MCF7_Obatoclax Mesylate_10µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description Obatoclax Mesylate 10µM perturbation in MCF7 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the MCF7_Obatoclax Mesylate_10µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.288257
HSPB1 heat shock 27kDa protein 1 0.139012
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.133433
NCOA3 nuclear receptor coactivator 3 0.117159
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.113653
FTH1 ferritin, heavy polypeptide 1 0.110279
SQSTM1 sequestosome 1 0.0936457
ACTG1 actin gamma 1 0.0842331
UBL4A ubiquitin-like 4A 0.0809101
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.0795082
USP32 ubiquitin specific peptidase 32 0.0777825
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.0745441
SOX4 SRY (sex determining region Y)-box 4 0.067497
TXNRD1 thioredoxin reductase 1 0.065101
PTPRK protein tyrosine phosphatase, receptor type, K 0.0636531
FDPS farnesyl diphosphate synthase 0.063196
DTNA dystrobrevin, alpha 0.0618869
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.0602792
SQLE squalene epoxidase 0.0591449
DSPP dentin sialophosphoprotein 0.0589548
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.0574735
BRWD1 bromodomain and WD repeat domain containing 1 0.055623
DAAM1 dishevelled associated activator of morphogenesis 1 0.0551536
MRPL13 mitochondrial ribosomal protein L13 0.0534883
KRT80 keratin 80, type II 0.0525522
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.052505
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.0518214
PACS1 phosphofurin acidic cluster sorting protein 1 0.0516606
SPAG9 sperm associated antigen 9 0.0515151
KDM5B lysine (K)-specific demethylase 5B 0.0506927
STAT1 signal transducer and activator of transcription 1, 91kDa 0.048515
ERRFI1 ERBB receptor feedback inhibitor 1 0.0477155
NAV1 neuron navigator 1 0.0475246
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0475181
PCDHB16 protocadherin beta 16 0.0466484
LDLR low density lipoprotein receptor 0.04658
RACK1 receptor for activated C kinase 1 0.046127
GDF15 growth differentiation factor 15 0.0459435
PMEPA1 prostate transmembrane protein, androgen induced 1 0.0446531
CDPF1 cysteine-rich, DPF motif domain containing 1 0.0430574
SPIRE1 spire-type actin nucleation factor 1 0.0430211
TRIM56 tripartite motif containing 56 0.0428422
GTF2IRD1 GTF2I repeat domain containing 1 0.0426077
NEBL nebulette 0.0421498
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.041607
RPS2 ribosomal protein S2 0.040095
NRP1 neuropilin 1 0.0393593
FLNA filamin A, alpha 0.0389586
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.0389105
AREG amphiregulin 0.038596
RPS9 ribosomal protein S9 0.0379469
MUSK muscle, skeletal, receptor tyrosine kinase 0.0377707
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0374246
PARP14 poly (ADP-ribose) polymerase family, member 14 0.0363843
SMAD3 SMAD family member 3 0.0355107
H3-3B H3.3 histone B 0.0352639
TFF1 trefoil factor 1 0.0347947
GOLGB1 golgin B1 0.0346975
RPL13A ribosomal protein L13a 0.0346185
CLIP1 CAP-GLY domain containing linker protein 1 0.0342014
UBC ubiquitin C 0.0339062
TMSB10 thymosin beta 10 0.0338589
ANKRD11 ankyrin repeat domain 11 0.0336654
RPLP1 ribosomal protein, large, P1 0.0335686
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.03334
TKT transketolase 0.0329161
AKR1C2 aldo-keto reductase family 1, member C2 0.0328346
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0327769
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.032357
ZFHX3 zinc finger homeobox 3 0.0319573
KMT2C lysine (K)-specific methyltransferase 2C 0.03179
FNDC3B fibronectin type III domain containing 3B 0.0317609
TRIO trio Rho guanine nucleotide exchange factor 0.0317205
ULK1 unc-51 like autophagy activating kinase 1 0.0317162
MLPH melanophilin 0.0316139
RPS15 ribosomal protein S15 0.0314305
EEF2 eukaryotic translation elongation factor 2 0.0313156
ISG15 ISG15 ubiquitin-like modifier 0.0311214
FTL ferritin, light polypeptide 0.0310706
MLXIP MLX interacting protein 0.0303892
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0297825
RPL28 ribosomal protein L28 0.0297812
CAPN8 calpain 8 0.0295368
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.0294139
CTSD cathepsin D 0.0292819
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) 0.0290635
SFTPA2 surfactant protein A2 0.0289014
LPP LIM domain containing preferred translocation partner in lipoma 0.0288127
SKIL SKI-like proto-oncogene 0.0285357
RRBP1 ribosome binding protein 1 0.028431
S100A11 S100 calcium binding protein A11 0.0283721
LGALS3 lectin, galactoside-binding, soluble, 3 0.0282372
WARS1 tryptophanyl-tRNA synthetase 1 0.0282102
PCED1B PC-esterase domain containing 1B 0.0280328
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.027901
MED13 mediator complex subunit 13 0.0275401
RPS19 ribosomal protein S19 0.0271921
LURAP1L leucine rich adaptor protein 1-like 0.02713
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0271178
ACSS2 acyl-CoA synthetase short-chain family member 2 0.0265614
GSE1 Gse1 coiled-coil protein 0.026227
KYNU kynureninase 0.0261069
MAPK6 mitogen-activated protein kinase 6 0.0258955
GSK3B glycogen synthase kinase 3 beta 0.0257404
HELZ2 helicase with zinc finger 2, transcriptional coactivator 0.0257223
KDM2A lysine (K)-specific demethylase 2A 0.0256016
DMGDH dimethylglycine dehydrogenase 0.0255491
IER3 immediate early response 3 0.0255322
MAP1B microtubule-associated protein 1B 0.025452
RPS11 ribosomal protein S11 0.0253
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 0.0252831
RPL37 ribosomal protein L37 0.0251822
SREBF2 sterol regulatory element binding transcription factor 2 0.0241768
RPS17 ribosomal protein S17 0.0239038
RPL29 ribosomal protein L29 0.0236941
IDI1 isopentenyl-diphosphate delta isomerase 1 0.0236552
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0236464
MAP4 microtubule-associated protein 4 0.0234829
EIF1 eukaryotic translation initiation factor 1 0.0233824
RBM47 RNA binding motif protein 47 0.0232237
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.0231058
SUCO SUN domain containing ossification factor 0.0231056
RPS16 ribosomal protein S16 0.023105
LHFPL2 lipoma HMGIC fusion partner-like 2 0.0229
FOXN3 forkhead box N3 0.0227468
MYH14 myosin, heavy chain 14, non-muscle 0.0227079
NFE2L1 nuclear factor, erythroid 2-like 1 0.0226024
DST dystonin 0.0224419
RNF223 ring finger protein 223 0.0221233
TTC3 tetratricopeptide repeat domain 3 0.0218666
IER5L immediate early response 5-like 0.0218364
TLK2 tousled-like kinase 2 0.0218255
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.021807
AARS1 alanyl-tRNA synthetase 1 0.0217812
PALLD palladin, cytoskeletal associated protein 0.0215305
LARP1 La ribonucleoprotein domain family, member 1 0.0215185
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.0214514
PTPRJ protein tyrosine phosphatase, receptor type, J 0.0213866
ARL15 ADP-ribosylation factor-like 15 0.0212427
NFE2L2 nuclear factor, erythroid 2-like 2 0.0211908
LOC112694756 uncharaterized LOC112694756 0.0210453
S100A14 S100 calcium binding protein A14 0.0210239
SLC38A2 solute carrier family 38, member 2 0.020989
ATP9A ATPase, class II, type 9A 0.0209563
RIGI RNA sensor RIG-I 0.0209527
MAP3K20 mitogen-activated protein kinase kinase kinase 20 0.0209135
SEC31A SEC31 homolog A (S. cerevisiae) 0.0208139
ZNFX1 zinc finger, NFX1-type containing 1 0.0205338
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 0.020511
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 0.0204263
AMZ1 archaelysin family metallopeptidase 1 0.0204114
SESN2 sestrin 2 0.0202641
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0202176
ZDHHC7 zinc finger, DHHC-type containing 7 0.0201831
ADAR adenosine deaminase, RNA-specific 0.0201712
N4BP2L2 NEDD4 binding protein 2-like 2 0.0201149
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.0200827
AFF4 AF4/FMR2 family, member 4 0.0200656
KLHL24 kelch-like family member 24 0.0200488
ZFAND3 zinc finger, AN1-type domain 3 0.0199328
GATAD2B GATA zinc finger domain containing 2B 0.0199319
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0199259
MRTFA myocardin related transcription factor A 0.0198619
TRAF3 TNF receptor-associated factor 3 0.0198372
FOXO3 forkhead box O3 0.0197922
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 0.019753
RPL12 ribosomal protein L12 0.019732
SPPL3 signal peptide peptidase like 3 0.0197221
RPS5 ribosomal protein S5 0.0197201
ENOSF1 enolase superfamily member 1 0.019648
GOLGA2 golgin A2 0.0196308
YY1 YY1 transcription factor 0.0194724
ACTN1 actinin, alpha 1 0.0194151
ARFGEF3 ARFGEF family member 3 0.0194046
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.0192914
RB1CC1 RB1-inducible coiled-coil 1 0.0192725
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) 0.0192698
SETD2 SET domain containing 2 0.0192145
IFITM3 interferon induced transmembrane protein 3 0.0191831
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0190946
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 0.0190204
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 0.0190136
LPIN1 lipin 1 0.0188814
TRIB3 tribbles pseudokinase 3 0.0188541
ECE1 endothelin converting enzyme 1 0.0187244
UBE2H ubiquitin-conjugating enzyme E2H 0.0186459
PLEC plectin 0.0185478
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.0183355
ANXA2 annexin A2 0.0182486
GCLC glutamate-cysteine ligase, catalytic subunit 0.0181017
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.0179926
SP100 SP100 nuclear antigen 0.0178444
ARID3A AT rich interactive domain 3A (BRIGHT-like) 0.0177827
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0177476
BCL9L B-cell CLL/lymphoma 9-like 0.0177115
RPLP0 ribosomal protein, large, P0 0.017678
KLF6 Kruppel-like factor 6 0.0176494
NQO1 NAD(P)H dehydrogenase, quinone 1 0.0176367
ARID4B AT rich interactive domain 4B (RBP1-like) 0.0176056
ITGAV integrin, alpha V 0.0176018
RPS18 ribosomal protein S18 0.017542
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.0175263
XPOT exportin, tRNA 0.0175014
HOMER2 homer scaffolding protein 2 0.0174332
RPL18 ribosomal protein L18 0.0173854
MYO1B myosin IB 0.0173583
AAK1 AP2 associated kinase 1 0.0172954
UST uronyl-2-sulfotransferase 0.0172725
MVD mevalonate (diphospho) decarboxylase 0.0172015
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) 0.0169721
GIPC1 GIPC PDZ domain containing family, member 1 0.0169573
TOP1 topoisomerase (DNA) I 0.0169436
TRIM37 tripartite motif containing 37 0.0169423
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 0.0169076
S100A10 S100 calcium binding protein A10 0.0168577
RNF213 ring finger protein 213 0.0168567
CHKA choline kinase alpha 0.0167778
PAWR PRKC, apoptosis, WT1, regulator 0.0167541
MORF4L2 mortality factor 4 like 2 0.016684
BUB3 BUB3 mitotic checkpoint protein 0.0165993
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.0165721
VGLL4 vestigial-like family member 4 0.0164305
HM13 histocompatibility (minor) 13 0.0163642
SAMD4A sterile alpha motif domain containing 4A 0.0162407
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.0161845
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.0161043
TESK2 testis-specific kinase 2 0.0160512
TPCN1 two pore segment channel 1 0.0160225
ABLIM1 actin binding LIM protein 1 0.0159771
SLA2 Src-like-adaptor 2 0.0158846
IFI27 interferon, alpha-inducible protein 27 0.0158666
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.015806
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 0.0157795
CEP95 centrosomal protein 95kDa 0.0157425
EMCN endomucin 0.0157322
CKAP4 cytoskeleton-associated protein 4 0.0157216
CLCN7 chloride channel, voltage-sensitive 7 0.0156919
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.015673
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.0156641
UBXN1 UBX domain protein 1 0.0155591
CSDE1 cold shock domain containing E1, RNA-binding 0.0155033
PTGR1 prostaglandin reductase 1 0.0154711
CD63 CD63 molecule 0.0153382
NPC1 Niemann-Pick disease, type C1 0.0153069
DDIT4 DNA-damage-inducible transcript 4 0.0152995
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.01527
KRT81 keratin 81, type II 0.0152175
RPL35 ribosomal protein L35 0.0151374
NLN neurolysin (metallopeptidase M3 family) 0.0151067
ZYX zyxin 0.0150855
INSIG1 insulin induced gene 1 0.0150432
BHLHE40 basic helix-loop-helix family, member e40 0.0150416
YARS1 tyrosyl-tRNA synthetase 1 0.0150023
MROH1 maestro heat-like repeat family member 1 0.0149699
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0149683
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 0.0149215
BMERB1 bMERB domain containing 1 0.014832
SVIL supervillin 0.0147859
CAMK2D calcium/calmodulin-dependent protein kinase II delta 0.0147643
RPL10A ribosomal protein L10a 0.014759
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.0147437
RPS14 ribosomal protein S14 0.0147286
LITAF lipopolysaccharide-induced TNF factor 0.0146555
TACC2 transforming, acidic coiled-coil containing protein 2 0.0146083
HYOU1 hypoxia up-regulated 1 0.0145713
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.0145119
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2 0.0144656
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.0144618
NCKAP1 NCK-associated protein 1 0.0144453
MAP7 microtubule-associated protein 7 0.0144296
RAB40C RAB40C, member RAS oncogene family 0.0144261
SEC24A SEC24 family member A 0.014426
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0143692
MYO9A myosin IXA 0.0143116
PCNX1 pecanex 1 0.0142758
KDM6B lysine (K)-specific demethylase 6B 0.0142665
RPS4X ribosomal protein S4, X-linked 0.0142211
NRCAM neuronal cell adhesion molecule 0.014214
RAB1A RAB1A, member RAS oncogene family 0.0142102
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.0141994
SUSD6 sushi domain containing 6 0.0141727
SH3KBP1 SH3-domain kinase binding protein 1 0.0141472
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 0.0141232
ARHGAP21 Rho GTPase activating protein 21 0.0140772
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.0139993
VCP valosin containing protein 0.0139954
SCCPDH saccharopine dehydrogenase (putative) 0.0139747
JMJD1C jumonji domain containing 1C 0.0139464
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.0139175
EIF3G eukaryotic translation initiation factor 3, subunit G 0.0138704
IARS1 isoleucyl-tRNA synthetase 1 0.0138627
CCDC6 coiled-coil domain containing 6 0.0138113
CD44 CD44 molecule (Indian blood group) 0.0137811
CHD9 chromodomain helicase DNA binding protein 9 0.0137393
RPS3 ribosomal protein S3 0.0137119
IRF2BP2 interferon regulatory factor 2 binding protein 2 0.0137116
ZFP36L1 ZFP36 ring finger protein-like 1 0.0136913
FOXO1 forkhead box O1 0.0136902
PHLDA3 pleckstrin homology-like domain, family A, member 3 0.0136079
QSOX1 quiescin Q6 sulfhydryl oxidase 1 0.0136042
EP400 E1A binding protein p400 0.0136004
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.0134777
PRR14L proline rich 14-like 0.0134754
ACLY ATP citrate lyase 0.0134704
STAU1 staufen double-stranded RNA binding protein 1 0.013418
KMT2A lysine (K)-specific methyltransferase 2A 0.0133924
JAK1 Janus kinase 1 0.013353
DOK7 docking protein 7 0.0132715
OGA O-GlcNAcase 0.0132468
ATXN2 ataxin 2 0.0132438
WIPI1 WD repeat domain, phosphoinositide interacting 1 0.0131372
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 0.0131337
STARD10 StAR-related lipid transfer (START) domain containing 10 0.0131308
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0131108
RALY RALY heterogeneous nuclear ribonucleoprotein 0.0131043
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.0129952
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0129349
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) 0.0129119
PXDN peroxidasin 0.0129062
VAV2 vav 2 guanine nucleotide exchange factor 0.0129003
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.0128888
RBM39 RNA binding motif protein 39 0.0128606
RAB11FIP3 RAB11 family interacting protein 3 (class II) 0.0128409
TBCD tubulin folding cofactor D 0.0128353
AGO2 argonaute RISC catalytic component 2 0.012792
FNDC3A fibronectin type III domain containing 3A 0.0127776
RPL19 ribosomal protein L19 0.0127745
USP3 ubiquitin specific peptidase 3 0.0127015
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.0127005
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like 0.0126958
CA4 carbonic anhydrase IV 0.012695
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 0.0126776
AHNAK2 AHNAK nucleoprotein 2 0.0126611
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0126552
GAB2 GRB2-associated binding protein 2 0.0126524
POMT2 protein-O-mannosyltransferase 2 0.0126399
PRKD2 protein kinase D2 0.0126386
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0126323
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.0126272
SELENOS selenoprotein S 0.0125758
ASXL2 additional sex combs like transcriptional regulator 2 0.0125441
SON SON DNA binding protein 0.0125432
PTPRF protein tyrosine phosphatase, receptor type, F 0.0125126
BAZ2A bromodomain adjacent to zinc finger domain, 2A 0.0125001
RHOQ ras homolog family member Q 0.0124413
TGFB1 transforming growth factor, beta 1 0.0124189
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 0.0124063
HOOK2 hook microtubule-tethering protein 2 0.0123897
BATF basic leucine zipper transcription factor, ATF-like 0.0123872
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.0123862
WDFY2 WD repeat and FYVE domain containing 2 0.0123853
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.0123718
AK1 adenylate kinase 1 0.0123619
HMOX1 heme oxygenase 1 0.0123307
GABPB2 GA binding protein transcription factor, beta subunit 2 0.0123286
PSME4 proteasome (prosome, macropain) activator subunit 4 0.0122908
CCT7 chaperonin containing TCP1, subunit 7 (eta) 0.0122405
PLCG1 phospholipase C, gamma 1 0.0122373
CAPN2 calpain 2, (m/II) large subunit 0.0122124
INO80 INO80 complex subunit 0.0122051
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 0.0121668
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 0.0121109
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 0.0121052
ACACA acetyl-CoA carboxylase alpha 0.012103
PKN1 protein kinase N1 0.0120536
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.0120333
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.012013
PYGB phosphorylase, glycogen; brain 0.0119889
AKAP13 A kinase (PRKA) anchor protein 13 0.0119491
KLHDC10 kelch domain containing 10 0.0119403
UBN1 ubinuclein 1 0.0119398
NUP153 nucleoporin 153kDa 0.0119259
TMEM135 transmembrane protein 135 0.0119257
PPP1R13B protein phosphatase 1, regulatory subunit 13B 0.0119201
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.0119066
ENAH enabled homolog (Drosophila) 0.0119057
RPS6 ribosomal protein S6 0.01187
TBX2 T-box 2 0.0118345
RHOD ras homolog family member D 0.0118217
PMP22 peripheral myelin protein 22 0.0118076
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 0.0117913
SLC31A1 solute carrier family 31 (copper transporter), member 1 0.0117867
SETD5 SET domain containing 5 0.0117837
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) 0.0117729
GLG1 golgi glycoprotein 1 0.0117575
S100P S100 calcium binding protein P 0.011755
RAB22A RAB22A, member RAS oncogene family 0.011729
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 0.0117117
WBP2 WW domain binding protein 2 0.0116952
NCOA1 nuclear receptor coactivator 1 0.0116617
ARL8B ADP-ribosylation factor-like 8B 0.0116595
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.0116244
SOS2 son of sevenless homolog 2 (Drosophila) 0.0116135
PRXL2A peroxiredoxin like 2A 0.0115852
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 0.0115571
GOLGA8B golgin A8 family, member B 0.0115061
ATF4 activating transcription factor 4 0.0114968
BLVRB biliverdin reductase B 0.0114864
RNF149 ring finger protein 149 0.0114829
RUNX1 runt-related transcription factor 1 0.0114551
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.0114188
ZNF280D zinc finger protein 280D 0.0114135
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 0.0113789
XPC xeroderma pigmentosum, complementation group C 0.0113246
MECP2 methyl CpG binding protein 2 0.0113237
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 0.0113198
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0112941
TANK TRAF family member-associated NFKB activator 0.0112911
ZNF75A zinc finger protein 75a 0.0112896
MCL1 myeloid cell leukemia 1 0.0112479
TBC1D22A TBC1 domain family, member 22A 0.011244
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.0112426
RPL18A ribosomal protein L18a 0.0111854
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.011163
GOLGA4 golgin A4 0.0111528
OTUD7B OTU deubiquitinase 7B 0.0111504
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.0111395
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 0.0110754
ASS1 argininosuccinate synthase 1 0.0110698
SSH2 slingshot protein phosphatase 2 0.0110092
CDYL chromodomain protein, Y-like 0.0110085
PACS2 phosphofurin acidic cluster sorting protein 2 0.0109751
SEC16A SEC16 homolog A (S. cerevisiae) 0.0109182
LMCD1 LIM and cysteine-rich domains 1 0.0109152
ATP9B ATPase, class II, type 9B 0.0109106
SPART spartin 0.0108777
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.0108535
ARF1 ADP-ribosylation factor 1 0.0108373
MGST1 microsomal glutathione S-transferase 1 0.010835
DTX3L deltex 3 like, E3 ubiquitin ligase 0.0108268
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.0108011
BOD1L1 biorientation of chromosomes in cell division 1-like 1 0.0107879
FHIT fragile histidine triad 0.0107771
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0107769
RANBP2 RAN binding protein 2 0.0107487
RPS29 ribosomal protein S29 0.0107328
RPS8 ribosomal protein S8 0.0107191
MIA2 melanoma inhibitory activity 2 0.0106751
EPPK1 epiplakin 1 0.0106377
FAM120A family with sequence similarity 120A 0.0106349
SLC38A1 solute carrier family 38, member 1 0.010633
DLG1 discs, large homolog 1 (Drosophila) 0.010623
MFGE8 milk fat globule-EGF factor 8 protein 0.0106088
UBE2R2 ubiquitin-conjugating enzyme E2R 2 0.0105877
MAP3K2 mitogen-activated protein kinase kinase kinase 2 0.0105852
COX19 COX19 cytochrome c oxidase assembly factor 0.0105842
TRIOBP TRIO and F-actin binding protein 0.0105692
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 0.0105674
NBAS neuroblastoma amplified sequence 0.0105671
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.0105533
METAP2 methionyl aminopeptidase 2 0.0105521
ACBD3 acyl-CoA binding domain containing 3 0.0105394
CENPB centromere protein B, 80kDa 0.0105013
ITSN2 intersectin 2 0.0104957
DGKZ diacylglycerol kinase, zeta 0.0104946
NTN4 netrin 4 0.010493
CEP350 centrosomal protein 350kDa 0.0104785
CUL4A cullin 4A 0.0104754
EP300 E1A binding protein p300 0.0104496
BBX bobby sox homolog (Drosophila) 0.0104246
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.0104206
AP3D1 adaptor-related protein complex 3, delta 1 subunit 0.0103906
ZNF800 zinc finger protein 800 0.0103632
RBBP6 retinoblastoma binding protein 6 0.0103005
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 0.0102911
DNPEP aspartyl aminopeptidase 0.0102525
CARM1 coactivator-associated arginine methyltransferase 1 0.0102509
TCF12 transcription factor 12 0.0102319
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0102258
IPO4 importin 4 0.0101558
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.010143
USP54 ubiquitin specific peptidase 54 0.0101295
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 0.0101074
SCARB1 scavenger receptor class B, member 1 0.010086
NBEAL1 neurobeachin-like 1 0.0100848
TANGO2 transport and golgi organization 2 homolog (Drosophila) 0.0100709
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 0.0100657
AOPEP aminopeptidase O (putative) 0.010052
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0100114
LRRC58 leucine rich repeat containing 58 0.00998411
YAF2 YY1 associated factor 2 0.00997126
VEGFA vascular endothelial growth factor A 0.00996835
SAMD12 sterile alpha motif domain containing 12 0.00994372
ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif, 17 0.00994051
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 0.00993355
MBNL2 muscleblind-like splicing regulator 2 0.00992548
RPL7A ribosomal protein L7a 0.00990216
UNK unkempt family zinc finger 0.00990082
CDYL2 chromodomain protein, Y-like 2 0.00989343
ELOVL6 ELOVL fatty acid elongase 6 0.00988508
S100A6 S100 calcium binding protein A6 0.00988125
TRIM27 tripartite motif containing 27 0.00986897
IGF2R insulin-like growth factor 2 receptor 0.00986212
SEC23A Sec23 homolog A (S. cerevisiae) 0.00986199
ZBTB40 zinc finger and BTB domain containing 40 0.00986197
CSNK2A2 casein kinase 2, alpha prime polypeptide 0.00986006
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa 0.00984924
RAB2A RAB2A, member RAS oncogene family 0.00982603
FBXW11 F-box and WD repeat domain containing 11 0.00982186
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.00982089

decreased expression

Symbol Name Standardized Value
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.185294
ESR1 estrogen receptor 1 -0.161272
GFRA1 GDNF family receptor alpha 1 -0.143073
WWOX WW domain containing oxidoreductase -0.132882
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.1255
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.12438
PARD6B par-6 family cell polarity regulator beta -0.118529
GATA3 GATA binding protein 3 -0.106125
EVL Enah/Vasp-like -0.105143
BCAS3 breast carcinoma amplified sequence 3 -0.10142
SYTL2 synaptotagmin-like 2 -0.100695
SULF2 sulfatase 2 -0.095213
AGR2 anterior gradient 2 -0.0890615
EMP2 epithelial membrane protein 2 -0.0834601
JARID2 jumonji, AT rich interactive domain 2 -0.0810045
MALRD1 MAM and LDL receptor class A domain containing 1 -0.0792014
KRT8 keratin 8, type II -0.075662
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.0720695
ERBB4 erb-b2 receptor tyrosine kinase 4 -0.0706355
GPC6 glypican 6 -0.0691319
MKI67 marker of proliferation Ki-67 -0.0681125
PLXDC2 plexin domain containing 2 -0.067521
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 -0.0640948
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.0608392
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 -0.0603525
THSD4 thrombospondin, type I, domain containing 4 -0.0577504
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.0577363
CNKSR3 CNKSR family member 3 -0.0557451
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) -0.0551231
IGF1R insulin-like growth factor 1 receptor -0.0547386
CALCR calcitonin receptor -0.0530575
KRT19 keratin 19, type I -0.0529291
LRP1B low density lipoprotein receptor-related protein 1B -0.0502873
ATAD2 ATPase family, AAA domain containing 2 -0.0492708
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.047756
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0466983
RAD51B RAD51 paralog B -0.0465081
FMN1 formin 1 -0.0464459
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 -0.0443106
NRG3 neuregulin 3 -0.0438335
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 -0.043642
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0421399
TRIM33 tripartite motif containing 33 -0.042064
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0412577
PBX1 pre-B-cell leukemia homeobox 1 -0.0400524
ELP2 elongator acetyltransferase complex subunit 2 -0.0394925
NT5C2 5'-nucleotidase, cytosolic II -0.039187
DCDC2 doublecortin domain containing 2 -0.0384215
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -0.0383274
MACROD2 MACRO domain containing 2 -0.0383227
BPTF bromodomain PHD finger transcription factor -0.0363567
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0357447
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein -0.0356503
BCL2 B-cell CLL/lymphoma 2 -0.0355447
PRR11 proline rich 11 -0.0351233
TET2 tet methylcytosine dioxygenase 2 -0.0350988
GNAS GNAS complex locus -0.0350883
CLDN3 claudin 3 -0.0338592
ZMYND8 zinc finger, MYND-type containing 8 -0.0318913
GNA14 guanine nucleotide binding protein (G protein), alpha 14 -0.031153
HIP1 huntingtin interacting protein 1 -0.0311382
NCAM2 neural cell adhesion molecule 2 -0.0308285
NCKAP5 NCK-associated protein 5 -0.0308143
TMEM164 transmembrane protein 164 -0.0307275
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.0304313
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) -0.0297568
ABHD2 abhydrolase domain containing 2 -0.0295743
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.0292162
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa -0.0290182
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -0.0287738
CALR calreticulin -0.0286321
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -0.0280476
TMCC1 transmembrane and coiled-coil domain family 1 -0.0277538
ZMYM2 zinc finger, MYM-type 2 -0.0276389
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.0274286
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -0.0272468
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 -0.0270237
XPO1 exportin 1 -0.0269937
ATRNL1 attractin-like 1 -0.0269266
FAF1 Fas (TNFRSF6) associated factor 1 -0.0268872
TUBA1B tubulin, alpha 1b -0.0265019
TUBD1 tubulin, delta 1 -0.0264906
SRPK2 SRSF protein kinase 2 -0.0264686
DOCK1 dedicator of cytokinesis 1 -0.0263255
KAT6B K(lysine) acetyltransferase 6B -0.0260535
PBX3 pre-B-cell leukemia homeobox 3 -0.0258804
C1ORF21 chromosome 1 open reading frame 21 -0.0258382
UGDH UDP-glucose 6-dehydrogenase -0.0257673
LY6E lymphocyte antigen 6 complex, locus E -0.0254885
PKP4 plakophilin 4 -0.0252672
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.0252306
CENPP centromere protein P -0.0252097
CYRIB CYFIP related Rac1 interactor B -0.0250572
DNMBP dynamin binding protein -0.025033
STARD13 StAR-related lipid transfer (START) domain containing 13 -0.024747
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.0247333
NHSL1 NHS-like 1 -0.0247025
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.0246389
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.0245888
ACTN4 actinin, alpha 4 -0.0243086
MYOF myoferlin -0.024055
MAST4 microtubule associated serine/threonine kinase family member 4 -0.0239871
UBTF upstream binding transcription factor, RNA polymerase I -0.0239313
CCDC170 coiled-coil domain containing 170 -0.0239235
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -0.0238657
TMEM64 transmembrane protein 64 -0.0238587
CREBBP CREB binding protein -0.0236222
GRHL2 grainyhead-like 2 (Drosophila) -0.0231417
BRCA2 breast cancer 2, early onset -0.0229825
SMYD3 SET and MYND domain containing 3 -0.0226577
FBXL17 F-box and leucine-rich repeat protein 17 -0.0224891
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta -0.0223033
FREM2 FRAS1 related extracellular matrix protein 2 -0.0222841
FANCC Fanconi anemia, complementation group C -0.0222306
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -0.022222
CA12 carbonic anhydrase XII -0.0221397
LRIF1 ligand dependent nuclear receptor interacting factor 1 -0.0220168
FCHSD2 FCH and double SH3 domains 2 -0.0218867
LARP4B La ribonucleoprotein domain family, member 4B -0.0217855
HMCN1 hemicentin 1 -0.0216912
SDK1 sidekick cell adhesion molecule 1 -0.0216324
BCAS1 breast carcinoma amplified sequence 1 -0.0215993
TMEM150C transmembrane protein 150C -0.0215803
PGR progesterone receptor -0.0215662
TPX2 TPX2, microtubule-associated -0.0215625
CUX1 cut-like homeobox 1 -0.0214748
SH3BP5 SH3-domain binding protein 5 (BTK-associated) -0.0214593
ADARB1 adenosine deaminase, RNA-specific, B1 -0.0214176
DIAPH2 diaphanous-related formin 2 -0.0214146
PCDH7 protocadherin 7 -0.0213064
BMP7 bone morphogenetic protein 7 -0.0206372
TRPS1 trichorhinophalangeal syndrome I -0.0205453
UTRN utrophin -0.0204902
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 -0.0204489
TRAPPC9 trafficking protein particle complex 9 -0.0203426
ARSG arylsulfatase G -0.0203035
FOXP1 forkhead box P1 -0.0202846
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.0200857
R3HDM1 R3H domain containing 1 -0.020026
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 -0.0199705
SPIDR scaffolding protein involved in DNA repair -0.0199223
MACF1 microtubule-actin crosslinking factor 1 -0.0199038
RNASE12 ribonuclease, RNase A family, 12 (non-active) -0.0195089
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0194151
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -0.0193351
RERE arginine-glutamic acid dipeptide (RE) repeats -0.019198
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 -0.0191314
RHOBTB3 Rho-related BTB domain containing 3 -0.0188205
NPAS3 neuronal PAS domain protein 3 -0.0187349
GREB1L growth regulation by estrogen in breast cancer-like -0.0187136
THADA thyroid adenoma associated -0.0185973
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.0185135
PHACTR4 phosphatase and actin regulator 4 -0.0185086
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -0.0184602
HLTF helicase-like transcription factor -0.018441
HMGB1 high mobility group box 1 -0.0184134
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -0.0183863
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -0.0183686
RPL32 ribosomal protein L32 -0.0183325
MTDH metadherin -0.0182738
ARB2A ARB2 cotranscriptional regulator A -0.0182163
CTNNA3 catenin (cadherin-associated protein), alpha 3 -0.0181763
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.018176
KMT5B lysine methyltransferase 5B -0.0181473
PEAK1 pseudopodium-enriched atypical kinase 1 -0.0181471
AKAP9 A kinase (PRKA) anchor protein 9 -0.0181407
BLM Bloom syndrome, RecQ helicase-like -0.017896
RBL1 retinoblastoma-like 1 -0.0178392
BRCA1 breast cancer 1, early onset -0.0176969
DERL1 derlin 1 -0.017686
SRSF10 serine/arginine-rich splicing factor 10 -0.0175461
FANCI Fanconi anemia, complementation group I -0.0174859
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.0174827
FANCA Fanconi anemia, complementation group A -0.0173861
ITGB5 integrin, beta 5 -0.0172974
PTPRA protein tyrosine phosphatase, receptor type, A -0.0172974
PFN1 profilin 1 -0.0172403
BCL2L1 BCL2-like 1 -0.0170463
SKA2 spindle and kinetochore associated complex subunit 2 -0.0169733
DNM2 dynamin 2 -0.0169299
EPN2 epsin 2 -0.0168557
MBNL1 muscleblind-like splicing regulator 1 -0.0167665
BRI3BP BRI3 binding protein -0.0166917
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase -0.0166765
CAMKMT calmodulin-lysine N-methyltransferase -0.0166177
FRMD5 FERM domain containing 5 -0.0165139
TPR translocated promoter region, nuclear basket protein -0.0164999
TIAM1 T-cell lymphoma invasion and metastasis 1 -0.016489
GRB2 growth factor receptor-bound protein 2 -0.0163775
TMED8 transmembrane emp24 protein transport domain containing 8 -0.0163369
KRT18 keratin 18, type I -0.0163336
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -0.016294
NCOA2 nuclear receptor coactivator 2 -0.0162742
TMPO thymopoietin -0.0161795
HNRNPR heterogeneous nuclear ribonucleoprotein R -0.016163
OSBPL10 oxysterol binding protein-like 10 -0.0161229
NCAPG2 non-SMC condensin II complex, subunit G2 -0.016007
GPHN gephyrin -0.0159808
COX6C cytochrome c oxidase subunit VIc -0.0159313
SIAH2 siah E3 ubiquitin protein ligase 2 -0.0159073
MSH2 mutS homolog 2 -0.0158654
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0158355
PDS5A PDS5 cohesin associated factor A -0.0158342
TOP2B topoisomerase (DNA) II beta 180kDa -0.0157439
TTLL10 tubulin tyrosine ligase-like family member 10 -0.0157218
CA2 carbonic anhydrase II -0.0157038
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.01567
RNF168 ring finger protein 168, E3 ubiquitin protein ligase -0.0156206
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.0155764
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -0.0155139
AAGAB alpha- and gamma-adaptin binding protein -0.0154827
NOP58 NOP58 ribonucleoprotein -0.0154598
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0154315
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -0.0152955
LMX1B LIM homeobox transcription factor 1, beta -0.0152808
MRTFB myocardin related transcription factor B -0.015273
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0151567
DTNB dystrobrevin, beta -0.0151036
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0150893
SCAI suppressor of cancer cell invasion -0.0150628
WDHD1 WD repeat and HMG-box DNA binding protein 1 -0.0150579
DMXL1 Dmx-like 1 -0.0150414
SCAF11 SR-related CTD-associated factor 11 -0.0150399
TMEM178B transmembrane protein 178B -0.015008
SMIM44 small integral membrane protein 44 -0.0149811
CTNND2 catenin (cadherin-associated protein), delta 2 -0.0149737
SF3B3 splicing factor 3b, subunit 3, 130kDa -0.0149621
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -0.0149233
PEX14 peroxisomal biogenesis factor 14 -0.0148896
CADM1 cell adhesion molecule 1 -0.0148059
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0148045
SASH1 SAM and SH3 domain containing 1 -0.0147736
CD81 CD81 molecule -0.0147687
EXOC6 exocyst complex component 6 -0.0147468
KANSL1 KAT8 regulatory NSL complex subunit 1 -0.0146909
OXR1 oxidation resistance 1 -0.0146683
EPHA4 EPH receptor A4 -0.0145865
GMDS GDP-mannose 4,6-dehydratase -0.0145612
PTTG1IP pituitary tumor-transforming 1 interacting protein -0.0145557
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -0.0145168
ZNF718 zinc finger protein 718 -0.0145091
WWC1 WW and C2 domain containing 1 -0.0144809
CDC42SE2 CDC42 small effector 2 -0.0144788
SPTSSB serine palmitoyltransferase, small subunit B -0.0144726
POTEF POTE ankyrin domain family, member F -0.0143966
BSG basigin (Ok blood group) -0.014391
NMD3 NMD3 ribosome export adaptor -0.0143631
AP1G1 adaptor-related protein complex 1, gamma 1 subunit -0.0143353
EXOC4 exocyst complex component 4 -0.0143239
RNASE3 ribonuclease, RNase A family, 3 -0.0142997
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.0142694
GREB1 growth regulation by estrogen in breast cancer 1 -0.0142636
MICU2 mitochondrial calcium uptake 2 -0.0141653
GPATCH2 G patch domain containing 2 -0.0141235
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0140508
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.0140432
COL4A5 collagen, type IV, alpha 5 -0.0140333
ITGB4 integrin, beta 4 -0.0139734
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 -0.0137991
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 -0.013722
SUGP2 SURP and G patch domain containing 2 -0.0136662
EZR ezrin -0.0136474
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -0.0136268
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.0136071
ZMYND11 zinc finger, MYND-type containing 11 -0.0135533
FOXRED2 FAD-dependent oxidoreductase domain containing 2 -0.0134862
BBLN bublin coiled coil protein -0.01345
TENT2 terminal nucleotidyltransferase 2 -0.0134002
FAM168A family with sequence similarity 168, member A -0.0133956
SRSF4 serine/arginine-rich splicing factor 4 -0.0133956
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 -0.0133863
MAVS mitochondrial antiviral signaling protein -0.0133428
ATXN7L1 ataxin 7-like 1 -0.0133001
MED12 mediator complex subunit 12 -0.0132701
NHP2 NHP2 ribonucleoprotein -0.0132668
ZZZ3 zinc finger, ZZ-type containing 3 -0.0131962
HNRNPF heterogeneous nuclear ribonucleoprotein F -0.0131825
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -0.0131636
VANGL1 VANGL planar cell polarity protein 1 -0.0131621
FANCD2 Fanconi anemia, complementation group D2 -0.0131609
ETF1 eukaryotic translation termination factor 1 -0.0131308
SSBP3 single stranded DNA binding protein 3 -0.0131223
FAM222B family with sequence similarity 222, member B -0.0130863
ZNF260 zinc finger protein 260 -0.0130837
PLEKHA6 pleckstrin homology domain containing, family A member 6 -0.013075
INTS2 integrator complex subunit 2 -0.0130672
ERBB3 erb-b2 receptor tyrosine kinase 3 -0.013066
PTBP1 polypyrimidine tract binding protein 1 -0.0130406
CLU clusterin -0.0130321
MYH9 myosin, heavy chain 9, non-muscle -0.0130305
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -0.0130285
PDE8A phosphodiesterase 8A -0.0130033
LRP10 low density lipoprotein receptor-related protein 10 -0.0129447
KDM3B lysine (K)-specific demethylase 3B -0.01286
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.012834
MAN1A2 mannosidase, alpha, class 1A, member 2 -0.0127992
PPP1R21 protein phosphatase 1, regulatory subunit 21 -0.0127906
PRSS23 protease, serine, 23 -0.0127844
THOC7 THO complex 7 -0.0127461
VEZT vezatin, adherens junctions transmembrane protein -0.0126899
IGFBP4 insulin-like growth factor binding protein 4 -0.0126744
FXYD3 FXYD domain containing ion transport regulator 3 -0.0125786
SACK1B scaffolding CK1 anchoring protein B -0.0125488
POGZ pogo transposable element with ZNF domain -0.0125464
JUP junction plakoglobin -0.0125254
STXBP5 syntaxin binding protein 5 (tomosyn) -0.0124835
FBP1 fructose-1,6-bisphosphatase 1 -0.0124773
LIN52 lin-52 DREAM MuvB core complex component -0.0124627
RAB31 RAB31, member RAS oncogene family -0.0124289
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -0.0124137
SPDEF SAM pointed domain containing ETS transcription factor -0.0124067
ARSD arylsulfatase D -0.01238
ZNF566 zinc finger protein 566 -0.01227
SNX4 sorting nexin 4 -0.012256
OCIAD1 OCIA domain containing 1 -0.0122535
MCM4 minichromosome maintenance complex component 4 -0.0122308
BASP1 brain abundant, membrane attached signal protein 1 -0.012222
SHROOM2 shroom family member 2 -0.0122195
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.012198
LYPD6B LY6/PLAUR domain containing 6B -0.0121796
TBC1D5 TBC1 domain family, member 5 -0.0121516
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0121266
TNRC18 trinucleotide repeat containing 18 -0.0121233
CST3 cystatin C -0.0121078
DCAF10 DDB1 and CUL4 associated factor 10 -0.0121015
PGCKA1 PDCD10 and GCKIII kinases associated 1 -0.01208
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -0.01206
NUP205 nucleoporin 205kDa -0.0120142
ENO1 enolase 1, (alpha) -0.0119596
FAM13B family with sequence similarity 13, member B -0.0119335
SLMAP sarcolemma associated protein -0.011914
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.0119111
HSF1 heat shock transcription factor 1 -0.0118673
TASP1 taspase, threonine aspartase, 1 -0.0118598
TPM3 tropomyosin 3 -0.0118421
TEX2 testis expressed 2 -0.0118395
DCPH1 damage control phosphatase 1 -0.0118289
SPATA7 spermatogenesis associated 7 -0.0118202
TM9SF3 transmembrane 9 superfamily member 3 -0.0117756
KSR2 kinase suppressor of ras 2 -0.0117612
ARHGAP24 Rho GTPase activating protein 24 -0.0117161
NPEPPS aminopeptidase puromycin sensitive -0.011709
USP15 ubiquitin specific peptidase 15 -0.0117033
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 -0.0116406
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -0.0116049
JAK2 Janus kinase 2 -0.0115736
TMEM63A transmembrane protein 63A -0.0115571
RTN4RL1 reticulon 4 receptor-like 1 -0.0115406
CENPE centromere protein E, 312kDa -0.0114856
DLC1 DLC1 Rho GTPase activating protein -0.0114429
NCAPD2 non-SMC condensin I complex, subunit D2 -0.0114262
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.0114255
WDR59 WD repeat domain 59 -0.0114247
NTN1 netrin 1 -0.0113929
HDAC8 histone deacetylase 8 -0.0113873
CBX5 chromobox homolog 5 -0.0113688
SNX29 sorting nexin 29 -0.0113329
ENOX2 ecto-NOX disulfide-thiol exchanger 2 -0.0113124
TOM1L2 target of myb1-like 2 (chicken) -0.0112934
FTSJ3 FtsJ homolog 3 (E. coli) -0.0112899
MRPS21 mitochondrial ribosomal protein S21 -0.0112727
ASF1B anti-silencing function 1B histone chaperone -0.0112569
MARCHF6 membrane associated ring-CH-type finger 6 -0.0112186
ZCCHC17 zinc finger, CCHC domain containing 17 -0.0111995
YAP1 Yes-associated protein 1 -0.0111992
LDOC1 leucine zipper, down-regulated in cancer 1 -0.0111872
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.0111274
REPS1 RALBP1 associated Eps domain containing 1 -0.0111186
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -0.0110431
C21ORF58 chromosome 21 open reading frame 58 -0.0109914
APOD apolipoprotein D -0.0109671
KNTC1 kinetochore associated 1 -0.0109629
PRMT9 protein arginine methyltransferase 9 -0.0109584
ABI2 abl-interactor 2 -0.0109278
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.0109092
HAT1 histone acetyltransferase 1 -0.0109007
SMC4 structural maintenance of chromosomes 4 -0.0108806
RBMX RNA binding motif protein, X-linked -0.0108595
ZBTB25 zinc finger and BTB domain containing 25 -0.0108572
ALMS1 Alstrom syndrome protein 1 -0.0108199
ZRANB3 zinc finger, RAN-binding domain containing 3 -0.0108136
SNX17 sorting nexin 17 -0.0107991
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -0.010791
TUBB4B tubulin, beta 4B class IVb -0.0107809
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -0.0107652
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -0.0107576
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit -0.0107495
PHC3 polyhomeotic homolog 3 (Drosophila) -0.010707
TMEM205 transmembrane protein 205 -0.0106885
MYO6 myosin VI -0.0106862
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -0.0106803
RANBP9 RAN binding protein 9 -0.0106743
RPL30 ribosomal protein L30 -0.010643
YLPM1 YLP motif containing 1 -0.0106348
PARD3 par-3 family cell polarity regulator -0.010634
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0106296
POLK polymerase (DNA directed) kappa -0.0106259
ZNF124 zinc finger protein 124 -0.0105916
AP2M1 adaptor-related protein complex 2, mu 1 subunit -0.0105864
THRB thyroid hormone receptor, beta -0.010571
SLC30A9 solute carrier family 30 (zinc transporter), member 9 -0.0105579
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -0.0105367
SNX6 sorting nexin 6 -0.0105116
PARN poly(A)-specific ribonuclease -0.0104882
HS3ST5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5 -0.0104854
TPM4 tropomyosin 4 -0.0104616
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1 -0.0104555
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 -0.0104396
HELLS helicase, lymphoid-specific -0.0104118
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit -0.0103986
UBE2K ubiquitin-conjugating enzyme E2K -0.0103977
SF3A3 splicing factor 3a, subunit 3, 60kDa -0.0103805
GET1 guided entry of tail-anchored proteins factor 1 -0.0103776
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha -0.0103704
RHPN2 rhophilin, Rho GTPase binding protein 2 -0.0103655
PRPF3 pre-mRNA processing factor 3 -0.0103654
CD9 CD9 molecule -0.0103469
ASTN2 astrotactin 2 -0.0103348
RNF130 ring finger protein 130 -0.010314
RERG RAS-like, estrogen-regulated, growth inhibitor -0.0103119
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial -0.0103089
RBM6 RNA binding motif protein 6 -0.0102927
CUL5 cullin 5 -0.0102841
SFXN5 sideroflexin 5 -0.0102735
TPD52 tumor protein D52 -0.01022
LSG1 large 60S subunit nuclear export GTPase 1 -0.0102098
EYA3 EYA transcriptional coactivator and phosphatase 3 -0.0102036
TTF2 transcription termination factor, RNA polymerase II -0.0101673
CD59 CD59 molecule, complement regulatory protein -0.0101364
YTHDC1 YTH domain containing 1 -0.0101241
SAPCD2 suppressor APC domain containing 2 -0.0101041
SIL1 SIL1 nucleotide exchange factor -0.0100898
DENND1B DENN/MADD domain containing 1B -0.0100829
FHIP1A FHF complex subunit HOOK interacting protein 1A -0.0100828
UBE2O ubiquitin-conjugating enzyme E2O -0.0100778
SLC44A2 solute carrier family 44 (choline transporter), member 2 -0.0100725
LONRF2 LON peptidase N-terminal domain and ring finger 2 -0.0100602
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2 -0.0100524
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 -0.0100524
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -0.0100373
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3 -0.0100327
ABHD18 abhydrolase domain containing 18 -0.0100142
SIDT1 SID1 transmembrane family, member 1 -0.0100113
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) -0.00999835
UBE3A ubiquitin protein ligase E3A -0.00997777
SPTBN2 spectrin, beta, non-erythrocytic 2 -0.00996019
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa -0.00992972
CALML5 calmodulin-like 5 -0.00988418
SYPL1 synaptophysin-like 1 -0.00987974
FAM193A family with sequence similarity 193, member A -0.00987866
VTA1 vesicle (multivesicular body) trafficking 1 -0.00987087
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.00987071
GALC galactosylceramidase -0.00986774
EIF3B eukaryotic translation initiation factor 3, subunit B -0.00984188
ERMP1 endoplasmic reticulum metallopeptidase 1 -0.00984094
BICRAL BICRA like chromatin remodeling complex associated protein -0.0098285
NXNL2 nucleoredoxin-like 2 -0.00982827
VIRMA vir like m6A methyltransferase associated -0.00981908
METTL16 methyltransferase like 16 -0.00981707
ARHGAP18 Rho GTPase activating protein 18 -0.00980793
SLC39A11 solute carrier family 39, member 11 -0.00980724
REV1 REV1, polymerase (DNA directed) -0.0098032
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33 -0.00979436
TBK1 TANK-binding kinase 1 -0.00979318
ANLN anillin, actin binding protein -0.00978484
GINS2 GINS complex subunit 2 (Psf2 homolog) -0.00977615
BICD1 bicaudal D homolog 1 (Drosophila) -0.00977364
TRIM28 tripartite motif containing 28 -0.00976978
LMBR1 limb development membrane protein 1 -0.00972993
ACSL3 acyl-CoA synthetase long-chain family member 3 -0.00971236
MAML3 mastermind-like 3 (Drosophila) -0.00970008
ACTR3C ARP3 actin-related protein 3 homolog C (yeast) -0.00969868
SEPTIN6 septin 6 -0.00969141
UBA1 ubiquitin-like modifier activating enzyme 1 -0.00969037
EDRF1 erythroid differentiation regulatory factor 1 -0.00965908
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 -0.00965665
IFI6 interferon, alpha-inducible protein 6 -0.00965366
C9ORF78 chromosome 9 open reading frame 78 -0.00963997
PDZRN3 PDZ domain containing ring finger 3 -0.00963022
ITGB6 integrin, beta 6 -0.00962307
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 -0.00960912
GCN1 GCN1 activator of EIF2AK4 -0.00959871
NUP160 nucleoporin 160kDa -0.00959255
MAPKAP1 mitogen-activated protein kinase associated protein 1 -0.00957722
BTBD9 BTB (POZ) domain containing 9 -0.00955786
IFT43 intraflagellar transport 43 -0.00955292
C2CD5 C2 calcium-dependent domain containing 5 -0.00954837
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -0.00954463
PRRT3 proline-rich transmembrane protein 3 -0.00953806
FTCDNL1 formiminotransferase cyclodeaminase N-terminal like -0.00953753
MUC16 mucin 16, cell surface associated -0.00953318
VKORC1 vitamin K epoxide reductase complex, subunit 1 -0.00952881
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 -0.00950515
SCRN1 secernin 1 -0.00950329
SGO2 shugoshin 2 -0.00949148
AMBRA1 autophagy/beclin-1 regulator 1 -0.0094519
DIAPH3 diaphanous-related formin 3 -0.00944383
LAMA5 laminin, alpha 5 -0.00944042
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 -0.00943872
CLSPN claspin -0.00941101