MCF7_SGI-1776 free base_10µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description SGI-1776 free base 10µM perturbation in MCF7 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the MCF7_SGI-1776 free base_10µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.251231
IGF1R insulin-like growth factor 1 receptor 0.192682
DSCAM Down syndrome cell adhesion molecule 0.158092
BCAS3 breast carcinoma amplified sequence 3 0.108683
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 0.0990056
PAWR PRKC, apoptosis, WT1, regulator 0.0983423
LDLR low density lipoprotein receptor 0.0846256
MED13L mediator complex subunit 13-like 0.0764872
MED13 mediator complex subunit 13 0.0700321
SLC38A1 solute carrier family 38, member 1 0.067439
TRPS1 trichorhinophalangeal syndrome I 0.0667522
NRP1 neuropilin 1 0.0647054
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 0.0634687
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.0622234
MALRD1 MAM and LDL receptor class A domain containing 1 0.0620207
SPTSSB serine palmitoyltransferase, small subunit B 0.0598319
SVIL supervillin 0.058819
RGS6 regulator of G-protein signaling 6 0.0580163
DTNA dystrobrevin, alpha 0.0574069
TPM4 tropomyosin 4 0.0563101
CLIC4 chloride intracellular channel 4 0.0541264
DST dystonin 0.0536956
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0534119
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 0.0532332
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0505372
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.050518
CUX1 cut-like homeobox 1 0.0494292
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.049033
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0487186
MLPH melanophilin 0.0486308
TFF1 trefoil factor 1 0.04828
PTPRK protein tyrosine phosphatase, receptor type, K 0.0476327
RHOBTB3 Rho-related BTB domain containing 3 0.0459053
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.0456131
GOLGB1 golgin B1 0.0449362
DCDC2 doublecortin domain containing 2 0.0446307
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.0441883
COX6C cytochrome c oxidase subunit VIc 0.0434629
ITGB5 integrin, beta 5 0.0429559
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 0.0425674
BASP1 brain abundant, membrane attached signal protein 1 0.0424913
TRIM37 tripartite motif containing 37 0.0413995
RUNX1 runt-related transcription factor 1 0.0413674
CEMIP2 cell migration inducing hyaluronidase 2 0.0405502
DSTN destrin (actin depolymerizing factor) 0.0402518
MRPL13 mitochondrial ribosomal protein L13 0.0399056
RPS9 ribosomal protein S9 0.0395056
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.0385768
RBM47 RNA binding motif protein 47 0.0384793
GLCCI1 glucocorticoid induced 1 0.0382023
OSBPL9 oxysterol binding protein-like 9 0.0373431
NAV1 neuron navigator 1 0.0371963
TIMP3 TIMP metallopeptidase inhibitor 3 0.0369037
WIPF1 WAS/WASL interacting protein family, member 1 0.0366965
KDM5B lysine (K)-specific demethylase 5B 0.0365721
PALLD palladin, cytoskeletal associated protein 0.0362635
VCL vinculin 0.0345988
HEATR6 HEAT repeat containing 6 0.0344902
ALCAM activated leukocyte cell adhesion molecule 0.0339002
GREB1 growth regulation by estrogen in breast cancer 1 0.0337637
EEF2 eukaryotic translation elongation factor 2 0.0335469
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.0334481
KRT80 keratin 80, type II 0.0332355
LONRF2 LON peptidase N-terminal domain and ring finger 2 0.0332307
DHCR7 7-dehydrocholesterol reductase 0.0332097
MVD mevalonate (diphospho) decarboxylase 0.0328993
MYO1E myosin IE 0.0325976
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.0315549
IARS1 isoleucyl-tRNA synthetase 1 0.0308949
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.0303869
LOC112694756 uncharaterized LOC112694756 0.0302806
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.030161
LMNA lamin A/C 0.0299931
NAV2 neuron navigator 2 0.0295745
ATRNL1 attractin-like 1 0.0295267
DAAM1 dishevelled associated activator of morphogenesis 1 0.0294112
MYH9 myosin, heavy chain 9, non-muscle 0.0292471
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.0288226
UBE2H ubiquitin-conjugating enzyme E2H 0.0288129
IRS1 insulin receptor substrate 1 0.0287793
EEIG2 EEIG family member 2 0.0287459
FERMT2 fermitin family member 2 0.0285103
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.028503
ABHD2 abhydrolase domain containing 2 0.0284363
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.0284311
PRSS23 protease, serine, 23 0.0283243
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.028307
PGCKA1 PDCD10 and GCKIII kinases associated 1 0.0279631
COL5A1 collagen, type V, alpha 1 0.0278192
MYO16 myosin XVI 0.0277624
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.027719
CSDE1 cold shock domain containing E1, RNA-binding 0.0273959
ETFA electron-transfer-flavoprotein, alpha polypeptide 0.0273768
RAB10 RAB10, member RAS oncogene family 0.0269096
MB21D2 Mab-21 domain containing 2 0.0267572
ERBB4 erb-b2 receptor tyrosine kinase 4 0.0267141
STARD13 StAR-related lipid transfer (START) domain containing 13 0.0266744
FGD4 FYVE, RhoGEF and PH domain containing 4 0.0266486
PBX1 pre-B-cell leukemia homeobox 1 0.0265596
SREBF2 sterol regulatory element binding transcription factor 2 0.0263733
AREG amphiregulin 0.0263395
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0262781
IDI1 isopentenyl-diphosphate delta isomerase 1 0.0258936
ZNF217 zinc finger protein 217 0.0257589
INSR insulin receptor 0.0256311
KLF6 Kruppel-like factor 6 0.0255555
HMCN1 hemicentin 1 0.0254353
LMBR1 limb development membrane protein 1 0.025115
SPPL2A signal peptide peptidase like 2A 0.0250302
TPM1 tropomyosin 1 (alpha) 0.0248665
ELP2 elongator acetyltransferase complex subunit 2 0.0247384
DLG5 discs, large homolog 5 (Drosophila) 0.0246217
EEIG1 estrogen-induced osteoclastogenesis regulator 1 0.0244511
CAPN8 calpain 8 0.0241096
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein 0.0237886
JMJD1C jumonji domain containing 1C 0.023608
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.0235482
FOXO3 forkhead box O3 0.0235354
NT5DC3 5'-nucleotidase domain containing 3 0.0233689
RHPN2 rhophilin, Rho GTPase binding protein 2 0.0233043
KLHL24 kelch-like family member 24 0.0232855
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.0231268
SDK1 sidekick cell adhesion molecule 1 0.0231066
C14ORF132 chromosome 14 open reading frame 132 0.0230889
MGLL monoglyceride lipase 0.0228858
IER3 immediate early response 3 0.0227946
TENM3 teneurin transmembrane protein 3 0.0226791
APOLD1 apolipoprotein L domain containing 1 0.0225844
ACACA acetyl-CoA carboxylase alpha 0.0223844
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0222978
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0221854
MLXIP MLX interacting protein 0.02198
NUMB numb homolog (Drosophila) 0.021895
PSD3 pleckstrin and Sec7 domain containing 3 0.0218273
SQSTM1 sequestosome 1 0.0217119
ACTN4 actinin, alpha 4 0.0214758
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0214593
MAX MYC associated factor X 0.0214392
IQANK1 IQ motif and ankyrin repeat containing 1 0.0214271
FASN fatty acid synthase 0.0211331
RDX radixin 0.0210686
DEPTOR DEP domain containing MTOR-interacting protein 0.0210565
SENP5 SUMO1/sentrin specific peptidase 5 0.0209641
BCL2 B-cell CLL/lymphoma 2 0.0208579
NPC1 Niemann-Pick disease, type C1 0.0206506
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0205788
BMERB1 bMERB domain containing 1 0.020479
PCED1B PC-esterase domain containing 1B 0.0204534
BCAS1 breast carcinoma amplified sequence 1 0.0203988
KMT2C lysine (K)-specific methyltransferase 2C 0.0203476
CYB561 cytochrome b561 0.0203183
MAVS mitochondrial antiviral signaling protein 0.0203025
ATP9A ATPase, class II, type 9A 0.0202556
AARS1 alanyl-tRNA synthetase 1 0.0202512
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0202099
GLRA3 glycine receptor, alpha 3 0.0201896
PRKCH protein kinase C, eta 0.0201477
HOOK2 hook microtubule-tethering protein 2 0.0201467
CAV1 caveolin 1, caveolae protein, 22kDa 0.0200448
RHEB Ras homolog enriched in brain 0.0200395
XRN1 5'-3' exoribonuclease 1 0.0199985
ACSL3 acyl-CoA synthetase long-chain family member 3 0.0199132
CDYL2 chromodomain protein, Y-like 2 0.0198041
ANXA2 annexin A2 0.0197994
WDR37 WD repeat domain 37 0.0197795
CEP95 centrosomal protein 95kDa 0.0197707
RBMX RNA binding motif protein, X-linked 0.0197427
WAC WW domain containing adaptor with coiled-coil 0.0196275
GTF2IRD1 GTF2I repeat domain containing 1 0.0195429
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 0.0194893
STC2 stanniocalcin 2 0.0193679
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.019316
CLIP1 CAP-GLY domain containing linker protein 1 0.0193077
CCSER1 coiled-coil serine-rich protein 1 0.0192678
SQLE squalene epoxidase 0.019263
PRUNE2 prune homolog 2 (Drosophila) 0.0192157
OGA O-GlcNAcase 0.0191919
YBX3 Y box binding protein 3 0.0191423
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.0191331
AOPEP aminopeptidase O (putative) 0.0191311
LAMA4 laminin, alpha 4 0.0189902
JUP junction plakoglobin 0.0189827
KRTAP11-1 keratin associated protein 11-1 0.0189397
CDK13 cyclin-dependent kinase 13 0.0188495
ADARB1 adenosine deaminase, RNA-specific, B1 0.0187545
SPAG9 sperm associated antigen 9 0.018674
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.0186693
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.0186001
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.0185974
COMMD10 COMM domain containing 10 0.0185359
NRCAM neuronal cell adhesion molecule 0.0185304
AFF4 AF4/FMR2 family, member 4 0.0183247
ATXN3 ataxin 3 0.0183219
FAM107B family with sequence similarity 107, member B 0.0181667
CHLSN cholesin 0.0181303
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.0180666
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0180381
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.0179956
RNF115 ring finger protein 115 0.0179947
IRS2 insulin receptor substrate 2 0.0179274
TJP1 tight junction protein 1 0.0179219
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.0178972
PLXDC2 plexin domain containing 2 0.0178887
SYTL2 synaptotagmin-like 2 0.0178282
SYT10 synaptotagmin X 0.0177567
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 0.0176737
GOLGA2 golgin A2 0.0176353
LAMP2 lysosomal-associated membrane protein 2 0.0175533
ARHGAP21 Rho GTPase activating protein 21 0.0173383
SFTPA2 surfactant protein A2 0.0173049
CLU clusterin 0.0172568
OSGIN2 oxidative stress induced growth inhibitor family member 2 0.0171377
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.0170869
BTG1 B-cell translocation gene 1, anti-proliferative 0.0170732
KMT2A lysine (K)-specific methyltransferase 2A 0.0170714
MACC1 metastasis associated in colon cancer 1 0.0170215
MYO1B myosin IB 0.0170072
DHCR24 24-dehydrocholesterol reductase 0.0168561
UBC ubiquitin C 0.0168501
RPL18 ribosomal protein L18 0.0168105
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 0.0167756
TSG101 tumor susceptibility 101 0.0166535
HELZ2 helicase with zinc finger 2, transcriptional coactivator 0.0166439
NUCB2 nucleobindin 2 0.0166297
WDR44 WD repeat domain 44 0.0166141
NPTN neuroplastin 0.0165878
ABHD18 abhydrolase domain containing 18 0.0165774
CD44 CD44 molecule (Indian blood group) 0.0165469
SLC38A2 solute carrier family 38, member 2 0.0165349
SHTN1 shootin 1 0.0164943
HELZ helicase with zinc finger 0.0164663
JMY junction mediating and regulatory protein, p53 cofactor 0.0163453
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 0.0163382
MYL12B myosin, light chain 12B, regulatory 0.0163157
MBNL1 muscleblind-like splicing regulator 1 0.0162978
TMPRSS4 transmembrane protease, serine 4 0.0162897
TMEM120B transmembrane protein 120B 0.0162628
AK1 adenylate kinase 1 0.0162299
ITPK1 inositol-tetrakisphosphate 1-kinase 0.0162176
PRXL2A peroxiredoxin like 2A 0.0161649
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 0.0161002
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 0.016039
TRIM56 tripartite motif containing 56 0.0160044
THBS1 thrombospondin 1 0.0159883
FDPS farnesyl diphosphate synthase 0.0159066
MACF1 microtubule-actin crosslinking factor 1 0.0158705
STRN3 striatin, calmodulin binding protein 3 0.0158566
CTSA cathepsin A 0.0158396
CADM1 cell adhesion molecule 1 0.0158324
RPS14 ribosomal protein S14 0.0157967
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.0157716
LARP4B La ribonucleoprotein domain family, member 4B 0.0157655
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.0156774
ARHGAP32 Rho GTPase activating protein 32 0.0156763
ZSWIM6 zinc finger, SWIM-type containing 6 0.0156566
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 0.0155371
PLD3 phospholipase D family, member 3 0.0155243
N4BP2L2 NEDD4 binding protein 2-like 2 0.0154878
C1QTNF6 C1q and tumor necrosis factor related protein 6 0.0154738
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.0153697
PHF3 PHD finger protein 3 0.0153202
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.0152528
INSIG1 insulin induced gene 1 0.0152518
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.0152484
CACUL1 CDK2-associated, cullin domain 1 0.0152454
RPL30 ribosomal protein L30 0.0152415
EXOC4 exocyst complex component 4 0.0151782
YARS1 tyrosyl-tRNA synthetase 1 0.0151493
ACLY ATP citrate lyase 0.0151012
IGSF1 immunoglobulin superfamily, member 1 0.0150747
ELOVL6 ELOVL fatty acid elongase 6 0.0150728
DUSP16 dual specificity phosphatase 16 0.0150715
ARID4B AT rich interactive domain 4B (RBP1-like) 0.015067
KPNA6 karyopherin alpha 6 (importin alpha 7) 0.0150441
HAGH hydroxyacylglutathione hydrolase 0.015042
TBX2 T-box 2 0.0148922
CCN5 cellular communication network factor 5 0.0148851
FBXL2 F-box and leucine-rich repeat protein 2 0.0148769
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 0.014817
ELF2 E74-like factor 2 (ets domain transcription factor) 0.014791
LPIN1 lipin 1 0.0147334
CSRP1 cysteine and glycine-rich protein 1 0.0147288
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.0147031
SLC39A10 solute carrier family 39 (zinc transporter), member 10 0.0146276
ABHD17C abhydrolase domain containing 17C 0.0146063
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0145639
SNX29 sorting nexin 29 0.0145572
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.014453
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.014433
RSRP1 arginine/serine-rich protein 1 0.0144269
CALU calumenin 0.0144014
NPC2 Niemann-Pick disease, type C2 0.01437
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 0.0143566
KLHL5 kelch-like family member 5 0.0143006
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.0142796
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 0.0142348
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 0.0142306
EIF3B eukaryotic translation initiation factor 3, subunit B 0.0142217
ACSS2 acyl-CoA synthetase short-chain family member 2 0.0141911
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.0141874
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.0141339
MEF2D myocyte enhancer factor 2D 0.0141047
SMG7 SMG7 nonsense mediated mRNA decay factor 0.0140063
GSK3B glycogen synthase kinase 3 beta 0.0139543
UBE2N ubiquitin-conjugating enzyme E2N 0.0139314
PDLIM7 PDZ and LIM domain 7 (enigma) 0.0139031
GOLM2 golgi membrane protein 2 0.0138068
SRBD1 S1 RNA binding domain 1 0.0137671
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0137645
NRDC nardilysin convertase 0.0137172
PICALM phosphatidylinositol binding clathrin assembly protein 0.0136552
RYK receptor-like tyrosine kinase 0.0135245
WDR70 WD repeat domain 70 0.0135195
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 0.0135095
USO1 USO1 vesicle transport factor 0.0134742
PTPRE protein tyrosine phosphatase, receptor type, E 0.0134327
CPEB2 cytoplasmic polyadenylation element binding protein 2 0.013425
VEZT vezatin, adherens junctions transmembrane protein 0.0133904
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) 0.0133873
TTC3 tetratricopeptide repeat domain 3 0.0133812
ACTG1 actin gamma 1 0.0133607
TEX14 testis expressed 14 0.0133256
RUSC2 RUN and SH3 domain containing 2 0.0133064
FAM13B family with sequence similarity 13, member B 0.0132944
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.0132922
RIPOR3 RIPOR family member 3 0.0132759
ANXA3 annexin A3 0.0132373
ATG10 autophagy related 10 0.013216
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 0.0131981
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 0.0131859
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.013177
MXD1 MAX dimerization protein 1 0.0131583
SRP54 signal recognition particle 54kDa 0.0131301
ARHGAP17 Rho GTPase activating protein 17 0.0130651
NR2C1 nuclear receptor subfamily 2, group C, member 1 0.0130295
PHF20 PHD finger protein 20 0.0130122
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.0130014
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.0130007
HOOK3 hook microtubule-tethering protein 3 0.0129674
NEMF nuclear export mediator factor 0.0129451
PTPN21 protein tyrosine phosphatase, non-receptor type 21 0.0128884
EMC3 ER membrane protein complex subunit 3 0.0128241
ZC3H3 zinc finger CCCH-type containing 3 0.0128193
PFKL phosphofructokinase, liver 0.0127554
TMEM192 transmembrane protein 192 0.0127478
TPM3 tropomyosin 3 0.0127303
DAPK3 death-associated protein kinase 3 0.0127129
CCSER2 coiled-coil serine-rich protein 2 0.0126605
ERCC1 excision repair cross-complementation group 1 0.0126566
UGDH UDP-glucose 6-dehydrogenase 0.0126368
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.0126247
INTS8 integrator complex subunit 8 0.0126012
AKAP9 A kinase (PRKA) anchor protein 9 0.0125998
COG5 component of oligomeric golgi complex 5 0.0125677
TLN1 talin 1 0.0125255
S100A10 S100 calcium binding protein A10 0.0125102
IER5L immediate early response 5-like 0.0125018
LTBP1 latent transforming growth factor beta binding protein 1 0.0124341
ADNP activity-dependent neuroprotector homeobox 0.012404
SIAH2 siah E3 ubiquitin protein ligase 2 0.0122883
ANAPC5 anaphase promoting complex subunit 5 0.0122531
TACC1 transforming, acidic coiled-coil containing protein 1 0.0122449
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.0122304
PHACTR4 phosphatase and actin regulator 4 0.0122042
FRS2 fibroblast growth factor receptor substrate 2 0.0121131
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 0.0121124
YPEL2 yippee-like 2 (Drosophila) 0.0120815
TNRC6B trinucleotide repeat containing 6B 0.0120725
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.0120627
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.0120562
WWC3 WWC family member 3 0.0120513
PANK3 pantothenate kinase 3 0.0120293
SPG11 spastic paraplegia 11 (autosomal recessive) 0.0120142
PKP4 plakophilin 4 0.0118995
USP43 ubiquitin specific peptidase 43 0.0118588
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.0118192
DNASE1 deoxyribonuclease I 0.0117985
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.011783
CRY1 cryptochrome circadian clock 1 0.0117569
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 0.0117435
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0116938
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit 0.0116918
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 0.0116903
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 0.0116673
DOP1B DOP1 leucine zipper like protein B 0.0116567
RPS2 ribosomal protein S2 0.0116409
RECQL5 RecQ protein-like 5 0.011634
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.0116266
ZNF804B zinc finger protein 804B 0.0116191
TARBP1 TAR (HIV-1) RNA binding protein 1 0.0116112
PRKCA protein kinase C, alpha 0.0115992
SETD1B SET domain containing 1B 0.0115842
GINM1 glycoprotein integral membrane 1 0.0115765
SGPP1 sphingosine-1-phosphate phosphatase 1 0.0115506
PDLIM5 PDZ and LIM domain 5 0.011539
RPL35A ribosomal protein L35a 0.0114661
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0114609
EZR ezrin 0.0114499
MARK4 MAP/microtubule affinity-regulating kinase 4 0.0114408
DUSP4 dual specificity phosphatase 4 0.0114308
LRPPRC leucine-rich pentatricopeptide repeat containing 0.0114249
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 0.0114187
ZBTB25 zinc finger and BTB domain containing 25 0.0114051
RPS21 ribosomal protein S21 0.0113941
JAK1 Janus kinase 1 0.0113301
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0113195
RPS16 ribosomal protein S16 0.0112772
STX5 syntaxin 5 0.0112577
TMOD3 tropomodulin 3 (ubiquitous) 0.0112289
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.0112027
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) 0.0111961
POU2F1 POU class 2 homeobox 1 0.0111665
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 0.011143
USP36 ubiquitin specific peptidase 36 0.0111374
DPH6 diphthamine biosynthesis 6 0.0111299
RNF185 ring finger protein 185 0.0111298
DOCK1 dedicator of cytokinesis 1 0.0111016
JADE2 jade family PHD finger 2 0.0110959
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.0110829
CAMKMT calmodulin-lysine N-methyltransferase 0.0110731
PPL periplakin 0.0110625
RETREG3 reticulophagy regulator family member 3 0.0110446
TTC1 tetratricopeptide repeat domain 1 0.0110296
ANKRD17 ankyrin repeat domain 17 0.0110289
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.0110264
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.0110207
TSPAN15 tetraspanin 15 0.0110173
ISG20 interferon stimulated exonuclease gene 20kDa 0.0110135
IGBP1 immunoglobulin (CD79A) binding protein 1 0.0109917
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.0109889
JUN jun proto-oncogene 0.0109837
NPNT nephronectin 0.010978
LGALS3 lectin, galactoside-binding, soluble, 3 0.010964
YME1L1 YME1-like 1 ATPase 0.0109424
RAB1A RAB1A, member RAS oncogene family 0.0109285
NR2C2 nuclear receptor subfamily 2, group C, member 2 0.0109241
SENP6 SUMO1/sentrin specific peptidase 6 0.0109209
TCF12 transcription factor 12 0.0109194
DNAAF2 dynein, axonemal, assembly factor 2 0.0109015
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 0.0108938
PRPF38B pre-mRNA processing factor 38B 0.0108882
RPL12 ribosomal protein L12 0.010847
ATG2B autophagy related 2B 0.0108158
MSMO1 methylsterol monooxygenase 1 0.0107781
IDS iduronate 2-sulfatase 0.0107698
ARID4A AT rich interactive domain 4A (RBP1-like) 0.0107684
HMGXB3 HMG box domain containing 3 0.010753
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.0107228
TSPAN12 tetraspanin 12 0.0107031
GOLGA8B golgin A8 family, member B 0.0107013
TPT1 tumor protein, translationally-controlled 1 0.0106974
SCAF11 SR-related CTD-associated factor 11 0.010669
ALMS1 Alstrom syndrome protein 1 0.0106554
NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 0.0106502
CAB39 calcium binding protein 39 0.0106436
PITPNB phosphatidylinositol transfer protein, beta 0.0106243
BICDL1 BICD family like cargo adaptor 1 0.0106049
UBE2B ubiquitin-conjugating enzyme E2B 0.0105954
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.01059
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.0105828
RANGAP1 Ran GTPase activating protein 1 0.0105661
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.0105605
WASF2 WAS protein family, member 2 0.0105525
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 0.0105411
RASEF RAS and EF-hand domain containing 0.0105315
LMCD1 LIM and cysteine-rich domains 1 0.0105303
SOCS4 suppressor of cytokine signaling 4 0.0105006
S100A14 S100 calcium binding protein A14 0.0104361
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.0104154
TAOK3 TAO kinase 3 0.0104108
FNIP1 folliculin interacting protein 1 0.0103876
SND1 staphylococcal nuclease and tudor domain containing 1 0.0103807
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.0103744
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.0103739
TUG1 taurine up-regulated 1 (non-protein coding) 0.0103707
MARK2 MAP/microtubule affinity-regulating kinase 2 0.0103678
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0103676
RNF149 ring finger protein 149 0.0103522
TAGLN2 transgelin 2 0.0103269
TXNRD1 thioredoxin reductase 1 0.0103248
WSB1 WD repeat and SOCS box containing 1 0.0103206
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.0102962
UBTD1 ubiquitin domain containing 1 0.0102784
PACS1 phosphofurin acidic cluster sorting protein 1 0.0102653
UBE3C ubiquitin protein ligase E3C 0.0102471
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 0.0102471
C6ORF89 chromosome 6 open reading frame 89 0.0102453
DENND5B DENN/MADD domain containing 5B 0.0102356
STARD10 StAR-related lipid transfer (START) domain containing 10 0.010227
FTL ferritin, light polypeptide 0.0102149
RSBN1 round spermatid basic protein 1 0.0102102
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.0101904
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 0.0101628
TRIM26 tripartite motif containing 26 0.0101579
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 0.0101529
KANTR KDM5C adjacent non-coding transcript 0.0101331
CHPF chondroitin polymerizing factor 0.0100998
EFL1 elongation factor like GTPase 1 0.0100982
NBPF15 neuroblastoma breakpoint family, member 15 0.0100911
ZNF516 zinc finger protein 516 0.0100876

decreased expression

Symbol Name Standardized Value
WWOX WW domain containing oxidoreductase -0.180792
SULF2 sulfatase 2 -0.156996
KRT8 keratin 8, type II -0.155676
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.12165
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.115973
KRT19 keratin 19, type I -0.109854
GFRA1 GDNF family receptor alpha 1 -0.109051
EMP2 epithelial membrane protein 2 -0.105931
KRT18 keratin 18, type I -0.105569
ESR1 estrogen receptor 1 -0.101225
AGR2 anterior gradient 2 -0.0899962
GRHL2 grainyhead-like 2 (Drosophila) -0.0855281
JARID2 jumonji, AT rich interactive domain 2 -0.0832585
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0799136
TMEM64 transmembrane protein 64 -0.0770941
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 -0.0734504
PKM pyruvate kinase, muscle -0.0641147
NCOA3 nuclear receptor coactivator 3 -0.0586703
SMYD3 SET and MYND domain containing 3 -0.0546693
ZMYND8 zinc finger, MYND-type containing 8 -0.0545077
PARD3 par-3 family cell polarity regulator -0.053344
ATAD2 ATPase family, AAA domain containing 2 -0.0525149
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.0519566
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0516258
CA12 carbonic anhydrase XII -0.0511591
CALR calreticulin -0.0505552
ENO1 enolase 1, (alpha) -0.0499306
BIRC6 baculoviral IAP repeat containing 6 -0.0488673
MACROD2 MACRO domain containing 2 -0.046821
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -0.0464414
CENPP centromere protein P -0.0456431
MKI67 marker of proliferation Ki-67 -0.0455338
RPL37A ribosomal protein L37a -0.0447011
CTNND2 catenin (cadherin-associated protein), delta 2 -0.0446078
IFI6 interferon, alpha-inducible protein 6 -0.0445018
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0441578
GSE1 Gse1 coiled-coil protein -0.0439952
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0422923
PPP1R13B protein phosphatase 1, regulatory subunit 13B -0.0418631
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0409662
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.0404636
KAT6B K(lysine) acetyltransferase 6B -0.0388389
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.038778
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.0378692
GNA14 guanine nucleotide binding protein (G protein), alpha 14 -0.0371104
RAB31 RAB31, member RAS oncogene family -0.0370216
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0364279
TRERF1 transcriptional regulating factor 1 -0.0363641
MAST4 microtubule associated serine/threonine kinase family member 4 -0.0363088
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0362728
USP34 ubiquitin specific peptidase 34 -0.0362515
TNRC18 trinucleotide repeat containing 18 -0.036135
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.0361293
LRP1B low density lipoprotein receptor-related protein 1B -0.0357045
SKA2 spindle and kinetochore associated complex subunit 2 -0.0351495
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.0346978
TMCC1 transmembrane and coiled-coil domain family 1 -0.0345604
XBP1 X-box binding protein 1 -0.0341103
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) -0.0340384
SMIM44 small integral membrane protein 44 -0.0339844
SACK1B scaffolding CK1 anchoring protein B -0.0338725
RNF24 ring finger protein 24 -0.0337436
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -0.0336156
C1ORF21 chromosome 1 open reading frame 21 -0.0335221
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -0.0334096
GNAS GNAS complex locus -0.0333609
HMGB1 high mobility group box 1 -0.0332365
KYNU kynureninase -0.0324349
BMP7 bone morphogenetic protein 7 -0.0322805
RAD51B RAD51 paralog B -0.0321412
FANCA Fanconi anemia, complementation group A -0.0317868
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0317257
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0316587
RCOR1 REST corepressor 1 -0.0310767
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 -0.0308459
ADCY1 adenylate cyclase 1 (brain) -0.0305442
USP32 ubiquitin specific peptidase 32 -0.0302505
RERE arginine-glutamic acid dipeptide (RE) repeats -0.0301655
NCOA2 nuclear receptor coactivator 2 -0.0296132
R3HDM2 R3H domain containing 2 -0.0294983
NF1 neurofibromin 1 -0.0287788
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) -0.0286497
CPA6 carboxypeptidase A6 -0.0279281
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.0278074
SMG6 SMG6 nonsense mediated mRNA decay factor -0.0276977
ZNF609 zinc finger protein 609 -0.0271009
SETD5 SET domain containing 5 -0.0270036
SRPK2 SRSF protein kinase 2 -0.0266841
MAML3 mastermind-like 3 (Drosophila) -0.0262914
ZFAND3 zinc finger, AN1-type domain 3 -0.0261723
CCND1 cyclin D1 -0.0261583
CST3 cystatin C -0.0259572
FANCC Fanconi anemia, complementation group C -0.0259041
BRCA2 breast cancer 2, early onset -0.0257297
RBPMS RNA binding protein with multiple splicing -0.0256976
PRKCE protein kinase C, epsilon -0.0256533
BAZ1B bromodomain adjacent to zinc finger domain, 1B -0.0255747
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.0253366
SUMO2 small ubiquitin-like modifier 2 -0.0251277
SPIDR scaffolding protein involved in DNA repair -0.0250942
PDE7A phosphodiesterase 7A -0.0250731
MTDH metadherin -0.0248503
BRI3BP BRI3 binding protein -0.0246937
POLK polymerase (DNA directed) kappa -0.0245172
NR6A1 nuclear receptor subfamily 6, group A, member 1 -0.0242507
ANKRD11 ankyrin repeat domain 11 -0.0241908
SCAI suppressor of cancer cell invasion -0.0241415
TOM1L2 target of myb1-like 2 (chicken) -0.0241411
ATP5F1E ATP synthase F1 subunit epsilon -0.0241338
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.023861
SIDT1 SID1 transmembrane family, member 1 -0.0237252
DSPP dentin sialophosphoprotein -0.0236073
ADIPOR2 adiponectin receptor 2 -0.023581
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0235661
GPC6 glypican 6 -0.0232621
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.0232037
FAF1 Fas (TNFRSF6) associated factor 1 -0.0230191
TPD52L1 tumor protein D52-like 1 -0.0229966
RNASE3 ribonuclease, RNase A family, 3 -0.0229679
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0228934
RPS3 ribosomal protein S3 -0.0228411
SIN3A SIN3 transcription regulator family member A -0.0227619
NEBL nebulette -0.0226606
GNPDA1 glucosamine-6-phosphate deaminase 1 -0.0224761
SIL1 SIL1 nucleotide exchange factor -0.0224625
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.0223905
HDGFL3 HDGF like 3 -0.0221908
CLTC clathrin, heavy chain (Hc) -0.0221792
BPTF bromodomain PHD finger transcription factor -0.022152
NHSL1 NHS-like 1 -0.0218861
TIAM1 T-cell lymphoma invasion and metastasis 1 -0.0218003
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B -0.0217889
HACD2 3-hydroxyacyl-CoA dehydratase 2 -0.021785
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -0.0217218
FANCI Fanconi anemia, complementation group I -0.0217186
KIF13A kinesin family member 13A -0.0217161
CELF1 CUGBP, Elav-like family member 1 -0.0216384
DGKH diacylglycerol kinase, eta -0.0215859
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -0.0215801
TPX2 TPX2, microtubule-associated -0.0215787
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 -0.0213826
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -0.02134
PPP6R2 protein phosphatase 6, regulatory subunit 2 -0.021292
CHD4 chromodomain helicase DNA binding protein 4 -0.0212919
FREM2 FRAS1 related extracellular matrix protein 2 -0.0212099
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 -0.0212037
KTN1 kinectin 1 (kinesin receptor) -0.0211236
CDV3 CDV3 homolog (mouse) -0.0210476
LY6E lymphocyte antigen 6 complex, locus E -0.0210302
SPATS2 spermatogenesis associated, serine-rich 2 -0.0209208
FOXP1 forkhead box P1 -0.0207218
RBL1 retinoblastoma-like 1 -0.020523
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -0.0203749
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 -0.0202988
RPS6 ribosomal protein S6 -0.0202483
MAN1A2 mannosidase, alpha, class 1A, member 2 -0.0202363
KRIT1 KRIT1, ankyrin repeat containing -0.0202013
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.020113
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0200342
NRIP1 nuclear receptor interacting protein 1 -0.019894
MED12L mediator complex subunit 12-like -0.0198776
SHANK2 SH3 and multiple ankyrin repeat domains 2 -0.0197629
SSH2 slingshot protein phosphatase 2 -0.0197153
KDM2A lysine (K)-specific demethylase 2A -0.0196556
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.019625
FAM120A family with sequence similarity 120A -0.0195725
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.0195229
RPS17 ribosomal protein S17 -0.0195181
NUP214 nucleoporin 214kDa -0.0195161
SERF2 small EDRK-rich factor 2 -0.0194889
ITGB4 integrin, beta 4 -0.0193775
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0193704
RABEP1 rabaptin, RAB GTPase binding effector protein 1 -0.0193377
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.0193124
STXBP4 syntaxin binding protein 4 -0.019297
NOP58 NOP58 ribonucleoprotein -0.0192716
DNPEP aspartyl aminopeptidase -0.0190812
EHBP1 EH domain binding protein 1 -0.0188136
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -0.0188131
NPAS3 neuronal PAS domain protein 3 -0.0186331
HIP1 huntingtin interacting protein 1 -0.018526
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0184817
CAPZB capping protein (actin filament) muscle Z-line, beta -0.0184533
PTPRF protein tyrosine phosphatase, receptor type, F -0.0184523
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -0.0184337
HDLBP high density lipoprotein binding protein -0.018417
ARID1A AT rich interactive domain 1A (SWI-like) -0.018347
EPHA4 EPH receptor A4 -0.0182694
MCU mitochondrial calcium uniporter -0.0182117
AMZ1 archaelysin family metallopeptidase 1 -0.0181809
RANBP17 RAN binding protein 17 -0.0180547
RPL35 ribosomal protein L35 -0.0180226
TRIO trio Rho guanine nucleotide exchange factor -0.0179504
WDHD1 WD repeat and HMG-box DNA binding protein 1 -0.0179275
PRIM2 primase, DNA, polypeptide 2 (58kDa) -0.0179137
SHISA9 shisa family member 9 -0.0178142
CLASP1 cytoplasmic linker associated protein 1 -0.0177494
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 -0.0176269
STIP1 stress-induced phosphoprotein 1 -0.0176212
TMSB10 thymosin beta 10 -0.0176151
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 -0.017598
HNRNPR heterogeneous nuclear ribonucleoprotein R -0.0175408
HDAC8 histone deacetylase 8 -0.0175337
DNM2 dynamin 2 -0.0175301
RAB3D RAB3D, member RAS oncogene family -0.0174934
EPHA6 EPH receptor A6 -0.0174927
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.017486
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.0174512
PLXNA4 plexin A4 -0.0174412
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) -0.0174095
NUCB1 nucleobindin 1 -0.0174021
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0173989
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 -0.0173013
PHF14 PHD finger protein 14 -0.0172727
RSF1 remodeling and spacing factor 1 -0.0172567
WDR33 WD repeat domain 33 -0.0172557
TTF2 transcription termination factor, RNA polymerase II -0.0172291
NSD2 nuclear receptor binding SET domain protein 2 -0.0171844
CNKSR3 CNKSR family member 3 -0.0171744
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.0171599
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -0.0171417
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -0.0171336
OLA1 Obg-like ATPase 1 -0.0170784
RPL6 ribosomal protein L6 -0.0170716
COPE coatomer protein complex, subunit epsilon -0.0169911
MRTFA myocardin related transcription factor A -0.0169254
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 -0.0169216
EEA1 early endosome antigen 1 -0.0168771
CNOT10 CCR4-NOT transcription complex, subunit 10 -0.0168569
MCM4 minichromosome maintenance complex component 4 -0.0168558
KCMF1 potassium channel modulatory factor 1 -0.0168008
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -0.0167628
IFITM3 interferon induced transmembrane protein 3 -0.0167519
MBD5 methyl-CpG binding domain protein 5 -0.0166567
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like -0.016639
RAD21 RAD21 homolog (S. pombe) -0.0166125
NECAB1 N-terminal EF-hand calcium binding protein 1 -0.0165754
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0165738
SON SON DNA binding protein -0.016558
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa -0.0165243
FOXK2 forkhead box K2 -0.0164745
GMDS GDP-mannose 4,6-dehydratase -0.0164205
AGO2 argonaute RISC catalytic component 2 -0.016408
DPP8 dipeptidyl-peptidase 8 -0.0163599
BSG basigin (Ok blood group) -0.0163299
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) -0.0163021
RNGTT RNA guanylyltransferase and 5'-phosphatase -0.0162322
TET2 tet methylcytosine dioxygenase 2 -0.016205
RPLP1 ribosomal protein, large, P1 -0.0161755
CBX3 chromobox homolog 3 -0.0161362
TUBA1B tubulin, alpha 1b -0.0161325
DTNB dystrobrevin, beta -0.0161047
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -0.0160507
TNK2 tyrosine kinase, non-receptor, 2 -0.0159777
CD63 CD63 molecule -0.0159652
CCNI cyclin I -0.0159473
VWA8 von Willebrand factor A domain containing 8 -0.0158802
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 -0.0158794
KPNB1 karyopherin (importin) beta 1 -0.0158756
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -0.0156875
TGOLN2 trans-golgi network protein 2 -0.015658
NUP160 nucleoporin 160kDa -0.0155996
MINK1 misshapen-like kinase 1 -0.015577
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -0.015504
PIGU phosphatidylinositol glycan anchor biosynthesis, class U -0.015471
METTL16 methyltransferase like 16 -0.0154048
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0153851
RCC2 regulator of chromosome condensation 2 -0.0153843
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -0.0153796
PFN1 profilin 1 -0.0153345
LATS1 large tumor suppressor kinase 1 -0.0153284
ESRP1 epithelial splicing regulatory protein 1 -0.015327
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -0.0152871
ZRANB3 zinc finger, RAN-binding domain containing 3 -0.0152772
PTBP3 polypyrimidine tract binding protein 3 -0.0152334
BRCA1 breast cancer 1, early onset -0.0152319
POM121C POM121 transmembrane nucleoporin C -0.0152243
TRIP11 thyroid hormone receptor interactor 11 -0.0151583
RAB30 RAB30, member RAS oncogene family -0.0151262
RXRA retinoid X receptor, alpha -0.0151147
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) -0.0150687
NUMA1 nuclear mitotic apparatus protein 1 -0.0150515
KAZN kazrin, periplakin interacting protein -0.0150347
RTN4 reticulon 4 -0.0150259
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0150155
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -0.0150131
MECOM MDS1 and EVI1 complex locus -0.0150117
SET SET nuclear proto-oncogene -0.0149817
IFI27 interferon, alpha-inducible protein 27 -0.0149577
TOP6BL TOP6B like initiator of meiotic double strand breaks -0.0149433
UBE2K ubiquitin-conjugating enzyme E2K -0.014881
DLG1 discs, large homolog 1 (Drosophila) -0.0148582
NUP155 nucleoporin 155kDa -0.014843
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -0.0148372
MZT2B mitotic spindle organizing protein 2B -0.0148262
TUFM Tu translation elongation factor, mitochondrial -0.0147973
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.0147243
MON2 MON2 homolog (S. cerevisiae) -0.0147184
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -0.0147032
SP3 Sp3 transcription factor -0.0146967
CAPN7 calpain 7 -0.0146787
RTN4RL1 reticulon 4 receptor-like 1 -0.0146764
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.0146721
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0146615
GPATCH8 G patch domain containing 8 -0.0146466
KANK2 KN motif and ankyrin repeat domains 2 -0.0145833
CASP8AP2 caspase 8 associated protein 2 -0.0145708
STIL SCL/TAL1 interrupting locus -0.0145622
MTSS1 metastasis suppressor 1 -0.014557
SCLT1 sodium channel and clathrin linker 1 -0.0145492
TRIP12 thyroid hormone receptor interactor 12 -0.0145389
LAPTM4B lysosomal protein transmembrane 4 beta -0.0145013
CDK5RAP2 CDK5 regulatory subunit associated protein 2 -0.0144977
CCAR1 cell division cycle and apoptosis regulator 1 -0.0144884
CHD8 chromodomain helicase DNA binding protein 8 -0.0144407
TMPO thymopoietin -0.0144181
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.0144169
RPS10 ribosomal protein S10 -0.0144108
POLE polymerase (DNA directed), epsilon, catalytic subunit -0.0143941
SAP130 Sin3A-associated protein, 130kDa -0.0143674
TMBIM4 transmembrane BAX inhibitor motif containing 4 -0.0143564
TUBB tubulin, beta class I -0.0142926
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -0.01428
PLEKHA7 pleckstrin homology domain containing, family A member 7 -0.014213
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.0141954
FBXO34 F-box protein 34 -0.0141888
MTA3 metastasis associated 1 family, member 3 -0.0141367
FCHSD2 FCH and double SH3 domains 2 -0.0141345
NRG3 neuregulin 3 -0.0141063
OSBPL10 oxysterol binding protein-like 10 -0.0141002
SPNS1 spinster homolog 1 (Drosophila) -0.0140904
UBAP2L ubiquitin associated protein 2-like -0.0140848
RPS7 ribosomal protein S7 -0.0140478
HSPB1 heat shock 27kDa protein 1 -0.0140444
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -0.0140375
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0139674
ENOSF1 enolase superfamily member 1 -0.0139584
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) -0.0139483
SASH1 SAM and SH3 domain containing 1 -0.0139411
THRB thyroid hormone receptor, beta -0.0139286
LDHA lactate dehydrogenase A -0.0138598
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) -0.0138166
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 -0.0138136
WWC1 WW and C2 domain containing 1 -0.013708
MPG N-methylpurine-DNA glycosylase -0.0136938
ZER1 zyg-11 related, cell cycle regulator -0.0136357
PDIA4 protein disulfide isomerase family A, member 4 -0.013634
EEF2K eukaryotic elongation factor 2 kinase -0.0136237
RERG RAS-like, estrogen-regulated, growth inhibitor -0.0136171
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -0.0136148
ITPRID2 ITPR interacting domain containing 2 -0.0135965
PIGM phosphatidylinositol glycan anchor biosynthesis, class M -0.0135452
WDR59 WD repeat domain 59 -0.0135355
EDF1 endothelial differentiation-related factor 1 -0.0135233
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 -0.0134951
USP15 ubiquitin specific peptidase 15 -0.0134192
SEPTIN9 septin 9 -0.0134027
TPI1 triosephosphate isomerase 1 -0.0134003
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.0133935
MTMR12 myotubularin related protein 12 -0.0133537
SEC11A SEC11 homolog A (S. cerevisiae) -0.0133184
MLEC malectin -0.0133181
TMED8 transmembrane emp24 protein transport domain containing 8 -0.0132988
ADI1 acireductone dioxygenase 1 -0.0132936
BLM Bloom syndrome, RecQ helicase-like -0.0132899
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E -0.0132393
SLC16A6 solute carrier family 16, member 6 -0.0132347
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -0.0132208
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) -0.0131841
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 -0.0131825
CTTN cortactin -0.013171
SUCO SUN domain containing ossification factor -0.0131519
ARL3 ADP-ribosylation factor-like 3 -0.0131254
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 -0.0130837
DTD1 D-tyrosyl-tRNA deacylase 1 -0.013044
MYO5C myosin VC -0.013018
LPP LIM domain containing preferred translocation partner in lipoma -0.0130025
PRR11 proline rich 11 -0.0129415
TTC28 tetratricopeptide repeat domain 28 -0.0129392
C19ORF53 chromosome 19 open reading frame 53 -0.0129216
BTBD7 BTB (POZ) domain containing 7 -0.0128561
RPS11 ribosomal protein S11 -0.0127798
ZFR zinc finger RNA binding protein -0.0127648
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.0127628
SNX4 sorting nexin 4 -0.0127593
FBP1 fructose-1,6-bisphosphatase 1 -0.012757
TBC1D2B TBC1 domain family, member 2B -0.0127506
CORO1B coronin, actin binding protein, 1B -0.0127494
THOC2 THO complex 2 -0.0127212
NOL10 nucleolar protein 10 -0.0127064
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.0126622
NPEPPS aminopeptidase puromycin sensitive -0.0126621
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) -0.0126495
ZFP64 ZFP64 zinc finger protein -0.0126466
RRP1B ribosomal RNA processing 1B -0.0126314
KATNBL1 katanin p80 subunit B-like 1 -0.012619
MRPL41 mitochondrial ribosomal protein L41 -0.0126144
SF3B3 splicing factor 3b, subunit 3, 130kDa -0.0126142
GDI2 GDP dissociation inhibitor 2 -0.0125925
GNA12 guanine nucleotide binding protein (G protein) alpha 12 -0.0125645
SMC5 structural maintenance of chromosomes 5 -0.0125014
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.0124986
FAM168A family with sequence similarity 168, member A -0.012465
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -0.0124566
MARCHF7 membrane associated ring-CH-type finger 7 -0.012421
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -0.0124198
CDK19 cyclin-dependent kinase 19 -0.0124197
FUBP3 far upstream element (FUSE) binding protein 3 -0.0124008
GATAD2A GATA zinc finger domain containing 2A -0.0123921
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C -0.0123872
CDK6 cyclin-dependent kinase 6 -0.0123673
STARD7 StAR-related lipid transfer (START) domain containing 7 -0.0123576
RNF168 ring finger protein 168, E3 ubiquitin protein ligase -0.0123494
AQR aquarius intron-binding spliceosomal factor -0.0123316
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -0.0122888
MAPK9 mitogen-activated protein kinase 9 -0.0122635
CEP128 centrosomal protein 128kDa -0.0122461
PTGES2 prostaglandin E synthase 2 -0.0122457
SUFU suppressor of fused homolog (Drosophila) -0.0122363
DPP3 dipeptidyl-peptidase 3 -0.0122112
PCM1 pericentriolar material 1 -0.0122053
FBXL17 F-box and leucine-rich repeat protein 17 -0.0121972
RC3H1 ring finger and CCCH-type domains 1 -0.012187
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -0.0121862
DHFR dihydrofolate reductase -0.0121747
COG6 component of oligomeric golgi complex 6 -0.0121623
KIF5B kinesin family member 5B -0.0121311
NHP2 NHP2 ribonucleoprotein -0.0121269
CLSTN1 calsyntenin 1 -0.0120894
RNF169 ring finger protein 169 -0.0120735
RPS29 ribosomal protein S29 -0.0120633
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum) -0.0120615
MAP4 microtubule-associated protein 4 -0.0120553
HELLS helicase, lymphoid-specific -0.0120356
ADGRL1 adhesion G protein-coupled receptor L1 -0.012035
AP2S1 adaptor-related protein complex 2, sigma 1 subunit -0.0120054
TAC4 tachykinin 4 (hemokinin) -0.0120049
SYPL1 synaptophysin-like 1 -0.0120011
SCFD2 sec1 family domain containing 2 -0.011992
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.0119712
MICU1 mitochondrial calcium uptake 1 -0.0119411
TUBB4B tubulin, beta 4B class IVb -0.0119021
RAB11FIP3 RAB11 family interacting protein 3 (class II) -0.0118453
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -0.0118429
SLC35E2B solute carrier family 35, member E2B -0.0118422
DARS1 aspartyl-tRNA synthetase 1 -0.0118343
ARHGAP10 Rho GTPase activating protein 10 -0.0118326
ZHX2 zinc fingers and homeoboxes 2 -0.0118175
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -0.0118114
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 -0.0118002
TMC4 transmembrane channel-like 4 -0.0117877
TEX2 testis expressed 2 -0.0117683
PARK7 parkinson protein 7 -0.0117449
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) -0.0117089
SCN8A sodium channel, voltage gated, type VIII alpha subunit -0.0117059
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -0.011686
SHROOM2 shroom family member 2 -0.0116718
FTH1 ferritin, heavy polypeptide 1 -0.0116593
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2 -0.0116185
MCM10 minichromosome maintenance complex component 10 -0.0115724
TOPBP1 topoisomerase (DNA) II binding protein 1 -0.0115576
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa -0.0115343
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -0.0115322
DCPH1 damage control phosphatase 1 -0.0114928
DNAAF5 dynein, axonemal, assembly factor 5 -0.0114694
RFWD3 ring finger and WD repeat domain 3 -0.0114607
CD164 CD164 molecule, sialomucin -0.011443
CGGBP1 CGG triplet repeat binding protein 1 -0.011423
BICRAL BICRA like chromatin remodeling complex associated protein -0.0114059
MYO1D myosin ID -0.0113966
WDR82 WD repeat domain 82 -0.0113836
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -0.0113715
SUSD4 sushi domain containing 4 -0.011359
PRRT3 proline-rich transmembrane protein 3 -0.0113561
ARSG arylsulfatase G -0.0113333
FOXRED2 FAD-dependent oxidoreductase domain containing 2 -0.011333
RBM26 RNA binding motif protein 26 -0.0113227
RBBP4 retinoblastoma binding protein 4 -0.0113188
GTF2I general transcription factor IIi -0.0113156
REEP5 receptor accessory protein 5 -0.0113041
CAMK2G calcium/calmodulin-dependent protein kinase II gamma -0.0113009
ARHGAP11B Rho GTPase activating protein 11B -0.0112928
TMEM245 transmembrane protein 245 -0.011292
ADCY9 adenylate cyclase 9 -0.0112818
PHIP pleckstrin homology domain interacting protein -0.0112662
SKIC3 SKI3 subunit of superkiller complex -0.0112556
MCM7 minichromosome maintenance complex component 7 -0.0112307
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha -0.0112173
UBE4A ubiquitination factor E4A -0.0112106
NCOR1 nuclear receptor corepressor 1 -0.0111994
CBX5 chromobox homolog 5 -0.0111772
ECE1 endothelin converting enzyme 1 -0.0111651
ZNRF3 zinc and ring finger 3 -0.0111605
CFAP44 cilia and flagella associated protein 44 -0.0111375
CNBP CCHC-type zinc finger, nucleic acid binding protein -0.0111339
CANX calnexin -0.0111333
EPS15 epidermal growth factor receptor pathway substrate 15 -0.0111078
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.0110955
CDC27 cell division cycle 27 -0.0110857
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) -0.0110792