MCF7_GSK-LSD1 2HCl_1µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description GSK-LSD1 2HCl 1µM perturbation in MCF7 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the MCF7_GSK-LSD1 2HCl_1µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
TTC28 tetratricopeptide repeat domain 28 0.180955
OVOL2 ovo-like zinc finger 2 0.175789
NCOA3 nuclear receptor coactivator 3 0.158249
THSD4 thrombospondin, type I, domain containing 4 0.112711
CTSD cathepsin D 0.0969541
BCAS3 breast carcinoma amplified sequence 3 0.082423
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.0778021
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.0733866
ZMYND8 zinc finger, MYND-type containing 8 0.0718434
TFF1 trefoil factor 1 0.0679518
MYOF myoferlin 0.0672972
PKM pyruvate kinase, muscle 0.0659447
MSI2 musashi RNA-binding protein 2 0.0652545
RAD51C RAD51 paralog C 0.0647849
NRIP1 nuclear receptor interacting protein 1 0.064768
ZRANB3 zinc finger, RAN-binding domain containing 3 0.0633873
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 0.0627927
PTPRG protein tyrosine phosphatase, receptor type, G 0.0625946
MALRD1 MAM and LDL receptor class A domain containing 1 0.0616899
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0590399
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 0.0571364
CSDE1 cold shock domain containing E1, RNA-binding 0.0562452
RPL15 ribosomal protein L15 0.0550815
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.0531746
VMP1 vacuole membrane protein 1 0.0529639
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0504624
RACK1 receptor for activated C kinase 1 0.0496667
BCAS4 breast carcinoma amplified sequence 4 0.0482944
UBE2H ubiquitin-conjugating enzyme E2H 0.0466576
RABGAP1L RAB GTPase activating protein 1-like 0.0450396
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.0445547
HIP1 huntingtin interacting protein 1 0.044553
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.0439943
MED13 mediator complex subunit 13 0.0431098
SGMS1 sphingomyelin synthase 1 0.0424495
DIAPH2 diaphanous-related formin 2 0.042393
EXOC4 exocyst complex component 4 0.0420426
R3HDM1 R3H domain containing 1 0.042
NBEA neurobeachin 0.0414112
PHACTR4 phosphatase and actin regulator 4 0.0405075
GREB1 growth regulation by estrogen in breast cancer 1 0.0404668
AOPEP aminopeptidase O (putative) 0.0403847
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 0.0403784
ZNF217 zinc finger protein 217 0.0399256
MPHOSPH9 M-phase phosphoprotein 9 0.0398772
POGZ pogo transposable element with ZNF domain 0.0397625
COL5A1 collagen, type V, alpha 1 0.0391065
CPA6 carboxypeptidase A6 0.0390804
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0390403
LDLR low density lipoprotein receptor 0.0387742
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0386988
RPL32 ribosomal protein L32 0.0378038
ITGB5 integrin, beta 5 0.0374117
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.037407
ENO1 enolase 1, (alpha) 0.0374048
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 0.0371897
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0369425
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0368964
FLNA filamin A, alpha 0.0366485
RNF115 ring finger protein 115 0.0365299
MUC1 mucin 1, cell surface associated 0.0364761
TUBB tubulin, beta class I 0.0362455
RPS2 ribosomal protein S2 0.0360987
RHPN2 rhophilin, Rho GTPase binding protein 2 0.0358856
RPL37 ribosomal protein L37 0.0358093
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 0.0358026
DCDC2 doublecortin domain containing 2 0.0348561
STC2 stanniocalcin 2 0.0342699
ZBTB20 zinc finger and BTB domain containing 20 0.0342113
DGKH diacylglycerol kinase, eta 0.0341946
LRMDA leucine rich melanocyte differentiation associated 0.0335586
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.0332311
GOLGB1 golgin B1 0.0332162
SLC38A1 solute carrier family 38, member 1 0.033212
ELP2 elongator acetyltransferase complex subunit 2 0.0331265
SRPK2 SRSF protein kinase 2 0.0329744
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.0329704
PTPRE protein tyrosine phosphatase, receptor type, E 0.0329698
PFN1 profilin 1 0.0327264
UIMC1 ubiquitin interaction motif containing 1 0.0325487
RPS5 ribosomal protein S5 0.0322099
XBP1 X-box binding protein 1 0.0321659
MAML3 mastermind-like 3 (Drosophila) 0.0320177
TOB1 transducer of ERBB2, 1 0.0318694
DENND4A DENN/MADD domain containing 4A 0.0314184
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 0.0311566
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.0308643
NEO1 neogenin 1 0.0305849
EEF2 eukaryotic translation elongation factor 2 0.0305657
FAM174B family with sequence similarity 174, member B 0.0302157
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0301163
CHD4 chromodomain helicase DNA binding protein 4 0.0301143
TENM3 teneurin transmembrane protein 3 0.0300522
GRAMD1A GRAM domain containing 1A 0.0298929
PARD3B par-3 family cell polarity regulator beta 0.0296827
RPLP1 ribosomal protein, large, P1 0.0294361
GPC6 glypican 6 0.0293713
RNFT2 ring finger protein, transmembrane 2 0.0293137
CERS4 ceramide synthase 4 0.0293021
PHF14 PHD finger protein 14 0.0292387
AUTS2 autism susceptibility candidate 2 0.0291233
ARSG arylsulfatase G 0.0290012
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.0289186
DCAF7 DDB1 and CUL4 associated factor 7 0.0288695
NRG3 neuregulin 3 0.0287999
HSPB1 heat shock 27kDa protein 1 0.0286703
SMYD3 SET and MYND domain containing 3 0.0286548
FANCC Fanconi anemia, complementation group C 0.0285042
CTNND2 catenin (cadherin-associated protein), delta 2 0.0281226
WWOX WW domain containing oxidoreductase 0.0280121
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0279994
TEX14 testis expressed 14 0.0277721
DSTN destrin (actin depolymerizing factor) 0.0276072
USP32 ubiquitin specific peptidase 32 0.027589
TMEM165 transmembrane protein 165 0.0272372
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.0270904
HOMER2 homer scaffolding protein 2 0.0268354
AMZ1 archaelysin family metallopeptidase 1 0.0266367
AHNAK2 AHNAK nucleoprotein 2 0.0266121
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0264166
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 0.0262943
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.0261759
MAST4 microtubule associated serine/threonine kinase family member 4 0.0258365
ECE1 endothelin converting enzyme 1 0.0257822
MECP2 methyl CpG binding protein 2 0.0255391
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 0.0255176
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0254739
ZEB1 zinc finger E-box binding homeobox 1 0.0254268
WWTR1 WW domain containing transcription regulator 1 0.0254042
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.0253776
ATP11B ATPase, class VI, type 11B 0.0253498
PPP1R13B protein phosphatase 1, regulatory subunit 13B 0.0252038
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.0251495
USP8 ubiquitin specific peptidase 8 0.0251117
PDPR pyruvate dehydrogenase phosphatase regulatory subunit 0.024893
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.0248542
OTUD7B OTU deubiquitinase 7B 0.024837
PCSK6 proprotein convertase subtilisin/kexin type 6 0.0248309
PXDN peroxidasin 0.0248034
PCNX4 pecanex 4 0.0247632
ZFP64 ZFP64 zinc finger protein 0.024734
DENND5B DENN/MADD domain containing 5B 0.0245989
LGALS3 lectin, galactoside-binding, soluble, 3 0.0245073
TTL tubulin tyrosine ligase 0.0244191
DNPEP aspartyl aminopeptidase 0.0243995
CDPF1 cysteine-rich, DPF motif domain containing 1 0.024358
RPL37A ribosomal protein L37a 0.0241892
TANGO6 transport and golgi organization 6 homolog (Drosophila) 0.0241743
ANXA6 annexin A6 0.0241698
CLASP2 cytoplasmic linker associated protein 2 0.0240806
RPS17 ribosomal protein S17 0.0240581
RPS16 ribosomal protein S16 0.0240249
POLK polymerase (DNA directed) kappa 0.0239975
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.02398
ATM ATM serine/threonine kinase 0.0238982
SMIM14 small integral membrane protein 14 0.0238821
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 0.0236986
JAK2 Janus kinase 2 0.0233956
CCDC170 coiled-coil domain containing 170 0.0232762
SACS sacsin molecular chaperone 0.0232722
AKAP13 A kinase (PRKA) anchor protein 13 0.0231243
CDV3 CDV3 homolog (mouse) 0.0228677
BSG basigin (Ok blood group) 0.0228245
PCM1 pericentriolar material 1 0.0227603
ELOVL5 ELOVL fatty acid elongase 5 0.0227048
PTK2 protein tyrosine kinase 2 0.0226673
RPL7 ribosomal protein L7 0.0226513
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.022591
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.0225307
TSC22D1 TSC22 domain family, member 1 0.0225202
HSH2D hematopoietic SH2 domain containing 0.0225169
RPS3 ribosomal protein S3 0.0224626
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 0.0223954
TASP1 taspase, threonine aspartase, 1 0.0223627
ATRAID all-trans retinoic acid-induced differentiation factor 0.0222428
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 0.0222005
MDK midkine (neurite growth-promoting factor 2) 0.0221729
EIF4B eukaryotic translation initiation factor 4B 0.0219936
CMC2 C-x(9)-C motif containing 2 0.0218735
MEF2A myocyte enhancer factor 2A 0.021664
CELF1 CUGBP, Elav-like family member 1 0.0215683
RBL2 retinoblastoma-like 2 0.0215576
RPL7L1 ribosomal protein L7-like 1 0.021483
ITGB4 integrin, beta 4 0.021458
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) 0.0214319
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 0.0214169
CDC27 cell division cycle 27 0.0213723
RPS15 ribosomal protein S15 0.0213698
PTPRF protein tyrosine phosphatase, receptor type, F 0.0213657
STARD10 StAR-related lipid transfer (START) domain containing 10 0.0213654
WDFY3 WD repeat and FYVE domain containing 3 0.0213299
FBXL17 F-box and leucine-rich repeat protein 17 0.0212995
PRKCSH protein kinase C substrate 80K-H 0.0211841
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 0.0211438
RPL7A ribosomal protein L7a 0.0211426
PCNX1 pecanex 1 0.0211026
ADI1 acireductone dioxygenase 1 0.0210737
NCOA4 nuclear receptor coactivator 4 0.0210533
GTF2I general transcription factor IIi 0.02102
CEP112 centrosomal protein 112kDa 0.0209968
FAM193A family with sequence similarity 193, member A 0.020976
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0209175
EPHA6 EPH receptor A6 0.0209168
ARL15 ADP-ribosylation factor-like 15 0.0208935
STOM stomatin 0.0208856
PDIA3 protein disulfide isomerase family A, member 3 0.0208207
IGFBP4 insulin-like growth factor binding protein 4 0.0207573
GNAS GNAS complex locus 0.0207254
PFKL phosphofructokinase, liver 0.0207186
GLI3 GLI family zinc finger 3 0.0206986
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0206411
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.0206103
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 0.0205821
PGM2L1 phosphoglucomutase 2-like 1 0.0203762
CEP170 centrosomal protein 170kDa 0.0203502
ZNF346 zinc finger protein 346 0.0203474
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0203365
ATP5F1E ATP synthase F1 subunit epsilon 0.0202886
G2E3 G2/M-phase specific E3 ubiquitin protein ligase 0.0202439
ACTN1 actinin, alpha 1 0.0201957
TRIM37 tripartite motif containing 37 0.0201927
TCF12 transcription factor 12 0.0201427
FAM13B family with sequence similarity 13, member B 0.0201035
SCAF11 SR-related CTD-associated factor 11 0.0200998
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 0.0200638
NOL10 nucleolar protein 10 0.0198636
ANXA2 annexin A2 0.0198603
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0197378
TMX4 thioredoxin-related transmembrane protein 4 0.0197268
KIF1B kinesin family member 1B 0.0195708
ZNF148 zinc finger protein 148 0.0195407
RPS21 ribosomal protein S21 0.0195397
INVS inversin 0.0194802
ZNF644 zinc finger protein 644 0.0194793
CMSS1 cms1 ribosomal small subunit homolog (yeast) 0.0194354
DDHD1 DDHD domain containing 1 0.0194304
APMAP adipocyte plasma membrane associated protein 0.0193842
SLC44A1 solute carrier family 44 (choline transporter), member 1 0.0193515
HRNR hornerin 0.0193067
NAP1L1 nucleosome assembly protein 1-like 1 0.0193036
TLE5 TLE family member 5, transcriptional modulator 0.0191691
NXNL2 nucleoredoxin-like 2 0.0191547
NINL ninein-like 0.0190753
CUTA cutA divalent cation tolerance homolog (E. coli) 0.0190505
DNMBP dynamin binding protein 0.0190397
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 0.0190338
USP42 ubiquitin specific peptidase 42 0.0189072
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 0.0189033
SSH1 slingshot protein phosphatase 1 0.0188463
SPPL2A signal peptide peptidase like 2A 0.0188057
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.018776
EYA2 EYA transcriptional coactivator and phosphatase 2 0.0187689
PGR progesterone receptor 0.0187568
TMEM44 transmembrane protein 44 0.0187409
ACBD6 acyl-CoA binding domain containing 6 0.0187245
USP36 ubiquitin specific peptidase 36 0.0187185
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.0186548
FAM20B family with sequence similarity 20, member B 0.0186406
ZNF33A zinc finger protein 33A 0.018628
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) 0.0185755
LMAN2 lectin, mannose-binding 2 0.0184928
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta 0.0184775
CALR calreticulin 0.0183981
REST RE1-silencing transcription factor 0.0183793
ESYT1 extended synaptotagmin-like protein 1 0.0183781
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.0182752
TRAM2 translocation associated membrane protein 2 0.018209
FRS2 fibroblast growth factor receptor substrate 2 0.0181643
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 0.0181337
LCOR ligand dependent nuclear receptor corepressor 0.0180914
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 0.018077
PRR11 proline rich 11 0.0180482
DNM1L dynamin 1-like 0.0180343
SPNS1 spinster homolog 1 (Drosophila) 0.0180022
ADARB1 adenosine deaminase, RNA-specific, B1 0.0179897
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.0179827
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.0179777
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0179736
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.017969
MLEC malectin 0.0179626
TTBK2 tau tubulin kinase 2 0.0179548
CDK19 cyclin-dependent kinase 19 0.0179207
NT5C3A 5'-nucleotidase, cytosolic IIIA 0.0178681
PPDPF pancreatic progenitor cell differentiation and proliferation factor 0.0178646
DCAF11 DDB1 and CUL4 associated factor 11 0.0178129
TNPO1 transportin 1 0.0178065
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 0.0178042
DPP7 dipeptidyl-peptidase 7 0.0177205
RPS19 ribosomal protein S19 0.0176453
MUSK muscle, skeletal, receptor tyrosine kinase 0.0176287
DAND5 DAN domain family member 5, BMP antagonist 0.0176278
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0175943
ACSS3 acyl-CoA synthetase short-chain family member 3 0.0175865
BTBD9 BTB (POZ) domain containing 9 0.017584
CMIP c-Maf inducing protein 0.0175537
MRTFB myocardin related transcription factor B 0.0174986
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 0.0174623
KIAA0319L KIAA0319-like 0.0174347
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0173756
CHD6 chromodomain helicase DNA binding protein 6 0.0173702
XRRA1 X-ray radiation resistance associated 1 0.0173305
FAM168B family with sequence similarity 168, member B 0.0173016
RPL19 ribosomal protein L19 0.017296
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.0172941
KTN1 kinectin 1 (kinesin receptor) 0.0172898
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 0.0172016
TMEM120B transmembrane protein 120B 0.0171806
DPH6 diphthamine biosynthesis 6 0.017173
PARP4 poly (ADP-ribose) polymerase family, member 4 0.0171661
RSL1D1 ribosomal L1 domain containing 1 0.0171197
ZDHHC17 zinc finger, DHHC-type containing 17 0.017055
RGS12 regulator of G-protein signaling 12 0.0169821
KDM5B lysine (K)-specific demethylase 5B 0.0169727
FAM120A family with sequence similarity 120A 0.0169596
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 0.0169212
AIG1 androgen-induced 1 0.0169006
HLTF helicase-like transcription factor 0.0168958
LITAF lipopolysaccharide-induced TNF factor 0.0168955
CLSTN2 calsyntenin 2 0.0168941
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 0.0168894
PKN2 protein kinase N2 0.0168821
TFF3 trefoil factor 3 (intestinal) 0.0168626
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.0168196
FYB2 FYN binding protein 2 0.0167835
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 0.0167484
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 0.0167382
EPS8 epidermal growth factor receptor pathway substrate 8 0.0166981
ZSWIM5 zinc finger, SWIM-type containing 5 0.0166425
ANAPC11 anaphase promoting complex subunit 11 0.0166382
ZNF280D zinc finger protein 280D 0.0166091
MTSS1 metastasis suppressor 1 0.0165721
FXR1 fragile X mental retardation, autosomal homolog 1 0.0165598
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 0.0165591
CD58 CD58 molecule 0.0165182
PLEC plectin 0.0165094
KDM4B lysine (K)-specific demethylase 4B 0.0164774
RAB10 RAB10, member RAS oncogene family 0.016421
ADNP activity-dependent neuroprotector homeobox 0.0164144
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 0.0164128
CASZ1 castor zinc finger 1 0.0163814
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 0.0163302
COX6C cytochrome c oxidase subunit VIc 0.0163019
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit 0.0162857
PPP1R9A protein phosphatase 1, regulatory subunit 9A 0.0162855
PDS5A PDS5 cohesin associated factor A 0.0162243
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.0162062
SAP30BP SAP30 binding protein 0.0162046
RAD23B RAD23 homolog B (S. cerevisiae) 0.0161935
TUBA1C tubulin, alpha 1c 0.0161921
UTRN utrophin 0.0161782
GPRC5C G protein-coupled receptor, class C, group 5, member C 0.0161779
DHCR24 24-dehydrocholesterol reductase 0.0161422
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.0160179
PTPRK protein tyrosine phosphatase, receptor type, K 0.0160106
LPCAT3 lysophosphatidylcholine acyltransferase 3 0.0159979
MT2A metallothionein 2A 0.015974
CHD1 chromodomain helicase DNA binding protein 1 0.0159739
PODXL podocalyxin-like 0.015951
PRKCH protein kinase C, eta 0.0159347
XKR6 XK, Kell blood group complex subunit-related family, member 6 0.0159347
SHROOM2 shroom family member 2 0.0158844
LURAP1L leucine rich adaptor protein 1-like 0.0158784
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 0.015828
PDIA6 protein disulfide isomerase family A, member 6 0.0158034
FTH1 ferritin, heavy polypeptide 1 0.0157544
OSBPL10 oxysterol binding protein-like 10 0.0157535
TMEM131 transmembrane protein 131 0.0157288
NPNT nephronectin 0.0157209
GRID1 glutamate receptor, ionotropic, delta 1 0.0156995
UTP14C UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) 0.0156947
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0156916
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.0156888
GSE1 Gse1 coiled-coil protein 0.0156661
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.0156542
GNB5 guanine nucleotide binding protein (G protein), beta 5 0.015653
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 0.015647
PRAG1 PEAK1 related, kinase-activating pseudokinase 1 0.0156315
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.0156232
DIDO1 death inducer-obliterator 1 0.0156218
NGLY1 N-glycanase 1 0.0156095
COL18A1 collagen, type XVIII, alpha 1 0.0155988
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.0155911
TUFT1 tuftelin 1 0.0155491
KYAT1 kynurenine aminotransferase 1 0.0155203
CCNY cyclin Y 0.0155166
GLG1 golgi glycoprotein 1 0.0155056
SNED1 sushi, nidogen and EGF-like domains 1 0.0154952
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.0154703
RHOD ras homolog family member D 0.0154011
IKBIP IKBKB interacting protein 0.0153268
ABHD2 abhydrolase domain containing 2 0.0153104
PIBF1 progesterone immunomodulatory binding factor 1 0.0152823
VEZF1 vascular endothelial zinc finger 1 0.0152785
PTGFRN prostaglandin F2 receptor inhibitor 0.0152731
RHOU ras homolog family member U 0.0152494
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit 0.0152439
ZCCHC7 zinc finger, CCHC domain containing 7 0.0152006
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.0151784
WASHC5 WASH complex subunit 5 0.0151185
EMSY EMSY transcriptional repressor, BRCA2 interacting 0.0151054
TBK1 TANK-binding kinase 1 0.0151032
LAGE3 L antigen family, member 3 0.0150889
FBXW8 F-box and WD repeat domain containing 8 0.0150805
FOXN2 forkhead box N2 0.0149987
MXD4 MAX dimerization protein 4 0.0149856
GPATCH2L G patch domain containing 2-like 0.0149659
ZNF609 zinc finger protein 609 0.0149368
GKAP1 G kinase anchoring protein 1 0.014922
CERT1 ceramide transporter 1 0.0148405
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 0.0148171
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 0.0148165
DSG2 desmoglein 2 0.0148053
IVD isovaleryl-CoA dehydrogenase 0.014804
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.0148033
LARP1 La ribonucleoprotein domain family, member 1 0.0147997
STIM2 stromal interaction molecule 2 0.0147931
TULP4 tubby like protein 4 0.0147798
OSBPL9 oxysterol binding protein-like 9 0.0147711
CAMSAP1 calmodulin regulated spectrin-associated protein 1 0.0147577
PLIN3 perilipin 3 0.0147573
RHOC ras homolog family member C 0.0147297
FAM222B family with sequence similarity 222, member B 0.0146823
FRK fyn-related Src family tyrosine kinase 0.0146573
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa 0.0146558
SLMAP sarcolemma associated protein 0.0146474
RPL13A ribosomal protein L13a 0.0145818
ZNF618 zinc finger protein 618 0.0145772
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.0145734
XPR1 xenotropic and polytropic retrovirus receptor 1 0.0145669
CCDC91 coiled-coil domain containing 91 0.0145165
SDF4 stromal cell derived factor 4 0.0145163
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 0.0144941
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 0.0144816
TMEM135 transmembrane protein 135 0.0144722
MTRFR mitochondrial translation release factor in rescue 0.0144663
N4BP3 NEDD4 binding protein 3 0.0144349
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12 0.01439
UBL4A ubiquitin-like 4A 0.0143882
TACC1 transforming, acidic coiled-coil containing protein 1 0.0143861
CD59 CD59 molecule, complement regulatory protein 0.0143826
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 0.0143789
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase 0.0143453
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.0143205
UGDH UDP-glucose 6-dehydrogenase 0.014318
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 0.0143124
POFUT4 protein O-fucosyltransferase 4 0.0142978
WASF1 WAS protein family, member 1 0.0142927
CDC42SE2 CDC42 small effector 2 0.0142275
PDZD2 PDZ domain containing 2 0.0142211
RPL30 ribosomal protein L30 0.0142199
QRICH1 glutamine-rich 1 0.0141996
ACTG1 actin gamma 1 0.0141322
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.014106
CNOT1 CCR4-NOT transcription complex, subunit 1 0.0140903
GCC2 GRIP and coiled-coil domain containing 2 0.0140866
CTSB cathepsin B 0.0140762
HIPK1 homeodomain interacting protein kinase 1 0.0140628
SOGA1 suppressor of glucose, autophagy associated 1 0.0140559
NT5DC1 5'-nucleotidase domain containing 1 0.0140283
FERMT2 fermitin family member 2 0.0140075
SCAF8 SR-related CTD-associated factor 8 0.0140049
HDGF hepatoma-derived growth factor 0.0140028
PIAS1 protein inhibitor of activated STAT, 1 0.013994
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 0.0139917
JPT1 Jupiter microtubule associated homolog 1 0.0139566
YBEY ybeY metallopeptidase (putative) 0.0139559
A4GALT alpha 1,4-galactosyltransferase 0.0139527
CPT1A carnitine palmitoyltransferase 1A (liver) 0.0139482
FCHSD2 FCH and double SH3 domains 2 0.0139338
SPIDR scaffolding protein involved in DNA repair 0.0139026
IL27RA interleukin 27 receptor, alpha 0.0139
CIZ1 CDKN1A interacting zinc finger protein 1 0.0138993
SH3D19 SH3 domain containing 19 0.0138926
IP6K2 inositol hexakisphosphate kinase 2 0.0138869
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.0138804
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 0.0138603
MZT2A mitotic spindle organizing protein 2A 0.0138507
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.0138497
STMN1 stathmin 1 0.0138382
TTC1 tetratricopeptide repeat domain 1 0.0138311
COL12A1 collagen, type XII, alpha 1 0.0138116
KAT6B K(lysine) acetyltransferase 6B 0.0137878
DEGS1 delta(4)-desaturase, sphingolipid 1 0.0137846
SLC16A6 solute carrier family 16, member 6 0.0137804
SPTBN1 spectrin, beta, non-erythrocytic 1 0.013762
SMG6 SMG6 nonsense mediated mRNA decay factor 0.0137134
LDOC1 leucine zipper, down-regulated in cancer 1 0.0137118
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.0137057
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.0137004
S100A13 S100 calcium binding protein A13 0.0136992
MBTD1 mbt domain containing 1 0.0136416
SIL1 SIL1 nucleotide exchange factor 0.0136316
SFSWAP splicing factor, suppressor of white-apricot family 0.0136224
AXIN1 axin 1 0.0136049
RPSA ribosomal protein SA 0.0135948
SCARB1 scavenger receptor class B, member 1 0.0135758
ITSN1 intersectin 1 (SH3 domain protein) 0.0135672
MUC16 mucin 16, cell surface associated 0.0135662
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.0135381
TPK1 thiamin pyrophosphokinase 1 0.013525

decreased expression

Symbol Name Standardized Value
SYTL2 synaptotagmin-like 2 -0.139915
KRT8 keratin 8, type II -0.139467
IGF1R insulin-like growth factor 1 receptor -0.120448
NRCAM neuronal cell adhesion molecule -0.116376
ERBB4 erb-b2 receptor tyrosine kinase 4 -0.1065
CUX1 cut-like homeobox 1 -0.100374
GATA3 GATA binding protein 3 -0.0996888
KRT18 keratin 18, type I -0.0887033
JARID2 jumonji, AT rich interactive domain 2 -0.0840705
NT5C2 5'-nucleotidase, cytosolic II -0.0686409
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.0683065
AGR2 anterior gradient 2 -0.067732
EVL Enah/Vasp-like -0.0651133
PBX3 pre-B-cell leukemia homeobox 3 -0.0631611
PARD6B par-6 family cell polarity regulator beta -0.0624087
RAD51B RAD51 paralog B -0.0601632
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0592586
PACS1 phosphofurin acidic cluster sorting protein 1 -0.0545792
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0526448
ATXN1 ataxin 1 -0.0507428
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.0503524
GFRA1 GDNF family receptor alpha 1 -0.050109
SULF2 sulfatase 2 -0.0491235
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -0.0483232
PCDH7 protocadherin 7 -0.0479642
EMP2 epithelial membrane protein 2 -0.0445344
ESR1 estrogen receptor 1 -0.0442025
SDK1 sidekick cell adhesion molecule 1 -0.0430484
SIPA1L1 signal-induced proliferation-associated 1 like 1 -0.042473
DTNA dystrobrevin, alpha -0.0387077
HMCN1 hemicentin 1 -0.0386058
KMT2C lysine (K)-specific methyltransferase 2C -0.0383546
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -0.03802
SPTSSB serine palmitoyltransferase, small subunit B -0.0378548
NRP1 neuropilin 1 -0.0377259
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.0374996
TMEM150C transmembrane protein 150C -0.0373081
CALCR calcitonin receptor -0.036776
PARD3 par-3 family cell polarity regulator -0.0365351
AREG amphiregulin -0.0363877
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase -0.0360931
RNF213 ring finger protein 213 -0.035929
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.0353078
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -0.0348514
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.0341683
PRKCE protein kinase C, epsilon -0.0341532
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.0332311
EPHA4 EPH receptor A4 -0.0329421
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.0324113
MACF1 microtubule-actin crosslinking factor 1 -0.0323602
MROH1 maestro heat-like repeat family member 1 -0.0323218
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.0322127
TMEM64 transmembrane protein 64 -0.031285
REEP5 receptor accessory protein 5 -0.0312638
PLXDC2 plexin domain containing 2 -0.0312489
ADCY1 adenylate cyclase 1 (brain) -0.0307506
KPNB1 karyopherin (importin) beta 1 -0.0305912
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.030305
LONRF2 LON peptidase N-terminal domain and ring finger 2 -0.0300612
ATRNL1 attractin-like 1 -0.0297669
JUP junction plakoglobin -0.029385
GRB2 growth factor receptor-bound protein 2 -0.0292769
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0286014
AK1 adenylate kinase 1 -0.0285453
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.0285382
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -0.0281332
MLPH melanophilin -0.0281219
GAN gigaxonin -0.0280102
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed -0.0280101
TUBD1 tubulin, delta 1 -0.0277891
ZFR zinc finger RNA binding protein -0.0276718
TRAPPC9 trafficking protein particle complex 9 -0.0270343
ALCAM activated leukocyte cell adhesion molecule -0.0269002
MBD5 methyl-CpG binding domain protein 5 -0.0267858
TUBA1B tubulin, alpha 1b -0.0266599
PDXK pyridoxal (pyridoxine, vitamin B6) kinase -0.0265864
CCDC47 coiled-coil domain containing 47 -0.0264769
LYPD6B LY6/PLAUR domain containing 6B -0.0263839
DSPP dentin sialophosphoprotein -0.026133
BRCA2 breast cancer 2, early onset -0.026131
GNA14 guanine nucleotide binding protein (G protein), alpha 14 -0.0259924
ZNF804B zinc finger protein 804B -0.0258701
CENPP centromere protein P -0.0257758
FOXO3 forkhead box O3 -0.0256883
SRRM2 serine/arginine repetitive matrix 2 -0.0256758
GOLGA4 golgin A4 -0.025405
TPR translocated promoter region, nuclear basket protein -0.0253463
CCSER1 coiled-coil serine-rich protein 1 -0.0252232
RUNX1 runt-related transcription factor 1 -0.0251188
NRDC nardilysin convertase -0.025091
EPN2 epsin 2 -0.0250119
FMN1 formin 1 -0.0248217
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.024757
ASCC3 activating signal cointegrator 1 complex subunit 3 -0.0245199
TOM1L2 target of myb1-like 2 (chicken) -0.024457
BICDL1 BICD family like cargo adaptor 1 -0.0244168
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -0.024415
KDM2A lysine (K)-specific demethylase 2A -0.0242532
RSF1 remodeling and spacing factor 1 -0.024227
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.0241654
DOP1B DOP1 leucine zipper like protein B -0.0241311
TCF25 transcription factor 25 (basic helix-loop-helix) -0.024058
DOCK1 dedicator of cytokinesis 1 -0.0239464
KDM2B lysine (K)-specific demethylase 2B -0.0238638
CAMK1D calcium/calmodulin-dependent protein kinase ID -0.0236773
NCAPG2 non-SMC condensin II complex, subunit G2 -0.023536
ADIPOR2 adiponectin receptor 2 -0.0233711
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A -0.0231535
GLCCI1 glucocorticoid induced 1 -0.0230657
DENND1A DENN/MADD domain containing 1A -0.0230165
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) -0.0230129
TUG1 taurine up-regulated 1 (non-protein coding) -0.0229466
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.022794
ACACA acetyl-CoA carboxylase alpha -0.0227764
DSCAM Down syndrome cell adhesion molecule -0.0227544
RPL23A ribosomal protein L23a -0.0227367
ATP9A ATPase, class II, type 9A -0.0227073
UGCG UDP-glucose ceramide glucosyltransferase -0.0225478
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.022436
CHD7 chromodomain helicase DNA binding protein 7 -0.022295
ZFAND6 zinc finger, AN1-type domain 6 -0.0222449
KCTD3 potassium channel tetramerization domain containing 3 -0.0219785
THBS1 thrombospondin 1 -0.0219698
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats -0.0218853
VASP vasodilator-stimulated phosphoprotein -0.0218823
ZMYM2 zinc finger, MYM-type 2 -0.0218436
FRMD5 FERM domain containing 5 -0.0217034
CA12 carbonic anhydrase XII -0.0216689
RTN4 reticulon 4 -0.0215271
SAPCD2 suppressor APC domain containing 2 -0.0213975
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.0212317
TMEM164 transmembrane protein 164 -0.0212258
RPL6 ribosomal protein L6 -0.0211119
TUBB4B tubulin, beta 4B class IVb -0.0210788
KRT19 keratin 19, type I -0.0209765
ITPRID2 ITPR interacting domain containing 2 -0.0209649
TRIO trio Rho guanine nucleotide exchange factor -0.0208619
SF3B2 splicing factor 3b, subunit 2, 145kDa -0.0207755
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.0207273
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein -0.0205723
ATAD2 ATPase family, AAA domain containing 2 -0.0204799
MAPK9 mitogen-activated protein kinase 9 -0.0204295
BAZ2A bromodomain adjacent to zinc finger domain, 2A -0.0203504
MYO5C myosin VC -0.0203128
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 -0.020236
EEIG1 estrogen-induced osteoclastogenesis regulator 1 -0.0201482
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.020141
TRPS1 trichorhinophalangeal syndrome I -0.0201173
TOP6BL TOP6B like initiator of meiotic double strand breaks -0.0200506
RINT1 RAD50 interactor 1 -0.0200483
ITGAV integrin, alpha V -0.0200199
MAP7 microtubule-associated protein 7 -0.0199408
SMC4 structural maintenance of chromosomes 4 -0.0199218
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0198783
OSBPL8 oxysterol binding protein-like 8 -0.0198625
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -0.0198475
NUP153 nucleoporin 153kDa -0.0198456
COP1 COP1 E3 ubiquitin ligase -0.0198334
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0198232
MACROD1 MACRO domain containing 1 -0.0197666
UBA6 ubiquitin-like modifier activating enzyme 6 -0.0197352
MASTL microtubule associated serine/threonine kinase-like -0.0197175
C6ORF141 chromosome 6 open reading frame 141 -0.0196553
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H -0.0195473
RANBP9 RAN binding protein 9 -0.0195166
WWP1 WW domain containing E3 ubiquitin protein ligase 1 -0.019403
MIDN midnolin -0.0193549
SIK3 SIK family kinase 3 -0.0193503
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 -0.0193046
UBTF upstream binding transcription factor, RNA polymerase I -0.0193035
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 -0.0192594
TRIQK triple QxxK/R motif containing -0.0192532
EEA1 early endosome antigen 1 -0.0192106
CANX calnexin -0.019197
TIAM2 T-cell lymphoma invasion and metastasis 2 -0.0191176
NSD1 nuclear receptor binding SET domain protein 1 -0.01911
BARD1 BRCA1 associated RING domain 1 -0.0189928
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 -0.0189418
GABPB2 GA binding protein transcription factor, beta subunit 2 -0.0188798
PLK2 polo-like kinase 2 -0.0188588
NHSL1 NHS-like 1 -0.0188446
BCAS1 breast carcinoma amplified sequence 1 -0.0188365
ARHGAP35 Rho GTPase activating protein 35 -0.0188158
JMJD1C jumonji domain containing 1C -0.0187598
FGF13 fibroblast growth factor 13 -0.0187585
SHANK2 SH3 and multiple ankyrin repeat domains 2 -0.0187282
TOPBP1 topoisomerase (DNA) II binding protein 1 -0.0186765
FAM120B family with sequence similarity 120B -0.0186575
RC3H2 ring finger and CCCH-type domains 2 -0.0186138
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) -0.0186129
NEMF nuclear export mediator factor -0.0185638
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.018518
SCRN1 secernin 1 -0.0184739
NCKAP5 NCK-associated protein 5 -0.0184725
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0184603
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.0183912
DHDDS dehydrodolichyl diphosphate synthase -0.0183333
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.0183299
TMF1 TATA element modulatory factor 1 -0.0183297
CCT7 chaperonin containing TCP1, subunit 7 (eta) -0.0182918
ITSN2 intersectin 2 -0.0182694
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha -0.0180194
SYT1 synaptotagmin I -0.0179912
ADAT1 adenosine deaminase, tRNA-specific 1 -0.0179802
TATDN1 TatD DNase domain containing 1 -0.0179696
STC1 stanniocalcin 1 -0.0178822
CDC14A cell division cycle 14A -0.0178624
USP48 ubiquitin specific peptidase 48 -0.01778
DCAF10 DDB1 and CUL4 associated factor 10 -0.017762
TPT1 tumor protein, translationally-controlled 1 -0.0177047
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) -0.0176148
ZBTB7A zinc finger and BTB domain containing 7A -0.0175224
FANCA Fanconi anemia, complementation group A -0.0174931
CHD8 chromodomain helicase DNA binding protein 8 -0.0174716
DCAF6 DDB1 and CUL4 associated factor 6 -0.0174142
ANKRD11 ankyrin repeat domain 11 -0.0173947
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -0.0173789
IPO7 importin 7 -0.0173515
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0173306
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -0.0173275
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -0.0173005
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains -0.0172896
IDI1 isopentenyl-diphosphate delta isomerase 1 -0.0172055
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 -0.0171412
MYO1B myosin IB -0.017066
TNPO2 transportin 2 -0.0170079
CLTC clathrin, heavy chain (Hc) -0.0169916
SYNJ1 synaptojanin 1 -0.0169716
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin -0.0169481
DST dystonin -0.0169275
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) -0.016896
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit -0.0168525
TMCC1 transmembrane and coiled-coil domain family 1 -0.016836
DPEP2 dipeptidase 2 -0.016771
SKIC3 SKI3 subunit of superkiller complex -0.0167468
GLO1 glyoxalase I -0.0167202
USP22 ubiquitin specific peptidase 22 -0.016675
KMT2E lysine (K)-specific methyltransferase 2E -0.0166667
RPL4 ribosomal protein L4 -0.0166649
EIF5 eukaryotic translation initiation factor 5 -0.016614
DCTN4 dynactin 4 (p62) -0.0166022
KDM3B lysine (K)-specific demethylase 3B -0.0165471
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 -0.0165383
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -0.0165083
SPICE1 spindle and centriole associated protein 1 -0.0164985
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.0164886
ANAPC1 anaphase promoting complex subunit 1 -0.0164806
RAB5A RAB5A, member RAS oncogene family -0.0164514
HMGB1 high mobility group box 1 -0.0164373
TIAM1 T-cell lymphoma invasion and metastasis 1 -0.0164179
BRI3BP BRI3 binding protein -0.0162193
SIDT1 SID1 transmembrane family, member 1 -0.0162188
EML5 echinoderm microtubule associated protein like 5 -0.0161995
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -0.0161786
DLG5 discs, large homolog 5 (Drosophila) -0.0161638
CRYBG1 crystallin beta-gamma domain containing 1 -0.0160955
TRAF3 TNF receptor-associated factor 3 -0.0160634
NUP205 nucleoporin 205kDa -0.0160424
INTS2 integrator complex subunit 2 -0.0160423
TTC17 tetratricopeptide repeat domain 17 -0.0160387
GATAD2A GATA zinc finger domain containing 2A -0.0160308
RBM39 RNA binding motif protein 39 -0.0160115
SUSD6 sushi domain containing 6 -0.0160057
ATP11C ATPase, class VI, type 11C -0.0159956
RBM14-RBM4 RBM14-RBM4 readthrough -0.0159773
SND1 staphylococcal nuclease and tudor domain containing 1 -0.0159736
SLF2 SMC5-SMC6 complex localization factor 2 -0.0159147
ZNF710 zinc finger protein 710 -0.0159048
STARD13 StAR-related lipid transfer (START) domain containing 13 -0.0158735
GALK2 galactokinase 2 -0.0158696
ZDHHC12 zinc finger, DHHC-type containing 12 -0.0158671
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.015863
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 -0.0158312
MCM4 minichromosome maintenance complex component 4 -0.0157533
GPBP1L1 GC-rich promoter binding protein 1-like 1 -0.0157501
CLASP1 cytoplasmic linker associated protein 1 -0.0157212
TMEM63A transmembrane protein 63A -0.0157092
RNASE3 ribonuclease, RNase A family, 3 -0.0156714
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.015606
PPP1R15B protein phosphatase 1, regulatory subunit 15B -0.0155932
ERCC6L2 excision repair cross-complementation group 6-like 2 -0.0155826
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -0.0155651
ANO6 anoctamin 6 -0.0155263
PRDX1 peroxiredoxin 1 -0.0155261
MYO10 myosin X -0.0155093
MCC mutated in colorectal cancers -0.0155043
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.0154306
FARSA phenylalanyl-tRNA synthetase, alpha subunit -0.0154124
TMEM87B transmembrane protein 87B -0.0154121
NUMB numb homolog (Drosophila) -0.0154018
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 -0.0153856
COL4A5 collagen, type IV, alpha 5 -0.0153718
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -0.0153611
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -0.0153554
HNRNPF heterogeneous nuclear ribonucleoprotein F -0.0153237
TMEM178B transmembrane protein 178B -0.0153006
CAV1 caveolin 1, caveolae protein, 22kDa -0.0152824
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0152646
ZMYND11 zinc finger, MYND-type containing 11 -0.0152376
SLC22A23 solute carrier family 22, member 23 -0.0152052
PBX1 pre-B-cell leukemia homeobox 1 -0.0151831
MARK4 MAP/microtubule affinity-regulating kinase 4 -0.0151738
SQLE squalene epoxidase -0.015159
SCAMP2 secretory carrier membrane protein 2 -0.0151564
HDAC2 histone deacetylase 2 -0.0151542
SAMD8 sterile alpha motif domain containing 8 -0.0151402
PTPRJ protein tyrosine phosphatase, receptor type, J -0.0151328
CKAP5 cytoskeleton associated protein 5 -0.0150951
PGRMC2 progesterone receptor membrane component 2 -0.0150669
TASOR2 transcription activation suppressor family member 2 -0.0150392
RPS18 ribosomal protein S18 -0.015039
KPNA4 karyopherin alpha 4 (importin alpha 3) -0.0149898
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit -0.0149829
FBXO11 F-box protein 11 -0.0149775
EPB41L5 erythrocyte membrane protein band 4.1 like 5 -0.0149424
UBE2B ubiquitin-conjugating enzyme E2B -0.0149108
TACSTD2 tumor-associated calcium signal transducer 2 -0.0148976
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 -0.0148727
RANGAP1 Ran GTPase activating protein 1 -0.014868
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -0.0148534
SCAPER S-phase cyclin A-associated protein in the ER -0.0148396
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -0.0148151
TYK2 tyrosine kinase 2 -0.0148034
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 -0.0147715
ANKLE2 ankyrin repeat and LEM domain containing 2 -0.014709
ASCC1 activating signal cointegrator 1 complex subunit 1 -0.0146956
SUZ12 SUZ12 polycomb repressive complex 2 subunit -0.0146956
POU2F1 POU class 2 homeobox 1 -0.0146803
NUP98 nucleoporin 98kDa -0.0146793
CAPN1 calpain 1, (mu/I) large subunit -0.0146156
ANKRD50 ankyrin repeat domain 50 -0.0146086
FAM217B family with sequence similarity 217, member B -0.0145602
PLXND1 plexin D1 -0.0145479
STK38 serine/threonine kinase 38 -0.0145397
PRKD2 protein kinase D2 -0.0145325
SYAP1 synapse associated protein 1 -0.0145241
SNX8 sorting nexin 8 -0.014479
RBM4 RNA binding motif protein 4 -0.0143881
KIAA1671 KIAA1671 -0.0143796
RYBP RING1 and YY1 binding protein -0.0143777
ISG15 ISG15 ubiquitin-like modifier -0.0143732
GDI2 GDP dissociation inhibitor 2 -0.0143408
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) -0.0142824
KPNA1 karyopherin alpha 1 (importin alpha 5) -0.0142659
NPDC1 neural proliferation, differentiation and control, 1 -0.0142577
BIRC6 baculoviral IAP repeat containing 6 -0.0142242
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans) -0.0142085
STRN3 striatin, calmodulin binding protein 3 -0.0141811
RC3H1 ring finger and CCCH-type domains 1 -0.0141636
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -0.01415
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa -0.0141464
CLIP1 CAP-GLY domain containing linker protein 1 -0.014109
CDYL chromodomain protein, Y-like -0.0140841
RIGI RNA sensor RIG-I -0.014082
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase -0.0140751
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa -0.0140168
FN1 fibronectin 1 -0.0140054
RTN4RL1 reticulon 4 receptor-like 1 -0.0140034
SLC35E1 solute carrier family 35, member E1 -0.0140007
LGALS12 lectin, galactoside-binding, soluble, 12 -0.0139807
DPYD dihydropyrimidine dehydrogenase -0.0139589
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.0139347
CNIH4 cornichon family AMPA receptor auxiliary protein 4 -0.013921
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -0.0139194
FANCI Fanconi anemia, complementation group I -0.013912
AKAP8L A kinase (PRKA) anchor protein 8-like -0.0138996
TMOD3 tropomodulin 3 (ubiquitous) -0.0138945
RNF130 ring finger protein 130 -0.0138264
C1ORF21 chromosome 1 open reading frame 21 -0.0138074
ZIC1 Zic family member 1 -0.0138008
UBC ubiquitin C -0.013783
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) -0.0137428
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 -0.0137392
ZBTB4 zinc finger and BTB domain containing 4 -0.0137269
PRRC2C proline-rich coiled-coil 2C -0.0137216
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase -0.0137187
STRBP spermatid perinuclear RNA binding protein -0.0136759
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.0136521
COPE coatomer protein complex, subunit epsilon -0.0136437
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 -0.0136342
NTN1 netrin 1 -0.0136133
FANCM Fanconi anemia, complementation group M -0.0135777
UBA2 ubiquitin-like modifier activating enzyme 2 -0.0135592
ANKRD17 ankyrin repeat domain 17 -0.013555
ABHD12 abhydrolase domain containing 12 -0.0135489
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -0.0135182
BCL2 B-cell CLL/lymphoma 2 -0.0134986
APOD apolipoprotein D -0.0134877
ABHD18 abhydrolase domain containing 18 -0.0134844
DPY19L4 dpy-19-like 4 (C. elegans) -0.0134641
ADCY9 adenylate cyclase 9 -0.0134492
REPS1 RALBP1 associated Eps domain containing 1 -0.013438
RARS2 arginyl-tRNA synthetase 2, mitochondrial -0.0134113
IRS1 insulin receptor substrate 1 -0.0133736
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -0.0133703
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -0.0133607
E2F3 E2F transcription factor 3 -0.0133496
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.0133479
ZC3H7B zinc finger CCCH-type containing 7B -0.0133236
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0133099
CDK17 cyclin-dependent kinase 17 -0.0132968
MAP3K20 mitogen-activated protein kinase kinase kinase 20 -0.0132885
PEAK1 pseudopodium-enriched atypical kinase 1 -0.0132884
THRB thyroid hormone receptor, beta -0.0132833
AP1M2 adaptor-related protein complex 1, mu 2 subunit -0.013262
CYFIP1 cytoplasmic FMR1 interacting protein 1 -0.0132403
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0132152
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 -0.0131918
FNDC3B fibronectin type III domain containing 3B -0.0131329
ARHGAP24 Rho GTPase activating protein 24 -0.0131176
DOCK6 dedicator of cytokinesis 6 -0.0130964
BAG6 BCL2-associated athanogene 6 -0.0130925
SCLT1 sodium channel and clathrin linker 1 -0.0130809
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -0.013069
NIPAL2 NIPA-like domain containing 2 -0.0130394
ENAH enabled homolog (Drosophila) -0.0130161
FKBP3 FK506 binding protein 3, 25kDa -0.0129785
SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10 -0.0129612
RCOR1 REST corepressor 1 -0.0129595
MREG melanoregulin -0.012951
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -0.0129084
PFKP phosphofructokinase, platelet -0.0128996
USP24 ubiquitin specific peptidase 24 -0.0128704
RARG retinoic acid receptor, gamma -0.0128695
C2CD3 C2 calcium-dependent domain containing 3 -0.0128533
ARHGAP12 Rho GTPase activating protein 12 -0.012805
SPIRE1 spire-type actin nucleation factor 1 -0.0127659
SON SON DNA binding protein -0.0127532
TUT7 terminal uridylyl transferase 7 -0.012753
OXR1 oxidation resistance 1 -0.0127518
PHTF1 putative homeodomain transcription factor 1 -0.0127446
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.0127431
NLN neurolysin (metallopeptidase M3 family) -0.0127362
TMED4 transmembrane emp24 protein transport domain containing 4 -0.0127349
VSIG10 V-set and immunoglobulin domain containing 10 -0.0127224
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) -0.012719
FRYL FRY-like -0.0126871
SKA2 spindle and kinetochore associated complex subunit 2 -0.0126854
ZNF277 zinc finger protein 277 -0.0126686
CD63 CD63 molecule -0.0126559
SMAD2 SMAD family member 2 -0.012631
QSER1 glutamine and serine rich 1 -0.0126167
FAM193B family with sequence similarity 193, member B -0.0126165
MYO6 myosin VI -0.0126043
UBR2 ubiquitin protein ligase E3 component n-recognin 2 -0.0125969
ZWILCH zwilch kinetochore protein -0.0125605
SACK1B scaffolding CK1 anchoring protein B -0.0125374
CHD9 chromodomain helicase DNA binding protein 9 -0.0125279
NBPF1 neuroblastoma breakpoint family, member 1 -0.012497
ZNF75D zinc finger protein 75D -0.0124915
AFDN afadin, adherens junction formation factor -0.0124718
VDAC1 voltage-dependent anion channel 1 -0.0124615
GON4L gon-4-like (C. elegans) -0.012443
EPHA7 EPH receptor A7 -0.0124254
NFIB nuclear factor I/B -0.0123998
ECPAS Ecm29 proteasome adaptor and scaffold -0.012372
LRRC75A leucine rich repeat containing 75A -0.0123695
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 -0.0123319
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0123021
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha -0.0122765
ALKBH5 AlkB family member 5, RNA demethylase -0.0122733
PRSS23 protease, serine, 23 -0.0122372
FXYD3 FXYD domain containing ion transport regulator 3 -0.0122217
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -0.0122152
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -0.0122117
SYCP2 synaptonemal complex protein 2 -0.0122072
PAWR PRKC, apoptosis, WT1, regulator -0.0122015
PRXL2A peroxiredoxin like 2A -0.0121894
TPST1 tyrosylprotein sulfotransferase 1 -0.0121811
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.0121422
GPSM2 G-protein signaling modulator 2 -0.0121042
SHARPIN SHANK-associated RH domain interactor -0.0120952
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) -0.0120747
RPS14 ribosomal protein S14 -0.0120605
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) -0.0120558
SP2 Sp2 transcription factor -0.0120558
CLIC4 chloride intracellular channel 4 -0.0120522
RNF24 ring finger protein 24 -0.0120489
FIRRM FIGNL1 interacting regulator of recombination and mitosis -0.0120266
TOGARAM1 TOG array regulator of axonemal microtubules 1 -0.0120131
ATXN7 ataxin 7 -0.0120066
TONSL tonsoku-like, DNA repair protein -0.0120031
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -0.0119914
EXD3 exonuclease 3'-5' domain containing 3 -0.0119765
PTOV1 prostate tumor overexpressed 1 -0.0119708
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase -0.0119476
ZDHHC7 zinc finger, DHHC-type containing 7 -0.0119049
ZFYVE16 zinc finger, FYVE domain containing 16 -0.0118715
RFWD3 ring finger and WD repeat domain 3 -0.0118663
SPATA13 spermatogenesis associated 13 -0.0118647
COMMD4 COMM domain containing 4 -0.0118566
UBE2K ubiquitin-conjugating enzyme E2K -0.0118252
CLDN4 claudin 4 -0.0118214
TGFB1 transforming growth factor, beta 1 -0.0118094
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -0.0117994
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.0117986
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0117948
MAPK6 mitogen-activated protein kinase 6 -0.011785
LRP10 low density lipoprotein receptor-related protein 10 -0.0117697
ZNF394 zinc finger protein 394 -0.011759