MCF7_NVP-BSK805 2HCl_100nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description NVP-BSK805 2HCl 100nM perturbation in MCF7 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the MCF7_NVP-BSK805 2HCl_100nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
EVL Enah/Vasp-like 0.104934
MRPL13 mitochondrial ribosomal protein L13 0.0976217
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.0951057
DSPP dentin sialophosphoprotein 0.0869357
SLC38A1 solute carrier family 38, member 1 0.0865028
TPM4 tropomyosin 4 0.0805108
RPL15 ribosomal protein L15 0.0751242
CALR calreticulin 0.073374
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.071521
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0679197
RPL37 ribosomal protein L37 0.067533
RPL30 ribosomal protein L30 0.0675243
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0655144
VMP1 vacuole membrane protein 1 0.0624144
RPS2 ribosomal protein S2 0.0608899
KRT19 keratin 19, type I 0.0564622
TTC3 tetratricopeptide repeat domain 3 0.0557255
KRT8 keratin 8, type II 0.0548123
FLNA filamin A, alpha 0.0544306
ALCAM activated leukocyte cell adhesion molecule 0.0542483
PAN3 PAN3 poly(A) specific ribonuclease subunit 0.0541641
RPL13A ribosomal protein L13a 0.0521012
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.0515622
RPS17 ribosomal protein S17 0.0505489
PARD6B par-6 family cell polarity regulator beta 0.0504964
JAK1 Janus kinase 1 0.0504603
RPL23A ribosomal protein L23a 0.0501046
RPS21 ribosomal protein S21 0.0499819
RPL37A ribosomal protein L37a 0.0499473
IGFBP5 insulin-like growth factor binding protein 5 0.0497651
RPS6 ribosomal protein S6 0.0495563
RAB10 RAB10, member RAS oncogene family 0.04934
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.0493239
UBE2H ubiquitin-conjugating enzyme E2H 0.0491892
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0486479
RHPN2 rhophilin, Rho GTPase binding protein 2 0.0478836
TOB1 transducer of ERBB2, 1 0.0474427
NRIP1 nuclear receptor interacting protein 1 0.0470897
LMNA lamin A/C 0.045992
ACTG1 actin gamma 1 0.0458814
PAWR PRKC, apoptosis, WT1, regulator 0.0458137
CCND1 cyclin D1 0.045461
RPS29 ribosomal protein S29 0.0451076
PBX1 pre-B-cell leukemia homeobox 1 0.0449181
PPDPF pancreatic progenitor cell differentiation and proliferation factor 0.0446656
RPL11 ribosomal protein L11 0.0442037
H3-3B H3.3 histone B 0.0436505
RPS19 ribosomal protein S19 0.0433836
RPL12 ribosomal protein L12 0.04323
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0423391
LARP1 La ribonucleoprotein domain family, member 1 0.0422084
ENO1 enolase 1, (alpha) 0.0420242
ABHD2 abhydrolase domain containing 2 0.0418424
PACS1 phosphofurin acidic cluster sorting protein 1 0.041649
DSTN destrin (actin depolymerizing factor) 0.0411317
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 0.0405288
HRNR hornerin 0.03933
RPLP1 ribosomal protein, large, P1 0.0392417
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.0392351
RPS8 ribosomal protein S8 0.0389625
SETD2 SET domain containing 2 0.0384835
GNAS GNAS complex locus 0.0382276
NEBL nebulette 0.0379068
TMEM150C transmembrane protein 150C 0.0378062
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.0377062
RPL35A ribosomal protein L35a 0.0375145
FTH1 ferritin, heavy polypeptide 1 0.0370435
UBL4A ubiquitin-like 4A 0.0369434
RPS3 ribosomal protein S3 0.0366983
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.0366182
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 0.0362915
RPL18 ribosomal protein L18 0.0359255
REST RE1-silencing transcription factor 0.0355937
CYRIB CYFIP related Rac1 interactor B 0.0354694
CXXC5 CXXC finger protein 5 0.0353935
COL4A5 collagen, type IV, alpha 5 0.0351102
BMP7 bone morphogenetic protein 7 0.0344218
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.0342567
SEPTIN9 septin 9 0.0342148
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0341701
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.0338372
SH3D19 SH3 domain containing 19 0.0336887
NCAM2 neural cell adhesion molecule 2 0.033547
SACK1B scaffolding CK1 anchoring protein B 0.0334666
RPL18A ribosomal protein L18a 0.033253
AHNAK AHNAK nucleoprotein 0.0331525
MYO1E myosin IE 0.0326083
ARID4B AT rich interactive domain 4B (RBP1-like) 0.0325284
ARTN artemin 0.0323447
TAOK3 TAO kinase 3 0.0322915
MYOF myoferlin 0.0322749
RPSA ribosomal protein SA 0.0322165
PLXDC2 plexin domain containing 2 0.0321128
LITAF lipopolysaccharide-induced TNF factor 0.0319101
TMEM87A transmembrane protein 87A 0.0318915
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.0318774
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.0316368
SPIDR scaffolding protein involved in DNA repair 0.0315586
CSRP1 cysteine and glycine-rich protein 1 0.0312967
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0308262
CLTB clathrin, light chain B 0.0306235
RPS12 ribosomal protein S12 0.0305883
CTBP2 C-terminal binding protein 2 0.0305587
RPL10A ribosomal protein L10a 0.0305394
ZNF217 zinc finger protein 217 0.0303863
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0303248
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.0301655
ZFP36L2 ZFP36 ring finger protein-like 2 0.0300575
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0299977
DLG5 discs, large homolog 5 (Drosophila) 0.0295856
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.0295255
RPL7A ribosomal protein L7a 0.0293956
FGF12 fibroblast growth factor 12 0.029233
RPS5 ribosomal protein S5 0.0290327
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.0288884
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.0288415
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 0.0288128
APOD apolipoprotein D 0.0286146
IP6K1 inositol hexakisphosphate kinase 1 0.0285397
SMIM14 small integral membrane protein 14 0.0282053
SERBP1 SERPINE1 mRNA binding protein 1 0.0281335
APP amyloid beta (A4) precursor protein 0.0278739
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.0277128
SOX4 SRY (sex determining region Y)-box 4 0.0276516
CLDN4 claudin 4 0.0274701
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) 0.027379
RPS4X ribosomal protein S4, X-linked 0.0273754
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0270797
AOPEP aminopeptidase O (putative) 0.0270282
RNF149 ring finger protein 149 0.0270115
TBX2 T-box 2 0.0268772
RSL1D1 ribosomal L1 domain containing 1 0.0268364
MORF4L2 mortality factor 4 like 2 0.0268175
AFAP1 actin filament associated protein 1 0.0264981
ABI2 abl-interactor 2 0.0264508
ANKRD17 ankyrin repeat domain 17 0.0264218
PDLIM5 PDZ and LIM domain 5 0.0263939
ELP2 elongator acetyltransferase complex subunit 2 0.0262672
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.026163
TLK2 tousled-like kinase 2 0.0260089
BCL2 B-cell CLL/lymphoma 2 0.0259666
CLTC clathrin, heavy chain (Hc) 0.0256514
TBC1D5 TBC1 domain family, member 5 0.0256466
TSC22D2 TSC22 domain family, member 2 0.0256133
SNX14 sorting nexin 14 0.0255836
EPB41L5 erythrocyte membrane protein band 4.1 like 5 0.0254662
SHROOM3 shroom family member 3 0.0253519
LRP10 low density lipoprotein receptor-related protein 10 0.0253482
AFTPH aftiphilin 0.0251309
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.0250942
S100A10 S100 calcium binding protein A10 0.025065
RACK1 receptor for activated C kinase 1 0.0250019
RPL14 ribosomal protein L14 0.024989
SQSTM1 sequestosome 1 0.0249101
WIPF1 WAS/WASL interacting protein family, member 1 0.024874
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.0248223
MACC1 metastasis associated in colon cancer 1 0.0246735
LOC102724023 ES1 protein homolog, mitochondrial 0.0246714
SET SET nuclear proto-oncogene 0.0244203
GOLGA8B golgin A8 family, member B 0.0243968
ESYT2 extended synaptotagmin-like protein 2 0.0243617
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.0239846
RPS20 ribosomal protein S20 0.023932
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.0239096
MAP3K9 mitogen-activated protein kinase kinase kinase 9 0.0239013
RPL32 ribosomal protein L32 0.0238885
RPLP0 ribosomal protein, large, P0 0.0238426
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0238351
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.0237897
MAP4 microtubule-associated protein 4 0.0237812
MYO5A myosin VA (heavy chain 12, myoxin) 0.0237721
ARID1B AT rich interactive domain 1B (SWI1-like) 0.023609
ZFR zinc finger RNA binding protein 0.0235311
LGALS3 lectin, galactoside-binding, soluble, 3 0.0233743
CDV3 CDV3 homolog (mouse) 0.023337
CD81 CD81 molecule 0.0232587
GFPT1 glutamine--fructose-6-phosphate transaminase 1 0.0232037
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 0.0231818
NONO non-POU domain containing, octamer-binding 0.0231308
EGR1 early growth response 1 0.0229899
ATOSA atos homolog A 0.0229575
MYO6 myosin VI 0.0229474
JMY junction mediating and regulatory protein, p53 cofactor 0.0228787
VGLL4 vestigial-like family member 4 0.0228298
SF3B4 splicing factor 3b, subunit 4, 49kDa 0.022793
RNF169 ring finger protein 169 0.0227626
ITFG1 integrin alpha FG-GAP repeat containing 1 0.0225331
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.0223905
PATJ PATJ crumbs cell polarity complex component 0.0223457
MYH9 myosin, heavy chain 9, non-muscle 0.0223141
IQGAP1 IQ motif containing GTPase activating protein 1 0.0222805
RPL7 ribosomal protein L7 0.0222189
RPS27 ribosomal protein S27 0.022151
LARP4 La ribonucleoprotein domain family, member 4 0.0220691
VCL vinculin 0.0219862
FERMT2 fermitin family member 2 0.0219766
HDLBP high density lipoprotein binding protein 0.021898
SMAD3 SMAD family member 3 0.02189
NT5C3A 5'-nucleotidase, cytosolic IIIA 0.0218626
RPL27 ribosomal protein L27 0.0218508
RHOA ras homolog family member A 0.0218331
FOXO3 forkhead box O3 0.0217811
FGD4 FYVE, RhoGEF and PH domain containing 4 0.021705
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.0216468
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.0215726
NCKAP5 NCK-associated protein 5 0.0215149
PRICKLE2 prickle homolog 2 (Drosophila) 0.0215139
RPL8 ribosomal protein L8 0.0214782
SLC4A2 solute carrier family 4 (anion exchanger), member 2 0.0214203
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.0213863
RPS28 ribosomal protein S28 0.021383
PRRC2C proline-rich coiled-coil 2C 0.021339
RPL28 ribosomal protein L28 0.0213266
HMGN1 high mobility group nucleosome binding domain 1 0.0213197
PTPN14 protein tyrosine phosphatase, non-receptor type 14 0.0212366
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) 0.0211951
FXYD3 FXYD domain containing ion transport regulator 3 0.0211685
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.0211261
RPS14 ribosomal protein S14 0.0211106
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 0.0210935
PERP PERP, TP53 apoptosis effector 0.02099
IRS1 insulin receptor substrate 1 0.0209379
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 0.0209205
CLMB calcimembrin 0.0208504
OGFR opioid growth factor receptor 0.0208089
RPL31 ribosomal protein L31 0.0207798
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 0.0207367
SYNRG synergin, gamma 0.0207166
DPP7 dipeptidyl-peptidase 7 0.0207086
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 0.0206629
ITGB4 integrin, beta 4 0.0206533
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.020606
MRPL41 mitochondrial ribosomal protein L41 0.0205425
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 0.0205424
NUMA1 nuclear mitotic apparatus protein 1 0.0204694
CLOCK clock circadian regulator 0.0204558
LPIN2 lipin 2 0.0204537
DEGS2 delta(4)-desaturase, sphingolipid 2 0.0204167
NPTN neuroplastin 0.020252
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.0202456
PLEKHA6 pleckstrin homology domain containing, family A member 6 0.0201775
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0201447
BASP1 brain abundant, membrane attached signal protein 1 0.0201345
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.0200504
TRPS1 trichorhinophalangeal syndrome I 0.0200422
ATP5F1E ATP synthase F1 subunit epsilon 0.0200133
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.0199922
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.0199271
RBM23 RNA binding motif protein 23 0.0198891
ATXN7 ataxin 7 0.019858
MSH2 mutS homolog 2 0.0197569
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 0.0197562
RPS23 ribosomal protein S23 0.0197487
PHACTR2 phosphatase and actin regulator 2 0.0197474
SSR1 signal sequence receptor, alpha 0.0197429
FOXK1 forkhead box K1 0.0196075
PTPRA protein tyrosine phosphatase, receptor type, A 0.019564
TIAM1 T-cell lymphoma invasion and metastasis 1 0.0195611
RPS7 ribosomal protein S7 0.0194906
TUG1 taurine up-regulated 1 (non-protein coding) 0.0194739
CLIP1 CAP-GLY domain containing linker protein 1 0.0194017
PXDN peroxidasin 0.0193969
STC2 stanniocalcin 2 0.019394
SMIM44 small integral membrane protein 44 0.0193743
FLOT2 flotillin 2 0.0193282
KIF11 kinesin family member 11 0.0192604
CSDE1 cold shock domain containing E1, RNA-binding 0.0192521
RAD23B RAD23 homolog B (S. cerevisiae) 0.0192384
ZDHHC20 zinc finger, DHHC-type containing 20 0.0192043
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.0191862
RPS27A ribosomal protein S27a 0.0191668
MFSD6 major facilitator superfamily domain containing 6 0.019136
RAP1B RAP1B, member of RAS oncogene family 0.0191288
BCAS2 breast carcinoma amplified sequence 2 0.0190909
USP48 ubiquitin specific peptidase 48 0.0190736
KLHDC10 kelch domain containing 10 0.0190446
HEATR6 HEAT repeat containing 6 0.0190103
KLF6 Kruppel-like factor 6 0.0189458
TTC17 tetratricopeptide repeat domain 17 0.0189451
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 0.0189172
HNRNPF heterogeneous nuclear ribonucleoprotein F 0.0189087
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0189085
GPC6 glypican 6 0.0188962
RPL34 ribosomal protein L34 0.0187829
ATRNL1 attractin-like 1 0.0187804
RRP1B ribosomal RNA processing 1B 0.0187412
RPL4 ribosomal protein L4 0.0187388
TTF1 transcription termination factor, RNA polymerase I 0.0186686
PCBP2 poly(rC) binding protein 2 0.0186556
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 0.0186544
INSR insulin receptor 0.0186419
EP300 E1A binding protein p300 0.0186089
TUFT1 tuftelin 1 0.0185843
LAPTM4A lysosomal protein transmembrane 4 alpha 0.018584
SH3GLB2 SH3-domain GRB2-like endophilin B2 0.0185372
XPO6 exportin 6 0.0184825
PISD phosphatidylserine decarboxylase 0.018435
GOLM2 golgi membrane protein 2 0.0184177
CD151 CD151 molecule (Raph blood group) 0.0184037
ZNF644 zinc finger protein 644 0.0183596
GRID1 glutamate receptor, ionotropic, delta 1 0.0183595
RPL5 ribosomal protein L5 0.0183434
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 0.0183124
PRR11 proline rich 11 0.0182921
GSPT1 G1 to S phase transition 1 0.0182543
CNOT10 CCR4-NOT transcription complex, subunit 10 0.018222
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.0182109
FBXO11 F-box protein 11 0.0181833
GSN gelsolin 0.0181747
COX5B cytochrome c oxidase subunit Vb 0.0181605
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 0.0181457
UBE2B ubiquitin-conjugating enzyme E2B 0.0181143
RIMS2 regulating synaptic membrane exocytosis 2 0.018095
SLC44A1 solute carrier family 44 (choline transporter), member 1 0.018092
SOS2 son of sevenless homolog 2 (Drosophila) 0.0180598
LEPROT leptin receptor overlapping transcript 0.0179843
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 0.0179716
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.017956
IER2 immediate early response 2 0.0179468
OAZ1 ornithine decarboxylase antizyme 1 0.0179078
PRDX2 peroxiredoxin 2 0.0178836
FUBP3 far upstream element (FUSE) binding protein 3 0.0178801
RRBP1 ribosome binding protein 1 0.017856
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0178278
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) 0.0178254
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.0178197
PER2 period circadian clock 2 0.0178183
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.0177996
OSBPL8 oxysterol binding protein-like 8 0.0177889
MBOAT1 membrane bound O-acyltransferase domain containing 1 0.0177691
TMEM41A transmembrane protein 41A 0.0177685
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.0177083
MACO1 macoilin 1 0.0177025
MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.0176888
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 0.0176311
WASHC4 WASH complex subunit 4 0.0176205
PARD3 par-3 family cell polarity regulator 0.0176174
ARB2A ARB2 cotranscriptional regulator A 0.0175878
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.0175808
FBH1 F-box DNA helicase 1 0.0175628
SP3 Sp3 transcription factor 0.0175343
GCC2 GRIP and coiled-coil domain containing 2 0.0175264
KMT2A lysine (K)-specific methyltransferase 2A 0.0175209
KIF5B kinesin family member 5B 0.0174582
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.0174481
RPS24 ribosomal protein S24 0.0174388
TPBG trophoblast glycoprotein 0.017425
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.0174068
MRRF mitochondrial ribosome recycling factor 0.0174066
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) 0.0173821
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.0173656
CFLAR CASP8 and FADD-like apoptosis regulator 0.01733
EEA1 early endosome antigen 1 0.017283
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.0172475
KRCC1 lysine-rich coiled-coil 1 0.0172343
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 0.0172157
PPP1R13B protein phosphatase 1, regulatory subunit 13B 0.0171937
UTRN utrophin 0.0171794
SNF8 SNF8, ESCRT-II complex subunit 0.0171544
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 0.0171448
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.0171311
NFE2L2 nuclear factor, erythroid 2-like 2 0.0171244
LRP5 low density lipoprotein receptor-related protein 5 0.0171151
PHF3 PHD finger protein 3 0.0170749
SAMD1 sterile alpha motif domain containing 1 0.0170486
BRWD1 bromodomain and WD repeat domain containing 1 0.0169857
SLC25A43 solute carrier family 25, member 43 0.0169722
ERRFI1 ERBB receptor feedback inhibitor 1 0.0169703
GDE1 glycerophosphodiester phosphodiesterase 1 0.016942
EPB41L1 erythrocyte membrane protein band 4.1-like 1 0.0168878
ZMYM5 zinc finger, MYM-type 5 0.0168829
MICU2 mitochondrial calcium uptake 2 0.0168529
CRACD capping protein inhibiting regulator of actin dynamics 0.0167974
C1ORF159 chromosome 1 open reading frame 159 0.0167855
CKAP2 cytoskeleton associated protein 2 0.0167797
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.0167623
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.0167324
SMAD5 SMAD family member 5 0.0167298
MKI67 marker of proliferation Ki-67 0.0167062
MGA MGA, MAX dimerization protein 0.0166295
EDF1 endothelial differentiation-related factor 1 0.0166035
ZFYVE1 zinc finger, FYVE domain containing 1 0.016596
DTNB dystrobrevin, beta 0.0165706
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.0165648
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0165645
TLK1 tousled-like kinase 1 0.0165551
NUDCD1 NudC domain containing 1 0.0165035
SPOPL speckle-type POZ protein-like 0.0165003
DIAPH1 diaphanous-related formin 1 0.0164628
ANKRD50 ankyrin repeat domain 50 0.0164468
FUS FUS RNA binding protein 0.0163914
TENM3 teneurin transmembrane protein 3 0.0163789
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 0.0163642
ECI1 enoyl-CoA delta isomerase 1 0.0163081
SDCCAG8 serologically defined colon cancer antigen 8 0.0162999
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.0162831
EPPK1 epiplakin 1 0.0162813
TXNIP thioredoxin interacting protein 0.0162622
LTAP1 lipid transport auxiliary protein 1 0.016194
ANKRD44 ankyrin repeat domain 44 0.0161747
NT5DC3 5'-nucleotidase domain containing 3 0.0161658
PPP4R1 protein phosphatase 4, regulatory subunit 1 0.0161639
UBXN4 UBX domain protein 4 0.0160959
ZNF33A zinc finger protein 33A 0.0160947
ANAPC5 anaphase promoting complex subunit 5 0.0160728
NIPSNAP1 nipsnap homolog 1 (C. elegans) 0.0160678
LAMP2 lysosomal-associated membrane protein 2 0.016036
RCAN2 regulator of calcineurin 2 0.0160288
RPS13 ribosomal protein S13 0.0159982
SPRED2 sprouty-related, EVH1 domain containing 2 0.0159895
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.0159784
SSB Sjogren syndrome antigen B (autoantigen La) 0.0159696
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 0.0158623
BACE2 beta-site APP-cleaving enzyme 2 0.0158612
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 0.0158504
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.0158353
PDLIM7 PDZ and LIM domain 7 (enigma) 0.0158198
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 0.0158103
PHB1 prohibitin 1 0.0157507
ZNF280D zinc finger protein 280D 0.0157414
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 0.015727
EIF5 eukaryotic translation initiation factor 5 0.0157094
SHTN1 shootin 1 0.0156808
DARS1 aspartyl-tRNA synthetase 1 0.0156794
RYBP RING1 and YY1 binding protein 0.015665
GMPS guanine monphosphate synthase 0.0156643
CEP15 centrosomal protein 15 0.0156484
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.0156472
WWTR1 WW domain containing transcription regulator 1 0.0156421
RAB1B RAB1B, member RAS oncogene family 0.0156184
COBL cordon-bleu WH2 repeat protein 0.0155678
EXOSC10 exosome component 10 0.0155448
BTBD7 BTB (POZ) domain containing 7 0.015532
PSME4 proteasome (prosome, macropain) activator subunit 4 0.0154955
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.0154896
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.0154575
UBE3D ubiquitin protein ligase E3D 0.0153823
ZBTB2 zinc finger and BTB domain containing 2 0.015362
TRIM4 tripartite motif containing 4 0.0153407
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 0.0152916
XPO1 exportin 1 0.0152911
LMF1 lipase maturation factor 1 0.0151021
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans) 0.0150731
FOXN3 forkhead box N3 0.0150691
MED12 mediator complex subunit 12 0.0150252
EID1 EP300 interacting inhibitor of differentiation 1 0.0150243
ZNF124 zinc finger protein 124 0.0150115
LNX2 ligand of numb-protein X 2 0.0150104
RPL21 ribosomal protein L21 0.0149501
TM9SF3 transmembrane 9 superfamily member 3 0.0149321
RPL19 ribosomal protein L19 0.0149211
ERBB4 erb-b2 receptor tyrosine kinase 4 0.0148971
YIPF4 Yip1 domain family, member 4 0.0148954
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 0.014871
UBE2Z ubiquitin-conjugating enzyme E2Z 0.0148431
CEP170 centrosomal protein 170kDa 0.0148233
ZNF141 zinc finger protein 141 0.0147841
VEZF1 vascular endothelial zinc finger 1 0.014778
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 0.0147732
DCAF10 DDB1 and CUL4 associated factor 10 0.0147678
CERT1 ceramide transporter 1 0.0147659
TMSB10 thymosin beta 10 0.0147173
NUP62 nucleoporin 62kDa 0.0147043
AFG3L2 AFG3-like AAA ATPase 2 0.0146665
PTPRE protein tyrosine phosphatase, receptor type, E 0.0146537
ATP11C ATPase, class VI, type 11C 0.0146408
ZBTB20 zinc finger and BTB domain containing 20 0.0146142
MYH14 myosin, heavy chain 14, non-muscle 0.0146107
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.0145913
TRAM2 translocation associated membrane protein 2 0.0145572
KRI1 KRI1 homolog (S. cerevisiae) 0.0145558
LYPLAL1 lysophospholipase-like 1 0.0145346
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.014533
RAD23A RAD23 homolog A (S. cerevisiae) 0.0145325
ATP5MG ATP synthase membrane subunit g 0.0145288
FBXO9 F-box protein 9 0.0144978
CD276 CD276 molecule 0.0144881
ZFP36L1 ZFP36 ring finger protein-like 1 0.0144582
TGOLN2 trans-golgi network protein 2 0.0144468
TTC19 tetratricopeptide repeat domain 19 0.0144264
RPS16 ribosomal protein S16 0.014424
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.0144037
EEF2 eukaryotic translation elongation factor 2 0.0143878
WDR43 WD repeat domain 43 0.0143762
GSTK1 glutathione S-transferase kappa 1 0.0143679
LMCD1 LIM and cysteine-rich domains 1 0.014354
NAAA N-acylethanolamine acid amidase 0.0143521
SEPTIN11 septin 11 0.0143477
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0143468
LYPD3 LY6/PLAUR domain containing 3 0.0143412
EIF1 eukaryotic translation initiation factor 1 0.0143367
ACTN1 actinin, alpha 1 0.014322
UBE2J2 ubiquitin-conjugating enzyme E2, J2 0.0143196
TNS3 tensin 3 0.0143041
USP42 ubiquitin specific peptidase 42 0.0142858
IST1 increased sodium tolerance 1 homolog (yeast) 0.0142716
RPL36 ribosomal protein L36 0.0142685
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.0142637
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 0.0142524
SEM1 SEM1 26S proteasome subunit 0.0142443

decreased expression

Symbol Name Standardized Value
WWOX WW domain containing oxidoreductase -0.12142
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.11956
IGF1R insulin-like growth factor 1 receptor -0.113583
IFI6 interferon, alpha-inducible protein 6 -0.0802577
CALCR calcitonin receptor -0.0788821
ESR1 estrogen receptor 1 -0.0786477
GREB1 growth regulation by estrogen in breast cancer 1 -0.0772227
SPTSSB serine palmitoyltransferase, small subunit B -0.0751748
MACROD2 MACRO domain containing 2 -0.0744278
USP32 ubiquitin specific peptidase 32 -0.0663021
RAD51B RAD51 paralog B -0.0628011
CCSER1 coiled-coil serine-rich protein 1 -0.0623245
KRT18 keratin 18, type I -0.0614081
SMYD3 SET and MYND domain containing 3 -0.0599023
TUBD1 tubulin, delta 1 -0.0570182
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0531839
CUX1 cut-like homeobox 1 -0.0527335
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0527334
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0494898
GRHL2 grainyhead-like 2 (Drosophila) -0.0487543
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.0467386
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.0466189
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 -0.0448945
TRIM33 tripartite motif containing 33 -0.0439462
MED13 mediator complex subunit 13 -0.042735
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -0.0420103
GLCCI1 glucocorticoid induced 1 -0.041688
ZFHX3 zinc finger homeobox 3 -0.0416032
BCAS4 breast carcinoma amplified sequence 4 -0.0413953
CKAP5 cytoskeleton associated protein 5 -0.0411959
CCDC170 coiled-coil domain containing 170 -0.0408102
LRP1B low density lipoprotein receptor-related protein 1B -0.040492
STAT1 signal transducer and activator of transcription 1, 91kDa -0.03889
ZNF652 zinc finger protein 652 -0.0371551
GATA3 GATA binding protein 3 -0.0369149
TMEM164 transmembrane protein 164 -0.0364395
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E -0.0363501
NRCAM neuronal cell adhesion molecule -0.0362476
GOLGA4 golgin A4 -0.0361
NCOA3 nuclear receptor coactivator 3 -0.0359359
TFF1 trefoil factor 1 -0.0358545
AGO2 argonaute RISC catalytic component 2 -0.0358392
SKA2 spindle and kinetochore associated complex subunit 2 -0.0358014
GATAD2B GATA zinc finger domain containing 2B -0.0357851
FGF13 fibroblast growth factor 13 -0.0357627
AGR2 anterior gradient 2 -0.0356468
MBTD1 mbt domain containing 1 -0.0352202
TRIM37 tripartite motif containing 37 -0.0348729
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0345609
EXT1 exostosin glycosyltransferase 1 -0.0344016
GFRA1 GDNF family receptor alpha 1 -0.0343759
DCDC2 doublecortin domain containing 2 -0.0338398
FAF1 Fas (TNFRSF6) associated factor 1 -0.033808
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.0335279
KAT6B K(lysine) acetyltransferase 6B -0.0334879
SMG6 SMG6 nonsense mediated mRNA decay factor -0.0331669
CELF1 CUGBP, Elav-like family member 1 -0.0331316
ECPAS Ecm29 proteasome adaptor and scaffold -0.0329531
KMT2C lysine (K)-specific methyltransferase 2C -0.0328797
NUP160 nucleoporin 160kDa -0.0328444
AKAP13 A kinase (PRKA) anchor protein 13 -0.0327149
OLA1 Obg-like ATPase 1 -0.0325018
ACACA acetyl-CoA carboxylase alpha -0.0324785
DNMBP dynamin binding protein -0.0324492
JARID2 jumonji, AT rich interactive domain 2 -0.0323674
CFAP44 cilia and flagella associated protein 44 -0.0321356
ARHGAP32 Rho GTPase activating protein 32 -0.032089
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -0.0317473
THOC2 THO complex 2 -0.0314826
NPEPPS aminopeptidase puromycin sensitive -0.0314174
NALF1 NALCN channel auxiliary factor 1 -0.0309228
FBXL17 F-box and leucine-rich repeat protein 17 -0.0307041
GSE1 Gse1 coiled-coil protein -0.0304373
RAB11FIP3 RAB11 family interacting protein 3 (class II) -0.0303529
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) -0.0300949
NUP153 nucleoporin 153kDa -0.0300237
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.0300125
TRAPPC9 trafficking protein particle complex 9 -0.0297642
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.0293636
RBM15 RNA binding motif protein 15 -0.0293398
LURAP1L leucine rich adaptor protein 1-like -0.0293372
PDZRN3 PDZ domain containing ring finger 3 -0.0291138
XBP1 X-box binding protein 1 -0.0285631
SFPQ splicing factor proline/glutamine-rich -0.0284895
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase -0.0283748
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0281832
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0280843
NRG3 neuregulin 3 -0.0279928
GATAD2A GATA zinc finger domain containing 2A -0.0278266
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -0.027741
NMD3 NMD3 ribosome export adaptor -0.0273205
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 -0.0271873
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -0.0270182
DENND1A DENN/MADD domain containing 1A -0.0269971
MON2 MON2 homolog (S. cerevisiae) -0.0269247
CA12 carbonic anhydrase XII -0.02687
ELOVL1 ELOVL fatty acid elongase 1 -0.0268542
PUM1 pumilio RNA-binding family member 1 -0.0267842
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -0.0267785
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) -0.0266756
MYO1B myosin IB -0.0266263
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0266067
GNA12 guanine nucleotide binding protein (G protein) alpha 12 -0.0265655
MACROD1 MACRO domain containing 1 -0.0265287
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 -0.0262533
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0262412
SYTL2 synaptotagmin-like 2 -0.0261956
TOP6BL TOP6B like initiator of meiotic double strand breaks -0.0261801
EDC3 enhancer of mRNA decapping 3 -0.0261716
SQLE squalene epoxidase -0.0260668
TOP1 topoisomerase (DNA) I -0.0259128
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 -0.025853
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0254895
RABGAP1L RAB GTPase activating protein 1-like -0.0254178
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa -0.0253234
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.0253118
ADIPOR2 adiponectin receptor 2 -0.0252754
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 -0.0252189
TPD52L1 tumor protein D52-like 1 -0.0251869
LTBP1 latent transforming growth factor beta binding protein 1 -0.0250611
DYNC2I2 dynein 2 intermediate chain 2 -0.0250298
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0249842
RBM47 RNA binding motif protein 47 -0.024822
MIPEP mitochondrial intermediate peptidase -0.024412
NRDC nardilysin convertase -0.0243551
PPP6R3 protein phosphatase 6, regulatory subunit 3 -0.0243047
MROH1 maestro heat-like repeat family member 1 -0.0242996
SARS2 seryl-tRNA synthetase 2, mitochondrial -0.024256
KPNB1 karyopherin (importin) beta 1 -0.0242524
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta -0.0241107
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 -0.024006
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -0.0239331
ZHX3 zinc fingers and homeoboxes 3 -0.0238373
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.0236956
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.0236075
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 -0.023595
UBA1 ubiquitin-like modifier activating enzyme 1 -0.0235865
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) -0.0235529
EIF3A eukaryotic translation initiation factor 3, subunit A -0.023546
STRBP spermatid perinuclear RNA binding protein -0.0233885
TSC22D1 TSC22 domain family, member 1 -0.0232699
RMDN1 regulator of microtubule dynamics 1 -0.0231383
NCOR1 nuclear receptor corepressor 1 -0.0231141
MED13L mediator complex subunit 13-like -0.0229542
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.0229344
TNPO2 transportin 2 -0.0227963
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.02266
SSBP2 single-stranded DNA binding protein 2 -0.0226217
NFIB nuclear factor I/B -0.0226044
ZFYVE9 zinc finger, FYVE domain containing 9 -0.022603
MED12L mediator complex subunit 12-like -0.0225373
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -0.0225216
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) -0.0224467
RNGTT RNA guanylyltransferase and 5'-phosphatase -0.0223697
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.0223471
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -0.0223092
MEF2A myocyte enhancer factor 2A -0.0222622
RAD21 RAD21 homolog (S. pombe) -0.0221311
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) -0.0220527
FTO fat mass and obesity associated -0.0220246
MBD5 methyl-CpG binding domain protein 5 -0.0219651
RTN4RL1 reticulon 4 receptor-like 1 -0.0219516
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.0219347
CPA6 carboxypeptidase A6 -0.0219273
COP1 COP1 E3 ubiquitin ligase -0.0218914
CMSS1 cms1 ribosomal small subunit homolog (yeast) -0.0218743
SENP5 SUMO1/sentrin specific peptidase 5 -0.0218334
TUBB4B tubulin, beta 4B class IVb -0.0217605
R3HDM2 R3H domain containing 2 -0.0215369
SIDT1 SID1 transmembrane family, member 1 -0.0215134
MALRD1 MAM and LDL receptor class A domain containing 1 -0.0215094
DDB2 damage-specific DNA binding protein 2, 48kDa -0.0215075
SRPK2 SRSF protein kinase 2 -0.0215055
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -0.0214931
CUL3 cullin 3 -0.0214437
ATP5MJ ATP synthase membrane subunit j -0.0212645
GPHN gephyrin -0.0212603
HAT1 histone acetyltransferase 1 -0.0212313
AK1 adenylate kinase 1 -0.0212288
ZFYVE16 zinc finger, FYVE domain containing 16 -0.0212215
KAT6A K(lysine) acetyltransferase 6A -0.0211878
PPP6C protein phosphatase 6, catalytic subunit -0.0211532
DSCAM Down syndrome cell adhesion molecule -0.0210395
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -0.0208702
CLASP1 cytoplasmic linker associated protein 1 -0.0208587
GPATCH2 G patch domain containing 2 -0.020835
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0208341
NUP214 nucleoporin 214kDa -0.0206878
TFF3 trefoil factor 3 (intestinal) -0.0206661
CADPS2 Ca++-dependent secretion activator 2 -0.0206056
AHI1 Abelson helper integration site 1 -0.0206005
SPATS2 spermatogenesis associated, serine-rich 2 -0.0205562
TOP2B topoisomerase (DNA) II beta 180kDa -0.0205374
MAST4 microtubule associated serine/threonine kinase family member 4 -0.0205093
ZDHHC14 zinc finger, DHHC-type containing 14 -0.0204779
COQ10B coenzyme Q10 homolog B (S. cerevisiae) -0.0204582
OSBPL2 oxysterol binding protein-like 2 -0.0204541
PRRC2B proline-rich coiled-coil 2B -0.0203371
PRKCE protein kinase C, epsilon -0.0203305
CEMIP2 cell migration inducing hyaluronidase 2 -0.0203105
CDK5RAP2 CDK5 regulatory subunit associated protein 2 -0.0202384
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.0202283
C1ORF21 chromosome 1 open reading frame 21 -0.020228
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.0201669
ZC3H18 zinc finger CCCH-type containing 18 -0.0201643
UBAC2 UBA domain containing 2 -0.0201634
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 -0.0200678
BIRC6 baculoviral IAP repeat containing 6 -0.0199855
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 -0.0199698
PCED1B PC-esterase domain containing 1B -0.0199121
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -0.0198619
TMEM165 transmembrane protein 165 -0.0198304
POTEF POTE ankyrin domain family, member F -0.0197728
MAP3K3 mitogen-activated protein kinase kinase kinase 3 -0.0197417
SRRM2 serine/arginine repetitive matrix 2 -0.0197012
WNK1 WNK lysine deficient protein kinase 1 -0.0196634
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.0196429
MTA3 metastasis associated 1 family, member 3 -0.0196359
ZBTB35 zinc finger and BTB domain containing 35 -0.0195735
RPS18 ribosomal protein S18 -0.0195589
TBCK TBC1 domain containing kinase -0.0195053
PBX3 pre-B-cell leukemia homeobox 3 -0.0194917
SCCPDH saccharopine dehydrogenase (putative) -0.0194184
ATE1 arginyltransferase 1 -0.0193557
RFX7 regulatory factor X, 7 -0.0193188
TOM1L2 target of myb1-like 2 (chicken) -0.0192421
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.0191722
IVD isovaleryl-CoA dehydrogenase -0.0191696
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase -0.0191526
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -0.0190681
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0189855
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -0.0189159
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 -0.0187563
NKTR natural killer cell triggering receptor -0.0187537
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein -0.0187409
HM13 histocompatibility (minor) 13 -0.0187309
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.0187228
ANAPC16 anaphase promoting complex subunit 16 -0.01869
ADNP activity-dependent neuroprotector homeobox -0.0186555
PIBF1 progesterone immunomodulatory binding factor 1 -0.0186336
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 -0.0184857
DPY30 dpy-30 homolog (C. elegans) -0.0184756
ITPRID2 ITPR interacting domain containing 2 -0.0184592
ASCC3 activating signal cointegrator 1 complex subunit 3 -0.0184333
ZC3H13 zinc finger CCCH-type containing 13 -0.0183812
MICU1 mitochondrial calcium uptake 1 -0.0182544
DOCK1 dedicator of cytokinesis 1 -0.0182417
NUMB numb homolog (Drosophila) -0.0181317
BMP2K BMP2 inducible kinase -0.0181146
CHD9 chromodomain helicase DNA binding protein 9 -0.0180389
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0180262
TPD52L2 tumor protein D52-like 2 -0.017921
FKBP4 FK506 binding protein 4, 59kDa -0.0178251
BMPR1A bone morphogenetic protein receptor, type IA -0.0177274
MUC16 mucin 16, cell surface associated -0.0176825
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -0.0176702
PTBP2 polypyrimidine tract binding protein 2 -0.0176659
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.0176656
AHCTF1 AT hook containing transcription factor 1 -0.0175561
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 -0.0174864
BAG3 BCL2-associated athanogene 3 -0.0174846
SMC4 structural maintenance of chromosomes 4 -0.0174658
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -0.0174653
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -0.0174584
STAU1 staufen double-stranded RNA binding protein 1 -0.0174583
KPNA1 karyopherin alpha 1 (importin alpha 5) -0.0174155
FANCA Fanconi anemia, complementation group A -0.0173372
CDC50A cell division cycle 50 P4-ATPase accessory subunit A -0.0173355
NAP1L4 nucleosome assembly protein 1-like 4 -0.0173313
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0173125
TRA2B transformer 2 beta homolog (Drosophila) -0.0173105
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -0.0173008
RUSC2 RUN and SH3 domain containing 2 -0.0172773
RANGAP1 Ran GTPase activating protein 1 -0.0172676
NUP98 nucleoporin 98kDa -0.0172641
KANSL3 KAT8 regulatory NSL complex subunit 3 -0.0172495
MAP7 microtubule-associated protein 7 -0.0172443
FRMD5 FERM domain containing 5 -0.0171505
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 -0.0171283
TOM1L1 target of myb1 (chicken)-like 1 -0.017128
BRCA2 breast cancer 2, early onset -0.0170319
DAAM1 dishevelled associated activator of morphogenesis 1 -0.0169791
EIPR1 EARP complex and GARP complex interacting protein 1 -0.016966
TP53 tumor protein p53 -0.0169406
IDE insulin-degrading enzyme -0.0169285
ZC3H7B zinc finger CCCH-type containing 7B -0.0168529
RSRC1 arginine/serine-rich coiled-coil 1 -0.0168157
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.0168068
CDYL2 chromodomain protein, Y-like 2 -0.0167915
WDR20 WD repeat domain 20 -0.0167511
RPS25 ribosomal protein S25 -0.0167222
PLCB4 phospholipase C, beta 4 -0.016715
FYCO1 FYVE and coiled-coil domain containing 1 -0.0166975
PTPRG protein tyrosine phosphatase, receptor type, G -0.0166739
CA8 carbonic anhydrase VIII -0.0166688
ZNF638 zinc finger protein 638 -0.0166586
CSNK1G1 casein kinase 1, gamma 1 -0.0166579
DPY19L4 dpy-19-like 4 (C. elegans) -0.0166322
SNX27 sorting nexin family member 27 -0.0166232
FMN1 formin 1 -0.0166191
ZNF318 zinc finger protein 318 -0.016615
CHD8 chromodomain helicase DNA binding protein 8 -0.0166104
TTC28 tetratricopeptide repeat domain 28 -0.0165972
TMEM120B transmembrane protein 120B -0.0165968
ASF1B anti-silencing function 1B histone chaperone -0.0165687
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase -0.0165617
NCOR2 nuclear receptor corepressor 2 -0.0165395
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0165254
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) -0.0164992
CENATAC centrosomal AT-AC splicing factor -0.0164681
UVRAG UV radiation resistance associated -0.0164542
VTA1 vesicle (multivesicular body) trafficking 1 -0.0164159
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -0.0164111
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -0.0164073
E2F6 E2F transcription factor 6 -0.0163993
LYN LYN proto-oncogene, Src family tyrosine kinase -0.0163947
PA2G4 proliferation-associated 2G4, 38kDa -0.0163515
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) -0.0163113
ITM2C integral membrane protein 2C -0.0161523
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 -0.0161371
LIN9 lin-9 DREAM MuvB core complex component -0.0160854
DGKE diacylglycerol kinase, epsilon 64kDa -0.0160535
TRIM14 tripartite motif containing 14 -0.0160299
RTN3 reticulon 3 -0.0160063
CLEC16A C-type lectin domain family 16, member A -0.015973
GSTM3 glutathione S-transferase mu 3 (brain) -0.0159549
TPR translocated promoter region, nuclear basket protein -0.0159543
BCL7A B-cell CLL/lymphoma 7A -0.015913
EHMT1 euchromatic histone-lysine N-methyltransferase 1 -0.0159053
RBL2 retinoblastoma-like 2 -0.0158201
CKAP4 cytoskeleton-associated protein 4 -0.0157843
TTLL10 tubulin tyrosine ligase-like family member 10 -0.015737
H3C4 H3 clustered histone 4 -0.0157085
MINK1 misshapen-like kinase 1 -0.0156924
GREB1L growth regulation by estrogen in breast cancer-like -0.0156674
KDM6A lysine (K)-specific demethylase 6A -0.0156672
GPATCH2L G patch domain containing 2-like -0.0156663
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 -0.0156238
PARP6 poly (ADP-ribose) polymerase family, member 6 -0.0155938
EPCAM epithelial cell adhesion molecule -0.0155657
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 -0.0155628
MAML3 mastermind-like 3 (Drosophila) -0.0155289
SLTM SAFB-like, transcription modulator -0.0155243
VWA8 von Willebrand factor A domain containing 8 -0.0154337
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -0.0154321
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.015401
IGFBP4 insulin-like growth factor binding protein 4 -0.0153865
ZBTB4 zinc finger and BTB domain containing 4 -0.015328
ABR active BCR-related -0.0153009
KCTD20 potassium channel tetramerization domain containing 20 -0.0152477
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) -0.0152339
GANAB glucosidase, alpha; neutral AB -0.0152204
GMDS GDP-mannose 4,6-dehydratase -0.015206
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0151502
PTPN2 protein tyrosine phosphatase, non-receptor type 2 -0.0151397
LRP11 low density lipoprotein receptor-related protein 11 -0.01512
UBE2O ubiquitin-conjugating enzyme E2O -0.0151195
NR6A1 nuclear receptor subfamily 6, group A, member 1 -0.0151063
HIPK1 homeodomain interacting protein kinase 1 -0.0150877
SOS1 son of sevenless homolog 1 (Drosophila) -0.0150648
ATP5MC1 ATP synthase membrane subunit c locus 1 -0.0150473
CD58 CD58 molecule -0.0150235
AKAP9 A kinase (PRKA) anchor protein 9 -0.0150183
SCARB1 scavenger receptor class B, member 1 -0.0149844
NEK1 NIMA-related kinase 1 -0.0149842
KIF20B kinesin family member 20B -0.0149782
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0149687
SUMF2 sulfatase modifying factor 2 -0.0149681
PRKCI protein kinase C, iota -0.0149656
ZMYM2 zinc finger, MYM-type 2 -0.0149368
ZMYND11 zinc finger, MYND-type containing 11 -0.0149327
HSPA1A heat shock 70kDa protein 1A -0.0149023
MAN1A2 mannosidase, alpha, class 1A, member 2 -0.0147989
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -0.0147881
PCDHB16 protocadherin beta 16 -0.0147656
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) -0.0147491
CDK13 cyclin-dependent kinase 13 -0.0147302
MAP2K1 mitogen-activated protein kinase kinase 1 -0.0146671
BPTF bromodomain PHD finger transcription factor -0.0146645
EVI5 ecotropic viral integration site 5 -0.014658
PTK2 protein tyrosine kinase 2 -0.0146313
TRIP12 thyroid hormone receptor interactor 12 -0.0146211
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 -0.0146097
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) -0.0145954
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0145804
KDM3B lysine (K)-specific demethylase 3B -0.0145635
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0145618
DHRS7B dehydrogenase/reductase (SDR family) member 7B -0.0145525
FHIP1A FHF complex subunit HOOK interacting protein 1A -0.0145427
SLF2 SMC5-SMC6 complex localization factor 2 -0.0145417
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 -0.0145384
FANCC Fanconi anemia, complementation group C -0.0145304
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -0.0145281
SHANK2 SH3 and multiple ankyrin repeat domains 2 -0.0145111
ECT2 epithelial cell transforming 2 -0.0145044
SULF2 sulfatase 2 -0.0144872
AGFG1 ArfGAP with FG repeats 1 -0.014472
RNFT2 ring finger protein, transmembrane 2 -0.0144549
PEDS1 plasmanylethanolamine desaturase 1 -0.0144338
SBNO2 strawberry notch homolog 2 (Drosophila) -0.0144249
MGLL monoglyceride lipase -0.0144202
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.0144098
KANSL1 KAT8 regulatory NSL complex subunit 1 -0.0143963
SYNPO2 synaptopodin 2 -0.0143961
DNASE1 deoxyribonuclease I -0.0143742
PUM3 pumilio RNA binding family member 3 -0.0143697
LCORL ligand dependent nuclear receptor corepressor-like -0.0143208
LDLRAD3 low density lipoprotein receptor class A domain containing 3 -0.01431
PCNT pericentrin -0.0142548
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) -0.0142267
TMTC3 transmembrane and tetratricopeptide repeat containing 3 -0.0142263
PRPF38B pre-mRNA processing factor 38B -0.0142155
MSI2 musashi RNA-binding protein 2 -0.014203
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1 -0.0141932
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -0.0141776
RAB7A RAB7A, member RAS oncogene family -0.0141735
APTX aprataxin -0.0141635
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -0.0141532
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 -0.0141282
KIF18B kinesin family member 18B -0.0141262
RASGEF1B RasGEF domain family, member 1B -0.0141231
DOCK6 dedicator of cytokinesis 6 -0.0141091
TMEM9 transmembrane protein 9 -0.0140893
CDR2 cerebellar degeneration-related protein 2, 62kDa -0.0140412
FAM120B family with sequence similarity 120B -0.0140382
RHOBTB3 Rho-related BTB domain containing 3 -0.0140206
MRPS27 mitochondrial ribosomal protein S27 -0.0140174
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 -0.0139938
CITED4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 -0.0139894
NVL nuclear VCP-like -0.0139886
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial -0.0139598
EEIG1 estrogen-induced osteoclastogenesis regulator 1 -0.0139472
SFMBT1 Scm-like with four mbt domains 1 -0.0139333
FAM120C family with sequence similarity 120C -0.0138912
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -0.0138679
XPA xeroderma pigmentosum, complementation group A -0.0138557
AP1B1 adaptor-related protein complex 1, beta 1 subunit -0.0138407
ACSL3 acyl-CoA synthetase long-chain family member 3 -0.0138249
BLTP3A bridge-like lipid transfer protein family member 3A -0.013816
LGALS12 lectin, galactoside-binding, soluble, 12 -0.0137172
KMT2E lysine (K)-specific methyltransferase 2E -0.0137106
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -0.013706
PRDX1 peroxiredoxin 1 -0.0136987
GLG1 golgi glycoprotein 1 -0.0136687
MYO10 myosin X -0.0136577
GMEB1 glucocorticoid modulatory element binding protein 1 -0.013615
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.0135993
FNBP1L formin binding protein 1-like -0.0135912
CCDC47 coiled-coil domain containing 47 -0.0135737
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0135524
ZNF107 zinc finger protein 107 -0.0135124
MYO16 myosin XVI -0.0134938
ECHDC2 enoyl CoA hydratase domain containing 2 -0.0134933
TAC4 tachykinin 4 (hemokinin) -0.0134662
NHSL1 NHS-like 1 -0.0134489
FBXW8 F-box and WD repeat domain containing 8 -0.0134446
CHD3 chromodomain helicase DNA binding protein 3 -0.013412
USP37 ubiquitin specific peptidase 37 -0.0133604
PAIP2 poly(A) binding protein interacting protein 2 -0.01335
GDI2 GDP dissociation inhibitor 2 -0.0133433
EIF3G eukaryotic translation initiation factor 3, subunit G -0.0133292
EXOC7 exocyst complex component 7 -0.0133146
SDK1 sidekick cell adhesion molecule 1 -0.0132997
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) -0.0132978
PDS5B PDS5 cohesin associated factor B -0.0132902
CRYBG1 crystallin beta-gamma domain containing 1 -0.0132839
NCOA6 nuclear receptor coactivator 6 -0.0132678
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 -0.0132655
BCAS1 breast carcinoma amplified sequence 1 -0.0132584
MANBA mannosidase, beta A, lysosomal -0.01325
EGFL7 EGF-like-domain, multiple 7 -0.0132296
SCAF4 SR-related CTD-associated factor 4 -0.0132164
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -0.0132015
KDM4B lysine (K)-specific demethylase 4B -0.0131884
AGK acylglycerol kinase -0.0131554
MELK maternal embryonic leucine zipper kinase -0.0131442
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) -0.0131433
ARL15 ADP-ribosylation factor-like 15 -0.0131337
ADGRV1 adhesion G protein-coupled receptor V1 -0.0131095
TSC22D4 TSC22 domain family, member 4 -0.0130969
MSMB microseminoprotein, beta- -0.0130761
MPRIP myosin phosphatase Rho interacting protein -0.0130745
PTBP3 polypyrimidine tract binding protein 3 -0.0130643
DBF4B DBF4 zinc finger B -0.0130421
VAV3 vav 3 guanine nucleotide exchange factor -0.0130295
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.013
ADAM22 ADAM metallopeptidase domain 22 -0.0129858
FER fer (fps/fes related) tyrosine kinase -0.0129689
ANKIB1 ankyrin repeat and IBR domain containing 1 -0.0129624
DCAF13 DDB1 and CUL4 associated factor 13 -0.0129613
KTN1 kinectin 1 (kinesin receptor) -0.0129384
WDR33 WD repeat domain 33 -0.0129265
NPNT nephronectin -0.0129228
ATG7 autophagy related 7 -0.0129227
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 -0.0129083
MRFAP1 Morf4 family associated protein 1 -0.0128883
RAB5A RAB5A, member RAS oncogene family -0.0128121
WBP1L WW domain binding protein 1-like -0.0128014
KIAA0513 KIAA0513 -0.012797
RC3H2 ring finger and CCCH-type domains 2 -0.012794