MCF7_SGI-1776 free base_10nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description SGI-1776 free base 10nM perturbation in MCF7 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the MCF7_SGI-1776 free base_10nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
PARD6B par-6 family cell polarity regulator beta 0.167087
BCAS3 breast carcinoma amplified sequence 3 0.156908
ESR1 estrogen receptor 1 0.117383
VMP1 vacuole membrane protein 1 0.0947416
TPM4 tropomyosin 4 0.0926913
SULF2 sulfatase 2 0.0907935
GATA3 GATA binding protein 3 0.090675
NCOA3 nuclear receptor coactivator 3 0.0862432
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.084044
DSPP dentin sialophosphoprotein 0.0810047
THSD4 thrombospondin, type I, domain containing 4 0.0779473
GRHL2 grainyhead-like 2 (Drosophila) 0.0770686
UGDH UDP-glucose 6-dehydrogenase 0.0697152
ERBB4 erb-b2 receptor tyrosine kinase 4 0.0694987
EMP2 epithelial membrane protein 2 0.0667044
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0650006
MACROD2 MACRO domain containing 2 0.0607421
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.0592343
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 0.0589631
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.057519
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0572495
NCAM2 neural cell adhesion molecule 2 0.0551303
TRIM37 tripartite motif containing 37 0.0542322
STARD13 StAR-related lipid transfer (START) domain containing 13 0.0527106
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.0495268
PACS1 phosphofurin acidic cluster sorting protein 1 0.0495248
NRCAM neuronal cell adhesion molecule 0.0471332
GSK3B glycogen synthase kinase 3 beta 0.0462325
ADIPOR2 adiponectin receptor 2 0.0419787
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.0411251
RGS6 regulator of G-protein signaling 6 0.0402505
MYO5C myosin VC 0.0399026
VCL vinculin 0.0393502
AKAP9 A kinase (PRKA) anchor protein 9 0.0391943
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.0372877
TUBD1 tubulin, delta 1 0.0364323
KRT19 keratin 19, type I 0.035902
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.0349575
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.0346294
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 0.0344835
CREBBP CREB binding protein 0.0340965
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0339646
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) 0.0337284
NRG3 neuregulin 3 0.0334407
ITPRID2 ITPR interacting domain containing 2 0.0333257
KTN1 kinectin 1 (kinesin receptor) 0.0331065
RGS17 regulator of G-protein signaling 17 0.0320437
IFI6 interferon, alpha-inducible protein 6 0.0318435
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.031415
EEIG1 estrogen-induced osteoclastogenesis regulator 1 0.0313051
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.0312169
ATXN7L1 ataxin 7-like 1 0.0311336
IGFBP5 insulin-like growth factor binding protein 5 0.0307421
MLPH melanophilin 0.0298793
RABGAP1 RAB GTPase activating protein 1 0.0297993
PAWR PRKC, apoptosis, WT1, regulator 0.0297656
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 0.0297312
SSH2 slingshot protein phosphatase 2 0.0297218
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0297048
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.0291105
C14ORF132 chromosome 14 open reading frame 132 0.0288243
RACK1 receptor for activated C kinase 1 0.0287699
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 0.0287333
WWOX WW domain containing oxidoreductase 0.0287303
JAK2 Janus kinase 2 0.0286119
SENP6 SUMO1/sentrin specific peptidase 6 0.0282453
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0282306
DST dystonin 0.0281976
RHOBTB3 Rho-related BTB domain containing 3 0.0276513
RAD51C RAD51 paralog C 0.0270594
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.027056
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.027043
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.0266322
ATOSA atos homolog A 0.0266035
SHISA9 shisa family member 9 0.0264618
ZNF83 zinc finger protein 83 0.0263606
RUNX1 runt-related transcription factor 1 0.0263392
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) 0.0262481
SPTSSB serine palmitoyltransferase, small subunit B 0.0259545
PHF21A PHD finger protein 21A 0.0258702
UBE2H ubiquitin-conjugating enzyme E2H 0.0257654
KANTR KDM5C adjacent non-coding transcript 0.0256999
MALRD1 MAM and LDL receptor class A domain containing 1 0.0256849
HSPB1 heat shock 27kDa protein 1 0.025647
POGZ pogo transposable element with ZNF domain 0.0255651
FERMT2 fermitin family member 2 0.0254155
COP1 COP1 E3 ubiquitin ligase 0.0253753
TOP1 topoisomerase (DNA) I 0.0251925
TAC4 tachykinin 4 (hemokinin) 0.024981
CABLES1 Cdk5 and Abl enzyme substrate 1 0.0249186
UBE3D ubiquitin protein ligase E3D 0.0249185
FLNB filamin B, beta 0.024707
ENOX2 ecto-NOX disulfide-thiol exchanger 2 0.0244825
TPD52L1 tumor protein D52-like 1 0.0244574
LURAP1L leucine rich adaptor protein 1-like 0.0243593
FGF12 fibroblast growth factor 12 0.0243039
KRT18 keratin 18, type I 0.024303
LTBP1 latent transforming growth factor beta binding protein 1 0.0242804
TSPAN12 tetraspanin 12 0.024193
BABAM2 BRISC and BRCA1 A complex member 2 0.0241492
COG7 component of oligomeric golgi complex 7 0.0240394
DUSP5 dual specificity phosphatase 5 0.0239711
MTA3 metastasis associated 1 family, member 3 0.0237209
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.023642
SGSM2 small G protein signaling modulator 2 0.0235481
DNAAF9 dynein axonemal assembly factor 9 0.0234855
LARP1B La ribonucleoprotein domain family, member 1B 0.0234563
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.0234277
CALCR calcitonin receptor 0.0233971
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 0.0233864
SREBF2 sterol regulatory element binding transcription factor 2 0.0233828
PSD3 pleckstrin and Sec7 domain containing 3 0.0232535
KAZN kazrin, periplakin interacting protein 0.0231941
GPATCH2 G patch domain containing 2 0.0230413
PTK2 protein tyrosine kinase 2 0.0230252
ASTN2 astrotactin 2 0.0229099
TRAPPC9 trafficking protein particle complex 9 0.0228202
RNF115 ring finger protein 115 0.02279
PHACTR4 phosphatase and actin regulator 4 0.0227658
SNX14 sorting nexin 14 0.0227449
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.022736
ERRFI1 ERBB receptor feedback inhibitor 1 0.0227113
LNX2 ligand of numb-protein X 2 0.022697
GREB1L growth regulation by estrogen in breast cancer-like 0.0226393
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.0225959
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.0223847
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 0.0223193
COX6C cytochrome c oxidase subunit VIc 0.022236
MIDEAS mitotic deacetylase associated SANT domain protein 0.0221539
MYH9 myosin, heavy chain 9, non-muscle 0.0220122
IARS1 isoleucyl-tRNA synthetase 1 0.021967
NONO non-POU domain containing, octamer-binding 0.0219017
ATXN2 ataxin 2 0.0218865
ARID4B AT rich interactive domain 4B (RBP1-like) 0.0218137
SNX29 sorting nexin 29 0.0217347
AHCYL2 adenosylhomocysteinase-like 2 0.0216815
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.0215527
IFI27 interferon, alpha-inducible protein 27 0.0215224
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 0.0215127
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.0214012
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 0.0212428
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.0212168
CHD6 chromodomain helicase DNA binding protein 6 0.021157
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.0210904
LPP LIM domain containing preferred translocation partner in lipoma 0.0208708
PDE8A phosphodiesterase 8A 0.0207978
RHPN2 rhophilin, Rho GTPase binding protein 2 0.0206654
LARP1 La ribonucleoprotein domain family, member 1 0.0204844
FIGN fidgetin 0.0201974
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 0.0201941
TIMP3 TIMP metallopeptidase inhibitor 3 0.0201856
FOS FBJ murine osteosarcoma viral oncogene homolog 0.0201514
NT5C3A 5'-nucleotidase, cytosolic IIIA 0.0200215
OTUD7B OTU deubiquitinase 7B 0.0199278
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.0199201
PLEKHA7 pleckstrin homology domain containing, family A member 7 0.0199051
IRS1 insulin receptor substrate 1 0.0198542
SINHCAF SIN3-HDAC complex associated factor 0.019797
SNX13 sorting nexin 13 0.0197868
SCAF11 SR-related CTD-associated factor 11 0.0197404
CNOT10 CCR4-NOT transcription complex, subunit 10 0.0196125
LOC102724023 ES1 protein homolog, mitochondrial 0.0195593
S100A11 S100 calcium binding protein A11 0.0195379
NT5DC3 5'-nucleotidase domain containing 3 0.019499
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 0.0194902
PRUNE1 prune exopolyphosphatase 1 0.0194255
NRDC nardilysin convertase 0.0194083
YIPF4 Yip1 domain family, member 4 0.0193767
MAP7 microtubule-associated protein 7 0.0193369
FBXO21 F-box protein 21 0.0193336
RPS18 ribosomal protein S18 0.0192903
MAN2C1 mannosidase, alpha, class 2C, member 1 0.0192849
ZMYM2 zinc finger, MYM-type 2 0.0191526
ANXA2 annexin A2 0.0191253
TMEM65 transmembrane protein 65 0.0191251
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 0.019112
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.0190585
WDR26 WD repeat domain 26 0.0190191
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 0.0190033
ZMYM4 zinc finger, MYM-type 4 0.0189524
MECP2 methyl CpG binding protein 2 0.0188952
HNMT histamine N-methyltransferase 0.0188935
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.0188821
SH3GLB2 SH3-domain GRB2-like endophilin B2 0.0188653
ISG15 ISG15 ubiquitin-like modifier 0.0187283
STC2 stanniocalcin 2 0.0185668
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.0185259
TXNIP thioredoxin interacting protein 0.0185206
DSTN destrin (actin depolymerizing factor) 0.0185092
AGR3 anterior gradient 3 0.0184778
TRRAP transformation/transcription domain-associated protein 0.0184589
PCLO piccolo presynaptic cytomatrix protein 0.0182777
TXNRD1 thioredoxin reductase 1 0.0182594
PBX3 pre-B-cell leukemia homeobox 3 0.0182302
KMT2A lysine (K)-specific methyltransferase 2A 0.0182116
PAN3 PAN3 poly(A) specific ribonuclease subunit 0.0182038
BCAS2 breast carcinoma amplified sequence 2 0.0182036
BASP1 brain abundant, membrane attached signal protein 1 0.0181726
ULK2 unc-51 like autophagy activating kinase 2 0.0181724
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.0181352
CEPT1 choline/ethanolamine phosphotransferase 1 0.0181175
TRIM56 tripartite motif containing 56 0.0181114
ARF4 ADP-ribosylation factor 4 0.0180491
TCF25 transcription factor 25 (basic helix-loop-helix) 0.018028
SIN3A SIN3 transcription regulator family member A 0.0179857
GNA14 guanine nucleotide binding protein (G protein), alpha 14 0.0178928
TRAFD1 TRAF-type zinc finger domain containing 1 0.0178703
COMMD1 copper metabolism (Murr1) domain containing 1 0.0178068
SASH1 SAM and SH3 domain containing 1 0.0177051
MB21D2 Mab-21 domain containing 2 0.0176632
ZNF251 zinc finger protein 251 0.0176496
SAMD1 sterile alpha motif domain containing 1 0.0176399
NELFCD negative elongation factor complex member C/D 0.01763
EEF2K eukaryotic elongation factor 2 kinase 0.0175987
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 0.0175564
SHTN1 shootin 1 0.0175068
SPIRE1 spire-type actin nucleation factor 1 0.0175038
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 0.0174862
TMEM131 transmembrane protein 131 0.0174748
PTPN14 protein tyrosine phosphatase, non-receptor type 14 0.0174429
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.0174204
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 0.0173231
SNX27 sorting nexin family member 27 0.0172945
RPS4X ribosomal protein S4, X-linked 0.0172801
UBP1 upstream binding protein 1 (LBP-1a) 0.0172796
FHL2 four and a half LIM domains 2 0.0171528
MBTD1 mbt domain containing 1 0.0171395
CD2AP CD2-associated protein 0.0171217
CDK13 cyclin-dependent kinase 13 0.0170905
EML5 echinoderm microtubule associated protein like 5 0.0170876
ZCCHC7 zinc finger, CCHC domain containing 7 0.017059
DCDC2 doublecortin domain containing 2 0.0169364
UTRN utrophin 0.0169048
PPP1R12B protein phosphatase 1, regulatory subunit 12B 0.0168944
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 0.0168707
CERT1 ceramide transporter 1 0.0167731
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.0167494
RC3H2 ring finger and CCCH-type domains 2 0.0167381
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.0167045
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 0.0166655
KATNA1 katanin p60 (ATPase containing) subunit A 1 0.0166547
RNF114 ring finger protein 114 0.01665
MAN1A1 mannosidase, alpha, class 1A, member 1 0.0166389
VSIG10 V-set and immunoglobulin domain containing 10 0.0166137
EPS8 epidermal growth factor receptor pathway substrate 8 0.016591
SLF2 SMC5-SMC6 complex localization factor 2 0.0165796
ANKRD50 ankyrin repeat domain 50 0.016569
RHEB Ras homolog enriched in brain 0.0165667
STXBP5 syntaxin binding protein 5 (tomosyn) 0.0165625
ACTR10 actin-related protein 10 homolog (S. cerevisiae) 0.0165571
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.01653
NMRAL1 NmrA-like family domain containing 1 0.0165182
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.0164768
MSL2 male-specific lethal 2 homolog (Drosophila) 0.0164387
CFAP161 cilia and flagella associated protein 161 0.016421
TRIP4 thyroid hormone receptor interactor 4 0.0163749
RNF216 ring finger protein 216 0.0163616
PSPC1 paraspeckle component 1 0.0163359
CBFB core-binding factor, beta subunit 0.0163354
ACAD10 acyl-CoA dehydrogenase family, member 10 0.016244
EZR ezrin 0.0161539
DEPTOR DEP domain containing MTOR-interacting protein 0.0161493
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) 0.0161368
RILPL1 Rab interacting lysosomal protein-like 1 0.0161218
ZNF804B zinc finger protein 804B 0.016072
DIPK2A divergent protein kinase domain 2A 0.016038
RPL19 ribosomal protein L19 0.0160368
RTF2 replication termination factor 2 0.0159898
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 0.0159656
ITCH itchy E3 ubiquitin protein ligase 0.0158297
FBXO34 F-box protein 34 0.0157073
LRRC1 leucine rich repeat containing 1 0.0156773
LGALS3 lectin, galactoside-binding, soluble, 3 0.0156419
PRR12 proline rich 12 0.0156027
IP6K2 inositol hexakisphosphate kinase 2 0.0155848
RNFT1 ring finger protein, transmembrane 1 0.0155631
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 0.0155461
GSN gelsolin 0.0154838
SPATS2 spermatogenesis associated, serine-rich 2 0.0154772
SPPL2A signal peptide peptidase like 2A 0.0154292
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta 0.0154133
EGR1 early growth response 1 0.0153919
GLRA3 glycine receptor, alpha 3 0.0153766
PRUNE2 prune homolog 2 (Drosophila) 0.0153714
AAGAB alpha- and gamma-adaptin binding protein 0.0153464
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 0.0153191
MORF4L2 mortality factor 4 like 2 0.0153046
TSC22D2 TSC22 domain family, member 2 0.0152784
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0152544
LYPLAL1 lysophospholipase-like 1 0.0151915
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.0151862
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.0151619
ZFAND3 zinc finger, AN1-type domain 3 0.0151243
SGMS1 sphingomyelin synthase 1 0.0151151
COMMD10 COMM domain containing 10 0.0150959
RIPOR3 RIPOR family member 3 0.0150716
NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 0.0150549
LDLR low density lipoprotein receptor 0.0150198
CENPC centromere protein C 0.0149649
GMPS guanine monphosphate synthase 0.0149608
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.0149486
TDRD3 tudor domain containing 3 0.0149443
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 0.0148658
MYB v-myb avian myeloblastosis viral oncogene homolog 0.0148623
DNM2 dynamin 2 0.0148569
ZNF718 zinc finger protein 718 0.0148494
ANKRD26 ankyrin repeat domain 26 0.0148479
CCNC cyclin C 0.0148396
H3C4 H3 clustered histone 4 0.0148389
BMP5 bone morphogenetic protein 5 0.0148221
SAMD12 sterile alpha motif domain containing 12 0.0148221
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 0.014763
PDCD6 programmed cell death 6 0.0146893
QPCTL glutaminyl-peptide cyclotransferase-like 0.0146812
RPL18 ribosomal protein L18 0.01465
SKAP2 src kinase associated phosphoprotein 2 0.0146448
GRID1 glutamate receptor, ionotropic, delta 1 0.0146378
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.0146293
ENTREP1 endosomal transmembrane epsin interactor 1 0.0146091
RALGDS ral guanine nucleotide dissociation stimulator 0.014602
ACVR1B activin A receptor, type IB 0.0145338
ICA1 islet cell autoantigen 1, 69kDa 0.0145036
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 0.0144929
CAV1 caveolin 1, caveolae protein, 22kDa 0.0144619
LITAF lipopolysaccharide-induced TNF factor 0.0144617
RASA2 RAS p21 protein activator 2 0.0144436
CDC37L1 cell division cycle 37-like 1 0.0144249
MTREX Mtr4 exosome RNA helicase 0.0143305
ETF1 eukaryotic translation termination factor 1 0.0143262
PHF20 PHD finger protein 20 0.0143161
FBXO42 F-box protein 42 0.0142984
SLC25A43 solute carrier family 25, member 43 0.014297
ZFP36L1 ZFP36 ring finger protein-like 1 0.0142943
STRBP spermatid perinuclear RNA binding protein 0.0142804
NBPF15 neuroblastoma breakpoint family, member 15 0.0142626
TBCE tubulin folding cofactor E 0.0142622
STARD10 StAR-related lipid transfer (START) domain containing 10 0.0142387
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 0.0142225
AXIN1 axin 1 0.0141942
METTL16 methyltransferase like 16 0.0141882
COBL cordon-bleu WH2 repeat protein 0.0140952
PLD3 phospholipase D family, member 3 0.0140909
BCL10 B-cell CLL/lymphoma 10 0.0140738
SLC16A6 solute carrier family 16, member 6 0.0140664
TRIM33 tripartite motif containing 33 0.0140585
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0140264
TTC8 tetratricopeptide repeat domain 8 0.0140182
RAB10 RAB10, member RAS oncogene family 0.0140099
ERMP1 endoplasmic reticulum metallopeptidase 1 0.0139551
STK38 serine/threonine kinase 38 0.0139502
STK40 serine/threonine kinase 40 0.0139458
USP43 ubiquitin specific peptidase 43 0.0139452
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 0.0139437
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 0.0139427
TEX14 testis expressed 14 0.0139081
IQSEC2 IQ motif and Sec7 domain 2 0.0138836
DUSP16 dual specificity phosphatase 16 0.0138788
AHI1 Abelson helper integration site 1 0.0138747
BMS1 BMS1 ribosome biogenesis factor 0.0138078
TOGARAM1 TOG array regulator of axonemal microtubules 1 0.0137961
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 0.0137943
TTC17 tetratricopeptide repeat domain 17 0.0137841
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 0.0137801
KCTD20 potassium channel tetramerization domain containing 20 0.0137585
ATL2 atlastin GTPase 2 0.0137507
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) 0.0137157
ORAI2 ORAI calcium release-activated calcium modulator 2 0.0137008
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 0.0136593
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 0.0136554
JMY junction mediating and regulatory protein, p53 cofactor 0.0136334
ARSG arylsulfatase G 0.0136194
RASEF RAS and EF-hand domain containing 0.0136168
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 0.0135969
ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif, 17 0.0135649
NEK11 NIMA-related kinase 11 0.0135558
AEBP2 AE binding protein 2 0.0135082
IGFBP4 insulin-like growth factor binding protein 4 0.0135019
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa 0.0134966
PCDH9 protocadherin 9 0.0134889
MTMR6 myotubularin related protein 6 0.0134878
GRB2 growth factor receptor-bound protein 2 0.0134818
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.0134787
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0134759
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 0.0134742
CSAD cysteine sulfinic acid decarboxylase 0.0134403
PLPP3 phospholipid phosphatase 3 0.0134311
SEPTIN9 septin 9 0.0134215
TMCC1 transmembrane and coiled-coil domain family 1 0.0134114
HOOK2 hook microtubule-tethering protein 2 0.0133953
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.0133807
SEC63 SEC63 homolog (S. cerevisiae) 0.0133782
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 0.0133764
CDC27 cell division cycle 27 0.0133506
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 0.0133294
MBOAT1 membrane bound O-acyltransferase domain containing 1 0.0133184
KARS1 lysyl-tRNA synthetase 1 0.0133146
NCAPG2 non-SMC condensin II complex, subunit G2 0.0133008
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.0132944
NXNL2 nucleoredoxin-like 2 0.0132929
KIAA0232 KIAA0232 0.0132827
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.0132678
ZCCHC14 zinc finger, CCHC domain containing 14 0.0132666
ELF2 E74-like factor 2 (ets domain transcription factor) 0.013254
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 0.0132536
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.0132533
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.0132275
SETD2 SET domain containing 2 0.0132126
PNPLA8 patatin-like phospholipase domain containing 8 0.0132122
SETD1B SET domain containing 1B 0.0132058
CCDC83 coiled-coil domain containing 83 0.01319
MED13 mediator complex subunit 13 0.013176
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like 0.0131746
PRAG1 PEAK1 related, kinase-activating pseudokinase 1 0.0131725
NADSYN1 NAD synthetase 1 0.013135
ETNK1 ethanolamine kinase 1 0.0131326
STAG2 stromal antigen 2 0.0131225
MKNK1 MAP kinase interacting serine/threonine kinase 1 0.0131222
DNAAF3 dynein, axonemal, assembly factor 3 0.0131172
CAMTA1 calmodulin binding transcription activator 1 0.0131062
BACE1 beta-site APP-cleaving enzyme 1 0.013094
USP15 ubiquitin specific peptidase 15 0.0130934
DAPK3 death-associated protein kinase 3 0.0130842
FBXO33 F-box protein 33 0.0130758
MAP3K21 mitogen-activated protein kinase kinase kinase 21 0.0130712
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant 0.0130336
BRWD1 bromodomain and WD repeat domain containing 1 0.0130181
PPP6C protein phosphatase 6, catalytic subunit 0.0130145
ELL elongation factor RNA polymerase II 0.0129878
SPICE1 spindle and centriole associated protein 1 0.012977
C1ORF21 chromosome 1 open reading frame 21 0.0129553
EFL1 elongation factor like GTPase 1 0.0129373
INTS7 integrator complex subunit 7 0.0129342
POLK polymerase (DNA directed) kappa 0.012933
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 0.0128585
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 0.0128476
WEE1 WEE1 G2 checkpoint kinase 0.0128299
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 0.0128276
LUC7L LUC7-like (S. cerevisiae) 0.0128083
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 0.0127897
C2ORF92 chromosome 2 open reading frame 92 0.0127863
FOXP1 forkhead box P1 0.0127793
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 0.0127727
TRPS1 trichorhinophalangeal syndrome I 0.0127679
BIRC6 baculoviral IAP repeat containing 6 0.0127637
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.012714
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.0127083
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.012706
RAP2C RAP2C, member of RAS oncogene family 0.0126969
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0126942
RFX7 regulatory factor X, 7 0.0126898
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.0126806
BUD31 BUD31 homolog (S. cerevisiae) 0.0126696
TOR1AIP2 torsin A interacting protein 2 0.0126603
SMG6 SMG6 nonsense mediated mRNA decay factor 0.0126545
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 0.0126517
SLC30A5 solute carrier family 30 (zinc transporter), member 5 0.0126407
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 0.0126347
METTL22 methyltransferase like 22 0.0126235
LMNA lamin A/C 0.0126158
OSGIN2 oxidative stress induced growth inhibitor family member 2 0.0126099
FN1 fibronectin 1 0.0125912
SMC3 structural maintenance of chromosomes 3 0.0125834
FRMD4B FERM domain containing 4B 0.0125785
GANAB glucosidase, alpha; neutral AB 0.0125783
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.0125598
METRNL meteorin, glial cell differentiation regulator-like 0.012553
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein 0.0125512
TNRC18 trinucleotide repeat containing 18 0.0125038
TPR translocated promoter region, nuclear basket protein 0.0124889
TENT4B terminal nucleotidyltransferase 4B 0.0124762
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.0124743
JUN jun proto-oncogene 0.0124439
CCDC6 coiled-coil domain containing 6 0.0124291
PER2 period circadian clock 2 0.0124119
DMXL2 Dmx-like 2 0.0124109
STX16 syntaxin 16 0.01241
ELP4 elongator acetyltransferase complex subunit 4 0.0123855
NUMA1 nuclear mitotic apparatus protein 1 0.0123795
NFU1 NFU1 iron-sulfur cluster scaffold 0.012337
CENPE centromere protein E, 312kDa 0.0123249
CHEK2 checkpoint kinase 2 0.0123096
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 0.0122926
CFAP44 cilia and flagella associated protein 44 0.0122803
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.0122764
TMEM33 transmembrane protein 33 0.01225
INO80D INO80 complex subunit D 0.0122459
MTX2 metaxin 2 0.0122344
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 0.0122317
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.0122009
UIMC1 ubiquitin interaction motif containing 1 0.0121754
APOD apolipoprotein D 0.012174
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 0.012159
PHC3 polyhomeotic homolog 3 (Drosophila) 0.012158
NBEAL1 neurobeachin-like 1 0.0121193
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.0121013
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.0121003
IDE insulin-degrading enzyme 0.0120983
AUTS2 autism susceptibility candidate 2 0.0120947
COL12A1 collagen, type XII, alpha 1 0.012088
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.0120875

decreased expression

Symbol Name Standardized Value
TFF1 trefoil factor 1 -0.135423
GFRA1 GDNF family receptor alpha 1 -0.116062
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.114067
IGF1R insulin-like growth factor 1 receptor -0.11286
CTSD cathepsin D -0.107003
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.105489
MRPL13 mitochondrial ribosomal protein L13 -0.104297
PKM pyruvate kinase, muscle -0.090103
RPS8 ribosomal protein S8 -0.0880955
PRRC2B proline-rich coiled-coil 2B -0.0754675
ATAD2 ATPase family, AAA domain containing 2 -0.0667251
PTPRK protein tyrosine phosphatase, receptor type, K -0.0663804
RPLP1 ribosomal protein, large, P1 -0.0655444
RPS17 ribosomal protein S17 -0.0634431
RPS2 ribosomal protein S2 -0.0615281
RPL30 ribosomal protein L30 -0.0594609
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.055693
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0554765
BMP7 bone morphogenetic protein 7 -0.0547694
PRR11 proline rich 11 -0.0543635
MKI67 marker of proliferation Ki-67 -0.052476
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0516494
ZNF217 zinc finger protein 217 -0.0511328
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0505775
CALR calreticulin -0.0502656
TPT1 tumor protein, translationally-controlled 1 -0.0484583
TMOD3 tropomodulin 3 (ubiquitous) -0.0480233
BRI3BP BRI3 binding protein -0.0475239
CLTC clathrin, heavy chain (Hc) -0.0474701
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.0468769
ACTG1 actin gamma 1 -0.045546
RPL28 ribosomal protein L28 -0.0439914
MTDH metadherin -0.0436031
FLNA filamin A, alpha -0.0429034
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 -0.0428243
AGR2 anterior gradient 2 -0.0419383
RPL15 ribosomal protein L15 -0.0416389
RPS6 ribosomal protein S6 -0.0414984
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0411356
RPL12 ribosomal protein L12 -0.0410914
NSD1 nuclear receptor binding SET domain protein 1 -0.0407758
SND1 staphylococcal nuclease and tudor domain containing 1 -0.0405827
CD81 CD81 molecule -0.0403471
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0399492
ATXN1 ataxin 1 -0.0397489
CANX calnexin -0.0389919
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -0.0381874
MAVS mitochondrial antiviral signaling protein -0.0380727
RPL37A ribosomal protein L37a -0.0380495
TPI1 triosephosphate isomerase 1 -0.0373862
POTEF POTE ankyrin domain family, member F -0.0370819
PRKCA protein kinase C, alpha -0.0368717
PARD3 par-3 family cell polarity regulator -0.0366103
RPS29 ribosomal protein S29 -0.0364637
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.0358458
RTN4 reticulon 4 -0.0355049
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.035121
GOLGA4 golgin A4 -0.0350724
RPS11 ribosomal protein S11 -0.0348072
ELP2 elongator acetyltransferase complex subunit 2 -0.0344771
UBE2K ubiquitin-conjugating enzyme E2K -0.0337361
TP53 tumor protein p53 -0.0336761
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -0.0333974
ANKRD11 ankyrin repeat domain 11 -0.0332468
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.0331622
LARP4B La ribonucleoprotein domain family, member 4B -0.0328775
GPC6 glypican 6 -0.032508
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0323548
GOLGA2 golgin A2 -0.0322515
RPS7 ribosomal protein S7 -0.0322392
FAF1 Fas (TNFRSF6) associated factor 1 -0.0321094
CADM1 cell adhesion molecule 1 -0.0320993
SMYD3 SET and MYND domain containing 3 -0.0320788
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -0.0318698
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0318312
RPL13A ribosomal protein L13a -0.0318249
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -0.0317875
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.0317488
FBXL17 F-box and leucine-rich repeat protein 17 -0.0317199
RPL32 ribosomal protein L32 -0.031701
PDIA6 protein disulfide isomerase family A, member 6 -0.0316766
SVIL supervillin -0.0314088
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) -0.0311521
CENPB centromere protein B, 80kDa -0.0310725
MED13L mediator complex subunit 13-like -0.0309026
CCNI cyclin I -0.0306035
HDLBP high density lipoprotein binding protein -0.0305022
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.0302722
RPS3 ribosomal protein S3 -0.0302635
MYO10 myosin X -0.0302615
EVL Enah/Vasp-like -0.0302414
PDS5B PDS5 cohesin associated factor B -0.0302341
PLEC plectin -0.0302274
SYTL2 synaptotagmin-like 2 -0.0302099
RPL7A ribosomal protein L7a -0.0294008
HMCN1 hemicentin 1 -0.0293713
RAB6A RAB6A, member RAS oncogene family -0.0293601
WASF2 WAS protein family, member 2 -0.029221
UBC ubiquitin C -0.0291944
KPNB1 karyopherin (importin) beta 1 -0.0291331
EEF2 eukaryotic translation elongation factor 2 -0.0289804
CLDN7 claudin 7 -0.0287999
GDI2 GDP dissociation inhibitor 2 -0.0287854
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -0.0286714
MACROH2A1 macroH2A.1 histone -0.0284833
RPLP0 ribosomal protein, large, P0 -0.0284103
SPPL3 signal peptide peptidase like 3 -0.0282178
BCLAF1 BCL2-associated transcription factor 1 -0.0278635
PRRC2C proline-rich coiled-coil 2C -0.0277901
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0277697
PTGES3 prostaglandin E synthase 3 (cytosolic) -0.0277692
KAT6B K(lysine) acetyltransferase 6B -0.0276496
SFTPA2 surfactant protein A2 -0.0275095
CENPF centromere protein F, 350/400kDa -0.0274125
FANCA Fanconi anemia, complementation group A -0.0271478
NECAB1 N-terminal EF-hand calcium binding protein 1 -0.0271302
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.0270257
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.026993
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0269364
RPS14 ribosomal protein S14 -0.0266891
GATAD2B GATA zinc finger domain containing 2B -0.0265442
CA12 carbonic anhydrase XII -0.0261531
PRIM2 primase, DNA, polypeptide 2 (58kDa) -0.025992
DSG2 desmoglein 2 -0.025814
ZBTB7A zinc finger and BTB domain containing 7A -0.0258126
MLXIP MLX interacting protein -0.0257637
TMSB4X thymosin beta 4, X-linked -0.0257588
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -0.0256059
BPTF bromodomain PHD finger transcription factor -0.0255726
HACD2 3-hydroxyacyl-CoA dehydratase 2 -0.0254759
FBXO11 F-box protein 11 -0.0254574
TBC1D5 TBC1 domain family, member 5 -0.0253866
SRPK2 SRSF protein kinase 2 -0.0253497
RPL23A ribosomal protein L23a -0.0252069
MYO1E myosin IE -0.0250376
SIPA1L1 signal-induced proliferation-associated 1 like 1 -0.0250063
MREG melanoregulin -0.024674
FREM2 FRAS1 related extracellular matrix protein 2 -0.0246242
NEMF nuclear export mediator factor -0.0246083
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 -0.0245538
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.0241911
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.0240078
METAP2 methionyl aminopeptidase 2 -0.0239518
TUFM Tu translation elongation factor, mitochondrial -0.0239248
MLEC malectin -0.0238818
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 -0.0238411
RPS19 ribosomal protein S19 -0.0237871
NSD3 nuclear receptor binding SET domain protein 3 -0.0236476
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0236447
RABL6 RAB, member RAS oncogene family-like 6 -0.0236193
ANKRD12 ankyrin repeat domain 12 -0.0234892
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) -0.0233479
CDC42 cell division cycle 42 -0.023295
ZFHX3 zinc finger homeobox 3 -0.0232702
CHD8 chromodomain helicase DNA binding protein 8 -0.023259
EIF3A eukaryotic translation initiation factor 3, subunit A -0.0232291
ADCY9 adenylate cyclase 9 -0.0232048
EPN2 epsin 2 -0.0231962
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -0.023193
TASOR2 transcription activation suppressor family member 2 -0.0230879
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.0230797
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -0.0230487
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0229788
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0229213
SEL1L sel-1 suppressor of lin-12-like (C. elegans) -0.0228037
RPL35 ribosomal protein L35 -0.022685
NHP2 NHP2 ribonucleoprotein -0.0226662
FAM120A family with sequence similarity 120A -0.0226489
TBL1X transducin (beta)-like 1X-linked -0.0226488
LRP1B low density lipoprotein receptor-related protein 1B -0.0226094
PTTG1IP pituitary tumor-transforming 1 interacting protein -0.0226009
NOTCH3 notch 3 -0.0225384
H2AZ1 H2A.Z variant histone 1 -0.0225254
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0225229
PCYOX1 prenylcysteine oxidase 1 -0.02248
YME1L1 YME1-like 1 ATPase -0.0224271
RRBP1 ribosome binding protein 1 -0.0224261
P4HB prolyl 4-hydroxylase, beta polypeptide -0.022387
CERS6 ceramide synthase 6 -0.0223761
ENSA endosulfine alpha -0.022368
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0222992
CUX1 cut-like homeobox 1 -0.0222656
LAMP2 lysosomal-associated membrane protein 2 -0.0222633
RPL36A ribosomal protein L36a -0.0221554
TMEM164 transmembrane protein 164 -0.0219952
FRYL FRY-like -0.0219503
EIF5 eukaryotic translation initiation factor 5 -0.0219142
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -0.0218952
RNF130 ring finger protein 130 -0.0218117
CCNK cyclin K -0.0216883
EIF4B eukaryotic translation initiation factor 4B -0.0216468
TRIO trio Rho guanine nucleotide exchange factor -0.021597
CLASP1 cytoplasmic linker associated protein 1 -0.0215568
GPATCH8 G patch domain containing 8 -0.0214715
BBX bobby sox homolog (Drosophila) -0.0212997
PRC1 protein regulator of cytokinesis 1 -0.0212985
MBNL1 muscleblind-like splicing regulator 1 -0.0212087
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 -0.0212045
DENR density-regulated protein -0.0211839
TMPO thymopoietin -0.0211488
INTS2 integrator complex subunit 2 -0.0211003
TRIM28 tripartite motif containing 28 -0.0210829
ZDHHC20 zinc finger, DHHC-type containing 20 -0.0210613
BICDL1 BICD family like cargo adaptor 1 -0.0210516
OXR1 oxidation resistance 1 -0.0209888
NRP1 neuropilin 1 -0.0209469
RPS25 ribosomal protein S25 -0.0209174
ADGRL1 adhesion G protein-coupled receptor L1 -0.0208704
RPS5 ribosomal protein S5 -0.0208114
ZNFX1 zinc finger, NFX1-type containing 1 -0.0207674
HELZ helicase with zinc finger -0.0207638
SCRN1 secernin 1 -0.0207568
NF1 neurofibromin 1 -0.0207413
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.0206178
MASTL microtubule associated serine/threonine kinase-like -0.0205086
KIF13A kinesin family member 13A -0.0204477
ACBD6 acyl-CoA binding domain containing 6 -0.0204159
PFDN4 prefoldin subunit 4 -0.020404
EXT1 exostosin glycosyltransferase 1 -0.0203917
RAD23A RAD23 homolog A (S. cerevisiae) -0.0203591
EXOC4 exocyst complex component 4 -0.0203451
SF3B2 splicing factor 3b, subunit 2, 145kDa -0.020328
AGO3 argonaute RISC catalytic component 3 -0.0203101
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.0202906
NCOA2 nuclear receptor coactivator 2 -0.0202471
GSE1 Gse1 coiled-coil protein -0.0202071
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0201882
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -0.020083
DPY19L4 dpy-19-like 4 (C. elegans) -0.0200358
FNDC3B fibronectin type III domain containing 3B -0.0199702
ACTN4 actinin, alpha 4 -0.0199201
MBD5 methyl-CpG binding domain protein 5 -0.0197909
PRLR prolactin receptor -0.0197541
CREB1 cAMP responsive element binding protein 1 -0.0197237
MAST2 microtubule associated serine/threonine kinase 2 -0.0197185
ERBB3 erb-b2 receptor tyrosine kinase 3 -0.019702
SAMD4A sterile alpha motif domain containing 4A -0.019699
KIDINS220 kinase D-interacting substrate, 220kDa -0.0196891
TCF20 transcription factor 20 (AR1) -0.0196813
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.019656
TMEM178B transmembrane protein 178B -0.019649
WDR73 WD repeat domain 73 -0.0195821
HMGB1 high mobility group box 1 -0.0195699
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -0.0195663
ASCC1 activating signal cointegrator 1 complex subunit 1 -0.0195387
APP amyloid beta (A4) precursor protein -0.0195009
NOVA1 neuro-oncological ventral antigen 1 -0.0194902
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0194897
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -0.0194868
RAB31 RAB31, member RAS oncogene family -0.0194834
FOXA1 forkhead box A1 -0.0194709
CST3 cystatin C -0.0194483
FNDC3A fibronectin type III domain containing 3A -0.0194296
PATJ PATJ crumbs cell polarity complex component -0.0194292
COPE coatomer protein complex, subunit epsilon -0.0193894
SAPCD2 suppressor APC domain containing 2 -0.0193361
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B -0.0193297
UBR2 ubiquitin protein ligase E3 component n-recognin 2 -0.0192814
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -0.0192473
JARID2 jumonji, AT rich interactive domain 2 -0.019197
MEIS2 Meis homeobox 2 -0.0191665
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -0.019052
ANKIB1 ankyrin repeat and IBR domain containing 1 -0.0190176
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -0.0189868
SMIM44 small integral membrane protein 44 -0.0189121
HDAC8 histone deacetylase 8 -0.0188588
TET2 tet methylcytosine dioxygenase 2 -0.0188125
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.0187543
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -0.0187301
PDXK pyridoxal (pyridoxine, vitamin B6) kinase -0.0187119
MRPS25 mitochondrial ribosomal protein S25 -0.0187096
COL4A5 collagen, type IV, alpha 5 -0.0187057
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit -0.0187034
FOXK2 forkhead box K2 -0.0186704
PTPRG protein tyrosine phosphatase, receptor type, G -0.0186503
EIF1 eukaryotic translation initiation factor 1 -0.018555
RPS12 ribosomal protein S12 -0.0185538
RPN1 ribophorin I -0.018549
MYO5A myosin VA (heavy chain 12, myoxin) -0.0185317
MYOF myoferlin -0.0185083
CMIP c-Maf inducing protein -0.0183593
MAML3 mastermind-like 3 (Drosophila) -0.0182794
HDGF hepatoma-derived growth factor -0.0182652
PLXNA4 plexin A4 -0.0182168
PLXDC2 plexin domain containing 2 -0.0182022
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -0.0181811
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -0.01818
NBEA neurobeachin -0.0181664
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -0.018164
BAZ1B bromodomain adjacent to zinc finger domain, 1B -0.0181546
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 -0.0181454
CLSTN2 calsyntenin 2 -0.0180845
LDLRAD3 low density lipoprotein receptor class A domain containing 3 -0.0180834
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 -0.0180633
TGFB2 transforming growth factor, beta 2 -0.0180163
DAND5 DAN domain family member 5, BMP antagonist -0.0180007
MAN1A2 mannosidase, alpha, class 1A, member 2 -0.0179464
ZNF33A zinc finger protein 33A -0.0179436
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.0179282
CERCAM cerebral endothelial cell adhesion molecule -0.0179092
ARTN artemin -0.0179067
FTH1 ferritin, heavy polypeptide 1 -0.01788
UNK unkempt family zinc finger -0.0177586
IST1 increased sodium tolerance 1 homolog (yeast) -0.0176351
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 -0.0176121
AP2S1 adaptor-related protein complex 2, sigma 1 subunit -0.0176021
EIF3E eukaryotic translation initiation factor 3, subunit E -0.0175928
KLHL5 kelch-like family member 5 -0.0175877
PEAK1 pseudopodium-enriched atypical kinase 1 -0.017555
CBX3 chromobox homolog 3 -0.0175548
LRP10 low density lipoprotein receptor-related protein 10 -0.0175276
PFKP phosphofructokinase, platelet -0.01747
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.0174371
CHD4 chromodomain helicase DNA binding protein 4 -0.0174082
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0174074
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -0.0173774
CCN5 cellular communication network factor 5 -0.0172781
HLTF helicase-like transcription factor -0.0172703
CD276 CD276 molecule -0.0172407
NR6A1 nuclear receptor subfamily 6, group A, member 1 -0.0172264
SPIDR scaffolding protein involved in DNA repair -0.0172235
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -0.0171828
KMT5B lysine methyltransferase 5B -0.0171677
RPS27A ribosomal protein S27a -0.0171159
LRPPRC leucine-rich pentatricopeptide repeat containing -0.0170951
RPL38 ribosomal protein L38 -0.016986
ALG8 ALG8, alpha-1,3-glucosyltransferase -0.0169855
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha -0.016858
MED12L mediator complex subunit 12-like -0.0168381
PRKCSH protein kinase C substrate 80K-H -0.0168332
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 -0.016808
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed -0.0167835
TUBA1B tubulin, alpha 1b -0.0167454
OSBPL1A oxysterol binding protein-like 1A -0.0167286
SORCS1 sortilin-related VPS10 domain containing receptor 1 -0.0166681
MCM4 minichromosome maintenance complex component 4 -0.0166107
MPDU1 mannose-P-dolichol utilization defect 1 -0.0166041
DHDDS dehydrodolichyl diphosphate synthase -0.0165849
SLC35F5 solute carrier family 35, member F5 -0.0165491
WDR33 WD repeat domain 33 -0.0165485
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.0165186
ESYT1 extended synaptotagmin-like protein 1 -0.0164644
ATP5F1B ATP synthase F1 subunit beta -0.0164264
FRMD5 FERM domain containing 5 -0.0163933
SSBP2 single-stranded DNA binding protein 2 -0.0163285
RSF1 remodeling and spacing factor 1 -0.0162925
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -0.0162539
ZNF207 zinc finger protein 207 -0.0162348
RAB1B RAB1B, member RAS oncogene family -0.0162289
HSPA8 heat shock 70kDa protein 8 -0.0162128
FAM168A family with sequence similarity 168, member A -0.0161987
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -0.0161858
CPNE3 copine III -0.0161609
PXDN peroxidasin -0.0161095
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -0.0160972
TRAM1 translocation associated membrane protein 1 -0.0160812
RDX radixin -0.016063
RPL18A ribosomal protein L18a -0.0160148
NEO1 neogenin 1 -0.0160024
PCSK6 proprotein convertase subtilisin/kexin type 6 -0.0159976
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) -0.0159844
MGA MGA, MAX dimerization protein -0.0159779
CYB561 cytochrome b561 -0.0159528
TOPBP1 topoisomerase (DNA) II binding protein 1 -0.0159003
HIPK2 homeodomain interacting protein kinase 2 -0.0158965
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -0.0158951
TMEM43 transmembrane protein 43 -0.0158872
GINS2 GINS complex subunit 2 (Psf2 homolog) -0.0158748
LRIF1 ligand dependent nuclear receptor interacting factor 1 -0.0158486
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.0158445
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 -0.0158133
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -0.0158124
MAP3K20 mitogen-activated protein kinase kinase kinase 20 -0.0158109
VIRMA vir like m6A methyltransferase associated -0.0157971
KIF2A kinesin heavy chain member 2A -0.0157147
TRIM44 tripartite motif containing 44 -0.0156894
KIAA1958 KIAA1958 -0.0156808
RPL8 ribosomal protein L8 -0.0156611
TRA2B transformer 2 beta homolog (Drosophila) -0.0156491
TUBB tubulin, beta class I -0.015619
TACSTD2 tumor-associated calcium signal transducer 2 -0.0156086
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -0.0156065
RNGTT RNA guanylyltransferase and 5'-phosphatase -0.0155904
MAPK8 mitogen-activated protein kinase 8 -0.0155697
RPS16 ribosomal protein S16 -0.0155692
MRFAP1 Morf4 family associated protein 1 -0.0155536
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.0155264
ARL15 ADP-ribosylation factor-like 15 -0.0155159
TBC1D16 TBC1 domain family, member 16 -0.0155027
CCT2 chaperonin containing TCP1, subunit 2 (beta) -0.0154967
RPL29 ribosomal protein L29 -0.015485
GAPVD1 GTPase activating protein and VPS9 domains 1 -0.0154808
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.0154693
ERCC6 excision repair cross-complementation group 6 -0.0154679
NPNT nephronectin -0.0154605
TUG1 taurine up-regulated 1 (non-protein coding) -0.0154379
DOCK9 dedicator of cytokinesis 9 -0.015428
RPL4 ribosomal protein L4 -0.0154012
CEP78 centrosomal protein 78kDa -0.0153912
ATXN7L3B ataxin 7-like 3B -0.0153898
KYNU kynureninase -0.0153444
ITM2B integral membrane protein 2B -0.0153353
MRTFA myocardin related transcription factor A -0.0153333
WWP2 WW domain containing E3 ubiquitin protein ligase 2 -0.015326
NPDC1 neural proliferation, differentiation and control, 1 -0.0153032
MTMR3 myotubularin related protein 3 -0.0152971
SOGA1 suppressor of glucose, autophagy associated 1 -0.015276
SEC16A SEC16 homolog A (S. cerevisiae) -0.0152049
AFF4 AF4/FMR2 family, member 4 -0.0151788
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 -0.0151782
AP2A1 adaptor-related protein complex 2, alpha 1 subunit -0.0151744
DHFR dihydrofolate reductase -0.0151733
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -0.0151643
LIMS1 LIM and senescent cell antigen-like domains 1 -0.0151619
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 -0.0151202
SCARB2 scavenger receptor class B, member 2 -0.0151027
CDC42SE2 CDC42 small effector 2 -0.0151014
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -0.0150685
SNX17 sorting nexin 17 -0.0150489
CAMK1D calcium/calmodulin-dependent protein kinase ID -0.0150332
MANBA mannosidase, beta A, lysosomal -0.015023
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -0.0150177
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -0.0150168
POLR1D polymerase (RNA) I polypeptide D, 16kDa -0.0150093
EPHA4 EPH receptor A4 -0.0150019
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0149974
SPTAN1 spectrin, alpha, non-erythrocytic 1 -0.0149971
REEP5 receptor accessory protein 5 -0.0149749
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -0.0149586
SH3RF1 SH3 domain containing ring finger 1 -0.0149151
FARSB phenylalanyl-tRNA synthetase, beta subunit -0.0148962
KPNA1 karyopherin alpha 1 (importin alpha 5) -0.0148861
GSTCD glutathione S-transferase, C-terminal domain containing -0.0148605
ENOSF1 enolase superfamily member 1 -0.014792
PTRH2 peptidyl-tRNA hydrolase 2 -0.014776
TRIM27 tripartite motif containing 27 -0.0147702
RPL23 ribosomal protein L23 -0.0147517
INSR insulin receptor -0.0147165
CARM1 coactivator-associated arginine methyltransferase 1 -0.0147054
KAT6A K(lysine) acetyltransferase 6A -0.0146832
THOC7 THO complex 7 -0.014639
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 -0.0146283
TOP2B topoisomerase (DNA) II beta 180kDa -0.0146164
SLC38A1 solute carrier family 38, member 1 -0.0145995
GLI3 GLI family zinc finger 3 -0.0145786
EYA3 EYA transcriptional coactivator and phosphatase 3 -0.0145635
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) -0.0145603
UBA2 ubiquitin-like modifier activating enzyme 2 -0.0145579
SLC12A9 solute carrier family 12, member 9 -0.0145421
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -0.0145209
CENPK centromere protein K -0.0144968
ZNF75D zinc finger protein 75D -0.0144324
MARVELD2 MARVEL domain containing 2 -0.0144313
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 -0.0144303
CATSPERB catsper channel auxiliary subunit beta -0.0144065
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase -0.0144048
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -0.0144042
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) -0.014403
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa -0.0144022
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -0.0143443
ACLY ATP citrate lyase -0.0143327
RPLP2 ribosomal protein, large, P2 -0.0143117
INVS inversin -0.0143094
GEMIN5 gem (nuclear organelle) associated protein 5 -0.0143064
GRN granulin -0.0142844
XPO4 exportin 4 -0.0142814
MTSS1 metastasis suppressor 1 -0.0142757
ASCC3 activating signal cointegrator 1 complex subunit 3 -0.0142491
TPD52L2 tumor protein D52-like 2 -0.0142392
LDOC1 leucine zipper, down-regulated in cancer 1 -0.014235
PPP1R12A protein phosphatase 1, regulatory subunit 12A -0.0142343
CEP55 centrosomal protein 55kDa -0.0142303
TNPO2 transportin 2 -0.0141652
KDM3B lysine (K)-specific demethylase 3B -0.0141492
FLOT1 flotillin 1 -0.0141425
TLN2 talin 2 -0.0141321
RPS24 ribosomal protein S24 -0.0140768
CHURC1 churchill domain containing 1 -0.0140639
MACROD1 MACRO domain containing 1 -0.0140571
PEDS1 plasmanylethanolamine desaturase 1 -0.0140511
GOLPH3 golgi phosphoprotein 3 (coat-protein) -0.0140417
MIA3 melanoma inhibitory activity family, member 3 -0.0140347
DGKH diacylglycerol kinase, eta -0.0140314
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -0.0139894
NHSL1 NHS-like 1 -0.0139833
SPAG9 sperm associated antigen 9 -0.0139797
XPOT exportin, tRNA -0.0139129
TTC28 tetratricopeptide repeat domain 28 -0.0138963
NOL4L nucleolar protein 4-like -0.0138844
BRD2 bromodomain containing 2 -0.0138758
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma -0.013868
NINL ninein-like -0.0138666
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.0138564
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 -0.0138538
SLC38A10 solute carrier family 38, member 10 -0.0138537
SLK STE20-like kinase -0.0138323
ITPK1 inositol-tetrakisphosphate 1-kinase -0.0138237
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C -0.0138177
KANSL1 KAT8 regulatory NSL complex subunit 1 -0.0138177
U2SURP U2 snRNP-associated SURP domain containing -0.0138016