MCF7_GSK-LSD1 2HCl_10nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description GSK-LSD1 2HCl 10nM perturbation in MCF7 cell line at 24h timepoint (Sci-Plex)
Similar Terms
Downloads & Tools

Genes

1000 genes differentially expressed following the MCF7_GSK-LSD1 2HCl_10nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
CTSD cathepsin D 0.198385
TTC28 tetratricopeptide repeat domain 28 0.171109
OVOL2 ovo-like zinc finger 2 0.15296
TFF1 trefoil factor 1 0.147461
NCOA3 nuclear receptor coactivator 3 0.117217
TRIM37 tripartite motif containing 37 0.106185
THSD4 thrombospondin, type I, domain containing 4 0.0897723
BCAS3 breast carcinoma amplified sequence 3 0.0873881
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 0.0864392
MSI2 musashi RNA-binding protein 2 0.0861739
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0826784
MALRD1 MAM and LDL receptor class A domain containing 1 0.0817796
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.0817338
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 0.0741983
FLNA filamin A, alpha 0.0697831
TPM4 tropomyosin 4 0.0663263
CYRIB CYFIP related Rac1 interactor B 0.0647028
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 0.0604663
HIP1 huntingtin interacting protein 1 0.058867
RAD51C RAD51 paralog C 0.0566476
RNF115 ring finger protein 115 0.0549752
NRIP1 nuclear receptor interacting protein 1 0.0518172
EXOC4 exocyst complex component 4 0.0509752
RHPN2 rhophilin, Rho GTPase binding protein 2 0.050604
GPC6 glypican 6 0.0502771
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.0463564
NBEA neurobeachin 0.0453642
PRAG1 PEAK1 related, kinase-activating pseudokinase 1 0.0451699
SOGA1 suppressor of glucose, autophagy associated 1 0.0449624
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.0443006
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0442649
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 0.0440998
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.0437595
PHACTR4 phosphatase and actin regulator 4 0.0434318
DCAF7 DDB1 and CUL4 associated factor 7 0.0427975
SPIDR scaffolding protein involved in DNA repair 0.0425317
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.042193
MPHOSPH9 M-phase phosphoprotein 9 0.0403704
UGDH UDP-glucose 6-dehydrogenase 0.0401592
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.0397692
R3HDM1 R3H domain containing 1 0.0397429
SACS sacsin molecular chaperone 0.039526
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 0.0394405
MAST4 microtubule associated serine/threonine kinase family member 4 0.0385962
GFRA1 GDNF family receptor alpha 1 0.0384842
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.0382441
VMP1 vacuole membrane protein 1 0.0382097
ANKRD28 ankyrin repeat domain 28 0.038094
RBM6 RNA binding motif protein 6 0.0371528
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 0.0370156
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0366646
POGZ pogo transposable element with ZNF domain 0.0351391
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.0341863
TANGO6 transport and golgi organization 6 homolog (Drosophila) 0.0341767
TSPAN12 tetraspanin 12 0.0340529
TUBB tubulin, beta class I 0.0333548
GREB1 growth regulation by estrogen in breast cancer 1 0.0333004
GRHL2 grainyhead-like 2 (Drosophila) 0.0331277
APRT adenine phosphoribosyltransferase 0.032999
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 0.0327417
LGALS3 lectin, galactoside-binding, soluble, 3 0.0324863
SP3 Sp3 transcription factor 0.0322215
TTBK2 tau tubulin kinase 2 0.0314549
CLDN3 claudin 3 0.0313768
PGR progesterone receptor 0.0313499
ELOVL2 ELOVL fatty acid elongase 2 0.0312669
LARP1 La ribonucleoprotein domain family, member 1 0.0311682
XPR1 xenotropic and polytropic retrovirus receptor 1 0.0310588
CEP350 centrosomal protein 350kDa 0.030936
ATXN2 ataxin 2 0.0308107
ELP2 elongator acetyltransferase complex subunit 2 0.0307795
SVIL supervillin 0.0307061
SPPL2A signal peptide peptidase like 2A 0.0304131
ITGB5 integrin, beta 5 0.0303514
EEIG1 estrogen-induced osteoclastogenesis regulator 1 0.0303046
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.0302478
PKN2 protein kinase N2 0.0301482
DSTN destrin (actin depolymerizing factor) 0.0300993
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta 0.0300562
ATAD2 ATPase family, AAA domain containing 2 0.0300165
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.0299158
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 0.029503
NSD2 nuclear receptor binding SET domain protein 2 0.0294947
CMSS1 cms1 ribosomal small subunit homolog (yeast) 0.0292962
SGMS1 sphingomyelin synthase 1 0.0292746
ULK1 unc-51 like autophagy activating kinase 1 0.0289936
PTPRG protein tyrosine phosphatase, receptor type, G 0.028709
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 0.0284586
RBL2 retinoblastoma-like 2 0.0283724
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0282405
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.0280788
RASA2 RAS p21 protein activator 2 0.0279992
MLEC malectin 0.0279967
NRG3 neuregulin 3 0.027906
RABGAP1L RAB GTPase activating protein 1-like 0.0279029
PATJ PATJ crumbs cell polarity complex component 0.0276722
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.0272045
ACTN1 actinin, alpha 1 0.0270562
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.0269917
AOPEP aminopeptidase O (putative) 0.0268419
ASXL1 additional sex combs like transcriptional regulator 1 0.0268217
NCOA1 nuclear receptor coactivator 1 0.0268186
GRAMD1A GRAM domain containing 1A 0.0267523
CEP170 centrosomal protein 170kDa 0.0267248
SLC35F5 solute carrier family 35, member F5 0.0267196
PCNX4 pecanex 4 0.0266298
ECE1 endothelin converting enzyme 1 0.0264701
MTSS1 metastasis suppressor 1 0.0264588
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 0.0260589
STC2 stanniocalcin 2 0.0260384
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 0.025949
EPHA6 EPH receptor A6 0.0259433
MED13L mediator complex subunit 13-like 0.0259377
DIAPH2 diaphanous-related formin 2 0.0257701
SFXN5 sideroflexin 5 0.025697
TMEM120B transmembrane protein 120B 0.0256658
LITAF lipopolysaccharide-induced TNF factor 0.0256393
ATOSA atos homolog A 0.0255304
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 0.025232
FGF12 fibroblast growth factor 12 0.0252256
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.0251741
NCAM2 neural cell adhesion molecule 2 0.0251533
ATF7IP activating transcription factor 7 interacting protein 0.0249333
RTN3 reticulon 3 0.024863
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.0247269
ACTN4 actinin, alpha 4 0.0247172
CDYL2 chromodomain protein, Y-like 2 0.024481
SAMD12 sterile alpha motif domain containing 12 0.0243929
COL5A1 collagen, type V, alpha 1 0.0242566
RNFT2 ring finger protein, transmembrane 2 0.0242221
PCNX1 pecanex 1 0.0240849
EEF2 eukaryotic translation elongation factor 2 0.0240625
IDE insulin-degrading enzyme 0.0240519
ZMYND8 zinc finger, MYND-type containing 8 0.0240221
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.0240109
STX8 syntaxin 8 0.023952
BRI3BP BRI3 binding protein 0.0238573
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0237523
MYO9A myosin IXA 0.0236988
DENND1A DENN/MADD domain containing 1A 0.0236882
DOCK4 dedicator of cytokinesis 4 0.0235868
ADIPOR2 adiponectin receptor 2 0.0234885
TTC17 tetratricopeptide repeat domain 17 0.0233134
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 0.0232903
AHNAK2 AHNAK nucleoprotein 2 0.0232292
RBL1 retinoblastoma-like 1 0.0231585
WAC WW domain containing adaptor with coiled-coil 0.0230228
EPS15 epidermal growth factor receptor pathway substrate 15 0.0229534
FERMT2 fermitin family member 2 0.0229309
RAB11FIP3 RAB11 family interacting protein 3 (class II) 0.0229094
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.0229043
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.022904
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 0.0228374
TMEM192 transmembrane protein 192 0.0228097
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.0226722
ELOVL5 ELOVL fatty acid elongase 5 0.0226353
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0225717
ARSG arylsulfatase G 0.0225575
NKTR natural killer cell triggering receptor 0.0224482
SFXN1 sideroflexin 1 0.022316
VAV2 vav 2 guanine nucleotide exchange factor 0.0222585
PRPF3 pre-mRNA processing factor 3 0.0221932
UBTF upstream binding transcription factor, RNA polymerase I 0.0221269
ANXA6 annexin A6 0.0220813
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 0.0220617
SLC44A2 solute carrier family 44 (choline transporter), member 2 0.0219997
CYB561 cytochrome b561 0.0218988
ABHD12 abhydrolase domain containing 12 0.0218674
TNRC6C trinucleotide repeat containing 6C 0.0218178
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.0217791
INVS inversin 0.021704
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.0216392
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.0216196
SESTD1 SEC14 and spectrin domains 1 0.021298
RNASE12 ribonuclease, RNase A family, 12 (non-active) 0.0212135
ZEB1 zinc finger E-box binding homeobox 1 0.0211557
ZRANB3 zinc finger, RAN-binding domain containing 3 0.0211494
HSH2D hematopoietic SH2 domain containing 0.0211154
TIMP3 TIMP metallopeptidase inhibitor 3 0.0210521
AEBP2 AE binding protein 2 0.0210204
CCNI cyclin I 0.0210152
SCAI suppressor of cancer cell invasion 0.0209574
MECP2 methyl CpG binding protein 2 0.0209288
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.0209047
UBXN4 UBX domain protein 4 0.020879
ENOX2 ecto-NOX disulfide-thiol exchanger 2 0.0208693
BASP1 brain abundant, membrane attached signal protein 1 0.0207142
PARP4 poly (ADP-ribose) polymerase family, member 4 0.0206848
GOLGA2 golgin A2 0.0206808
FBP1 fructose-1,6-bisphosphatase 1 0.0206653
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0205987
QSER1 glutamine and serine rich 1 0.0205718
CAPN8 calpain 8 0.0205198
NCKAP5 NCK-associated protein 5 0.0203744
DTNB dystrobrevin, beta 0.0202607
CTNND2 catenin (cadherin-associated protein), delta 2 0.0202493
CLDN7 claudin 7 0.0202192
LCLAT1 lysocardiolipin acyltransferase 1 0.0201955
TPI1 triosephosphate isomerase 1 0.0200865
SREBF2 sterol regulatory element binding transcription factor 2 0.0200755
CEP112 centrosomal protein 112kDa 0.0200224
FCHSD2 FCH and double SH3 domains 2 0.0200035
SLC38A1 solute carrier family 38, member 1 0.0199731
CUEDC1 CUE domain containing 1 0.0199596
LARP4 La ribonucleoprotein domain family, member 4 0.0199413
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 0.0198409
USP32 ubiquitin specific peptidase 32 0.0198359
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) 0.0198339
ATAD2B ATPase family, AAA domain containing 2B 0.0198162
AUTS2 autism susceptibility candidate 2 0.0197883
PTPRF protein tyrosine phosphatase, receptor type, F 0.0197754
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.0197189
SNX14 sorting nexin 14 0.0196081
PLEC plectin 0.0195546
CEP135 centrosomal protein 135kDa 0.0194625
MYH9 myosin, heavy chain 9, non-muscle 0.0194541
PRKCE protein kinase C, epsilon 0.0194116
VCL vinculin 0.0193334
GAB2 GRB2-associated binding protein 2 0.019209
TNRC6B trinucleotide repeat containing 6B 0.0191942
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 0.0191207
DPP8 dipeptidyl-peptidase 8 0.0191003
RBM39 RNA binding motif protein 39 0.0190238
IKBIP IKBKB interacting protein 0.0189453
CLSTN2 calsyntenin 2 0.0188943
BTBD1 BTB (POZ) domain containing 1 0.0188664
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.0188507
ITPK1 inositol-tetrakisphosphate 1-kinase 0.0188469
MAML3 mastermind-like 3 (Drosophila) 0.0188384
UIMC1 ubiquitin interaction motif containing 1 0.0187974
TRAP1 TNF receptor-associated protein 1 0.0186412
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.0186215
NUCB2 nucleobindin 2 0.0185131
SQLE squalene epoxidase 0.0185046
CLOCK clock circadian regulator 0.0185014
FKBP4 FK506 binding protein 4, 59kDa 0.0184741
PTEN phosphatase and tensin homolog 0.0184703
FBXO11 F-box protein 11 0.0184351
POLK polymerase (DNA directed) kappa 0.0184312
SIPA1L3 signal-induced proliferation-associated 1 like 3 0.0184302
DCAF5 DDB1 and CUL4 associated factor 5 0.0184161
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.0184118
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase 0.018348
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.0182248
LOC102724023 ES1 protein homolog, mitochondrial 0.018175
PRR14L proline rich 14-like 0.0181545
SENP1 SUMO1/sentrin specific peptidase 1 0.0181285
VASP vasodilator-stimulated phosphoprotein 0.018126
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 0.018119
ABHD18 abhydrolase domain containing 18 0.0180872
MYO1D myosin ID 0.0179919
SRPK1 SRSF protein kinase 1 0.0178831
MIA3 melanoma inhibitory activity family, member 3 0.0178232
BTF3L4 basic transcription factor 3-like 4 0.0178226
AMBRA1 autophagy/beclin-1 regulator 1 0.0177871
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0177745
PKM pyruvate kinase, muscle 0.0177316
GSTM3 glutathione S-transferase mu 3 (brain) 0.0177116
PICALM phosphatidylinositol binding clathrin assembly protein 0.017674
ICA1 islet cell autoantigen 1, 69kDa 0.017669
SEPTIN9 septin 9 0.0176345
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.01758
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.0175658
MICU1 mitochondrial calcium uptake 1 0.0175599
CBR4 carbonyl reductase 4 0.0175406
TULP4 tubby like protein 4 0.0175284
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0175121
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.0174513
CHD9 chromodomain helicase DNA binding protein 9 0.0174398
ATXN7 ataxin 7 0.0174262
DMXL2 Dmx-like 2 0.0174008
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 0.0173819
PEAK1 pseudopodium-enriched atypical kinase 1 0.0173518
IARS1 isoleucyl-tRNA synthetase 1 0.0172988
XRN2 5'-3' exoribonuclease 2 0.0172667
HDGFL3 HDGF like 3 0.0171704
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0171334
SERINC1 serine incorporator 1 0.0170968
CDC27 cell division cycle 27 0.0170852
TNPO3 transportin 3 0.0169943
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.016914
DDHD1 DDHD domain containing 1 0.0169031
RAD23B RAD23 homolog B (S. cerevisiae) 0.0168901
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 0.0168465
NUP160 nucleoporin 160kDa 0.0168174
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0168063
LARP1B La ribonucleoprotein domain family, member 1B 0.0167398
ACBD3 acyl-CoA binding domain containing 3 0.0167097
NPEPL1 aminopeptidase-like 1 0.0166317
BTBD7 BTB (POZ) domain containing 7 0.0166233
MAP7D3 MAP7 domain containing 3 0.0166162
IL27RA interleukin 27 receptor, alpha 0.0165836
RGS6 regulator of G-protein signaling 6 0.0165707
TOR1AIP1 torsin A interacting protein 1 0.0165342
LRPPRC leucine-rich pentatricopeptide repeat containing 0.016487
STXBP1 syntaxin binding protein 1 0.0164586
PDZD8 PDZ domain containing 8 0.016284
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.0162752
NVL nuclear VCP-like 0.0162744
RHBDD1 rhomboid domain containing 1 0.0162732
SMC5 structural maintenance of chromosomes 5 0.0162704
NPNT nephronectin 0.0162121
ZNF43 zinc finger protein 43 0.0161958
PPL periplakin 0.0161727
SLC35D4 solute carrier family 35 member D4 0.0161428
GTF2IRD1 GTF2I repeat domain containing 1 0.0161137
C14ORF132 chromosome 14 open reading frame 132 0.0161
PRELID1 PRELI domain containing 1 0.016085
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 0.0160799
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.016041
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.0160051
TOP1 topoisomerase (DNA) I 0.016002
ZNF644 zinc finger protein 644 0.0159638
SIL1 SIL1 nucleotide exchange factor 0.0159621
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 0.0159549
RPS15 ribosomal protein S15 0.0159527
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.0159387
PEDS1 plasmanylethanolamine desaturase 1 0.01592
XPO5 exportin 5 0.0159027
TASP1 taspase, threonine aspartase, 1 0.0158983
SERF2 small EDRK-rich factor 2 0.0158663
CDK12 cyclin-dependent kinase 12 0.0158632
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) 0.0158445
GANAB glucosidase, alpha; neutral AB 0.0158274
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) 0.0157737
CERS6 ceramide synthase 6 0.0156637
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.0156529
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 0.0156312
PDS5A PDS5 cohesin associated factor A 0.0156202
LRP10 low density lipoprotein receptor-related protein 10 0.0156162
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0156138
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.0155944
NBPF15 neuroblastoma breakpoint family, member 15 0.0155474
TM9SF3 transmembrane 9 superfamily member 3 0.0155377
KRTAP11-1 keratin associated protein 11-1 0.0155336
PPP1R9A protein phosphatase 1, regulatory subunit 9A 0.0155282
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.0155036
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0154861
DSTYK dual serine/threonine and tyrosine protein kinase 0.0154651
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 0.0154559
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.015438
PAWR PRKC, apoptosis, WT1, regulator 0.0154269
IGFBP4 insulin-like growth factor binding protein 4 0.0154031
TLK1 tousled-like kinase 1 0.0153712
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 0.0153484
CD47 CD47 molecule 0.015305
DGKH diacylglycerol kinase, eta 0.0152988
KPNA6 karyopherin alpha 6 (importin alpha 7) 0.01529
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 0.0152837
OLA1 Obg-like ATPase 1 0.0152758
LIN52 lin-52 DREAM MuvB core complex component 0.0152335
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.0152089
ZNF217 zinc finger protein 217 0.0152
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.0151907
STOM stomatin 0.0151721
ETFA electron-transfer-flavoprotein, alpha polypeptide 0.015154
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 0.015129
SAP130 Sin3A-associated protein, 130kDa 0.015126
UBE2M ubiquitin-conjugating enzyme E2M 0.0151112
NT5DC3 5'-nucleotidase domain containing 3 0.0151036
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.0150677
ACBD6 acyl-CoA binding domain containing 6 0.0150667
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 0.0150457
RRAS2 related RAS viral (r-ras) oncogene homolog 2 0.0150342
GMDS GDP-mannose 4,6-dehydratase 0.0150104
IER2 immediate early response 2 0.0150098
PTPN2 protein tyrosine phosphatase, non-receptor type 2 0.0149856
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0149659
MYOF myoferlin 0.0149573
MAN1B1 mannosidase, alpha, class 1B, member 1 0.0148936
ADGRA3 adhesion G protein-coupled receptor A3 0.0148925
ZHX2 zinc fingers and homeoboxes 2 0.0148558
DENND5B DENN/MADD domain containing 5B 0.0148444
NIBAN2 niban apoptosis regulator 2 0.0148155
SYNGR2 synaptogyrin 2 0.0148075
FLOT2 flotillin 2 0.0147572
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.014708
MAGED2 melanoma antigen family D2 0.0146957
NR2C1 nuclear receptor subfamily 2, group C, member 1 0.0146562
SRRM2 serine/arginine repetitive matrix 2 0.014651
STARD10 StAR-related lipid transfer (START) domain containing 10 0.01464
PER2 period circadian clock 2 0.0146206
ERBB3 erb-b2 receptor tyrosine kinase 3 0.01462
MRPS23 mitochondrial ribosomal protein S23 0.0146188
DOK7 docking protein 7 0.0146122
NEK8 NIMA-related kinase 8 0.0145621
MGP matrix Gla protein 0.0145506
WDR12 WD repeat domain 12 0.0145482
SSH2 slingshot protein phosphatase 2 0.014545
ARHGAP32 Rho GTPase activating protein 32 0.014527
OSBPL10 oxysterol binding protein-like 10 0.0145253
SCAF11 SR-related CTD-associated factor 11 0.0145249
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.0145192
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.0145117
TRA2A transformer 2 alpha homolog (Drosophila) 0.0144705
TPD52 tumor protein D52 0.0144658
CHN1 chimerin 1 0.0144583
EGR1 early growth response 1 0.0144172
RSL1D1 ribosomal L1 domain containing 1 0.0144103
SEC62 SEC62 homolog (S. cerevisiae) 0.0144058
USP48 ubiquitin specific peptidase 48 0.0143983
MAP3K2 mitogen-activated protein kinase kinase kinase 2 0.0143321
CCND3 cyclin D3 0.0142909
SH3KBP1 SH3-domain kinase binding protein 1 0.0142907
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 0.0142789
METRN meteorin, glial cell differentiation regulator 0.0142723
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.0142641
PRKCA protein kinase C, alpha 0.01426
EPCAM epithelial cell adhesion molecule 0.0142397
PTPRE protein tyrosine phosphatase, receptor type, E 0.014238
ZNF331 zinc finger protein 331 0.0142364
MUC16 mucin 16, cell surface associated 0.0142309
PCYOX1 prenylcysteine oxidase 1 0.0142229
STK39 serine threonine kinase 39 0.0142144
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 0.0141941
PPA2 pyrophosphatase (inorganic) 2 0.0141825
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 0.0141593
MCM3AP minichromosome maintenance complex component 3 associated protein 0.0141579
TRA2B transformer 2 beta homolog (Drosophila) 0.0141363
PCCA propionyl CoA carboxylase, alpha polypeptide 0.0140913
MAP2K5 mitogen-activated protein kinase kinase 5 0.01409
MUC1 mucin 1, cell surface associated 0.0140786
TSC1 tuberous sclerosis 1 0.0140423
PRRC2C proline-rich coiled-coil 2C 0.0140256
DCAF6 DDB1 and CUL4 associated factor 6 0.0140182
NAP1L4 nucleosome assembly protein 1-like 4 0.0140052
LSG1 large 60S subunit nuclear export GTPase 1 0.0139869
CSPP1 centrosome and spindle pole associated protein 1 0.013963
TEX2 testis expressed 2 0.0139596
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.0139473
ZDHHC20 zinc finger, DHHC-type containing 20 0.0139321
GRID1 glutamate receptor, ionotropic, delta 1 0.0139142
MGA MGA, MAX dimerization protein 0.0139109
C5AR2 complement component 5a receptor 2 0.0138665
HDAC8 histone deacetylase 8 0.0138533
RPL5 ribosomal protein L5 0.0138304
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 0.0138104
AGO3 argonaute RISC catalytic component 3 0.0137912
ATL2 atlastin GTPase 2 0.0137902
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.0137776
GK5 glycerol kinase 5 (putative) 0.0137576
TXLNA taxilin alpha 0.0137575
GPRC5C G protein-coupled receptor, class C, group 5, member C 0.0137389
CDH18 cadherin 18, type 2 0.0137234
ARL5B ADP-ribosylation factor-like 5B 0.0137127
RPS2 ribosomal protein S2 0.0136572
MAP2K2 mitogen-activated protein kinase kinase 2 0.0136478
PCM1 pericentriolar material 1 0.0136381
GOLIM4 golgi integral membrane protein 4 0.0136081
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.0135591
CABIN1 calcineurin binding protein 1 0.0135545
RB1 retinoblastoma 1 0.0135525
DGKD diacylglycerol kinase, delta 130kDa 0.0135164
PODXL podocalyxin-like 0.0135029
ZNF592 zinc finger protein 592 0.0134818
YME1L1 YME1-like 1 ATPase 0.0134626
FAM193A family with sequence similarity 193, member A 0.0134587
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0134523
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.0134117
SCFD1 sec1 family domain containing 1 0.0134017
PTGFRN prostaglandin F2 receptor inhibitor 0.013374
CD109 CD109 molecule 0.0133495
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa 0.0133316
UBE2I ubiquitin-conjugating enzyme E2I 0.0133281
RILPL1 Rab interacting lysosomal protein-like 1 0.0133172
PRKCH protein kinase C, eta 0.0133153
P3H1 prolyl 3-hydroxylase 1 0.0132504
TEX14 testis expressed 14 0.0132424
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 0.0132284
RNF223 ring finger protein 223 0.013228
NME7 NME/NM23 family member 7 0.0131792
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.0131752
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.0131618
OSBPL6 oxysterol binding protein-like 6 0.0131566
IP6K1 inositol hexakisphosphate kinase 1 0.0131485
NXNL2 nucleoredoxin-like 2 0.0131452
RHOU ras homolog family member U 0.013144
EXOC5 exocyst complex component 5 0.0131371
TTC21B tetratricopeptide repeat domain 21B 0.0131305
MED12 mediator complex subunit 12 0.0131132
FNDC3A fibronectin type III domain containing 3A 0.0130908
PHTF1 putative homeodomain transcription factor 1 0.0130868
CCDC88C coiled-coil domain containing 88C 0.0130732
SRSF4 serine/arginine-rich splicing factor 4 0.0130022
TMEM131 transmembrane protein 131 0.0130016
C5ORF24 chromosome 5 open reading frame 24 0.0129785
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.0129674
COX5A cytochrome c oxidase subunit Va 0.0129291
CEMIP2 cell migration inducing hyaluronidase 2 0.0128829
EFHC1 EF-hand domain (C-terminal) containing 1 0.0128767
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 0.0128622
PRKCSH protein kinase C substrate 80K-H 0.0128444
PKNOX1 PBX/knotted 1 homeobox 1 0.0128128
GOLPH3 golgi phosphoprotein 3 (coat-protein) 0.0128097
SUCO SUN domain containing ossification factor 0.0128063
JADE1 jade family PHD finger 1 0.0128049
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.0128004
KIAA0319L KIAA0319-like 0.0127997
CNPY2 canopy FGF signaling regulator 2 0.0127943
H2AZ1 H2A.Z variant histone 1 0.0127573

decreased expression

Symbol Name Standardized Value
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.138042
AGR2 anterior gradient 2 -0.117897
DSPP dentin sialophosphoprotein -0.112097
NRCAM neuronal cell adhesion molecule -0.106701
GATA3 GATA binding protein 3 -0.103428
IGF1R insulin-like growth factor 1 receptor -0.0907267
SYTL2 synaptotagmin-like 2 -0.0838616
JARID2 jumonji, AT rich interactive domain 2 -0.0831776
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.0774685
BPTF bromodomain PHD finger transcription factor -0.07651
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.0717978
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.0678124
TUBD1 tubulin, delta 1 -0.0648173
SDK1 sidekick cell adhesion molecule 1 -0.0632953
ATXN1 ataxin 1 -0.0613672
CCSER1 coiled-coil serine-rich protein 1 -0.0605086
IFI6 interferon, alpha-inducible protein 6 -0.0601226
RPL13A ribosomal protein L13a -0.0562718
ANKRD11 ankyrin repeat domain 11 -0.0557885
KRT18 keratin 18, type I -0.0546152
GNAS GNAS complex locus -0.0543362
RPS6 ribosomal protein S6 -0.051772
CUX1 cut-like homeobox 1 -0.0503917
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -0.0497529
GSK3B glycogen synthase kinase 3 beta -0.0466011
SULF2 sulfatase 2 -0.0463167
MRPL13 mitochondrial ribosomal protein L13 -0.044844
NRP1 neuropilin 1 -0.0447291
TRPS1 trichorhinophalangeal syndrome I -0.0437087
EVL Enah/Vasp-like -0.043515
CSDE1 cold shock domain containing E1, RNA-binding -0.0425108
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0414548
KDM2A lysine (K)-specific demethylase 2A -0.0413908
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0413876
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 -0.0410471
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0405008
TMEM64 transmembrane protein 64 -0.0404053
RPL12 ribosomal protein L12 -0.040076
CALCR calcitonin receptor -0.0398426
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide -0.0396241
AREG amphiregulin -0.0387706
PRR11 proline rich 11 -0.0386756
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.0381562
SETD5 SET domain containing 5 -0.0377074
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0372167
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein -0.0371433
RUNX1 runt-related transcription factor 1 -0.0367597
RAD51B RAD51 paralog B -0.0363084
ESRP1 epithelial splicing regulatory protein 1 -0.0362217
SORT1 sortilin 1 -0.0358702
SPATS2L spermatogenesis associated, serine-rich 2-like -0.0350954
RHOBTB3 Rho-related BTB domain containing 3 -0.034501
HSPB1 heat shock 27kDa protein 1 -0.0344018
FOXP1 forkhead box P1 -0.0343085
SACK1B scaffolding CK1 anchoring protein B -0.0340856
ADAR adenosine deaminase, RNA-specific -0.0339192
KRT19 keratin 19, type I -0.0337433
HNRNPF heterogeneous nuclear ribonucleoprotein F -0.0335743
DTNA dystrobrevin, alpha -0.032994
IGFBP5 insulin-like growth factor binding protein 5 -0.0326608
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.0325937
TMCC1 transmembrane and coiled-coil domain family 1 -0.0324102
CTCF CCCTC-binding factor (zinc finger protein) -0.0323416
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -0.0320543
MYO1E myosin IE -0.0315309
TUG1 taurine up-regulated 1 (non-protein coding) -0.0312562
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains -0.0303203
TUBA1B tubulin, alpha 1b -0.0301725
EXOC6B exocyst complex component 6B -0.0301633
FOXO3 forkhead box O3 -0.0300305
IRS1 insulin receptor substrate 1 -0.0298953
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) -0.0296042
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 -0.0295618
MAP4 microtubule-associated protein 4 -0.0294556
BCAS1 breast carcinoma amplified sequence 1 -0.0293809
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0293448
MYO6 myosin VI -0.0293396
RORA RAR-related orphan receptor A -0.0293063
SMAD3 SMAD family member 3 -0.0288759
HDLBP high density lipoprotein binding protein -0.028868
KRT8 keratin 8, type II -0.0288184
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.0286936
ADGRG6 adhesion G protein-coupled receptor G6 -0.0281326
TRIM33 tripartite motif containing 33 -0.0281235
RAB2A RAB2A, member RAS oncogene family -0.027869
GPHN gephyrin -0.027815
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.027501
BAZ1A bromodomain adjacent to zinc finger domain, 1A -0.0266393
RPL32 ribosomal protein L32 -0.0264482
FAF1 Fas (TNFRSF6) associated factor 1 -0.0263827
SCAMP2 secretory carrier membrane protein 2 -0.026382
SENP6 SUMO1/sentrin specific peptidase 6 -0.0263736
TET2 tet methylcytosine dioxygenase 2 -0.0263638
SKA2 spindle and kinetochore associated complex subunit 2 -0.0263259
NPAS3 neuronal PAS domain protein 3 -0.026199
WSB1 WD repeat and SOCS box containing 1 -0.0253849
XPO1 exportin 1 -0.02535
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase -0.0253207
UBC ubiquitin C -0.0252984
MLPH melanophilin -0.0252003
PBX3 pre-B-cell leukemia homeobox 3 -0.0250628
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0249683
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.0249516
ITPRID2 ITPR interacting domain containing 2 -0.0248644
RPLP2 ribosomal protein, large, P2 -0.0247647
STK38 serine/threonine kinase 38 -0.0244451
KTN1 kinectin 1 (kinesin receptor) -0.024396
CADM1 cell adhesion molecule 1 -0.0243694
CDK6 cyclin-dependent kinase 6 -0.0242035
DSCAM Down syndrome cell adhesion molecule -0.0241321
RPL4 ribosomal protein L4 -0.0240675
PKP4 plakophilin 4 -0.023989
MEF2A myocyte enhancer factor 2A -0.0239017
MAP3K20 mitogen-activated protein kinase kinase kinase 20 -0.0237217
C1ORF21 chromosome 1 open reading frame 21 -0.0236994
NT5C2 5'-nucleotidase, cytosolic II -0.0236388
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 -0.0235302
GATAD2A GATA zinc finger domain containing 2A -0.0234874
ZNF638 zinc finger protein 638 -0.0232915
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.0232847
RPL14 ribosomal protein L14 -0.0232083
GOLGA4 golgin A4 -0.0230382
CDYL chromodomain protein, Y-like -0.0228942
ATP9A ATPase, class II, type 9A -0.0228779
NCOA2 nuclear receptor coactivator 2 -0.0228683
STRBP spermatid perinuclear RNA binding protein -0.0228091
SLC39A11 solute carrier family 39, member 11 -0.0227027
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0226145
EPN2 epsin 2 -0.0225469
IFI27 interferon, alpha-inducible protein 27 -0.0223971
DCDC2 doublecortin domain containing 2 -0.0223569
HLA-E major histocompatibility complex, class I, E -0.0220601
SEC11A SEC11 homolog A (S. cerevisiae) -0.0220459
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -0.0219817
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0219489
SERINC5 serine incorporator 5 -0.021658
ANO6 anoctamin 6 -0.0215094
PLXDC2 plexin domain containing 2 -0.0214703
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -0.0214513
DPYD dihydropyrimidine dehydrogenase -0.0214343
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) -0.0214084
AKAP9 A kinase (PRKA) anchor protein 9 -0.0213872
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.021377
SYNGAP1 synaptic Ras GTPase activating protein 1 -0.0213492
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -0.0212953
SNX6 sorting nexin 6 -0.0211873
CD81 CD81 molecule -0.021183
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0211541
TNRC18 trinucleotide repeat containing 18 -0.0210862
PDIA6 protein disulfide isomerase family A, member 6 -0.021059
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.0209825
HIPK2 homeodomain interacting protein kinase 2 -0.0209164
BMP7 bone morphogenetic protein 7 -0.0209062
ASCC3 activating signal cointegrator 1 complex subunit 3 -0.0209003
EMP2 epithelial membrane protein 2 -0.0207423
HACD2 3-hydroxyacyl-CoA dehydratase 2 -0.0207083
NBAS neuroblastoma amplified sequence -0.0205936
UBL3 ubiquitin-like 3 -0.0205446
DNM2 dynamin 2 -0.0204334
IFITM3 interferon induced transmembrane protein 3 -0.0202912
ARHGAP35 Rho GTPase activating protein 35 -0.020251
BICDL1 BICD family like cargo adaptor 1 -0.0201785
PIKFYVE phosphoinositide kinase, FYVE finger containing -0.020137
AAK1 AP2 associated kinase 1 -0.0200885
RAB31 RAB31, member RAS oncogene family -0.0200498
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 -0.0198836
EPB41L1 erythrocyte membrane protein band 4.1-like 1 -0.0198781
RNF168 ring finger protein 168, E3 ubiquitin protein ligase -0.0198212
SET SET nuclear proto-oncogene -0.0198152
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -0.0197487
DOP1B DOP1 leucine zipper like protein B -0.0197193
BRCA1 breast cancer 1, early onset -0.019717
EFCAB14 EF-hand calcium binding domain 14 -0.0197033
RPS25 ribosomal protein S25 -0.0196913
TMBIM6 transmembrane BAX inhibitor motif containing 6 -0.0196913
KMT2C lysine (K)-specific methyltransferase 2C -0.0196878
TENM3 teneurin transmembrane protein 3 -0.0196584
TUT7 terminal uridylyl transferase 7 -0.0196391
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -0.019628
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -0.0195935
TPT1 tumor protein, translationally-controlled 1 -0.0195052
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.0194722
SOX4 SRY (sex determining region Y)-box 4 -0.0193961
ZNF721 zinc finger protein 721 -0.0193813
NEBL nebulette -0.0193322
CFAP44 cilia and flagella associated protein 44 -0.0193144
EEA1 early endosome antigen 1 -0.0193109
CC2D1A coiled-coil and C2 domain containing 1A -0.0193079
APLP2 amyloid beta (A4) precursor-like protein 2 -0.0193045
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.019168
CLDN4 claudin 4 -0.0190752
R3HDM2 R3H domain containing 2 -0.0190476
NHSL1 NHS-like 1 -0.0189442
SPAG9 sperm associated antigen 9 -0.0189412
SHANK2 SH3 and multiple ankyrin repeat domains 2 -0.0188945
HELZ2 helicase with zinc finger 2, transcriptional coactivator -0.0188787
CHD4 chromodomain helicase DNA binding protein 4 -0.01879
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0187716
HIPK1 homeodomain interacting protein kinase 1 -0.0186965
BCL9L B-cell CLL/lymphoma 9-like -0.0186353
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -0.0185152
RPL35A ribosomal protein L35a -0.0185063
MIS18BP1 MIS18 binding protein 1 -0.0184664
MYO1B myosin IB -0.0184629
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0184539
H2AC6 H2A clustered histone 6 -0.0183238
TENT2 terminal nucleotidyltransferase 2 -0.0183146
FGF13 fibroblast growth factor 13 -0.0182916
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -0.0181631
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 -0.0180095
SETD2 SET domain containing 2 -0.0179439
ACTG1 actin gamma 1 -0.0178969
ERBB4 erb-b2 receptor tyrosine kinase 4 -0.0178877
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -0.0177753
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -0.0177743
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing -0.0176714
AKAP1 A kinase (PRKA) anchor protein 1 -0.0176263
RPS17 ribosomal protein S17 -0.0176228
PA2G4 proliferation-associated 2G4, 38kDa -0.0176159
LONP2 lon peptidase 2, peroxisomal -0.0176102
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed -0.017575
SMC4 structural maintenance of chromosomes 4 -0.0175728
MARCHF6 membrane associated ring-CH-type finger 6 -0.0175517
RPS19 ribosomal protein S19 -0.0175305
USP15 ubiquitin specific peptidase 15 -0.0173758
PTBP1 polypyrimidine tract binding protein 1 -0.0173608
RPS27 ribosomal protein S27 -0.0172982
CAND1 cullin-associated and neddylation-dissociated 1 -0.0172944
BCAS4 breast carcinoma amplified sequence 4 -0.0172851
RBM33 RNA binding motif protein 33 -0.017238
KPNB1 karyopherin (importin) beta 1 -0.0171701
C6ORF141 chromosome 6 open reading frame 141 -0.0171527
RPS29 ribosomal protein S29 -0.0171419
GDI2 GDP dissociation inhibitor 2 -0.0170943
ISG15 ISG15 ubiquitin-like modifier -0.0170828
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0170724
ATXN7L1 ataxin 7-like 1 -0.017068
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) -0.0170185
LMBR1 limb development membrane protein 1 -0.017017
THRB thyroid hormone receptor, beta -0.0170083
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -0.0169978
SMG5 SMG5 nonsense mediated mRNA decay factor -0.0168364
UBE2R2 ubiquitin-conjugating enzyme E2R 2 -0.0168334
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.0168041
TNPO2 transportin 2 -0.0167694
UTRN utrophin -0.0167502
WASF2 WAS protein family, member 2 -0.0167274
PFKL phosphofructokinase, liver -0.0167219
PFDN4 prefoldin subunit 4 -0.0166581
ALCAM activated leukocyte cell adhesion molecule -0.0166506
TLK2 tousled-like kinase 2 -0.0165717
ABR active BCR-related -0.0165217
TMEM260 transmembrane protein 260 -0.0164945
TOM1L2 target of myb1-like 2 (chicken) -0.0164566
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0164199
DNMBP dynamin binding protein -0.0164081
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) -0.0164074
MIPEP mitochondrial intermediate peptidase -0.0163984
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0163907
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0163695
MEGF9 multiple EGF-like-domains 9 -0.0162415
MBNL1 muscleblind-like splicing regulator 1 -0.0162393
PTGES2 prostaglandin E synthase 2 -0.016222
ZHX3 zinc fingers and homeoboxes 3 -0.0160918
PCSK6 proprotein convertase subtilisin/kexin type 6 -0.0160657
RTN4 reticulon 4 -0.0159587
ADPGK ADP-dependent glucokinase -0.0159435
TMEM18 transmembrane protein 18 -0.0159204
HIBADH 3-hydroxyisobutyrate dehydrogenase -0.0159148
FBXO42 F-box protein 42 -0.0157279
ITGB6 integrin, beta 6 -0.0157271
RPS4X ribosomal protein S4, X-linked -0.0157242
STARD13 StAR-related lipid transfer (START) domain containing 13 -0.0156922
GNA14 guanine nucleotide binding protein (G protein), alpha 14 -0.0156388
PHACTR2 phosphatase and actin regulator 2 -0.0156266
GALC galactosylceramidase -0.015593
FHIT fragile histidine triad -0.0155791
NUP205 nucleoporin 205kDa -0.0155626
TRAPPC12 trafficking protein particle complex 12 -0.0155609
NIPBL Nipped-B homolog (Drosophila) -0.0155201
RPS16 ribosomal protein S16 -0.0154786
TRIO trio Rho guanine nucleotide exchange factor -0.0154778
SRRM1 serine/arginine repetitive matrix 1 -0.015464
NFE2L1 nuclear factor, erythroid 2-like 1 -0.0153919
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta -0.0153622
CEP128 centrosomal protein 128kDa -0.0152906
MYO5C myosin VC -0.0152039
NME1 NME/NM23 nucleoside diphosphate kinase 1 -0.0151948
CDC42SE1 CDC42 small effector 1 -0.0151707
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 -0.0151602
LDLRAD3 low density lipoprotein receptor class A domain containing 3 -0.0151284
NRBP1 nuclear receptor binding protein 1 -0.0151114
SLX4IP SLX4 interacting protein -0.0150504
NUP62 nucleoporin 62kDa -0.015039
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0150047
AGO2 argonaute RISC catalytic component 2 -0.015003
MARK2 MAP/microtubule affinity-regulating kinase 2 -0.0149373
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -0.01492
H1-10 H1.10 linker histone -0.0149078
DYNC2I2 dynein 2 intermediate chain 2 -0.014885
AHCTF1 AT hook containing transcription factor 1 -0.014873
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.0148558
PLEKHA7 pleckstrin homology domain containing, family A member 7 -0.0148374
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0148051
ATP11C ATPase, class VI, type 11C -0.0147974
DLC1 DLC1 Rho GTPase activating protein -0.0147851
TK1 thymidine kinase 1, soluble -0.0147472
KIAA0586 KIAA0586 -0.014727
CMIP c-Maf inducing protein -0.0146914
NCOA6 nuclear receptor coactivator 6 -0.0146749
GPD1L glycerol-3-phosphate dehydrogenase 1-like -0.0146627
SLC25A43 solute carrier family 25, member 43 -0.0146324
RBM4 RNA binding motif protein 4 -0.0146295
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.0146004
KAT6B K(lysine) acetyltransferase 6B -0.0145987
KRT80 keratin 80, type II -0.0145773
SPOP speckle-type POZ protein -0.0145582
PARD3B par-3 family cell polarity regulator beta -0.0145301
SNX29 sorting nexin 29 -0.0145286
BICDL2 BICD family like cargo adaptor 2 -0.0144944
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 -0.0144347
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 -0.014415
UBE3C ubiquitin protein ligase E3C -0.0143965
SPIRE1 spire-type actin nucleation factor 1 -0.0143763
RPS14 ribosomal protein S14 -0.0143754
CDC14A cell division cycle 14A -0.0143704
CAMK1D calcium/calmodulin-dependent protein kinase ID -0.0143675
TSC22D1 TSC22 domain family, member 1 -0.0143339
DIAPH1 diaphanous-related formin 1 -0.0142981
RPLP0 ribosomal protein, large, P0 -0.0142871
RPS20 ribosomal protein S20 -0.0142851
EPHA7 EPH receptor A7 -0.0142623
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.0142519
PNISR PNN-interacting serine/arginine-rich protein -0.0142464
MASTL microtubule associated serine/threonine kinase-like -0.0142257
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.0142069
TSPAN31 tetraspanin 31 -0.014204
RRBP1 ribosome binding protein 1 -0.0141893
CLTA clathrin, light chain A -0.0141601
NAV1 neuron navigator 1 -0.0141474
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -0.0141359
TMEM164 transmembrane protein 164 -0.0141161
ARHGAP24 Rho GTPase activating protein 24 -0.0140496
AP2M1 adaptor-related protein complex 2, mu 1 subunit -0.0140331
CAMK2D calcium/calmodulin-dependent protein kinase II delta -0.0140212
EPB41L5 erythrocyte membrane protein band 4.1 like 5 -0.014018
CNOT6 CCR4-NOT transcription complex, subunit 6 -0.0140046
UBA6 ubiquitin-like modifier activating enzyme 6 -0.0139944
SF3B3 splicing factor 3b, subunit 3, 130kDa -0.0139923
MROH1 maestro heat-like repeat family member 1 -0.0139651
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0139475
FRMD5 FERM domain containing 5 -0.0139076
TBC1D22A TBC1 domain family, member 22A -0.0139006
CSNK1A1 casein kinase 1, alpha 1 -0.01384
ERBIN erbb2 interacting protein -0.0138358
MACF1 microtubule-actin crosslinking factor 1 -0.0137954
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 -0.0137676
PTPN14 protein tyrosine phosphatase, non-receptor type 14 -0.0137626
SERBP1 SERPINE1 mRNA binding protein 1 -0.0137525
KCNK6 potassium channel, two pore domain subfamily K, member 6 -0.0137243
KIF14 kinesin family member 14 -0.0137138
MYO16 myosin XVI -0.0137076
DYM dymeclin -0.0137004
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -0.0136475
MBTPS1 membrane-bound transcription factor peptidase, site 1 -0.0136394
ALMS1 Alstrom syndrome protein 1 -0.0135695
CENPP centromere protein P -0.0135646
ISOC1 isochorismatase domain containing 1 -0.0135614
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0135327
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0134684
TMLHE trimethyllysine hydroxylase, epsilon -0.0134425
THOC7 THO complex 7 -0.0134175
MB21D2 Mab-21 domain containing 2 -0.0133954
DCLK1 doublecortin-like kinase 1 -0.0133842
ENSA endosulfine alpha -0.0133763
TMSB4X thymosin beta 4, X-linked -0.0133757
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0133216
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 -0.0133177
LDLR low density lipoprotein receptor -0.013287
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.0132818
PRC1 protein regulator of cytokinesis 1 -0.0132768
ARHGAP21 Rho GTPase activating protein 21 -0.0132764
RC3H2 ring finger and CCCH-type domains 2 -0.0132434
SARS2 seryl-tRNA synthetase 2, mitochondrial -0.0132217
ZNF394 zinc finger protein 394 -0.0131841
BZW2 basic leucine zipper and W2 domains 2 -0.0131582
SCD5 stearoyl-CoA desaturase 5 -0.0131574
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) -0.0131226
MBD4 methyl-CpG binding domain protein 4 -0.0131162
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 -0.0131086
BMPR1A bone morphogenetic protein receptor, type IA -0.0131042
CLIC1 chloride intracellular channel 1 -0.0131032
USP9X ubiquitin specific peptidase 9, X-linked -0.0130998
SEPTIN7 septin 7 -0.0130566
GYS1 glycogen synthase 1 (muscle) -0.0130306
RAD21 RAD21 homolog (S. pombe) -0.0130223
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -0.0130176
PPP6R2 protein phosphatase 6, regulatory subunit 2 -0.0130003
NOL11 nucleolar protein 11 -0.0129711
FBXW8 F-box and WD repeat domain containing 8 -0.0129592
NF2 neurofibromin 2 (merlin) -0.0129566
STAG2 stromal antigen 2 -0.0129245
TPR translocated promoter region, nuclear basket protein -0.0129212
JUND jun D proto-oncogene -0.0129117
RYK receptor-like tyrosine kinase -0.0128996
FAM120B family with sequence similarity 120B -0.0128899
NIPAL2 NIPA-like domain containing 2 -0.0128621
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 -0.0128578
RPS3 ribosomal protein S3 -0.0128526
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -0.0128495
ZNF675 zinc finger protein 675 -0.0128379
PAPOLA poly(A) polymerase alpha -0.012784
CERCAM cerebral endothelial cell adhesion molecule -0.0127403
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0127271
THRAP3 thyroid hormone receptor associated protein 3 -0.012726
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -0.0127226
TCEAL4 transcription elongation factor A (SII)-like 4 -0.0127057
TPM3 tropomyosin 3 -0.0126888
NECTIN2 nectin cell adhesion molecule 2 -0.0126772
GNG5 guanine nucleotide binding protein (G protein), gamma 5 -0.0126416
MFSD8 major facilitator superfamily domain containing 8 -0.0126348
MYO19 myosin XIX -0.0126343
RDX radixin -0.0126292
MYO5A myosin VA (heavy chain 12, myoxin) -0.0126286
TTC3 tetratricopeptide repeat domain 3 -0.0126263
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 -0.0126109
DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21 -0.0126007
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -0.0125651
FAM177A1 family with sequence similarity 177, member A1 -0.0125601
USP25 ubiquitin specific peptidase 25 -0.0125375
CCDC47 coiled-coil domain containing 47 -0.0125316
TACC3 transforming, acidic coiled-coil containing protein 3 -0.012491
ZNF791 zinc finger protein 791 -0.0124909
SYNPO2 synaptopodin 2 -0.0124533
CROCC ciliary rootlet coiled-coil, rootletin -0.0124469
MXD1 MAX dimerization protein 1 -0.0124455
GCC2 GRIP and coiled-coil domain containing 2 -0.0124452
DPP3 dipeptidyl-peptidase 3 -0.0124358
OTULIN OTU deubiquitinase with linear linkage specificity -0.0124206
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -0.0123691
COPA coatomer protein complex, subunit alpha -0.0123619
RFWD3 ring finger and WD repeat domain 3 -0.0123501
SCRN1 secernin 1 -0.0123499
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.0123249
TMED8 transmembrane emp24 protein transport domain containing 8 -0.0122972
WASHC4 WASH complex subunit 4 -0.0122812
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) -0.0122564
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) -0.0122549
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 -0.0122257
NPEPPS aminopeptidase puromycin sensitive -0.0121832
POM121C POM121 transmembrane nucleoporin C -0.0121723
CLINT1 clathrin interactor 1 -0.0121584
CHD8 chromodomain helicase DNA binding protein 8 -0.0121504
XPOT exportin, tRNA -0.0121412
MEIS1 Meis homeobox 1 -0.0121254
POTEF POTE ankyrin domain family, member F -0.0121011
THOC2 THO complex 2 -0.01207
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) -0.0120631
ESR1 estrogen receptor 1 -0.0120253
UGCG UDP-glucose ceramide glucosyltransferase -0.0119787
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 -0.0119762
CTSA cathepsin A -0.0119731
TRAM1 translocation associated membrane protein 1 -0.0119329
MOB1A MOB kinase activator 1A -0.0119084
PPP1R12A protein phosphatase 1, regulatory subunit 12A -0.0118663
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 -0.0118562
INO80D INO80 complex subunit D -0.0118308
PCLO piccolo presynaptic cytomatrix protein -0.0118307
NIPSNAP1 nipsnap homolog 1 (C. elegans) -0.0117923
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -0.0117824
RPL35 ribosomal protein L35 -0.0117741
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle -0.0117543
BTN3A3 butyrophilin, subfamily 3, member A3 -0.0117517
MRPS25 mitochondrial ribosomal protein S25 -0.0117494
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) -0.0117349
CRABP2 cellular retinoic acid binding protein 2 -0.0117213
TACSTD2 tumor-associated calcium signal transducer 2 -0.0117121
FXYD3 FXYD domain containing ion transport regulator 3 -0.0117093
LAPTM4A lysosomal protein transmembrane 4 alpha -0.0117069
SLC38A10 solute carrier family 38, member 10 -0.0116844
NOLC1 nucleolar and coiled-body phosphoprotein 1 -0.0116725
PMP22 peripheral myelin protein 22 -0.0116652
NASP nuclear autoantigenic sperm protein (histone-binding) -0.0116564
CDT1 chromatin licensing and DNA replication factor 1 -0.0116363
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -0.0115952
HSBP1 heat shock factor binding protein 1 -0.0115906
FAM193B family with sequence similarity 193, member B -0.0115659
KMT5B lysine methyltransferase 5B -0.0115626
TFF3 trefoil factor 3 (intestinal) -0.0115532
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) -0.0115442
ENAH enabled homolog (Drosophila) -0.0115373
SEC23A Sec23 homolog A (S. cerevisiae) -0.011527
TOR1AIP2 torsin A interacting protein 2 -0.011516
KLF3 Kruppel-like factor 3 (basic) -0.0115016
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -0.0114978
BBS9 Bardet-Biedl syndrome 9 -0.0114846
SLC44A1 solute carrier family 44 (choline transporter), member 1 -0.0114725
YY1AP1 YY1 associated protein 1 -0.0114709
MRI1 methylthioribose-1-phosphate isomerase 1 -0.0114656
FOXK1 forkhead box K1 -0.0113918