MCF7_Obatoclax Mesylate_100nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description Obatoclax Mesylate 100nM perturbation in MCF7 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the MCF7_Obatoclax Mesylate_100nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
PABPC1 poly(A) binding protein, cytoplasmic 1 0.15921
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.121065
GATA3 GATA binding protein 3 0.112909
CSDE1 cold shock domain containing E1, RNA-binding 0.101543
EEF2 eukaryotic translation elongation factor 2 0.101246
USP32 ubiquitin specific peptidase 32 0.0898331
MALRD1 MAM and LDL receptor class A domain containing 1 0.0867149
POTEF POTE ankyrin domain family, member F 0.0818784
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.0763565
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0733028
EVL Enah/Vasp-like 0.073212
RPS2 ribosomal protein S2 0.0715825
RPS8 ribosomal protein S8 0.0705159
KRT18 keratin 18, type I 0.0688447
MED13 mediator complex subunit 13 0.0676519
CCND1 cyclin D1 0.0651165
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.0630159
RPL12 ribosomal protein L12 0.0623883
RPS6 ribosomal protein S6 0.0622689
BPTF bromodomain PHD finger transcription factor 0.0586962
SMIM14 small integral membrane protein 14 0.0580547
CTNND2 catenin (cadherin-associated protein), delta 2 0.0575419
RPL15 ribosomal protein L15 0.0565379
GREB1 growth regulation by estrogen in breast cancer 1 0.0556397
RPS3 ribosomal protein S3 0.0529556
TTC3 tetratricopeptide repeat domain 3 0.0526978
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.0525331
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.0515169
NRP1 neuropilin 1 0.0514701
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0501148
KMT2A lysine (K)-specific methyltransferase 2A 0.0494538
LGALS3 lectin, galactoside-binding, soluble, 3 0.0471091
TPT1 tumor protein, translationally-controlled 1 0.0467358
BCL2L1 BCL2-like 1 0.0464274
ENO1 enolase 1, (alpha) 0.0447145
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.0432836
DSPP dentin sialophosphoprotein 0.0422125
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.0412615
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.0411889
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.040621
ZFP36L2 ZFP36 ring finger protein-like 2 0.040482
RPL13A ribosomal protein L13a 0.0403665
SEPTIN9 septin 9 0.0401557
THSD4 thrombospondin, type I, domain containing 4 0.0399703
EIF4B eukaryotic translation initiation factor 4B 0.039389
CBX5 chromobox homolog 5 0.0393048
SMYD3 SET and MYND domain containing 3 0.0393005
PTPRK protein tyrosine phosphatase, receptor type, K 0.0392581
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.0385116
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.0379057
MRPL13 mitochondrial ribosomal protein L13 0.0378442
TMEM150C transmembrane protein 150C 0.0376608
TUBB tubulin, beta class I 0.0376512
ZNF217 zinc finger protein 217 0.0374329
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0373225
LOC112694756 uncharaterized LOC112694756 0.0369179
LRRC58 leucine rich repeat containing 58 0.0365461
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 0.0364284
GNAS GNAS complex locus 0.0363232
DAAM1 dishevelled associated activator of morphogenesis 1 0.0362646
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0361208
NRCAM neuronal cell adhesion molecule 0.0358557
RPS5 ribosomal protein S5 0.0348599
PRR14L proline rich 14-like 0.034767
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.0347644
RAP1A RAP1A, member of RAS oncogene family 0.0347203
ATP5F1B ATP synthase F1 subunit beta 0.0346624
ARTN artemin 0.0346545
OSBPL10 oxysterol binding protein-like 10 0.0342452
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.0342153
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 0.0341214
NRIP1 nuclear receptor interacting protein 1 0.0340531
MUC16 mucin 16, cell surface associated 0.033822
PRRC2C proline-rich coiled-coil 2C 0.0337844
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.0337415
RPLP0 ribosomal protein, large, P0 0.033417
ZBTB11 zinc finger and BTB domain containing 11 0.033317
DEK DEK proto-oncogene 0.0332314
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.0332314
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.0326237
TACC1 transforming, acidic coiled-coil containing protein 1 0.0324691
SKIL SKI-like proto-oncogene 0.0320951
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0318378
RSL24D1 ribosomal L24 domain containing 1 0.0317553
KRT19 keratin 19, type I 0.0309756
MSI2 musashi RNA-binding protein 2 0.0308661
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.030739
RSL1D1 ribosomal L1 domain containing 1 0.0302739
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.029957
RACK1 receptor for activated C kinase 1 0.0298834
TAOK1 TAO kinase 1 0.0297126
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.029664
RPL18 ribosomal protein L18 0.0296618
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.029547
AGO2 argonaute RISC catalytic component 2 0.0295154
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0293682
FTH1 ferritin, heavy polypeptide 1 0.0291644
ACBD6 acyl-CoA binding domain containing 6 0.0291459
CAND1 cullin-associated and neddylation-dissociated 1 0.029129
FLNA filamin A, alpha 0.0286115
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0282823
GTF2I general transcription factor IIi 0.0282755
NAV1 neuron navigator 1 0.0282308
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) 0.0281891
TRIM37 tripartite motif containing 37 0.0279736
H3-3B H3.3 histone B 0.0277662
NINL ninein-like 0.0277171
PGR progesterone receptor 0.0276018
STC2 stanniocalcin 2 0.027488
RB1CC1 RB1-inducible coiled-coil 1 0.0274469
PKN2 protein kinase N2 0.0274453
RPS12 ribosomal protein S12 0.0270893
SERF2 small EDRK-rich factor 2 0.027029
RPL10A ribosomal protein L10a 0.0270083
IER3 immediate early response 3 0.0267466
BRCA2 breast cancer 2, early onset 0.0266969
NECAB1 N-terminal EF-hand calcium binding protein 1 0.0266297
PARD6B par-6 family cell polarity regulator beta 0.0265863
UBL4A ubiquitin-like 4A 0.0264561
RPL32 ribosomal protein L32 0.026452
KPNB1 karyopherin (importin) beta 1 0.0263705
TBC1D16 TBC1 domain family, member 16 0.0261785
CREBBP CREB binding protein 0.026033
TNPO3 transportin 3 0.0259844
WASL Wiskott-Aldrich syndrome-like 0.0259541
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0259427
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.0259153
OAZ1 ornithine decarboxylase antizyme 1 0.0258874
PPP1R15B protein phosphatase 1, regulatory subunit 15B 0.0256453
MYO1E myosin IE 0.0255453
TXNIP thioredoxin interacting protein 0.0255015
HDLBP high density lipoprotein binding protein 0.0253731
RDX radixin 0.0252827
SHANK2 SH3 and multiple ankyrin repeat domains 2 0.0251997
STK4 serine/threonine kinase 4 0.0250743
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0250681
ABR active BCR-related 0.0250061
KTN1 kinectin 1 (kinesin receptor) 0.0245113
TCF25 transcription factor 25 (basic helix-loop-helix) 0.0245095
KRT81 keratin 81, type II 0.0244371
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.0244003
NEBL nebulette 0.0242989
ENAH enabled homolog (Drosophila) 0.0242857
INO80D INO80 complex subunit D 0.024246
LPP LIM domain containing preferred translocation partner in lipoma 0.0242357
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.024134
UBE2H ubiquitin-conjugating enzyme E2H 0.0241058
SMG6 SMG6 nonsense mediated mRNA decay factor 0.0240473
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.0240008
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 0.0239535
TMTC3 transmembrane and tetratricopeptide repeat containing 3 0.0238724
KDM5B lysine (K)-specific demethylase 5B 0.0238201
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0237583
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.0237543
SYT12 synaptotagmin XII 0.0236435
MAPK8 mitogen-activated protein kinase 8 0.0236102
PHACTR2 phosphatase and actin regulator 2 0.0235771
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.0235696
CANX calnexin 0.0235248
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.0235214
STC1 stanniocalcin 1 0.023288
RBM6 RNA binding motif protein 6 0.0232819
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.023231
FGF13 fibroblast growth factor 13 0.0231846
MED12 mediator complex subunit 12 0.0229309
MLXIP MLX interacting protein 0.0228972
ZNF791 zinc finger protein 791 0.0228922
RAB14 RAB14, member RAS oncogene family 0.0227901
SCRN1 secernin 1 0.0226506
GNA14 guanine nucleotide binding protein (G protein), alpha 14 0.0226414
TGOLN2 trans-golgi network protein 2 0.0226106
CD24 CD24 molecule 0.0224786
HLA-E major histocompatibility complex, class I, E 0.0223524
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.0222866
STX16 syntaxin 16 0.0222066
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.0221296
FAM217B family with sequence similarity 217, member B 0.022085
CCSER2 coiled-coil serine-rich protein 2 0.0220634
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 0.0220112
ARF1 ADP-ribosylation factor 1 0.022002
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.0219307
KIF5B kinesin family member 5B 0.0219042
AURKA aurora kinase A 0.0217428
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 0.0217316
FMN1 formin 1 0.0217251
MACC1 metastasis associated in colon cancer 1 0.0216338
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.02159
AREG amphiregulin 0.0215326
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 0.0214772
HP1BP3 heterochromatin protein 1, binding protein 3 0.0214347
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.021425
CCDC6 coiled-coil domain containing 6 0.021306
RPS27 ribosomal protein S27 0.0211613
TMOD3 tropomodulin 3 (ubiquitous) 0.0210532
NCKAP5 NCK-associated protein 5 0.0210045
MTPN myotrophin 0.0209931
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 0.0209522
CSNK2A2 casein kinase 2, alpha prime polypeptide 0.020837
GOLGA2 golgin A2 0.020781
REST RE1-silencing transcription factor 0.0207722
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.0207647
ATP5F1E ATP synthase F1 subunit epsilon 0.0207297
CALU calumenin 0.0206798
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 0.0205601
MAST4 microtubule associated serine/threonine kinase family member 4 0.0204916
HMGXB4 HMG box domain containing 4 0.0202607
PSME4 proteasome (prosome, macropain) activator subunit 4 0.020211
DCLK1 doublecortin-like kinase 1 0.0201774
BRD4 bromodomain containing 4 0.0201629
ZNF91 zinc finger protein 91 0.0201206
PDIA6 protein disulfide isomerase family A, member 6 0.0200635
COP1 COP1 E3 ubiquitin ligase 0.0199771
SUMO2 small ubiquitin-like modifier 2 0.0199612
SRFBP1 serum response factor binding protein 1 0.0198806
RPSA ribosomal protein SA 0.0198639
RPS18 ribosomal protein S18 0.0198444
TOM1L2 target of myb1-like 2 (chicken) 0.0198123
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.0197842
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 0.0197492
LDOC1 leucine zipper, down-regulated in cancer 1 0.0197446
CARM1 coactivator-associated arginine methyltransferase 1 0.019699
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.019683
SMIM44 small integral membrane protein 44 0.0195062
SERBP1 SERPINE1 mRNA binding protein 1 0.0194479
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.0194239
METTL16 methyltransferase like 16 0.0194027
ELP4 elongator acetyltransferase complex subunit 4 0.0193849
RABGAP1L RAB GTPase activating protein 1-like 0.0193295
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0193203
GOLGB1 golgin B1 0.0192799
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.019265
CXXC5 CXXC finger protein 5 0.0191938
PRDX1 peroxiredoxin 1 0.0191902
SRRM2 serine/arginine repetitive matrix 2 0.0191391
IREB2 iron-responsive element binding protein 2 0.0191187
CAPN8 calpain 8 0.0190529
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0190492
RPS20 ribosomal protein S20 0.0190222
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.0190137
JAK1 Janus kinase 1 0.0189974
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 0.0189886
GOLGA4 golgin A4 0.0189621
ADAM10 ADAM metallopeptidase domain 10 0.0189547
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.0189516
ZMYM2 zinc finger, MYM-type 2 0.018949
OSBPL8 oxysterol binding protein-like 8 0.018946
S100A11 S100 calcium binding protein A11 0.0189113
KHSRP KH-type splicing regulatory protein 0.0189068
RAD21 RAD21 homolog (S. pombe) 0.0188457
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.0188414
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.0188368
RPS17 ribosomal protein S17 0.0188366
RAD23B RAD23 homolog B (S. cerevisiae) 0.0188105
IRF2BPL interferon regulatory factor 2 binding protein-like 0.0187992
AKAP11 A kinase (PRKA) anchor protein 11 0.0187948
TMSB10 thymosin beta 10 0.018786
TIAM1 T-cell lymphoma invasion and metastasis 1 0.0187483
VGLL4 vestigial-like family member 4 0.018699
CNPY2 canopy FGF signaling regulator 2 0.0186916
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.0186632
CEP128 centrosomal protein 128kDa 0.0186552
MSRB1 methionine sulfoxide reductase B1 0.0186239
RPL4 ribosomal protein L4 0.0186163
ZNF106 zinc finger protein 106 0.0185786
RPL23 ribosomal protein L23 0.018578
COL4A5 collagen, type IV, alpha 5 0.0185451
SEC23IP SEC23 interacting protein 0.0185387
MARCKSL1 MARCKS-like 1 0.0184936
C14ORF132 chromosome 14 open reading frame 132 0.0184595
RC3H1 ring finger and CCCH-type domains 1 0.0184458
CEP290 centrosomal protein 290kDa 0.018433
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.0184152
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 0.0183388
GOLGA3 golgin A3 0.0182717
PHPT1 phosphohistidine phosphatase 1 0.0182179
TRIP4 thyroid hormone receptor interactor 4 0.0182023
EEF1B2 eukaryotic translation elongation factor 1 beta 2 0.0181977
DOCK5 dedicator of cytokinesis 5 0.0181644
ACTN1 actinin, alpha 1 0.01812
ZHX1 zinc fingers and homeoboxes 1 0.0180474
NME3 NME/NM23 nucleoside diphosphate kinase 3 0.0180171
ZFAND6 zinc finger, AN1-type domain 6 0.0179812
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.0179518
CDK4 cyclin-dependent kinase 4 0.0178567
KAT7 K(lysine) acetyltransferase 7 0.0178045
TPI1 triosephosphate isomerase 1 0.0177302
PARK7 parkinson protein 7 0.0176911
FAM120A family with sequence similarity 120A 0.0176909
PARP1 poly (ADP-ribose) polymerase 1 0.0176759
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.0176283
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.0176064
SET SET nuclear proto-oncogene 0.0175738
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 0.0175631
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0175419
AHCYL2 adenosylhomocysteinase-like 2 0.0175363
HEATR6 HEAT repeat containing 6 0.0175273
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.017457
NEMF nuclear export mediator factor 0.017447
MCM4 minichromosome maintenance complex component 4 0.0173969
RPL37A ribosomal protein L37a 0.017388
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.0173731
UXS1 UDP-glucuronate decarboxylase 1 0.0173668
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 0.0173596
RPL8 ribosomal protein L8 0.017354
PLA2G12A phospholipase A2, group XIIA 0.0172475
VAMP8 vesicle-associated membrane protein 8 0.0172026
ATP5MF ATP synthase membrane subunit f 0.0171903
ARHGAP12 Rho GTPase activating protein 12 0.0171826
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.017155
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0171159
TMEM64 transmembrane protein 64 0.0171097
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 0.0171031
RPS4X ribosomal protein S4, X-linked 0.0170994
SPAG9 sperm associated antigen 9 0.0170976
WAC WW domain containing adaptor with coiled-coil 0.0170676
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.0170525
TXNRD1 thioredoxin reductase 1 0.0170277
VEZF1 vascular endothelial zinc finger 1 0.0169959
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0169948
WIPF1 WAS/WASL interacting protein family, member 1 0.0169945
PBRM1 polybromo 1 0.0169769
MAVS mitochondrial antiviral signaling protein 0.0169541
CLU clusterin 0.0169344
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 0.0169331
TUG1 taurine up-regulated 1 (non-protein coding) 0.0169326
RPL35A ribosomal protein L35a 0.0169043
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 0.01685
VEZT vezatin, adherens junctions transmembrane protein 0.0167585
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.0167316
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 0.0167258
WWP1 WW domain containing E3 ubiquitin protein ligase 1 0.0166779
DCAF7 DDB1 and CUL4 associated factor 7 0.0166738
ZNF562 zinc finger protein 562 0.0166636
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0166555
TCEAL4 transcription elongation factor A (SII)-like 4 0.0165827
NCAPG2 non-SMC condensin II complex, subunit G2 0.0165545
HYOU1 hypoxia up-regulated 1 0.0165286
RHOD ras homolog family member D 0.0165177
TUFM Tu translation elongation factor, mitochondrial 0.0164426
UBE3C ubiquitin protein ligase E3C 0.0164156
RAP2C RAP2C, member of RAS oncogene family 0.0164068
GABPB1 GA binding protein transcription factor, beta subunit 1 0.0164048
FOXN3 forkhead box N3 0.0164011
LDHA lactate dehydrogenase A 0.016388
DCAF6 DDB1 and CUL4 associated factor 6 0.0163769
RPL19 ribosomal protein L19 0.0163744
NSMCE1 non-SMC element 1 homolog (S. cerevisiae) 0.0163727
NSD1 nuclear receptor binding SET domain protein 1 0.0163556
CRABP2 cellular retinoic acid binding protein 2 0.0163457
HELZ helicase with zinc finger 0.0163327
H2BC8 H2B clustered histone 8 0.0163191
CNIH4 cornichon family AMPA receptor auxiliary protein 4 0.016315
TBC1D2 TBC1 domain family, member 2 0.0162759
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.0162753
ZNF407 zinc finger protein 407 0.0162559
UBA6 ubiquitin-like modifier activating enzyme 6 0.0162444
NMT1 N-myristoyltransferase 1 0.0162217
BRD3 bromodomain containing 3 0.0162087
RAB2A RAB2A, member RAS oncogene family 0.016202
COX5B cytochrome c oxidase subunit Vb 0.0162003
ZCCHC8 zinc finger, CCHC domain containing 8 0.0161787
RARS2 arginyl-tRNA synthetase 2, mitochondrial 0.0161563
TRIM28 tripartite motif containing 28 0.0161494
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) 0.0161375
EPN2 epsin 2 0.0161211
MCM7 minichromosome maintenance complex component 7 0.0160709
RPLP2 ribosomal protein, large, P2 0.0160638
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.0160331
TBL1X transducin (beta)-like 1X-linked 0.0160133
FGD4 FYVE, RhoGEF and PH domain containing 4 0.0160066
KLHDC10 kelch domain containing 10 0.0159902
C5ORF24 chromosome 5 open reading frame 24 0.0159857
TBX2 T-box 2 0.0159376
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0158603
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0158519
MTDH metadherin 0.0158307
ATXN7 ataxin 7 0.0158125
PHACTR4 phosphatase and actin regulator 4 0.0158047
QSOX1 quiescin Q6 sulfhydryl oxidase 1 0.0157975
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0157613
NOP14 NOP14 nucleolar protein 0.0157272
SSH1 slingshot protein phosphatase 1 0.0157254
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 0.0157227
UGCG UDP-glucose ceramide glucosyltransferase 0.0156673
ANAPC11 anaphase promoting complex subunit 11 0.0155842
SHROOM2 shroom family member 2 0.0155838
BBX bobby sox homolog (Drosophila) 0.0155599
RPS24 ribosomal protein S24 0.0155591
PRELID3B PRELI domain containing 3B 0.0155504
SKIC3 SKI3 subunit of superkiller complex 0.015537
GMDS GDP-mannose 4,6-dehydratase 0.0154993
RPL31 ribosomal protein L31 0.0154857
GK5 glycerol kinase 5 (putative) 0.0154807
PRIM2 primase, DNA, polypeptide 2 (58kDa) 0.0154787
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 0.0154381
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.0154352
PURA purine-rich element binding protein A 0.0154323
PHF14 PHD finger protein 14 0.0154281
TCERG1 transcription elongation regulator 1 0.0154112
CDPF1 cysteine-rich, DPF motif domain containing 1 0.0153691
DCAF5 DDB1 and CUL4 associated factor 5 0.0153616
SAMD12 sterile alpha motif domain containing 12 0.0153367
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 0.0153263
ZNHIT1 zinc finger, HIT-type containing 1 0.0153015
LAMP2 lysosomal-associated membrane protein 2 0.015282
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.0152736
ZNF277 zinc finger protein 277 0.0152689
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 0.0152643
ABHD11 abhydrolase domain containing 11 0.01525
CCNE2 cyclin E2 0.0152154
ANXA2 annexin A2 0.0152134
MYDGF myeloid-derived growth factor 0.0152103
IFI27 interferon, alpha-inducible protein 27 0.0152082
PCNT pericentrin 0.0151434
UFL1 UFM1-specific ligase 1 0.0151314
ELOB elongin B 0.0151199
UBXN4 UBX domain protein 4 0.0151013
ATF5 activating transcription factor 5 0.0150974
SETX senataxin 0.0150432
ULK1 unc-51 like autophagy activating kinase 1 0.0150141
ECI1 enoyl-CoA delta isomerase 1 0.0149899
TTPAL tocopherol (alpha) transfer protein-like 0.0149812
RPL7L1 ribosomal protein L7-like 1 0.0149726
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 0.0149676
ARFGEF3 ARFGEF family member 3 0.0149668
FHIT fragile histidine triad 0.0149315
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) 0.0148974
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.0148496
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.0148175
RPL36AL ribosomal protein L36a-like 0.0148122
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C 0.0147973
NOL10 nucleolar protein 10 0.0147846
ACADVL acyl-CoA dehydrogenase, very long chain 0.0147691
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.0147413
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.0147361
TMEM263 transmembrane protein 263 0.0147057
HOMER2 homer scaffolding protein 2 0.0146388
SCAMP2 secretory carrier membrane protein 2 0.0145757
NUP210L nucleoporin 210kDa-like 0.0145724
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.0145646
PHF3 PHD finger protein 3 0.0145567
SRSF11 serine/arginine-rich splicing factor 11 0.0145013
RBM12 RNA binding motif protein 12 0.0144952
ZMAT2 zinc finger, matrin-type 2 0.0144905
ADISSP adipose secreted signaling protein 0.0144623
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.0144612
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 0.0144365
ZHX3 zinc fingers and homeoboxes 3 0.0144322
DAND5 DAN domain family member 5, BMP antagonist 0.0144177
MRPS18B mitochondrial ribosomal protein S18B 0.0144175
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.014399
NT5DC2 5'-nucleotidase domain containing 2 0.0143883
SFSWAP splicing factor, suppressor of white-apricot family 0.0143761
CHD1 chromodomain helicase DNA binding protein 1 0.0143689
CEP170 centrosomal protein 170kDa 0.0143567
C6ORF62 chromosome 6 open reading frame 62 0.014312
RUNDC1 RUN domain containing 1 0.0143031
SGPP1 sphingosine-1-phosphate phosphatase 1 0.014273
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 0.0142646
PRKCSH protein kinase C substrate 80K-H 0.0142552
TIMELESS timeless circadian clock 0.0142191
USP42 ubiquitin specific peptidase 42 0.0142179
TACC2 transforming, acidic coiled-coil containing protein 2 0.0142163
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.0142075
RPL34 ribosomal protein L34 0.014196
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.0141769
EEIG2 EEIG family member 2 0.0141766
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 0.014171
ZNF451 zinc finger protein 451 0.0141589
MARVELD2 MARVEL domain containing 2 0.0141403
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.0141088
UBE2B ubiquitin-conjugating enzyme E2B 0.0140741
HDGFL3 HDGF like 3 0.0140731
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.0140699
GMPS guanine monphosphate synthase 0.0140442
HSCB HscB mitochondrial iron-sulfur cluster co-chaperone 0.0139918
WASF2 WAS protein family, member 2 0.0139893
TNRC6A trinucleotide repeat containing 6A 0.0139808
USP8 ubiquitin specific peptidase 8 0.0139681
CHD3 chromodomain helicase DNA binding protein 3 0.0139585
EHBP1 EH domain binding protein 1 0.0139552
CLIP1 CAP-GLY domain containing linker protein 1 0.0139477
CTSB cathepsin B 0.0139392
GDI2 GDP dissociation inhibitor 2 0.0139274
NELFCD negative elongation factor complex member C/D 0.0139033
WNK1 WNK lysine deficient protein kinase 1 0.0138773
MGLL monoglyceride lipase 0.013869
SKI SKI proto-oncogene 0.0138495
SPAST spastin 0.0138397
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.0138338
KIDINS220 kinase D-interacting substrate, 220kDa 0.0138284
RANBP2 RAN binding protein 2 0.0138248
CSRP1 cysteine and glycine-rich protein 1 0.0138204
DKC1 dyskeratosis congenita 1, dyskerin 0.0138081
ACSS3 acyl-CoA synthetase short-chain family member 3 0.0138066
FOXO1 forkhead box O1 0.0137765
TRIM27 tripartite motif containing 27 0.0137591
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.0137562
YBX3 Y box binding protein 3 0.013754
PHB1 prohibitin 1 0.0137338

decreased expression

Symbol Name Standardized Value
GFRA1 GDNF family receptor alpha 1 -0.132117
IFI6 interferon, alpha-inducible protein 6 -0.119463
WWOX WW domain containing oxidoreductase -0.116833
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 -0.109585
BCAS3 breast carcinoma amplified sequence 3 -0.0958672
LRP1B low density lipoprotein receptor-related protein 1B -0.0929332
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -0.0851978
IGFBP5 insulin-like growth factor binding protein 5 -0.0837162
NCOA3 nuclear receptor coactivator 3 -0.0836648
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0815157
KRT8 keratin 8, type II -0.0727393
AGR2 anterior gradient 2 -0.0679289
GPC6 glypican 6 -0.0617088
RGS6 regulator of G-protein signaling 6 -0.0590844
TUBD1 tubulin, delta 1 -0.0575752
SIPA1L1 signal-induced proliferation-associated 1 like 1 -0.0552963
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -0.0534768
ESR1 estrogen receptor 1 -0.0529741
SULF2 sulfatase 2 -0.0514269
EMP2 epithelial membrane protein 2 -0.0512839
PRKCE protein kinase C, epsilon -0.0508901
TMCC1 transmembrane and coiled-coil domain family 1 -0.0508194
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 -0.0481629
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0474046
UNK unkempt family zinc finger -0.047013
SRPK2 SRSF protein kinase 2 -0.0457925
ERBB4 erb-b2 receptor tyrosine kinase 4 -0.0441177
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 -0.0440694
NCAM2 neural cell adhesion molecule 2 -0.0439733
NPAS3 neuronal PAS domain protein 3 -0.043749
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -0.0423053
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -0.0419168
GRHL2 grainyhead-like 2 (Drosophila) -0.0412874
CNKSR3 CNKSR family member 3 -0.0409713
VMP1 vacuole membrane protein 1 -0.040942
BAZ1A bromodomain adjacent to zinc finger domain, 1A -0.0405608
R3HDM2 R3H domain containing 2 -0.0401675
XPO1 exportin 1 -0.0398945
PARD3 par-3 family cell polarity regulator -0.0398641
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.0395666
RPS29 ribosomal protein S29 -0.0388924
IQGAP1 IQ motif containing GTPase activating protein 1 -0.0380851
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.03738
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 -0.0372729
TNRC18 trinucleotide repeat containing 18 -0.0370379
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0363212
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.0360933
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0355277
SIDT1 SID1 transmembrane family, member 1 -0.0353342
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.035126
GLG1 golgi glycoprotein 1 -0.0343248
PPP1R12B protein phosphatase 1, regulatory subunit 12B -0.0336592
PUM1 pumilio RNA-binding family member 1 -0.033157
JARID2 jumonji, AT rich interactive domain 2 -0.0324829
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 -0.0324324
PLEC plectin -0.0316206
NR6A1 nuclear receptor subfamily 6, group A, member 1 -0.031543
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.0312687
CD81 CD81 molecule -0.0311208
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha -0.0309981
ACTN4 actinin, alpha 4 -0.0308979
ZNF638 zinc finger protein 638 -0.0308502
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0307752
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.0306438
LDLR low density lipoprotein receptor -0.0303208
ANKRD11 ankyrin repeat domain 11 -0.0303194
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) -0.0302954
PPP4R3A protein phosphatase 4 regulatory subunit 3A -0.0300105
HMCN1 hemicentin 1 -0.0299541
RAD51B RAD51 paralog B -0.0299135
CDK13 cyclin-dependent kinase 13 -0.0297311
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.0293365
DHCR7 7-dehydrocholesterol reductase -0.0291388
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 -0.028957
CLASP1 cytoplasmic linker associated protein 1 -0.0289533
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.0288522
ITPRID2 ITPR interacting domain containing 2 -0.0288286
PTPRF protein tyrosine phosphatase, receptor type, F -0.0287868
SDK1 sidekick cell adhesion molecule 1 -0.0287481
RHPN2 rhophilin, Rho GTPase binding protein 2 -0.0284844
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0284745
TENM3 teneurin transmembrane protein 3 -0.0282464
BIRC6 baculoviral IAP repeat containing 6 -0.0281374
RPL37 ribosomal protein L37 -0.0281282
CHD9 chromodomain helicase DNA binding protein 9 -0.0278167
DLG1 discs, large homolog 1 (Drosophila) -0.0277653
HIPK1 homeodomain interacting protein kinase 1 -0.0274485
WBP1L WW domain binding protein 1-like -0.0273911
STK24 serine/threonine kinase 24 -0.02738
PPP6R3 protein phosphatase 6, regulatory subunit 3 -0.0273192
DLG5 discs, large homolog 5 (Drosophila) -0.0272988
SPG11 spastic paraplegia 11 (autosomal recessive) -0.0269507
TRPS1 trichorhinophalangeal syndrome I -0.0268822
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.0268563
SND1 staphylococcal nuclease and tudor domain containing 1 -0.026706
TFF1 trefoil factor 1 -0.0266173
NCOA2 nuclear receptor coactivator 2 -0.0265086
RPL28 ribosomal protein L28 -0.0264747
H1-10 H1.10 linker histone -0.026066
TMPRSS4 transmembrane protease, serine 4 -0.0259057
TPM4 tropomyosin 4 -0.0258746
CUX1 cut-like homeobox 1 -0.0258052
RHOBTB3 Rho-related BTB domain containing 3 -0.0257158
CLTC clathrin, heavy chain (Hc) -0.025706
PALLD palladin, cytoskeletal associated protein -0.0256381
DOCK1 dedicator of cytokinesis 1 -0.0255158
LY6E lymphocyte antigen 6 complex, locus E -0.0254288
ATXN7L1 ataxin 7-like 1 -0.0254006
FRMD5 FERM domain containing 5 -0.0253911
RTF2 replication termination factor 2 -0.0253634
FAF1 Fas (TNFRSF6) associated factor 1 -0.0250587
PDS5A PDS5 cohesin associated factor A -0.024815
ADCY1 adenylate cyclase 1 (brain) -0.0246795
GPATCH8 G patch domain containing 8 -0.0245685
BSG basigin (Ok blood group) -0.0245596
WWC1 WW and C2 domain containing 1 -0.0244425
C2CD5 C2 calcium-dependent domain containing 5 -0.0244217
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -0.0241713
EAPP E2F-associated phosphoprotein -0.0240961
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 -0.0238957
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -0.0238068
IGF1R insulin-like growth factor 1 receptor -0.0236106
LETMD1 LETM1 domain containing 1 -0.0236036
BMP7 bone morphogenetic protein 7 -0.0235815
MACF1 microtubule-actin crosslinking factor 1 -0.0235425
UTRN utrophin -0.0234385
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -0.0233135
SYT1 synaptotagmin I -0.0233031
CCDC170 coiled-coil domain containing 170 -0.0232788
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -0.0232668
MTSS1 metastasis suppressor 1 -0.0231628
FOXK1 forkhead box K1 -0.0231215
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -0.0230378
AKAP8L A kinase (PRKA) anchor protein 8-like -0.0229454
CALR calreticulin -0.0228978
RNASE3 ribonuclease, RNase A family, 3 -0.0228155
SFTPA2 surfactant protein A2 -0.0227659
SHISA9 shisa family member 9 -0.0226271
LMNA lamin A/C -0.0225542
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 -0.0225447
KYNU kynureninase -0.022499
IRS1 insulin receptor substrate 1 -0.0224608
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.0224497
RREB1 ras responsive element binding protein 1 -0.0224208
RAB28 RAB28, member RAS oncogene family -0.0221722
DTNB dystrobrevin, beta -0.0221685
TRA2A transformer 2 alpha homolog (Drosophila) -0.0219222
SYNGAP1 synaptic Ras GTPase activating protein 1 -0.0218438
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) -0.0217212
PDZRN3 PDZ domain containing ring finger 3 -0.021688
TPR translocated promoter region, nuclear basket protein -0.0215032
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A -0.021484
PHF21A PHD finger protein 21A -0.0212882
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -0.0212429
MECOM MDS1 and EVI1 complex locus -0.0212337
STYXL1 serine/threonine/tyrosine interacting-like 1 -0.0211207
SFXN2 sideroflexin 2 -0.0211111
FNDC3A fibronectin type III domain containing 3A -0.0208176
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -0.0207682
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -0.0206544
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 -0.0206539
MTCH2 mitochondrial carrier 2 -0.0206289
CNOT2 CCR4-NOT transcription complex, subunit 2 -0.0205206
EYA3 EYA transcriptional coactivator and phosphatase 3 -0.0205157
CCAR1 cell division cycle and apoptosis regulator 1 -0.0205153
ACYP2 acylphosphatase 2, muscle type -0.0203334
CD63 CD63 molecule -0.020316
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa -0.0202969
SENP6 SUMO1/sentrin specific peptidase 6 -0.020261
SETD1B SET domain containing 1B -0.0201701
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.0201321
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase -0.0201164
SYTL4 synaptotagmin-like 4 -0.0200676
MAP7 microtubule-associated protein 7 -0.0200214
TPD52 tumor protein D52 -0.0199237
KMT2C lysine (K)-specific methyltransferase 2C -0.0198959
RCOR1 REST corepressor 1 -0.0197816
MEIS2 Meis homeobox 2 -0.0197374
PBX3 pre-B-cell leukemia homeobox 3 -0.0197136
ZC3H18 zinc finger CCCH-type containing 18 -0.0197121
SSBP2 single-stranded DNA binding protein 2 -0.0196373
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.0195753
FOXP1 forkhead box P1 -0.0195364
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -0.0194941
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E -0.0192816
CAPRIN1 cell cycle associated protein 1 -0.0192204
PCLO piccolo presynaptic cytomatrix protein -0.0191873
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.0191815
KDM3B lysine (K)-specific demethylase 3B -0.0191171
EXOC6B exocyst complex component 6B -0.0190936
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0190307
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 -0.0190204
DST dystonin -0.018975
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -0.0188564
PLEKHA6 pleckstrin homology domain containing, family A member 6 -0.0188435
STARD10 StAR-related lipid transfer (START) domain containing 10 -0.018841
THRB thyroid hormone receptor, beta -0.0188305
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.0187409
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein -0.0186979
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -0.0186936
ZHX2 zinc fingers and homeoboxes 2 -0.018687
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) -0.0186695
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 -0.0186618
BCAS2 breast carcinoma amplified sequence 2 -0.0186258
SCAF8 SR-related CTD-associated factor 8 -0.018591
UBE2G1 ubiquitin-conjugating enzyme E2G 1 -0.0185213
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 -0.0184013
GIGYF2 GRB10 interacting GYF protein 2 -0.0183879
GPHN gephyrin -0.0183307
CLCN3 chloride channel, voltage-sensitive 3 -0.0182662
DNASE2 deoxyribonuclease II, lysosomal -0.0182424
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 -0.018242
FANCA Fanconi anemia, complementation group A -0.0182047
HIP1 huntingtin interacting protein 1 -0.0181713
ZDHHC12 zinc finger, DHHC-type containing 12 -0.018151
UBR2 ubiquitin protein ligase E3 component n-recognin 2 -0.0181277
NCOA6 nuclear receptor coactivator 6 -0.0181084
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase -0.0180967
GINS1 GINS complex subunit 1 (Psf1 homolog) -0.0180856
DPY19L4 dpy-19-like 4 (C. elegans) -0.0180638
CHD6 chromodomain helicase DNA binding protein 6 -0.017916
LAPTM4A lysosomal protein transmembrane 4 alpha -0.0178805
ARHGAP44 Rho GTPase activating protein 44 -0.0178757
MRPS11 mitochondrial ribosomal protein S11 -0.0178695
SGMS1 sphingomyelin synthase 1 -0.0178467
GSPT1 G1 to S phase transition 1 -0.0177847
MAML3 mastermind-like 3 (Drosophila) -0.0176855
GRN granulin -0.0176691
PGPEP1 pyroglutamyl-peptidase I -0.0175493
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase -0.0175257
TEX14 testis expressed 14 -0.0174997
ARMH3 armadillo like helical domain containing 3 -0.0174741
ARHGAP32 Rho GTPase activating protein 32 -0.0174725
SEC11A SEC11 homolog A (S. cerevisiae) -0.0174524
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0173998
JAK2 Janus kinase 2 -0.0173778
FAM13B family with sequence similarity 13, member B -0.0173619
EPCAM epithelial cell adhesion molecule -0.0173383
SKA2 spindle and kinetochore associated complex subunit 2 -0.0173019
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) -0.0172684
CTBP2 C-terminal binding protein 2 -0.017246
KHDC4 KH domain containing 4, pre-mRNA splicing factor -0.0172393
ARHGAP35 Rho GTPase activating protein 35 -0.0172254
NUMA1 nuclear mitotic apparatus protein 1 -0.0171795
ARMC9 armadillo repeat containing 9 -0.0171791
MGP matrix Gla protein -0.0171763
BMPR1A bone morphogenetic protein receptor, type IA -0.0171509
PERP PERP, TP53 apoptosis effector -0.0170318
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.0170163
TRAK1 trafficking protein, kinesin binding 1 -0.0170053
STX6 syntaxin 6 -0.0170039
KIAA1671 KIAA1671 -0.0169777
CHLSN cholesin -0.0169719
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.0169643
PTGES2 prostaglandin E synthase 2 -0.0169558
EMC3 ER membrane protein complex subunit 3 -0.0169216
MACROD2 MACRO domain containing 2 -0.0169139
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0169006
PRRC2B proline-rich coiled-coil 2B -0.0168858
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 -0.0168806
SAP130 Sin3A-associated protein, 130kDa -0.0168801
TSC22D1 TSC22 domain family, member 1 -0.0168716
GSK3B glycogen synthase kinase 3 beta -0.016821
KCNK1 potassium channel, two pore domain subfamily K, member 1 -0.0168193
ZC3H14 zinc finger CCCH-type containing 14 -0.0168096
FIGN fidgetin -0.0167873
SIKE1 suppressor of IKBKE 1 -0.0167599
CENPP centromere protein P -0.0167342
COBL cordon-bleu WH2 repeat protein -0.0167096
KLHL20 kelch-like family member 20 -0.0167092
FBXL18 F-box and leucine-rich repeat protein 18 -0.0166945
ADGRV1 adhesion G protein-coupled receptor V1 -0.016689
FUBP3 far upstream element (FUSE) binding protein 3 -0.016679
LRIF1 ligand dependent nuclear receptor interacting factor 1 -0.0166694
PRKCA protein kinase C, alpha -0.016595
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0165709
AIG1 androgen-induced 1 -0.0165661
TBC1D5 TBC1 domain family, member 5 -0.0165596
ATRAID all-trans retinoic acid-induced differentiation factor -0.016522
CLPTM1 cleft lip and palate associated transmembrane protein 1 -0.0165091
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0165058
HNRNPLL heterogeneous nuclear ribonucleoprotein L-like -0.0164833
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 -0.0164407
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide -0.016426
DEGS2 delta(4)-desaturase, sphingolipid 2 -0.0164061
XPO4 exportin 4 -0.0163791
SBF2 SET binding factor 2 -0.0163779
SHROOM3 shroom family member 3 -0.0163673
USP15 ubiquitin specific peptidase 15 -0.0163418
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.0163406
MCMBP minichromosome maintenance complex binding protein -0.0163298
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.0163048
GCN1 GCN1 activator of EIF2AK4 -0.0162837
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.0162264
TTC28 tetratricopeptide repeat domain 28 -0.016204
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -0.0161954
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0161246
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -0.0160878
FOCAD focadhesin -0.0160725
UBE4B ubiquitination factor E4B -0.0160659
CA4 carbonic anhydrase IV -0.0160531
CERCAM cerebral endothelial cell adhesion molecule -0.0160528
CYFIP1 cytoplasmic FMR1 interacting protein 1 -0.0160136
SNRPA small nuclear ribonucleoprotein polypeptide A -0.0160127
DHDDS dehydrodolichyl diphosphate synthase -0.015945
ARHGAP10 Rho GTPase activating protein 10 -0.0159303
NBEAL1 neurobeachin-like 1 -0.0159134
ZRANB3 zinc finger, RAN-binding domain containing 3 -0.0159045
ABHD17C abhydrolase domain containing 17C -0.015898
CDC73 cell division cycle 73 -0.0158822
ADCY9 adenylate cyclase 9 -0.0158816
RABGAP1 RAB GTPase activating protein 1 -0.0158767
SETDB1 SET domain, bifurcated 1 -0.015855
BZW2 basic leucine zipper and W2 domains 2 -0.0158506
SNX1 sorting nexin 1 -0.0157932
HACD2 3-hydroxyacyl-CoA dehydratase 2 -0.0157879
TRIM33 tripartite motif containing 33 -0.0157048
GABPB2 GA binding protein transcription factor, beta subunit 2 -0.015682
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -0.0156808
ZMYM5 zinc finger, MYM-type 5 -0.0156709
UGDH UDP-glucose 6-dehydrogenase -0.0156589
KDM6A lysine (K)-specific demethylase 6A -0.015654
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) -0.0156337
RPS11 ribosomal protein S11 -0.0156249
GPR137C G protein-coupled receptor 137C -0.0156073
CREM cAMP responsive element modulator -0.0155812
MYO15B myosin XVB -0.0155697
EXOSC1 exosome component 1 -0.0155223
RAB6A RAB6A, member RAS oncogene family -0.0155223
KCNK5 potassium channel, two pore domain subfamily K, member 5 -0.0154783
AMBRA1 autophagy/beclin-1 regulator 1 -0.0154117
CA8 carbonic anhydrase VIII -0.0153984
NSD3 nuclear receptor binding SET domain protein 3 -0.0153969
KAT6B K(lysine) acetyltransferase 6B -0.015395
UBE2D3 ubiquitin-conjugating enzyme E2D 3 -0.0153656
CSPP1 centrosome and spindle pole associated protein 1 -0.0153634
TASP1 taspase, threonine aspartase, 1 -0.015313
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1 -0.0152465
SAMTOR S-adenosylmethionine sensor upstream of mTORC1 -0.0152445
CADM1 cell adhesion molecule 1 -0.0152182
RAD9A RAD9 homolog A (S. pombe) -0.0152017
HAT1 histone acetyltransferase 1 -0.0151816
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.0151094
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 -0.0150923
AMZ1 archaelysin family metallopeptidase 1 -0.0150709
RBPMS RNA binding protein with multiple splicing -0.015068
LDLRAD4 low density lipoprotein receptor class A domain containing 4 -0.0150498
SOS1 son of sevenless homolog 1 (Drosophila) -0.0149539
MYB v-myb avian myeloblastosis viral oncogene homolog -0.0149466
CERT1 ceramide transporter 1 -0.0149435
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) -0.0148983
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -0.0148937
TLK2 tousled-like kinase 2 -0.0148847
SLC25A26 solute carrier family 25 (S-adenosylmethionine carrier), member 26 -0.0148507
DIAPH1 diaphanous-related formin 1 -0.0148351
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D -0.0147976
LUC7L LUC7-like (S. cerevisiae) -0.014792
LRP10 low density lipoprotein receptor-related protein 10 -0.0147912
EXT1 exostosin glycosyltransferase 1 -0.0147794
INTS2 integrator complex subunit 2 -0.0147669
PTRH2 peptidyl-tRNA hydrolase 2 -0.0147351
MBTD1 mbt domain containing 1 -0.0147116
SLC38A10 solute carrier family 38, member 10 -0.0146843
ESYT1 extended synaptotagmin-like protein 1 -0.0146638
PDS5B PDS5 cohesin associated factor B -0.0146355
SLC35F5 solute carrier family 35, member F5 -0.0146235
SPATS2 spermatogenesis associated, serine-rich 2 -0.0146187
FBXO42 F-box protein 42 -0.0145989
DRAM1 DNA-damage regulated autophagy modulator 1 -0.0145653
HID1 HID1 domain containing -0.0145363
STAU1 staufen double-stranded RNA binding protein 1 -0.0144935
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0144922
FN1 fibronectin 1 -0.0144898
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -0.0144622
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -0.0144332
ZNF609 zinc finger protein 609 -0.014396
IFT88 intraflagellar transport 88 -0.0143913
ARID1B AT rich interactive domain 1B (SWI1-like) -0.0143276
ANXA11 annexin A11 -0.0143185
THOC2 THO complex 2 -0.0142474
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 -0.0142445
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 -0.014236
RNF168 ring finger protein 168, E3 ubiquitin protein ligase -0.014234
NUDC nudC nuclear distribution protein -0.0142087
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 -0.0142028
TAC4 tachykinin 4 (hemokinin) -0.0141656
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 -0.0141637
ALMS1 Alstrom syndrome protein 1 -0.0141621
TBCD tubulin folding cofactor D -0.0141602
GSE1 Gse1 coiled-coil protein -0.0141506
FAF2 Fas associated factor family member 2 -0.0141499
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -0.0141249
RHOA ras homolog family member A -0.014121
RPS25 ribosomal protein S25 -0.0140935
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -0.0140856
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit -0.0140173
ARHGAP24 Rho GTPase activating protein 24 -0.013998
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) -0.0139735
PDE7A phosphodiesterase 7A -0.0138993
POC1B POC1 centriolar protein B -0.013896
LIN54 lin-54 DREAM MuvB core complex component -0.0138779
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -0.0138672
ATOSA atos homolog A -0.0138651
SCARB1 scavenger receptor class B, member 1 -0.0138311
MCM3AP minichromosome maintenance complex component 3 associated protein -0.0138215
WDR20 WD repeat domain 20 -0.0137671
RNF139 ring finger protein 139 -0.0137492
ZSWIM5 zinc finger, SWIM-type containing 5 -0.0137377
EFL1 elongation factor like GTPase 1 -0.0137309
FOXJ3 forkhead box J3 -0.0137279
CA12 carbonic anhydrase XII -0.0137053
TOP6BL TOP6B like initiator of meiotic double strand breaks -0.0136814
STAMBP STAM binding protein -0.0136663
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) -0.0136344
ANO6 anoctamin 6 -0.013633
GTF2IRD1 GTF2I repeat domain containing 1 -0.0135797
STRN striatin, calmodulin binding protein -0.013574
UBE3A ubiquitin protein ligase E3A -0.0135631
NPDC1 neural proliferation, differentiation and control, 1 -0.0135564
SPATS2L spermatogenesis associated, serine-rich 2-like -0.0135503
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) -0.0135113
SIK2 salt-inducible kinase 2 -0.0135075
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0135023
PAN3 PAN3 poly(A) specific ribonuclease subunit -0.0134703
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.0134675
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.0134623
PACS1 phosphofurin acidic cluster sorting protein 1 -0.0134522
TARBP1 TAR (HIV-1) RNA binding protein 1 -0.0134399
DCAF1 DDB1 and CUL4 associated factor 1 -0.01342
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase -0.0134093
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 -0.0133869
RMI1 RecQ mediated genome instability 1 -0.0133847
PRPF40B PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) -0.0133821
H2AC6 H2A clustered histone 6 -0.0133802
VCL vinculin -0.0133662
PICALM phosphatidylinositol binding clathrin assembly protein -0.0133462
USPL1 ubiquitin specific peptidase like 1 -0.0133239
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.01332
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 -0.0133017
LARP4B La ribonucleoprotein domain family, member 4B -0.0132761
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 -0.0132697
WHRN whirlin -0.0132563
ATP5MC1 ATP synthase membrane subunit c locus 1 -0.0132453
FRYL FRY-like -0.0132086
AEBP2 AE binding protein 2 -0.0131607
SLC75A1 solute carrier family 75 member 1 -0.0131576
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.0131565
BLTP2 bridge-like lipid transfer protein family member 2 -0.0131324
PIGT phosphatidylinositol glycan anchor biosynthesis, class T -0.0131171
CDK5RAP2 CDK5 regulatory subunit associated protein 2 -0.0131135
ICA1 islet cell autoantigen 1, 69kDa -0.0131067
CAMK2G calcium/calmodulin-dependent protein kinase II gamma -0.0130831
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit -0.0130719
PLEKHA8 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 -0.013065
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 -0.0130194
RBM23 RNA binding motif protein 23 -0.0130062
ZBTB35 zinc finger and BTB domain containing 35 -0.0129658
CTNNA3 catenin (cadherin-associated protein), alpha 3 -0.0129575
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 -0.0129556
ARCN1 archain 1 -0.0129476
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) -0.0129355
CENPN centromere protein N -0.0129045
NHSL1 NHS-like 1 -0.0129027
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -0.0128843
ARID3A AT rich interactive domain 3A (BRIGHT-like) -0.0128743
KIAA2026 KIAA2026 -0.0128725
SLTM SAFB-like, transcription modulator -0.0128642
CATSPERG catsper channel auxiliary subunit gamma -0.0128569
ATG4B autophagy related 4B, cysteine peptidase -0.0128119
PDK3 pyruvate dehydrogenase kinase, isozyme 3 -0.0128024
AHI1 Abelson helper integration site 1 -0.0128012
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.0127953
MAN2C1 mannosidase, alpha, class 2C, member 1 -0.0127848
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0127775
RNF130 ring finger protein 130 -0.0127759
ABI2 abl-interactor 2 -0.012766
SDC4 syndecan 4 -0.0127542
GDE1 glycerophosphodiester phosphodiesterase 1 -0.0127516
SEM1 SEM1 26S proteasome subunit -0.0127323
PPP2R2D protein phosphatase 2, regulatory subunit B, delta -0.0127008
PSME3IP1 proteasome activator subunit 3 interacting protein 1 -0.0126564
KIAA1217 KIAA1217 -0.0126253
HNRNPM heterogeneous nuclear ribonucleoprotein M -0.0126163
LITAF lipopolysaccharide-induced TNF factor -0.0126003
RTTN rotatin -0.0125981
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.0125692
MRTFA myocardin related transcription factor A -0.0125574
MTOR mechanistic target of rapamycin (serine/threonine kinase) -0.0125478
PTPRG protein tyrosine phosphatase, receptor type, G -0.0125455
MARCHF6 membrane associated ring-CH-type finger 6 -0.0125231
UNKL unkempt family zinc finger-like -0.012506
MCM9 minichromosome maintenance complex component 9 -0.0125038
EDRF1 erythroid differentiation regulatory factor 1 -0.0124988
ATL3 atlastin GTPase 3 -0.0124932
GINM1 glycoprotein integral membrane 1 -0.0124679
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) -0.0124636
ZNF730 zinc finger protein 730 -0.0124612
FKBP3 FK506 binding protein 3, 25kDa -0.0124612
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.012426
MBD5 methyl-CpG binding domain protein 5 -0.0124064