MCF7_GSK-LSD1 2HCl_10µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description GSK-LSD1 2HCl 10µM perturbation in MCF7 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the MCF7_GSK-LSD1 2HCl_10µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.188879
NCOA3 nuclear receptor coactivator 3 0.185173
BCAS3 breast carcinoma amplified sequence 3 0.173766
TRIM37 tripartite motif containing 37 0.169464
TTC28 tetratricopeptide repeat domain 28 0.140612
OVOL2 ovo-like zinc finger 2 0.136021
CTSD cathepsin D 0.128273
PTPRG protein tyrosine phosphatase, receptor type, G 0.0944165
USP32 ubiquitin specific peptidase 32 0.0908279
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 0.0794019
IGFBP5 insulin-like growth factor binding protein 5 0.0767688
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.0684884
MSI2 musashi RNA-binding protein 2 0.0642964
GRHL2 grainyhead-like 2 (Drosophila) 0.0629694
FLNA filamin A, alpha 0.0627611
UGDH UDP-glucose 6-dehydrogenase 0.0618023
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 0.0610582
PKM pyruvate kinase, muscle 0.0582429
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 0.0576768
LDLR low density lipoprotein receptor 0.0562755
AOPEP aminopeptidase O (putative) 0.0552141
MYOF myoferlin 0.0531132
POGZ pogo transposable element with ZNF domain 0.0510144
PACS1 phosphofurin acidic cluster sorting protein 1 0.0507662
ZRANB3 zinc finger, RAN-binding domain containing 3 0.049505
KMT2A lysine (K)-specific methyltransferase 2A 0.0487585
TPM4 tropomyosin 4 0.0485921
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.048054
PAWR PRKC, apoptosis, WT1, regulator 0.0468827
NBEA neurobeachin 0.046676
HSPB1 heat shock 27kDa protein 1 0.0442859
HIP1 huntingtin interacting protein 1 0.0424188
ZMYND8 zinc finger, MYND-type containing 8 0.042072
AUTS2 autism susceptibility candidate 2 0.0414976
C14ORF132 chromosome 14 open reading frame 132 0.0410424
PHACTR4 phosphatase and actin regulator 4 0.0396831
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.0388417
MACROD2 MACRO domain containing 2 0.0384646
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.0378134
RABGAP1L RAB GTPase activating protein 1-like 0.0373443
NRG3 neuregulin 3 0.0366235
DSTN destrin (actin depolymerizing factor) 0.0366109
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.0364238
MUC1 mucin 1, cell surface associated 0.0359153
DIAPH2 diaphanous-related formin 2 0.0357713
DNMBP dynamin binding protein 0.0352658
GPC6 glypican 6 0.0352577
SRPK2 SRSF protein kinase 2 0.0352188
R3HDM1 R3H domain containing 1 0.0350643
CLIC4 chloride intracellular channel 4 0.0347208
TTBK2 tau tubulin kinase 2 0.0337135
SPIDR scaffolding protein involved in DNA repair 0.0333922
KDM5B lysine (K)-specific demethylase 5B 0.0332261
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0329601
PTPRK protein tyrosine phosphatase, receptor type, K 0.0325265
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0321443
CEMIP2 cell migration inducing hyaluronidase 2 0.0320584
LURAP1L leucine rich adaptor protein 1-like 0.0318758
MUC16 mucin 16, cell surface associated 0.0318046
PPP1R13B protein phosphatase 1, regulatory subunit 13B 0.0314976
CHD9 chromodomain helicase DNA binding protein 9 0.0314403
COL5A1 collagen, type V, alpha 1 0.0310815
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.0308416
RHEB Ras homolog enriched in brain 0.0307605
RHOBTB3 Rho-related BTB domain containing 3 0.0307294
SQLE squalene epoxidase 0.03064
LRMDA leucine rich melanocyte differentiation associated 0.0305643
CCDC170 coiled-coil domain containing 170 0.0301324
SBF2 SET binding factor 2 0.0299836
MPHOSPH9 M-phase phosphoprotein 9 0.0299448
NCKAP5 NCK-associated protein 5 0.0297849
RAD51C RAD51 paralog C 0.0296715
XBP1 X-box binding protein 1 0.0295484
IGFBP4 insulin-like growth factor binding protein 4 0.0294867
PDLIM7 PDZ and LIM domain 7 (enigma) 0.0294729
SPTSSB serine palmitoyltransferase, small subunit B 0.0282607
TSPAN12 tetraspanin 12 0.0278282
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.0276759
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.0276032
NECTIN2 nectin cell adhesion molecule 2 0.0274142
STARD10 StAR-related lipid transfer (START) domain containing 10 0.0271143
TMEM135 transmembrane protein 135 0.0268029
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 0.0267377
TUFT1 tuftelin 1 0.026553
CSDE1 cold shock domain containing E1, RNA-binding 0.0264829
FGF12 fibroblast growth factor 12 0.0264756
STC2 stanniocalcin 2 0.0264043
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.026135
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.0259837
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.0257409
ENSA endosulfine alpha 0.0256555
PDS5B PDS5 cohesin associated factor B 0.0255072
RBM47 RNA binding motif protein 47 0.0253625
NBPF15 neuroblastoma breakpoint family, member 15 0.025291
NPNT nephronectin 0.025217
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.025071
ACTN4 actinin, alpha 4 0.0249036
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 0.024875
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.0248376
ATXN7 ataxin 7 0.0247951
AHNAK2 AHNAK nucleoprotein 2 0.0247791
DGKH diacylglycerol kinase, eta 0.0245088
IQGAP1 IQ motif containing GTPase activating protein 1 0.0243131
DTNBP1 dystrobrevin binding protein 1 0.0242985
UIMC1 ubiquitin interaction motif containing 1 0.024184
GREB1L growth regulation by estrogen in breast cancer-like 0.0241069
XPO1 exportin 1 0.0240887
TMPRSS4 transmembrane protease, serine 4 0.0240801
VMP1 vacuole membrane protein 1 0.0239395
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 0.0238437
MAML3 mastermind-like 3 (Drosophila) 0.0237778
TRIM33 tripartite motif containing 33 0.0237223
MALRD1 MAM and LDL receptor class A domain containing 1 0.0236595
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0236367
POLK polymerase (DNA directed) kappa 0.0236253
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0235261
SPNS1 spinster homolog 1 (Drosophila) 0.0234637
RTN3 reticulon 3 0.0233658
PARP14 poly (ADP-ribose) polymerase family, member 14 0.0233528
ANKRD11 ankyrin repeat domain 11 0.0232384
PRLR prolactin receptor 0.0232148
ZHX3 zinc fingers and homeoboxes 3 0.0231345
LOC112694756 uncharaterized LOC112694756 0.023099
LPP LIM domain containing preferred translocation partner in lipoma 0.0230449
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 0.0230352
CPA6 carboxypeptidase A6 0.0229903
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.02299
ELF2 E74-like factor 2 (ets domain transcription factor) 0.0228966
RGS6 regulator of G-protein signaling 6 0.0228926
NEO1 neogenin 1 0.022801
INSIG1 insulin induced gene 1 0.0226763
CSRP1 cysteine and glycine-rich protein 1 0.0225945
THSD4 thrombospondin, type I, domain containing 4 0.0224946
POLR1B polymerase (RNA) I polypeptide B, 128kDa 0.0224626
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0221566
ZBTB20 zinc finger and BTB domain containing 20 0.0220808
FAM13B family with sequence similarity 13, member B 0.0220328
CMSS1 cms1 ribosomal small subunit homolog (yeast) 0.0219364
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 0.0219264
NKAIN1 Na+/K+ transporting ATPase interacting 1 0.0218747
RAP1B RAP1B, member of RAS oncogene family 0.0218233
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 0.0217635
HM13 histocompatibility (minor) 13 0.0217308
SGMS1 sphingomyelin synthase 1 0.0216046
OSBPL9 oxysterol binding protein-like 9 0.0215904
STK38 serine/threonine kinase 38 0.0215582
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3 0.0215579
VAV3 vav 3 guanine nucleotide exchange factor 0.021538
SOS2 son of sevenless homolog 2 (Drosophila) 0.0214387
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0214159
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.021313
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.021214
SRRM2 serine/arginine repetitive matrix 2 0.0211623
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0211342
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.0209513
SH3D19 SH3 domain containing 19 0.02074
RPL18 ribosomal protein L18 0.0204981
AHCYL2 adenosylhomocysteinase-like 2 0.0204899
RHPN2 rhophilin, Rho GTPase binding protein 2 0.020485
QPRT quinolinate phosphoribosyltransferase 0.0204354
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.0204083
PDGFA platelet-derived growth factor alpha polypeptide 0.0203416
XPR1 xenotropic and polytropic retrovirus receptor 1 0.0200779
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0200423
HOOK2 hook microtubule-tethering protein 2 0.0200364
GRN granulin 0.0200346
DHCR7 7-dehydrocholesterol reductase 0.0199682
GNB5 guanine nucleotide binding protein (G protein), beta 5 0.0198751
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.0198722
SNED1 sushi, nidogen and EGF-like domains 1 0.019823
TPK1 thiamin pyrophosphokinase 1 0.019816
GRID1 glutamate receptor, ionotropic, delta 1 0.019659
KMT2E lysine (K)-specific methyltransferase 2E 0.0196528
ASS1 argininosuccinate synthase 1 0.0196096
STAU1 staufen double-stranded RNA binding protein 1 0.0196075
SEPTIN6 septin 6 0.0195722
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.019525
OPHN1 oligophrenin 1 0.0194445
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 0.0193827
FLNB filamin B, beta 0.0192874
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.0192694
PCNX1 pecanex 1 0.0192524
CERS4 ceramide synthase 4 0.0192279
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.0191864
SPDEF SAM pointed domain containing ETS transcription factor 0.0191472
TNRC18 trinucleotide repeat containing 18 0.0191158
MYADM myeloid-associated differentiation marker 0.0190752
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 0.0190746
MYH9 myosin, heavy chain 9, non-muscle 0.0190491
LMAN2 lectin, mannose-binding 2 0.0190406
USP34 ubiquitin specific peptidase 34 0.0190239
PGM2L1 phosphoglucomutase 2-like 1 0.0189599
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.0188489
CABLES1 Cdk5 and Abl enzyme substrate 1 0.0187486
NIN ninein (GSK3B interacting protein) 0.0186976
DENND5B DENN/MADD domain containing 5B 0.0186795
HSCB HscB mitochondrial iron-sulfur cluster co-chaperone 0.0186222
CRTC1 CREB regulated transcription coactivator 1 0.0185738
LGALS3 lectin, galactoside-binding, soluble, 3 0.0185485
CDK19 cyclin-dependent kinase 19 0.0185434
BTBD9 BTB (POZ) domain containing 9 0.0184763
MTCH2 mitochondrial carrier 2 0.018456
LMNA lamin A/C 0.0183364
SF3B3 splicing factor 3b, subunit 3, 130kDa 0.0183285
SSBP2 single-stranded DNA binding protein 2 0.0183252
ZEB1 zinc finger E-box binding homeobox 1 0.0183046
FHIT fragile histidine triad 0.0182462
ANKRD26 ankyrin repeat domain 26 0.0182326
NME7 NME/NM23 family member 7 0.0182272
SHISA5 shisa family member 5 0.0182224
DDHD1 DDHD domain containing 1 0.0181378
LITAF lipopolysaccharide-induced TNF factor 0.0181168
LPCAT3 lysophosphatidylcholine acyltransferase 3 0.0180867
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 0.0180717
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.0180472
AKAP8L A kinase (PRKA) anchor protein 8-like 0.0179831
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0179657
ESPN espin 0.0179637
ZNF644 zinc finger protein 644 0.0179604
NEK8 NIMA-related kinase 8 0.0179431
TAPBP TAP binding protein (tapasin) 0.0178849
PRKCH protein kinase C, eta 0.0178656
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.0178581
DHCR24 24-dehydrocholesterol reductase 0.0177399
SNX27 sorting nexin family member 27 0.0177042
S100A10 S100 calcium binding protein A10 0.0176945
FGD4 FYVE, RhoGEF and PH domain containing 4 0.0176856
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 0.0176037
ANXA6 annexin A6 0.0175949
PGR progesterone receptor 0.0175894
TSC22D1 TSC22 domain family, member 1 0.0175836
NOP58 NOP58 ribonucleoprotein 0.0175693
PCDHB16 protocadherin beta 16 0.0175323
SETD5 SET domain containing 5 0.0175187
GTF2I general transcription factor IIi 0.0174849
RBM15 RNA binding motif protein 15 0.0174842
HDAC8 histone deacetylase 8 0.0174467
KDM4B lysine (K)-specific demethylase 4B 0.017432
SEC62 SEC62 homolog (S. cerevisiae) 0.0174163
PALLD palladin, cytoskeletal associated protein 0.0173947
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.0173903
KIAA1958 KIAA1958 0.0173717
ASXL2 additional sex combs like transcriptional regulator 2 0.0172362
DMXL2 Dmx-like 2 0.017231
FYCO1 FYVE and coiled-coil domain containing 1 0.0172212
ZHX2 zinc fingers and homeoboxes 2 0.0172092
FAM168A family with sequence similarity 168, member A 0.0171667
ELOVL2 ELOVL fatty acid elongase 2 0.0171597
BAG3 BCL2-associated athanogene 3 0.0171499
TACC1 transforming, acidic coiled-coil containing protein 1 0.017112
NINL ninein-like 0.0171052
HACL2 2-hydroxyacyl-CoA lyase 2 0.0170973
PTPRS protein tyrosine phosphatase, receptor type, S 0.0170767
MTDH metadherin 0.0170128
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.0169545
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.0169214
HYOU1 hypoxia up-regulated 1 0.016842
UBXN4 UBX domain protein 4 0.0168277
GANAB glucosidase, alpha; neutral AB 0.0168088
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 0.0168053
GOLPH3L golgi phosphoprotein 3-like 0.0167786
DNM1L dynamin 1-like 0.0166985
PAN3 PAN3 poly(A) specific ribonuclease subunit 0.0166843
GCC2 GRIP and coiled-coil domain containing 2 0.0166424
NT5DC3 5'-nucleotidase domain containing 3 0.0166226
ATOSA atos homolog A 0.0166134
NEK7 NIMA-related kinase 7 0.0166044
NRF1 nuclear respiratory factor 1 0.0165793
TEX14 testis expressed 14 0.0165569
GRAMD1A GRAM domain containing 1A 0.01653
STAU2 staufen double-stranded RNA binding protein 2 0.0164814
ITSN2 intersectin 2 0.0164544
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.0164055
STK39 serine threonine kinase 39 0.016381
TBL1X transducin (beta)-like 1X-linked 0.0163755
SORT1 sortilin 1 0.0163621
PARD3B par-3 family cell polarity regulator beta 0.0163465
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.0162881
TBC1D12 TBC1 domain family, member 12 0.0162278
KRTAP11-1 keratin associated protein 11-1 0.0162169
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 0.0162073
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0161762
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.0161699
CDYL2 chromodomain protein, Y-like 2 0.0161509
FDPS farnesyl diphosphate synthase 0.0161356
SMIM14 small integral membrane protein 14 0.0161257
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 0.0160994
FNDC3A fibronectin type III domain containing 3A 0.0160899
NCOA1 nuclear receptor coactivator 1 0.0160191
TOM1L2 target of myb1-like 2 (chicken) 0.0159803
ELOVL5 ELOVL fatty acid elongase 5 0.0159487
GIPC1 GIPC PDZ domain containing family, member 1 0.0159055
RNFT2 ring finger protein, transmembrane 2 0.0158926
UBE2R2 ubiquitin-conjugating enzyme E2R 2 0.0158784
KDM6A lysine (K)-specific demethylase 6A 0.01586
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 0.0158505
SIAH2 siah E3 ubiquitin protein ligase 2 0.0158154
TMEM131L transmembrane 131 like 0.0157932
TIMP3 TIMP metallopeptidase inhibitor 3 0.015793
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 0.0157425
STARD13 StAR-related lipid transfer (START) domain containing 13 0.0157373
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 0.0157285
TANGO6 transport and golgi organization 6 homolog (Drosophila) 0.0157181
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.0156836
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.0156606
STK24 serine/threonine kinase 24 0.0156421
GSN gelsolin 0.0156128
MAPK8 mitogen-activated protein kinase 8 0.0155833
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 0.0155685
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0155524
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.0154995
DLC1 DLC1 Rho GTPase activating protein 0.0154489
CD47 CD47 molecule 0.015391
RGS17 regulator of G-protein signaling 17 0.0153731
POLR1A polymerase (RNA) I polypeptide A, 194kDa 0.0153728
YEATS2 YEATS domain containing 2 0.0152785
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 0.0152668
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 0.0152598
DCAF6 DDB1 and CUL4 associated factor 6 0.0152542
TRAFD1 TRAF-type zinc finger domain containing 1 0.0152492
ACIN1 apoptotic chromatin condensation inducer 1 0.0152388
ATF7IP activating transcription factor 7 interacting protein 0.0152167
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.0152019
FERMT2 fermitin family member 2 0.0152007
PRDX3 peroxiredoxin 3 0.0151324
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.0151098
CERT1 ceramide transporter 1 0.0150633
SACS sacsin molecular chaperone 0.0150574
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33 0.0150564
OSGIN2 oxidative stress induced growth inhibitor family member 2 0.0150539
IRS1 insulin receptor substrate 1 0.0150283
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.0150258
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.014996
DTNB dystrobrevin, beta 0.01498
CUEDC1 CUE domain containing 1 0.0149794
PRKG1 protein kinase, cGMP-dependent, type I 0.0149637
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.014889
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.0148811
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.0148434
IDI1 isopentenyl-diphosphate delta isomerase 1 0.0148329
HEATR6 HEAT repeat containing 6 0.0148142
CANX calnexin 0.0147922
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 0.0146954
H2AC6 H2A clustered histone 6 0.01467
PCNT pericentrin 0.0146474
ATM ATM serine/threonine kinase 0.0146283
HRNR hornerin 0.0146086
ATF7IP2 activating transcription factor 7 interacting protein 2 0.0145373
TRIM14 tripartite motif containing 14 0.0145177
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.0145135
PRPF40B PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) 0.0145005
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.0144871
PHKA2 phosphorylase kinase, alpha 2 (liver) 0.0144427
YBX3 Y box binding protein 3 0.0144351
NBAS neuroblastoma amplified sequence 0.0144113
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0144071
SOGA1 suppressor of glucose, autophagy associated 1 0.0143969
CEP112 centrosomal protein 112kDa 0.0143877
FRMD8 FERM domain containing 8 0.0143828
CEP170 centrosomal protein 170kDa 0.0143659
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 0.0143554
STIL SCL/TAL1 interrupting locus 0.0143233
UBN1 ubinuclein 1 0.0142899
SLC71A2 solute carrier family 71 member 2 0.0142774
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.0142723
FGF13 fibroblast growth factor 13 0.0142493
RFX3 regulatory factor X, 3 (influences HLA class II expression) 0.0141879
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.0141699
UBB ubiquitin B 0.0141215
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.0141075
AKAP10 A kinase (PRKA) anchor protein 10 0.0141014
SLC38A12 solute carrier family 38 member 12 0.0140617
SETD2 SET domain containing 2 0.0140587
TERF2IP telomeric repeat binding factor 2, interacting protein 0.01404
KIAA0825 KIAA0825 0.0140228
RBM6 RNA binding motif protein 6 0.0140201
NUCB2 nucleobindin 2 0.0140123
MUSK muscle, skeletal, receptor tyrosine kinase 0.0140113
TMEM131 transmembrane protein 131 0.0139565
LARS1 leucyl-tRNA synthetase 1 0.0139512
CD59 CD59 molecule, complement regulatory protein 0.0139328
PKN1 protein kinase N1 0.0138955
MAP2K2 mitogen-activated protein kinase kinase 2 0.0138953
RIGI RNA sensor RIG-I 0.0138711
TOB1 transducer of ERBB2, 1 0.0138596
RIPOR3 RIPOR family member 3 0.0138504
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 0.013839
CD151 CD151 molecule (Raph blood group) 0.013826
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 0.0138069
P3H1 prolyl 3-hydroxylase 1 0.0137717
SEC16A SEC16 homolog A (S. cerevisiae) 0.0137309
HEATR5A HEAT repeat containing 5A 0.0137258
SLC38A1 solute carrier family 38, member 1 0.013715
RPL14 ribosomal protein L14 0.0137141
MXD4 MAX dimerization protein 4 0.0137014
PCSK6 proprotein convertase subtilisin/kexin type 6 0.0136806
GOLGB1 golgin B1 0.0136631
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 0.0136479
HSH2D hematopoietic SH2 domain containing 0.0136361
CAMK2D calcium/calmodulin-dependent protein kinase II delta 0.0136355
BCL2 B-cell CLL/lymphoma 2 0.0136323
RAI1 retinoic acid induced 1 0.0135947
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.0135943
CAMKMT calmodulin-lysine N-methyltransferase 0.0135856
SEZ6L2 seizure related 6 homolog (mouse)-like 2 0.013554
HNRNPF heterogeneous nuclear ribonucleoprotein F 0.0135269
GDNF glial cell derived neurotrophic factor 0.0134776
IER5L immediate early response 5-like 0.0134629
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 0.0134444
ARID4A AT rich interactive domain 4A (RBP1-like) 0.0133713
ZMYM5 zinc finger, MYM-type 5 0.0133563
FUS FUS RNA binding protein 0.0133522
RPL23 ribosomal protein L23 0.0133369
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 0.013326
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.0132962
PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 0.013274
MEIS1 Meis homeobox 1 0.0132414
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.0132106
PDS5A PDS5 cohesin associated factor A 0.0131749
ATP11B ATPase, class VI, type 11B 0.0131553
KRIT1 KRIT1, ankyrin repeat containing 0.0131349
GOLGA4 golgin A4 0.013116
FCHSD2 FCH and double SH3 domains 2 0.013105
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.0131002
CHD6 chromodomain helicase DNA binding protein 6 0.013083
CERS2 ceramide synthase 2 0.0130419
LIMK2 LIM domain kinase 2 0.0130289
GSTM3 glutathione S-transferase mu 3 (brain) 0.0130288
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 0.0130265
CLU clusterin 0.0130214
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 0.0129923
BICDL1 BICD family like cargo adaptor 1 0.0129705
PDE3B phosphodiesterase 3B, cGMP-inhibited 0.0129684
MYB v-myb avian myeloblastosis viral oncogene homolog 0.0129628
HLTF helicase-like transcription factor 0.0129575
ACSS3 acyl-CoA synthetase short-chain family member 3 0.0129297
CCT7 chaperonin containing TCP1, subunit 7 (eta) 0.012897
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.0128943
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 0.0128495
SEM1 SEM1 26S proteasome subunit 0.0128222
MBTD1 mbt domain containing 1 0.0127632
TCEA2 transcription elongation factor A (SII), 2 0.0126904
TFRC transferrin receptor 0.0126768
PDZRN3 PDZ domain containing ring finger 3 0.0126455
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) 0.0126455
HELZ helicase with zinc finger 0.0126412
DPY19L1 dpy-19-like 1 (C. elegans) 0.0126023
REXO2 RNA exonuclease 2 0.0126007
LAMP1 lysosomal-associated membrane protein 1 0.0125534
SYTL4 synaptotagmin-like 4 0.0125159
CELF1 CUGBP, Elav-like family member 1 0.0125125
OSBPL10 oxysterol binding protein-like 10 0.0124968
CYSTM1 cysteine-rich transmembrane module containing 1 0.0124321
SH3KBP1 SH3-domain kinase binding protein 1 0.0124311
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0124262
SGPP1 sphingosine-1-phosphate phosphatase 1 0.0123894
NR6A1 nuclear receptor subfamily 6, group A, member 1 0.0123843
BLTP3B bridge-like lipid transfer protein family member 3B 0.0123831
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 0.0123509
PLCB4 phospholipase C, beta 4 0.0123391
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 0.0123274
RPAP2 RNA polymerase II associated protein 2 0.0123268
SH3GL1 SH3-domain GRB2-like 1 0.0123152
VCL vinculin 0.0122952
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 0.0122484
SDC1 syndecan 1 0.0122274
ANKRD50 ankyrin repeat domain 50 0.012219
MECP2 methyl CpG binding protein 2 0.0122166
TUBGCP2 tubulin, gamma complex associated protein 2 0.012188
TBCE tubulin folding cofactor E 0.0121695
ESRRA estrogen-related receptor alpha 0.012163
MTREX Mtr4 exosome RNA helicase 0.0121456
MFGE8 milk fat globule-EGF factor 8 protein 0.0121292
SMAD5 SMAD family member 5 0.0121012
IDE insulin-degrading enzyme 0.0120808
SQSTM1 sequestosome 1 0.012077
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.0120667
RNF10 ring finger protein 10 0.0120427
PRUNE2 prune homolog 2 (Drosophila) 0.0120375
EEA1 early endosome antigen 1 0.0119953
LHFPL2 lipoma HMGIC fusion partner-like 2 0.0119755
OLFM1 olfactomedin 1 0.0119468
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 0.0119411
VDAC2 voltage-dependent anion channel 2 0.0119397
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.0119385
STX5 syntaxin 5 0.0119368
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.0119345
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.0119266
PHF20 PHD finger protein 20 0.0119266
FOXK1 forkhead box K1 0.0119038
ESD esterase D 0.0119026
PCNX4 pecanex 4 0.0118971
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 0.0118825
ADGRA3 adhesion G protein-coupled receptor A3 0.0118369
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.0118279
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 0.0118229
THOC2 THO complex 2 0.0118137
PNISR PNN-interacting serine/arginine-rich protein 0.0117871
TSPAN15 tetraspanin 15 0.0117853
TRA2A transformer 2 alpha homolog (Drosophila) 0.0117827

decreased expression

Symbol Name Standardized Value
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.160683
SYTL2 synaptotagmin-like 2 -0.160089
EVL Enah/Vasp-like -0.138702
AGR2 anterior gradient 2 -0.101373
BPTF bromodomain PHD finger transcription factor -0.0918837
GFRA1 GDNF family receptor alpha 1 -0.090216
ATXN1 ataxin 1 -0.0762314
TRPS1 trichorhinophalangeal syndrome I -0.0721834
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.0719354
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 -0.0668794
PRR11 proline rich 11 -0.0624373
RPS3 ribosomal protein S3 -0.0578243
H3-3B H3.3 histone B -0.0574466
DSCAM Down syndrome cell adhesion molecule -0.0554728
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.053049
CLTC clathrin, heavy chain (Hc) -0.0529032
TFF1 trefoil factor 1 -0.0527409
ERBB4 erb-b2 receptor tyrosine kinase 4 -0.0512525
JARID2 jumonji, AT rich interactive domain 2 -0.050821
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.0504383
ITPRID2 ITPR interacting domain containing 2 -0.050428
CCND1 cyclin D1 -0.0500831
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.0498387
RPS6 ribosomal protein S6 -0.049417
MED13 mediator complex subunit 13 -0.0482015
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) -0.0475788
SDK1 sidekick cell adhesion molecule 1 -0.046348
PBX3 pre-B-cell leukemia homeobox 3 -0.0462552
BMP7 bone morphogenetic protein 7 -0.0460379
RPS19 ribosomal protein S19 -0.044576
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -0.0444352
TMBIM6 transmembrane BAX inhibitor motif containing 6 -0.0443413
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0434487
CALCR calcitonin receptor -0.0433003
EPHA4 EPH receptor A4 -0.0421708
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.0420115
MYO1B myosin IB -0.0413105
PARD6B par-6 family cell polarity regulator beta -0.0392989
KAT6B K(lysine) acetyltransferase 6B -0.0391752
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0390092
KRT18 keratin 18, type I -0.0380444
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0379611
RPL7A ribosomal protein L7a -0.0374224
ZFHX3 zinc finger homeobox 3 -0.0372818
SULF2 sulfatase 2 -0.0364944
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0360521
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0356604
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -0.035648
RPS2 ribosomal protein S2 -0.035642
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle -0.035135
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.0347457
ZFAND3 zinc finger, AN1-type domain 3 -0.0346308
GAN gigaxonin -0.0342023
ESR1 estrogen receptor 1 -0.0338261
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0336515
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0336162
BIRC6 baculoviral IAP repeat containing 6 -0.0336142
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase -0.0335459
NCAPD2 non-SMC condensin I complex, subunit D2 -0.0327395
RAB31 RAB31, member RAS oncogene family -0.0326363
RAD51B RAD51 paralog B -0.0326019
ATAD2 ATPase family, AAA domain containing 2 -0.0324106
RPL32 ribosomal protein L32 -0.0319737
RPLP1 ribosomal protein, large, P1 -0.0317502
ATXN7L1 ataxin 7-like 1 -0.0310903
PKP4 plakophilin 4 -0.0308663
SCAMP2 secretory carrier membrane protein 2 -0.0305529
HDLBP high density lipoprotein binding protein -0.0305201
TPX2 TPX2, microtubule-associated -0.0302728
CUX1 cut-like homeobox 1 -0.0302139
OLA1 Obg-like ATPase 1 -0.0301281
RPL23A ribosomal protein L23a -0.0300589
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.029988
CD81 CD81 molecule -0.02994
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.0297303
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -0.0297186
RABL6 RAB, member RAS oncogene family-like 6 -0.0294393
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0286866
DOCK1 dedicator of cytokinesis 1 -0.0282962
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0282779
RPLP2 ribosomal protein, large, P2 -0.0282716
SOX4 SRY (sex determining region Y)-box 4 -0.0282588
NCOA2 nuclear receptor coactivator 2 -0.0282391
RPS29 ribosomal protein S29 -0.0282248
HOMER2 homer scaffolding protein 2 -0.0282078
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.0280899
TPT1 tumor protein, translationally-controlled 1 -0.0279119
TUBB4B tubulin, beta 4B class IVb -0.0278395
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0278316
TOP1 topoisomerase (DNA) I -0.0276615
PRRC2B proline-rich coiled-coil 2B -0.0276486
SPATS2 spermatogenesis associated, serine-rich 2 -0.0276214
BSG basigin (Ok blood group) -0.0271222
LRP10 low density lipoprotein receptor-related protein 10 -0.0270583
RPLP0 ribosomal protein, large, P0 -0.0268459
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.0266459
ZNF609 zinc finger protein 609 -0.0264768
RCOR1 REST corepressor 1 -0.0262068
RPS17 ribosomal protein S17 -0.0261332
UBC ubiquitin C -0.0259808
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed -0.0257707
TET3 tet methylcytosine dioxygenase 3 -0.0257451
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0253625
EMP2 epithelial membrane protein 2 -0.0253513
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.0251941
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0250274
PPP6R2 protein phosphatase 6, regulatory subunit 2 -0.024986
TMEM64 transmembrane protein 64 -0.0248714
PTGES2 prostaglandin E synthase 2 -0.0248188
RPL8 ribosomal protein L8 -0.0246649
SMAD3 SMAD family member 3 -0.0246098
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 -0.024167
RPL37 ribosomal protein L37 -0.0241168
STRBP spermatid perinuclear RNA binding protein -0.0240408
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0239057
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB -0.0238604
PDE7A phosphodiesterase 7A -0.0237737
FAF1 Fas (TNFRSF6) associated factor 1 -0.023731
CDK6 cyclin-dependent kinase 6 -0.0236915
ADCY1 adenylate cyclase 1 (brain) -0.0236392
NUDCD3 NudC domain containing 3 -0.0235387
RPSA ribosomal protein SA -0.0235158
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0235111
GATA3 GATA binding protein 3 -0.0234912
EPB41L5 erythrocyte membrane protein band 4.1 like 5 -0.0232138
RSRC1 arginine/serine-rich coiled-coil 1 -0.0231934
LCOR ligand dependent nuclear receptor corepressor -0.0231194
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 -0.0230725
NVL nuclear VCP-like -0.0230114
RPL10A ribosomal protein L10a -0.0228673
NBEAL1 neurobeachin-like 1 -0.0228483
AP1G1 adaptor-related protein complex 1, gamma 1 subunit -0.0228046
GATAD2B GATA zinc finger domain containing 2B -0.0228022
FOXP1 forkhead box P1 -0.0227769
CHD7 chromodomain helicase DNA binding protein 7 -0.022676
ZDHHC20 zinc finger, DHHC-type containing 20 -0.0226716
YY1 YY1 transcription factor -0.0224588
MED13L mediator complex subunit 13-like -0.0224353
BRD4 bromodomain containing 4 -0.0223458
NCAPG2 non-SMC condensin II complex, subunit G2 -0.0221989
TMSB10 thymosin beta 10 -0.0220719
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -0.0220214
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0219557
JMJD1C jumonji domain containing 1C -0.0218092
WASF2 WAS protein family, member 2 -0.0217809
LRRC58 leucine rich repeat containing 58 -0.0217027
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.0217018
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) -0.0216896
EIF3A eukaryotic translation initiation factor 3, subunit A -0.0216774
PPP4R3A protein phosphatase 4 regulatory subunit 3A -0.0215999
MCM4 minichromosome maintenance complex component 4 -0.0214966
GPR107 G protein-coupled receptor 107 -0.0214735
BTBD7 BTB (POZ) domain containing 7 -0.0213707
PPP1R12A protein phosphatase 1, regulatory subunit 12A -0.0213119
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.0212966
MAP3K20 mitogen-activated protein kinase kinase kinase 20 -0.0212757
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.0212266
FANCI Fanconi anemia, complementation group I -0.0211299
CCNY cyclin Y -0.0211066
RAB6A RAB6A, member RAS oncogene family -0.0210118
RDX radixin -0.0209926
MCU mitochondrial calcium uniporter -0.0209323
ESRP1 epithelial splicing regulatory protein 1 -0.0208548
TMOD3 tropomodulin 3 (ubiquitous) -0.0208032
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -0.0206635
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0206548
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.0206389
RPL29 ribosomal protein L29 -0.0206186
EEF2 eukaryotic translation elongation factor 2 -0.0204773
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 -0.020434
FXYD3 FXYD domain containing ion transport regulator 3 -0.0203923
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -0.0203665
CLASP2 cytoplasmic linker associated protein 2 -0.0203533
MORF4L2 mortality factor 4 like 2 -0.0202802
NEBL nebulette -0.0202609
NCOR2 nuclear receptor corepressor 2 -0.0201128
REEP3 receptor accessory protein 3 -0.0198357
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0198152
RUNX1 runt-related transcription factor 1 -0.0197397
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 -0.0196545
HLA-E major histocompatibility complex, class I, E -0.019625
LONRF2 LON peptidase N-terminal domain and ring finger 2 -0.0196176
CCNK cyclin K -0.0195942
GPHN gephyrin -0.019579
UBTF upstream binding transcription factor, RNA polymerase I -0.0193942
TUG1 taurine up-regulated 1 (non-protein coding) -0.0193336
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 -0.0193139
ARHGAP11B Rho GTPase activating protein 11B -0.0191764
ZNF148 zinc finger protein 148 -0.0191698
CCNF cyclin F -0.0191076
PRDX5 peroxiredoxin 5 -0.0189798
MIS18BP1 MIS18 binding protein 1 -0.0189795
DNASE2 deoxyribonuclease II, lysosomal -0.0189292
SVIL supervillin -0.018832
DHDDS dehydrodolichyl diphosphate synthase -0.018778
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0187103
DIAPH1 diaphanous-related formin 1 -0.0187093
H1-10 H1.10 linker histone -0.0186951
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -0.0186622
NPAS3 neuronal PAS domain protein 3 -0.0186176
SYT1 synaptotagmin I -0.0186067
CKAP5 cytoskeleton associated protein 5 -0.01855
DAAM1 dishevelled associated activator of morphogenesis 1 -0.0185218
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.01848
ERC1 ELKS/RAB6-interacting/CAST family member 1 -0.0184569
CAPZB capping protein (actin filament) muscle Z-line, beta -0.0184209
ZNF107 zinc finger protein 107 -0.0181303
GABPB2 GA binding protein transcription factor, beta subunit 2 -0.0181022
ASTN2 astrotactin 2 -0.0180821
STRN3 striatin, calmodulin binding protein 3 -0.0180781
TMEM178B transmembrane protein 178B -0.0180478
MEGF9 multiple EGF-like-domains 9 -0.0179779
XPO6 exportin 6 -0.0178573
NRP1 neuropilin 1 -0.0178501
PRKCE protein kinase C, epsilon -0.0178173
DCAF10 DDB1 and CUL4 associated factor 10 -0.0178066
DSPP dentin sialophosphoprotein -0.017748
IFI6 interferon, alpha-inducible protein 6 -0.0177192
PA2G4 proliferation-associated 2G4, 38kDa -0.0175163
PUS7 pseudouridylate synthase 7 (putative) -0.0174637
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 -0.0174256
MYO16 myosin XVI -0.017379
SPIRE1 spire-type actin nucleation factor 1 -0.0173752
MAP3K13 mitogen-activated protein kinase kinase kinase 13 -0.0173689
SMC4 structural maintenance of chromosomes 4 -0.0172923
PATJ PATJ crumbs cell polarity complex component -0.0172705
RHOA ras homolog family member A -0.0172619
LRP1B low density lipoprotein receptor-related protein 1B -0.0171701
POC1B POC1 centriolar protein B -0.0171088
CNBP CCHC-type zinc finger, nucleic acid binding protein -0.0170411
SIDT1 SID1 transmembrane family, member 1 -0.0168783
RPS24 ribosomal protein S24 -0.0168529
NIPBL Nipped-B homolog (Drosophila) -0.0168184
MYO1E myosin IE -0.0167673
SERINC5 serine incorporator 5 -0.0167598
ENOSF1 enolase superfamily member 1 -0.0167433
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -0.0167428
RAD21 RAD21 homolog (S. pombe) -0.0167334
NAV2 neuron navigator 2 -0.0166895
NIPAL2 NIPA-like domain containing 2 -0.0166821
KIF4A kinesin family member 4A -0.0166798
CRYBG1 crystallin beta-gamma domain containing 1 -0.0166735
LRIF1 ligand dependent nuclear receptor interacting factor 1 -0.0166492
SARS2 seryl-tRNA synthetase 2, mitochondrial -0.0166354
RPL37A ribosomal protein L37a -0.0166167
SHISA9 shisa family member 9 -0.0165941
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) -0.016562
RANBP17 RAN binding protein 17 -0.0165616
BRI3BP BRI3 binding protein -0.016542
RORA RAR-related orphan receptor A -0.016526
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -0.0165222
GLCCI1 glucocorticoid induced 1 -0.0165207
NPDC1 neural proliferation, differentiation and control, 1 -0.0165107
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 -0.0164835
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -0.0164541
POTEF POTE ankyrin domain family, member F -0.0164534
MKI67 marker of proliferation Ki-67 -0.016424
USP53 ubiquitin specific peptidase 53 -0.016417
ZMYM2 zinc finger, MYM-type 2 -0.016348
RPL15 ribosomal protein L15 -0.0163338
AGO2 argonaute RISC catalytic component 2 -0.0163244
SND1 staphylococcal nuclease and tudor domain containing 1 -0.0163106
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0162483
NCKAP1 NCK-associated protein 1 -0.0162013
ITM2B integral membrane protein 2B -0.0161886
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 -0.0161256
YME1L1 YME1-like 1 ATPase -0.0161238
LARP4 La ribonucleoprotein domain family, member 4 -0.0160945
PCNX2 pecanex 2 -0.0160891
NSD1 nuclear receptor binding SET domain protein 1 -0.0160659
VAC14 Vac14 homolog (S. cerevisiae) -0.0160555
PCBP2 poly(rC) binding protein 2 -0.0160519
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 -0.0160505
PTDSS1 phosphatidylserine synthase 1 -0.0160182
AREG amphiregulin -0.0159893
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) -0.0159819
PTEN phosphatase and tensin homolog -0.0159546
SYNPO2 synaptopodin 2 -0.0159444
FBXO34 F-box protein 34 -0.0159417
NOTCH2 notch 2 -0.015916
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -0.0158774
RPL4 ribosomal protein L4 -0.0158657
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B -0.0158259
MICU1 mitochondrial calcium uptake 1 -0.0158175
CHEK2 checkpoint kinase 2 -0.0158088
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 -0.015807
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0157968
SAMD12 sterile alpha motif domain containing 12 -0.0157935
MBOAT2 membrane bound O-acyltransferase domain containing 2 -0.0157699
SPOP speckle-type POZ protein -0.0157148
PCLO piccolo presynaptic cytomatrix protein -0.0157007
ZNF804B zinc finger protein 804B -0.015679
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 -0.0156573
ADGRG6 adhesion G protein-coupled receptor G6 -0.0156337
MYO1D myosin ID -0.0156329
COL4A5 collagen, type IV, alpha 5 -0.0156009
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -0.0155636
RPL21 ribosomal protein L21 -0.0154968
LCORL ligand dependent nuclear receptor corepressor-like -0.015477
EDF1 endothelial differentiation-related factor 1 -0.0154425
HDGFL3 HDGF like 3 -0.0153663
RBM33 RNA binding motif protein 33 -0.015356
CHD1 chromodomain helicase DNA binding protein 1 -0.0153514
WWC1 WW and C2 domain containing 1 -0.0153379
IGF1R insulin-like growth factor 1 receptor -0.0153185
MYO5C myosin VC -0.0152147
EIF3H eukaryotic translation initiation factor 3, subunit H -0.0152122
LARP4B La ribonucleoprotein domain family, member 4B -0.0152081
RSRC2 arginine/serine-rich coiled-coil 2 -0.0151855
GNA14 guanine nucleotide binding protein (G protein), alpha 14 -0.0151781
FANCA Fanconi anemia, complementation group A -0.0151773
SMG7 SMG7 nonsense mediated mRNA decay factor -0.0151704
SCFD2 sec1 family domain containing 2 -0.0151528
CFDP1 craniofacial development protein 1 -0.0151273
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -0.0151177
AHDC1 AT hook, DNA binding motif, containing 1 -0.0151055
DPEP2 dipeptidase 2 -0.0150846
CDT1 chromatin licensing and DNA replication factor 1 -0.0149799
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 -0.0149788
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -0.0149608
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.0149544
COX6C cytochrome c oxidase subunit VIc -0.0149258
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 -0.0149223
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -0.0149199
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -0.0149171
GPSM2 G-protein signaling modulator 2 -0.0149009
CCSER2 coiled-coil serine-rich protein 2 -0.0148303
TLK1 tousled-like kinase 1 -0.0148238
CNOT6 CCR4-NOT transcription complex, subunit 6 -0.0147806
C1ORF21 chromosome 1 open reading frame 21 -0.0147534
PLK2 polo-like kinase 2 -0.0147359
GNA12 guanine nucleotide binding protein (G protein) alpha 12 -0.0147337
CLIC1 chloride intracellular channel 1 -0.0146989
ALMS1 Alstrom syndrome protein 1 -0.014688
RPL12 ribosomal protein L12 -0.014686
RMDN1 regulator of microtubule dynamics 1 -0.0146449
APLP2 amyloid beta (A4) precursor-like protein 2 -0.0146116
RFWD3 ring finger and WD repeat domain 3 -0.0146062
MACF1 microtubule-actin crosslinking factor 1 -0.0145106
MPG N-methylpurine-DNA glycosylase -0.0144457
EPN2 epsin 2 -0.014426
GOLPH3 golgi phosphoprotein 3 (coat-protein) -0.0144038
RPN2 ribophorin II -0.0143898
ASF1B anti-silencing function 1B histone chaperone -0.0143188
EXOC6B exocyst complex component 6B -0.0143162
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.0142789
STRN striatin, calmodulin binding protein -0.0142478
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.01422
KPNB1 karyopherin (importin) beta 1 -0.0142004
NUP153 nucleoporin 153kDa -0.0141826
MRTFB myocardin related transcription factor B -0.0141805
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 -0.0141744
G2E3 G2/M-phase specific E3 ubiquitin protein ligase -0.0141665
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0141367
CHD8 chromodomain helicase DNA binding protein 8 -0.0140559
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa -0.0140375
ZFC3H1 zinc finger, C3H1-type containing -0.0140356
DIAPH3 diaphanous-related formin 3 -0.0139817
TBC1D5 TBC1 domain family, member 5 -0.0139802
RPL19 ribosomal protein L19 -0.0139081
BCL9L B-cell CLL/lymphoma 9-like -0.0139062
WAPL WAPL cohesin release factor -0.0138895
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 -0.0138263
WDR20 WD repeat domain 20 -0.0138247
GDI2 GDP dissociation inhibitor 2 -0.0137827
CA12 carbonic anhydrase XII -0.0137817
CBX5 chromobox homolog 5 -0.0137499
IFI27 interferon, alpha-inducible protein 27 -0.0137492
MIDEAS mitotic deacetylase associated SANT domain protein -0.0137386
COX7C cytochrome c oxidase subunit VIIc -0.013733
ERP29 endoplasmic reticulum protein 29 -0.0137248
ADNP activity-dependent neuroprotector homeobox -0.0136977
TTC7A tetratricopeptide repeat domain 7A -0.0136938
KIF2A kinesin heavy chain member 2A -0.0136677
MYO6 myosin VI -0.0136346
PTMA prothymosin, alpha -0.0135933
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.013576
AKAP13 A kinase (PRKA) anchor protein 13 -0.0135703
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like -0.0135597
SASH1 SAM and SH3 domain containing 1 -0.0135483
VTA1 vesicle (multivesicular body) trafficking 1 -0.0135473
MAP7 microtubule-associated protein 7 -0.0135327
GPATCH2 G patch domain containing 2 -0.013515
TMPO thymopoietin -0.0135144
CDC123 cell division cycle 123 -0.0135092
PUM2 pumilio RNA-binding family member 2 -0.0134895
RAB7A RAB7A, member RAS oncogene family -0.0134887
RPS25 ribosomal protein S25 -0.0134545
HDAC1 histone deacetylase 1 -0.0134446
PCED1B PC-esterase domain containing 1B -0.0134388
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 -0.0134138
COX19 COX19 cytochrome c oxidase assembly factor -0.0133959
ANKIB1 ankyrin repeat and IBR domain containing 1 -0.0133895
H2AJ H2A.J histone -0.0133778
SSBP3 single stranded DNA binding protein 3 -0.0133731
EMB embigin -0.0133705
NCOR1 nuclear receptor corepressor 1 -0.0133385
KMT5B lysine methyltransferase 5B -0.0133216
RASAL2 RAS protein activator like 2 -0.0133189
RRM1 ribonucleotide reductase M1 -0.013305
ELL2 elongation factor, RNA polymerase II, 2 -0.0132981
TRRAP transformation/transcription domain-associated protein -0.013285
GSE1 Gse1 coiled-coil protein -0.0132837
PRKCSH protein kinase C substrate 80K-H -0.0132455
UBE3C ubiquitin protein ligase E3C -0.0132288
SIK3 SIK family kinase 3 -0.013222
ANKLE2 ankyrin repeat and LEM domain containing 2 -0.0132195
HDAC4 histone deacetylase 4 -0.0132163
LYPD3 LY6/PLAUR domain containing 3 -0.013172
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C -0.013169
SH3RF1 SH3 domain containing ring finger 1 -0.0131274
TACC3 transforming, acidic coiled-coil containing protein 3 -0.0131057
MAGT1 magnesium transporter 1 -0.0130983
NHSL1 NHS-like 1 -0.0130817
ISG15 ISG15 ubiquitin-like modifier -0.0130667
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -0.0130579
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -0.0130448
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 -0.0130423
IST1 increased sodium tolerance 1 homolog (yeast) -0.0130166
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa -0.013008
DTNA dystrobrevin, alpha -0.0129874
NUP214 nucleoporin 214kDa -0.0129533
STX8 syntaxin 8 -0.0129265
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -0.0129143
RPS20 ribosomal protein S20 -0.0128934
MYO9B myosin IXB -0.0128686
ABHD2 abhydrolase domain containing 2 -0.0128636
DOCK5 dedicator of cytokinesis 5 -0.0128402
FARSA phenylalanyl-tRNA synthetase, alpha subunit -0.0128333
PDLIM5 PDZ and LIM domain 5 -0.0128263
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -0.0128107
CCDC14 coiled-coil domain containing 14 -0.0127799
ARHGAP12 Rho GTPase activating protein 12 -0.012712
TIAM2 T-cell lymphoma invasion and metastasis 2 -0.0126983
ASCC1 activating signal cointegrator 1 complex subunit 1 -0.0126928
AKAP11 A kinase (PRKA) anchor protein 11 -0.012687
MEIS2 Meis homeobox 2 -0.0126774
CLINT1 clathrin interactor 1 -0.0126564
TNPO3 transportin 3 -0.0126341
HELZ2 helicase with zinc finger 2, transcriptional coactivator -0.0126071
FNBP1 formin binding protein 1 -0.0126057
KIF14 kinesin family member 14 -0.0125889
NUP205 nucleoporin 205kDa -0.0125889
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.0125823
NCOA6 nuclear receptor coactivator 6 -0.0125769
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.0125687
TUBA1B tubulin, alpha 1b -0.0125352
POU2F1 POU class 2 homeobox 1 -0.0124961
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) -0.0124822
MZT2B mitotic spindle organizing protein 2B -0.0123812
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -0.0123584
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha -0.012352
EHD1 EH-domain containing 1 -0.0123221
LMAN2L lectin, mannose-binding 2-like -0.0123194
MMS22L MMS22-like, DNA repair protein -0.0123155
JAK1 Janus kinase 1 -0.0123135
PCBD2 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 -0.0122931
STXBP5 syntaxin binding protein 5 (tomosyn) -0.0122413
C2CD2 C2 calcium-dependent domain containing 2 -0.0122093
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0121903
RAB14 RAB14, member RAS oncogene family -0.0121786
ANAPC16 anaphase promoting complex subunit 16 -0.0121695
WWOX WW domain containing oxidoreductase -0.0121677
SFXN1 sideroflexin 1 -0.0121677
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 -0.0121639
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 -0.0121545
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -0.0121545
NAP1L1 nucleosome assembly protein 1-like 1 -0.0121288
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) -0.0121128
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 -0.0120945
ZFYVE9 zinc finger, FYVE domain containing 9 -0.0120638
SHANK2 SH3 and multiple ankyrin repeat domains 2 -0.0120594
MELK maternal embryonic leucine zipper kinase -0.0120509
GPR137 G protein-coupled receptor 137 -0.0120188
METTL26 methyltransferase like 26 -0.0120096
COP1 COP1 E3 ubiquitin ligase -0.0119943
GPS1 G protein pathway suppressor 1 -0.0119819
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) -0.0119703
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -0.0119683
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -0.0119664
DNAH14 dynein, axonemal, heavy chain 14 -0.0119186
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase -0.0118825
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -0.0118762
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -0.0118467
SELENOS selenoprotein S -0.0118445
RNF168 ring finger protein 168, E3 ubiquitin protein ligase -0.0118301
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.0118235
ECI1 enoyl-CoA delta isomerase 1 -0.0118209
MACROH2A1 macroH2A.1 histone -0.0118133
NUCB1 nucleobindin 1 -0.0117929
RPS4X ribosomal protein S4, X-linked -0.0117774
AHCTF1 AT hook containing transcription factor 1 -0.0117494
PALB2 partner and localizer of BRCA2 -0.0117476
ZFAND6 zinc finger, AN1-type domain 6 -0.0117347
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 -0.0117306
TMED9 transmembrane emp24 protein transport domain containing 9 -0.0117276
ERICH1 glutamate-rich 1 -0.0117189
SNRPE small nuclear ribonucleoprotein polypeptide E -0.0117161
BLVRB biliverdin reductase B -0.0117111
IFNAR1 interferon (alpha, beta and omega) receptor 1 -0.0116938