MCF7_Valproic acid sodium salt_100nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description Valproic acid sodium salt 100nM perturbation in MCF7 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the MCF7_Valproic acid sodium salt_100nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.132224
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.132204
BCAS3 breast carcinoma amplified sequence 3 0.107689
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0975026
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0846802
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.082459
SDK1 sidekick cell adhesion molecule 1 0.0719081
ESR1 estrogen receptor 1 0.0715661
GNAS GNAS complex locus 0.0650172
CTNND2 catenin (cadherin-associated protein), delta 2 0.0642491
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0627501
MKI67 marker of proliferation Ki-67 0.0617735
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0590959
PRR11 proline rich 11 0.0577581
MSI2 musashi RNA-binding protein 2 0.057006
SPTSSB serine palmitoyltransferase, small subunit B 0.055739
RPS8 ribosomal protein S8 0.0536857
CSDE1 cold shock domain containing E1, RNA-binding 0.0523027
PLXDC2 plexin domain containing 2 0.0505267
CTSD cathepsin D 0.0500387
PTPRK protein tyrosine phosphatase, receptor type, K 0.0492257
MRPL13 mitochondrial ribosomal protein L13 0.0485546
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.0472343
SCAF11 SR-related CTD-associated factor 11 0.0462991
DTNA dystrobrevin, alpha 0.0454892
ATAD2B ATPase family, AAA domain containing 2B 0.0449185
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.0445486
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 0.0443691
TBC1D5 TBC1 domain family, member 5 0.0442581
XBP1 X-box binding protein 1 0.0441502
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0439097
MAN1A2 mannosidase, alpha, class 1A, member 2 0.0432388
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.0429229
TBL1X transducin (beta)-like 1X-linked 0.0422471
SACK1B scaffolding CK1 anchoring protein B 0.0410916
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 0.040008
RAD23B RAD23 homolog B (S. cerevisiae) 0.0391335
PRLR prolactin receptor 0.0391214
PARD6B par-6 family cell polarity regulator beta 0.0389489
RPL19 ribosomal protein L19 0.0388183
ILF3 interleukin enhancer binding factor 3, 90kDa 0.038482
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.0377677
CHLSN cholesin 0.0375998
PDE8A phosphodiesterase 8A 0.0374695
HDGF hepatoma-derived growth factor 0.0372113
PXDN peroxidasin 0.0370775
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 0.0366576
CDV3 CDV3 homolog (mouse) 0.0364462
KAT6B K(lysine) acetyltransferase 6B 0.0360923
ITPRID2 ITPR interacting domain containing 2 0.0358617
SULF2 sulfatase 2 0.0358399
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.0357496
KTN1 kinectin 1 (kinesin receptor) 0.0356501
DSPP dentin sialophosphoprotein 0.0352071
PHIP pleckstrin homology domain interacting protein 0.0350531
NSD1 nuclear receptor binding SET domain protein 1 0.0348928
FNBP1 formin binding protein 1 0.0346443
RDX radixin 0.0346069
MACROD2 MACRO domain containing 2 0.0344955
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.0340622
AREG amphiregulin 0.0340431
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.033983
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 0.0339806
RAB31 RAB31, member RAS oncogene family 0.0338874
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 0.0337577
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.0336708
NHSL1 NHS-like 1 0.033447
EIF3H eukaryotic translation initiation factor 3, subunit H 0.0333714
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0332395
HIPK2 homeodomain interacting protein kinase 2 0.0330207
NRCAM neuronal cell adhesion molecule 0.0328299
DSCAM Down syndrome cell adhesion molecule 0.0328067
DNAAF9 dynein axonemal assembly factor 9 0.0324209
GREB1 growth regulation by estrogen in breast cancer 1 0.0324062
ATXN1 ataxin 1 0.0323617
KMT2C lysine (K)-specific methyltransferase 2C 0.0321039
TUBB tubulin, beta class I 0.0315809
SRPK2 SRSF protein kinase 2 0.030856
GOLGB1 golgin B1 0.0306093
SET SET nuclear proto-oncogene 0.0306056
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0304888
PHACTR4 phosphatase and actin regulator 4 0.0304871
TPR translocated promoter region, nuclear basket protein 0.030478
PCNX1 pecanex 1 0.0303954
GATAD2A GATA zinc finger domain containing 2A 0.0303543
NOL10 nucleolar protein 10 0.0302899
CENPF centromere protein F, 350/400kDa 0.0297992
OAZ1 ornithine decarboxylase antizyme 1 0.0297502
ZFHX3 zinc finger homeobox 3 0.0296958
TMSB10 thymosin beta 10 0.0296407
TLK1 tousled-like kinase 1 0.029527
RPS15 ribosomal protein S15 0.0293562
RGS6 regulator of G-protein signaling 6 0.0293431
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.0293411
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.0293181
SOS1 son of sevenless homolog 1 (Drosophila) 0.0288234
ALCAM activated leukocyte cell adhesion molecule 0.0287818
MTDH metadherin 0.0287465
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 0.0277638
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0277266
RPL7A ribosomal protein L7a 0.0277221
SHANK2 SH3 and multiple ankyrin repeat domains 2 0.0276239
CTBP2 C-terminal binding protein 2 0.0276146
TMPRSS4 transmembrane protease, serine 4 0.0276107
HSPH1 heat shock 105kDa/110kDa protein 1 0.0275201
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 0.0274405
MARK3 MAP/microtubule affinity-regulating kinase 3 0.0272698
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.027245
KIF14 kinesin family member 14 0.0272017
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.0272016
SEPTIN9 septin 9 0.0271699
ZNF280D zinc finger protein 280D 0.0271652
JMJD1C jumonji domain containing 1C 0.0268562
RPL4 ribosomal protein L4 0.0268281
TENM3 teneurin transmembrane protein 3 0.0267267
EXOC4 exocyst complex component 4 0.0266993
RPS14 ribosomal protein S14 0.0266536
RAB3D RAB3D, member RAS oncogene family 0.0263567
LARP4B La ribonucleoprotein domain family, member 4B 0.026285
RPS29 ribosomal protein S29 0.0261657
LOC112694756 uncharaterized LOC112694756 0.0260841
KANSL1 KAT8 regulatory NSL complex subunit 1 0.0259716
ARTN artemin 0.025697
DST dystonin 0.0256393
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.025509
KIF13A kinesin family member 13A 0.0251284
GPATCH2 G patch domain containing 2 0.0250324
TFF1 trefoil factor 1 0.0249923
CENPE centromere protein E, 312kDa 0.0249327
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0249244
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.024906
FRMD5 FERM domain containing 5 0.0248742
POTEF POTE ankyrin domain family, member F 0.0247989
CLOCK clock circadian regulator 0.024477
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.0244738
TRPS1 trichorhinophalangeal syndrome I 0.0244457
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.0244412
CERS6 ceramide synthase 6 0.0244104
RPS5 ribosomal protein S5 0.0243922
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.0243847
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 0.0243844
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0242739
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0242595
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0242387
TXNRD1 thioredoxin reductase 1 0.0242253
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0241884
SCAF8 SR-related CTD-associated factor 8 0.0240966
CEP350 centrosomal protein 350kDa 0.0239734
ZNF804B zinc finger protein 804B 0.0239161
SUMO2 small ubiquitin-like modifier 2 0.0239051
HSPA8 heat shock 70kDa protein 8 0.0238235
MCM9 minichromosome maintenance complex component 9 0.0237139
CCND1 cyclin D1 0.0236947
SMG6 SMG6 nonsense mediated mRNA decay factor 0.0236832
SPRED2 sprouty-related, EVH1 domain containing 2 0.0236729
USP8 ubiquitin specific peptidase 8 0.0234794
HIP1 huntingtin interacting protein 1 0.023397
EEIG2 EEIG family member 2 0.0233812
TOB1 transducer of ERBB2, 1 0.0232959
CLSTN2 calsyntenin 2 0.023285
OSGIN2 oxidative stress induced growth inhibitor family member 2 0.0232818
FGD4 FYVE, RhoGEF and PH domain containing 4 0.0232655
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.023264
PRRC2C proline-rich coiled-coil 2C 0.0232459
KIAA0586 KIAA0586 0.0232346
RHOBTB3 Rho-related BTB domain containing 3 0.0231915
MAP7 microtubule-associated protein 7 0.0231462
THOC7 THO complex 7 0.0231173
IGSF1 immunoglobulin superfamily, member 1 0.0230989
BPTF bromodomain PHD finger transcription factor 0.0230953
MED13 mediator complex subunit 13 0.023087
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 0.0228464
NF1 neurofibromin 1 0.0228419
SRPK1 SRSF protein kinase 1 0.0226433
SQLE squalene epoxidase 0.022641
EEF2 eukaryotic translation elongation factor 2 0.022521
RAD51B RAD51 paralog B 0.0224672
JAK1 Janus kinase 1 0.0224469
SLC38A1 solute carrier family 38, member 1 0.022187
CGGBP1 CGG triplet repeat binding protein 1 0.0221554
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.0221191
COL4A5 collagen, type IV, alpha 5 0.0220087
ATL3 atlastin GTPase 3 0.0219649
OSBPL1A oxysterol binding protein-like 1A 0.0219528
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 0.0219368
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.0219141
CEP290 centrosomal protein 290kDa 0.0218141
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 0.0217734
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.0216751
PRC1 protein regulator of cytokinesis 1 0.0216515
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.0215993
THOC2 THO complex 2 0.0215401
PTPRJ protein tyrosine phosphatase, receptor type, J 0.0214991
ARHGAP11B Rho GTPase activating protein 11B 0.0214708
ENO1 enolase 1, (alpha) 0.0214693
ATRN attractin 0.0214626
SEC31A SEC31 homolog A (S. cerevisiae) 0.0214118
ZMYND8 zinc finger, MYND-type containing 8 0.021388
RICTOR RPTOR independent companion of MTOR, complex 2 0.0213057
ANKRD50 ankyrin repeat domain 50 0.0212743
SRSF4 serine/arginine-rich splicing factor 4 0.0211299
HEATR5A HEAT repeat containing 5A 0.0210129
SLC30A5 solute carrier family 30 (zinc transporter), member 5 0.0209421
RPL3 ribosomal protein L3 0.0208786
THRAP3 thyroid hormone receptor associated protein 3 0.0208778
SFXN2 sideroflexin 2 0.0208007
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.0207247
GSN gelsolin 0.0206214
PALLD palladin, cytoskeletal associated protein 0.0205863
CLEC16A C-type lectin domain family 16, member A 0.0205684
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.0205278
SIPA1L3 signal-induced proliferation-associated 1 like 3 0.02049
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) 0.0204334
FBXW4 F-box and WD repeat domain containing 4 0.0204324
LCOR ligand dependent nuclear receptor corepressor 0.0203887
CFDP1 craniofacial development protein 1 0.0203831
BRD4 bromodomain containing 4 0.0203758
ARHGAP5 Rho GTPase activating protein 5 0.0203164
VEZF1 vascular endothelial zinc finger 1 0.0202877
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 0.0202733
PTMA prothymosin, alpha 0.0201978
AFG1L AFG1 like ATPase 0.0201971
ACBD6 acyl-CoA binding domain containing 6 0.0201798
CDC27 cell division cycle 27 0.0201771
NUP88 nucleoporin 88kDa 0.0201764
FAF1 Fas (TNFRSF6) associated factor 1 0.0200641
MAVS mitochondrial antiviral signaling protein 0.0200596
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.0200472
PTBP1 polypyrimidine tract binding protein 1 0.0200136
CCDC186 coiled-coil domain containing 186 0.0199947
RPS23 ribosomal protein S23 0.0198885
H4C8 H4 clustered histone 8 0.0198464
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.0198196
SASH1 SAM and SH3 domain containing 1 0.0196944
PDCD7 programmed cell death 7 0.0196703
ABHD12 abhydrolase domain containing 12 0.0196515
TNPO3 transportin 3 0.0196388
NRIP1 nuclear receptor interacting protein 1 0.0196016
TET2 tet methylcytosine dioxygenase 2 0.0195996
EXOC2 exocyst complex component 2 0.0195986
ATXN7 ataxin 7 0.0195166
RSL24D1 ribosomal L24 domain containing 1 0.0195144
NKTR natural killer cell triggering receptor 0.0194718
TUBB4B tubulin, beta 4B class IVb 0.0194653
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.0193923
RNF216 ring finger protein 216 0.0193041
NONO non-POU domain containing, octamer-binding 0.0192928
TRAPPC9 trafficking protein particle complex 9 0.0192893
IREB2 iron-responsive element binding protein 2 0.0191673
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0191119
TRAM1 translocation associated membrane protein 1 0.0190747
SCLT1 sodium channel and clathrin linker 1 0.0190304
USP34 ubiquitin specific peptidase 34 0.0190184
TBX2 T-box 2 0.019004
TSC22D2 TSC22 domain family, member 2 0.0189701
METTL2A methyltransferase like 2A 0.0189526
GPC6 glypican 6 0.0189246
ZSWIM6 zinc finger, SWIM-type containing 6 0.0189228
PLCB4 phospholipase C, beta 4 0.0187897
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.0187833
WAPL WAPL cohesin release factor 0.0187697
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 0.0187097
PKM pyruvate kinase, muscle 0.0187025
KNL1 kinetochore scaffold 1 0.0186999
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 0.0186431
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.0186126
ATXN7L1 ataxin 7-like 1 0.018545
MARVELD3 MARVEL domain containing 3 0.0184912
RNF169 ring finger protein 169 0.0184884
UBE2I ubiquitin-conjugating enzyme E2I 0.0184015
NCAPG2 non-SMC condensin II complex, subunit G2 0.0183793
POGZ pogo transposable element with ZNF domain 0.0183508
SGMS1 sphingomyelin synthase 1 0.0183457
RANBP17 RAN binding protein 17 0.0183427
RPL37A ribosomal protein L37a 0.0183299
URI1 URI1, prefoldin-like chaperone 0.0182093
IQGAP1 IQ motif containing GTPase activating protein 1 0.0180858
CCDC137 coiled-coil domain containing 137 0.0180723
CLTC clathrin, heavy chain (Hc) 0.0180215
ATG10 autophagy related 10 0.0180194
TIAM2 T-cell lymphoma invasion and metastasis 2 0.018007
PURA purine-rich element binding protein A 0.0179393
MLPH melanophilin 0.0179349
SND1 staphylococcal nuclease and tudor domain containing 1 0.0179143
CBX5 chromobox homolog 5 0.0178873
MRS2 MRS2 magnesium transporter 0.0178803
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 0.0178335
RAB22A RAB22A, member RAS oncogene family 0.0177783
SRRM2 serine/arginine repetitive matrix 2 0.0177673
PEX14 peroxisomal biogenesis factor 14 0.0177156
RNASE7 ribonuclease, RNase A family, 7 0.017663
NCAM2 neural cell adhesion molecule 2 0.017659
MRPS18B mitochondrial ribosomal protein S18B 0.0176535
SUSD6 sushi domain containing 6 0.0176383
FBXL5 F-box and leucine-rich repeat protein 5 0.0176202
KRIT1 KRIT1, ankyrin repeat containing 0.0175992
CLTB clathrin, light chain B 0.0175721
TTF1 transcription termination factor, RNA polymerase I 0.0175694
MIPOL1 mirror-image polydactyly 1 0.0174992
HP1BP3 heterochromatin protein 1, binding protein 3 0.0174392
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.0174045
SAPCD2 suppressor APC domain containing 2 0.0173978
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 0.0173629
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.0173461
ARID5B AT rich interactive domain 5B (MRF1-like) 0.0173347
PLCH1 phospholipase C, eta 1 0.0173126
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.0172669
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.0172634
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 0.0172457
RPS3A ribosomal protein S3A 0.0172295
NXNL2 nucleoredoxin-like 2 0.0171714
ENOX2 ecto-NOX disulfide-thiol exchanger 2 0.0171415
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0171299
COPG2 coatomer protein complex, subunit gamma 2 0.0171298
PCNT pericentrin 0.017121
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 0.0170848
SOX4 SRY (sex determining region Y)-box 4 0.0170665
LIMS1 LIM and senescent cell antigen-like domains 1 0.0170543
MYO5A myosin VA (heavy chain 12, myoxin) 0.0170309
DENND4C DENN/MADD domain containing 4C 0.0170079
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.0169834
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 0.0169789
AP1M2 adaptor-related protein complex 1, mu 2 subunit 0.0169701
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 0.0169274
FCHSD2 FCH and double SH3 domains 2 0.016924
TFAM transcription factor A, mitochondrial 0.0169217
TMCC1 transmembrane and coiled-coil domain family 1 0.0168864
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.0168824
R3HDM1 R3H domain containing 1 0.0168581
NUSAP1 nucleolar and spindle associated protein 1 0.0167774
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.0167625
RPL13A ribosomal protein L13a 0.0167616
NTN1 netrin 1 0.0167528
TPX2 TPX2, microtubule-associated 0.0167518
VTI1A vesicle transport through interaction with t-SNAREs 1A 0.0167123
SLC39A9 solute carrier family 39, member 9 0.0167025
TBC1D22A TBC1 domain family, member 22A 0.0166937
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 0.016667
BRD2 bromodomain containing 2 0.0166566
LYPD6B LY6/PLAUR domain containing 6B 0.0166534
SNRPA small nuclear ribonucleoprotein polypeptide A 0.0166231
MED27 mediator complex subunit 27 0.0165831
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 0.0165761
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.0165681
DSTYK dual serine/threonine and tyrosine protein kinase 0.016547
PRUNE2 prune homolog 2 (Drosophila) 0.0164805
TENT5A terminal nucleotidyltransferase 5A 0.0164583
REST RE1-silencing transcription factor 0.0163814
PHACTR2 phosphatase and actin regulator 2 0.0163798
MLEC malectin 0.0163775
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0163677
DIAPH1 diaphanous-related formin 1 0.0163225
GRK6 G protein-coupled receptor kinase 6 0.0163088
R3HDM2 R3H domain containing 2 0.0162895
SH3D19 SH3 domain containing 19 0.0162786
TMEM44 transmembrane protein 44 0.0162392
CENPB centromere protein B, 80kDa 0.0162234
RB1 retinoblastoma 1 0.0162208
SPNS1 spinster homolog 1 (Drosophila) 0.0161085
RPL21 ribosomal protein L21 0.0161055
BCLAF1 BCL2-associated transcription factor 1 0.0160844
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 0.0160467
TCERG1 transcription elongation regulator 1 0.0160188
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit 0.0159957
SETD3 SET domain containing 3 0.0159837
DCAF6 DDB1 and CUL4 associated factor 6 0.0159771
MPRIP myosin phosphatase Rho interacting protein 0.0159289
ARL15 ADP-ribosylation factor-like 15 0.0159241
PAIP2 poly(A) binding protein interacting protein 2 0.0158953
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) 0.0158782
RORA RAR-related orphan receptor A 0.0158511
BMP2K BMP2 inducible kinase 0.0158349
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.0158025
MTPN myotrophin 0.0158003
SSR1 signal sequence receptor, alpha 0.0157682
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.0157503
MRPS34 mitochondrial ribosomal protein S34 0.0157478
PIKFYVE phosphoinositide kinase, FYVE finger containing 0.0157375
UBE3A ubiquitin protein ligase E3A 0.0157331
CDK19 cyclin-dependent kinase 19 0.0157223
CDK8 cyclin-dependent kinase 8 0.0157195
MAN2A1 mannosidase, alpha, class 2A, member 1 0.0157087
FANCC Fanconi anemia, complementation group C 0.0156755
REEP5 receptor accessory protein 5 0.0156629
ZNHIT1 zinc finger, HIT-type containing 1 0.0156476
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 0.0156436
RABEP2 rabaptin, RAB GTPase binding effector protein 2 0.0156258
HRNR hornerin 0.0156003
ADARB1 adenosine deaminase, RNA-specific, B1 0.0155505
ATP11B ATPase, class VI, type 11B 0.0155426
METRN meteorin, glial cell differentiation regulator 0.0155381
SPPL2A signal peptide peptidase like 2A 0.0155105
OTUD7B OTU deubiquitinase 7B 0.0155069
GSPT1 G1 to S phase transition 1 0.0154892
RAB8A RAB8A, member RAS oncogene family 0.0154754
FRS2 fibroblast growth factor receptor substrate 2 0.0154724
MAPK3 mitogen-activated protein kinase 3 0.0154563
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0154242
MAP2K5 mitogen-activated protein kinase kinase 5 0.0154202
SLC38A2 solute carrier family 38, member 2 0.0154154
DIAPH2 diaphanous-related formin 2 0.0153979
KIF4A kinesin family member 4A 0.015397
NFE2L2 nuclear factor, erythroid 2-like 2 0.0153599
OSBPL8 oxysterol binding protein-like 8 0.0153439
BMP7 bone morphogenetic protein 7 0.0153292
CD24 CD24 molecule 0.0152896
WDR20 WD repeat domain 20 0.01528
TDG thymine-DNA glycosylase 0.0152772
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 0.015276
RERG RAS-like, estrogen-regulated, growth inhibitor 0.0152657
SMAP1 small ArfGAP 1 0.015261
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 0.0152585
ZNF704 zinc finger protein 704 0.0152337
LSR lipolysis stimulated lipoprotein receptor 0.0152255
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 0.0151955
PCNX4 pecanex 4 0.0151871
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.0151802
BCAP31 B-cell receptor-associated protein 31 0.0151741
MAP3K20 mitogen-activated protein kinase kinase kinase 20 0.0151648
IARS1 isoleucyl-tRNA synthetase 1 0.0151552
H2AZ2 H2A.Z variant histone 2 0.0151269
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0151265
ANKRD11 ankyrin repeat domain 11 0.0151051
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma 0.0150977
HSCB HscB mitochondrial iron-sulfur cluster co-chaperone 0.0150897
SIDT1 SID1 transmembrane family, member 1 0.0150716
TLK2 tousled-like kinase 2 0.0150403
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 0.0150293
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 0.0150254
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.0150142
EIF5 eukaryotic translation initiation factor 5 0.0150108
CCDC47 coiled-coil domain containing 47 0.01497
PPCDC phosphopantothenoylcysteine decarboxylase 0.0149362
C6ORF62 chromosome 6 open reading frame 62 0.0149128
FNDC3B fibronectin type III domain containing 3B 0.0148711
UBN2 ubinuclein 2 0.0148571
IDE insulin-degrading enzyme 0.0148357
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0148279
CAPNS1 calpain, small subunit 1 0.0147683
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae) 0.0147534
TUBA1B tubulin, alpha 1b 0.0147475
GSTO2 glutathione S-transferase omega 2 0.0147327
EXOSC6 exosome component 6 0.0147205
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.014681
SDCCAG8 serologically defined colon cancer antigen 8 0.0146593
FAM171B family with sequence similarity 171, member B 0.0146582
FHIP1A FHF complex subunit HOOK interacting protein 1A 0.0146325
MAX MYC associated factor X 0.0146252
SH3RF1 SH3 domain containing ring finger 1 0.0145934
SLC38A9 solute carrier family 38, member 9 0.0145504
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa 0.0145379
NBAS neuroblastoma amplified sequence 0.0145354
GOLGA8B golgin A8 family, member B 0.0145308
RPS4X ribosomal protein S4, X-linked 0.0145305
HID1 HID1 domain containing 0.0145122
GPHN gephyrin 0.0145063
SPC24 SPC24, NDC80 kinetochore complex component 0.0144603
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.0144517
BCLAF3 BCLAF1 and THRAP3 family member 3 0.0144159
TMOD3 tropomodulin 3 (ubiquitous) 0.0144075
PPIC peptidylprolyl isomerase C (cyclophilin C) 0.0143905
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.0143872
FGGY FGGY carbohydrate kinase domain containing 0.014372
TMEM168 transmembrane protein 168 0.0143666
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.0143472
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.0143343
OBSL1 obscurin-like 1 0.0143312
MEIS2 Meis homeobox 2 0.0143048
DOCK6 dedicator of cytokinesis 6 0.0142898
ROMO1 reactive oxygen species modulator 1 0.0142433
POLR1D polymerase (RNA) I polypeptide D, 16kDa 0.0142346
SSH1 slingshot protein phosphatase 1 0.0142172
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.0142172
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.0142094
RBM26 RNA binding motif protein 26 0.0141723
MT2A metallothionein 2A 0.0141558
PIAS1 protein inhibitor of activated STAT, 1 0.0141424
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.0141316
FBXL17 F-box and leucine-rich repeat protein 17 0.0141307
EFCAB14 EF-hand calcium binding domain 14 0.0141209
RNFT2 ring finger protein, transmembrane 2 0.0141093
CSNK1G3 casein kinase 1, gamma 3 0.0141086
POLR3B polymerase (RNA) III (DNA directed) polypeptide B 0.0140629
ZNF451 zinc finger protein 451 0.0140426
COPA coatomer protein complex, subunit alpha 0.014039
C9ORF85 chromosome 9 open reading frame 85 0.0140181
AGR3 anterior gradient 3 0.0139876
MCF2L MCF.2 cell line derived transforming sequence-like 0.0139764
PNN pinin, desmosome associated protein 0.013932
RPL6 ribosomal protein L6 0.0139002
TERF2IP telomeric repeat binding factor 2, interacting protein 0.0138811
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.0138691
EP300 E1A binding protein p300 0.0138656
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.0138562
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.0138412
SPC25 SPC25, NDC80 kinetochore complex component 0.0137989
NOL8 nucleolar protein 8 0.0137957
RBM14-RBM4 RBM14-RBM4 readthrough 0.0137818
FAXDC2 fatty acid hydroxylase domain containing 2 0.013777
SYT12 synaptotagmin XII 0.0137666

decreased expression

Symbol Name Standardized Value
IFI6 interferon, alpha-inducible protein 6 -0.157297
WWOX WW domain containing oxidoreductase -0.131442
NCOA3 nuclear receptor coactivator 3 -0.121124
IGF1R insulin-like growth factor 1 receptor -0.109522
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.0941235
TPM4 tropomyosin 4 -0.0925481
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0831669
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -0.0752836
PACS1 phosphofurin acidic cluster sorting protein 1 -0.0729713
GFRA1 GDNF family receptor alpha 1 -0.0721759
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0617436
KRT8 keratin 8, type II -0.0603933
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) -0.0591876
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0591396
THSD4 thrombospondin, type I, domain containing 4 -0.0579109
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 -0.0578762
AGR2 anterior gradient 2 -0.0568172
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.050535
FANCA Fanconi anemia, complementation group A -0.0491291
VMP1 vacuole membrane protein 1 -0.0459758
EVL Enah/Vasp-like -0.0458192
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -0.0457383
USP32 ubiquitin specific peptidase 32 -0.0451886
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -0.0439641
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -0.0432025
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.0430249
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.0426179
KYNU kynureninase -0.0424582
SYTL2 synaptotagmin-like 2 -0.0424018
NPAS3 neuronal PAS domain protein 3 -0.0423409
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0419782
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.0405196
MRTFA myocardin related transcription factor A -0.0401521
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.0399076
MYH9 myosin, heavy chain 9, non-muscle -0.0397302
RBM39 RNA binding motif protein 39 -0.0395457
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.039315
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -0.0391982
PUM1 pumilio RNA-binding family member 1 -0.0389613
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.0387148
JUP junction plakoglobin -0.038476
RPL37 ribosomal protein L37 -0.0376777
RACK1 receptor for activated C kinase 1 -0.0376198
VCL vinculin -0.0366634
CCSER1 coiled-coil serine-rich protein 1 -0.0366514
ZNF217 zinc finger protein 217 -0.0363717
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.0361175
ZNF638 zinc finger protein 638 -0.036097
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 -0.0356013
SVIL supervillin -0.0355504
FXYD3 FXYD domain containing ion transport regulator 3 -0.0352155
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 -0.0349314
FLNA filamin A, alpha -0.034719
RPL18 ribosomal protein L18 -0.0345781
GLG1 golgi glycoprotein 1 -0.0344773
SKA2 spindle and kinetochore associated complex subunit 2 -0.0340509
ATAD2 ATPase family, AAA domain containing 2 -0.0339501
MECP2 methyl CpG binding protein 2 -0.0338445
RAB10 RAB10, member RAS oncogene family -0.0336415
MALRD1 MAM and LDL receptor class A domain containing 1 -0.0335742
SPIDR scaffolding protein involved in DNA repair -0.0334188
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0333917
OSBPL10 oxysterol binding protein-like 10 -0.0327245
GRHL2 grainyhead-like 2 (Drosophila) -0.0323827
PDXK pyridoxal (pyridoxine, vitamin B6) kinase -0.0323433
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0321519
NEMF nuclear export mediator factor -0.0319808
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -0.0316626
ADNP activity-dependent neuroprotector homeobox -0.0315895
CENPP centromere protein P -0.0310643
FAM168B family with sequence similarity 168, member B -0.0308707
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 -0.0308373
PBX1 pre-B-cell leukemia homeobox 1 -0.0303892
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -0.0301481
NPNT nephronectin -0.0301083
CLIC4 chloride intracellular channel 4 -0.0299383
VAV3 vav 3 guanine nucleotide exchange factor -0.0297825
ERBB3 erb-b2 receptor tyrosine kinase 3 -0.029419
AVL9 AVL9 homolog (S. cerevisiase) -0.0293948
NCOA2 nuclear receptor coactivator 2 -0.029326
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.0292371
RPLP1 ribosomal protein, large, P1 -0.0290965
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 -0.029012
PBX3 pre-B-cell leukemia homeobox 3 -0.0288636
CD81 CD81 molecule -0.0287603
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -0.0287214
TAPBP TAP binding protein (tapasin) -0.0286946
RALY RALY heterogeneous nuclear ribonucleoprotein -0.0284455
RBM15 RNA binding motif protein 15 -0.028392
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0282955
MBTD1 mbt domain containing 1 -0.028085
RPS3 ribosomal protein S3 -0.0279961
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -0.0278108
UGDH UDP-glucose 6-dehydrogenase -0.0277943
LPP LIM domain containing preferred translocation partner in lipoma -0.0277799
FBXO42 F-box protein 42 -0.0277749
BCL2 B-cell CLL/lymphoma 2 -0.0276172
IRS1 insulin receptor substrate 1 -0.027353
CTSB cathepsin B -0.0273467
RAB21 RAB21, member RAS oncogene family -0.027004
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0268553
GATAD2B GATA zinc finger domain containing 2B -0.0267014
NUP160 nucleoporin 160kDa -0.0265808
RPN1 ribophorin I -0.0265432
PPP6R3 protein phosphatase 6, regulatory subunit 3 -0.0265139
CLSTN1 calsyntenin 1 -0.0262974
ATP9A ATPase, class II, type 9A -0.0262893
PCED1B PC-esterase domain containing 1B -0.0261949
TUBD1 tubulin, delta 1 -0.0261036
RABL6 RAB, member RAS oncogene family-like 6 -0.0260997
MBD5 methyl-CpG binding domain protein 5 -0.0260026
GPATCH8 G patch domain containing 8 -0.0258647
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.0258042
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 -0.0254429
LARP1 La ribonucleoprotein domain family, member 1 -0.0254236
PA2G4 proliferation-associated 2G4, 38kDa -0.0254229
SEC16A SEC16 homolog A (S. cerevisiae) -0.0251993
ARHGAP12 Rho GTPase activating protein 12 -0.0251676
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 -0.0251564
DIDO1 death inducer-obliterator 1 -0.0251561
AKAP13 A kinase (PRKA) anchor protein 13 -0.0250905
RABGAP1 RAB GTPase activating protein 1 -0.0249971
TMEM65 transmembrane protein 65 -0.0248828
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) -0.0248585
CDK13 cyclin-dependent kinase 13 -0.0248474
MECOM MDS1 and EVI1 complex locus -0.0247748
PLXNA4 plexin A4 -0.024758
BLTP2 bridge-like lipid transfer protein family member 2 -0.0247496
DLG1 discs, large homolog 1 (Drosophila) -0.0244598
MREG melanoregulin -0.0242562
DOP1B DOP1 leucine zipper like protein B -0.0242028
PTPRG protein tyrosine phosphatase, receptor type, G -0.0241104
ABHD2 abhydrolase domain containing 2 -0.0241046
PDE7A phosphodiesterase 7A -0.0240806
EPN2 epsin 2 -0.0240084
TM9SF3 transmembrane 9 superfamily member 3 -0.0238714
ANO10 anoctamin 10 -0.0238538
PUM2 pumilio RNA-binding family member 2 -0.0237857
SPPL3 signal peptide peptidase like 3 -0.0236513
SNX8 sorting nexin 8 -0.0235975
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -0.0234841
LITAF lipopolysaccharide-induced TNF factor -0.0234527
FMN1 formin 1 -0.0234102
CD9 CD9 molecule -0.0233512
CUX1 cut-like homeobox 1 -0.0233481
EPHA4 EPH receptor A4 -0.023278
PAWR PRKC, apoptosis, WT1, regulator -0.0232396
CHD6 chromodomain helicase DNA binding protein 6 -0.0230442
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.0229817
RPL31 ribosomal protein L31 -0.0229513
SLC35E1 solute carrier family 35, member E1 -0.0229248
MIDEAS mitotic deacetylase associated SANT domain protein -0.0228709
DNASE1L1 deoxyribonuclease I-like 1 -0.0228211
MZT2A mitotic spindle organizing protein 2A -0.0226089
AGO3 argonaute RISC catalytic component 3 -0.0225474
FBXO33 F-box protein 33 -0.0225066
TPD52 tumor protein D52 -0.0224627
CYBA cytochrome b-245, alpha polypeptide -0.0223689
U2SURP U2 snRNP-associated SURP domain containing -0.022335
FOXO1 forkhead box O1 -0.0222991
KDM2B lysine (K)-specific demethylase 2B -0.022264
CAMK1D calcium/calmodulin-dependent protein kinase ID -0.0222473
ANXA2 annexin A2 -0.0222464
UBR2 ubiquitin protein ligase E3 component n-recognin 2 -0.0221003
GEMIN5 gem (nuclear organelle) associated protein 5 -0.022099
ESRP1 epithelial splicing regulatory protein 1 -0.0219932
FLNB filamin B, beta -0.0219856
PRKD2 protein kinase D2 -0.0218071
NVL nuclear VCP-like -0.0217848
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -0.0217591
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) -0.0217094
MACC1 metastasis associated in colon cancer 1 -0.0217069
SPATS2 spermatogenesis associated, serine-rich 2 -0.0217006
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.0216099
TRIM56 tripartite motif containing 56 -0.021512
TMEM150C transmembrane protein 150C -0.0214781
TOGARAM1 TOG array regulator of axonemal microtubules 1 -0.0213505
PDCD6IP programmed cell death 6 interacting protein -0.0212882
MCM3AP minichromosome maintenance complex component 3 associated protein -0.0212847
VWA8 von Willebrand factor A domain containing 8 -0.0212509
RAP1B RAP1B, member of RAS oncogene family -0.0211983
IRF2BPL interferon regulatory factor 2 binding protein-like -0.021089
ZMYM4 zinc finger, MYM-type 4 -0.0210847
BTBD9 BTB (POZ) domain containing 9 -0.0209963
INSR insulin receptor -0.0209837
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit -0.0209707
ALKBH5 AlkB family member 5, RNA demethylase -0.0209643
RNASE3 ribonuclease, RNase A family, 3 -0.0209082
SETD5 SET domain containing 5 -0.0208872
HLA-A major histocompatibility complex, class I, A -0.0208847
PAPOLA poly(A) polymerase alpha -0.020862
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa -0.0208498
HACD2 3-hydroxyacyl-CoA dehydratase 2 -0.0208496
GRID1 glutamate receptor, ionotropic, delta 1 -0.020848
DCAF10 DDB1 and CUL4 associated factor 10 -0.0208199
CHD4 chromodomain helicase DNA binding protein 4 -0.0207537
NUDC nudC nuclear distribution protein -0.0207317
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 -0.0207274
TUFM Tu translation elongation factor, mitochondrial -0.020707
IFI27 interferon, alpha-inducible protein 27 -0.0206713
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -0.0206293
EPC1 enhancer of polycomb homolog 1 (Drosophila) -0.0205335
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -0.0205179
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0204985
EP400 E1A binding protein p400 -0.020497
MYO1E myosin IE -0.0203676
RABGAP1L RAB GTPase activating protein 1-like -0.0203432
VASP vasodilator-stimulated phosphoprotein -0.0203371
PPP6R2 protein phosphatase 6, regulatory subunit 2 -0.0202994
PTGES2 prostaglandin E synthase 2 -0.0202401
UEVLD UEV and lactate/malate dehyrogenase domains -0.0202353
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -0.0202265
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.0202186
CBX1 chromobox homolog 1 -0.020218
GTF2I general transcription factor IIi -0.0202071
STOX2 storkhead box 2 -0.0201757
POU2F1 POU class 2 homeobox 1 -0.0201725
MAPK10 mitogen-activated protein kinase 10 -0.0201614
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) -0.0201582
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0201331
TJP1 tight junction protein 1 -0.0200925
COG8 component of oligomeric golgi complex 8 -0.0200666
UBE2B ubiquitin-conjugating enzyme E2B -0.0200555
ATG7 autophagy related 7 -0.0200387
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -0.0200196
RAD9A RAD9 homolog A (S. pombe) -0.0199391
NCKAP5 NCK-associated protein 5 -0.019937
RNPS1 RNA binding protein S1, serine-rich domain -0.0198716
BAZ1A bromodomain adjacent to zinc finger domain, 1A -0.0198685
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 -0.0197228
RPS18 ribosomal protein S18 -0.0196947
UBC ubiquitin C -0.0196892
PARP6 poly (ADP-ribose) polymerase family, member 6 -0.0195321
SIK3 SIK family kinase 3 -0.0194791
FAM222B family with sequence similarity 222, member B -0.0194777
MICU1 mitochondrial calcium uptake 1 -0.0194396
DCDC2 doublecortin domain containing 2 -0.0194218
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit -0.0193669
AKAP10 A kinase (PRKA) anchor protein 10 -0.0193016
WASHC5 WASH complex subunit 5 -0.0192597
GAPVD1 GTPase activating protein and VPS9 domains 1 -0.0192082
ARHGAP24 Rho GTPase activating protein 24 -0.019193
CPA6 carboxypeptidase A6 -0.0191429
TBRG4 transforming growth factor beta regulator 4 -0.0191341
ATXN2 ataxin 2 -0.0190844
APOD apolipoprotein D -0.0190798
IRF3 interferon regulatory factor 3 -0.0190165
AK1 adenylate kinase 1 -0.0189609
CUL3 cullin 3 -0.0188136
COX4I1 cytochrome c oxidase subunit IV isoform 1 -0.0187957
ZMYM5 zinc finger, MYM-type 5 -0.0187189
PCNX2 pecanex 2 -0.018718
HSPB1 heat shock 27kDa protein 1 -0.0186993
EMCN endomucin -0.0186628
RHEB Ras homolog enriched in brain -0.0185835
DEPDC5 DEP domain containing 5 -0.0185522
FANCM Fanconi anemia, complementation group M -0.0185171
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -0.0184174
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 -0.0184113
SECISBP2 SECIS binding protein 2 -0.0183976
MAP2K1 mitogen-activated protein kinase kinase 1 -0.018309
SOD2 superoxide dismutase 2, mitochondrial -0.0182974
CANT1 calcium activated nucleotidase 1 -0.0182893
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.0182665
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -0.0182628
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 -0.0182187
TRIM25 tripartite motif containing 25 -0.018148
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -0.0181315
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.018116
ITGB5 integrin, beta 5 -0.0180945
TMEM178B transmembrane protein 178B -0.0180306
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 -0.0179375
BBLN bublin coiled coil protein -0.017904
TUBA1C tubulin, alpha 1c -0.0178602
ITM2B integral membrane protein 2B -0.0178434
TRIM44 tripartite motif containing 44 -0.0178271
MON2 MON2 homolog (S. cerevisiae) -0.0178233
CHPT1 choline phosphotransferase 1 -0.0178215
CREBBP CREB binding protein -0.0178072
MTOR mechanistic target of rapamycin (serine/threonine kinase) -0.0176843
HELZ2 helicase with zinc finger 2, transcriptional coactivator -0.017666
CNKSR3 CNKSR family member 3 -0.0176308
PRMT2 protein arginine methyltransferase 2 -0.0176292
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -0.0175851
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 -0.0175534
GCC2 GRIP and coiled-coil domain containing 2 -0.0175337
CCNY cyclin Y -0.0175166
LYPD3 LY6/PLAUR domain containing 3 -0.0174874
RPL32 ribosomal protein L32 -0.0174551
ARF4 ADP-ribosylation factor 4 -0.0173143
VGLL4 vestigial-like family member 4 -0.0172791
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.0172506
IPO7 importin 7 -0.0171611
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 -0.0171237
SLC16A6 solute carrier family 16, member 6 -0.0170726
EIF3D eukaryotic translation initiation factor 3, subunit D -0.0170651
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 -0.0170641
LNPEP leucyl/cystinyl aminopeptidase -0.0169814
MTMR4 myotubularin related protein 4 -0.0169416
ACOT7 acyl-CoA thioesterase 7 -0.0169172
SNX9 sorting nexin 9 -0.0168232
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -0.0167984
VAV2 vav 2 guanine nucleotide exchange factor -0.0167189
WSB1 WD repeat and SOCS box containing 1 -0.0167099
DSTN destrin (actin depolymerizing factor) -0.0167083
USP37 ubiquitin specific peptidase 37 -0.0167041
MAML3 mastermind-like 3 (Drosophila) -0.0166928
IFITM3 interferon induced transmembrane protein 3 -0.0166881
NELFA negative elongation factor complex member A -0.0166573
IDI1 isopentenyl-diphosphate delta isomerase 1 -0.0165396
RANBP9 RAN binding protein 9 -0.0165347
ICMT isoprenylcysteine carboxyl methyltransferase -0.0165321
FKBP15 FK506 binding protein 15, 133kDa -0.0165082
UBXN2A UBX domain protein 2A -0.0165004
RNF149 ring finger protein 149 -0.0164968
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -0.0164732
TPT1 tumor protein, translationally-controlled 1 -0.0164725
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 -0.0163413
RREB1 ras responsive element binding protein 1 -0.0163242
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) -0.0163182
DLG5 discs, large homolog 5 (Drosophila) -0.0162796
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -0.0162698
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.0161662
COMMD10 COMM domain containing 10 -0.0161499
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -0.0161115
NCOA6 nuclear receptor coactivator 6 -0.0161008
VTA1 vesicle (multivesicular body) trafficking 1 -0.0160619
DOCK1 dedicator of cytokinesis 1 -0.01604
PCDH7 protocadherin 7 -0.0160028
RCOR1 REST corepressor 1 -0.0159588
AKIRIN1 akirin 1 -0.0159339
PDZRN3 PDZ domain containing ring finger 3 -0.0159183
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 -0.0158895
ZNF146 zinc finger protein 146 -0.015854
VSIG10 V-set and immunoglobulin domain containing 10 -0.0158537
H1-10 H1.10 linker histone -0.0158357
TERF2 telomeric repeat binding factor 2 -0.0158122
KIAA1671 KIAA1671 -0.0157973
HAT1 histone acetyltransferase 1 -0.0157905
TCAIM T cell activation inhibitor, mitochondrial -0.0157753
ZZZ3 zinc finger, ZZ-type containing 3 -0.0157618
USP3 ubiquitin specific peptidase 3 -0.0157461
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0157421
DRC8 dynein regulatory complex subunit 8 -0.0157271
ATOSA atos homolog A -0.0157142
PRUNE1 prune exopolyphosphatase 1 -0.0157065
SERINC3 serine incorporator 3 -0.0156996
SEPTIN6 septin 6 -0.01568
AFTPH aftiphilin -0.0156697
TNPO1 transportin 1 -0.015619
MTSS1 metastasis suppressor 1 -0.0156161
SLC30A7 solute carrier family 30 (zinc transporter), member 7 -0.0155844
XYLB xylulokinase homolog (H. influenzae) -0.0155684
ERMP1 endoplasmic reticulum metallopeptidase 1 -0.0155568
KLHL28 kelch-like family member 28 -0.0155503
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 -0.0155033
IL10RB interleukin 10 receptor, beta -0.0154597
RPL36 ribosomal protein L36 -0.0154556
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0154276
SHROOM2 shroom family member 2 -0.015398
LUC7L LUC7-like (S. cerevisiae) -0.0153599
UVRAG UV radiation resistance associated -0.0153359
PRRC2B proline-rich coiled-coil 2B -0.015331
PIEZO1 piezo-type mechanosensitive ion channel component 1 -0.0153303
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 -0.0152608
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -0.0152461
MED14 mediator complex subunit 14 -0.015234
SKIL SKI-like proto-oncogene -0.0151784
TMEM181 transmembrane protein 181 -0.0151749
SINHCAF SIN3-HDAC complex associated factor -0.0150705
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -0.0150119
ANKRD23 ankyrin repeat domain 23 -0.0150074
S100A10 S100 calcium binding protein A10 -0.0149962
EPCAM epithelial cell adhesion molecule -0.0149952
ORC5 origin recognition complex, subunit 5 -0.0149474
ORC3 origin recognition complex, subunit 3 -0.0149329
EFR3A EFR3 homolog A (S. cerevisiae) -0.0149014
B2M beta-2-microglobulin -0.0148951
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.0148639
ZNF519 zinc finger protein 519 -0.0148405
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0148321
L2HGDH L-2-hydroxyglutarate dehydrogenase -0.0148264
CIAO1 cytosolic iron-sulfur assembly component 1 -0.0148096
GUK1 guanylate kinase 1 -0.014806
ZFAND6 zinc finger, AN1-type domain 6 -0.0147902
ECD ecdysoneless homolog (Drosophila) -0.0147891
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) -0.0147808
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type -0.0147671
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.0147648
SMIM14 small integral membrane protein 14 -0.0147517
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2 -0.0147383
RPS17 ribosomal protein S17 -0.0147235
TYSND1 trypsin domain containing 1 -0.0147174
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -0.0146729
BIRC6 baculoviral IAP repeat containing 6 -0.014664
FGF13 fibroblast growth factor 13 -0.0146499
WWC2 WW and C2 domain containing 2 -0.0146373
MAP4 microtubule-associated protein 4 -0.0146292
MLH3 mutL homolog 3 -0.0146127
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.014606
SMC4 structural maintenance of chromosomes 4 -0.0146057
LMAN2 lectin, mannose-binding 2 -0.0145982
PPA2 pyrophosphatase (inorganic) 2 -0.0145579
MYO9B myosin IXB -0.0145567
UBA1 ubiquitin-like modifier activating enzyme 1 -0.014521
SPTAN1 spectrin, alpha, non-erythrocytic 1 -0.0145186
WEE1 WEE1 G2 checkpoint kinase -0.0145087
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit -0.0144981
MACO1 macoilin 1 -0.0144965
HNRNPLL heterogeneous nuclear ribonucleoprotein L-like -0.0144801
HMBOX1 homeobox containing 1 -0.0144739
NDFIP1 Nedd4 family interacting protein 1 -0.014451
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 -0.0144317
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) -0.0144279
GMCL1 germ cell-less, spermatogenesis associated 1 -0.0144165
ASXL1 additional sex combs like transcriptional regulator 1 -0.0143912
ANO6 anoctamin 6 -0.0142981
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 -0.0142768
ZBTB43 zinc finger and BTB domain containing 43 -0.0142735
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -0.0142585
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 -0.0142583
TRRAP transformation/transcription domain-associated protein -0.0142219
RFX7 regulatory factor X, 7 -0.014212
MFSD12 major facilitator superfamily domain containing 12 -0.0141863
SKAP2 src kinase associated phosphoprotein 2 -0.0141796
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 -0.0141698
HDLBP high density lipoprotein binding protein -0.0141697
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0141669
MAP3K2 mitogen-activated protein kinase kinase kinase 2 -0.0141232
TMEM267 transmembrane protein 267 -0.0140909
SMYD2 SET and MYND domain containing 2 -0.0140811
BFAR bifunctional apoptosis regulator -0.0140763
TMEM245 transmembrane protein 245 -0.0140666
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) -0.0140569
BAG3 BCL2-associated athanogene 3 -0.0140512
LIN52 lin-52 DREAM MuvB core complex component -0.0140411
UBAP2 ubiquitin associated protein 2 -0.0140389
ARHGAP35 Rho GTPase activating protein 35 -0.0140325
CD164 CD164 molecule, sialomucin -0.0140301
ITPKC inositol-trisphosphate 3-kinase C -0.014012
CELF1 CUGBP, Elav-like family member 1 -0.0139923
SYT10 synaptotagmin X -0.0139893
RNF121 ring finger protein 121 -0.0139856
MKRN1 makorin ring finger protein 1 -0.0139727
GAK cyclin G associated kinase -0.0139641
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.0139627
ZNF710 zinc finger protein 710 -0.0139604
ARSG arylsulfatase G -0.0139537
PHF14 PHD finger protein 14 -0.0139353
MGP matrix Gla protein -0.0139306
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 -0.013928
UBQLN1 ubiquilin 1 -0.0139102
EHD4 EH-domain containing 4 -0.0138272
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) -0.0138211
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -0.0138164
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) -0.0137989
APP amyloid beta (A4) precursor protein -0.0137888
RIGI RNA sensor RIG-I -0.0137854
RAB5A RAB5A, member RAS oncogene family -0.0137582
SYNPO2 synaptopodin 2 -0.0137572
IGF2R insulin-like growth factor 2 receptor -0.013752
ZNFX1 zinc finger, NFX1-type containing 1 -0.0137453
PACS2 phosphofurin acidic cluster sorting protein 2 -0.0137384
RBM23 RNA binding motif protein 23 -0.0137281
ARFIP1 ADP-ribosylation factor interacting protein 1 -0.0136943
ERBIN erbb2 interacting protein -0.01368
NUP107 nucleoporin 107kDa -0.013652
CAMKMT calmodulin-lysine N-methyltransferase -0.0136488
RPS24 ribosomal protein S24 -0.0136473
NUMB numb homolog (Drosophila) -0.0136021
TTC39B tetratricopeptide repeat domain 39B -0.0135741
ZNF318 zinc finger protein 318 -0.0135322
FUS FUS RNA binding protein -0.013529
CD44 CD44 molecule (Indian blood group) -0.0135121
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.0135036
KHDC4 KH domain containing 4, pre-mRNA splicing factor -0.0135013
PLXND1 plexin D1 -0.0134817
ITCH itchy E3 ubiquitin protein ligase -0.0134485
RBM10 RNA binding motif protein 10 -0.0134429
APLP2 amyloid beta (A4) precursor-like protein 2 -0.0134401
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -0.0134032
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 -0.0133722
ZMPSTE24 zinc metallopeptidase STE24 -0.0133618
ACLY ATP citrate lyase -0.0133553
C19ORF53 chromosome 19 open reading frame 53 -0.0133384
KANSL3 KAT8 regulatory NSL complex subunit 3 -0.013324
CENPN centromere protein N -0.0133112
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 -0.013288
PER2 period circadian clock 2 -0.0132727
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -0.0132398
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) -0.0132299
PFKP phosphofructokinase, platelet -0.0132123
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.013197
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -0.0131961
PLXNA3 plexin A3 -0.0131664
SRP54 signal recognition particle 54kDa -0.0131524
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -0.0131373
PKN1 protein kinase N1 -0.0131249
TSEN2 TSEN2 tRNA splicing endonuclease subunit -0.01308
UBN1 ubinuclein 1 -0.0130146