MCF7_SGI-1776 free base_1µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description SGI-1776 free base 1µM perturbation in MCF7 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the MCF7_SGI-1776 free base_1µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
KRT8 keratin 8, type II 0.175845
MRPL13 mitochondrial ribosomal protein L13 0.111951
TPM4 tropomyosin 4 0.105946
RPL30 ribosomal protein L30 0.105891
RPS2 ribosomal protein S2 0.0914255
UGDH UDP-glucose 6-dehydrogenase 0.0864305
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.0833394
VMP1 vacuole membrane protein 1 0.0813357
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0812061
RPS3 ribosomal protein S3 0.0787915
SYTL2 synaptotagmin-like 2 0.0774969
RPS5 ribosomal protein S5 0.0715207
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0678544
CLIC4 chloride intracellular channel 4 0.0645521
RPS21 ribosomal protein S21 0.0639546
TRIM37 tripartite motif containing 37 0.0621515
RPLP0 ribosomal protein, large, P0 0.059302
LDLR low density lipoprotein receptor 0.0573992
RPL15 ribosomal protein L15 0.0561145
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.055922
RPS17 ribosomal protein S17 0.0546
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 0.0542986
RACK1 receptor for activated C kinase 1 0.0542414
PACS1 phosphofurin acidic cluster sorting protein 1 0.0541276
CALCR calcitonin receptor 0.0537168
CST3 cystatin C 0.0514801
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 0.0492793
CSDE1 cold shock domain containing E1, RNA-binding 0.0484907
RPL29 ribosomal protein L29 0.0453712
RPL7A ribosomal protein L7a 0.0451007
CLDN3 claudin 3 0.0440475
RPS29 ribosomal protein S29 0.0432554
MYH9 myosin, heavy chain 9, non-muscle 0.0430396
DHCR7 7-dehydrocholesterol reductase 0.0423423
MALRD1 MAM and LDL receptor class A domain containing 1 0.0423351
PARD6B par-6 family cell polarity regulator beta 0.0420584
TNRC18 trinucleotide repeat containing 18 0.0420397
H3-3B H3.3 histone B 0.0416467
FLNB filamin B, beta 0.0408333
LITAF lipopolysaccharide-induced TNF factor 0.0404609
UBL4A ubiquitin-like 4A 0.0404199
PAWR PRKC, apoptosis, WT1, regulator 0.0404188
PKM pyruvate kinase, muscle 0.0402141
FTL ferritin, light polypeptide 0.040199
GLCCI1 glucocorticoid induced 1 0.0399374
KMT2A lysine (K)-specific methyltransferase 2A 0.0398806
RPLP1 ribosomal protein, large, P1 0.0393018
DCDC2 doublecortin domain containing 2 0.0392537
CUX1 cut-like homeobox 1 0.0390766
BCAS3 breast carcinoma amplified sequence 3 0.0386964
FXYD3 FXYD domain containing ion transport regulator 3 0.0386107
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.0384432
FBXW11 F-box and WD repeat domain containing 11 0.0382899
CSNK1A1 casein kinase 1, alpha 1 0.0380222
CENPB centromere protein B, 80kDa 0.0379434
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0376986
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 0.037698
RPL23A ribosomal protein L23a 0.0375717
IGFBP5 insulin-like growth factor binding protein 5 0.0372502
IQGAP1 IQ motif containing GTPase activating protein 1 0.0371752
CEMIP2 cell migration inducing hyaluronidase 2 0.0361934
PDZRN3 PDZ domain containing ring finger 3 0.0357162
ADIPOR2 adiponectin receptor 2 0.0355649
PHC3 polyhomeotic homolog 3 (Drosophila) 0.0354973
S100A11 S100 calcium binding protein A11 0.0352286
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 0.034825
ALCAM activated leukocyte cell adhesion molecule 0.034801
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0347899
WASF2 WAS protein family, member 2 0.0345243
MLPH melanophilin 0.0345111
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.034254
SUCO SUN domain containing ossification factor 0.0342346
RPL32 ribosomal protein L32 0.0342146
STARD10 StAR-related lipid transfer (START) domain containing 10 0.0340248
ATP9A ATPase, class II, type 9A 0.0339651
BASP1 brain abundant, membrane attached signal protein 1 0.0339371
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 0.0337686
RPS8 ribosomal protein S8 0.0332383
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.0331899
PCED1B PC-esterase domain containing 1B 0.0331296
RPS19 ribosomal protein S19 0.0330723
ITCH itchy E3 ubiquitin protein ligase 0.0329246
RPS11 ribosomal protein S11 0.032022
RHOBTB3 Rho-related BTB domain containing 3 0.0316895
SPTBN1 spectrin, beta, non-erythrocytic 1 0.03158
RPS14 ribosomal protein S14 0.031532
RPL37A ribosomal protein L37a 0.0308148
SPTSSB serine palmitoyltransferase, small subunit B 0.0307442
CD9 CD9 molecule 0.030712
FOXJ3 forkhead box J3 0.0302359
GATA3 GATA binding protein 3 0.0302064
FLNA filamin A, alpha 0.0301261
JAK1 Janus kinase 1 0.0300267
RPL4 ribosomal protein L4 0.0299374
RIGI RNA sensor RIG-I 0.0293279
RPL19 ribosomal protein L19 0.0291377
BCAS1 breast carcinoma amplified sequence 1 0.0290832
CD59 CD59 molecule, complement regulatory protein 0.0281435
BICD1 bicaudal D homolog 1 (Drosophila) 0.0277804
RPL8 ribosomal protein L8 0.0276436
DPYD dihydropyrimidine dehydrogenase 0.0274352
PLD3 phospholipase D family, member 3 0.0274003
MAN1A1 mannosidase, alpha, class 1A, member 1 0.0273967
EEIG1 estrogen-induced osteoclastogenesis regulator 1 0.0273613
PKP4 plakophilin 4 0.0273201
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 0.0271625
CD47 CD47 molecule 0.0268835
NPAS3 neuronal PAS domain protein 3 0.0268778
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 0.0268523
MIDEAS mitotic deacetylase associated SANT domain protein 0.0266379
NCAM2 neural cell adhesion molecule 2 0.0265574
H2AC6 H2A clustered histone 6 0.0265528
RPS18 ribosomal protein S18 0.0264574
SGMS1 sphingomyelin synthase 1 0.0263051
CADM1 cell adhesion molecule 1 0.0261328
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.0259845
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.0259485
EEF2 eukaryotic translation elongation factor 2 0.0257098
CAPNS1 calpain, small subunit 1 0.0256798
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 0.0254016
LTBP1 latent transforming growth factor beta binding protein 1 0.0252925
NPC1 Niemann-Pick disease, type C1 0.0252885
DHRS7B dehydrogenase/reductase (SDR family) member 7B 0.0249482
PRSS23 protease, serine, 23 0.0247608
RPS15 ribosomal protein S15 0.0246526
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.0246207
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.0245826
ATOSA atos homolog A 0.0245478
COL5A1 collagen, type V, alpha 1 0.0244014
RPL28 ribosomal protein L28 0.024223
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.023993
TENM3 teneurin transmembrane protein 3 0.0239819
GRAMD1A GRAM domain containing 1A 0.0239407
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.0238966
TTC3 tetratricopeptide repeat domain 3 0.0238891
RPS16 ribosomal protein S16 0.0237821
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.0237013
RDX radixin 0.0236904
CCND3 cyclin D3 0.0235438
SMIM14 small integral membrane protein 14 0.0234396
MED13 mediator complex subunit 13 0.0233988
APP amyloid beta (A4) precursor protein 0.0233716
NQO1 NAD(P)H dehydrogenase, quinone 1 0.023348
CFAP161 cilia and flagella associated protein 161 0.023343
AUTS2 autism susceptibility candidate 2 0.0232961
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0232711
RPL3 ribosomal protein L3 0.0231628
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0229937
EPHA7 EPH receptor A7 0.0229305
FGD4 FYVE, RhoGEF and PH domain containing 4 0.0228787
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.0226359
GATAD2A GATA zinc finger domain containing 2A 0.0225664
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 0.0225459
RHPN2 rhophilin, Rho GTPase binding protein 2 0.0224787
RAB6A RAB6A, member RAS oncogene family 0.0224584
ARSD arylsulfatase D 0.0222807
ZNF33A zinc finger protein 33A 0.02215
PTPRK protein tyrosine phosphatase, receptor type, K 0.0221387
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.0220808
RAB3D RAB3D, member RAS oncogene family 0.0220097
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.0219124
ZFP36L2 ZFP36 ring finger protein-like 2 0.0217864
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.0217585
ZDHHC9 zinc finger, DHHC-type containing 9 0.0217238
TSC22D1 TSC22 domain family, member 1 0.0215981
PDZD8 PDZ domain containing 8 0.0215609
KMT5B lysine methyltransferase 5B 0.0214048
FTH1 ferritin, heavy polypeptide 1 0.0213168
RIPOR3 RIPOR family member 3 0.021315
UBE2R2 ubiquitin-conjugating enzyme E2R 2 0.0211562
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0210868
SH3GLB2 SH3-domain GRB2-like endophilin B2 0.021071
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.0209425
ETF1 eukaryotic translation termination factor 1 0.0208877
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 0.0207786
CD24 CD24 molecule 0.0207243
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 0.0206985
DSPP dentin sialophosphoprotein 0.0205835
PERP PERP, TP53 apoptosis effector 0.0205086
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0204881
COG5 component of oligomeric golgi complex 5 0.0204055
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0203671
MYH14 myosin, heavy chain 14, non-muscle 0.0202671
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.0201472
SDC1 syndecan 1 0.0201165
VCL vinculin 0.0200611
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.0200254
SYNGR2 synaptogyrin 2 0.0200223
STK26 serine/threonine protein kinase 26 0.0199923
CCNI cyclin I 0.0199873
TFF3 trefoil factor 3 (intestinal) 0.0199795
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.0199351
TUFT1 tuftelin 1 0.0198992
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 0.0198758
ACTR10 actin-related protein 10 homolog (S. cerevisiae) 0.0198408
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 0.0198121
ATRN attractin 0.0197877
C14ORF132 chromosome 14 open reading frame 132 0.0195642
PUM2 pumilio RNA-binding family member 2 0.0195229
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.0195127
LMNA lamin A/C 0.0195103
JUND jun D proto-oncogene 0.0194147
SPNS1 spinster homolog 1 (Drosophila) 0.0193347
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.0193168
CXXC5 CXXC finger protein 5 0.0193027
ZNFX1 zinc finger, NFX1-type containing 1 0.0192676
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.0192248
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.0191917
CCDC47 coiled-coil domain containing 47 0.0191733
KRIT1 KRIT1, ankyrin repeat containing 0.019156
UBR2 ubiquitin protein ligase E3 component n-recognin 2 0.0191363
KDM2B lysine (K)-specific demethylase 2B 0.0190713
FOXK2 forkhead box K2 0.0190707
BCAP31 B-cell receptor-associated protein 31 0.0190654
NINL ninein-like 0.018944
MGP matrix Gla protein 0.0189393
WIPF1 WAS/WASL interacting protein family, member 1 0.0189166
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0188966
KMT2E lysine (K)-specific methyltransferase 2E 0.0188957
PICALM phosphatidylinositol binding clathrin assembly protein 0.0188558
STX12 syntaxin 12 0.018843
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 0.0188358
HELZ2 helicase with zinc finger 2, transcriptional coactivator 0.0187863
SNX2 sorting nexin 2 0.0187654
RPS12 ribosomal protein S12 0.0187357
PHTF1 putative homeodomain transcription factor 1 0.0186724
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.0186665
ABHD17C abhydrolase domain containing 17C 0.0185969
KLF6 Kruppel-like factor 6 0.0185573
PLXDC2 plexin domain containing 2 0.0185564
RPS27 ribosomal protein S27 0.0185545
LAPTM4B lysosomal protein transmembrane 4 beta 0.0185216
NCKAP5 NCK-associated protein 5 0.0184251
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.0184246
YIPF4 Yip1 domain family, member 4 0.0183765
MAN1A2 mannosidase, alpha, class 1A, member 2 0.018372
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.0183483
TMF1 TATA element modulatory factor 1 0.0183289
TOP2B topoisomerase (DNA) II beta 180kDa 0.0183062
GMPS guanine monphosphate synthase 0.0182185
DDB1 damage-specific DNA binding protein 1, 127kDa 0.0181981
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.0181675
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 0.0180915
SOS1 son of sevenless homolog 1 (Drosophila) 0.0180778
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.0180562
TTC39A tetratricopeptide repeat domain 39A 0.0180556
RAD23B RAD23 homolog B (S. cerevisiae) 0.01803
TPT1 tumor protein, translationally-controlled 1 0.0179838
RPL23 ribosomal protein L23 0.017982
MRTFA myocardin related transcription factor A 0.0179776
TRIR telomerase RNA component interacting RNase 0.0179738
NMD3 NMD3 ribosome export adaptor 0.017884
TRAPPC9 trafficking protein particle complex 9 0.0178815
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 0.0178793
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 0.0178235
SLC38A2 solute carrier family 38, member 2 0.0178046
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 0.0177752
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.0177396
RPL5 ribosomal protein L5 0.0177175
RPS7 ribosomal protein S7 0.0177101
CUTA cutA divalent cation tolerance homolog (E. coli) 0.0177044
ZNF217 zinc finger protein 217 0.0176952
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) 0.0176295
RNPS1 RNA binding protein S1, serine-rich domain 0.0176093
ATG5 autophagy related 5 0.0176072
TNRC6B trinucleotide repeat containing 6B 0.017591
AFF4 AF4/FMR2 family, member 4 0.017581
GPX4 glutathione peroxidase 4 0.0175555
RBM5 RNA binding motif protein 5 0.0175457
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 0.0174848
IRF2BPL interferon regulatory factor 2 binding protein-like 0.0174638
THEM6 thioesterase superfamily member 6 0.0174166
XKR6 XK, Kell blood group complex subunit-related family, member 6 0.0173881
HAGH hydroxyacylglutathione hydrolase 0.0173609
TMTC2 transmembrane and tetratricopeptide repeat containing 2 0.0172363
ZNF280D zinc finger protein 280D 0.017214
RPL26 ribosomal protein L26 0.0172057
HDAC8 histone deacetylase 8 0.0172027
ZFP91 ZFP91 zinc finger protein 0.0171646
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.0171266
DAZAP2 DAZ associated protein 2 0.0171098
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 0.0170667
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.0170654
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0170448
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.0170304
NLK nemo-like kinase 0.0170082
BCL2L1 BCL2-like 1 0.0169781
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0169348
LDAH lipid droplet associated hydrolase 0.0169035
BTG1 B-cell translocation gene 1, anti-proliferative 0.01689
RPL12 ribosomal protein L12 0.0168146
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.0167862
REEP3 receptor accessory protein 3 0.0167587
LYPD3 LY6/PLAUR domain containing 3 0.0167308
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.0167298
SF3B3 splicing factor 3b, subunit 3, 130kDa 0.0167296
ABHD2 abhydrolase domain containing 2 0.0167205
RABL6 RAB, member RAS oncogene family-like 6 0.0166961
RPSA ribosomal protein SA 0.0166648
NOTCH3 notch 3 0.0166645
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.0166582
RPS10 ribosomal protein S10 0.0166564
LOC102724023 ES1 protein homolog, mitochondrial 0.0166326
TLK2 tousled-like kinase 2 0.0166142
SVIL supervillin 0.0165978
KLHL24 kelch-like family member 24 0.016562
ATL2 atlastin GTPase 2 0.016519
SUN1 Sad1 and UNC84 domain containing 1 0.0164558
FOXN3 forkhead box N3 0.0164512
WDR73 WD repeat domain 73 0.0164334
CDH18 cadherin 18, type 2 0.0163844
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 0.0163801
SMAD3 SMAD family member 3 0.0163331
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.0163287
TAGLN2 transgelin 2 0.0162452
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.0162075
PTPRF protein tyrosine phosphatase, receptor type, F 0.0161339
RUFY2 RUN and FYVE domain containing 2 0.0161319
REST RE1-silencing transcription factor 0.0161142
MARVELD2 MARVEL domain containing 2 0.0160882
PDE8A phosphodiesterase 8A 0.0160769
TPD52 tumor protein D52 0.0160679
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 0.016058
NCOA1 nuclear receptor coactivator 1 0.01604
RPL31 ribosomal protein L31 0.0160233
PHACTR2 phosphatase and actin regulator 2 0.0160109
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.0160056
TM9SF3 transmembrane 9 superfamily member 3 0.015999
RPL35 ribosomal protein L35 0.0159805
SACK1B scaffolding CK1 anchoring protein B 0.0159637
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) 0.0159588
ACIN1 apoptotic chromatin condensation inducer 1 0.0159581
SIRT1 sirtuin 1 0.0159249
GABPB2 GA binding protein transcription factor, beta subunit 2 0.0159134
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.0158756
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.0158652
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.0158544
PPHLN1 periphilin 1 0.0158496
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.0158417
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0158099
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 0.0158027
SLC30A5 solute carrier family 30 (zinc transporter), member 5 0.0157897
ACYP2 acylphosphatase 2, muscle type 0.0157763
C6ORF141 chromosome 6 open reading frame 141 0.015759
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 0.0157339
TMTC3 transmembrane and tetratricopeptide repeat containing 3 0.0157246
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.0157228
ENTREP1 endosomal transmembrane epsin interactor 1 0.0156837
ZBTB10 zinc finger and BTB domain containing 10 0.0156376
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.0156153
NCOA4 nuclear receptor coactivator 4 0.0154824
PTPRA protein tyrosine phosphatase, receptor type, A 0.0154664
RBMS1 RNA binding motif, single stranded interacting protein 1 0.0154485
BCAS2 breast carcinoma amplified sequence 2 0.0154314
SSR4 signal sequence receptor, delta 0.0154231
HRNR hornerin 0.015423
CLU clusterin 0.0154137
TBC1D5 TBC1 domain family, member 5 0.0153941
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0153904
RPL36A ribosomal protein L36a 0.0153889
VEZF1 vascular endothelial zinc finger 1 0.0153442
RAB40C RAB40C, member RAS oncogene family 0.0153404
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.015288
SLC9D1 solute carrier family 9 member D1 0.015269
PIGX phosphatidylinositol glycan anchor biosynthesis, class X 0.0152294
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum) 0.0152057
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.0151756
PTGR1 prostaglandin reductase 1 0.0151683
RPLP2 ribosomal protein, large, P2 0.015166
COX6C cytochrome c oxidase subunit VIc 0.0151385
SAMD8 sterile alpha motif domain containing 8 0.0151046
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.0151022
RPL7 ribosomal protein L7 0.0150718
SEC24A SEC24 family member A 0.0150609
ARRDC1 arrestin domain containing 1 0.0150602
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 0.0150554
LRRC58 leucine rich repeat containing 58 0.0150316
PTBP1 polypyrimidine tract binding protein 1 0.0150176
ERCC6 excision repair cross-complementation group 6 0.0149587
EAPP E2F-associated phosphoprotein 0.0149389
FAM234A family with sequence similarity 234 member A 0.0149288
BCAM basal cell adhesion molecule (Lutheran blood group) 0.0149072
RPL6 ribosomal protein L6 0.0148959
MED12 mediator complex subunit 12 0.0148937
RPN1 ribophorin I 0.0148626
TTC6 tetratricopeptide repeat domain 6 0.0148597
CHPF chondroitin polymerizing factor 0.0148331
EFCAB14 EF-hand calcium binding domain 14 0.014816
ANXA2 annexin A2 0.0148145
SNX24 sorting nexin 24 0.0147993
DSTN destrin (actin depolymerizing factor) 0.0147863
SLC35H1 solute carrier family 35 member H1 0.0147745
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0147102
OPN3 opsin 3 0.0146766
SNX6 sorting nexin 6 0.0146407
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.0146183
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit 0.0146149
AFF1 AF4/FMR2 family, member 1 0.0145805
PARD3B par-3 family cell polarity regulator beta 0.0145776
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa 0.0145563
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 0.0145447
LATS2 large tumor suppressor kinase 2 0.0144665
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 0.0143847
CERCAM cerebral endothelial cell adhesion molecule 0.0143843
THRB thyroid hormone receptor, beta 0.01435
PHTF2 putative homeodomain transcription factor 2 0.0143465
RSU1 Ras suppressor protein 1 0.0143454
MXD4 MAX dimerization protein 4 0.0143271
ABI1 abl-interactor 1 0.0142988
COX7C cytochrome c oxidase subunit VIIc 0.0142927
EMP2 epithelial membrane protein 2 0.0142813
UGCG UDP-glucose ceramide glucosyltransferase 0.0142609
ZNF106 zinc finger protein 106 0.0142536
HHAT hedgehog acyltransferase 0.0142334
TXNRD1 thioredoxin reductase 1 0.0142256
PTPN14 protein tyrosine phosphatase, non-receptor type 14 0.0142236
VAV3 vav 3 guanine nucleotide exchange factor 0.01418
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2 0.0141596
RNASET2 ribonuclease T2 0.014155
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.0141072
RCAN2 regulator of calcineurin 2 0.014085
IGFBP4 insulin-like growth factor binding protein 4 0.0140842
PARN poly(A)-specific ribonuclease 0.0140307
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 0.0139974
CEP350 centrosomal protein 350kDa 0.013982
TNPO1 transportin 1 0.0139813
KCNK15 potassium channel, two pore domain subfamily K, member 15 0.013981
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 0.0139698
SNX27 sorting nexin family member 27 0.0139698
GOLPH3 golgi phosphoprotein 3 (coat-protein) 0.0139507
ZFAND5 zinc finger, AN1-type domain 5 0.0139385
MYO9A myosin IXA 0.0139249
RPS9 ribosomal protein S9 0.0139002
SBF2 SET binding factor 2 0.0137207
TMX4 thioredoxin-related transmembrane protein 4 0.0137164
RAD23A RAD23 homolog A (S. cerevisiae) 0.0136662
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 0.0136638
CYB561 cytochrome b561 0.0136295
EIF1 eukaryotic translation initiation factor 1 0.0136127
SMYD2 SET and MYND domain containing 2 0.0136106
SRSF10 serine/arginine-rich splicing factor 10 0.0135951
PRKCA protein kinase C, alpha 0.013595
LMTK2 lemur tyrosine kinase 2 0.0135852
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 0.0135751
MUC16 mucin 16, cell surface associated 0.0135694
SAMD9 sterile alpha motif domain containing 9 0.0135676
RGS6 regulator of G-protein signaling 6 0.0135369
RPS25 ribosomal protein S25 0.0134949
SECISBP2L SECIS binding protein 2-like 0.0134943
ERGIC2 ERGIC and golgi 2 0.0134668
ELOVL7 ELOVL fatty acid elongase 7 0.0134524
CCDC6 coiled-coil domain containing 6 0.0134329
FBXO32 F-box protein 32 0.0134225
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) 0.0134011
RORA RAR-related orphan receptor A 0.0132623
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.0132447
GREB1L growth regulation by estrogen in breast cancer-like 0.0132438
MEF2D myocyte enhancer factor 2D 0.0132328
VGLL4 vestigial-like family member 4 0.0132257
RPL14 ribosomal protein L14 0.013223
RNASEK ribonuclease, RNase K 0.0131997
FGFR2 fibroblast growth factor receptor 2 0.0131349
FDX1 ferredoxin 1 0.0131212
MARVELD3 MARVEL domain containing 3 0.0130991
ATXN1 ataxin 1 0.0130945
LPP LIM domain containing preferred translocation partner in lipoma 0.0130795
FLII flightless I homolog (Drosophila) 0.0130637
SPRED2 sprouty-related, EVH1 domain containing 2 0.0130585
WASHC5 WASH complex subunit 5 0.0130421
ZNF91 zinc finger protein 91 0.0130352
STOM stomatin 0.0130119
LPGAT1 lysophosphatidylglycerol acyltransferase 1 0.0130036
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.0129961
NSUN6 NOP2/Sun domain family, member 6 0.0129953
USP34 ubiquitin specific peptidase 34 0.0129715
RANBP2 RAN binding protein 2 0.0129679
GLRA3 glycine receptor, alpha 3 0.012966
GRN granulin 0.0129657
ZNF561 zinc finger protein 561 0.0129586
GPR137 G protein-coupled receptor 137 0.0129426
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0129252
OSBPL9 oxysterol binding protein-like 9 0.0129247
ARID5B AT rich interactive domain 5B (MRF1-like) 0.0129195
TMEM117 transmembrane protein 117 0.0128967
TCERG1 transcription elongation regulator 1 0.0128448
AHCYL1 adenosylhomocysteinase-like 1 0.0128399
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 0.0128384
CLMN calmin (calponin-like, transmembrane) 0.0128334
CCNL2 cyclin L2 0.0128095
H2BC8 H2B clustered histone 8 0.0127536
PRKCSH protein kinase C substrate 80K-H 0.012753
SETD5 SET domain containing 5 0.012737
CDKL5 cyclin-dependent kinase-like 5 0.012711
RBM17 RNA binding motif protein 17 0.0126693
ZNF804B zinc finger protein 804B 0.0126632
SKP1 S-phase kinase-associated protein 1 0.0126568
POLR1D polymerase (RNA) I polypeptide D, 16kDa 0.0126058
VEGFB vascular endothelial growth factor B 0.0125716
PFN1 profilin 1 0.01257
ZDHHC20 zinc finger, DHHC-type containing 20 0.0125687

decreased expression

Symbol Name Standardized Value
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.134865
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.125072
TUBD1 tubulin, delta 1 -0.0793602
JARID2 jumonji, AT rich interactive domain 2 -0.0755247
NCOA3 nuclear receptor coactivator 3 -0.071178
SULF2 sulfatase 2 -0.0690962
PRKCE protein kinase C, epsilon -0.0687376
PBX3 pre-B-cell leukemia homeobox 3 -0.0680265
IFI6 interferon, alpha-inducible protein 6 -0.0663985
ESR1 estrogen receptor 1 -0.0660074
RAD51B RAD51 paralog B -0.0630047
MKI67 marker of proliferation Ki-67 -0.062848
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.061862
ANKRD11 ankyrin repeat domain 11 -0.0598314
CTNND2 catenin (cadherin-associated protein), delta 2 -0.0595204
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.056522
SRPK2 SRSF protein kinase 2 -0.0547626
TFF1 trefoil factor 1 -0.0547248
FAF1 Fas (TNFRSF6) associated factor 1 -0.0521746
SKA2 spindle and kinetochore associated complex subunit 2 -0.0517863
PRRC2B proline-rich coiled-coil 2B -0.0515414
EPHA4 EPH receptor A4 -0.0493727
IGF1R insulin-like growth factor 1 receptor -0.0490086
MBD5 methyl-CpG binding domain protein 5 -0.0485058
SIL1 SIL1 nucleotide exchange factor -0.0484231
EVL Enah/Vasp-like -0.0482385
SPIDR scaffolding protein involved in DNA repair -0.0472398
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 -0.0463542
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.045925
BIRC6 baculoviral IAP repeat containing 6 -0.0451448
GPC6 glypican 6 -0.0443947
GRHL2 grainyhead-like 2 (Drosophila) -0.044315
TMEM164 transmembrane protein 164 -0.0433899
PRR11 proline rich 11 -0.0433096
GSE1 Gse1 coiled-coil protein -0.0430249
TMEM178B transmembrane protein 178B -0.0430064
RANBP17 RAN binding protein 17 -0.0425068
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0420182
PAN3 PAN3 poly(A) specific ribonuclease subunit -0.0414703
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.040149
NFX1 nuclear transcription factor, X-box binding 1 -0.0398426
DCAF7 DDB1 and CUL4 associated factor 7 -0.0395006
RBM39 RNA binding motif protein 39 -0.0394525
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0390431
CDK13 cyclin-dependent kinase 13 -0.0388642
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.0386376
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 -0.0381599
TRIM33 tripartite motif containing 33 -0.0374586
GTF2IRD1 GTF2I repeat domain containing 1 -0.0360549
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.0356751
PTRH2 peptidyl-tRNA hydrolase 2 -0.0351572
TMEM64 transmembrane protein 64 -0.0349802
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -0.0349268
PPP4R3A protein phosphatase 4 regulatory subunit 3A -0.0347926
SRSF4 serine/arginine-rich splicing factor 4 -0.0345801
PPP1R13B protein phosphatase 1, regulatory subunit 13B -0.0339277
RBM6 RNA binding motif protein 6 -0.0337429
DOCK1 dedicator of cytokinesis 1 -0.0329644
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0328726
CADPS2 Ca++-dependent secretion activator 2 -0.0328617
HIP1 huntingtin interacting protein 1 -0.032017
ZZZ3 zinc finger, ZZ-type containing 3 -0.0319133
EIF4B eukaryotic translation initiation factor 4B -0.0318597
MSI2 musashi RNA-binding protein 2 -0.0317571
TMOD3 tropomodulin 3 (ubiquitous) -0.0316816
KYNU kynureninase -0.0316411
AMBRA1 autophagy/beclin-1 regulator 1 -0.0316113
MROH1 maestro heat-like repeat family member 1 -0.03149
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB -0.0313464
ARID4B AT rich interactive domain 4B (RBP1-like) -0.030875
RERG RAS-like, estrogen-regulated, growth inhibitor -0.0308102
POTEF POTE ankyrin domain family, member F -0.0305279
GFRA1 GDNF family receptor alpha 1 -0.0299865
SLTM SAFB-like, transcription modulator -0.0298316
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 -0.0296919
PPP6R3 protein phosphatase 6, regulatory subunit 3 -0.0295207
MYO6 myosin VI -0.0292218
SCAPER S-phase cyclin A-associated protein in the ER -0.0292011
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -0.0289962
SEPTIN9 septin 9 -0.0286923
EIF3B eukaryotic translation initiation factor 3, subunit B -0.0285881
TPD52L1 tumor protein D52-like 1 -0.028523
EHBP1 EH domain binding protein 1 -0.0285071
GLG1 golgi glycoprotein 1 -0.0284747
DIDO1 death inducer-obliterator 1 -0.0283866
NFIB nuclear factor I/B -0.0282201
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0281007
BRCA1 breast cancer 1, early onset -0.0280186
CANX calnexin -0.0278508
RPS6 ribosomal protein S6 -0.0277464
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0277295
FBXL17 F-box and leucine-rich repeat protein 17 -0.0277252
UVRAG UV radiation resistance associated -0.0277166
OSBPL10 oxysterol binding protein-like 10 -0.0276837
TPI1 triosephosphate isomerase 1 -0.0276222
CHD4 chromodomain helicase DNA binding protein 4 -0.0276066
NRIP1 nuclear receptor interacting protein 1 -0.0275042
SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10 -0.0274952
PUS7 pseudouridylate synthase 7 (putative) -0.0274235
CAPZB capping protein (actin filament) muscle Z-line, beta -0.0274133
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.027402
EIF3A eukaryotic translation initiation factor 3, subunit A -0.0272442
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0270325
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 -0.0270178
WAC WW domain containing adaptor with coiled-coil -0.0268403
CENPF centromere protein F, 350/400kDa -0.0266439
DPP8 dipeptidyl-peptidase 8 -0.026574
HM13 histocompatibility (minor) 13 -0.0264222
CENPP centromere protein P -0.0262936
IQCB1 IQ motif containing B1 -0.0260069
GRB2 growth factor receptor-bound protein 2 -0.0259641
EXOC4 exocyst complex component 4 -0.0259347
STX8 syntaxin 8 -0.0258945
ERBB4 erb-b2 receptor tyrosine kinase 4 -0.0257577
RBM4 RNA binding motif protein 4 -0.0255779
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -0.0255434
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.0255101
MBD4 methyl-CpG binding domain protein 4 -0.0252522
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.0251896
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -0.0251732
ALMS1 Alstrom syndrome protein 1 -0.0251402
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.0251032
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha -0.0250914
MRTFB myocardin related transcription factor B -0.0250615
TET2 tet methylcytosine dioxygenase 2 -0.0250423
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -0.0250033
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.024973
STAU1 staufen double-stranded RNA binding protein 1 -0.0249348
ISG15 ISG15 ubiquitin-like modifier -0.0247271
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) -0.0245421
KMT2C lysine (K)-specific methyltransferase 2C -0.0245226
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -0.0244055
KIF5B kinesin family member 5B -0.0243703
GAN gigaxonin -0.0242385
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.0242012
CKAP5 cytoskeleton associated protein 5 -0.0241972
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.0241696
C21ORF58 chromosome 21 open reading frame 58 -0.0241117
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 -0.0240992
C1ORF21 chromosome 1 open reading frame 21 -0.0240898
PCNT pericentrin -0.0239077
PCBP3 poly(rC) binding protein 3 -0.0238776
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -0.0238541
ZNF721 zinc finger protein 721 -0.0238363
PHF21A PHD finger protein 21A -0.023781
ZNF609 zinc finger protein 609 -0.023694
RAD21 RAD21 homolog (S. pombe) -0.0236576
ERC1 ELKS/RAB6-interacting/CAST family member 1 -0.0236519
LOC112694756 uncharaterized LOC112694756 -0.0236209
LARP1 La ribonucleoprotein domain family, member 1 -0.023465
NUP107 nucleoporin 107kDa -0.0233642
COPE coatomer protein complex, subunit epsilon -0.0233227
SIN3A SIN3 transcription regulator family member A -0.0233194
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -0.023313
TASP1 taspase, threonine aspartase, 1 -0.023275
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -0.0232628
VSIG10 V-set and immunoglobulin domain containing 10 -0.0232366
FANCI Fanconi anemia, complementation group I -0.0231926
TRIP12 thyroid hormone receptor interactor 12 -0.0231804
RBM47 RNA binding motif protein 47 -0.023164
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) -0.02316
XPO1 exportin 1 -0.023096
TRAF3 TNF receptor-associated factor 3 -0.0230477
LRIF1 ligand dependent nuclear receptor interacting factor 1 -0.0230458
GAPVD1 GTPase activating protein and VPS9 domains 1 -0.0230398
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.0230154
XPO4 exportin 4 -0.0229353
BPTF bromodomain PHD finger transcription factor -0.022922
ZNF652 zinc finger protein 652 -0.0229127
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 -0.0228407
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0228048
PRR14L proline rich 14-like -0.0228039
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.0227877
MYO1E myosin IE -0.0227768
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 -0.0227385
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 -0.0227304
RBL1 retinoblastoma-like 1 -0.0226953
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 -0.0225407
MCM7 minichromosome maintenance complex component 7 -0.0225373
ATRNL1 attractin-like 1 -0.0224181
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.0224147
SMYD3 SET and MYND domain containing 3 -0.022335
ADAM10 ADAM metallopeptidase domain 10 -0.0222998
SND1 staphylococcal nuclease and tudor domain containing 1 -0.0222784
HP1BP3 heterochromatin protein 1, binding protein 3 -0.0222561
ECE1 endothelin converting enzyme 1 -0.0221271
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -0.0221238
BCAS4 breast carcinoma amplified sequence 4 -0.0220776
CYRIB CYFIP related Rac1 interactor B -0.022056
SFPQ splicing factor proline/glutamine-rich -0.0220274
ZNF407 zinc finger protein 407 -0.0219402
JMJD1C jumonji domain containing 1C -0.0218976
NUP160 nucleoporin 160kDa -0.0218752
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 -0.0218734
C6ORF62 chromosome 6 open reading frame 62 -0.0218531
EXOC6 exocyst complex component 6 -0.021848
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 -0.0218394
TRIO trio Rho guanine nucleotide exchange factor -0.0217591
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 -0.0217274
PI4KB phosphatidylinositol 4-kinase, catalytic, beta -0.0215722
TRAPPC10 trafficking protein particle complex 10 -0.021467
SCAI suppressor of cancer cell invasion -0.0213823
AKAP13 A kinase (PRKA) anchor protein 13 -0.0213709
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 -0.0213125
FAM13B family with sequence similarity 13, member B -0.0213011
GMDS GDP-mannose 4,6-dehydratase -0.0212552
CAMKMT calmodulin-lysine N-methyltransferase -0.0212485
RCOR1 REST corepressor 1 -0.0210495
STYXL1 serine/threonine/tyrosine interacting-like 1 -0.0209675
AREG amphiregulin -0.0209282
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0208596
SMIM44 small integral membrane protein 44 -0.0208172
JPT1 Jupiter microtubule associated homolog 1 -0.0208124
PRLR prolactin receptor -0.020779
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -0.0207702
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -0.0207141
TLK1 tousled-like kinase 1 -0.0207137
ILF3 interleukin enhancer binding factor 3, 90kDa -0.0206694
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) -0.0205872
MTMR3 myotubularin related protein 3 -0.0205862
PATJ PATJ crumbs cell polarity complex component -0.0205758
ZNF251 zinc finger protein 251 -0.0205265
TLN2 talin 2 -0.0204035
ESRP1 epithelial splicing regulatory protein 1 -0.0202668
REPS1 RALBP1 associated Eps domain containing 1 -0.0202152
CELF1 CUGBP, Elav-like family member 1 -0.0201846
CHD9 chromodomain helicase DNA binding protein 9 -0.0201033
DLG1 discs, large homolog 1 (Drosophila) -0.0199664
IFI27 interferon, alpha-inducible protein 27 -0.0199633
FNBP4 formin binding protein 4 -0.019951
GREB1 growth regulation by estrogen in breast cancer 1 -0.0198911
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0198515
GAB2 GRB2-associated binding protein 2 -0.0196873
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -0.0196728
RAD18 RAD18 E3 ubiquitin protein ligase -0.0196533
SON SON DNA binding protein -0.0195762
BTBD7 BTB (POZ) domain containing 7 -0.0194832
CHEK2 checkpoint kinase 2 -0.019478
RAB10 RAB10, member RAS oncogene family -0.019451
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0193857
FAM120A family with sequence similarity 120A -0.0193782
TSC22D2 TSC22 domain family, member 2 -0.0193545
PLK2 polo-like kinase 2 -0.0193201
RANBP9 RAN binding protein 9 -0.019311
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -0.0193078
SOS2 son of sevenless homolog 2 (Drosophila) -0.0192745
ZNF277 zinc finger protein 277 -0.0192342
CEP192 centrosomal protein 192kDa -0.0192338
RABGAP1L RAB GTPase activating protein 1-like -0.0191938
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 -0.0191691
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C -0.0191223
SPG11 spastic paraplegia 11 (autosomal recessive) -0.0191148
LRPPRC leucine-rich pentatricopeptide repeat containing -0.0191098
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A -0.0190924
SMG6 SMG6 nonsense mediated mRNA decay factor -0.0190643
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 -0.0190518
ZNF124 zinc finger protein 124 -0.0190258
KPNA1 karyopherin alpha 1 (importin alpha 5) -0.0189356
GTF2I general transcription factor IIi -0.0189116
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) -0.0188734
VRK1 vaccinia related kinase 1 -0.0188329
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0187916
MEF2A myocyte enhancer factor 2A -0.0187173
PRPF3 pre-mRNA processing factor 3 -0.0187002
ARID1B AT rich interactive domain 1B (SWI1-like) -0.0186951
ATXN7L1 ataxin 7-like 1 -0.0186561
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0186218
GOLGA2 golgin A2 -0.0185516
RBM15 RNA binding motif protein 15 -0.0185287
PTGES2 prostaglandin E synthase 2 -0.0185235
FANCC Fanconi anemia, complementation group C -0.0185132
PACS2 phosphofurin acidic cluster sorting protein 2 -0.0184793
CLIC1 chloride intracellular channel 1 -0.018437
LARP4B La ribonucleoprotein domain family, member 4B -0.0184096
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -0.0183625
LDLRAD4 low density lipoprotein receptor class A domain containing 4 -0.0182942
SHANK2 SH3 and multiple ankyrin repeat domains 2 -0.01828
PDS5A PDS5 cohesin associated factor A -0.0182606
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.0182444
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0182251
ADARB1 adenosine deaminase, RNA-specific, B1 -0.0182127
MECOM MDS1 and EVI1 complex locus -0.0181207
CLTA clathrin, light chain A -0.0180652
WWC1 WW and C2 domain containing 1 -0.0180082
PCM1 pericentriolar material 1 -0.0179737
NANS N-acetylneuraminic acid synthase -0.0179616
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 -0.0179404
NVL nuclear VCP-like -0.0178111
TMCC1 transmembrane and coiled-coil domain family 1 -0.0178108
SLF2 SMC5-SMC6 complex localization factor 2 -0.0178007
PITPNB phosphatidylinositol transfer protein, beta -0.0177864
MORF4L1 mortality factor 4 like 1 -0.0177845
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0177831
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) -0.0177829
MLEC malectin -0.0177827
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 -0.0177718
VWA8 von Willebrand factor A domain containing 8 -0.0177604
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 -0.0177508
MAPT microtubule-associated protein tau -0.0177503
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.0177198
CMYA5 cardiomyopathy associated 5 -0.0177192
CBFB core-binding factor, beta subunit -0.0176971
IFT88 intraflagellar transport 88 -0.0176809
RPL27A ribosomal protein L27a -0.0176587
AFG3L2 AFG3-like AAA ATPase 2 -0.0176319
VAV2 vav 2 guanine nucleotide exchange factor -0.0176142
ZMYND8 zinc finger, MYND-type containing 8 -0.0175436
SBNO1 strawberry notch homolog 1 (Drosophila) -0.0175208
DNM2 dynamin 2 -0.017517
PIKFYVE phosphoinositide kinase, FYVE finger containing -0.017485
TRAP1 TNF receptor-associated protein 1 -0.0174831
ATP5MF ATP synthase membrane subunit f -0.0174699
THSD4 thrombospondin, type I, domain containing 4 -0.0174603
TMEM150C transmembrane protein 150C -0.0174511
RAB31 RAB31, member RAS oncogene family -0.0174199
RAB11FIP3 RAB11 family interacting protein 3 (class II) -0.0174138
PARP4 poly (ADP-ribose) polymerase family, member 4 -0.0173865
FRAS1 Fraser extracellular matrix complex subunit 1 -0.0173509
CLOCK clock circadian regulator -0.0173475
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific -0.0172875
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.0172776
PIEZO1 piezo-type mechanosensitive ion channel component 1 -0.0172666
MGMT O-6-methylguanine-DNA methyltransferase -0.0172422
ADD1 adducin 1 (alpha) -0.0171898
STK10 serine/threonine kinase 10 -0.0171671
HNRNPK heterogeneous nuclear ribonucleoprotein K -0.0171144
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 -0.0170692
ADI1 acireductone dioxygenase 1 -0.0170363
AKAP8L A kinase (PRKA) anchor protein 8-like -0.0170271
ZNF710 zinc finger protein 710 -0.0170185
RAB7A RAB7A, member RAS oncogene family -0.016946
TMPRSS4 transmembrane protease, serine 4 -0.0168492
METTL2A methyltransferase like 2A -0.0168259
TM9SF4 transmembrane 9 superfamily protein member 4 -0.016791
MCM3AP minichromosome maintenance complex component 3 associated protein -0.0166987
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -0.0166561
NEMF nuclear export mediator factor -0.0166447
KCNK6 potassium channel, two pore domain subfamily K, member 6 -0.0166145
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.0166006
RABGAP1 RAB GTPase activating protein 1 -0.0165874
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -0.0165751
AKAP10 A kinase (PRKA) anchor protein 10 -0.0165702
TRRAP transformation/transcription domain-associated protein -0.0165687
TBL1X transducin (beta)-like 1X-linked -0.0165181
ARFIP1 ADP-ribosylation factor interacting protein 1 -0.0165037
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) -0.0165016
UBE3A ubiquitin protein ligase E3A -0.0164915
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) -0.0164419
RNF216 ring finger protein 216 -0.0164032
RAB21 RAB21, member RAS oncogene family -0.0163923
SRRM2 serine/arginine repetitive matrix 2 -0.0163629
PGPEP1 pyroglutamyl-peptidase I -0.0163276
SETX senataxin -0.0163157
PTEN phosphatase and tensin homolog -0.0163151
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) -0.0163102
TTC39C tetratricopeptide repeat domain 39C -0.0162835
DNPEP aspartyl aminopeptidase -0.0162731
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein -0.0162655
EXPH5 exophilin 5 -0.0162544
ARHGAP11B Rho GTPase activating protein 11B -0.0162477
FBXO11 F-box protein 11 -0.016155
CDCA5 cell division cycle associated 5 -0.0161516
GYS1 glycogen synthase 1 (muscle) -0.0161147
PROSER3 proline and serine rich 3 -0.0161021
ANKRD13C ankyrin repeat domain 13C -0.0160818
IGSF1 immunoglobulin superfamily, member 1 -0.0160787
EMC8 ER membrane protein complex subunit 8 -0.0160155
FTSJ3 FtsJ homolog 3 (E. coli) -0.015997
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 -0.0159886
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 -0.0159106
MDN1 MDN1, midasin homolog (yeast) -0.0158964
FAM222B family with sequence similarity 222, member B -0.0158935
GPHN gephyrin -0.0158636
DDHD1 DDHD domain containing 1 -0.0158232
WWC2 WW and C2 domain containing 2 -0.0158215
NUDC nudC nuclear distribution protein -0.0158155
PRIM2 primase, DNA, polypeptide 2 (58kDa) -0.0158088
UBA2 ubiquitin-like modifier activating enzyme 2 -0.015802
LRP1B low density lipoprotein receptor-related protein 1B -0.0157998
TASOR2 transcription activation suppressor family member 2 -0.0157886
TMSB10 thymosin beta 10 -0.0157708
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.0157583
PLXNA4 plexin A4 -0.0157567
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.0157555
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0157553
KDM2A lysine (K)-specific demethylase 2A -0.015716
ANKRD50 ankyrin repeat domain 50 -0.0156847
LRMDA leucine rich melanocyte differentiation associated -0.0156782
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 -0.0156637
ATF7IP activating transcription factor 7 interacting protein -0.0156591
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B -0.01565
ENAH enabled homolog (Drosophila) -0.0156443
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.0156253
TBK1 TANK-binding kinase 1 -0.0156032
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -0.0156008
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.0155829
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 -0.015546
EPN2 epsin 2 -0.0155406
GALC galactosylceramidase -0.0155103
MAP3K20 mitogen-activated protein kinase kinase kinase 20 -0.0154961
ZRANB3 zinc finger, RAN-binding domain containing 3 -0.0154799
WWP1 WW domain containing E3 ubiquitin protein ligase 1 -0.0154704
HMMR hyaluronan-mediated motility receptor (RHAMM) -0.0153646
ERN1 endoplasmic reticulum to nucleus signaling 1 -0.0153486
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -0.0153396
CMSS1 cms1 ribosomal small subunit homolog (yeast) -0.0153045
CLASP1 cytoplasmic linker associated protein 1 -0.0153043
DOP1B DOP1 leucine zipper like protein B -0.0153008
ZNF638 zinc finger protein 638 -0.0152993
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -0.0152748
TKT transketolase -0.0152599
KIF1B kinesin family member 1B -0.0152047
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -0.0152033
BAZ1A bromodomain adjacent to zinc finger domain, 1A -0.0151704
KDM3B lysine (K)-specific demethylase 3B -0.0151526
OTUD5 OTU deubiquitinase 5 -0.0151443
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 -0.0151307
TTC19 tetratricopeptide repeat domain 19 -0.015123
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -0.0151144
CNOT2 CCR4-NOT transcription complex, subunit 2 -0.015107
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma -0.0151064
NIPBL Nipped-B homolog (Drosophila) -0.0151031
PTPN11 protein tyrosine phosphatase, non-receptor type 11 -0.0150333
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -0.0150217
TAOK1 TAO kinase 1 -0.0150029
TRPS1 trichorhinophalangeal syndrome I -0.0149991
KIAA0319L KIAA0319-like -0.0149957
AFAP1 actin filament associated protein 1 -0.0149698
ENO1 enolase 1, (alpha) -0.0149603
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -0.014952
TOP6BL TOP6B like initiator of meiotic double strand breaks -0.0149498
CRABP2 cellular retinoic acid binding protein 2 -0.0149408
STXBP4 syntaxin binding protein 4 -0.0149191
GARNL3 GTPase activating Rap/RanGAP domain-like 3 -0.014918
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -0.0149036
ZC3H18 zinc finger CCCH-type containing 18 -0.0148988
CCDC93 coiled-coil domain containing 93 -0.0148861
SPOPL speckle-type POZ protein-like -0.0148817
TTC27 tetratricopeptide repeat domain 27 -0.0148765
THRAP3 thyroid hormone receptor associated protein 3 -0.0148653
GOSR1 golgi SNAP receptor complex member 1 -0.0148606
FAM168B family with sequence similarity 168, member B -0.0148442
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0148328
LCOR ligand dependent nuclear receptor corepressor -0.0148208
NUP155 nucleoporin 155kDa -0.0148035
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -0.0147901
TMEM245 transmembrane protein 245 -0.0147851
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 -0.0147813
R3HDM1 R3H domain containing 1 -0.0147744
LCORL ligand dependent nuclear receptor corepressor-like -0.0147538
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta -0.0147524
NAP1L1 nucleosome assembly protein 1-like 1 -0.014743
RNF169 ring finger protein 169 -0.0147361
FTO fat mass and obesity associated -0.0147211
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -0.0147119
NT5C3A 5'-nucleotidase, cytosolic IIIA -0.0147102
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.0146922
C6ORF89 chromosome 6 open reading frame 89 -0.0146823
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle -0.0146725
CYBA cytochrome b-245, alpha polypeptide -0.0146697
SAMD12 sterile alpha motif domain containing 12 -0.0146432
OAZ1 ornithine decarboxylase antizyme 1 -0.0146183
IFITM3 interferon induced transmembrane protein 3 -0.0146107
ASCC2 activating signal cointegrator 1 complex subunit 2 -0.0145944
STIL SCL/TAL1 interrupting locus -0.0145926
SOGA1 suppressor of glucose, autophagy associated 1 -0.0145926
ADCY9 adenylate cyclase 9 -0.0145882
NOP58 NOP58 ribonucleoprotein -0.0145782
ZNF331 zinc finger protein 331 -0.0145644
CDC42SE2 CDC42 small effector 2 -0.0145536
GLI3 GLI family zinc finger 3 -0.014546
GABPB1 GA binding protein transcription factor, beta subunit 1 -0.0145396
PRMT7 protein arginine methyltransferase 7 -0.014535
ZNF37A zinc finger protein 37A -0.0145332
NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa -0.0144304
POU2F1 POU class 2 homeobox 1 -0.0144207
ZFR zinc finger RNA binding protein -0.0144113
LMNB1 lamin B1 -0.0143835
NEO1 neogenin 1 -0.0143756
AP1G1 adaptor-related protein complex 1, gamma 1 subunit -0.0143327
CLSTN1 calsyntenin 1 -0.0143117
DERL1 derlin 1 -0.0143076
NTN1 netrin 1 -0.014281
PTMA prothymosin, alpha -0.01422
SCAF8 SR-related CTD-associated factor 8 -0.014159
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -0.0141252
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.0141243
ZMPSTE24 zinc metallopeptidase STE24 -0.0140973
UST uronyl-2-sulfotransferase -0.0140947
SNF8 SNF8, ESCRT-II complex subunit -0.0140902
TNRC6A trinucleotide repeat containing 6A -0.0140881
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -0.0140842
ATAD2 ATPase family, AAA domain containing 2 -0.0140619
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.0140578
CPEB3 cytoplasmic polyadenylation element binding protein 3 -0.0140562
SSR1 signal sequence receptor, alpha -0.0140181
UBB ubiquitin B -0.014001
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0139987
MPHOSPH9 M-phase phosphoprotein 9 -0.0139886
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit -0.0139839