein 9 -0.025048
TOP1 topoisomerase (DNA) I -0.0250144
OSBPL10 oxysterol binding protein-like 10 -0.0249943
TXN2 thioredoxin 2 -0.0248503
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 -0.0247561
MRFAP1 Morf4 family associated protein 1 -0.024653
IQANK1 IQ motif and ankyrin repeat containing 1 -0.0244253
UBE2E2 ubiquitin-conjugating enzyme E2E 2 -0.024405
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0243979
DNPEP aspartyl aminopeptidase -0.0243711
NCKAP5 NCK-associated protein 5 -0.0243436
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -0.0242532
EEIG2 EEIG family member 2 -0.0242523
RPL36A ribosomal protein L36a -0.0239957
ILF3 interleukin enhancer binding factor 3, 90kDa -0.0239282
ZNRF3 zinc and ring finger 3 -0.0238838
SETX senataxin -0.0238745
CCT7 chaperonin containing TCP1, subunit 7 (eta) -0.0238337
FBXL18 F-box and leucine-rich repeat protein 18 -0.0237094
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.0235532
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -0.0235497
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -0.0233876
CENPE centromere protein E, 312kDa -0.0233711
SPPL3 signal peptide peptidase like 3 -0.0233053
SVIL supervillin -0.0232965
RSF1 remodeling and spacing factor 1 -0.0231927
FRS2 fibroblast growth factor receptor substrate 2 -0.0231566
ERC1 ELKS/RAB6-interacting/CAST family member 1 -0.023149
NPNT nephronectin -0.0231095
NPC2 Niemann-Pick disease, type C2 -0.023074
EPN2 epsin 2 -0.0229429
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -0.0229026
CENPP centromere protein P -0.0228548
PTPN14 protein tyrosine phosphatase, non-receptor type 14 -0.0228451
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0227888
PGR progesterone receptor -0.0227108
ZNF292 zinc finger protein 292 -0.0227087
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 -0.0227056
SRBD1 S1 RNA binding domain 1 -0.0226976
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -0.0226125
ATAD2 ATPase family, AAA domain containing 2 -0.0225701
PRPF3 pre-mRNA processing factor 3 -0.0225291
PCED1B PC-esterase domain containing 1B -0.0224568
RPL35 ribosomal protein L35 -0.0224433
S100A11 S100 calcium binding protein A11 -0.0223895
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0223892
ARL15 ADP-ribosylation factor-like 15 -0.0223501
THADA thyroid adenoma associated -0.0221903
KIF4A kinesin family member 4A -0.02205
REPS1 RALBP1 associated Eps domain containing 1 -0.0220298
FANCI Fanconi anemia, complementation group I -0.0220208
HOMER2 homer scaffolding protein 2 -0.0220116
FAF1 Fas (TNFRSF6) associated factor 1 -0.0219896
RPS14 ribosomal protein S14 -0.021982
TLK1 tousled-like kinase 1 -0.0219476
PUM1 pumilio RNA-binding family member 1 -0.0218818
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 -0.0218753
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB -0.0217675
ADAM17 ADAM metallopeptidase domain 17 -0.0217602
ACBD6 acyl-CoA binding domain containing 6 -0.0216647
RPL7 ribosomal protein L7 -0.0216529
TTLL10 tubulin tyrosine ligase-like family member 10 -0.0216207
EHBP1 EH domain binding protein 1 -0.0215624
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa -0.0215529
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -0.0215285
MAST2 microtubule associated serine/threonine kinase 2 -0.021457
ASCC2 activating signal cointegrator 1 complex subunit 2 -0.0214103
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.0213754
RPL7A ribosomal protein L7a -0.0213561
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -0.0212895
LONP2 lon peptidase 2, peroxisomal -0.0212806
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0211909
NBAS neuroblastoma amplified sequence -0.0211538
HDGFL3 HDGF like 3 -0.0211461
MTSS1 metastasis suppressor 1 -0.0211397
CMIP c-Maf inducing protein -0.0210296
TLN2 talin 2 -0.0209647
NCOR2 nuclear receptor corepressor 2 -0.0209353
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0208715
GPHRA golgi pH regulator A -0.0208628
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit -0.0206586
SMG6 SMG6 nonsense mediated mRNA decay factor -0.0206557
PTPN2 protein tyrosine phosphatase, non-receptor type 2 -0.0206371
COPE coatomer protein complex, subunit epsilon -0.0206312
DCAF7 DDB1 and CUL4 associated factor 7 -0.0205361
ODF2 outer dense fiber of sperm tails 2 -0.0205227
MYO5A myosin VA (heavy chain 12, myoxin) -0.0205172
GABPB1 GA binding protein transcription factor, beta subunit 1 -0.0205101
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0204136
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -0.0203803
SPTAN1 spectrin, alpha, non-erythrocytic 1 -0.0203
SRRM2 serine/arginine repetitive matrix 2 -0.0202935
PTMA prothymosin, alpha -0.0202255
MCM7 minichromosome maintenance complex component 7 -0.0202202
E2F3 E2F transcription factor 3 -0.0201933
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0200916
PCCA propionyl CoA carboxylase, alpha polypeptide -0.0200878
CSDE1 cold shock domain containing E1, RNA-binding -0.0200802
MPG N-methylpurine-DNA glycosylase -0.0200725
REST RE1-silencing transcription factor -0.0200565
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase -0.0200402
RUNX1 runt-related transcription factor 1 -0.0200298
HAX1 HCLS1 associated protein X-1 -0.0199992
CA12 carbonic anhydrase XII -0.0199489
ADRM1 adhesion regulating molecule 1 -0.0199443
TATDN1 TatD DNase domain containing 1 -0.0198679
PTK2 protein tyrosine kinase 2 -0.0198077
BLVRB biliverdin reductase B -0.0198045
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0197812
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -0.0197068
GNPDA1 glucosamine-6-phosphate deaminase 1 -0.0196632
BTBD7 BTB (POZ) domain containing 7 -0.0196621
BMPR1A bone morphogenetic protein receptor, type IA -0.0195554
TPR translocated promoter region, nuclear basket protein -0.0195349
FNBP4 formin binding protein 4 -0.0195321
PPP1R21 protein phosphatase 1, regulatory subunit 21 -0.0195066
NCOA3 nuclear receptor coactivator 3 -0.0194501
HEATR6 HEAT repeat containing 6 -0.0194307
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.0193934
CHURC1 churchill domain containing 1 -0.0193299
APOLD1 apolipoprotein L domain containing 1 -0.0192353
AKAP13 A kinase (PRKA) anchor protein 13 -0.0192348
MIPEP mitochondrial intermediate peptidase -0.0192004
NR2C2 nuclear receptor subfamily 2, group C, member 2 -0.0191922
TRIQK triple QxxK/R motif containing -0.0190337
RPL35A ribosomal protein L35a -0.0190168
CNOT6 CCR4-NOT transcription complex, subunit 6 -0.0189499
EDF1 endothelial differentiation-related factor 1 -0.0189376
UBE2Z ubiquitin-conjugating enzyme E2Z -0.0189193
PRC1 protein regulator of cytokinesis 1 -0.0188507
RPSA ribosomal protein SA -0.0188504
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -0.0188479
KIF20B kinesin family member 20B -0.0188337
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -0.0188324
TSEN2 TSEN2 tRNA splicing endonuclease subunit -0.018822
NALF1 NALCN channel auxiliary factor 1 -0.0188103
CCDC170 coiled-coil domain containing 170 -0.0188087
RC3H2 ring finger and CCCH-type domains 2 -0.0187115
RBM15 RNA binding motif protein 15 -0.0187003
SSBP2 single-stranded DNA binding protein 2 -0.0186545
UNK unkempt family zinc finger -0.0185346
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase -0.0185284
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0185261
KDM3B lysine (K)-specific demethylase 3B -0.0184301
NR6A1 nuclear receptor subfamily 6, group A, member 1 -0.0183201
UBE2M ubiquitin-conjugating enzyme E2M -0.0182992
DCTN5 dynactin 5 (p25) -0.0182988
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 -0.0182879
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -0.0181753
PPP1R9A protein phosphatase 1, regulatory subunit 9A -0.0181735
MCM4 minichromosome maintenance complex component 4 -0.0181126
PARD3 par-3 family cell polarity regulator -0.0181076
NACA nascent polypeptide-associated complex alpha subunit -0.0180762
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa -0.0180617
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0180589
KIAA0586 KIAA0586 -0.0180142
MAP3K20 mitogen-activated protein kinase kinase kinase 20 -0.0180083
STK39 serine threonine kinase 39 -0.0179575
MUSK muscle, skeletal, receptor tyrosine kinase -0.0178021
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 -0.0177805
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B -0.0177657
HIBADH 3-hydroxyisobutyrate dehydrogenase -0.0177101
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -0.0176947
EP400 E1A binding protein p400 -0.0176784
ENO1 enolase 1, (alpha) -0.0176462
NUP210 nucleoporin 210kDa -0.0176404
U2SURP U2 snRNP-associated SURP domain containing -0.0176385
MGA MGA, MAX dimerization protein -0.0176264
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 -0.0176058
FOXA1 forkhead box A1 -0.0175884
XPO1 exportin 1 -0.0175465
KMT2C lysine (K)-specific methyltransferase 2C -0.0174625
PRPF8 pre-mRNA processing factor 8 -0.0174302
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -0.0174121
RPLP2 ribosomal protein, large, P2 -0.0173896
SON SON DNA binding protein -0.0173161
AGO3 argonaute RISC catalytic component 3 -0.0173028
PCNA proliferating cell nuclear antigen -0.0172848
SUSD4 sushi domain containing 4 -0.0172478
CDK13 cyclin-dependent kinase 13 -0.0171452
TRA2B transformer 2 beta homolog (Drosophila) -0.0171196
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.0170613
RAD18 RAD18 E3 ubiquitin protein ligase -0.0170527
PALS1 protein associated with LIN7 1, MAGUK p55 family member -0.0170237
RPS19 ribosomal protein S19 -0.0169859
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 -0.0169688
LOC112694756 uncharaterized LOC112694756 -0.0169658
ARHGAP11B Rho GTPase activating protein 11B -0.0169462
TMPO thymopoietin -0.0168709
MKI67 marker of proliferation Ki-67 -0.0168612
XPO6 exportin 6 -0.016827
INTS2 integrator complex subunit 2 -0.0168259
RPS4X ribosomal protein S4, X-linked -0.0168241
KNOP1 lysine-rich nucleolar protein 1 -0.016802
THRAP3 thyroid hormone receptor associated protein 3 -0.0167776
AHI1 Abelson helper integration site 1 -0.0167514
FOXK1 forkhead box K1 -0.0167388
MYO1B myosin IB -0.0167375
MTDH metadherin -0.0166966
ANKIB1 ankyrin repeat and IBR domain containing 1 -0.016688
TMEM120B transmembrane protein 120B -0.0166843
PNISR PNN-interacting serine/arginine-rich protein -0.0166619
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) -0.0166313
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0165887
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -0.016584
IFI27 interferon, alpha-inducible protein 27 -0.0165592
EP300 E1A binding protein p300 -0.0165503
TNPO1 transportin 1 -0.0165373
WSB1 WD repeat and SOCS box containing 1 -0.0165005
MCMBP minichromosome maintenance complex binding protein -0.0164885
NME1 NME/NM23 nucleoside diphosphate kinase 1 -0.0164764
C21ORF58 chromosome 21 open reading frame 58 -0.0164666
HDGF hepatoma-derived growth factor -0.0164212
MCU mitochondrial calcium uniporter -0.0163945
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) -0.0163874
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.0163591
PCNT pericentrin -0.0163553
FNDC3B fibronectin type III domain containing 3B -0.0163506
LY6E lymphocyte antigen 6 complex, locus E -0.0163402
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa -0.0162949
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains -0.016294
PPP1R10 protein phosphatase 1, regulatory subunit 10 -0.016257
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -0.0162548
PDZRN3 PDZ domain containing ring finger 3 -0.0162491
DPP8 dipeptidyl-peptidase 8 -0.0162366
KDM2B lysine (K)-specific demethylase 2B -0.0161791
DGKH diacylglycerol kinase, eta -0.0161539
LSG1 large 60S subunit nuclear export GTPase 1 -0.0161431
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 -0.0161099
USP47 ubiquitin specific peptidase 47 -0.0160993
ARID1B AT rich interactive domain 1B (SWI1-like) -0.0160817
KMT5B lysine methyltransferase 5B -0.0160669
RPL31 ribosomal protein L31 -0.0160305
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0160133
SZRD1 SUZ RNA binding domain containing 1 -0.015962
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 -0.0159323
FUBP1 far upstream element (FUSE) binding protein 1 -0.0159183
PHC3 polyhomeotic homolog 3 (Drosophila) -0.0158573
PRKD1 protein kinase D1 -0.0158365
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -0.0158134
BMPR1B bone morphogenetic protein receptor, type IB -0.0157977
TTC3 tetratricopeptide repeat domain 3 -0.0157703
SAPCD2 suppressor APC domain containing 2 -0.015743
MOCOS molybdenum cofactor sulfurase -0.0157358
VRK3 vaccinia related kinase 3 -0.0157334
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -0.0157042
PCDH9 protocadherin 9 -0.015681
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0156588
ATP5MJ ATP synthase membrane subunit j -0.0156349
GEMIN5 gem (nuclear organelle) associated protein 5 -0.0156048
GREB1 growth regulation by estrogen in breast cancer 1 -0.0156035
ATP5F1B ATP synthase F1 subunit beta -0.0155908
DMXL2 Dmx-like 2 -0.015499
EVI5 ecotropic viral integration site 5 -0.0154625
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -0.015451
TMEM51 transmembrane protein 51 -0.0154434
ARHGAP26 Rho GTPase activating protein 26 -0.0154289
ARHGAP35 Rho GTPase activating protein 35 -0.0154234
AGO2 argonaute RISC catalytic component 2 -0.0154197
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -0.0153881
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.0153762
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase -0.0153747
PEBP1 phosphatidylethanolamine binding protein 1 -0.0153724
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -0.0153208
HNRNPF heterogeneous nuclear ribonucleoprotein F -0.015315
ATG7 autophagy related 7 -0.015302
AMZ1 archaelysin family metallopeptidase 1 -0.0152855
ZBTB7A zinc finger and BTB domain containing 7A -0.0152803
WWC1 WW and C2 domain containing 1 -0.0152705
MAPK14 mitogen-activated protein kinase 14 -0.0152326
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -0.015226
AP3D1 adaptor-related protein complex 3, delta 1 subunit -0.0152053
COPZ1 coatomer protein complex, subunit zeta 1 -0.0151967
SEC11A SEC11 homolog A (S. cerevisiae) -0.015189
R3HDM1 R3H domain containing 1 -0.0151645
MRTFA myocardin related transcription factor A -0.0151505
RNASE3 ribonuclease, RNase A family, 3 -0.0151466
SEPHS2 selenophosphate synthetase 2 -0.0151212
TCERG1 transcription elongation regulator 1 -0.0151072
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -0.0150976
ZSWIM5 zinc finger, SWIM-type containing 5 -0.0150838
MYO6 myosin VI -0.0150783
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -0.0150555
MROH1 maestro heat-like repeat family member 1 -0.0150554
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa -0.0150341
PRICKLE2 prickle homolog 2 (Drosophila) -0.0150003
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 -0.0149864
DPEP2 dipeptidase 2 -0.0149861
ADAR adenosine deaminase, RNA-specific -0.0149585
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -0.014934
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -0.0149089
PDPR pyruvate dehydrogenase phosphatase regulatory subunit -0.0149087
PRDM2 PR domain containing 2, with ZNF domain -0.0149038
CEP192 centrosomal protein 192kDa -0.0148926
LAPTM4A lysosomal protein transmembrane 4 alpha -0.0148809
SHISA9 shisa family member 9 -0.0148375
FAM168B family with sequence similarity 168, member B -0.0148129
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0147945
BAZ1B bromodomain adjacent to zinc finger domain, 1B -0.0147881
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -0.0147617
LIMD1 LIM domains containing 1 -0.0147389
ABHD3 abhydrolase domain containing 3 -0.014736
PRIM2 primase, DNA, polypeptide 2 (58kDa) -0.0147354
MARVELD2 MARVEL domain containing 2 -0.0147291
LAMA5 laminin, alpha 5 -0.0147286
RAD21 RAD21 homolog (S. pombe) -0.0147132
STK10 serine/threonine kinase 10 -0.01471
RAB7A RAB7A, member RAS oncogene family -0.0146974
CUEDC1 CUE domain containing 1 -0.0146624
ZNF385B zinc finger protein 385B -0.014645
RAB1A RAB1A, member RAS oncogene family -0.0146086
KIF2A kinesin heavy chain member 2A -0.0146019
IPO9 importin 9 -0.0145969
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.014592
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.0145629
GATAD2B GATA zinc finger domain containing 2B -0.0145476
APRT adenine phosphoribosyltransferase -0.014513
WAPL WAPL cohesin release factor -0.0144869
INTS6 integrator complex subunit 6 -0.0144838
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) -0.0144836
ABLIM1 actin binding LIM protein 1 -0.0144817
DSTYK dual serine/threonine and tyrosine protein kinase -0.0144786
GAS2L3 growth arrest-specific 2 like 3 -0.0144784
FBXO11 F-box protein 11 -0.0144728
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) -0.0144678
PARK7 parkinson protein 7 -0.0144651
SMYD3 SET and MYND domain containing 3 -0.0144571
TMEM184C transmembrane protein 184C -0.0144282
RAB6A RAB6A, member RAS oncogene family -0.0144079
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0143982
GPD1L glycerol-3-phosphate dehydrogenase 1-like -0.0143849
ZNF91 zinc finger protein 91 -0.0143828
RREB1 ras responsive element binding protein 1 -0.0143682
RAB11FIP3 RAB11 family interacting protein 3 (class II) -0.0143329
TRAM2 translocation associated membrane protein 2 -0.0143274
NCAPD2 non-SMC condensin I complex, subunit D2 -0.0142289
PTGES3 prostaglandin E synthase 3 (cytosolic) -0.0142252
FOXN3 forkhead box N3 -0.014216
IPO4 importin 4 -0.0142075
NOVA1 neuro-oncological ventral antigen 1 -0.014203
NSD3 nuclear receptor binding SET domain protein 3 -0.0142027
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.0141966
ATF4 activating transcription factor 4 -0.0141749
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) -0.0141626
ZCCHC10 zinc finger, CCHC domain containing 10 -0.0141332
EXOSC1 exosome component 1 -0.0141205
BLTP3A bridge-like lipid transfer protein family member 3A -0.0141041
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 -0.014058
ABI2 abl-interactor 2 -0.014056
ACACA acetyl-CoA carboxylase alpha -0.0140457
SNX6 sorting nexin 6 -0.0140418
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein -0.0140099
PI4KB phosphatidylinositol 4-kinase, catalytic, beta -0.0140002
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) -0.0139797
SCMH1 sex comb on midleg homolog 1 (Drosophila) -0.0139659
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 -0.0139206
PFKL phosphofructokinase, liver -0.0139182
AATF apoptosis antagonizing transcription factor -0.0139176
CBX3 chromobox homolog 3 -0.0139157
ZFR zinc finger RNA binding protein -0.0139149
ESRP1 epithelial splicing regulatory protein 1 -0.0139044
PELP1 proline, glutamate and leucine rich protein 1 -0.0138953
BRCA2 breast cancer 2, early onset -0.0138904
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -0.0138607
RCOR1 REST corepressor 1 -0.0138252
TMOD3 tropomodulin 3 (ubiquitous) -0.0138184
KANSL2 KAT8 regulatory NSL complex subunit 2 -0.0138052
GPR160 G protein-coupled receptor 160 -0.0138043
ADCY8 adenylate cyclase 8 (brain) -0.0137876
DUT deoxyuridine triphosphatase -0.0137599
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -0.0137327
TM9SF3 transmembrane 9 superfamily member 3 -0.0137249
GCFC2 GC-rich sequence DNA-binding factor 2 -0.0137045
RBPMS RNA binding protein with multiple splicing -0.0137039
DGCR8 DGCR8 microprocessor complex subunit -0.0137018
NUP153 nucleoporin 153kDa -0.0136828
ANKMY1 ankyrin repeat and MYND domain containing 1 -0.0136456
CEP83 centrosomal protein 83kDa -0.0136399
WDR27 WD repeat domain 27 -0.0136319
FRMD4A FERM domain containing 4A -0.0136174
TBK1 TANK-binding kinase 1 -0.0136086
NANS N-acetylneuraminic acid synthase -0.0136059
PCNX4 pecanex 4 -0.013583
LONRF2 LON peptidase N-terminal domain and ring finger 2 -0.0135466
MBTPS1 membrane-bound transcription factor peptidase, site 1 -0.0135296
RHBDD1 rhomboid domain containing 1 -0.0134803
H1-10 H1.10 linker histone -0.0134513
YEATS2 YEATS domain containing 2 -0.0134217
TASOR2 transcription activation suppressor family member 2 -0.0134138