MCF7_SNS-314 Mesylate_10µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description SNS-314 Mesylate 10µM perturbation in MCF7 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the MCF7_SNS-314 Mesylate_10µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
ZNF217 zinc finger protein 217 0.12943
HSPB1 heat shock 27kDa protein 1 0.109025
BCAS3 breast carcinoma amplified sequence 3 0.104186
NAV1 neuron navigator 1 0.0998046
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.0920953
USP32 ubiquitin specific peptidase 32 0.0899025
CCND1 cyclin D1 0.0890312
TRIM37 tripartite motif containing 37 0.0873406
SYTL2 synaptotagmin-like 2 0.0839615
SMAD3 SMAD family member 3 0.0816159
IGF1R insulin-like growth factor 1 receptor 0.0809734
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0798329
MRPL13 mitochondrial ribosomal protein L13 0.0710097
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.07025
TFF1 trefoil factor 1 0.069143
FOXP1 forkhead box P1 0.0690111
FLNA filamin A, alpha 0.0689753
AREG amphiregulin 0.062348
CUEDC1 CUE domain containing 1 0.0602632
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.0598361
RPL12 ribosomal protein L12 0.0580473
NT5C2 5'-nucleotidase, cytosolic II 0.0572397
DTNA dystrobrevin, alpha 0.055176
PBX1 pre-B-cell leukemia homeobox 1 0.05418
KRT81 keratin 81, type II 0.0539331
POTEF POTE ankyrin domain family, member F 0.0525281
KRT80 keratin 80, type II 0.05153
ATXN1 ataxin 1 0.0495624
RPS11 ribosomal protein S11 0.0489145
SAMD12 sterile alpha motif domain containing 12 0.0483928
CSDE1 cold shock domain containing E1, RNA-binding 0.0476329
GTF2IRD1 GTF2I repeat domain containing 1 0.0474141
RPS18 ribosomal protein S18 0.0460317
ACTG1 actin gamma 1 0.0456926
BCAS4 breast carcinoma amplified sequence 4 0.0453561
PACS1 phosphofurin acidic cluster sorting protein 1 0.0451638
GSE1 Gse1 coiled-coil protein 0.0449955
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0449884
RPL15 ribosomal protein L15 0.0448544
RPL37A ribosomal protein L37a 0.044416
WWP1 WW domain containing E3 ubiquitin protein ligase 1 0.0439324
ZFAND3 zinc finger, AN1-type domain 3 0.0438068
ENSA endosulfine alpha 0.0425494
RPS2 ribosomal protein S2 0.0425339
ANKRD11 ankyrin repeat domain 11 0.0424387
SEPTIN9 septin 9 0.0423127
VMP1 vacuole membrane protein 1 0.041788
RAD51B RAD51 paralog B 0.0417235
SARS2 seryl-tRNA synthetase 2, mitochondrial 0.0411925
PTK2 protein tyrosine kinase 2 0.0399891
MLPH melanophilin 0.0394561
MSI2 musashi RNA-binding protein 2 0.0384419
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.0378629
IARS1 isoleucyl-tRNA synthetase 1 0.0376321
AARS1 alanyl-tRNA synthetase 1 0.0376079
RPL13A ribosomal protein L13a 0.0369883
RPLP0 ribosomal protein, large, P0 0.0363858
ERRFI1 ERBB receptor feedback inhibitor 1 0.0363413
PAWR PRKC, apoptosis, WT1, regulator 0.0361675
ARFGEF3 ARFGEF family member 3 0.0358256
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0354832
FNBP4 formin binding protein 4 0.0350958
RPL18 ribosomal protein L18 0.0349794
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.0348934
CADPS2 Ca++-dependent secretion activator 2 0.0348857
FHIT fragile histidine triad 0.034834
RACK1 receptor for activated C kinase 1 0.0348194
THOC2 THO complex 2 0.0340427
LARP4B La ribonucleoprotein domain family, member 4B 0.0335022
LPP LIM domain containing preferred translocation partner in lipoma 0.0332552
GDF15 growth differentiation factor 15 0.0330415
ANKRD28 ankyrin repeat domain 28 0.0330137
COG5 component of oligomeric golgi complex 5 0.0330134
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 0.032814
SETD5 SET domain containing 5 0.0325842
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.0318952
EHMT1 euchromatic histone-lysine N-methyltransferase 1 0.0317976
RPS8 ribosomal protein S8 0.0317844
RBPMS RNA binding protein with multiple splicing 0.0313789
BAIAP2L1 BAI1-associated protein 2-like 1 0.0310062
RPS5 ribosomal protein S5 0.030971
RPS6 ribosomal protein S6 0.0308025
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.0307893
PSME4 proteasome (prosome, macropain) activator subunit 4 0.0306918
ZNF292 zinc finger protein 292 0.0304865
ASCC3 activating signal cointegrator 1 complex subunit 3 0.0303597
TBL1X transducin (beta)-like 1X-linked 0.0301927
PAN3 PAN3 poly(A) specific ribonuclease subunit 0.0301193
ZFP36L1 ZFP36 ring finger protein-like 1 0.0299768
RBM47 RNA binding motif protein 47 0.0296505
LGALS3 lectin, galactoside-binding, soluble, 3 0.02958
UBL4A ubiquitin-like 4A 0.0295311
XBP1 X-box binding protein 1 0.0292001
RPS19 ribosomal protein S19 0.028891
BCAS1 breast carcinoma amplified sequence 1 0.0288192
TRIM33 tripartite motif containing 33 0.0286495
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.0282527
SRPK2 SRSF protein kinase 2 0.0280293
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.0280221
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0279173
EEIG1 estrogen-induced osteoclastogenesis regulator 1 0.0278704
SOX4 SRY (sex determining region Y)-box 4 0.0277784
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.027016
RPS3 ribosomal protein S3 0.026838
IER5L immediate early response 5-like 0.0268205
TTC28 tetratricopeptide repeat domain 28 0.0267592
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.0264523
FOXA1 forkhead box A1 0.0263759
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.02637
MACC1 metastasis associated in colon cancer 1 0.0263139
RPS17 ribosomal protein S17 0.0259997
TNIK TRAF2 and NCK interacting kinase 0.0258821
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0258033
SPIRE1 spire-type actin nucleation factor 1 0.0256862
FOXO1 forkhead box O1 0.0255386
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0254788
RPL14 ribosomal protein L14 0.0252767
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.025252
RPL30 ribosomal protein L30 0.0252264
CXXC5 CXXC finger protein 5 0.025167
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.0251066
NAV2 neuron navigator 2 0.024914
RPL29 ribosomal protein L29 0.0248972
NR6A1 nuclear receptor subfamily 6, group A, member 1 0.0248829
GOLGA4 golgin A4 0.0245863
RPL35A ribosomal protein L35a 0.0245762
TBC1D5 TBC1 domain family, member 5 0.0245012
STRBP spermatid perinuclear RNA binding protein 0.0240922
BABAM2 BRISC and BRCA1 A complex member 2 0.0240097
CLDN4 claudin 4 0.0235827
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.0235727
SQSTM1 sequestosome 1 0.0233812
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.0232317
RPL11 ribosomal protein L11 0.0232235
ZCCHC7 zinc finger, CCHC domain containing 7 0.0231325
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.0228441
RPS24 ribosomal protein S24 0.0228432
ATXN2 ataxin 2 0.022811
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.0227144
TRIO trio Rho guanine nucleotide exchange factor 0.0226427
FNDC3B fibronectin type III domain containing 3B 0.0226294
RNF216 ring finger protein 216 0.0224617
ARID4B AT rich interactive domain 4B (RBP1-like) 0.0224577
PTPRE protein tyrosine phosphatase, receptor type, E 0.0223988
DOP1B DOP1 leucine zipper like protein B 0.022209
RPS29 ribosomal protein S29 0.0221772
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.022166
STK39 serine threonine kinase 39 0.0220724
SAMD4A sterile alpha motif domain containing 4A 0.0219895
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.0219667
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0219382
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.0219169
EIF4B eukaryotic translation initiation factor 4B 0.0219003
LHFPL2 lipoma HMGIC fusion partner-like 2 0.021721
PRRC2C proline-rich coiled-coil 2C 0.0216243
ARHGAP12 Rho GTPase activating protein 12 0.0216106
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.0215893
N4BP2L2 NEDD4 binding protein 2-like 2 0.0212799
NCOA3 nuclear receptor coactivator 3 0.0211081
TASOR2 transcription activation suppressor family member 2 0.0210915
USP3 ubiquitin specific peptidase 3 0.0208507
GAB2 GRB2-associated binding protein 2 0.020848
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.0208468
CLIP1 CAP-GLY domain containing linker protein 1 0.020735
ORAI2 ORAI calcium release-activated calcium modulator 2 0.0207001
ATP9A ATPase, class II, type 9A 0.0206587
PRKCA protein kinase C, alpha 0.0206362
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.0206263
CCDC125 coiled-coil domain containing 125 0.0206041
TIAM1 T-cell lymphoma invasion and metastasis 1 0.0205895
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.0204882
WSB1 WD repeat and SOCS box containing 1 0.0202708
BLTP1 bridge-like lipid transfer protein family member 1 0.0202024
FGF13 fibroblast growth factor 13 0.0201804
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.0199527
ZMIZ1 zinc finger, MIZ-type containing 1 0.0199325
CELF1 CUGBP, Elav-like family member 1 0.0198773
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 0.0197507
HDAC8 histone deacetylase 8 0.0196345
AVL9 AVL9 homolog (S. cerevisiase) 0.0195878
STC2 stanniocalcin 2 0.0195782
WWC1 WW and C2 domain containing 1 0.0195561
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.0195454
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0195089
APP amyloid beta (A4) precursor protein 0.0194319
WNK1 WNK lysine deficient protein kinase 1 0.0193481
RPS7 ribosomal protein S7 0.0193037
NCKAP1 NCK-associated protein 1 0.0192957
NIBAN2 niban apoptosis regulator 2 0.0192955
MYADM myeloid-associated differentiation marker 0.0192859
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0192215
BMP7 bone morphogenetic protein 7 0.0191958
CLDN3 claudin 3 0.0191924
GNA14 guanine nucleotide binding protein (G protein), alpha 14 0.0190675
PRDX5 peroxiredoxin 5 0.0187875
BRD3 bromodomain containing 3 0.0187461
UBE2I ubiquitin-conjugating enzyme E2I 0.0186025
TNPO3 transportin 3 0.0185492
RPS16 ribosomal protein S16 0.0184776
UBE3C ubiquitin protein ligase E3C 0.0184552
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 0.0184232
CLTC clathrin, heavy chain (Hc) 0.0183427
ADGRG6 adhesion G protein-coupled receptor G6 0.0183109
RPS13 ribosomal protein S13 0.0182691
RPL19 ribosomal protein L19 0.0182418
RPL28 ribosomal protein L28 0.0180958
S100A14 S100 calcium binding protein A14 0.0180748
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 0.0180577
IRF2BP2 interferon regulatory factor 2 binding protein 2 0.0180276
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) 0.0180259
ADAM10 ADAM metallopeptidase domain 10 0.0180204
MAPK6 mitogen-activated protein kinase 6 0.0180024
CENPB centromere protein B, 80kDa 0.017972
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.0179458
FNBP1 formin binding protein 1 0.0179333
RPS9 ribosomal protein S9 0.0178979
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 0.0178545
RPL6 ribosomal protein L6 0.0178397
TANK TRAF family member-associated NFKB activator 0.0178245
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.0178187
CFAP97D1 CFAP97 domain containing 1 0.0178046
MTSS1 metastasis suppressor 1 0.0177913
PRKCH protein kinase C, eta 0.0177407
ESYT2 extended synaptotagmin-like protein 2 0.0177226
GMDS GDP-mannose 4,6-dehydratase 0.0177177
EIF3E eukaryotic translation initiation factor 3, subunit E 0.0177166
RPS27 ribosomal protein S27 0.0174966
ZNF148 zinc finger protein 148 0.0174601
ABLIM1 actin binding LIM protein 1 0.01745
RPSA ribosomal protein SA 0.0174217
RAB7A RAB7A, member RAS oncogene family 0.0174095
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.0173672
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.0173628
SPAG9 sperm associated antigen 9 0.0172373
RPL18A ribosomal protein L18a 0.0171914
BMERB1 bMERB domain containing 1 0.0170379
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0170355
TACSTD2 tumor-associated calcium signal transducer 2 0.0170251
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.0170088
LCOR ligand dependent nuclear receptor corepressor 0.016985
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.0169579
LARP4 La ribonucleoprotein domain family, member 4 0.0168727
CYRIB CYFIP related Rac1 interactor B 0.0168032
SRRM2 serine/arginine repetitive matrix 2 0.0167497
AQP3 aquaporin 3 (Gill blood group) 0.0166726
SRBD1 S1 RNA binding domain 1 0.0166353
CARMIL1 capping protein regulator and myosin 1 linker 1 0.0166149
BRWD1 bromodomain and WD repeat domain containing 1 0.01656
CLMN calmin (calponin-like, transmembrane) 0.0165212
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.0165014
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.0164969
ZMYND8 zinc finger, MYND-type containing 8 0.016445
PGPEP1 pyroglutamyl-peptidase I 0.0164143
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.0163839
BLTP3A bridge-like lipid transfer protein family member 3A 0.0162968
SVIL supervillin 0.01626
ECPAS Ecm29 proteasome adaptor and scaffold 0.0162092
SUMF1 sulfatase modifying factor 1 0.0161933
KIAA1217 KIAA1217 0.0161549
MON2 MON2 homolog (S. cerevisiae) 0.0158398
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 0.0158066
KLHL24 kelch-like family member 24 0.0158062
CAPN8 calpain 8 0.015746
CDPF1 cysteine-rich, DPF motif domain containing 1 0.0157157
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 0.0157134
RAD9A RAD9 homolog A (S. pombe) 0.0157092
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.0157092
SET SET nuclear proto-oncogene 0.0155636
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0155374
PRPF38B pre-mRNA processing factor 38B 0.0155085
RPL3 ribosomal protein L3 0.0155011
EIF5B eukaryotic translation initiation factor 5B 0.0154708
IWS1 IWS1 homolog (S. cerevisiae) 0.0154559
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.015362
CLU clusterin 0.0153399
CUX1 cut-like homeobox 1 0.0153386
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 0.0153348
IL4R interleukin 4 receptor 0.0152681
SEPTIN11 septin 11 0.0152189
SH3D19 SH3 domain containing 19 0.0152183
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.015206
SIMC1 SUMO-interacting motifs containing 1 0.0152055
DNMBP dynamin binding protein 0.0151721
NCOR2 nuclear receptor corepressor 2 0.0150824
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 0.0150651
RHOC ras homolog family member C 0.0150258
CCAR1 cell division cycle and apoptosis regulator 1 0.0150053
HIBADH 3-hydroxyisobutyrate dehydrogenase 0.0150032
KPNA6 karyopherin alpha 6 (importin alpha 7) 0.0149954
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.0149704
ACTN1 actinin, alpha 1 0.0149541
ZDHHC7 zinc finger, DHHC-type containing 7 0.0149022
SASH1 SAM and SH3 domain containing 1 0.0148691
RBMS1 RNA binding motif, single stranded interacting protein 1 0.0148683
MAP4 microtubule-associated protein 4 0.0148567
GATAD2B GATA zinc finger domain containing 2B 0.0148442
FTH1 ferritin, heavy polypeptide 1 0.0147776
RSL1D1 ribosomal L1 domain containing 1 0.0147573
ACYP2 acylphosphatase 2, muscle type 0.0147136
TPR translocated promoter region, nuclear basket protein 0.0146704
RPL8 ribosomal protein L8 0.0146229
CCDC88C coiled-coil domain containing 88C 0.0146188
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0145504
RPL32 ribosomal protein L32 0.0145143
PDLIM5 PDZ and LIM domain 5 0.0145056
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.0144531
OSBPL1A oxysterol binding protein-like 1A 0.0143885
TKT transketolase 0.0143174
FOXO3 forkhead box O3 0.0143122
SLA2 Src-like-adaptor 2 0.0142303
TTF1 transcription termination factor, RNA polymerase I 0.014202
ITCH itchy E3 ubiquitin protein ligase 0.0141975
CALU calumenin 0.0141919
GOLM2 golgi membrane protein 2 0.014177
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.0141466
RPS14 ribosomal protein S14 0.014111
DENND1A DENN/MADD domain containing 1A 0.0140888
ZNFX1 zinc finger, NFX1-type containing 1 0.0140476
ABHD2 abhydrolase domain containing 2 0.0140227
ANKIB1 ankyrin repeat and IBR domain containing 1 0.0140175
FTL ferritin, light polypeptide 0.0140144
TBC1D16 TBC1 domain family, member 16 0.0140123
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 0.0139911
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 0.0139351
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 0.0138103
MTDH metadherin 0.0137909
MEF2A myocyte enhancer factor 2A 0.0137902
PRSS8 protease, serine, 8 0.0137864
PLD3 phospholipase D family, member 3 0.0137851
MLEC malectin 0.0137377
PRKX protein kinase, X-linked 0.0137363
VEZF1 vascular endothelial zinc finger 1 0.0137254
GIPC1 GIPC PDZ domain containing family, member 1 0.013682
NUMB numb homolog (Drosophila) 0.0136771
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0136115
SYNGAP1 synaptic Ras GTPase activating protein 1 0.0135749
CDYL2 chromodomain protein, Y-like 2 0.0135671
ATXN3 ataxin 3 0.0135657
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.0135546
SH3RF1 SH3 domain containing ring finger 1 0.0135091
ETFA electron-transfer-flavoprotein, alpha polypeptide 0.0134785
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.0134032
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 0.0133199
HEATR6 HEAT repeat containing 6 0.0131006
SEC31A SEC31 homolog A (S. cerevisiae) 0.0130917
NOTCH2 notch 2 0.0130102
ECE1 endothelin converting enzyme 1 0.0129916
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.0129295
VIRMA vir like m6A methyltransferase associated 0.012902
KLF3 Kruppel-like factor 3 (basic) 0.012899
GEMIN5 gem (nuclear organelle) associated protein 5 0.0128927
TMPRSS4 transmembrane protease, serine 4 0.0128878
WWC3 WWC family member 3 0.0128771
NEMF nuclear export mediator factor 0.0128684
DDIT4 DNA-damage-inducible transcript 4 0.0127797
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 0.0127419
IGF2R insulin-like growth factor 2 receptor 0.0127335
RPL4 ribosomal protein L4 0.0127323
STX16 syntaxin 16 0.0127085
RPL21 ribosomal protein L21 0.0126893
ERBIN erbb2 interacting protein 0.0126795
SND1 staphylococcal nuclease and tudor domain containing 1 0.0126621
IREB2 iron-responsive element binding protein 2 0.0126073
ZBTB46 zinc finger and BTB domain containing 46 0.0125695
KMT2C lysine (K)-specific methyltransferase 2C 0.0125461
SETD2 SET domain containing 2 0.0125428
PTMA prothymosin, alpha 0.0125364
YME1L1 YME1-like 1 ATPase 0.0124919
NOL10 nucleolar protein 10 0.0124074
FAM107B family with sequence similarity 107, member B 0.0123891
SNED1 sushi, nidogen and EGF-like domains 1 0.0123491
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.0123077
LARS1 leucyl-tRNA synthetase 1 0.0122778
ITGB6 integrin, beta 6 0.0122649
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 0.0122489
ZNF609 zinc finger protein 609 0.0122385
STOX2 storkhead box 2 0.012232
SBF2 SET binding factor 2 0.0122128
SKIL SKI-like proto-oncogene 0.0122108
DMGDH dimethylglycine dehydrogenase 0.0122057
SUGP2 SURP and G patch domain containing 2 0.0122045
EXOC4 exocyst complex component 4 0.0122014
TXNRD1 thioredoxin reductase 1 0.0121792
BRD4 bromodomain containing 4 0.0121473
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.0121464
PDZD8 PDZ domain containing 8 0.0121461
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.0121456
ZNF91 zinc finger protein 91 0.0121351
HSPA4 heat shock 70kDa protein 4 0.0121307
PCDHB16 protocadherin beta 16 0.0120832
ZNF710 zinc finger protein 710 0.0120546
ZBTB7A zinc finger and BTB domain containing 7A 0.0120427
GSN gelsolin 0.0120425
CYTH1 cytohesin 1 0.0120321
SAMD8 sterile alpha motif domain containing 8 0.0120301
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0120099
MAP1B microtubule-associated protein 1B 0.0120027
PUM1 pumilio RNA-binding family member 1 0.011991
ERBB3 erb-b2 receptor tyrosine kinase 3 0.0119626
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.0119338
EMSY EMSY transcriptional repressor, BRCA2 interacting 0.0119241
NUDCD3 NudC domain containing 3 0.0118983
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 0.0118837
CHD9 chromodomain helicase DNA binding protein 9 0.0118602
RPL27A ribosomal protein L27a 0.0118445
R3HDM1 R3H domain containing 1 0.011839
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.0118371
MREG melanoregulin 0.0117873
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.0117847
RPL7A ribosomal protein L7a 0.0117454
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 0.0117395
CAMKMT calmodulin-lysine N-methyltransferase 0.0117143
TUT7 terminal uridylyl transferase 7 0.01171
GLO1 glyoxalase I 0.0117054
BBX bobby sox homolog (Drosophila) 0.0117053
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 0.0116986
UBC ubiquitin C 0.0116951
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.0116682
RHOQ ras homolog family member Q 0.0116639
SHROOM3 shroom family member 3 0.0116631
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0116378
UBE2G1 ubiquitin-conjugating enzyme E2G 1 0.0116328
FOXN3 forkhead box N3 0.0116173
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.0115926
BMPR1A bone morphogenetic protein receptor, type IA 0.0115835
ATF7IP2 activating transcription factor 7 interacting protein 2 0.0115829
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.0115825
RAB5A RAB5A, member RAS oncogene family 0.0115675
FOXK1 forkhead box K1 0.0115436
KDM4B lysine (K)-specific demethylase 4B 0.0115087
ADCY5 adenylate cyclase 5 0.0115014
LASP1 LIM and SH3 protein 1 0.0114996
INSR insulin receptor 0.0114933
GCN1 GCN1 activator of EIF2AK4 0.0114811
PPP4R2 protein phosphatase 4, regulatory subunit 2 0.0114628
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.0114338
UBAP1 ubiquitin associated protein 1 0.0114233
TRAF3 TNF receptor-associated factor 3 0.0113737
APOLD1 apolipoprotein L domain containing 1 0.011367
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1 0.0113608
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.0113396
LDAH lipid droplet associated hydrolase 0.0113148
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.0112826
SUCO SUN domain containing ossification factor 0.0112693
AAK1 AP2 associated kinase 1 0.0112502
TPD52 tumor protein D52 0.0112485
SH3PXD2A SH3 and PX domains 2A 0.0112257
PCNX1 pecanex 1 0.0112162
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 0.0112112
POM121 POM121 transmembrane nucleoporin 0.0111904
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.0111875
SH3BGRL SH3 domain binding glutamate-rich protein like 0.0111633
OAZ1 ornithine decarboxylase antizyme 1 0.0111565
CDYL chromodomain protein, Y-like 0.0111534
OCLN occludin 0.0111404
TLK2 tousled-like kinase 2 0.0111381
ARHGAP32 Rho GTPase activating protein 32 0.0110962
IP6K1 inositol hexakisphosphate kinase 1 0.0110748
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.0110668
RSL24D1 ribosomal L24 domain containing 1 0.0110476
PRXL2A peroxiredoxin like 2A 0.0110472
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.0110237
SLK STE20-like kinase 0.0110085
NBPF15 neuroblastoma breakpoint family, member 15 0.010989
DDX55 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 0.010984
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 0.0109808
MXD1 MAX dimerization protein 1 0.0109564
RNF41 ring finger protein 41, E3 ubiquitin protein ligase 0.0109556
ADAR adenosine deaminase, RNA-specific 0.0109546
METTL2A methyltransferase like 2A 0.0109476
CAPZB capping protein (actin filament) muscle Z-line, beta 0.0109449
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) 0.0109197
CBX1 chromobox homolog 1 0.0109165
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.0109052
ESRRA estrogen-related receptor alpha 0.0109049
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.0108995
RSF1 remodeling and spacing factor 1 0.0108992
CD63 CD63 molecule 0.0108839
KMT2E lysine (K)-specific methyltransferase 2E 0.0108586
MLXIP MLX interacting protein 0.0108478
C1ORF159 chromosome 1 open reading frame 159 0.0108349
RPLP2 ribosomal protein, large, P2 0.0108295
UBE2H ubiquitin-conjugating enzyme E2H 0.0107942
MORC3 MORC family CW-type zinc finger 3 0.0107868
HEATR1 HEAT repeat containing 1 0.0107584
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0107574
TMSB4X thymosin beta 4, X-linked 0.0107504
PTEN phosphatase and tensin homolog 0.0107413
TBC1D14 TBC1 domain family, member 14 0.0107381
YPEL2 yippee-like 2 (Drosophila) 0.0107371
GCC2 GRIP and coiled-coil domain containing 2 0.0107296
MAP7 microtubule-associated protein 7 0.0107262
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.0107153
UBE3A ubiquitin protein ligase E3A 0.0106953
RPL36 ribosomal protein L36 0.0106856
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) 0.0106805
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase 0.0106345
TMOD3 tropomodulin 3 (ubiquitous) 0.0106287
GLDN gliomedin 0.0106178
MARK3 MAP/microtubule affinity-regulating kinase 3 0.010602

decreased expression

Symbol Name Standardized Value
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.201107
GFRA1 GDNF family receptor alpha 1 -0.198734
KRT8 keratin 8, type II -0.168856
MALRD1 MAM and LDL receptor class A domain containing 1 -0.148463
ESR1 estrogen receptor 1 -0.14265
EVL Enah/Vasp-like -0.129585
GATA3 GATA binding protein 3 -0.119366
SULF2 sulfatase 2 -0.116829
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.116368
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.115748
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.107565
WWOX WW domain containing oxidoreductase -0.107324
PLXDC2 plexin domain containing 2 -0.102946
PKM pyruvate kinase, muscle -0.0833205
AGR2 anterior gradient 2 -0.0807663
NRCAM neuronal cell adhesion molecule -0.080257
GPC6 glypican 6 -0.0757771
EMP2 epithelial membrane protein 2 -0.0703747
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0695412
BPTF bromodomain PHD finger transcription factor -0.0668702
MKI67 marker of proliferation Ki-67 -0.064376
KRT19 keratin 19, type I -0.0630609
SLC38A1 solute carrier family 38, member 1 -0.0627873
TRPS1 trichorhinophalangeal syndrome I -0.0618493
ENO1 enolase 1, (alpha) -0.0616765
MED13L mediator complex subunit 13-like -0.0611884
ATAD2 ATPase family, AAA domain containing 2 -0.0602337
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) -0.0599237
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.055698
MACROD2 MACRO domain containing 2 -0.0548233
H3-3B H3.3 histone B -0.0543282
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.0537629
TMEM164 transmembrane protein 164 -0.0522809
PARD3 par-3 family cell polarity regulator -0.0504555
CTNND2 catenin (cadherin-associated protein), delta 2 -0.0493652
PBX3 pre-B-cell leukemia homeobox 3 -0.0490876
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0486729
NRG3 neuregulin 3 -0.0470115
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 -0.0468974
TMEM150C transmembrane protein 150C -0.0460453
SDK1 sidekick cell adhesion molecule 1 -0.0449288
MAST4 microtubule associated serine/threonine kinase family member 4 -0.0445039
THSD4 thrombospondin, type I, domain containing 4 -0.0436617
ADCY1 adenylate cyclase 1 (brain) -0.0429839
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 -0.0427485
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.0425288
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.0414595
NCKAP5 NCK-associated protein 5 -0.0395923
NRIP1 nuclear receptor interacting protein 1 -0.0394977
BASP1 brain abundant, membrane attached signal protein 1 -0.0391794
CADM1 cell adhesion molecule 1 -0.0381721
CALCR calcitonin receptor -0.0372849
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0369776
PTPRG protein tyrosine phosphatase, receptor type, G -0.0359219
KAT6B K(lysine) acetyltransferase 6B -0.0357093
PCDH7 protocadherin 7 -0.0354261
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 -0.0350609
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.0341811
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0337287
TPM4 tropomyosin 4 -0.0336972
BCL2 B-cell CLL/lymphoma 2 -0.0328677
PARD6B par-6 family cell polarity regulator beta -0.032721
KYNU kynureninase -0.0323634
AKAP9 A kinase (PRKA) anchor protein 9 -0.0321729
ERBB4 erb-b2 receptor tyrosine kinase 4 -0.0321606
HMCN1 hemicentin 1 -0.0316527
IRS1 insulin receptor substrate 1 -0.0315379
LRP1B low density lipoprotein receptor-related protein 1B -0.0311934
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 -0.0311379
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0310988
ACSL3 acyl-CoA synthetase long-chain family member 3 -0.0307092
FGF12 fibroblast growth factor 12 -0.0306753
PLEC plectin -0.0303854
CLSTN2 calsyntenin 2 -0.0303468
MB21D2 Mab-21 domain containing 2 -0.0296983
LMBR1 limb development membrane protein 1 -0.0296645
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -0.0296241
SIDT1 SID1 transmembrane family, member 1 -0.0292463
NECAB1 N-terminal EF-hand calcium binding protein 1 -0.0281627
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0280967
CENPP centromere protein P -0.0279535
TMEM64 transmembrane protein 64 -0.0277243
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -0.0276093
MYOF myoferlin -0.0273234
PARD3B par-3 family cell polarity regulator beta -0.0272192
IFI6 interferon, alpha-inducible protein 6 -0.0270632
DCDC2 doublecortin domain containing 2 -0.0270582
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.027013
NPAS3 neuronal PAS domain protein 3 -0.0264804
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0263747
TET2 tet methylcytosine dioxygenase 2 -0.0263332
MED13 mediator complex subunit 13 -0.0261389
RAB31 RAB31, member RAS oncogene family -0.0261176
CTSD cathepsin D -0.0258406
CEMIP2 cell migration inducing hyaluronidase 2 -0.0255905
TPI1 triosephosphate isomerase 1 -0.0255478
AMZ1 archaelysin family metallopeptidase 1 -0.0253497
RGS6 regulator of G-protein signaling 6 -0.0252581
COX6C cytochrome c oxidase subunit VIc -0.0248798
RHOBTB3 Rho-related BTB domain containing 3 -0.0248159
IQGAP1 IQ motif containing GTPase activating protein 1 -0.0248057
SPTSSB serine palmitoyltransferase, small subunit B -0.0247614
SFXN2 sideroflexin 2 -0.0247015
ARL15 ADP-ribosylation factor-like 15 -0.0246623
SYT1 synaptotagmin I -0.0246159
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.0245242
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 -0.0245169
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0242116
CHLSN cholesin -0.0240349
RCOR1 REST corepressor 1 -0.0239414
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -0.0239162
TUG1 taurine up-regulated 1 (non-protein coding) -0.0238522
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0237102
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0235889
GPATCH2 G patch domain containing 2 -0.0231173
FRMD5 FERM domain containing 5 -0.0229874
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0229849
MYO5C myosin VC -0.0227056
SMIM14 small integral membrane protein 14 -0.0226592
TPM3 tropomyosin 3 -0.0226569
TMBIM6 transmembrane BAX inhibitor motif containing 6 -0.0226419
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -0.0225268
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.0224168
FREM2 FRAS1 related extracellular matrix protein 2 -0.0223706
LDLR low density lipoprotein receptor -0.0223453
AHNAK AHNAK nucleoprotein -0.0221485
KSR2 kinase suppressor of ras 2 -0.0220928
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -0.0220772
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.0220477
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.021977
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.021933
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) -0.0219285
GABPB2 GA binding protein transcription factor, beta subunit 2 -0.0217937
PKP4 plakophilin 4 -0.0217842
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 -0.0217423
UBTF upstream binding transcription factor, RNA polymerase I -0.0214423
ATXN7L1 ataxin 7-like 1 -0.0213958
KRT18 keratin 18, type I -0.0213911
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -0.0213108
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -0.0211408
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B -0.0210754
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 -0.0210297
RC3H1 ring finger and CCCH-type domains 1 -0.0209999
ELF2 E74-like factor 2 (ets domain transcription factor) -0.0208271
FBXL17 F-box and leucine-rich repeat protein 17 -0.0207831
ARHGAP24 Rho GTPase activating protein 24 -0.0207167
STXBP5 syntaxin binding protein 5 (tomosyn) -0.0207121
ITPRID2 ITPR interacting domain containing 2 -0.0204904
NPNT nephronectin -0.0204454
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -0.0204334
VCP valosin containing protein -0.0203354
NUP160 nucleoporin 160kDa -0.0203245
ADIPOR2 adiponectin receptor 2 -0.0203055
LYPD6 LY6/PLAUR domain containing 6 -0.0203035
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0202164
PRLR prolactin receptor -0.0201587
STARD10 StAR-related lipid transfer (START) domain containing 10 -0.020134
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.0200947
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 -0.0200474
PRKCE protein kinase C, epsilon -0.0199879
DIAPH1 diaphanous-related formin 1 -0.0198664
NCAM2 neural cell adhesion molecule 2 -0.019865
PRC1 protein regulator of cytokinesis 1 -0.0198004
CLPTM1 cleft lip and palate associated transmembrane protein 1 -0.0195732
S100A10 S100 calcium binding protein A10 -0.0194475
TRIP12 thyroid hormone receptor interactor 12 -0.0193299
AK1 adenylate kinase 1 -0.0193209
MCM4 minichromosome maintenance complex component 4 -0.019292
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.0192395
UGDH UDP-glucose 6-dehydrogenase -0.0192058
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.0190169
MAP3K2 mitogen-activated protein kinase kinase kinase 2 -0.0189097
KANSL1 KAT8 regulatory NSL complex subunit 1 -0.0188022
JAK1 Janus kinase 1 -0.0186849
EXT1 exostosin glycosyltransferase 1 -0.0184646
PCYOX1 prenylcysteine oxidase 1 -0.0184355
TRERF1 transcriptional regulating factor 1 -0.0183527
SETX senataxin -0.0181488
DENND1B DENN/MADD domain containing 1B -0.0179462
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 -0.0179435
GPR137 G protein-coupled receptor 137 -0.0179387
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like -0.0178888
KDM2A lysine (K)-specific demethylase 2A -0.0178812
CBX5 chromobox homolog 5 -0.017739
KNL1 kinetochore scaffold 1 -0.0177121
OSBPL10 oxysterol binding protein-like 10 -0.0176738
SIK3 SIK family kinase 3 -0.0175897
PDZRN3 PDZ domain containing ring finger 3 -0.01748
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1 -0.0174735
CRYBG1 crystallin beta-gamma domain containing 1 -0.0174656
BRCA1 breast cancer 1, early onset -0.0174184
FBP1 fructose-1,6-bisphosphatase 1 -0.0173915
RNF43 ring finger protein 43 -0.017298
RERE arginine-glutamic acid dipeptide (RE) repeats -0.017298
TRIM24 tripartite motif containing 24 -0.017295
NCOA2 nuclear receptor coactivator 2 -0.0172828
PTPN1 protein tyrosine phosphatase, non-receptor type 1 -0.0172792
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.0172471
CENPF centromere protein F, 350/400kDa -0.0171224
DHCR7 7-dehydrocholesterol reductase -0.0171199
EPHA7 EPH receptor A7 -0.0169196
CDH18 cadherin 18, type 2 -0.0168758
EXOC6 exocyst complex component 6 -0.0168634
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -0.0167107
SMYD3 SET and MYND domain containing 3 -0.0166875
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0165754
VDAC2 voltage-dependent anion channel 2 -0.0165301
MVD mevalonate (diphospho) decarboxylase -0.0164244
UBE2K ubiquitin-conjugating enzyme E2K -0.0163565
MYO16 myosin XVI -0.0161493
ZFHX3 zinc finger homeobox 3 -0.0161035
GPR137C G protein-coupled receptor 137C -0.0160433
SNX29 sorting nexin 29 -0.0160426
CEP350 centrosomal protein 350kDa -0.016033
COL5A1 collagen, type V, alpha 1 -0.015934
EZR ezrin -0.0159003
TUBA1B tubulin, alpha 1b -0.0158671
BRI3BP BRI3 binding protein -0.0157084
PTGES3 prostaglandin E synthase 3 (cytosolic) -0.0156858
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2 -0.01568
ATRNL1 attractin-like 1 -0.0156628
CENPE centromere protein E, 312kDa -0.0156495
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -0.0156255
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -0.0155995
TNRC18 trinucleotide repeat containing 18 -0.0155849
COL4A5 collagen, type IV, alpha 5 -0.0154813
CYBA cytochrome b-245, alpha polypeptide -0.0154378
H2AC6 H2A clustered histone 6 -0.0154028
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 -0.0153833
TEX14 testis expressed 14 -0.0153539
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.015311
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 -0.0152912
SPATS2 spermatogenesis associated, serine-rich 2 -0.0152728
UBB ubiquitin B -0.0152385
NCAPG2 non-SMC condensin II complex, subunit G2 -0.0152016
PIAS1 protein inhibitor of activated STAT, 1 -0.0151783
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 -0.0150703
CREBBP CREB binding protein -0.0150668
CCDC170 coiled-coil domain containing 170 -0.0150603
SACK1B scaffolding CK1 anchoring protein B -0.0150508
SSH2 slingshot protein phosphatase 2 -0.0149466
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0149174
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) -0.0149173
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.0149142
FANCA Fanconi anemia, complementation group A -0.0148883
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 -0.014881
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -0.0148622
SSR1 signal sequence receptor, alpha -0.0148489
RAB10 RAB10, member RAS oncogene family -0.0147871
FIGN fidgetin -0.0147259
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0145684
PTTG1IP pituitary tumor-transforming 1 interacting protein -0.0145129
SRSF4 serine/arginine-rich splicing factor 4 -0.014511
PTGES2 prostaglandin E synthase 2 -0.0145065
SMG6 SMG6 nonsense mediated mRNA decay factor -0.0144708
PCLO piccolo presynaptic cytomatrix protein -0.0144118
SPOP speckle-type POZ protein -0.0143951
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -0.014344
NOTCH3 notch 3 -0.0142423
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 -0.0142263
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein -0.0142108
ZNF638 zinc finger protein 638 -0.0141893
ANLN anillin, actin binding protein -0.0141848
PDXK pyridoxal (pyridoxine, vitamin B6) kinase -0.0141293
DAAM1 dishevelled associated activator of morphogenesis 1 -0.0141038
GLCCI1 glucocorticoid induced 1 -0.0140485
UBE4B ubiquitination factor E4B -0.0139799
EMC10 ER membrane protein complex subunit 10 -0.0139702
SPOPL speckle-type POZ protein-like -0.0138921
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -0.0138784
ITGB4 integrin, beta 4 -0.0138523
NBEAL1 neurobeachin-like 1 -0.0138287
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 -0.0137801
TJP1 tight junction protein 1 -0.0137739
EPHA4 EPH receptor A4 -0.0136957
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -0.0136726
REEP5 receptor accessory protein 5 -0.0136519
USP37 ubiquitin specific peptidase 37 -0.0135934
TNRC6C trinucleotide repeat containing 6C -0.0135594
DNM2 dynamin 2 -0.0135568
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.0135475
STC1 stanniocalcin 1 -0.0135154
AGR3 anterior gradient 3 -0.0135092
TENM3 teneurin transmembrane protein 3 -0.0135048
ARSG arylsulfatase G -0.0135001
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.013495
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.0134927
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -0.0134825
BRCA2 breast cancer 2, early onset -0.0134742
HDLBP high density lipoprotein binding protein -0.0134704
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.0134302
TMEM131 transmembrane protein 131 -0.0134198
COPE coatomer protein complex, subunit epsilon -0.0133897
PCNT pericentrin -0.0133598
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -0.0133494
SMC4 structural maintenance of chromosomes 4 -0.0133391
SYTL4 synaptotagmin-like 4 -0.0133017
SPPL2A signal peptide peptidase like 2A -0.0132813
COL12A1 collagen, type XII, alpha 1 -0.0132603
LRP10 low density lipoprotein receptor-related protein 10 -0.01321
C21ORF58 chromosome 21 open reading frame 58 -0.0132048
WDFY3 WD repeat and FYVE domain containing 3 -0.0131636
UNK unkempt family zinc finger -0.0131361
KMT2A lysine (K)-specific methyltransferase 2A -0.0130479
NOL11 nucleolar protein 11 -0.0130436
H2BC5 H2B clustered histone 5 -0.0130089
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -0.0130044
WDR45 WD repeat domain 45 -0.0129779
MEPCE methylphosphate capping enzyme -0.0129772
CANX calnexin -0.0129486
MAN1A2 mannosidase, alpha, class 1A, member 2 -0.0128826
IGSF3 immunoglobulin superfamily, member 3 -0.012854
DCPH1 damage control phosphatase 1 -0.0128125
RPN2 ribophorin II -0.0127966
RTN3 reticulon 3 -0.0126973
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) -0.0126811
SKA2 spindle and kinetochore associated complex subunit 2 -0.0126058
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.0125935
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -0.0125789
ASTN2 astrotactin 2 -0.0125073
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.0124691
NPEPPS aminopeptidase puromycin sensitive -0.0124574
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L -0.0124517
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.0124499
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -0.0124172
NSD1 nuclear receptor binding SET domain protein 1 -0.0122517
GRHL2 grainyhead-like 2 (Drosophila) -0.0122512
MIDEAS mitotic deacetylase associated SANT domain protein -0.0122473
PLCB4 phospholipase C, beta 4 -0.0122417
CA4 carbonic anhydrase IV -0.0122256
LY6E lymphocyte antigen 6 complex, locus E -0.0122226
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 -0.0122204
TMCC1 transmembrane and coiled-coil domain family 1 -0.0122023
VKORC1 vitamin K epoxide reductase complex, subunit 1 -0.0121802
TRIM25 tripartite motif containing 25 -0.012027
JMJD1C jumonji domain containing 1C -0.0120052
GDI2 GDP dissociation inhibitor 2 -0.0119958
SSR4 signal sequence receptor, delta -0.0119934
MZT2B mitotic spindle organizing protein 2B -0.0119709
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.011944
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.0119424
BICD1 bicaudal D homolog 1 (Drosophila) -0.0118599
DSCAM Down syndrome cell adhesion molecule -0.0118367
TMEM184C transmembrane protein 184C -0.0118204
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin -0.0117907
CEP128 centrosomal protein 128kDa -0.0117772
GALC galactosylceramidase -0.0117655
DIAPH2 diaphanous-related formin 2 -0.0117635
NR4A1 nuclear receptor subfamily 4, group A, member 1 -0.0117514
TOM1L2 target of myb1-like 2 (chicken) -0.0117017
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) -0.0116921
H3C4 H3 clustered histone 4 -0.0116859
CFAP44 cilia and flagella associated protein 44 -0.0116641
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.0115649
MAP3K3 mitogen-activated protein kinase kinase kinase 3 -0.0115625
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.0115407
PLK2 polo-like kinase 2 -0.0115267
SELENOI selenoprotein I -0.0114725
KIF4A kinesin family member 4A -0.0114489
INO80 INO80 complex subunit -0.0114474
TSC22D1 TSC22 domain family, member 1 -0.0114096
SCARB2 scavenger receptor class B, member 2 -0.0114061
NVL nuclear VCP-like -0.0113923
AVEN apoptosis, caspase activation inhibitor -0.0113661
SKI SKI proto-oncogene -0.0113449
E2F7 E2F transcription factor 7 -0.0113434
PPP1R21 protein phosphatase 1, regulatory subunit 21 -0.0112974
THADA thyroid adenoma associated -0.011225
DOCK1 dedicator of cytokinesis 1 -0.0112118
TACC1 transforming, acidic coiled-coil containing protein 1 -0.0111817
FTSJ3 FtsJ homolog 3 (E. coli) -0.0111674
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.0111251
MMP16 matrix metallopeptidase 16 (membrane-inserted) -0.0110262
EPC2 enhancer of polycomb homolog 2 (Drosophila) -0.0110256
CPA6 carboxypeptidase A6 -0.0110022
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -0.0109961
MGST1 microsomal glutathione S-transferase 1 -0.0109135
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -0.0108913
SYNGR2 synaptogyrin 2 -0.0108891
TMPO thymopoietin -0.0108837
ARHGAP10 Rho GTPase activating protein 10 -0.0108298
ADARB1 adenosine deaminase, RNA-specific, B1 -0.0108195
TPX2 TPX2, microtubule-associated -0.0107645
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.0107642
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -0.010761
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0107337
PCNX4 pecanex 4 -0.0107134
GREB1L growth regulation by estrogen in breast cancer-like -0.010707
ANAPC16 anaphase promoting complex subunit 16 -0.0107068
KIF20B kinesin family member 20B -0.0106868
FRYL FRY-like -0.0106713
SOS1 son of sevenless homolog 1 (Drosophila) -0.0106587
RAB8A RAB8A, member RAS oncogene family -0.0106397
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -0.0106052
ICMT isoprenylcysteine carboxyl methyltransferase -0.0105845
CCNF cyclin F -0.0105793
NBEA neurobeachin -0.0105496
APRT adenine phosphoribosyltransferase -0.0105219
SOD2 superoxide dismutase 2, mitochondrial -0.0105086
SNX14 sorting nexin 14 -0.0104924
TMX1 thioredoxin-related transmembrane protein 1 -0.0104744
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.0104472
DOCK8 dedicator of cytokinesis 8 -0.0104393
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 -0.0104297
HELLS helicase, lymphoid-specific -0.0104247
CALR calreticulin -0.010412
KANSL1L KAT8 regulatory NSL complex subunit 1-like -0.010402
SCAMP2 secretory carrier membrane protein 2 -0.0103963
ELP2 elongator acetyltransferase complex subunit 2 -0.0103639
MAST2 microtubule associated serine/threonine kinase 2 -0.0103136
MAU2 MAU2 sister chromatid cohesion factor -0.0103125
SENP6 SUMO1/sentrin specific peptidase 6 -0.010294
H2BC8 H2B clustered histone 8 -0.0102911
PPP6R2 protein phosphatase 6, regulatory subunit 2 -0.0102869
LYPD6B LY6/PLAUR domain containing 6B -0.0102724
LDHA lactate dehydrogenase A -0.0102425
ATRX alpha thalassemia/mental retardation syndrome X-linked -0.0102266
ANKRD13C ankyrin repeat domain 13C -0.0102178
TBCA tubulin folding cofactor A -0.0101638
AIF1L allograft inflammatory factor 1-like -0.0101564
IDE insulin-degrading enzyme -0.0101156
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0101147
USP1 ubiquitin specific peptidase 1 -0.010103
H2AZ2 H2A.Z variant histone 2 -0.0100946
EPHA6 EPH receptor A6 -0.010066
PLEKHA6 pleckstrin homology domain containing, family A member 6 -0.0100581
CDC42SE2 CDC42 small effector 2 -0.0100391
TOP3A topoisomerase (DNA) III alpha -0.0100155
QKI QKI, KH domain containing, RNA binding -0.0100143
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b -0.0100047
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase -0.00999946
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00998086
GNAS GNAS complex locus -0.00997042
PATJ PATJ crumbs cell polarity complex component -0.00995258
JPT1 Jupiter microtubule associated homolog 1 -0.00994767
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -0.00993862
CTNNA3 catenin (cadherin-associated protein), alpha 3 -0.00993523
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle -0.0099128
BSG basigin (Ok blood group) -0.00985349
DLG1 discs, large homolog 1 (Drosophila) -0.00977003
DAD1 defender against cell death 1 -0.00976237
CENPN centromere protein N -0.00972163
CERT1 ceramide transporter 1 -0.00967867
SFPQ splicing factor proline/glutamine-rich -0.00965666
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -0.00963439
FCHSD2 FCH and double SH3 domains 2 -0.00961533
MECOM MDS1 and EVI1 complex locus -0.00961489
SGMS1 sphingomyelin synthase 1 -0.00961271
PLXNA4 plexin A4 -0.00960306
ST7L suppression of tumorigenicity 7 like -0.00958723
DHCR24 24-dehydrocholesterol reductase -0.00958686
ZNF804B zinc finger protein 804B -0.00958679
DGKH diacylglycerol kinase, eta -0.00954552
PGRMC1 progesterone receptor membrane component 1 -0.00954372
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 -0.00951637
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -0.00949706
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -0.00949395
ACLY ATP citrate lyase -0.00949375
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -0.00946895
GPER1 G protein-coupled estrogen receptor 1 -0.00944073
TK1 thymidine kinase 1, soluble -0.0094176
ENTREP1 endosomal transmembrane epsin interactor 1 -0.0093786
SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10 -0.00936224
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -0.00935774
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 -0.00933139
DIDO1 death inducer-obliterator 1 -0.00929344
THRAP3 thyroid hormone receptor associated protein 3 -0.00928646
RNF111 ring finger protein 111 -0.0092698
ZBTB4 zinc finger and BTB domain containing 4 -0.00926286
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 -0.00926266
SSBP3 single stranded DNA binding protein 3 -0.00924652
PBRM1 polybromo 1 -0.00919474
KIAA1549 KIAA1549 -0.00917889
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) -0.00917628
PLXNA3 plexin A3 -0.00916623
CDCA2 cell division cycle associated 2 -0.00914049
BCLAF1 BCL2-associated transcription factor 1 -0.00913913
FMN1 formin 1 -0.00910808
ARTN artemin -0.00908556
EP300 E1A binding protein p300 -0.00907047
NT5DC1 5'-nucleotidase domain containing 1 -0.00906858
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.00904367
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 -0.00904147
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -0.00904099
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00903378
DLG5 discs, large homolog 5 (Drosophila) -0.00902763
RRM2 ribonucleotide reductase M2 -0.00900304
PPP1R10 protein phosphatase 1, regulatory subunit 10 -0.00899597
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 -0.00899428
RANBP17 RAN binding protein 17 -0.00898565
KIF13A kinesin family member 13A -0.0089679
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -0.00894979
PHACTR2 phosphatase and actin regulator 2 -0.00894648
TRIM62 tripartite motif containing 62 -0.00894127
ATF5 activating transcription factor 5 -0.00890216
PHPT1 phosphohistidine phosphatase 1 -0.00889464
CAMK2G calcium/calmodulin-dependent protein kinase II gamma -0.00888369
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 -0.00888315
TM7SF2 transmembrane 7 superfamily member 2 -0.00888234
MPDU1 mannose-P-dolichol utilization defect 1 -0.00888022