MCF7_Valproic acid sodium salt_1µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description Valproic acid sodium salt 1µM perturbation in MCF7 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the MCF7_Valproic acid sodium salt_1µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
THSD4 thrombospondin, type I, domain containing 4 0.197078
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.15011
ESR1 estrogen receptor 1 0.120723
BCAS3 breast carcinoma amplified sequence 3 0.106358
ERBB4 erb-b2 receptor tyrosine kinase 4 0.104953
KRT18 keratin 18, type I 0.0971715
PARD6B par-6 family cell polarity regulator beta 0.0873368
MSI2 musashi RNA-binding protein 2 0.0858063
VMP1 vacuole membrane protein 1 0.0830467
IGFBP5 insulin-like growth factor binding protein 5 0.0827416
TRIM37 tripartite motif containing 37 0.0816368
UGDH UDP-glucose 6-dehydrogenase 0.0792502
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.077018
GREB1 growth regulation by estrogen in breast cancer 1 0.0727466
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0692617
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0669297
PLXDC2 plexin domain containing 2 0.0607001
BMAL2 basic helix-loop-helix ARNT like 2 0.0589007
MACROD2 MACRO domain containing 2 0.0578709
GNAS GNAS complex locus 0.0555724
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0523487
TET2 tet methylcytosine dioxygenase 2 0.0516454
PKM pyruvate kinase, muscle 0.0513956
SPTSSB serine palmitoyltransferase, small subunit B 0.0508367
UBL4A ubiquitin-like 4A 0.0504588
NCOA3 nuclear receptor coactivator 3 0.0481441
PRKCA protein kinase C, alpha 0.0477729
PTPRK protein tyrosine phosphatase, receptor type, K 0.0458412
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0451422
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 0.0450936
SMYD3 SET and MYND domain containing 3 0.0442579
MED13 mediator complex subunit 13 0.043898
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.0436312
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.0433945
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 0.0433338
MALRD1 MAM and LDL receptor class A domain containing 1 0.0419091
ELOF1 elongation factor 1 homolog (S. cerevisiae) 0.0411087
FGF12 fibroblast growth factor 12 0.0399092
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0386877
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.0382568
GREB1L growth regulation by estrogen in breast cancer-like 0.0374943
TMEM164 transmembrane protein 164 0.0371492
BASP1 brain abundant, membrane attached signal protein 1 0.0370672
CCND1 cyclin D1 0.0370301
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0361018
ENSA endosulfine alpha 0.0358914
PRRC2C proline-rich coiled-coil 2C 0.0353976
THRAP3 thyroid hormone receptor associated protein 3 0.0340304
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 0.0338701
XBP1 X-box binding protein 1 0.0332923
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 0.0328233
CCSER1 coiled-coil serine-rich protein 1 0.03201
COP1 COP1 E3 ubiquitin ligase 0.0316771
NCAM2 neural cell adhesion molecule 2 0.0311914
TOP1 topoisomerase (DNA) I 0.0304803
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 0.0299541
PLCB4 phospholipase C, beta 4 0.0297672
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.0296527
ZHX3 zinc fingers and homeoboxes 3 0.0292666
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.0292202
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 0.0290081
GOLGA4 golgin A4 0.0282691
CLTC clathrin, heavy chain (Hc) 0.0282662
BICD1 bicaudal D homolog 1 (Drosophila) 0.0281356
INVS inversin 0.0279977
LOC112694756 uncharaterized LOC112694756 0.0277284
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.0275953
SMIM14 small integral membrane protein 14 0.0275082
GATA3 GATA binding protein 3 0.0274954
MAPT microtubule-associated protein tau 0.0272656
UBE2R2 ubiquitin-conjugating enzyme E2R 2 0.0271762
ARHGAP12 Rho GTPase activating protein 12 0.027088
PTK2 protein tyrosine kinase 2 0.0264397
TTC3 tetratricopeptide repeat domain 3 0.026314
BPTF bromodomain PHD finger transcription factor 0.0262806
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 0.0261598
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.0261443
DIAPH1 diaphanous-related formin 1 0.0260972
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 0.0257738
PACS1 phosphofurin acidic cluster sorting protein 1 0.0256948
DTNA dystrobrevin, alpha 0.0254415
THOC2 THO complex 2 0.0251393
WNK1 WNK lysine deficient protein kinase 1 0.0251298
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.024989
SREBF1 sterol regulatory element binding transcription factor 1 0.0249771
IDE insulin-degrading enzyme 0.0247483
RTN4 reticulon 4 0.0246681
PTGES2 prostaglandin E synthase 2 0.0245326
TRAPPC9 trafficking protein particle complex 9 0.0243058
TAOK3 TAO kinase 3 0.0242466
ZFAND3 zinc finger, AN1-type domain 3 0.0242259
TEX14 testis expressed 14 0.0240759
EIF3I eukaryotic translation initiation factor 3, subunit I 0.0239683
ASCC3 activating signal cointegrator 1 complex subunit 3 0.0238446
VCP valosin containing protein 0.023778
EEIG1 estrogen-induced osteoclastogenesis regulator 1 0.0236443
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0236163
GSPT1 G1 to S phase transition 1 0.0235735
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 0.0235532
SOX4 SRY (sex determining region Y)-box 4 0.0235081
RHPN2 rhophilin, Rho GTPase binding protein 2 0.0234998
ZFR zinc finger RNA binding protein 0.0233804
MBD5 methyl-CpG binding domain protein 5 0.0233469
GLRA3 glycine receptor, alpha 3 0.0231924
SAMD1 sterile alpha motif domain containing 1 0.0230321
TIMP3 TIMP metallopeptidase inhibitor 3 0.0230224
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0229235
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.0226615
GATAD2B GATA zinc finger domain containing 2B 0.0226558
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 0.0225899
SENP5 SUMO1/sentrin specific peptidase 5 0.0224761
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0223809
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 0.0223754
SETD2 SET domain containing 2 0.0221578
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.0221203
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 0.0217911
MAPKAP1 mitogen-activated protein kinase associated protein 1 0.0217444
KDM4A lysine (K)-specific demethylase 4A 0.0217225
MYOF myoferlin 0.0217042
CAMKMT calmodulin-lysine N-methyltransferase 0.0216424
DCLK1 doublecortin-like kinase 1 0.0216259
ZMYND11 zinc finger, MYND-type containing 11 0.0216218
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.0215858
RPL15 ribosomal protein L15 0.0215474
RPS5 ribosomal protein S5 0.0215006
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor 0.0214321
RPL9 ribosomal protein L9 0.0213256
ARHGAP5 Rho GTPase activating protein 5 0.0213065
GON4L gon-4-like (C. elegans) 0.0211591
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 0.0211522
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.021126
LARP4 La ribonucleoprotein domain family, member 4 0.0211217
KRT19 keratin 19, type I 0.021049
TPR translocated promoter region, nuclear basket protein 0.0210254
CFAP161 cilia and flagella associated protein 161 0.0210224
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.0209754
SEC24B SEC24 family member B 0.0209667
ZMYM4 zinc finger, MYM-type 4 0.020908
LSG1 large 60S subunit nuclear export GTPase 1 0.0209051
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 0.0207989
PCDHB16 protocadherin beta 16 0.0207323
BIRC6 baculoviral IAP repeat containing 6 0.0206392
SLC35E3 solute carrier family 35, member E3 0.020629
ECD ecdysoneless homolog (Drosophila) 0.0205604
MAP2K2 mitogen-activated protein kinase kinase 2 0.0205349
ABAT 4-aminobutyrate aminotransferase 0.0205325
ZFPM1 zinc finger protein, FOG family member 1 0.0204733
SEPTIN9 septin 9 0.0203649
RGS6 regulator of G-protein signaling 6 0.0202609
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 0.0202023
SEC31A SEC31 homolog A (S. cerevisiae) 0.0200505
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 0.0200092
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.0200057
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.0199538
UBA6 ubiquitin-like modifier activating enzyme 6 0.0199172
ACTG1 actin gamma 1 0.0198983
PGR progesterone receptor 0.0197562
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 0.0197286
GSK3B glycogen synthase kinase 3 beta 0.0197014
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 0.0196574
EP300 E1A binding protein p300 0.0195607
ATXN1 ataxin 1 0.0195514
DSCAM Down syndrome cell adhesion molecule 0.0195386
HMGB1 high mobility group box 1 0.0193895
PTBP3 polypyrimidine tract binding protein 3 0.0193856
EEF2 eukaryotic translation elongation factor 2 0.0193751
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 0.019314
ZNF236 zinc finger protein 236 0.0192643
TBC1D32 TBC1 domain family, member 32 0.0192341
LAMA5 laminin, alpha 5 0.0192313
CERCAM cerebral endothelial cell adhesion molecule 0.0191582
RNF19B ring finger protein 19B 0.0191429
NAP1L4 nucleosome assembly protein 1-like 4 0.0191304
RHOBTB3 Rho-related BTB domain containing 3 0.0191089
KHSRP KH-type splicing regulatory protein 0.0190294
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.0190022
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 0.0189876
CLU clusterin 0.0188947
FAF1 Fas (TNFRSF6) associated factor 1 0.0188902
MRPS23 mitochondrial ribosomal protein S23 0.0188713
DEK DEK proto-oncogene 0.0187927
STX16 syntaxin 16 0.0186681
ITSN1 intersectin 1 (SH3 domain protein) 0.018627
CLTA clathrin, light chain A 0.0185607
CHD1 chromodomain helicase DNA binding protein 1 0.0185401
TUBA1C tubulin, alpha 1c 0.0185385
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 0.0184996
CST3 cystatin C 0.0184182
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 0.0182709
PAPOLA poly(A) polymerase alpha 0.0182376
CCDC142 coiled-coil domain containing 142 0.0181638
FAM120A family with sequence similarity 120A 0.0181542
CENPF centromere protein F, 350/400kDa 0.0181488
TRAPPC10 trafficking protein particle complex 10 0.018146
CDYL2 chromodomain protein, Y-like 2 0.0181028
KMT2C lysine (K)-specific methyltransferase 2C 0.0180169
PEBP1 phosphatidylethanolamine binding protein 1 0.0179855
RHOC ras homolog family member C 0.0179076
NCOR1 nuclear receptor corepressor 1 0.0178547
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0178367
DHCR7 7-dehydrocholesterol reductase 0.0178234
SQLE squalene epoxidase 0.0177661
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.0177588
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 0.0176825
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 0.017679
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.017634
LTBP1 latent transforming growth factor beta binding protein 1 0.0176284
TMEM117 transmembrane protein 117 0.0176011
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.0175537
RARA retinoic acid receptor, alpha 0.0175335
CCDC6 coiled-coil domain containing 6 0.0174642
PLD3 phospholipase D family, member 3 0.0174537
DUSP16 dual specificity phosphatase 16 0.017438
GAB2 GRB2-associated binding protein 2 0.0174261
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.0174226
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.0174079
C14ORF132 chromosome 14 open reading frame 132 0.0173935
RAD23B RAD23 homolog B (S. cerevisiae) 0.0173924
IARS1 isoleucyl-tRNA synthetase 1 0.0173632
ZYG11B zyg-11 family member B, cell cycle regulator 0.0172857
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.0172713
ITFG1 integrin alpha FG-GAP repeat containing 1 0.0172235
HSDL2 hydroxysteroid dehydrogenase like 2 0.0170784
TOM1L1 target of myb1 (chicken)-like 1 0.0170764
UBE3B ubiquitin protein ligase E3B 0.0170731
RBM15 RNA binding motif protein 15 0.0170468
PCCA propionyl CoA carboxylase, alpha polypeptide 0.0169932
TTC17 tetratricopeptide repeat domain 17 0.0169503
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.0168392
ZNF516 zinc finger protein 516 0.0167597
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 0.0167403
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.016718
SFSWAP splicing factor, suppressor of white-apricot family 0.01668
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.0166707
XPR1 xenotropic and polytropic retrovirus receptor 1 0.0166645
FGD4 FYVE, RhoGEF and PH domain containing 4 0.0166544
RPL6 ribosomal protein L6 0.0166413
NCK1 NCK adaptor protein 1 0.0166014
ATP13A3 ATPase type 13A3 0.0165826
USP34 ubiquitin specific peptidase 34 0.0165688
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 0.0165684
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.0165599
PSME4 proteasome (prosome, macropain) activator subunit 4 0.0165508
KPNA1 karyopherin alpha 1 (importin alpha 5) 0.0165327
CUL2 cullin 2 0.01649
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 0.0164586
VIRMA vir like m6A methyltransferase associated 0.0163883
SUCO SUN domain containing ossification factor 0.0163682
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.0163574
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 0.0163491
TXNRD1 thioredoxin reductase 1 0.0162918
DMXL2 Dmx-like 2 0.0162897
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 0.0162622
TET3 tet methylcytosine dioxygenase 3 0.0162121
FIGN fidgetin 0.0162048
KMT2A lysine (K)-specific methyltransferase 2A 0.016198
GARNL3 GTPase activating Rap/RanGAP domain-like 3 0.0161082
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) 0.0160095
PFN1 profilin 1 0.0160032
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 0.0159964
KRT80 keratin 80, type II 0.015941
CYTH3 cytohesin 3 0.0159317
KCTD3 potassium channel tetramerization domain containing 3 0.0159082
VEZT vezatin, adherens junctions transmembrane protein 0.0158852
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.015865
C1ORF21 chromosome 1 open reading frame 21 0.0157913
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.0157838
SRSF11 serine/arginine-rich splicing factor 11 0.0156964
YME1L1 YME1-like 1 ATPase 0.0155689
TMEM64 transmembrane protein 64 0.0155659
SLC38A9 solute carrier family 38, member 9 0.0155185
FAM168A family with sequence similarity 168, member A 0.0154808
MUSK muscle, skeletal, receptor tyrosine kinase 0.0154217
MIA2 melanoma inhibitory activity 2 0.015407
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 0.0153049
ZCCHC8 zinc finger, CCHC domain containing 8 0.0153028
JAK2 Janus kinase 2 0.0152869
TKT transketolase 0.0152811
SGMS1 sphingomyelin synthase 1 0.0152562
SCRN1 secernin 1 0.0152197
NOL9 nucleolar protein 9 0.0152075
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 0.0152065
ZNF787 zinc finger protein 787 0.0151767
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.0151675
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0151591
NRF1 nuclear respiratory factor 1 0.015152
CENPE centromere protein E, 312kDa 0.0151426
SHARPIN SHANK-associated RH domain interactor 0.0150635
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0149828
KRTAP11-1 keratin associated protein 11-1 0.0149192
FKBP15 FK506 binding protein 15, 133kDa 0.0148889
LGALS12 lectin, galactoside-binding, soluble, 12 0.0148828
ADGRG1 adhesion G protein-coupled receptor G1 0.0148129
FAF2 Fas associated factor family member 2 0.0147972
SLC35F5 solute carrier family 35, member F5 0.0147536
CDC42SE1 CDC42 small effector 1 0.0147199
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 0.0146945
SORT1 sortilin 1 0.0146913
EMC3 ER membrane protein complex subunit 3 0.0146567
GORASP2 golgi reassembly stacking protein 2, 55kDa 0.0146565
ZNF407 zinc finger protein 407 0.0146518
RAB29 RAB29, member RAS oncogene family 0.0146517
TXN2 thioredoxin 2 0.0146384
NHSL1 NHS-like 1 0.0146356
USP1 ubiquitin specific peptidase 1 0.0146084
MIA3 melanoma inhibitory activity family, member 3 0.0145991
NOCT nocturnin 0.0145562
FUS FUS RNA binding protein 0.0144916
FAM120AOS family with sequence similarity 120A opposite strand 0.0144767
DTNB dystrobrevin, beta 0.014393
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) 0.014378
PTRH2 peptidyl-tRNA hydrolase 2 0.0143726
KTN1 kinectin 1 (kinesin receptor) 0.0143717
NUDCD1 NudC domain containing 1 0.014371
SAMD12 sterile alpha motif domain containing 12 0.0143591
PSD3 pleckstrin and Sec7 domain containing 3 0.0143068
ITFG2 integrin alpha FG-GAP repeat containing 2 0.0142904
PHACTR4 phosphatase and actin regulator 4 0.0142801
SATB2 SATB homeobox 2 0.0142652
GSTM3 glutathione S-transferase mu 3 (brain) 0.0142582
DPEP2 dipeptidase 2 0.0142478
KIF5B kinesin family member 5B 0.0142434
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.014165
MAN1A2 mannosidase, alpha, class 1A, member 2 0.0141633
MRPL9 mitochondrial ribosomal protein L9 0.0141242
GMPS guanine monphosphate synthase 0.0140882
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0140788
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 0.0140427
EPN2 epsin 2 0.0140415
GPBP1L1 GC-rich promoter binding protein 1-like 1 0.014017
RPL12 ribosomal protein L12 0.0140102
NUP85 nucleoporin 85kDa 0.0140011
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.0139836
HS3ST5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5 0.0139789
ZDHHC17 zinc finger, DHHC-type containing 17 0.0139466
STARD13 StAR-related lipid transfer (START) domain containing 13 0.01393
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 0.0139196
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.0139187
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.0139116
SP3 Sp3 transcription factor 0.0139019
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 0.0139016
ERCC2 excision repair cross-complementation group 2 0.0138763
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0138191
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.0138012
SND1 staphylococcal nuclease and tudor domain containing 1 0.0137656
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.0137591
SRGAP2B SLIT-ROBO Rho GTPase activating protein 2B 0.0137581
EPC1 enhancer of polycomb homolog 1 (Drosophila) 0.0137401
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 0.0137377
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.0137368
TNRC6C trinucleotide repeat containing 6C 0.013736
SRPK2 SRSF protein kinase 2 0.0137287
ZNF33A zinc finger protein 33A 0.0137282
BRD2 bromodomain containing 2 0.0136931
DOCK1 dedicator of cytokinesis 1 0.0136875
PTMA prothymosin, alpha 0.0136757
STARD7 StAR-related lipid transfer (START) domain containing 7 0.0136679
PDE8A phosphodiesterase 8A 0.0136662
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing 0.0136458
AP3D1 adaptor-related protein complex 3, delta 1 subunit 0.0135925
ATP5F1B ATP synthase F1 subunit beta 0.0135775
RGS17 regulator of G-protein signaling 17 0.0135504
JAK1 Janus kinase 1 0.0135402
LPGAT1 lysophosphatidylglycerol acyltransferase 1 0.0135305
UBXN4 UBX domain protein 4 0.0135273
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.0135245
SERF2 small EDRK-rich factor 2 0.0135122
ZDHHC20 zinc finger, DHHC-type containing 20 0.013502
SHTN1 shootin 1 0.0134684
SEPHS2 selenophosphate synthetase 2 0.0134648
LAPTM4B lysosomal protein transmembrane 4 beta 0.0134636
MYL12B myosin, light chain 12B, regulatory 0.0134513
PDIA3 protein disulfide isomerase family A, member 3 0.0134464
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.0133514
IFT43 intraflagellar transport 43 0.0133379
ZRANB3 zinc finger, RAN-binding domain containing 3 0.0133246
OPHN1 oligophrenin 1 0.0133213
LAMP1 lysosomal-associated membrane protein 1 0.0133127
SFXN5 sideroflexin 5 0.013312
TLE3 transducin-like enhancer of split 3 0.0132765
MREG melanoregulin 0.0132707
FMNL2 formin-like 2 0.0132375
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.0131758
EMCN endomucin 0.0131652
MAVS mitochondrial antiviral signaling protein 0.013161
QPCTL glutaminyl-peptide cyclotransferase-like 0.0131573
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.013149
SEC16A SEC16 homolog A (S. cerevisiae) 0.0131154
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 0.0131119
TANGO6 transport and golgi organization 6 homolog (Drosophila) 0.0130914
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.0130806
UST uronyl-2-sulfotransferase 0.0130762
BAG3 BCL2-associated athanogene 3 0.0130367
ALMS1 Alstrom syndrome protein 1 0.0130346
SPPL3 signal peptide peptidase like 3 0.0130323
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.0130312
INIP INTS3 and NABP interacting protein 0.0129991
APOD apolipoprotein D 0.0129989
PHKG2 phosphorylase kinase, gamma 2 (testis) 0.0129821
PLS1 plastin 1 0.0129818
HSPB1 heat shock 27kDa protein 1 0.012968
PURA purine-rich element binding protein A 0.0129464
CD44 CD44 molecule (Indian blood group) 0.0129029
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.0128989
TTC8 tetratricopeptide repeat domain 8 0.0128862
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.012885
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 0.0128697
BRD3 bromodomain containing 3 0.0128655
SAR1A secretion associated, Ras related GTPase 1A 0.0128625
COX20 COX20 cytochrome c oxidase assembly factor 0.0128609
TMEM184A transmembrane protein 184A 0.012847
PHC3 polyhomeotic homolog 3 (Drosophila) 0.0127907
INO80D INO80 complex subunit D 0.0127596
SNX13 sorting nexin 13 0.0127535
PRPF6 pre-mRNA processing factor 6 0.0127496
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 0.0126924
FBXO22 F-box protein 22 0.0126793
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.0126327
GPS1 G protein pathway suppressor 1 0.012581
MAPK14 mitogen-activated protein kinase 14 0.0125729
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa 0.012565
HIBCH 3-hydroxyisobutyryl-CoA hydrolase 0.0125592
DPP7 dipeptidyl-peptidase 7 0.0125379
TSLIG1 tRNA splicing ligase complex subunit 1 0.0125212
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0125098
NCOA6 nuclear receptor coactivator 6 0.0125062
TBL1X transducin (beta)-like 1X-linked 0.0124863
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 0.0124807
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 0.0124632
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.0124434
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 0.0124261
DST dystonin 0.0124158
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.0123795
RPL7L1 ribosomal protein L7-like 1 0.0123775
COL5A1 collagen, type V, alpha 1 0.0123695
PCSK2 proprotein convertase subtilisin/kexin type 2 0.012341
NIPAL2 NIPA-like domain containing 2 0.0123076
ANXA7 annexin A7 0.0123044
HACD1 3-hydroxyacyl-CoA dehydratase 1 0.0122991
MYO5A myosin VA (heavy chain 12, myoxin) 0.0122929
CEP104 centrosomal protein 104kDa 0.0122893
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit 0.0122861
MYO1E myosin IE 0.0122715
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) 0.0122401
PLEKHJ1 pleckstrin homology domain containing, family J member 1 0.0122212
CTBP2 C-terminal binding protein 2 0.0122123
GPHRA golgi pH regulator A 0.0122121
CD46 CD46 molecule, complement regulatory protein 0.0121826
ITGB5 integrin, beta 5 0.0121622
TFDP1 transcription factor Dp-1 0.0121468
LRRC69 leucine rich repeat containing 69 0.0120839
VAMP8 vesicle-associated membrane protein 8 0.0120619
UBFD1 ubiquitin family domain containing 1 0.0120567
PDIA5 protein disulfide isomerase family A, member 5 0.0120557
GNB5 guanine nucleotide binding protein (G protein), beta 5 0.0120509
GNA14 guanine nucleotide binding protein (G protein), alpha 14 0.0120392
ZFHX3 zinc finger homeobox 3 0.012037
PCF11 PCF11 cleavage and polyadenylation factor subunit 0.0120325
BAG1 BCL2-associated athanogene 0.0120232
LNPEP leucyl/cystinyl aminopeptidase 0.0120203
ATF5 activating transcription factor 5 0.011985
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.0119613
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.0119556
MAPK6 mitogen-activated protein kinase 6 0.0119479
XPO4 exportin 4 0.011941
SACS sacsin molecular chaperone 0.0119229
KIAA0319L KIAA0319-like 0.011901
OSGIN2 oxidative stress induced growth inhibitor family member 2 0.0118842
METTL16 methyltransferase like 16 0.0118808
RAMP3 receptor (G protein-coupled) activity modifying protein 3 0.0118805
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0118788
NUP160 nucleoporin 160kDa 0.0118783
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 0.0118765
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.0118756
CSNK2A2 casein kinase 2, alpha prime polypeptide 0.0118629
ANKRD36C ankyrin repeat domain 36C 0.0118619
EXOSC10 exosome component 10 0.0118603
TPM4 tropomyosin 4 0.0118474
TMEM131 transmembrane protein 131 0.0118384
DPP8 dipeptidyl-peptidase 8 0.0118201
SLC30A6 solute carrier family 30 (zinc transporter), member 6 0.0118152
RASAL2 RAS protein activator like 2 0.0118122
TCEAL4 transcription elongation factor A (SII)-like 4 0.0117507
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 0.0117311
PTBP1 polypyrimidine tract binding protein 1 0.0117289
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.0117072
ZNF394 zinc finger protein 394 0.0116976
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 0.0116871
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 0.0116826
TMEM120A transmembrane protein 120A 0.0116684
MRPS21 mitochondrial ribosomal protein S21 0.0116675
ZNF440 zinc finger protein 440 0.0116594
CADM1 cell adhesion molecule 1 0.0116471
FYCO1 FYVE and coiled-coil domain containing 1 0.0116404
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.0116327
PRXL2A peroxiredoxin like 2A 0.0116289
TRIM25 tripartite motif containing 25 0.0116176
ZC3H7B zinc finger CCCH-type containing 7B 0.0116112
ING5 inhibitor of growth family, member 5 0.0116088
GSTK1 glutathione S-transferase kappa 1 0.0115869

decreased expression

Symbol Name Standardized Value
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.184574
IFI6 interferon, alpha-inducible protein 6 -0.151021
RPL30 ribosomal protein L30 -0.109341
TFF1 trefoil factor 1 -0.102787
AGR2 anterior gradient 2 -0.0964815
EVL Enah/Vasp-like -0.0924653
LRP1B low density lipoprotein receptor-related protein 1B -0.0884081
RPL28 ribosomal protein L28 -0.0822813
BSG basigin (Ok blood group) -0.0809542
PAWR PRKC, apoptosis, WT1, regulator -0.079124
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0730995
SYTL2 synaptotagmin-like 2 -0.0676861
RPLP1 ribosomal protein, large, P1 -0.0675692
BMP7 bone morphogenetic protein 7 -0.0648051
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.0639796
SDK1 sidekick cell adhesion molecule 1 -0.0638057
RPS3 ribosomal protein S3 -0.0623564
RPS29 ribosomal protein S29 -0.0577005
MRPL13 mitochondrial ribosomal protein L13 -0.0562621
GFRA1 GDNF family receptor alpha 1 -0.0560355
RPLP0 ribosomal protein, large, P0 -0.0554642
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.0543693
NPAS3 neuronal PAS domain protein 3 -0.0531412
NEBL nebulette -0.0509416
WWOX WW domain containing oxidoreductase -0.0509405
CALR calreticulin -0.0504797
ENO1 enolase 1, (alpha) -0.047652
STK24 serine/threonine kinase 24 -0.0456246
RPS19 ribosomal protein S19 -0.0437267
UBE3C ubiquitin protein ligase E3C -0.0426836
RPS2 ribosomal protein S2 -0.04235
RPLP2 ribosomal protein, large, P2 -0.0417067
KDM5B lysine (K)-specific demethylase 5B -0.0414511
ATAD2 ATPase family, AAA domain containing 2 -0.0408831
RPL32 ribosomal protein L32 -0.0401947
RPL37A ribosomal protein L37a -0.0400592
DSPP dentin sialophosphoprotein -0.0398242
IRS1 insulin receptor substrate 1 -0.0394373
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 -0.0391565
LY6E lymphocyte antigen 6 complex, locus E -0.0388997
NRIP1 nuclear receptor interacting protein 1 -0.0388913
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0388898
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.0375932
PHF14 PHD finger protein 14 -0.037533
ATXN7 ataxin 7 -0.0373662
FANCA Fanconi anemia, complementation group A -0.0372832
ITGB4 integrin, beta 4 -0.037187
FOXO3 forkhead box O3 -0.0370527
SKA2 spindle and kinetochore associated complex subunit 2 -0.0370205
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.0368927
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein -0.0365781
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0365622
CTSD cathepsin D -0.0362691
RPS12 ribosomal protein S12 -0.035972
UBE2H ubiquitin-conjugating enzyme E2H -0.0354778
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0353128
MYH9 myosin, heavy chain 9, non-muscle -0.0352652
FOXP1 forkhead box P1 -0.0351098
CYRIB CYFIP related Rac1 interactor B -0.0351
MRTFA myocardin related transcription factor A -0.035024
ZMYM2 zinc finger, MYM-type 2 -0.03486
RPL8 ribosomal protein L8 -0.0347254
ATP9A ATPase, class II, type 9A -0.0344777
EMP2 epithelial membrane protein 2 -0.0342551
MEF2A myocyte enhancer factor 2A -0.0341029
CTNND2 catenin (cadherin-associated protein), delta 2 -0.0339888
RPS14 ribosomal protein S14 -0.0338085
FBXL17 F-box and leucine-rich repeat protein 17 -0.033242
CD81 CD81 molecule -0.0332386
ADIPOR2 adiponectin receptor 2 -0.0332131
MKI67 marker of proliferation Ki-67 -0.0326296
PRRC2B proline-rich coiled-coil 2B -0.032507
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -0.0323926
MTSS1 metastasis suppressor 1 -0.0321648
TMEM150C transmembrane protein 150C -0.0320997
CSDE1 cold shock domain containing E1, RNA-binding -0.0320963
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0320602
CLIC4 chloride intracellular channel 4 -0.0319009
SYCP2 synaptonemal complex protein 2 -0.031874
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0318477
TRIM33 tripartite motif containing 33 -0.0317924
NUMA1 nuclear mitotic apparatus protein 1 -0.0316109
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 -0.03142
CDK6 cyclin-dependent kinase 6 -0.0311786
NECAB1 N-terminal EF-hand calcium binding protein 1 -0.0311236
SERINC3 serine incorporator 3 -0.0303419
TAPBP TAP binding protein (tapasin) -0.0301811
TENM3 teneurin transmembrane protein 3 -0.030134
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -0.0301208
H3-3B H3.3 histone B -0.0300431
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.0299927
RPS21 ribosomal protein S21 -0.029814
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.0296981
RPS11 ribosomal protein S11 -0.0295914
AFF4 AF4/FMR2 family, member 4 -0.0295192
SHANK2 SH3 and multiple ankyrin repeat domains 2 -0.0294932
NFX1 nuclear transcription factor, X-box binding 1 -0.0287356
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0287149
THOC7 THO complex 7 -0.0284869
JARID2 jumonji, AT rich interactive domain 2 -0.0281219
ANAPC16 anaphase promoting complex subunit 16 -0.0280386
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0278699
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -0.0277122
USP9X ubiquitin specific peptidase 9, X-linked -0.0276811
BTBD9 BTB (POZ) domain containing 9 -0.0270392
LCOR ligand dependent nuclear receptor corepressor -0.0269812
SERINC5 serine incorporator 5 -0.0267123
ABR active BCR-related -0.0266391
MAML3 mastermind-like 3 (Drosophila) -0.0266352
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0265543
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -0.0264791
MACC1 metastasis associated in colon cancer 1 -0.0263044
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 -0.0262553
MRTFB myocardin related transcription factor B -0.0262208
GOLM2 golgi membrane protein 2 -0.0259438
IQANK1 IQ motif and ankyrin repeat containing 1 -0.0259084
ZNF217 zinc finger protein 217 -0.0258967
HMCN1 hemicentin 1 -0.0258725
KDM2A lysine (K)-specific demethylase 2A -0.0257835
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.0257827
FGF13 fibroblast growth factor 13 -0.0257737
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.0257128
CD164 CD164 molecule, sialomucin -0.0256689
MCM4 minichromosome maintenance complex component 4 -0.0254927
RPS9 ribosomal protein S9 -0.0254905
RPL29 ribosomal protein L29 -0.0254163
MAP4 microtubule-associated protein 4 -0.0253756
CHLSN cholesin -0.0252907
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0251952
MAP7 microtubule-associated protein 7 -0.0251909
PPP4R3A protein phosphatase 4 regulatory subunit 3A -0.0249598
SSR4 signal sequence receptor, delta -0.0249234
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 -0.0248858
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -0.0247692
EPHA4 EPH receptor A4 -0.0245723
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.0244116
RPL38 ribosomal protein L38 -0.0243156
SCD5 stearoyl-CoA desaturase 5 -0.0242378
MED13L mediator complex subunit 13-like -0.0239317
ARPP19 cAMP-regulated phosphoprotein, 19kDa -0.0238828
TCF12 transcription factor 12 -0.0238596
RAD9A RAD9 homolog A (S. pombe) -0.0237667
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.0237263
SACK1B scaffolding CK1 anchoring protein B -0.0234542
TPT1 tumor protein, translationally-controlled 1 -0.0232899
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed -0.023254
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 -0.0232105
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -0.0231169
EPCAM epithelial cell adhesion molecule -0.0231094
SIN3A SIN3 transcription regulator family member A -0.0230724
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.0230554
TPD52 tumor protein D52 -0.022962
NRP1 neuropilin 1 -0.022885
RPL10A ribosomal protein L10a -0.0228433
GPSM2 G-protein signaling modulator 2 -0.0228169
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 -0.0227718
HP1BP3 heterochromatin protein 1, binding protein 3 -0.0227081
LRP10 low density lipoprotein receptor-related protein 10 -0.0226567
RPL18 ribosomal protein L18 -0.0225201
ZMYND8 zinc finger, MYND-type containing 8 -0.0224286
UTRN utrophin -0.0224035
CLSTN1 calsyntenin 1 -0.0223074
RPSA ribosomal protein SA -0.0222903
UBP1 upstream binding protein 1 (LBP-1a) -0.0222669
TJP1 tight junction protein 1 -0.022183
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.022115
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0220886
HDGFL3 HDGF like 3 -0.0220832
CLASP1 cytoplasmic linker associated protein 1 -0.0219821
CREB1 cAMP responsive element binding protein 1 -0.0219601
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0219037
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.021886
ZDHHC12 zinc finger, DHHC-type containing 12 -0.0218517
COX4I1 cytochrome c oxidase subunit IV isoform 1 -0.0218303
THADA thyroid adenoma associated -0.0217597
VCL vinculin -0.0217208
DLC1 DLC1 Rho GTPase activating protein -0.0216679
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) -0.0216347
ARID4A AT rich interactive domain 4A (RBP1-like) -0.0216215
ATP5F1E ATP synthase F1 subunit epsilon -0.0216192
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -0.0216071
KAT6B K(lysine) acetyltransferase 6B -0.0214947
BRCA1 breast cancer 1, early onset -0.021461
KDM5A lysine (K)-specific demethylase 5A -0.0213538
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -0.0213201
CLPTM1 cleft lip and palate associated transmembrane protein 1 -0.0213193
MTDH metadherin -0.0211981
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha -0.0211071
CD151 CD151 molecule (Raph blood group) -0.0210754
UBTF upstream binding transcription factor, RNA polymerase I -0.0210347
PAN3 PAN3 poly(A) specific ribonuclease subunit -0.0209454
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -0.0208714
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -0.0208382
BLTP1 bridge-like lipid transfer protein family member 1 -0.0207293
FXYD3 FXYD domain containing ion transport regulator 3 -0.0207154
UBA2 ubiquitin-like modifier activating enzyme 2 -0.0206702
NECTIN2 nectin cell adhesion molecule 2 -0.0205651
GNPDA1 glucosamine-6-phosphate deaminase 1 -0.0205634
ARL8B ADP-ribosylation factor-like 8B -0.0205069
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle -0.0205014
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -0.0204911
RPL34 ribosomal protein L34 -0.0203911
MYO5C myosin VC -0.0203503
VGLL4 vestigial-like family member 4 -0.0202297
ESYT1 extended synaptotagmin-like protein 1 -0.020124
GALC galactosylceramidase -0.0201036
CBX5 chromobox homolog 5 -0.0199894
ACTN4 actinin, alpha 4 -0.01992
PTTG1IP pituitary tumor-transforming 1 interacting protein -0.0198706
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.0198592
GTF2I general transcription factor IIi -0.0196607
IFITM3 interferon induced transmembrane protein 3 -0.0195851
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -0.0195548
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -0.0195059
LGALS3 lectin, galactoside-binding, soluble, 3 -0.0194921
PPP6R3 protein phosphatase 6, regulatory subunit 3 -0.0194875
CDK13 cyclin-dependent kinase 13 -0.0193573
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 -0.0193439
TMEM245 transmembrane protein 245 -0.0193141
PIAS1 protein inhibitor of activated STAT, 1 -0.0193071
RYBP RING1 and YY1 binding protein -0.0192905
SCMH1 sex comb on midleg homolog 1 (Drosophila) -0.0192871
PATJ PATJ crumbs cell polarity complex component -0.0191779
ZBTB7A zinc finger and BTB domain containing 7A -0.0191597
FAM174B family with sequence similarity 174, member B -0.0191491
NCAPD2 non-SMC condensin I complex, subunit D2 -0.0191439
AGO2 argonaute RISC catalytic component 2 -0.0191224
TTC19 tetratricopeptide repeat domain 19 -0.0190563
SCAF8 SR-related CTD-associated factor 8 -0.0190471
ACYP2 acylphosphatase 2, muscle type -0.0190187
WASF2 WAS protein family, member 2 -0.018968
EEA1 early endosome antigen 1 -0.018958
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -0.0188776
CD58 CD58 molecule -0.0188693
FBP1 fructose-1,6-bisphosphatase 1 -0.0188527
SVIL supervillin -0.018835
SPPL2A signal peptide peptidase like 2A -0.0187553
ZNF292 zinc finger protein 292 -0.0187518
SULF2 sulfatase 2 -0.018702
RUFY2 RUN and FYVE domain containing 2 -0.0186056
MARVELD2 MARVEL domain containing 2 -0.0185956
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0185189
RNF130 ring finger protein 130 -0.0184648
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 -0.0184432
MCM3AP minichromosome maintenance complex component 3 associated protein -0.0184327
PHB2 prohibitin 2 -0.0184121
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 -0.0183774
RPS15 ribosomal protein S15 -0.0183641
TRIP11 thyroid hormone receptor interactor 11 -0.0183566
TGFB2 transforming growth factor, beta 2 -0.0183021
TTLL10 tubulin tyrosine ligase-like family member 10 -0.018247
ADARB1 adenosine deaminase, RNA-specific, B1 -0.0181972
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 -0.0181568
HIBADH 3-hydroxyisobutyrate dehydrogenase -0.0181396
EIF2A eukaryotic translation initiation factor 2A, 65kDa -0.0181083
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.018106
H2AZ2 H2A.Z variant histone 2 -0.0181042
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0180812
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -0.0179808
DSTN destrin (actin depolymerizing factor) -0.0179704
ANKFY1 ankyrin repeat and FYVE domain containing 1 -0.0179277
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0179195
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 -0.0179108
MBTPS1 membrane-bound transcription factor peptidase, site 1 -0.0178988
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -0.0178932
RPL31 ribosomal protein L31 -0.0177899
NSD2 nuclear receptor binding SET domain protein 2 -0.0177669
COG8 component of oligomeric golgi complex 8 -0.0177334
BCAS1 breast carcinoma amplified sequence 1 -0.0177126
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.0177065
PLEKHA6 pleckstrin homology domain containing, family A member 6 -0.017705
SYNGR2 synaptogyrin 2 -0.0176877
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0176497
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -0.0175535
TMX1 thioredoxin-related transmembrane protein 1 -0.0175446
KIAA1958 KIAA1958 -0.01754
PRC1 protein regulator of cytokinesis 1 -0.0175297
QKI QKI, KH domain containing, RNA binding -0.0175243
PRIM2 primase, DNA, polypeptide 2 (58kDa) -0.0174839
HOMER2 homer scaffolding protein 2 -0.0174677
GAN gigaxonin -0.0174173
TNRC6A trinucleotide repeat containing 6A -0.0173889
TPM3 tropomyosin 3 -0.0173487
CAPZB capping protein (actin filament) muscle Z-line, beta -0.0173301
KCTD13 potassium channel tetramerization domain containing 13 -0.0173129
STAG2 stromal antigen 2 -0.0172685
FAM13B family with sequence similarity 13, member B -0.0172117
ATP5MG ATP synthase membrane subunit g -0.0171125
PIGM phosphatidylinositol glycan anchor biosynthesis, class M -0.0171025
RRP1B ribosomal RNA processing 1B -0.0170766
NALF1 NALCN channel auxiliary factor 1 -0.0170503
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 -0.0170286
DOP1B DOP1 leucine zipper like protein B -0.0170225
PRPF8 pre-mRNA processing factor 8 -0.0170025
DMWD dystrophia myotonica, WD repeat containing -0.0169987
SRSF4 serine/arginine-rich splicing factor 4 -0.0169573
IRF2BPL interferon regulatory factor 2 binding protein-like -0.0169448
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.0169097
DIAPH3 diaphanous-related formin 3 -0.0169088
KYNU kynureninase -0.016905
N4BP3 NEDD4 binding protein 3 -0.0168956
CCDC14 coiled-coil domain containing 14 -0.0168826
DTNBP1 dystrobrevin binding protein 1 -0.0168089
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B -0.0167884
ZC3H14 zinc finger CCCH-type containing 14 -0.0167742
MAML2 mastermind-like 2 (Drosophila) -0.0167639
PKP4 plakophilin 4 -0.0167275
RERG RAS-like, estrogen-regulated, growth inhibitor -0.0167131
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit -0.0167129
JPT2 Jupiter microtubule associated homolog 2 -0.0167057
OST4 oligosaccharyltransferase 4 homolog (S. cerevisiae) -0.0165326
FBXL18 F-box and leucine-rich repeat protein 18 -0.0165302
PGCKA1 PDCD10 and GCKIII kinases associated 1 -0.0165253
SRRM2 serine/arginine repetitive matrix 2 -0.0165076
BTN3A3 butyrophilin, subfamily 3, member A3 -0.0164948
APRT adenine phosphoribosyltransferase -0.0164912
TACC1 transforming, acidic coiled-coil containing protein 1 -0.0164736
SPINT1 serine peptidase inhibitor, Kunitz type 1 -0.0164708
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -0.0164571
BRCA2 breast cancer 2, early onset -0.016423
WWP2 WW domain containing E3 ubiquitin protein ligase 2 -0.0164171
ATL2 atlastin GTPase 2 -0.0164035
NF1 neurofibromin 1 -0.0163849
HNRNPK heterogeneous nuclear ribonucleoprotein K -0.0163534
UBAP2 ubiquitin associated protein 2 -0.0163529
MECP2 methyl CpG binding protein 2 -0.0163451
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like -0.0163442
SDC4 syndecan 4 -0.0163356
OSBPL10 oxysterol binding protein-like 10 -0.0162901
CC2D1A coiled-coil and C2 domain containing 1A -0.0162359
PARN poly(A)-specific ribonuclease -0.016225
OVOL2 ovo-like zinc finger 2 -0.0161718
ARTN artemin -0.0161138
CCNI cyclin I -0.0160936
ATG7 autophagy related 7 -0.0160882
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 -0.0160723
TEX2 testis expressed 2 -0.0160517
SLC38A1 solute carrier family 38, member 1 -0.0160469
UBC ubiquitin C -0.0160456
NT5C3A 5'-nucleotidase, cytosolic IIIA -0.0160442
FKBP3 FK506 binding protein 3, 25kDa -0.0160311
SH3RF1 SH3 domain containing ring finger 1 -0.0160149
RALY RALY heterogeneous nuclear ribonucleoprotein -0.0160148
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 -0.0159908
NOL11 nucleolar protein 11 -0.0159683
PHGDH phosphoglycerate dehydrogenase -0.0159682
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -0.0159526
TM9SF3 transmembrane 9 superfamily member 3 -0.0159364
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -0.0159295
DOCK6 dedicator of cytokinesis 6 -0.0159241
EPHA7 EPH receptor A7 -0.0158661
HNRNPR heterogeneous nuclear ribonucleoprotein R -0.0157902
WEE1 WEE1 G2 checkpoint kinase -0.015784
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -0.015776
G6PC3 glucose 6 phosphatase, catalytic, 3 -0.0156553
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -0.0155979
TXNIP thioredoxin interacting protein -0.0154846
RAB22A RAB22A, member RAS oncogene family -0.0153634
ADCY1 adenylate cyclase 1 (brain) -0.0153439
GLE1 GLE1 RNA export mediator -0.0153176
EML4 echinoderm microtubule associated protein like 4 -0.0152841
EDF1 endothelial differentiation-related factor 1 -0.0152435
RAD21 RAD21 homolog (S. pombe) -0.0152104
SSR1 signal sequence receptor, alpha -0.0152008
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) -0.0151997
FCHO2 FCH domain only 2 -0.0151967
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -0.0151562
EHBP1 EH domain binding protein 1 -0.015121
WHRN whirlin -0.0150562
MPG N-methylpurine-DNA glycosylase -0.0150462
TNRC6B trinucleotide repeat containing 6B -0.0150241
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -0.0150203
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.0150059
MAU2 MAU2 sister chromatid cohesion factor -0.0150031
BRD4 bromodomain containing 4 -0.0149781
COX5B cytochrome c oxidase subunit Vb -0.0149343
ARHGAP10 Rho GTPase activating protein 10 -0.0149139
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -0.0149104
TMBIM6 transmembrane BAX inhibitor motif containing 6 -0.0149024
LMX1B LIM homeobox transcription factor 1, beta -0.014899
CHD6 chromodomain helicase DNA binding protein 6 -0.0148741
INSR insulin receptor -0.0148649
PRLR prolactin receptor -0.0148527
NUP210 nucleoporin 210kDa -0.0148435
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.0148418
SRSF2 serine/arginine-rich splicing factor 2 -0.0148382
ASCC1 activating signal cointegrator 1 complex subunit 1 -0.014825
RPL18A ribosomal protein L18a -0.0148166
INTS2 integrator complex subunit 2 -0.014768
ATXN2 ataxin 2 -0.0147665
SLC38A2 solute carrier family 38, member 2 -0.0147662
METTL15 methyltransferase like 15 -0.0147534
NME1 NME/NM23 nucleoside diphosphate kinase 1 -0.0147303
RHOA ras homolog family member A -0.0147287
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0147076
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0146744
PCED1B PC-esterase domain containing 1B -0.0146688
ELF2 E74-like factor 2 (ets domain transcription factor) -0.0146669
EIF3E eukaryotic translation initiation factor 3, subunit E -0.0146648
VSIG10 V-set and immunoglobulin domain containing 10 -0.0146569
KDM2B lysine (K)-specific demethylase 2B -0.0146439
ABHD18 abhydrolase domain containing 18 -0.014614
ORC3 origin recognition complex, subunit 3 -0.0146038
SHLD2 shieldin complex subunit 2 -0.0145811
RFX7 regulatory factor X, 7 -0.0145298
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C -0.0145251
SPATA17 spermatogenesis associated 17 -0.0145119
POFUT1 protein O-fucosyltransferase 1 -0.0145093
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -0.0144948
RBM6 RNA binding motif protein 6 -0.0144762
MIPEP mitochondrial intermediate peptidase -0.0144637
EIF4B eukaryotic translation initiation factor 4B -0.0144603
BBX bobby sox homolog (Drosophila) -0.0143937
CHPF chondroitin polymerizing factor -0.0143679
RBPMS RNA binding protein with multiple splicing -0.0143596
ZNF331 zinc finger protein 331 -0.0143585
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.0143186
MAP3K14 mitogen-activated protein kinase kinase kinase 14 -0.0143128
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -0.0143076
BAZ2A bromodomain adjacent to zinc finger domain, 2A -0.0142906
EPB41L5 erythrocyte membrane protein band 4.1 like 5 -0.0142766
SIL1 SIL1 nucleotide exchange factor -0.0142517
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.0142468
UBE2B ubiquitin-conjugating enzyme E2B -0.0142382
HIP1 huntingtin interacting protein 1 -0.014191
MED12L mediator complex subunit 12-like -0.0141848
RBM10 RNA binding motif protein 10 -0.0141685
FBXO11 F-box protein 11 -0.0141565
ZC3H4 zinc finger CCCH-type containing 4 -0.014108
TASP1 taspase, threonine aspartase, 1 -0.0141002
ZNF654 zinc finger protein 654 -0.0140993
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.0140983
TM9SF4 transmembrane 9 superfamily protein member 4 -0.0140692
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -0.0140624
EEF1B2 eukaryotic translation elongation factor 1 beta 2 -0.0140615
RPS24 ribosomal protein S24 -0.0140552
CDK5RAP2 CDK5 regulatory subunit associated protein 2 -0.0140416
RPL37 ribosomal protein L37 -0.0140312
CHD4 chromodomain helicase DNA binding protein 4 -0.014021
BCAS4 breast carcinoma amplified sequence 4 -0.0140205
KIF11 kinesin family member 11 -0.0139125
HLA-E major histocompatibility complex, class I, E -0.0138828
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0138813
LATS2 large tumor suppressor kinase 2 -0.0138801
UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2 -0.0138691
MLXIP MLX interacting protein -0.0138413
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.0137717
ASB7 ankyrin repeat and SOCS box containing 7 -0.0137687
RNASE12 ribonuclease, RNase A family, 12 (non-active) -0.0137644
IFI27 interferon, alpha-inducible protein 27 -0.013753
RBL1 retinoblastoma-like 1 -0.0137515
SIK3 SIK family kinase 3 -0.0137496
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 -0.0137483
TOM1L2 target of myb1-like 2 (chicken) -0.0137416
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa -0.0137221
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 -0.0136977
HCFC1 host cell factor C1 -0.0136866
TAC4 tachykinin 4 (hemokinin) -0.0136795
SFT2D2 SFT2 domain containing 2 -0.0136737
DNAH14 dynein, axonemal, heavy chain 14 -0.0136732
COBL cordon-bleu WH2 repeat protein -0.0136571
EIPR1 EARP complex and GARP complex interacting protein 1 -0.0136056
DAD1 defender against cell death 1 -0.0136007
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) -0.0135834
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 -0.0135543
LMNA lamin A/C -0.0134958
PIGL phosphatidylinositol glycan anchor biosynthesis, class L -0.0134909
NUP205 nucleoporin 205kDa -0.0134614
NFIB nuclear factor I/B -0.0134514
CLEC16A C-type lectin domain family 16, member A -0.0133909
WSB1 WD repeat and SOCS box containing 1 -0.0133886
GEMIN5 gem (nuclear organelle) associated protein 5 -0.0133105
CHD9 chromodomain helicase DNA binding protein 9 -0.0132895
TXNL4A thioredoxin-like 4A -0.0132801
SERBP1 SERPINE1 mRNA binding protein 1 -0.0132782
RPS13 ribosomal protein S13 -0.0132682
TLK2 tousled-like kinase 2 -0.0132352
RPL14 ribosomal protein L14 -0.0131544
GINS1 GINS complex subunit 1 (Psf1 homolog) -0.0131455
SLC39A11 solute carrier family 39, member 11 -0.0131455
PPP1R3D protein phosphatase 1, regulatory subunit 3D -0.0131273
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) -0.0131272
BCR breakpoint cluster region -0.0131265
AZIN1 antizyme inhibitor 1 -0.0131255
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha -0.0131243
PLCG1 phospholipase C, gamma 1 -0.0130849
KDM4C lysine (K)-specific demethylase 4C -0.0130796
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase -0.0130749
SLC35E1 solute carrier family 35, member E1 -0.0130679
FNDC3A fibronectin type III domain containing 3A -0.013054
SETDB1 SET domain, bifurcated 1 -0.013046
UBAP1 ubiquitin associated protein 1 -0.0129918
SLF2 SMC5-SMC6 complex localization factor 2 -0.0129811
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase -0.012965
FTH1 ferritin, heavy polypeptide 1 -0.0129534
IQCK IQ motif containing K -0.0129314
MICU1 mitochondrial calcium uptake 1 -0.0129252
SMG6 SMG6 nonsense mediated mRNA decay factor -0.0129248
PDE7A phosphodiesterase 7A -0.0129126
ZNF704 zinc finger protein 704 -0.0129104