MCF7_GSK-LSD1 2HCl_100nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description GSK-LSD1 2HCl 100nM perturbation in MCF7 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the MCF7_GSK-LSD1 2HCl_100nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
CTSD cathepsin D 0.182621
OVOL2 ovo-like zinc finger 2 0.160049
BCAS3 breast carcinoma amplified sequence 3 0.146478
TTC28 tetratricopeptide repeat domain 28 0.130244
IFI6 interferon, alpha-inducible protein 6 0.122024
HSPB1 heat shock 27kDa protein 1 0.096259
GPC6 glypican 6 0.0934653
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 0.0907235
PKM pyruvate kinase, muscle 0.0865999
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 0.0844116
KRT8 keratin 8, type II 0.0816123
NCOA3 nuclear receptor coactivator 3 0.0797761
HIP1 huntingtin interacting protein 1 0.0795783
FLNA filamin A, alpha 0.0710783
PTPRG protein tyrosine phosphatase, receptor type, G 0.0661083
ZMYND8 zinc finger, MYND-type containing 8 0.063939
PARD6B par-6 family cell polarity regulator beta 0.0637256
TFF1 trefoil factor 1 0.0622771
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0619101
RPS21 ribosomal protein S21 0.0610641
TPM4 tropomyosin 4 0.0599014
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 0.0595174
RABGAP1L RAB GTPase activating protein 1-like 0.0584974
MACROD2 MACRO domain containing 2 0.0577797
RPL37A ribosomal protein L37a 0.05668
S100A10 S100 calcium binding protein A10 0.0560447
USP32 ubiquitin specific peptidase 32 0.0551926
GRHL2 grainyhead-like 2 (Drosophila) 0.0551492
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 0.0546797
MSI2 musashi RNA-binding protein 2 0.0521384
PACS1 phosphofurin acidic cluster sorting protein 1 0.0505712
BCAS4 breast carcinoma amplified sequence 4 0.0505654
BSG basigin (Ok blood group) 0.0501572
PRRC2C proline-rich coiled-coil 2C 0.0498281
MYOF myoferlin 0.0478577
PARD3B par-3 family cell polarity regulator beta 0.046932
PHACTR4 phosphatase and actin regulator 4 0.0463443
SOS1 son of sevenless homolog 1 (Drosophila) 0.0463017
LY6E lymphocyte antigen 6 complex, locus E 0.0458248
ZRANB3 zinc finger, RAN-binding domain containing 3 0.0438436
AOPEP aminopeptidase O (putative) 0.0437306
PTPRK protein tyrosine phosphatase, receptor type, K 0.0429997
VMP1 vacuole membrane protein 1 0.0419444
NRIP1 nuclear receptor interacting protein 1 0.041316
LARP1 La ribonucleoprotein domain family, member 1 0.0410224
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0409535
LOC112694756 uncharaterized LOC112694756 0.0406534
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.0403196
AUTS2 autism susceptibility candidate 2 0.0398451
NBEA neurobeachin 0.0384555
CCND1 cyclin D1 0.0383061
RPL15 ribosomal protein L15 0.0378668
SOS2 son of sevenless homolog 2 (Drosophila) 0.037778
RC3H1 ring finger and CCCH-type domains 1 0.0376131
DIAPH2 diaphanous-related formin 2 0.0374624
UBE2H ubiquitin-conjugating enzyme E2H 0.0370787
XPR1 xenotropic and polytropic retrovirus receptor 1 0.0370499
DCDC2 doublecortin domain containing 2 0.0365327
PDPR pyruvate dehydrogenase phosphatase regulatory subunit 0.0360018
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.0345307
CD81 CD81 molecule 0.0343484
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0342127
GDNF glial cell derived neurotrophic factor 0.0341603
TTBK2 tau tubulin kinase 2 0.0336275
FCHSD2 FCH and double SH3 domains 2 0.0327656
TRIM37 tripartite motif containing 37 0.0327259
SLC38A1 solute carrier family 38, member 1 0.0326512
RAD51C RAD51 paralog C 0.0322831
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.0321261
UGDH UDP-glucose 6-dehydrogenase 0.0320884
LGALS3 lectin, galactoside-binding, soluble, 3 0.0319302
ACTN1 actinin, alpha 1 0.031455
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 0.0313773
MPHOSPH9 M-phase phosphoprotein 9 0.0312456
CXXC5 CXXC finger protein 5 0.0309194
SSH2 slingshot protein phosphatase 2 0.0308268
SGMS1 sphingomyelin synthase 1 0.0308006
SOGA1 suppressor of glucose, autophagy associated 1 0.0302463
MALRD1 MAM and LDL receptor class A domain containing 1 0.0302261
ANXA6 annexin A6 0.0301764
MYH9 myosin, heavy chain 9, non-muscle 0.0301182
CLTB clathrin, light chain B 0.0301043
LMBR1 limb development membrane protein 1 0.0300536
CLSTN2 calsyntenin 2 0.0299774
S100A11 S100 calcium binding protein A11 0.0298803
OSGIN2 oxidative stress induced growth inhibitor family member 2 0.0297059
PFN1 profilin 1 0.0295155
CALR calreticulin 0.0294138
FTH1 ferritin, heavy polypeptide 1 0.0284574
PAWR PRKC, apoptosis, WT1, regulator 0.0282726
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 0.0278549
SACS sacsin molecular chaperone 0.0275564
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 0.0273086
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.0272973
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.0272714
RPS15A ribosomal protein S15a 0.0271822
JPT1 Jupiter microtubule associated homolog 1 0.0266656
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.0265346
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.0264346
PGM2L1 phosphoglucomutase 2-like 1 0.0261846
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0261064
CERS2 ceramide synthase 2 0.0259922
NRG3 neuregulin 3 0.0259745
MRPL13 mitochondrial ribosomal protein L13 0.0259305
CEP112 centrosomal protein 112kDa 0.0259129
RAB11FIP3 RAB11 family interacting protein 3 (class II) 0.0256861
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.025682
RHPN2 rhophilin, Rho GTPase binding protein 2 0.0256181
CBX5 chromobox homolog 5 0.0254155
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 0.0254102
CPA6 carboxypeptidase A6 0.0253977
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.0253341
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0252657
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.0251764
STC2 stanniocalcin 2 0.0247973
KIAA0319L KIAA0319-like 0.0246333
PTPRF protein tyrosine phosphatase, receptor type, F 0.0245394
HRNR hornerin 0.0244321
KRT19 keratin 19, type I 0.02427
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.0241716
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa 0.0240558
RAD23B RAD23 homolog B (S. cerevisiae) 0.023965
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.0233092
CDYL2 chromodomain protein, Y-like 2 0.0228749
ZCCHC7 zinc finger, CCHC domain containing 7 0.022834
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.0227715
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.022688
ECE1 endothelin converting enzyme 1 0.0226845
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.0226076
ENO1 enolase 1, (alpha) 0.0223909
CEP170 centrosomal protein 170kDa 0.022358
QRICH1 glutamine-rich 1 0.0223466
CSDE1 cold shock domain containing E1, RNA-binding 0.0222711
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 0.0220675
DSTN destrin (actin depolymerizing factor) 0.0217941
EEIG1 estrogen-induced osteoclastogenesis regulator 1 0.0217845
SEC23A Sec23 homolog A (S. cerevisiae) 0.0217711
CUTA cutA divalent cation tolerance homolog (E. coli) 0.0217663
POGZ pogo transposable element with ZNF domain 0.0216587
DOCK5 dedicator of cytokinesis 5 0.0215779
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 0.0215066
TESK2 testis-specific kinase 2 0.0215061
MUC1 mucin 1, cell surface associated 0.0214747
MAML3 mastermind-like 3 (Drosophila) 0.021449
ELOVL2 ELOVL fatty acid elongase 2 0.0214383
VASP vasodilator-stimulated phosphoprotein 0.0211412
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.0211369
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.0211122
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.0210643
SMIM14 small integral membrane protein 14 0.0210265
FAM13B family with sequence similarity 13, member B 0.0210043
DHCR7 7-dehydrocholesterol reductase 0.0209842
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.0209736
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0209664
RPN2 ribophorin II 0.0208605
UBE2R2 ubiquitin-conjugating enzyme E2R 2 0.020801
MYO9B myosin IXB 0.0207783
KLHL23 kelch-like family member 23 0.0207637
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.0207598
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0207401
HDAC8 histone deacetylase 8 0.0207153
ULK1 unc-51 like autophagy activating kinase 1 0.0206371
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0206279
SQLE squalene epoxidase 0.0205631
TANGO6 transport and golgi organization 6 homolog (Drosophila) 0.0203141
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) 0.0202853
DDB2 damage-specific DNA binding protein 2, 48kDa 0.0202315
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.0202306
PFDN4 prefoldin subunit 4 0.0201786
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.0201556
GOLGB1 golgin B1 0.020123
TRIM56 tripartite motif containing 56 0.0199999
BRCA2 breast cancer 2, early onset 0.0198924
STXBP1 syntaxin binding protein 1 0.019854
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0197956
R3HDM1 R3H domain containing 1 0.0197758
PPP1R13B protein phosphatase 1, regulatory subunit 13B 0.019751
IFI27 interferon, alpha-inducible protein 27 0.0197462
CD47 CD47 molecule 0.0197233
TUBB tubulin, beta class I 0.0196885
ERCC1 excision repair cross-complementation group 1 0.0196055
ELOVL5 ELOVL fatty acid elongase 5 0.0195782
PGCKA1 PDCD10 and GCKIII kinases associated 1 0.0195742
YIPF4 Yip1 domain family, member 4 0.01942
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.0193954
ELP2 elongator acetyltransferase complex subunit 2 0.0193646
OGA O-GlcNAcase 0.0193176
PRRC2A proline-rich coiled-coil 2A 0.0193132
ZHX2 zinc fingers and homeoboxes 2 0.0192989
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 0.0192286
RNF213 ring finger protein 213 0.0191721
GATAD2B GATA zinc finger domain containing 2B 0.0191299
ZNF609 zinc finger protein 609 0.0191247
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.0191055
FAM234A family with sequence similarity 234 member A 0.019052
SDK2 sidekick cell adhesion molecule 2 0.0189875
USP15 ubiquitin specific peptidase 15 0.0189872
RPL30 ribosomal protein L30 0.0188474
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0188322
COL5A1 collagen, type V, alpha 1 0.0187892
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.018769
KIF13A kinesin family member 13A 0.0187234
TCF12 transcription factor 12 0.0187196
TMEM135 transmembrane protein 135 0.0187042
POTEF POTE ankyrin domain family, member F 0.0186139
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.0184948
PLIN3 perilipin 3 0.0184898
CANT1 calcium activated nucleotidase 1 0.0184894
PALLD palladin, cytoskeletal associated protein 0.0184738
CERS4 ceramide synthase 4 0.0184021
PRKCSH protein kinase C substrate 80K-H 0.0182827
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.018274
SKA2 spindle and kinetochore associated complex subunit 2 0.0181997
MTSS1 metastasis suppressor 1 0.0181657
IL27RA interleukin 27 receptor, alpha 0.0181605
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor 0.0180687
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0180412
TTC7B tetratricopeptide repeat domain 7B 0.0180166
ARL15 ADP-ribosylation factor-like 15 0.0180138
CCDC91 coiled-coil domain containing 91 0.0179808
MAVS mitochondrial antiviral signaling protein 0.0179428
UBL4A ubiquitin-like 4A 0.0178891
ERMP1 endoplasmic reticulum metallopeptidase 1 0.017786
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.0177586
PARP4 poly (ADP-ribose) polymerase family, member 4 0.0177224
N4BP3 NEDD4 binding protein 3 0.0176948
IL6ST interleukin 6 signal transducer 0.0176541
C1QBP complement component 1, q subcomponent binding protein 0.0176365
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 0.0175667
PHIP pleckstrin homology domain interacting protein 0.017483
SIAH2 siah E3 ubiquitin protein ligase 2 0.017479
HNRNPF heterogeneous nuclear ribonucleoprotein F 0.017458
ATAD2B ATPase family, AAA domain containing 2B 0.0173807
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0173745
SYNGR2 synaptogyrin 2 0.0173571
AFF1 AF4/FMR2 family, member 1 0.0172833
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.0172515
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 0.0171942
ATP5MC2 ATP synthase membrane subunit c locus 2 0.0171804
SEPTIN6 septin 6 0.0171742
TOR1A torsin family 1, member A (torsin A) 0.0171589
B2M beta-2-microglobulin 0.0171465
IGFBP4 insulin-like growth factor binding protein 4 0.0171368
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0170764
ADIPOR2 adiponectin receptor 2 0.0170755
GREB1L growth regulation by estrogen in breast cancer-like 0.0170714
RUSC2 RUN and SH3 domain containing 2 0.0169708
DEGS1 delta(4)-desaturase, sphingolipid 1 0.0169445
ERBB4 erb-b2 receptor tyrosine kinase 4 0.0169371
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 0.0169063
WDR26 WD repeat domain 26 0.016841
INVS inversin 0.01676
MSH3 mutS homolog 3 0.0167593
PARP14 poly (ADP-ribose) polymerase family, member 14 0.0167516
VCL vinculin 0.0166972
KTN1 kinectin 1 (kinesin receptor) 0.0166874
AMZ1 archaelysin family metallopeptidase 1 0.0166652
ASCC1 activating signal cointegrator 1 complex subunit 1 0.0166403
GPRC5C G protein-coupled receptor, class C, group 5, member C 0.0166355
FNDC3A fibronectin type III domain containing 3A 0.0166264
PAN3 PAN3 poly(A) specific ribonuclease subunit 0.0166181
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.0165989
NFIB nuclear factor I/B 0.0165842
MAST4 microtubule associated serine/threonine kinase family member 4 0.0165779
DNAAF9 dynein axonemal assembly factor 9 0.0165697
CENPF centromere protein F, 350/400kDa 0.0165585
AFF4 AF4/FMR2 family, member 4 0.01652
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 0.0165131
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0165063
BCL2L1 BCL2-like 1 0.0164984
TNPO3 transportin 3 0.0164879
IGSF3 immunoglobulin superfamily, member 3 0.0164782
CANX calnexin 0.0164628
ADAR adenosine deaminase, RNA-specific 0.01646
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.0164103
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) 0.0163591
LRRC58 leucine rich repeat containing 58 0.016337
MXD4 MAX dimerization protein 4 0.0162817
FLOT1 flotillin 1 0.0162287
POLK polymerase (DNA directed) kappa 0.0162188
AP2A2 adaptor-related protein complex 2, alpha 2 subunit 0.0162059
SBNO1 strawberry notch homolog 1 (Drosophila) 0.0161622
UNK unkempt family zinc finger 0.0161577
TM9SF3 transmembrane 9 superfamily member 3 0.0161564
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.016139
KDM6A lysine (K)-specific demethylase 6A 0.016116
H1-10 H1.10 linker histone 0.0160956
RNFT1 ring finger protein, transmembrane 1 0.0160415
ADPGK ADP-dependent glucokinase 0.0159506
TRAFD1 TRAF-type zinc finger domain containing 1 0.0159403
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 0.0158972
PDZRN3 PDZ domain containing ring finger 3 0.015867
H2AZ1 H2A.Z variant histone 1 0.0158551
CAPN8 calpain 8 0.0158367
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0157876
CD63 CD63 molecule 0.0157514
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) 0.0157342
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.0157276
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.0157119
H2AC6 H2A clustered histone 6 0.0156606
PDS5A PDS5 cohesin associated factor A 0.0156502
IFT140 intraflagellar transport 140 0.0155778
DLC1 DLC1 Rho GTPase activating protein 0.015475
STMN1 stathmin 1 0.0154564
LRP1B low density lipoprotein receptor-related protein 1B 0.0153869
AURKA aurora kinase A 0.0153752
OLA1 Obg-like ATPase 1 0.0153744
ZNFX1 zinc finger, NFX1-type containing 1 0.0153599
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0153375
SLC35D4 solute carrier family 35 member D4 0.0153325
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0153278
TMEM184C transmembrane protein 184C 0.0152582
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.0152557
VEZF1 vascular endothelial zinc finger 1 0.015248
DSG2 desmoglein 2 0.0152041
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 0.0151873
RHOBTB3 Rho-related BTB domain containing 3 0.015179
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 0.01516
XPC xeroderma pigmentosum, complementation group C 0.0151476
NXNL2 nucleoredoxin-like 2 0.015117
NECTIN1 nectin cell adhesion molecule 1 0.0151072
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0150905
RHEB Ras homolog enriched in brain 0.0150651
RPS5 ribosomal protein S5 0.0150496
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.0150371
LITAF lipopolysaccharide-induced TNF factor 0.0149662
SCCPDH saccharopine dehydrogenase (putative) 0.014929
IDI1 isopentenyl-diphosphate delta isomerase 1 0.014883
FHIT fragile histidine triad 0.0148541
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.0148475
RPL31 ribosomal protein L31 0.0147993
TBCK TBC1 domain containing kinase 0.0147887
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.0147761
CHDH choline dehydrogenase 0.0147375
NEO1 neogenin 1 0.0147187
TRIM25 tripartite motif containing 25 0.0147158
USP53 ubiquitin specific peptidase 53 0.0147147
NALF1 NALCN channel auxiliary factor 1 0.0147075
CDC27 cell division cycle 27 0.014695
FGF12 fibroblast growth factor 12 0.0146699
ZYX zyxin 0.0146617
RB1 retinoblastoma 1 0.014657
HIBCH 3-hydroxyisobutyryl-CoA hydrolase 0.0146201
KIAA0232 KIAA0232 0.0146201
GAPVD1 GTPase activating protein and VPS9 domains 1 0.014607
SUCLG1 succinate-CoA ligase, alpha subunit 0.0146032
CDV3 CDV3 homolog (mouse) 0.0146031
IRAK1 interleukin-1 receptor-associated kinase 1 0.014594
ZEB1 zinc finger E-box binding homeobox 1 0.0145617
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.0145565
RPS9 ribosomal protein S9 0.0145506
KYAT1 kynurenine aminotransferase 1 0.014527
GSN gelsolin 0.0145117
FAF2 Fas associated factor family member 2 0.0144917
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0144742
KAT7 K(lysine) acetyltransferase 7 0.0144731
INTS6 integrator complex subunit 6 0.0144664
UBTD2 ubiquitin domain containing 2 0.0144622
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like 0.0144276
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.0144247
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 0.014375
AHNAK2 AHNAK nucleoprotein 2 0.0143143
CMSS1 cms1 ribosomal small subunit homolog (yeast) 0.0142467
BRD8 bromodomain containing 8 0.0142268
DPY19L1 dpy-19-like 1 (C. elegans) 0.0142237
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.0141687
SKIL SKI-like proto-oncogene 0.0141293
SNED1 sushi, nidogen and EGF-like domains 1 0.0141112
SOAT1 sterol O-acyltransferase 1 0.0141065
CCDC142 coiled-coil domain containing 142 0.0140876
KRT80 keratin 80, type II 0.0140364
PLCG1 phospholipase C, gamma 1 0.0140208
DENND1A DENN/MADD domain containing 1A 0.0140153
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0140129
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.0139924
QSOX1 quiescin Q6 sulfhydryl oxidase 1 0.0139907
ERBB3 erb-b2 receptor tyrosine kinase 3 0.0139601
FRYL FRY-like 0.0139417
CDH18 cadherin 18, type 2 0.0139246
WEE1 WEE1 G2 checkpoint kinase 0.0139235
SLC38A10 solute carrier family 38, member 10 0.0138745
IQGAP1 IQ motif containing GTPase activating protein 1 0.0138559
ZNF652 zinc finger protein 652 0.0138294
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.013819
RPL7A ribosomal protein L7a 0.0137843
RABGAP1 RAB GTPase activating protein 1 0.0137833
RAD54L2 RAD54-like 2 (S. cerevisiae) 0.0137463
RRP1B ribosomal RNA processing 1B 0.013745
CUEDC1 CUE domain containing 1 0.0137433
LPCAT3 lysophosphatidylcholine acyltransferase 3 0.0137388
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 0.0137386
CLU clusterin 0.0137292
SOD1 superoxide dismutase 1, soluble 0.0137021
ARF4 ADP-ribosylation factor 4 0.0137003
SLC30A9 solute carrier family 30 (zinc transporter), member 9 0.0136987
MUC16 mucin 16, cell surface associated 0.0136862
PER2 period circadian clock 2 0.0136621
GRID1 glutamate receptor, ionotropic, delta 1 0.0136248
ANXA7 annexin A7 0.0136192
AK1 adenylate kinase 1 0.0135981
HAGH hydroxyacylglutathione hydrolase 0.0135969
PDIA4 protein disulfide isomerase family A, member 4 0.0135783
ICMT isoprenylcysteine carboxyl methyltransferase 0.0135597
ATG9A autophagy related 9A 0.013553
GAB2 GRB2-associated binding protein 2 0.0135478
DIDO1 death inducer-obliterator 1 0.0135099
RIPOR3 RIPOR family member 3 0.0135027
SLC39A1 solute carrier family 39 (zinc transporter), member 1 0.0134869
BCAP31 B-cell receptor-associated protein 31 0.0134538
HOMER2 homer scaffolding protein 2 0.0134479
FLOT2 flotillin 2 0.0134375
FBXL5 F-box and leucine-rich repeat protein 5 0.0133998
PCSK6 proprotein convertase subtilisin/kexin type 6 0.0133882
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing 0.0133719
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.0133687
SMC3 structural maintenance of chromosomes 3 0.0133674
FDPS farnesyl diphosphate synthase 0.0133653
AHI1 Abelson helper integration site 1 0.0133381
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 0.0133192
NINL ninein-like 0.0133083
EXTL3 exostosin-like glycosyltransferase 3 0.0132774
TMEM65 transmembrane protein 65 0.0132226
CSRP1 cysteine and glycine-rich protein 1 0.0132148
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.013208
THEM4 thioesterase superfamily member 4 0.0131666
OXA1L oxidase (cytochrome c) assembly 1-like 0.0131637
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.0131423
OSBPL10 oxysterol binding protein-like 10 0.0131196
TMED3 transmembrane emp24 protein transport domain containing 3 0.0131113
PNPLA8 patatin-like phospholipase domain containing 8 0.0130631
SESTD1 SEC14 and spectrin domains 1 0.0130631
MAP7D3 MAP7 domain containing 3 0.0130576
YLPM1 YLP motif containing 1 0.0130456
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.0130247
DTWD1 DTW domain containing 1 0.0129701
GIPC1 GIPC PDZ domain containing family, member 1 0.0129622
SYT12 synaptotagmin XII 0.0129258
RPS4X ribosomal protein S4, X-linked 0.0128869
TAPBP TAP binding protein (tapasin) 0.0128803
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 0.0128732
MCRIP2 MAPK regulated corepressor interacting protein 2 0.0128689
RAB21 RAB21, member RAS oncogene family 0.0128615
STX5 syntaxin 5 0.0128417
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.0128337
SLC44A2 solute carrier family 44 (choline transporter), member 2 0.0128299
MAP2K1 mitogen-activated protein kinase kinase 1 0.0128216
PRNP prion protein 0.0128171
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 0.0128155
CSTB cystatin B (stefin B) 0.0128046
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) 0.0127951
COXFA4 cytochrome c oxidase associated subunit FA4 0.012766
ZMYM4 zinc finger, MYM-type 4 0.0127638
IGSF1 immunoglobulin superfamily, member 1 0.0127502
PTRH2 peptidyl-tRNA hydrolase 2 0.0127129
NADK2 NAD kinase 2, mitochondrial 0.0126937
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.0126747
NPNT nephronectin 0.0126473
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.0126221
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 0.0125719
KDM4B lysine (K)-specific demethylase 4B 0.0125681
FBP1 fructose-1,6-bisphosphatase 1 0.0125595
MAN1B1 mannosidase, alpha, class 1B, member 1 0.012545
DUT deoxyuridine triphosphatase 0.0125375
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0125229
TMEM131 transmembrane protein 131 0.0125205
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.0125149
ASS1 argininosuccinate synthase 1 0.0125079
RASGEF1B RasGEF domain family, member 1B 0.0124854
LRMDA leucine rich melanocyte differentiation associated 0.0124486
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0124459
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.0124422
SEC62 SEC62 homolog (S. cerevisiae) 0.0124272
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum) 0.0124267
MIA3 melanoma inhibitory activity family, member 3 0.0124189
KRI1 KRI1 homolog (S. cerevisiae) 0.0124161
SPRED2 sprouty-related, EVH1 domain containing 2 0.0124138
BASP1 brain abundant, membrane attached signal protein 1 0.0123908
EPHA6 EPH receptor A6 0.0123897
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.0123857
NCAPG2 non-SMC condensin II complex, subunit G2 0.0123848
IRF3 interferon regulatory factor 3 0.0123828
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 0.0123689
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 0.0123607
LGALS12 lectin, galactoside-binding, soluble, 12 0.0123348
STX12 syntaxin 12 0.0123206
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 0.012315
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 0.0122638
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.0122584
GTF2I general transcription factor IIi 0.0122434
EML5 echinoderm microtubule associated protein like 5 0.0122431
AGO4 argonaute RISC catalytic component 4 0.0122145
SLC35B1 solute carrier family 35, member B1 0.0122019
PHLDB1 pleckstrin homology-like domain, family B, member 1 0.0121713
NBDY negative regulator of P-body association 0.0121685
TP53 tumor protein p53 0.0121339
PDGFA platelet-derived growth factor alpha polypeptide 0.0121236
HOMER1 homer scaffolding protein 1 0.0121132
ZNF592 zinc finger protein 592 0.012108
LMAN1 lectin, mannose-binding, 1 0.0120712
WASHC2C WASH complex subunit 2C 0.0120711

decreased expression

Symbol Name Standardized Value
SYTL2 synaptotagmin-like 2 -0.165383
EVL Enah/Vasp-like -0.162108
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.140279
IGF1R insulin-like growth factor 1 receptor -0.124454
DSCAM Down syndrome cell adhesion molecule -0.105245
SDK1 sidekick cell adhesion molecule 1 -0.0824311
NRCAM neuronal cell adhesion molecule -0.0712832
CALCR calcitonin receptor -0.0705843
DTNA dystrobrevin, alpha -0.0651025
BPTF bromodomain PHD finger transcription factor -0.0627295
WWOX WW domain containing oxidoreductase -0.0619846
ESR1 estrogen receptor 1 -0.0607854
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0593792
KYNU kynureninase -0.0591912
MBD5 methyl-CpG binding domain protein 5 -0.0571617
PARD3 par-3 family cell polarity regulator -0.0534654
AGR2 anterior gradient 2 -0.0504408
PRKCE protein kinase C, epsilon -0.0503448
DSPP dentin sialophosphoprotein -0.0502572
ZFAND3 zinc finger, AN1-type domain 3 -0.049989
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -0.0486215
USP34 ubiquitin specific peptidase 34 -0.0482704
ITPRID2 ITPR interacting domain containing 2 -0.0474749
CUX1 cut-like homeobox 1 -0.0465175
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0436812
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) -0.0436359
AREG amphiregulin -0.0426289
TRIM33 tripartite motif containing 33 -0.0425095
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 -0.0420762
PBX3 pre-B-cell leukemia homeobox 3 -0.0409133
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 -0.0408896
FOXP1 forkhead box P1 -0.040865
SIPA1L1 signal-induced proliferation-associated 1 like 1 -0.040821
PBX1 pre-B-cell leukemia homeobox 1 -0.0401305
RPS6 ribosomal protein S6 -0.0398436
GFRA1 GDNF family receptor alpha 1 -0.0398057
RPL6 ribosomal protein L6 -0.0394359
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase -0.0383219
GREB1 growth regulation by estrogen in breast cancer 1 -0.0373659
PCDH7 protocadherin 7 -0.037298
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.0369531
MED13L mediator complex subunit 13-like -0.0368103
MACF1 microtubule-actin crosslinking factor 1 -0.0365438
DLG1 discs, large homolog 1 (Drosophila) -0.0362769
GPHN gephyrin -0.0362501
CCSER1 coiled-coil serine-rich protein 1 -0.0362492
RPS8 ribosomal protein S8 -0.0356923
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0352806
RAD51B RAD51 paralog B -0.0350652
RPLP1 ribosomal protein, large, P1 -0.0348458
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.0346557
THOC2 THO complex 2 -0.0344815
NCOA2 nuclear receptor coactivator 2 -0.0344753
NUMB numb homolog (Drosophila) -0.0342959
TIAM1 T-cell lymphoma invasion and metastasis 1 -0.0341801
TTLL10 tubulin tyrosine ligase-like family member 10 -0.0341651
KPNB1 karyopherin (importin) beta 1 -0.0341143
JARID2 jumonji, AT rich interactive domain 2 -0.0336667
RPS19 ribosomal protein S19 -0.0336189
CREBBP CREB binding protein -0.0334423
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -0.0332621
KRT18 keratin 18, type I -0.0331705
ATXN1 ataxin 1 -0.0325862
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.032516
WWP1 WW domain containing E3 ubiquitin protein ligase 1 -0.0324152
STK24 serine/threonine kinase 24 -0.03192
UBE2E2 ubiquitin-conjugating enzyme E2E 2 -0.0318817
PRRC2B proline-rich coiled-coil 2B -0.0316913
ZFHX3 zinc finger homeobox 3 -0.0316118
DOCK1 dedicator of cytokinesis 1 -0.0311063
GNA14 guanine nucleotide binding protein (G protein), alpha 14 -0.031014
SMC4 structural maintenance of chromosomes 4 -0.0309367
FAF1 Fas (TNFRSF6) associated factor 1 -0.0305828
DICER1 dicer 1, ribonuclease type III -0.030317
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.0301665
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein -0.0300459
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.0300112
ATP9A ATPase, class II, type 9A -0.0298993
TUBD1 tubulin, delta 1 -0.0298288
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -0.0297017
CENPP centromere protein P -0.0295819
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0295116
DLG5 discs, large homolog 5 (Drosophila) -0.0294377
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 -0.0294042
NPEPPS aminopeptidase puromycin sensitive -0.0291754
TMEM150C transmembrane protein 150C -0.0288607
ACSL3 acyl-CoA synthetase long-chain family member 3 -0.0285425
SULF2 sulfatase 2 -0.0282629
XPO1 exportin 1 -0.0282478
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0280954
SEPTIN9 septin 9 -0.0278473
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0277279
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) -0.0275028
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -0.0273109
CTNND2 catenin (cadherin-associated protein), delta 2 -0.0271485
GAN gigaxonin -0.0270745
STX8 syntaxin 8 -0.0269895
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.0266142
PTGES2 prostaglandin E synthase 2 -0.0265869
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.026544
TOP6BL TOP6B like initiator of meiotic double strand breaks -0.0264564
MLPH melanophilin -0.026347
FANCI Fanconi anemia, complementation group I -0.0260736
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) -0.0260349
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 -0.0255045
RNF216 ring finger protein 216 -0.0254345
GPATCH8 G patch domain containing 8 -0.0254111
MDN1 MDN1, midasin homolog (yeast) -0.0252216
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.0251111
MTDH metadherin -0.0248109
SND1 staphylococcal nuclease and tudor domain containing 1 -0.0247152
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0244983
ARHGAP12 Rho GTPase activating protein 12 -0.024303
CDC42SE2 CDC42 small effector 2 -0.0240011
EIF5B eukaryotic translation initiation factor 5B -0.0239985
AP1M2 adaptor-related protein complex 1, mu 2 subunit -0.0239637
KMT2E lysine (K)-specific methyltransferase 2E -0.0237347
TUFM Tu translation elongation factor, mitochondrial -0.023639
RPS2 ribosomal protein S2 -0.0235841
GATAD2A GATA zinc finger domain containing 2A -0.0232959
CAPZB capping protein (actin filament) muscle Z-line, beta -0.0232184
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -0.0231835
JUP junction plakoglobin -0.0231746
NRP1 neuropilin 1 -0.0231692
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0229849
NF1 neurofibromin 1 -0.0228341
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0227368
KAT6B K(lysine) acetyltransferase 6B -0.0226228
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B -0.0223626
TMEM64 transmembrane protein 64 -0.0222733
RPL35 ribosomal protein L35 -0.0221977
ATXN7L1 ataxin 7-like 1 -0.0221952
CKAP5 cytoskeleton associated protein 5 -0.0220726
EMCN endomucin -0.0220686
DPH6 diphthamine biosynthesis 6 -0.0220083
AKAP9 A kinase (PRKA) anchor protein 9 -0.0218824
RORA RAR-related orphan receptor A -0.021871
BAZ1B bromodomain adjacent to zinc finger domain, 1B -0.0217212
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.02165
APLP2 amyloid beta (A4) precursor-like protein 2 -0.0214991
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -0.0214836
TSC22D2 TSC22 domain family, member 2 -0.0214777
RSF1 remodeling and spacing factor 1 -0.0214577
TRIO trio Rho guanine nucleotide exchange factor -0.021446
C1ORF21 chromosome 1 open reading frame 21 -0.0213685
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.0213336
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 -0.0212251
ZFP36L2 ZFP36 ring finger protein-like 2 -0.0211637
FANCA Fanconi anemia, complementation group A -0.0211096
AGO3 argonaute RISC catalytic component 3 -0.0210677
NLN neurolysin (metallopeptidase M3 family) -0.0210677
BTBD7 BTB (POZ) domain containing 7 -0.0210373
SMYD3 SET and MYND domain containing 3 -0.0209987
EIF4B eukaryotic translation initiation factor 4B -0.0209258
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.0207575
KNL1 kinetochore scaffold 1 -0.0206751
PPP6R2 protein phosphatase 6, regulatory subunit 2 -0.0204826
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.0204784
GOLGA2 golgin A2 -0.0204571
COMMD10 COMM domain containing 10 -0.0204549
GNA12 guanine nucleotide binding protein (G protein) alpha 12 -0.0204406
RPS17 ribosomal protein S17 -0.0203937
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.0203651
MED13 mediator complex subunit 13 -0.0203246
WAC WW domain containing adaptor with coiled-coil -0.0203217
TMPO thymopoietin -0.0202882
PDIA6 protein disulfide isomerase family A, member 6 -0.020287
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -0.0202848
GDI2 GDP dissociation inhibitor 2 -0.0202133
CNKSR3 CNKSR family member 3 -0.0201674
DDHD1 DDHD domain containing 1 -0.0201645
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.0201069
BCL2 B-cell CLL/lymphoma 2 -0.0201002
PA2G4 proliferation-associated 2G4, 38kDa -0.0200936
RAB6A RAB6A, member RAS oncogene family -0.0200815
USP6NL USP6 N-terminal like -0.020051
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -0.0200499
KDM2A lysine (K)-specific demethylase 2A -0.020047
CFAP44 cilia and flagella associated protein 44 -0.0199625
MYO5C myosin VC -0.0199412
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0199405
CA12 carbonic anhydrase XII -0.0196496
MAP7 microtubule-associated protein 7 -0.0196185
ZBTB7A zinc finger and BTB domain containing 7A -0.0195902
GABPB2 GA binding protein transcription factor, beta subunit 2 -0.0195448
NRDC nardilysin convertase -0.0195223
SCMH1 sex comb on midleg homolog 1 (Drosophila) -0.0194907
KIAA1217 KIAA1217 -0.0194294
CDYL chromodomain protein, Y-like -0.0194186
SIDT1 SID1 transmembrane family, member 1 -0.0194165
RERE arginine-glutamic acid dipeptide (RE) repeats -0.0193958
TRPS1 trichorhinophalangeal syndrome I -0.019374
FAM168B family with sequence similarity 168, member B -0.0193736
EHBP1 EH domain binding protein 1 -0.0193657
CLTA clathrin, light chain A -0.0193594
SRPK2 SRSF protein kinase 2 -0.0193401
PATJ PATJ crumbs cell polarity complex component -0.0193073
MAP3K20 mitogen-activated protein kinase kinase kinase 20 -0.0192325
JAK1 Janus kinase 1 -0.0191867
TBC1D5 TBC1 domain family, member 5 -0.0191742
LRIF1 ligand dependent nuclear receptor interacting factor 1 -0.0190874
MAP4 microtubule-associated protein 4 -0.0190722
EPHA4 EPH receptor A4 -0.0190405
MCU mitochondrial calcium uniporter -0.0190392
GALC galactosylceramidase -0.0189536
UTRN utrophin -0.0189311
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.018924
HDLBP high density lipoprotein binding protein -0.0188492
CAMK1D calcium/calmodulin-dependent protein kinase ID -0.018776
CORO1B coronin, actin binding protein, 1B -0.0186665
H3-3B H3.3 histone B -0.0186224
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 -0.0185953
PDE7A phosphodiesterase 7A -0.0185551
METTL2A methyltransferase like 2A -0.0185484
HEATR6 HEAT repeat containing 6 -0.018523
UBE4A ubiquitination factor E4A -0.0184494
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0184399
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -0.0184168
ANAPC5 anaphase promoting complex subunit 5 -0.0183745
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -0.0183527
TMEM120B transmembrane protein 120B -0.0183403
SAMD12 sterile alpha motif domain containing 12 -0.0183214
KIF21A kinesin family member 21A -0.0182818
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.0182764
KDM3B lysine (K)-specific demethylase 3B -0.0182686
TPX2 TPX2, microtubule-associated -0.0182543
ACYP2 acylphosphatase 2, muscle type -0.0182392
OSBPL9 oxysterol binding protein-like 9 -0.018199
SIN3A SIN3 transcription regulator family member A -0.0181507
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0179864
HEATR5B HEAT repeat containing 5B -0.0178917
IWS1 IWS1 homolog (S. cerevisiae) -0.0178846
TTF2 transcription termination factor, RNA polymerase II -0.0178682
SASH1 SAM and SH3 domain containing 1 -0.0178204
SHANK2 SH3 and multiple ankyrin repeat domains 2 -0.0176887
SLX4IP SLX4 interacting protein -0.0176887
LARP4B La ribonucleoprotein domain family, member 4B -0.0175136
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.0174202
PNISR PNN-interacting serine/arginine-rich protein -0.0174046
SF3B1 splicing factor 3b, subunit 1, 155kDa -0.0173598
TOP1 topoisomerase (DNA) I -0.0173584
TPD52L1 tumor protein D52-like 1 -0.0173346
AHNAK AHNAK nucleoprotein -0.0173292
NRBP1 nuclear receptor binding protein 1 -0.0173156
SUMF1 sulfatase modifying factor 1 -0.0172847
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -0.0172114
SETD5 SET domain containing 5 -0.0172025
SFSWAP splicing factor, suppressor of white-apricot family -0.0171997
EEA1 early endosome antigen 1 -0.0171917
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.0171452
PTPN11 protein tyrosine phosphatase, non-receptor type 11 -0.0171145
CAV1 caveolin 1, caveolae protein, 22kDa -0.017032
TASOR2 transcription activation suppressor family member 2 -0.0170152
PLK2 polo-like kinase 2 -0.0169818
RTF2 replication termination factor 2 -0.0169213
LCOR ligand dependent nuclear receptor corepressor -0.0168127
ZNF148 zinc finger protein 148 -0.0167616
C6ORF141 chromosome 6 open reading frame 141 -0.016756
NCOR2 nuclear receptor corepressor 2 -0.0167469
CHLSN cholesin -0.0167246
EPB41L5 erythrocyte membrane protein band 4.1 like 5 -0.0167235
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -0.016708
PDE8A phosphodiesterase 8A -0.0167013
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.0166962
NSD3 nuclear receptor binding SET domain protein 3 -0.0166509
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.016643
ZSWIM5 zinc finger, SWIM-type containing 5 -0.0166242
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -0.0165671
MECOM MDS1 and EVI1 complex locus -0.0164944
EXOC2 exocyst complex component 2 -0.0164806
SHISA9 shisa family member 9 -0.0164757
NIPAL2 NIPA-like domain containing 2 -0.016471
RNGTT RNA guanylyltransferase and 5'-phosphatase -0.0164595
GON4L gon-4-like (C. elegans) -0.0164464
ADNP activity-dependent neuroprotector homeobox -0.0164453
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0164081
ITCH itchy E3 ubiquitin protein ligase -0.0164038
ZFR zinc finger RNA binding protein -0.0163889
MGA MGA, MAX dimerization protein -0.0163886
FKBP5 FK506 binding protein 5 -0.0163696
MYO1B myosin IB -0.0163266
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.0162468
RPTOR regulatory associated protein of MTOR, complex 1 -0.0162334
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) -0.0162108
SIPA1L2 signal-induced proliferation-associated 1 like 2 -0.0161907
CHD4 chromodomain helicase DNA binding protein 4 -0.0161628
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.0161445
RCOR1 REST corepressor 1 -0.0161299
PHB1 prohibitin 1 -0.016121
ZFAND6 zinc finger, AN1-type domain 6 -0.016107
SNX5 sorting nexin 5 -0.0160185
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0160175
SPIDR scaffolding protein involved in DNA repair -0.0160022
MICU2 mitochondrial calcium uptake 2 -0.0159952
ITSN2 intersectin 2 -0.0159913
SFMBT2 Scm-like with four mbt domains 2 -0.0159644
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 -0.0159534
GNAS GNAS complex locus -0.015941
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -0.0159092
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0158617
NT5C3A 5'-nucleotidase, cytosolic IIIA -0.0158339
KCNK6 potassium channel, two pore domain subfamily K, member 6 -0.0157548
EEIG2 EEIG family member 2 -0.015754
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 -0.0157503
STAG2 stromal antigen 2 -0.0157065
UBE2G1 ubiquitin-conjugating enzyme E2G 1 -0.0156582
QSER1 glutamine and serine rich 1 -0.0156519
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 -0.0156246
RPAP2 RNA polymerase II associated protein 2 -0.0155987
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -0.0155701
TOP2B topoisomerase (DNA) II beta 180kDa -0.0155666
SENP5 SUMO1/sentrin specific peptidase 5 -0.0155529
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0155472
TBCA tubulin folding cofactor A -0.0155132
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0154596
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -0.0154018
NVL nuclear VCP-like -0.0153921
MAP2K4 mitogen-activated protein kinase kinase 4 -0.0153745
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 -0.0153544
RPL28 ribosomal protein L28 -0.015343
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.0153405
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa -0.0152931
THOC7 THO complex 7 -0.0152809
SCLT1 sodium channel and clathrin linker 1 -0.0152424
PRLR prolactin receptor -0.0152017
WIPF1 WAS/WASL interacting protein family, member 1 -0.0151368
DPY19L4 dpy-19-like 4 (C. elegans) -0.0151067
MROH1 maestro heat-like repeat family member 1 -0.0150843
GSK3B glycogen synthase kinase 3 beta -0.015025
TUBA1B tubulin, alpha 1b -0.0150236
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.0149844
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) -0.0149699
TAOK3 TAO kinase 3 -0.0149147
SON SON DNA binding protein -0.0148866
CHD7 chromodomain helicase DNA binding protein 7 -0.0148658
GTF2IRD1 GTF2I repeat domain containing 1 -0.0148338
BIRC6 baculoviral IAP repeat containing 6 -0.0147564
SYNPO2 synaptopodin 2 -0.0147506
RDX radixin -0.0147037
QTMAN queuosine-tRNA mannosyltransferase -0.0146395
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.0146325
ACBD5 acyl-CoA binding domain containing 5 -0.0146257
SH3BP5 SH3-domain binding protein 5 (BTK-associated) -0.0146223
FMN1 formin 1 -0.0146089
SEL1L sel-1 suppressor of lin-12-like (C. elegans) -0.0145975
PRIM2 primase, DNA, polypeptide 2 (58kDa) -0.0145891
RPS14 ribosomal protein S14 -0.0145187
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 -0.0145111
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -0.014462
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) -0.0144148
ATL3 atlastin GTPase 3 -0.0144124
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.0143504
THADA thyroid adenoma associated -0.0143011
SRBD1 S1 RNA binding domain 1 -0.0142923
APP amyloid beta (A4) precursor protein -0.0142238
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 -0.0142108
TRIQK triple QxxK/R motif containing -0.0142091
BRD4 bromodomain containing 4 -0.0141997
CHD1L chromodomain helicase DNA binding protein 1-like -0.0141918
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 -0.0141862
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.0141407
SLC39A11 solute carrier family 39, member 11 -0.0141269
WDR70 WD repeat domain 70 -0.0141206
SLC35E3 solute carrier family 35, member E3 -0.0141192
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme -0.0141132
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 -0.0140803
SPPL3 signal peptide peptidase like 3 -0.0140777
RPL23A ribosomal protein L23a -0.0140689
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit -0.0139532
UGCG UDP-glucose ceramide glucosyltransferase -0.0139331
OSBPL1A oxysterol binding protein-like 1A -0.0138569
DCAF1 DDB1 and CUL4 associated factor 1 -0.0138545
CEP350 centrosomal protein 350kDa -0.0138542
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -0.0138361
MGMT O-6-methylguanine-DNA methyltransferase -0.013804
TBK1 TANK-binding kinase 1 -0.0137918
ZNF512B zinc finger protein 512B -0.0137879
ERP44 endoplasmic reticulum protein 44 -0.0137582
PKN1 protein kinase N1 -0.0136861
RBL1 retinoblastoma-like 1 -0.0136799
RAB22A RAB22A, member RAS oncogene family -0.0136603
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 -0.0136576
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0136568
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 -0.013651
RAB31 RAB31, member RAS oncogene family -0.0136069
FKBP4 FK506 binding protein 4, 59kDa -0.0135921
CLDN7 claudin 7 -0.013586
KAZN kazrin, periplakin interacting protein -0.0135764
RPS12 ribosomal protein S12 -0.013576
MAML2 mastermind-like 2 (Drosophila) -0.0135647
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -0.0135446
TIAM2 T-cell lymphoma invasion and metastasis 2 -0.0134765
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0134759
KANSL1 KAT8 regulatory NSL complex subunit 1 -0.0134427
RPL3 ribosomal protein L3 -0.0134262
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 -0.0133911
CCDC85C coiled-coil domain containing 85C -0.0133586
ZNF260 zinc finger protein 260 -0.0133222
EXOC4 exocyst complex component 4 -0.0133219
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A -0.0133052
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 -0.0132982
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -0.0132697
BBS9 Bardet-Biedl syndrome 9 -0.0132594
ORC4 origin recognition complex, subunit 4 -0.0132573
SFTPA2 surfactant protein A2 -0.0132552
CEMIP2 cell migration inducing hyaluronidase 2 -0.0132271
DOCK6 dedicator of cytokinesis 6 -0.0132264
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 -0.0132233
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) -0.0131915
MBTD1 mbt domain containing 1 -0.0131819
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.013156
SUMF2 sulfatase modifying factor 2 -0.0131372
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) -0.0130638
CSNK1A1 casein kinase 1, alpha 1 -0.0130289
KIAA1671 KIAA1671 -0.013008
NUP205 nucleoporin 205kDa -0.0129923
PARP1 poly (ADP-ribose) polymerase 1 -0.0129904
SAP130 Sin3A-associated protein, 130kDa -0.0129869
SRP72 signal recognition particle 72kDa -0.0129681
WDR59 WD repeat domain 59 -0.0129667
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -0.0129433
PRSS23 protease, serine, 23 -0.0129374
EPCAM epithelial cell adhesion molecule -0.0129297
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -0.0129014
GMCL1 germ cell-less, spermatogenesis associated 1 -0.0128756
SLTM SAFB-like, transcription modulator -0.0128672
RTN4RL1 reticulon 4 receptor-like 1 -0.0128234
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -0.0127671
GPR137B G protein-coupled receptor 137B -0.0127621
BRCA1 breast cancer 1, early onset -0.0127481
BCL7A B-cell CLL/lymphoma 7A -0.0127456
PUM1 pumilio RNA-binding family member 1 -0.0127418
LPP LIM domain containing preferred translocation partner in lipoma -0.0127232
PTER phosphotriesterase related -0.0127211
SPATA13 spermatogenesis associated 13 -0.012708
EZR ezrin -0.0126912
LCORL ligand dependent nuclear receptor corepressor-like -0.01266
NLK nemo-like kinase -0.0126328
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -0.0126269
SKI SKI proto-oncogene -0.0126253
EMC3 ER membrane protein complex subunit 3 -0.0126044
TBC1D22A TBC1 domain family, member 22A -0.0125878
WWC1 WW and C2 domain containing 1 -0.0125861
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0125477
REST RE1-silencing transcription factor -0.0125138
CEP295 centrosomal protein 295kDa -0.0125088
TMSB10 thymosin beta 10 -0.0124801
CASZ1 castor zinc finger 1 -0.01244
UBAC2 UBA domain containing 2 -0.0123817
TRA2A transformer 2 alpha homolog (Drosophila) -0.0123791
ADGRG6 adhesion G protein-coupled receptor G6 -0.0123657
SAMD8 sterile alpha motif domain containing 8 -0.0123609
XYLT1 xylosyltransferase I -0.0123605
CUL2 cullin 2 -0.0123314
PRPF38B pre-mRNA processing factor 38B -0.0123274
DPY30 dpy-30 homolog (C. elegans) -0.0123215
CDCA5 cell division cycle associated 5 -0.0123119
MSH2 mutS homolog 2 -0.0123041
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L -0.0122961
MARCHF6 membrane associated ring-CH-type finger 6 -0.0122859
LAMP2 lysosomal-associated membrane protein 2 -0.0122493
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 -0.0122477
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains -0.0122434
TASP1 taspase, threonine aspartase, 1 -0.0122264
CLIC1 chloride intracellular channel 1 -0.012221
WDR1 WD repeat domain 1 -0.0122114
VSIG10 V-set and immunoglobulin domain containing 10 -0.0122027
PRPF39 pre-mRNA processing factor 39 -0.012167
ITPK1 inositol-tetrakisphosphate 1-kinase -0.0121626
ZNF721 zinc finger protein 721 -0.0121369
RNASE7 ribonuclease, RNase A family, 7 -0.0121078
SMAD3 SMAD family member 3 -0.0120965
DPP8 dipeptidyl-peptidase 8 -0.0120878
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) -0.0120863
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -0.0120846
WWP2 WW domain containing E3 ubiquitin protein ligase 2 -0.0120667
PCED1B PC-esterase domain containing 1B -0.0120541
NOL11 nucleolar protein 11 -0.0120317
CLTC clathrin, heavy chain (Hc) -0.0120286
EXD3 exonuclease 3'-5' domain containing 3 -0.0120194
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -0.0120185
UQCRH ubiquinol-cytochrome c reductase hinge protein -0.0119811
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa -0.0119502
INO80D INO80 complex subunit D -0.0119475
HELZ2 helicase with zinc finger 2, transcriptional coactivator -0.0119383
FIRRM FIGNL1 interacting regulator of recombination and mitosis -0.0119312
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.0119278
TATDN1 TatD DNase domain containing 1 -0.0118986
RAB8A RAB8A, member RAS oncogene family -0.0118782
TBL1X transducin (beta)-like 1X-linked -0.0118652
YME1L1 YME1-like 1 ATPase -0.0117784
TMOD3 tropomodulin 3 (ubiquitous) -0.0117601
NFX1 nuclear transcription factor, X-box binding 1 -0.0117543
UBXN7 UBX domain protein 7 -0.0117494
DMXL2 Dmx-like 2 -0.0117421
ZNF292 zinc finger protein 292 -0.0117414
GPR107 G protein-coupled receptor 107 -0.011728
PRDX2 peroxiredoxin 2 -0.0117232
SUMO2 small ubiquitin-like modifier 2 -0.0117042
IQANK1 IQ motif and ankyrin repeat containing 1 -0.011675