MCF7_NVP-BSK805 2HCl_10µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description NVP-BSK805 2HCl 10µM perturbation in MCF7 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the MCF7_NVP-BSK805 2HCl_10µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.376661
BCAS3 breast carcinoma amplified sequence 3 0.315092
TFF1 trefoil factor 1 0.116613
DSCAM Down syndrome cell adhesion molecule 0.0932616
DSPP dentin sialophosphoprotein 0.0790798
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 0.0763214
LDLR low density lipoprotein receptor 0.0759981
TPM4 tropomyosin 4 0.0747722
MLPH melanophilin 0.0661401
MALRD1 MAM and LDL receptor class A domain containing 1 0.0625476
TPT1 tumor protein, translationally-controlled 1 0.0579033
RACK1 receptor for activated C kinase 1 0.0555089
BCAS4 breast carcinoma amplified sequence 4 0.0554736
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 0.055282
DHCR7 7-dehydrocholesterol reductase 0.0542899
DST dystonin 0.0538169
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0521001
SPTSSB serine palmitoyltransferase, small subunit B 0.0493364
EZR ezrin 0.0488297
FDPS farnesyl diphosphate synthase 0.0480322
DCDC2 doublecortin domain containing 2 0.046419
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.0456183
ALCAM activated leukocyte cell adhesion molecule 0.0422528
PBX1 pre-B-cell leukemia homeobox 1 0.0407975
PLXDC2 plexin domain containing 2 0.0399187
CLIC4 chloride intracellular channel 4 0.0398662
FOXO3 forkhead box O3 0.0396062
KAT6B K(lysine) acetyltransferase 6B 0.039291
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.0391903
DSTN destrin (actin depolymerizing factor) 0.0385548
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.0384171
NRP1 neuropilin 1 0.037983
TRPS1 trichorhinophalangeal syndrome I 0.0374103
TOB1 transducer of ERBB2, 1 0.0370646
IDI1 isopentenyl-diphosphate delta isomerase 1 0.0369606
FASN fatty acid synthase 0.0365493
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.0363061
KMT2C lysine (K)-specific methyltransferase 2C 0.0361481
TFF3 trefoil factor 3 (intestinal) 0.0357646
TRIM37 tripartite motif containing 37 0.0356193
MRPL13 mitochondrial ribosomal protein L13 0.0355559
LOC112694756 uncharaterized LOC112694756 0.0355256
AHNAK AHNAK nucleoprotein 0.0353634
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0351022
RPS3 ribosomal protein S3 0.0349705
CSDE1 cold shock domain containing E1, RNA-binding 0.032984
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.0328907
ENSA endosulfine alpha 0.0325907
EEF2 eukaryotic translation elongation factor 2 0.0325418
PLEC plectin 0.032311
RDX radixin 0.0322416
INSIG1 insulin induced gene 1 0.0319608
RPS6 ribosomal protein S6 0.0317837
GATA3 GATA binding protein 3 0.0311192
ADGRG6 adhesion G protein-coupled receptor G6 0.0310587
RPS18 ribosomal protein S18 0.0302559
MACC1 metastasis associated in colon cancer 1 0.0301064
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 0.0297261
ERBB3 erb-b2 receptor tyrosine kinase 3 0.0292201
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.029178
IRS1 insulin receptor substrate 1 0.028728
MYO1E myosin IE 0.0287021
RPL12 ribosomal protein L12 0.028379
VMP1 vacuole membrane protein 1 0.028354
SQSTM1 sequestosome 1 0.0282164
BASP1 brain abundant, membrane attached signal protein 1 0.0281646
RPS5 ribosomal protein S5 0.0279176
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.0278861
VCL vinculin 0.0277741
BCAS1 breast carcinoma amplified sequence 1 0.0276373
RPL37A ribosomal protein L37a 0.027548
TPM1 tropomyosin 1 (alpha) 0.0273714
RPS9 ribosomal protein S9 0.0269155
ABHD17C abhydrolase domain containing 17C 0.0269139
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.02686
EVL Enah/Vasp-like 0.0267228
PCED1B PC-esterase domain containing 1B 0.0265148
LMNA lamin A/C 0.0265138
RPLP1 ribosomal protein, large, P1 0.026359
ACTG1 actin gamma 1 0.0261663
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.0259565
KAZN kazrin, periplakin interacting protein 0.0259137
FTL ferritin, light polypeptide 0.0258449
PAWR PRKC, apoptosis, WT1, regulator 0.0257702
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.025136
SQLE squalene epoxidase 0.0250696
CEMIP2 cell migration inducing hyaluronidase 2 0.024915
H3-3B H3.3 histone B 0.0245154
RPS2 ribosomal protein S2 0.024481
PTPRF protein tyrosine phosphatase, receptor type, F 0.0244473
NAV1 neuron navigator 1 0.0239444
TM7SF2 transmembrane 7 superfamily member 2 0.0238673
MYADM myeloid-associated differentiation marker 0.0238659
MYOF myoferlin 0.0237655
IQGAP1 IQ motif containing GTPase activating protein 1 0.0236197
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.0235091
OSGIN2 oxidative stress induced growth inhibitor family member 2 0.0234441
ATRNL1 attractin-like 1 0.0234375
RPL13A ribosomal protein L13a 0.0233243
RPS11 ribosomal protein S11 0.0231193
CTSD cathepsin D 0.0230408
MYH9 myosin, heavy chain 9, non-muscle 0.0229692
LRP10 low density lipoprotein receptor-related protein 10 0.0229192
MAVS mitochondrial antiviral signaling protein 0.0227494
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.022727
IQCN IQ motif containing N 0.0225722
RPL10A ribosomal protein L10a 0.0224334
RPL7A ribosomal protein L7a 0.0221064
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0219819
NECTIN2 nectin cell adhesion molecule 2 0.021509
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.0214196
JUP junction plakoglobin 0.0214003
RPL29 ribosomal protein L29 0.0213353
DEPTOR DEP domain containing MTOR-interacting protein 0.0212537
LPIN1 lipin 1 0.0211994
S100A14 S100 calcium binding protein A14 0.021136
RPS23 ribosomal protein S23 0.0210391
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein 0.020926
RUNX1 runt-related transcription factor 1 0.0209229
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0208666
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 0.0206376
ACSL3 acyl-CoA synthetase long-chain family member 3 0.020555
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.0204902
MBNL1 muscleblind-like splicing regulator 1 0.0204409
BTBD9 BTB (POZ) domain containing 9 0.0204212
UBL4A ubiquitin-like 4A 0.0203687
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0201726
GNS glucosamine (N-acetyl)-6-sulfatase 0.0201682
LONRF2 LON peptidase N-terminal domain and ring finger 2 0.019756
ZNF148 zinc finger protein 148 0.0196377
MVD mevalonate (diphospho) decarboxylase 0.0196351
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 0.019395
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0192845
UNK unkempt family zinc finger 0.019248
PHACTR2 phosphatase and actin regulator 2 0.019184
ARL15 ADP-ribosylation factor-like 15 0.0191142
IRF2BPL interferon regulatory factor 2 binding protein-like 0.0190354
GLRA3 glycine receptor, alpha 3 0.0187857
MIDEAS mitotic deacetylase associated SANT domain protein 0.0187122
CTBP2 C-terminal binding protein 2 0.0185477
ARHGAP12 Rho GTPase activating protein 12 0.0185375
LGALS3 lectin, galactoside-binding, soluble, 3 0.0185193
USP32 ubiquitin specific peptidase 32 0.0184779
LRP1B low density lipoprotein receptor-related protein 1B 0.0184651
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.0183997
MUSK muscle, skeletal, receptor tyrosine kinase 0.0183744
FERMT2 fermitin family member 2 0.0182963
ABHD2 abhydrolase domain containing 2 0.0182591
SLC38A2 solute carrier family 38, member 2 0.0181949
SMIM14 small integral membrane protein 14 0.0181703
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 0.0181501
ZMYM5 zinc finger, MYM-type 5 0.0181358
LMBR1 limb development membrane protein 1 0.01813
ANXA2 annexin A2 0.018095
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 0.0179368
FREM2 FRAS1 related extracellular matrix protein 2 0.0179362
MGST1 microsomal glutathione S-transferase 1 0.0178264
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.0177109
USP9X ubiquitin specific peptidase 9, X-linked 0.0177053
EGR1 early growth response 1 0.0177022
RBM47 RNA binding motif protein 47 0.0176862
NCKAP5 NCK-associated protein 5 0.0176241
EEIG2 EEIG family member 2 0.0176029
TUFT1 tuftelin 1 0.0174455
CSRP1 cysteine and glycine-rich protein 1 0.0173928
RPLP0 ribosomal protein, large, P0 0.0173372
CPEB2 cytoplasmic polyadenylation element binding protein 2 0.0173338
APOD apolipoprotein D 0.0172657
SGMS1 sphingomyelin synthase 1 0.0172651
SAMD12 sterile alpha motif domain containing 12 0.0171678
LITAF lipopolysaccharide-induced TNF factor 0.0171624
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.0171164
HLA-E major histocompatibility complex, class I, E 0.0170846
WEE1 WEE1 G2 checkpoint kinase 0.0170348
RHOA ras homolog family member A 0.0169742
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.016969
INSR insulin receptor 0.0169026
BAG1 BCL2-associated athanogene 0.0168021
CD63 CD63 molecule 0.016736
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0166488
NALF1 NALCN channel auxiliary factor 1 0.0166098
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0165872
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.0165428
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.0165186
MYLIP myosin regulatory light chain interacting protein 0.0165081
RNF43 ring finger protein 43 0.0165011
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.0164698
CST3 cystatin C 0.0163881
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.0163695
DOCK5 dedicator of cytokinesis 5 0.0163651
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.0162841
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0162292
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.016188
SNX29 sorting nexin 29 0.0161794
PDLIM5 PDZ and LIM domain 5 0.0161699
NAV3 neuron navigator 3 0.0161347
QRICH1 glutamine-rich 1 0.0160495
CSNK1A1 casein kinase 1, alpha 1 0.0159854
ATOSA atos homolog A 0.0159315
KCNK6 potassium channel, two pore domain subfamily K, member 6 0.0159276
RAD23B RAD23 homolog B (S. cerevisiae) 0.015862
RPL15 ribosomal protein L15 0.0158514
FOXP1 forkhead box P1 0.0157846
CHD6 chromodomain helicase DNA binding protein 6 0.0157455
STAG2 stromal antigen 2 0.0157431
CCDC6 coiled-coil domain containing 6 0.015698
MYO16 myosin XVI 0.0156732
RPL27 ribosomal protein L27 0.0154788
SREBF2 sterol regulatory element binding transcription factor 2 0.0154257
ARSD arylsulfatase D 0.0152838
KLF6 Kruppel-like factor 6 0.0152825
MROH1 maestro heat-like repeat family member 1 0.0152721
LAMP2 lysosomal-associated membrane protein 2 0.0152264
SPINT1 serine peptidase inhibitor, Kunitz type 1 0.0152213
LMCD1 LIM and cysteine-rich domains 1 0.0152126
RPS8 ribosomal protein S8 0.015197
SH3D19 SH3 domain containing 19 0.0151955
CLIP1 CAP-GLY domain containing linker protein 1 0.0151747
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1 0.0151295
AMOTL2 angiomotin like 2 0.0151182
CCDC170 coiled-coil domain containing 170 0.0150059
TKT transketolase 0.0149969
SYNJ2BP synaptojanin 2 binding protein 0.0148919
JUN jun proto-oncogene 0.0147875
ACLY ATP citrate lyase 0.0147849
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.0147843
MTSS1 metastasis suppressor 1 0.0147631
FAM174B family with sequence similarity 174, member B 0.014682
CLDN4 claudin 4 0.0146778
ACYP2 acylphosphatase 2, muscle type 0.0146646
MIPEP mitochondrial intermediate peptidase 0.0145971
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.0145952
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.0145407
WDR6 WD repeat domain 6 0.0145042
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.0144852
C1QTNF6 C1q and tumor necrosis factor related protein 6 0.0143793
CAPN8 calpain 8 0.0143506
CLU clusterin 0.0143421
ARF4 ADP-ribosylation factor 4 0.0143089
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0142898
FAXDC2 fatty acid hydroxylase domain containing 2 0.0140823
EXOC6 exocyst complex component 6 0.014043
ESYT2 extended synaptotagmin-like protein 2 0.0140013
FGF13 fibroblast growth factor 13 0.0140009
CACUL1 CDK2-associated, cullin domain 1 0.0140005
RPL26 ribosomal protein L26 0.0139768
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.0139339
TBX2 T-box 2 0.0139086
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.013868
KDM5B lysine (K)-specific demethylase 5B 0.0138111
SYNGR2 synaptogyrin 2 0.0137354
SPOPL speckle-type POZ protein-like 0.0137066
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 0.0136884
SUCO SUN domain containing ossification factor 0.013652
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.0136415
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.0136262
OSBPL8 oxysterol binding protein-like 8 0.0135944
DENND4A DENN/MADD domain containing 4A 0.0135873
ERRFI1 ERBB receptor feedback inhibitor 1 0.0135766
TLE3 transducin-like enhancer of split 3 0.0135753
RPS16 ribosomal protein S16 0.0135453
RPS13 ribosomal protein S13 0.0134963
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.0134161
ITGB4 integrin, beta 4 0.0134134
UBC ubiquitin C 0.0133925
IQANK1 IQ motif and ankyrin repeat containing 1 0.0133642
SPNS1 spinster homolog 1 (Drosophila) 0.013355
TXNIP thioredoxin interacting protein 0.0133018
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 0.0132974
RPS19 ribosomal protein S19 0.0132829
RPS15 ribosomal protein S15 0.0132086
NEBL nebulette 0.0131972
CPEB4 cytoplasmic polyadenylation element binding protein 4 0.0131714
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 0.0131297
RPL31 ribosomal protein L31 0.0131193
TENM3 teneurin transmembrane protein 3 0.0130971
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.01305
TRAM1 translocation associated membrane protein 1 0.0129681
NOP53 NOP53 ribosome biogenesis factor 0.0129534
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 0.012934
RPS7 ribosomal protein S7 0.012908
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.0128866
RHPN2 rhophilin, Rho GTPase binding protein 2 0.0128623
EXT1 exostosin glycosyltransferase 1 0.0128424
PNRC1 proline-rich nuclear receptor coactivator 1 0.0128324
SPDEF SAM pointed domain containing ETS transcription factor 0.012817
GARRE1 granule associated Rac and RHOG effector 1 0.012806
MAML1 mastermind-like 1 (Drosophila) 0.0128051
DMXL1 Dmx-like 1 0.0127548
RPL23 ribosomal protein L23 0.0126792
TCEAL4 transcription elongation factor A (SII)-like 4 0.0126737
DTNA dystrobrevin, alpha 0.0126467
ZNF251 zinc finger protein 251 0.0126293
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0125649
PRSS8 protease, serine, 8 0.0125605
NAV2 neuron navigator 2 0.0125498
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 0.0125284
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0125013
OGA O-GlcNAcase 0.0124989
CDYL2 chromodomain protein, Y-like 2 0.0124408
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.0123755
AP3D1 adaptor-related protein complex 3, delta 1 subunit 0.0123083
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0122868
SPAG9 sperm associated antigen 9 0.0122754
FXYD3 FXYD domain containing ion transport regulator 3 0.0122441
HDAC8 histone deacetylase 8 0.0122022
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.0121876
NIPBL Nipped-B homolog (Drosophila) 0.0121711
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.0121698
MED13L mediator complex subunit 13-like 0.0121552
SIAH2 siah E3 ubiquitin protein ligase 2 0.0121547
NPTN neuroplastin 0.0121416
GIPC1 GIPC PDZ domain containing family, member 1 0.012111
PTPRG protein tyrosine phosphatase, receptor type, G 0.0120535
WWC3 WWC family member 3 0.0120307
PRKCH protein kinase C, eta 0.0120193
ETFA electron-transfer-flavoprotein, alpha polypeptide 0.0120096
TNRC6B trinucleotide repeat containing 6B 0.0119932
SETD1B SET domain containing 1B 0.0119567
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.0119562
PHF21A PHD finger protein 21A 0.0119558
C14ORF132 chromosome 14 open reading frame 132 0.011942
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 0.011909
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.0118537
IGF2R insulin-like growth factor 2 receptor 0.0118248
H4C8 H4 clustered histone 8 0.0118244
ANXA3 annexin A3 0.0118135
FOXN3 forkhead box N3 0.0118087
RPL39 ribosomal protein L39 0.0117796
NUMB numb homolog (Drosophila) 0.0117739
RBMX RNA binding motif protein, X-linked 0.0117653
KANTR KDM5C adjacent non-coding transcript 0.0117255
KLHL24 kelch-like family member 24 0.0117165
CLINT1 clathrin interactor 1 0.0117068
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) 0.0116908
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.0116893
IGSF1 immunoglobulin superfamily, member 1 0.0116417
TJP2 tight junction protein 2 0.0116345
ZNF704 zinc finger protein 704 0.011618
SERF2 small EDRK-rich factor 2 0.0116127
KIDINS220 kinase D-interacting substrate, 220kDa 0.0115791
RPS27 ribosomal protein S27 0.011579
WDR70 WD repeat domain 70 0.0115664
RAB2A RAB2A, member RAS oncogene family 0.0115657
KIAA1217 KIAA1217 0.0115083
RBMS1 RNA binding motif, single stranded interacting protein 1 0.0114912
PTPN14 protein tyrosine phosphatase, non-receptor type 14 0.0114777
N4BP2L2 NEDD4 binding protein 2-like 2 0.0114769
TRA2A transformer 2 alpha homolog (Drosophila) 0.0114685
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.0114569
UST uronyl-2-sulfotransferase 0.0114443
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 0.0114353
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 0.0114263
CCDC186 coiled-coil domain containing 186 0.0114209
ITPRID2 ITPR interacting domain containing 2 0.0114145
KIAA0513 KIAA0513 0.0113364
LIMA1 LIM domain and actin binding 1 0.0113336
KIAA0319L KIAA0319-like 0.0113327
RPL35A ribosomal protein L35a 0.0112464
THEM6 thioesterase superfamily member 6 0.0112398
H1-0 H1.0 linker histone 0.0112397
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 0.0112342
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.0112198
MGA MGA, MAX dimerization protein 0.0111995
SECISBP2 SECIS binding protein 2 0.0111761
FTH1 ferritin, heavy polypeptide 1 0.0110963
APLP2 amyloid beta (A4) precursor-like protein 2 0.0110886
JOSD2 Josephin domain containing 2 0.0110736
CRACD capping protein inhibiting regulator of actin dynamics 0.0110628
WDFY3 WD repeat and FYVE domain containing 3 0.0110462
NRCAM neuronal cell adhesion molecule 0.0110141
RPS4X ribosomal protein S4, X-linked 0.0109754
TACC2 transforming, acidic coiled-coil containing protein 2 0.0109306
FHIT fragile histidine triad 0.0109125
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0108984
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.0108556
DNAAF9 dynein axonemal assembly factor 9 0.0108291
RAB10 RAB10, member RAS oncogene family 0.0108124
ZXDC ZXD family zinc finger C 0.0108087
ARLN allregulin 0.0108078
CAPN9 calpain 9 0.0108067
NEO1 neogenin 1 0.0107994
MXD4 MAX dimerization protein 4 0.0107919
MORF4L1 mortality factor 4 like 1 0.0107493
SRSF5 serine/arginine-rich splicing factor 5 0.0107414
RNF149 ring finger protein 149 0.0107364
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 0.0107089
ARRDC1 arrestin domain containing 1 0.0106797
UTRN utrophin 0.0106587
HMGN1 high mobility group nucleosome binding domain 1 0.0106449
FBP1 fructose-1,6-bisphosphatase 1 0.0106293
XPC xeroderma pigmentosum, complementation group C 0.010558
CREBRF CREB3 regulatory factor 0.0105578
VRK2 vaccinia related kinase 2 0.0105137
RHOC ras homolog family member C 0.010507
MEIS1 Meis homeobox 1 0.0104902
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 0.0104874
PRKG1 protein kinase, cGMP-dependent, type I 0.0104719
GAB2 GRB2-associated binding protein 2 0.010467
SFTPA2 surfactant protein A2 0.0104614
USP15 ubiquitin specific peptidase 15 0.010397
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0103958
RPS27A ribosomal protein S27a 0.0103952
FAM177A1 family with sequence similarity 177, member A1 0.0103856
LTAP1 lipid transport auxiliary protein 1 0.0103597
RPSA ribosomal protein SA 0.0103441
RPL18 ribosomal protein L18 0.0103322
EIF5 eukaryotic translation initiation factor 5 0.01029
LCMT1 leucine carboxyl methyltransferase 1 0.0102577
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.0102254
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.0102189
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.0101927
TAOK3 TAO kinase 3 0.0101925
LAGE3 L antigen family, member 3 0.0101847
PCNP PEST proteolytic signal containing nuclear protein 0.0101805
CHKA choline kinase alpha 0.010164
CDK19 cyclin-dependent kinase 19 0.0101562
COL12A1 collagen, type XII, alpha 1 0.01012
RREB1 ras responsive element binding protein 1 0.010098
CALML5 calmodulin-like 5 0.0100857
KDM3A lysine (K)-specific demethylase 3A 0.0100853
PRUNE2 prune homolog 2 (Drosophila) 0.0100572
NHSL3 NHS like 3 0.0100561
H1-10 H1.10 linker histone 0.0100408
NPC1 Niemann-Pick disease, type C1 0.00999597
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 0.00998888
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 0.00997333
MEF2D myocyte enhancer factor 2D 0.0099576
DAPK3 death-associated protein kinase 3 0.00995262
REPS1 RALBP1 associated Eps domain containing 1 0.00994949
EPC2 enhancer of polycomb homolog 2 (Drosophila) 0.00994288
EPB41L5 erythrocyte membrane protein band 4.1 like 5 0.00993785
NR1D2 nuclear receptor subfamily 1, group D, member 2 0.00993159
DAND5 DAN domain family member 5, BMP antagonist 0.00990316
SLC71A2 solute carrier family 71 member 2 0.00989815
AAK1 AP2 associated kinase 1 0.00989075
TJP1 tight junction protein 1 0.00985881
UBE2H ubiquitin-conjugating enzyme E2H 0.00984262
ARMH4 armadillo like helical domain containing 4 0.00983886
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 0.00981659
UBE2B ubiquitin-conjugating enzyme E2B 0.00979759
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) 0.00977583
ZNF331 zinc finger protein 331 0.00975533
SCRN1 secernin 1 0.00975281
RNASET2 ribonuclease T2 0.00975265
MSMO1 methylsterol monooxygenase 1 0.00975171
NBPF1 neuroblastoma breakpoint family, member 1 0.00971073
SF3A1 splicing factor 3a, subunit 1, 120kDa 0.00967816
HIPK3 homeodomain interacting protein kinase 3 0.00966073
PTRH2 peptidyl-tRNA hydrolase 2 0.00965757
ODR4 odr-4 GPCR localization factor homolog 0.00965535
RPAP2 RNA polymerase II associated protein 2 0.00965233
XRN2 5'-3' exoribonuclease 2 0.0096428
ATP11C ATPase, class VI, type 11C 0.0096262
TSPAN12 tetraspanin 12 0.00960375
ANXA6 annexin A6 0.00956227
HNMT histamine N-methyltransferase 0.00955328
POGZ pogo transposable element with ZNF domain 0.00954602
TCF3 transcription factor 3 0.00953929
ZFC3H1 zinc finger, C3H1-type containing 0.00953081
REXO2 RNA exonuclease 2 0.00943944
SLC38A1 solute carrier family 38, member 1 0.00941154
WIPF1 WAS/WASL interacting protein family, member 1 0.00940734
ATP11B ATPase, class VI, type 11B 0.00940653
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit 0.00940396
BPTF bromodomain PHD finger transcription factor 0.00938108
SVIL supervillin 0.00937409
ITM2B integral membrane protein 2B 0.00936486
SNX30 sorting nexin family member 30 0.00934296
KMT5B lysine methyltransferase 5B 0.00934143
UBE3D ubiquitin protein ligase E3D 0.00934031
RPL5 ribosomal protein L5 0.00933985
KYNU kynureninase 0.00933491
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 0.00933365
UBA2 ubiquitin-like modifier activating enzyme 2 0.0093325
DUSP5 dual specificity phosphatase 5 0.00932177
PTMS parathymosin 0.00931468
RIOK3 RIO kinase 3 0.00930199
TUBGCP5 tubulin, gamma complex associated protein 5 0.00928388
TBC1D17 TBC1 domain family, member 17 0.00927403
STX7 syntaxin 7 0.00926294
N4BP2 NEDD4 binding protein 2 0.00924881
DDIT4 DNA-damage-inducible transcript 4 0.00923674
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.00922093
NHLRC3 NHL repeat containing 3 0.00918521
GTF2IRD2B GTF2I repeat domain containing 2B 0.00918345
RPL28 ribosomal protein L28 0.00917763
UXS1 UDP-glucuronate decarboxylase 1 0.00917045
BATF basic leucine zipper transcription factor, ATF-like 0.00915811
ELOVL6 ELOVL fatty acid elongase 6 0.00914866
ORC4 origin recognition complex, subunit 4 0.00914069
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 0.00913291
MAPK3 mitogen-activated protein kinase 3 0.00912328
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 0.00911717
ZNF248 zinc finger protein 248 0.00910467
MACROD1 MACRO domain containing 1 0.00909989
EPS15 epidermal growth factor receptor pathway substrate 15 0.00909437
BFAR bifunctional apoptosis regulator 0.00908437
HRNR hornerin 0.00908062
TTC17 tetratricopeptide repeat domain 17 0.00907399

decreased expression

Symbol Name Standardized Value
WWOX WW domain containing oxidoreductase -0.187596
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.178498
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.155354
ESR1 estrogen receptor 1 -0.125895
SULF2 sulfatase 2 -0.123399
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.103319
IGFBP5 insulin-like growth factor binding protein 5 -0.0826731
BMP7 bone morphogenetic protein 7 -0.0741429
IFI6 interferon, alpha-inducible protein 6 -0.0733077
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 -0.0725184
ATAD2 ATPase family, AAA domain containing 2 -0.0638275
THSD4 thrombospondin, type I, domain containing 4 -0.0636452
SMYD3 SET and MYND domain containing 3 -0.062822
PKM pyruvate kinase, muscle -0.0615502
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0593564
JARID2 jumonji, AT rich interactive domain 2 -0.0567566
ENO1 enolase 1, (alpha) -0.0564547
TUBD1 tubulin, delta 1 -0.056364
PACS1 phosphofurin acidic cluster sorting protein 1 -0.0546607
MAST4 microtubule associated serine/threonine kinase family member 4 -0.0539548
CCND1 cyclin D1 -0.0536287
AGR2 anterior gradient 2 -0.0531397
TUBA1B tubulin, alpha 1b -0.0523041
CNKSR3 CNKSR family member 3 -0.05204
GPC6 glypican 6 -0.0515613
RAD51B RAD51 paralog B -0.0498476
MACF1 microtubule-actin crosslinking factor 1 -0.0496404
MKI67 marker of proliferation Ki-67 -0.0492354
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) -0.0488599
TMEM64 transmembrane protein 64 -0.0469111
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.0466968
TRIM33 tripartite motif containing 33 -0.0466515
BIRC6 baculoviral IAP repeat containing 6 -0.0456693
HSPB1 heat shock 27kDa protein 1 -0.045486
UGDH UDP-glucose 6-dehydrogenase -0.0438457
TOM1L2 target of myb1-like 2 (chicken) -0.0431176
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0429964
PBX3 pre-B-cell leukemia homeobox 3 -0.0428588
TET2 tet methylcytosine dioxygenase 2 -0.042222
CENPP centromere protein P -0.0418542
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0405321
EMP2 epithelial membrane protein 2 -0.0398209
GRHL2 grainyhead-like 2 (Drosophila) -0.0392667
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.0382985
RHOBTB3 Rho-related BTB domain containing 3 -0.0375996
FAF1 Fas (TNFRSF6) associated factor 1 -0.0370293
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -0.0368991
PTK2 protein tyrosine kinase 2 -0.0367292
PRKCE protein kinase C, epsilon -0.0366029
ADCY1 adenylate cyclase 1 (brain) -0.0362508
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.0352919
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0350914
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0349381
CPA6 carboxypeptidase A6 -0.0341776
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.0341521
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0337793
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.0334287
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0332687
SIPA1L1 signal-induced proliferation-associated 1 like 1 -0.0330351
GSE1 Gse1 coiled-coil protein -0.0328776
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -0.0321726
NUP160 nucleoporin 160kDa -0.0313678
POTEF POTE ankyrin domain family, member F -0.0302141
RAB31 RAB31, member RAS oncogene family -0.030016
GNAS GNAS complex locus -0.0298043
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0296379
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 -0.0296072
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0292948
KDM2A lysine (K)-specific demethylase 2A -0.0291036
CKAP5 cytoskeleton associated protein 5 -0.0291025
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -0.0289439
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -0.0289124
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 -0.0289102
PICALM phosphatidylinositol binding clathrin assembly protein -0.0286637
GNA14 guanine nucleotide binding protein (G protein), alpha 14 -0.0286393
PDS5A PDS5 cohesin associated factor A -0.0286125
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.0277331
HIP1 huntingtin interacting protein 1 -0.0275949
PARD6B par-6 family cell polarity regulator beta -0.0275006
CCSER1 coiled-coil serine-rich protein 1 -0.0274543
PKP4 plakophilin 4 -0.0274183
ERBB4 erb-b2 receptor tyrosine kinase 4 -0.0269273
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0269073
TIAM1 T-cell lymphoma invasion and metastasis 1 -0.0267879
GREB1 growth regulation by estrogen in breast cancer 1 -0.0267425
BRCA1 breast cancer 1, early onset -0.0267194
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0264794
LDLRAD4 low density lipoprotein receptor class A domain containing 4 -0.0264697
SKA2 spindle and kinetochore associated complex subunit 2 -0.0261862
CHLSN cholesin -0.0259292
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -0.0259142
RANBP17 RAN binding protein 17 -0.0258019
TUBB tubulin, beta class I -0.0257264
TPD52L1 tumor protein D52-like 1 -0.0253409
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.0251451
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0251344
ATXN7L1 ataxin 7-like 1 -0.0250626
IGF1R insulin-like growth factor 1 receptor -0.0249865
PCDH7 protocadherin 7 -0.0248651
R3HDM1 R3H domain containing 1 -0.0247485
CAMKMT calmodulin-lysine N-methyltransferase -0.0245642
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -0.0245329
MED13 mediator complex subunit 13 -0.0241018
TRIO trio Rho guanine nucleotide exchange factor -0.0240054
TOP1 topoisomerase (DNA) I -0.0237655
DOCK1 dedicator of cytokinesis 1 -0.023758
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -0.0237571
PLXNA4 plexin A4 -0.0237406
SIDT1 SID1 transmembrane family, member 1 -0.0236939
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0234434
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0233049
DCAF7 DDB1 and CUL4 associated factor 7 -0.0232347
BMPR1A bone morphogenetic protein receptor, type IA -0.0231933
ATXN2 ataxin 2 -0.022981
TPI1 triosephosphate isomerase 1 -0.0228758
HIPK2 homeodomain interacting protein kinase 2 -0.0226447
SRSF4 serine/arginine-rich splicing factor 4 -0.0225713
PA2G4 proliferation-associated 2G4, 38kDa -0.0225052
PRRC2C proline-rich coiled-coil 2C -0.0224352
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0222016
ATG7 autophagy related 7 -0.0221235
ARID4A AT rich interactive domain 4A (RBP1-like) -0.0221024
TUBB4B tubulin, beta 4B class IVb -0.0220892
SBNO1 strawberry notch homolog 1 (Drosophila) -0.0220359
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 -0.022008
CA12 carbonic anhydrase XII -0.0218601
TASOR2 transcription activation suppressor family member 2 -0.0217238
ZFAND3 zinc finger, AN1-type domain 3 -0.0217229
PRKD2 protein kinase D2 -0.0216829
PCSK6 proprotein convertase subtilisin/kexin type 6 -0.0216471
KRT18 keratin 18, type I -0.021645
KPNB1 karyopherin (importin) beta 1 -0.0216347
THOC7 THO complex 7 -0.0216309
MTDH metadherin -0.0216204
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0215397
WWC1 WW and C2 domain containing 1 -0.0214612
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 -0.0214316
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0214025
FMN1 formin 1 -0.0212507
TRIP12 thyroid hormone receptor interactor 12 -0.0211013
HMGB1 high mobility group box 1 -0.0210373
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0209991
ECE1 endothelin converting enzyme 1 -0.0209335
BLTP2 bridge-like lipid transfer protein family member 2 -0.0209112
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.0208607
SYTL2 synaptotagmin-like 2 -0.0208501
NPAS3 neuronal PAS domain protein 3 -0.0208246
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0206759
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0205818
SLTM SAFB-like, transcription modulator -0.0205648
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) -0.0204831
UBE2Z ubiquitin-conjugating enzyme E2Z -0.0202788
PUM2 pumilio RNA-binding family member 2 -0.0202266
SPIDR scaffolding protein involved in DNA repair -0.0200727
RNF213 ring finger protein 213 -0.0200514
NUP155 nucleoporin 155kDa -0.0200397
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 -0.0200271
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -0.019971
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -0.0198942
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.0198257
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) -0.0197605
ZNF804B zinc finger protein 804B -0.0196504
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 -0.0195729
PRRC2B proline-rich coiled-coil 2B -0.0195183
MED12L mediator complex subunit 12-like -0.0194389
PRKCA protein kinase C, alpha -0.0194335
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.01939
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.0193687
PLEKHA7 pleckstrin homology domain containing, family A member 7 -0.0193287
INTS2 integrator complex subunit 2 -0.0191811
SAPCD2 suppressor APC domain containing 2 -0.0191646
MSI2 musashi RNA-binding protein 2 -0.0191564
CAPZB capping protein (actin filament) muscle Z-line, beta -0.0191146
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.0190723
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 -0.0190321
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0189643
RBL1 retinoblastoma-like 1 -0.018901
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.0187303
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) -0.0187265
R3HDM2 R3H domain containing 2 -0.0186929
PCNT pericentrin -0.0186701
ILF3 interleukin enhancer binding factor 3, 90kDa -0.0186557
RERG RAS-like, estrogen-regulated, growth inhibitor -0.0185821
CDK5RAP2 CDK5 regulatory subunit associated protein 2 -0.0185327
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.018474
PLK2 polo-like kinase 2 -0.0183532
SLC38A10 solute carrier family 38, member 10 -0.0182212
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.018211
RAD51C RAD51 paralog C -0.0181997
MBD5 methyl-CpG binding domain protein 5 -0.0181189
DCAF10 DDB1 and CUL4 associated factor 10 -0.0180446
DHDDS dehydrodolichyl diphosphate synthase -0.0180254
COPE coatomer protein complex, subunit epsilon -0.0180098
TP53 tumor protein p53 -0.0179471
GOLGA4 golgin A4 -0.017932
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 -0.0178301
APRT adenine phosphoribosyltransferase -0.0177537
MIS18BP1 MIS18 binding protein 1 -0.017667
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.0176642
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0176302
LIN54 lin-54 DREAM MuvB core complex component -0.0175859
SMC4 structural maintenance of chromosomes 4 -0.0175755
MSH2 mutS homolog 2 -0.0175709
TPR translocated promoter region, nuclear basket protein -0.0175487
FANCA Fanconi anemia, complementation group A -0.0174764
CMIP c-Maf inducing protein -0.0174347
PTBP3 polypyrimidine tract binding protein 3 -0.0173462
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -0.0173454
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -0.0172459
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0172453
CYBA cytochrome b-245, alpha polypeptide -0.0171876
GPR137C G protein-coupled receptor 137C -0.0171747
FCHSD2 FCH and double SH3 domains 2 -0.0169784
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.0169209
PPP6R3 protein phosphatase 6, regulatory subunit 3 -0.016896
FANCI Fanconi anemia, complementation group I -0.0168205
CD151 CD151 molecule (Raph blood group) -0.0167678
RPL35 ribosomal protein L35 -0.016753
STXBP5 syntaxin binding protein 5 (tomosyn) -0.0167347
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 -0.0166873
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.0166836
ALMS1 Alstrom syndrome protein 1 -0.0165874
S100A10 S100 calcium binding protein A10 -0.0165701
VAV2 vav 2 guanine nucleotide exchange factor -0.016501
WDHD1 WD repeat and HMG-box DNA binding protein 1 -0.0164802
SNRPA small nuclear ribonucleoprotein polypeptide A -0.0164195
XPO1 exportin 1 -0.0163708
CUL3 cullin 3 -0.0163596
SASH1 SAM and SH3 domain containing 1 -0.0163061
VAV3 vav 3 guanine nucleotide exchange factor -0.0162142
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0162111
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -0.0161976
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0161487
KCTD3 potassium channel tetramerization domain containing 3 -0.0161342
XPO7 exportin 7 -0.0161309
NECAB1 N-terminal EF-hand calcium binding protein 1 -0.0161146
CEP128 centrosomal protein 128kDa -0.0160069
C21ORF58 chromosome 21 open reading frame 58 -0.0160014
FUS FUS RNA binding protein -0.0159631
PUS7 pseudouridylate synthase 7 (putative) -0.0158929
CREBBP CREB binding protein -0.0158862
LUC7L LUC7-like (S. cerevisiae) -0.0158277
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 -0.0157645
PRR14L proline rich 14-like -0.0157641
EPHA6 EPH receptor A6 -0.0157583
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 -0.0157111
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.0156715
EP400 E1A binding protein p400 -0.0156234
ZFR zinc finger RNA binding protein -0.0156051
CALCR calcitonin receptor -0.0155904
SENP6 SUMO1/sentrin specific peptidase 6 -0.0155715
VCP valosin containing protein -0.0155666
PCBP3 poly(rC) binding protein 3 -0.0155634
ANKRD17 ankyrin repeat domain 17 -0.0155518
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) -0.015524
PHTF1 putative homeodomain transcription factor 1 -0.0155003
RAB30 RAB30, member RAS oncogene family -0.0154509
FLNA filamin A, alpha -0.0154213
KPNA6 karyopherin alpha 6 (importin alpha 7) -0.0153757
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 -0.0153666
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.0153268
CCAR1 cell division cycle and apoptosis regulator 1 -0.0152319
POLR1A polymerase (RNA) I polypeptide A, 194kDa -0.0152202
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -0.0151164
TRAP1 TNF receptor-associated protein 1 -0.0151027
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -0.0150376
CAMK1D calcium/calmodulin-dependent protein kinase ID -0.0150337
NUP107 nucleoporin 107kDa -0.0149609
SEPTIN11 septin 11 -0.0149001
UBR2 ubiquitin protein ligase E3 component n-recognin 2 -0.0148919
SCLT1 sodium channel and clathrin linker 1 -0.0148296
UBE3A ubiquitin protein ligase E3A -0.0148126
AFG2A AFG2 AAA ATPase homolog A -0.0148024
CAPN7 calpain 7 -0.0147715
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.0147593
NCAPG2 non-SMC condensin II complex, subunit G2 -0.0147552
FRMD5 FERM domain containing 5 -0.0147043
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase -0.0147001
GTF2IRD1 GTF2I repeat domain containing 1 -0.0147
RAB22A RAB22A, member RAS oncogene family -0.0146781
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -0.0146379
FNDC3B fibronectin type III domain containing 3B -0.0146358
OSBPL10 oxysterol binding protein-like 10 -0.0146341
CALR calreticulin -0.0146046
STK24 serine/threonine kinase 24 -0.014566
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta -0.0145415
ATP5MC1 ATP synthase membrane subunit c locus 1 -0.0145366
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa -0.0145269
GON4L gon-4-like (C. elegans) -0.014526
TRIM24 tripartite motif containing 24 -0.0145065
ZCCHC14 zinc finger, CCHC domain containing 14 -0.0144319
NUSAP1 nucleolar and spindle associated protein 1 -0.0144057
NFIB nuclear factor I/B -0.0143765
SF3B3 splicing factor 3b, subunit 3, 130kDa -0.0143542
NOTCH2 notch 2 -0.0143364
NUP153 nucleoporin 153kDa -0.0143318
ATF7IP2 activating transcription factor 7 interacting protein 2 -0.0143311
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -0.0143261
DIDO1 death inducer-obliterator 1 -0.0143163
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.0143125
KIF14 kinesin family member 14 -0.0142897
USP6NL USP6 N-terminal like -0.0142558
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.0142484
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.014243
CENPE centromere protein E, 312kDa -0.0141882
TICRR TOPBP1-interacting checkpoint and replication regulator -0.0141848
IFI27 interferon, alpha-inducible protein 27 -0.0141841
ATXN1 ataxin 1 -0.0141662
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 -0.0141533
RNF130 ring finger protein 130 -0.0141273
INO80 INO80 complex subunit -0.0140781
ARID1B AT rich interactive domain 1B (SWI1-like) -0.0140577
CENPF centromere protein F, 350/400kDa -0.0140531
FGF12 fibroblast growth factor 12 -0.0140315
KIF15 kinesin family member 15 -0.0140095
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 -0.0140062
RNF168 ring finger protein 168, E3 ubiquitin protein ligase -0.0139966
GLO1 glyoxalase I -0.0139453
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -0.0139208
SPATA13 spermatogenesis associated 13 -0.0139174
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -0.0139041
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -0.0138821
RPS17 ribosomal protein S17 -0.0138733
CMSS1 cms1 ribosomal small subunit homolog (yeast) -0.0138572
STRN3 striatin, calmodulin binding protein 3 -0.0138225
AP1G1 adaptor-related protein complex 1, gamma 1 subunit -0.013811
E2F3 E2F transcription factor 3 -0.0137669
XBP1 X-box binding protein 1 -0.0137527
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -0.0137389
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -0.0137194
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains -0.0137132
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) -0.0137072
CADPS2 Ca++-dependent secretion activator 2 -0.0136761
TMEM164 transmembrane protein 164 -0.0136596
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.013611
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 -0.0136085
PUM3 pumilio RNA binding family member 3 -0.0136027
CYRIB CYFIP related Rac1 interactor B -0.0135971
NTN1 netrin 1 -0.0135582
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 -0.0135003
C1ORF159 chromosome 1 open reading frame 159 -0.0134983
LTBP1 latent transforming growth factor beta binding protein 1 -0.0134914
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0134487
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -0.0134169
HSPH1 heat shock 105kDa/110kDa protein 1 -0.0134096
CHD8 chromodomain helicase DNA binding protein 8 -0.0134043
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -0.0133985
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 -0.0133298
SLMAP sarcolemma associated protein -0.0133294
FBXO11 F-box protein 11 -0.0132958
ATXN7 ataxin 7 -0.0132529
GMDS GDP-mannose 4,6-dehydratase -0.0132363
MCU mitochondrial calcium uniporter -0.0131974
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -0.0131402
EFNA5 ephrin-A5 -0.0130952
PTPRA protein tyrosine phosphatase, receptor type, A -0.0130911
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 -0.0130878
CRTC3 CREB regulated transcription coactivator 3 -0.0130601
PTPRS protein tyrosine phosphatase, receptor type, S -0.0130351
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 -0.0130211
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0130105
PXDN peroxidasin -0.0129873
IFNAR1 interferon (alpha, beta and omega) receptor 1 -0.0129568
TOP6BL TOP6B like initiator of meiotic double strand breaks -0.0129092
ZMYM2 zinc finger, MYM-type 2 -0.0129066
XPR1 xenotropic and polytropic retrovirus receptor 1 -0.0128964
CD24 CD24 molecule -0.0128854
LGALS12 lectin, galactoside-binding, soluble, 12 -0.0128793
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 -0.0128766
CEP350 centrosomal protein 350kDa -0.012828
BICDL1 BICD family like cargo adaptor 1 -0.0128259
STIL SCL/TAL1 interrupting locus -0.0128041
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -0.012767
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 -0.0127534
NIBAN2 niban apoptosis regulator 2 -0.0126389
MPHOSPH9 M-phase phosphoprotein 9 -0.0126292
CD58 CD58 molecule -0.0126284
KIAA1671 KIAA1671 -0.0126117
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -0.0126002
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.0125966
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) -0.0125941
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0125826
PATJ PATJ crumbs cell polarity complex component -0.0125627
TCF12 transcription factor 12 -0.0125523
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 -0.0124823
NXN nucleoredoxin -0.0124619
CAMK2G calcium/calmodulin-dependent protein kinase II gamma -0.0124528
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha -0.0124441
ZMYM4 zinc finger, MYM-type 4 -0.0124433
KNL1 kinetochore scaffold 1 -0.0123882
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed -0.0123307
UIMC1 ubiquitin interaction motif containing 1 -0.0123054
KIF20B kinesin family member 20B -0.0122882
ADAR adenosine deaminase, RNA-specific -0.0122856
TOM1L1 target of myb1 (chicken)-like 1 -0.0122822
PRIM2 primase, DNA, polypeptide 2 (58kDa) -0.012268
PRSS23 protease, serine, 23 -0.0122347
CCDC88C coiled-coil domain containing 88C -0.0122246
PTPN1 protein tyrosine phosphatase, non-receptor type 1 -0.0122177
DENR density-regulated protein -0.0122159
SAMD1 sterile alpha motif domain containing 1 -0.0121961
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0121906
RC3H2 ring finger and CCCH-type domains 2 -0.0121885
LARP1 La ribonucleoprotein domain family, member 1 -0.0121726
ANKRD26 ankyrin repeat domain 26 -0.0121698
GPATCH8 G patch domain containing 8 -0.0121539
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.0121098
CBR4 carbonyl reductase 4 -0.0121055
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.0120794
ARTN artemin -0.0120652
RARS1 arginyl-tRNA synthetase 1 -0.0120146
AMZ1 archaelysin family metallopeptidase 1 -0.0119738
NF1 neurofibromin 1 -0.0119456
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -0.0119269
BRCA2 breast cancer 2, early onset -0.0119166
ZMYND11 zinc finger, MYND-type containing 11 -0.0118997
LDLRAD3 low density lipoprotein receptor class A domain containing 3 -0.0118838
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -0.0118287
CLTC clathrin, heavy chain (Hc) -0.0117925
GPBP1 GC-rich promoter binding protein 1 -0.0117651
RCOR1 REST corepressor 1 -0.0117568
KLHL22 kelch-like family member 22 -0.0117171
SPG11 spastic paraplegia 11 (autosomal recessive) -0.0117122
MDN1 MDN1, midasin homolog (yeast) -0.01171
EPN2 epsin 2 -0.011696
PRKCI protein kinase C, iota -0.011672
IQCB1 IQ motif containing B1 -0.0116697
NT5C2 5'-nucleotidase, cytosolic II -0.0116675
MYO9B myosin IXB -0.0116617
MMS22L MMS22-like, DNA repair protein -0.0116574
PHC3 polyhomeotic homolog 3 (Drosophila) -0.0116086
AUTS2 autism susceptibility candidate 2 -0.0115993
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) -0.0115756
RPTOR regulatory associated protein of MTOR, complex 1 -0.0115724
MSH3 mutS homolog 3 -0.0115608
ZDHHC20 zinc finger, DHHC-type containing 20 -0.0115557
CHD1L chromodomain helicase DNA binding protein 1-like -0.0115398
NTAQ1 N-terminal glutamine amidase 1 -0.0115212
TPX2 TPX2, microtubule-associated -0.0114688
TAGLN2 transgelin 2 -0.0114687
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0114428
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -0.0114313
WDR82 WD repeat domain 82 -0.0114181
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 -0.0114172
SCAF8 SR-related CTD-associated factor 8 -0.0114169
XPO4 exportin 4 -0.0114129
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -0.0113985
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) -0.0113843
MASTL microtubule associated serine/threonine kinase-like -0.0113665
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.0113139
RBPMS RNA binding protein with multiple splicing -0.0113139
UBE2K ubiquitin-conjugating enzyme E2K -0.0112998
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -0.0112906
CNOT2 CCR4-NOT transcription complex, subunit 2 -0.0112881
CHEK2 checkpoint kinase 2 -0.0112393
PPP1R12B protein phosphatase 1, regulatory subunit 12B -0.0112302
DNM2 dynamin 2 -0.0111983
RILPL1 Rab interacting lysosomal protein-like 1 -0.0111669
DGKH diacylglycerol kinase, eta -0.011164
CXXC5 CXXC finger protein 5 -0.0111486
BTBD7 BTB (POZ) domain containing 7 -0.0111424
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit -0.011138
RRP1B ribosomal RNA processing 1B -0.0111311
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 -0.0111255
IP6K2 inositol hexakisphosphate kinase 2 -0.0111231
KTN1 kinectin 1 (kinesin receptor) -0.0111073
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit -0.0110972
ENOX2 ecto-NOX disulfide-thiol exchanger 2 -0.0110855
PRC1 protein regulator of cytokinesis 1 -0.0110739
GAPVD1 GTPase activating protein and VPS9 domains 1 -0.0110647
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 -0.0110456
PDXK pyridoxal (pyridoxine, vitamin B6) kinase -0.0110388
PDIA3 protein disulfide isomerase family A, member 3 -0.0110385
NIPAL2 NIPA-like domain containing 2 -0.0110352
HELZ helicase with zinc finger -0.0110245
RPS12 ribosomal protein S12 -0.0109517
FUCA2 fucosidase, alpha-L- 2, plasma -0.0109403
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -0.0109394
ASF1B anti-silencing function 1B histone chaperone -0.0109378
SLC39A11 solute carrier family 39, member 11 -0.0109179
TUFM Tu translation elongation factor, mitochondrial -0.0108913
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -0.0108813
TXN2 thioredoxin 2 -0.0108803
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.0108712
DCAF5 DDB1 and CUL4 associated factor 5 -0.010865
ZC3H18 zinc finger CCCH-type containing 18 -0.010827
NEK1 NIMA-related kinase 1 -0.0108217
AHCTF1 AT hook containing transcription factor 1 -0.0108049
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.0107993
BRD4 bromodomain containing 4 -0.0107833
SMIM44 small integral membrane protein 44 -0.0107726
SIN3A SIN3 transcription regulator family member A -0.0107581
ARID1A AT rich interactive domain 1A (SWI-like) -0.0107466
DENND1A DENN/MADD domain containing 1A -0.0107428
SIPA1L2 signal-induced proliferation-associated 1 like 2 -0.0107361
STK4 serine/threonine kinase 4 -0.0106692
FOXJ3 forkhead box J3 -0.0106499
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.0106355
MRTFB myocardin related transcription factor B -0.0106275
UBTF upstream binding transcription factor, RNA polymerase I -0.0106255