MCF7_Valproic acid sodium salt_10nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description Valproic acid sodium salt 10nM perturbation in MCF7 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the MCF7_Valproic acid sodium salt_10nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
BCAS3 breast carcinoma amplified sequence 3 0.134688
KRT18 keratin 18, type I 0.130794
THSD4 thrombospondin, type I, domain containing 4 0.107731
ESR1 estrogen receptor 1 0.0987177
EMP2 epithelial membrane protein 2 0.0886345
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 0.087067
NRCAM neuronal cell adhesion molecule 0.0835892
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.0810652
MALRD1 MAM and LDL receptor class A domain containing 1 0.0749652
GREB1 growth regulation by estrogen in breast cancer 1 0.073661
LMBR1 limb development membrane protein 1 0.0721664
TMEM64 transmembrane protein 64 0.0650367
IGFBP5 insulin-like growth factor binding protein 5 0.0584757
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.0579709
RHOBTB3 Rho-related BTB domain containing 3 0.0579616
NRG3 neuregulin 3 0.0564275
SPTSSB serine palmitoyltransferase, small subunit B 0.0555236
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.055035
LRP1B low density lipoprotein receptor-related protein 1B 0.0541788
GRHL2 grainyhead-like 2 (Drosophila) 0.0539055
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.0526047
CNKSR3 CNKSR family member 3 0.0519214
EVL Enah/Vasp-like 0.0512787
DCDC2 doublecortin domain containing 2 0.0506039
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.0485811
GOLGB1 golgin B1 0.0471645
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) 0.0455167
MSI2 musashi RNA-binding protein 2 0.0451773
TBC1D5 TBC1 domain family, member 5 0.0445366
SYTL2 synaptotagmin-like 2 0.0441292
ELOF1 elongation factor 1 homolog (S. cerevisiae) 0.0429507
PARD6B par-6 family cell polarity regulator beta 0.0426032
ERBB4 erb-b2 receptor tyrosine kinase 4 0.0423713
MACROD2 MACRO domain containing 2 0.0417291
IGFBP4 insulin-like growth factor binding protein 4 0.041352
MYO9A myosin IXA 0.0408164
CYB561 cytochrome b561 0.0401829
CDK19 cyclin-dependent kinase 19 0.0393622
BCL2L1 BCL2-like 1 0.0384877
CPA6 carboxypeptidase A6 0.0382768
INVS inversin 0.0380818
TPD52L1 tumor protein D52-like 1 0.0380452
RBM47 RNA binding motif protein 47 0.0378594
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0371654
PARD3 par-3 family cell polarity regulator 0.0370488
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.0370111
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.0367405
KTN1 kinectin 1 (kinesin receptor) 0.0365788
STARD13 StAR-related lipid transfer (START) domain containing 13 0.0357914
FRYL FRY-like 0.0357716
PTPRG protein tyrosine phosphatase, receptor type, G 0.0348056
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 0.0346066
DNMBP dynamin binding protein 0.0342601
SFXN2 sideroflexin 2 0.0341671
ALCAM activated leukocyte cell adhesion molecule 0.032922
PBX1 pre-B-cell leukemia homeobox 1 0.0325045
NT5C2 5'-nucleotidase, cytosolic II 0.0324142
GAN gigaxonin 0.032369
MLPH melanophilin 0.032055
TUBD1 tubulin, delta 1 0.0320126
SPIDR scaffolding protein involved in DNA repair 0.0319678
TMEM164 transmembrane protein 164 0.0319215
DCPH1 damage control phosphatase 1 0.0318951
SEZ6L2 seizure related 6 homolog (mouse)-like 2 0.0317786
CLASP2 cytoplasmic linker associated protein 2 0.0314913
MED13 mediator complex subunit 13 0.0311253
CTSD cathepsin D 0.0310451
FDPS farnesyl diphosphate synthase 0.0310208
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0308519
AMZ1 archaelysin family metallopeptidase 1 0.0308477
GREB1L growth regulation by estrogen in breast cancer-like 0.0306587
SLC38A1 solute carrier family 38, member 1 0.0306349
NECAB1 N-terminal EF-hand calcium binding protein 1 0.0303657
IGF1R insulin-like growth factor 1 receptor 0.0300135
KANSL1 KAT8 regulatory NSL complex subunit 1 0.0298024
DST dystonin 0.0297929
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.029604
C14ORF132 chromosome 14 open reading frame 132 0.0291751
PSEN1 presenilin 1 0.0289961
ZNF804B zinc finger protein 804B 0.0289054
GATAD2B GATA zinc finger domain containing 2B 0.0285483
CLDN3 claudin 3 0.0283225
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.0282726
TMCC1 transmembrane and coiled-coil domain family 1 0.0279882
NTN1 netrin 1 0.0277592
HIP1 huntingtin interacting protein 1 0.0274262
PLXDC2 plexin domain containing 2 0.0273892
ITSN2 intersectin 2 0.0273122
ZNF609 zinc finger protein 609 0.0272954
CCDC170 coiled-coil domain containing 170 0.0272262
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.0271223
VIRMA vir like m6A methyltransferase associated 0.0264219
TEX14 testis expressed 14 0.0259169
SOS2 son of sevenless homolog 2 (Drosophila) 0.025891
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.025499
GNAS GNAS complex locus 0.0254581
GLCCI1 glucocorticoid induced 1 0.0250912
STK24 serine/threonine kinase 24 0.0247591
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.0245088
SLC39A11 solute carrier family 39, member 11 0.0244595
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.0243805
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.0243497
RNF169 ring finger protein 169 0.0241331
LAMP2 lysosomal-associated membrane protein 2 0.0239726
DENND4A DENN/MADD domain containing 4A 0.0238473
ABHD2 abhydrolase domain containing 2 0.0238137
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 0.0238095
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 0.0237847
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0235797
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.0235537
CST3 cystatin C 0.0235105
C6ORF141 chromosome 6 open reading frame 141 0.0233609
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.0233058
KIAA0319L KIAA0319-like 0.0232625
CHD4 chromodomain helicase DNA binding protein 4 0.0232482
ZHX3 zinc fingers and homeoboxes 3 0.023113
FAM193A family with sequence similarity 193, member A 0.0230728
TM9SF3 transmembrane 9 superfamily member 3 0.0230529
MRTFB myocardin related transcription factor B 0.0230279
MECOM MDS1 and EVI1 complex locus 0.0228626
CUEDC1 CUE domain containing 1 0.0227368
MAP2K5 mitogen-activated protein kinase kinase 5 0.022653
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.0226171
LLGL2 lethal giant larvae homolog 2 (Drosophila) 0.0225625
KDM5B lysine (K)-specific demethylase 5B 0.0224099
C21ORF58 chromosome 21 open reading frame 58 0.0223405
PHACTR2 phosphatase and actin regulator 2 0.022329
UBE2R2 ubiquitin-conjugating enzyme E2R 2 0.0221695
PDE8A phosphodiesterase 8A 0.0221641
MTREX Mtr4 exosome RNA helicase 0.0221607
PRKCA protein kinase C, alpha 0.0221373
SHISA9 shisa family member 9 0.022012
RPL3 ribosomal protein L3 0.0219592
OXR1 oxidation resistance 1 0.021863
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.0218489
NBEAL1 neurobeachin-like 1 0.0217943
RET ret proto-oncogene 0.0217404
PTGES2 prostaglandin E synthase 2 0.0216146
TMEM178B transmembrane protein 178B 0.0215737
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 0.0215713
TMEM131 transmembrane protein 131 0.0214319
LARP1 La ribonucleoprotein domain family, member 1 0.0214069
APOD apolipoprotein D 0.0213383
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.021299
SLC38A2 solute carrier family 38, member 2 0.0210763
PAPOLA poly(A) polymerase alpha 0.0210577
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.0210572
NCOR1 nuclear receptor corepressor 1 0.0209953
HSCB HscB mitochondrial iron-sulfur cluster co-chaperone 0.0209403
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.020934
TCF25 transcription factor 25 (basic helix-loop-helix) 0.0209309
TMED8 transmembrane emp24 protein transport domain containing 8 0.0208599
MLEC malectin 0.0208531
CRYBG1 crystallin beta-gamma domain containing 1 0.0208258
GPC6 glypican 6 0.0207873
CSAD cysteine sulfinic acid decarboxylase 0.0207343
ARSG arylsulfatase G 0.0206477
CXXC5 CXXC finger protein 5 0.0205993
ITSN1 intersectin 1 (SH3 domain protein) 0.0205265
SRSF4 serine/arginine-rich splicing factor 4 0.0205169
GFRA1 GDNF family receptor alpha 1 0.0204671
SESTD1 SEC14 and spectrin domains 1 0.020184
ZCCHC7 zinc finger, CCHC domain containing 7 0.020125
NXNL2 nucleoredoxin-like 2 0.0200806
LMAN2 lectin, mannose-binding 2 0.0200636
PGPEP1 pyroglutamyl-peptidase I 0.0199794
PRKCH protein kinase C, eta 0.0199662
SF3B2 splicing factor 3b, subunit 2, 145kDa 0.0199189
PXDN peroxidasin 0.0199048
RBM26 RNA binding motif protein 26 0.0198176
REST RE1-silencing transcription factor 0.019806
STRBP spermatid perinuclear RNA binding protein 0.0196919
SS18 synovial sarcoma translocation, chromosome 18 0.0196195
TRERF1 transcriptional regulating factor 1 0.0195588
FIGN fidgetin 0.0194579
EPN2 epsin 2 0.0194439
PARVA parvin, alpha 0.0194436
FTH1 ferritin, heavy polypeptide 1 0.0193387
PCNX1 pecanex 1 0.019335
CSDE1 cold shock domain containing E1, RNA-binding 0.0192534
NELFCD negative elongation factor complex member C/D 0.0191459
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.0191193
YARS1 tyrosyl-tRNA synthetase 1 0.0191129
BCAS1 breast carcinoma amplified sequence 1 0.0190751
SETD2 SET domain containing 2 0.0190123
SAFB2 scaffold attachment factor B2 0.0189798
XBP1 X-box binding protein 1 0.0189075
DNASE1 deoxyribonuclease I 0.0188294
OSBPL9 oxysterol binding protein-like 9 0.0186882
RPL34 ribosomal protein L34 0.0185673
MUC16 mucin 16, cell surface associated 0.018458
EEIG1 estrogen-induced osteoclastogenesis regulator 1 0.0184489
SIPA1L2 signal-induced proliferation-associated 1 like 2 0.0184102
CLEC16A C-type lectin domain family 16, member A 0.0181387
DHCR7 7-dehydrocholesterol reductase 0.0181382
GSR glutathione reductase 0.0180808
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 0.0180525
ANKRD50 ankyrin repeat domain 50 0.018034
INO80D INO80 complex subunit D 0.0180303
PRKG1 protein kinase, cGMP-dependent, type I 0.0180175
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.0180172
EP400 E1A binding protein p400 0.0180119
FHIP1A FHF complex subunit HOOK interacting protein 1A 0.01781
SUGP2 SURP and G patch domain containing 2 0.0178053
AFDN afadin, adherens junction formation factor 0.0176129
CLDN7 claudin 7 0.0175973
ZNF43 zinc finger protein 43 0.0174831
TBCA tubulin folding cofactor A 0.0174776
VPS26C VPS26 endosomal protein sorting factor C 0.017433
PHTF2 putative homeodomain transcription factor 2 0.0174242
RNASE12 ribonuclease, RNase A family, 12 (non-active) 0.0173641
PLEKHA6 pleckstrin homology domain containing, family A member 6 0.0173254
SGMS1 sphingomyelin synthase 1 0.0173123
FAF1 Fas (TNFRSF6) associated factor 1 0.0172838
MBD5 methyl-CpG binding domain protein 5 0.0172574
SAPCD2 suppressor APC domain containing 2 0.0172101
GTF2IRD2B GTF2I repeat domain containing 2B 0.0172081
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 0.0172045
PRELID2 PRELI domain containing 2 0.0171624
GNA14 guanine nucleotide binding protein (G protein), alpha 14 0.0171615
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 0.0171385
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.0171064
PGR progesterone receptor 0.0170882
LATS1 large tumor suppressor kinase 1 0.0170717
TBX2 T-box 2 0.0169961
PRRC2C proline-rich coiled-coil 2C 0.0169797
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.0169652
TTLL10 tubulin tyrosine ligase-like family member 10 0.0169642
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0169565
GARNL3 GTPase activating Rap/RanGAP domain-like 3 0.0169424
PRPF3 pre-mRNA processing factor 3 0.0169293
USP34 ubiquitin specific peptidase 34 0.0168768
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.0168562
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 0.0168508
ARHGAP12 Rho GTPase activating protein 12 0.0168423
BACE1 beta-site APP-cleaving enzyme 1 0.0167615
SCARB2 scavenger receptor class B, member 2 0.0167171
PRKCE protein kinase C, epsilon 0.0166947
CHD1L chromodomain helicase DNA binding protein 1-like 0.0166672
KLHL36 kelch-like family member 36 0.0166023
SEC63 SEC63 homolog (S. cerevisiae) 0.0165719
SPATS2 spermatogenesis associated, serine-rich 2 0.0165689
COL12A1 collagen, type XII, alpha 1 0.0164952
RPL11 ribosomal protein L11 0.0164571
SLC16A6 solute carrier family 16, member 6 0.0164547
SH3D19 SH3 domain containing 19 0.0164484
PCDH7 protocadherin 7 0.0164428
PKP4 plakophilin 4 0.0163849
BRWD1 bromodomain and WD repeat domain containing 1 0.0163719
BSPRY B-box and SPRY domain containing 0.016339
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 0.0163357
LTAP1 lipid transport auxiliary protein 1 0.0163327
ASXL2 additional sex combs like transcriptional regulator 2 0.0163283
CD164 CD164 molecule, sialomucin 0.0162904
SDC4 syndecan 4 0.0162889
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 0.01627
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.0162159
KDM5A lysine (K)-specific demethylase 5A 0.0161958
CDC27 cell division cycle 27 0.016195
KATNIP katanin interacting protein 0.0161875
FHIT fragile histidine triad 0.0161798
TPST1 tyrosylprotein sulfotransferase 1 0.0161717
PCDHB16 protocadherin beta 16 0.0161068
TRIM33 tripartite motif containing 33 0.0160757
CYB5D2 cytochrome b5 domain containing 2 0.0160545
EIF4B eukaryotic translation initiation factor 4B 0.0159811
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) 0.0159347
PLCB4 phospholipase C, beta 4 0.0158844
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 0.0158564
EXT1 exostosin glycosyltransferase 1 0.0158534
BIRC6 baculoviral IAP repeat containing 6 0.0158448
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 0.0158246
AURKA aurora kinase A 0.015816
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 0.0158149
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.0157971
SYNGAP1 synaptic Ras GTPase activating protein 1 0.0157622
CROT carnitine O-octanoyltransferase 0.0157165
PPP1R13B protein phosphatase 1, regulatory subunit 13B 0.0156881
ESD esterase D 0.0156501
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.015632
TRIP12 thyroid hormone receptor interactor 12 0.0155869
KIDINS220 kinase D-interacting substrate, 220kDa 0.0155431
CTNND1 catenin (cadherin-associated protein), delta 1 0.0155228
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.0155171
GOLGA4 golgin A4 0.0155128
BABAM2 BRISC and BRCA1 A complex member 2 0.0154877
SARS2 seryl-tRNA synthetase 2, mitochondrial 0.0154298
TMED3 transmembrane emp24 protein transport domain containing 3 0.0153476
ELF2 E74-like factor 2 (ets domain transcription factor) 0.0153157
TJP1 tight junction protein 1 0.0152874
PCM1 pericentriolar material 1 0.0152701
HMBOX1 homeobox containing 1 0.0152511
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.0152282
STARD10 StAR-related lipid transfer (START) domain containing 10 0.0152225
FBXO11 F-box protein 11 0.0152065
PHKB phosphorylase kinase, beta 0.0151954
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.0151949
INTS6 integrator complex subunit 6 0.0151788
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.015173
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 0.0151397
BPTF bromodomain PHD finger transcription factor 0.0151104
PTPN2 protein tyrosine phosphatase, non-receptor type 2 0.015095
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 0.0150716
SIDT1 SID1 transmembrane family, member 1 0.0150474
ULK1 unc-51 like autophagy activating kinase 1 0.0150469
HOOK2 hook microtubule-tethering protein 2 0.0150328
TUFM Tu translation elongation factor, mitochondrial 0.0149511
RBM33 RNA binding motif protein 33 0.0149425
GPATCH2 G patch domain containing 2 0.0149339
CNTROB centrobin, centrosomal BRCA2 interacting protein 0.0149118
ZNF516 zinc finger protein 516 0.0148937
SUMF2 sulfatase modifying factor 2 0.0148934
ODF2 outer dense fiber of sperm tails 2 0.0148569
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 0.0148524
ARSD arylsulfatase D 0.0148269
THRAP3 thyroid hormone receptor associated protein 3 0.0147842
DTNBP1 dystrobrevin binding protein 1 0.0147669
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0147122
TNRC6C trinucleotide repeat containing 6C 0.0146778
LGALS12 lectin, galactoside-binding, soluble, 12 0.0146663
SCAPER S-phase cyclin A-associated protein in the ER 0.0146316
DENND5A DENN/MADD domain containing 5A 0.0146183
GCH1 GTP cyclohydrolase 1 0.0145927
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0145864
GLB1 galactosidase, beta 1 0.0145014
TNPO3 transportin 3 0.0144973
ADGRA3 adhesion G protein-coupled receptor A3 0.0144334
CHEK2 checkpoint kinase 2 0.0144315
PCSK2 proprotein convertase subtilisin/kexin type 2 0.0144224
TENT2 terminal nucleotidyltransferase 2 0.014421
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.0144164
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.0143984
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.0143557
SERINC3 serine incorporator 3 0.0143388
CDH18 cadherin 18, type 2 0.0143329
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 0.0143286
SCAF11 SR-related CTD-associated factor 11 0.0143028
TRAFD1 TRAF-type zinc finger domain containing 1 0.0142843
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 0.0142784
UBE3C ubiquitin protein ligase E3C 0.0142778
ARMC9 armadillo repeat containing 9 0.0142675
KDM5C lysine (K)-specific demethylase 5C 0.0142658
RAD9A RAD9 homolog A (S. pombe) 0.0142441
FUBP3 far upstream element (FUSE) binding protein 3 0.0141842
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.0141407
OLA1 Obg-like ATPase 1 0.0141313
DGKE diacylglycerol kinase, epsilon 64kDa 0.0141136
BRD3 bromodomain containing 3 0.0140593
MXD4 MAX dimerization protein 4 0.0140426
MIDN midnolin 0.0140123
ELP2 elongator acetyltransferase complex subunit 2 0.0140087
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0139619
CEP350 centrosomal protein 350kDa 0.0139617
ERMP1 endoplasmic reticulum metallopeptidase 1 0.0138935
ANKRD28 ankyrin repeat domain 28 0.0138932
RAD17 RAD17 homolog (S. pombe) 0.0138814
ERLEC1 endoplasmic reticulum lectin 1 0.0138552
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.013839
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 0.0137965
SSH1 slingshot protein phosphatase 1 0.0137847
KIF13A kinesin family member 13A 0.0137841
STIM1 stromal interaction molecule 1 0.0137568
H2BC5 H2B clustered histone 5 0.0137416
OTUD7B OTU deubiquitinase 7B 0.0137409
CCAR1 cell division cycle and apoptosis regulator 1 0.0137367
TPX2 TPX2, microtubule-associated 0.0137225
NOD1 nucleotide-binding oligomerization domain containing 1 0.0137133
GDF15 growth differentiation factor 15 0.0136922
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 0.0136754
STX5 syntaxin 5 0.013674
RUFY1 RUN and FYVE domain containing 1 0.0136381
IPMK inositol polyphosphate multikinase 0.0136369
TMX4 thioredoxin-related transmembrane protein 4 0.0136324
ANKIB1 ankyrin repeat and IBR domain containing 1 0.0135421
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 0.0135286
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0135272
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0135041
TRAPPC10 trafficking protein particle complex 10 0.0135003
ARID5B AT rich interactive domain 5B (MRF1-like) 0.013475
PGCKA1 PDCD10 and GCKIII kinases associated 1 0.0134538
LGALS3 lectin, galactoside-binding, soluble, 3 0.0134466
ABHD17B abhydrolase domain containing 17B 0.0134147
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0134024
CDK12 cyclin-dependent kinase 12 0.013391
CDK8 cyclin-dependent kinase 8 0.0133853
TASOR transcription activation suppressor 0.0133615
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0133584
RNF13 ring finger protein 13 0.0133208
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.0133197
SPOP speckle-type POZ protein 0.0133195
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 0.0133163
SQLE squalene epoxidase 0.0133141
NCOA2 nuclear receptor coactivator 2 0.0132752
PLEKHA7 pleckstrin homology domain containing, family A member 7 0.0132745
MREG melanoregulin 0.0132607
EXOC4 exocyst complex component 4 0.0131856
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.013185
NUCB2 nucleobindin 2 0.0131558
PRCC papillary renal cell carcinoma (translocation-associated) 0.0131553
D2HGDH D-2-hydroxyglutarate dehydrogenase 0.0131264
CPEB3 cytoplasmic polyadenylation element binding protein 3 0.0131164
VAV3 vav 3 guanine nucleotide exchange factor 0.013057
ASXL1 additional sex combs like transcriptional regulator 1 0.0130313
PEX11A peroxisomal biogenesis factor 11 alpha 0.0129844
SPTSSA serine palmitoyltransferase, small subunit A 0.0129571
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.0129085
WDR45B WD repeat domain 45B 0.0129035
BCLAF3 BCLAF1 and THRAP3 family member 3 0.0128763
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) 0.0128697
LMNB2 lamin B2 0.0128493
ZNF100 zinc finger protein 100 0.0128468
TM9SF2 transmembrane 9 superfamily member 2 0.0128384
ARID4B AT rich interactive domain 4B (RBP1-like) 0.0128228
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains 0.0128179
SNX29 sorting nexin 29 0.0127832
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 0.0127601
RDX radixin 0.0127547
ZFP14 ZFP14 zinc finger protein 0.0127229
IRX2 iroquois homeobox 2 0.0126999
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae) 0.0126811
SNF8 SNF8, ESCRT-II complex subunit 0.0126737
CDC5L cell division cycle 5-like 0.0126642
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 0.0125856
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.0124892
ACBD3 acyl-CoA binding domain containing 3 0.0124861
SEC13 SEC13 homolog (S. cerevisiae) 0.0124744
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.0124733
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 0.0124536
EAPP E2F-associated phosphoprotein 0.0124346
ZNF91 zinc finger protein 91 0.0123981
DPH6 diphthamine biosynthesis 6 0.0123951
COX6C cytochrome c oxidase subunit VIc 0.0123822
H3C4 H3 clustered histone 4 0.0123512
ZFHX3 zinc finger homeobox 3 0.0123388
EXOC5 exocyst complex component 5 0.0123274
MAPK10 mitogen-activated protein kinase 10 0.0123015
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.0122885
ATXN3 ataxin 3 0.012279
DENND4C DENN/MADD domain containing 4C 0.0122522
YME1L1 YME1-like 1 ATPase 0.0122395
FBP1 fructose-1,6-bisphosphatase 1 0.0122382
SAMD12 sterile alpha motif domain containing 12 0.0122381
NAV1 neuron navigator 1 0.012234
MSL1 male-specific lethal 1 homolog (Drosophila) 0.0122235
SLC38A9 solute carrier family 38, member 9 0.0122102
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 0.0121984
IRF2BPL interferon regulatory factor 2 binding protein-like 0.0121718
SIVA1 SIVA1, apoptosis-inducing factor 0.0121472
WIPI1 WD repeat domain, phosphoinositide interacting 1 0.0121357
SLU7 SLU7 splicing factor homolog (S. cerevisiae) 0.0121347
ALDH16A1 aldehyde dehydrogenase 16 family, member A1 0.0121175
STAU2 staufen double-stranded RNA binding protein 2 0.012117
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.0121119
ACOX1 acyl-CoA oxidase 1, palmitoyl 0.012105
NOXRED1 NADP-dependent oxidoreductase domain containing 1 0.0120852
TAC4 tachykinin 4 (hemokinin) 0.0120756
ERCC6L2 excision repair cross-complementation group 6-like 2 0.0120691
ZNF148 zinc finger protein 148 0.0120472
SLC7A6OS solute carrier family 7, member 6 opposite strand 0.0120417
COL21A1 collagen, type XXI, alpha 1 0.012026
SFXN4 sideroflexin 4 0.0120153
ITPRID2 ITPR interacting domain containing 2 0.0120152
S100A14 S100 calcium binding protein A14 0.0119942
NUBPL nucleotide binding protein-like 0.0119899
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.0119682
MRPS18B mitochondrial ribosomal protein S18B 0.0119587
CFAP44 cilia and flagella associated protein 44 0.0119558
EPHA6 EPH receptor A6 0.0119556
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) 0.0119507
C1ORF21 chromosome 1 open reading frame 21 0.0119298
GIGYF2 GRB10 interacting GYF protein 2 0.0119286
TADA3 transcriptional adaptor 3 0.0119107
SORT1 sortilin 1 0.0118901
ATXN7L1 ataxin 7-like 1 0.0118813
CABIN1 calcineurin binding protein 1 0.0118747
OXCT1 3-oxoacid CoA transferase 1 0.0118401
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 0.0118001
RPL36 ribosomal protein L36 0.0117982
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 0.0117949
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.0117937
ACSS2 acyl-CoA synthetase short-chain family member 2 0.0117768
ZFP91 ZFP91 zinc finger protein 0.011775
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 0.0117704
NOVA1 neuro-oncological ventral antigen 1 0.0117571
HIBADH 3-hydroxyisobutyrate dehydrogenase 0.0117494
CCDC148 coiled-coil domain containing 148 0.0117433
BCAS4 breast carcinoma amplified sequence 4 0.0117376
ATP11B ATPase, class VI, type 11B 0.0117083
UBE3A ubiquitin protein ligase E3A 0.0117074
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.011686
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 0.0116854
RPL18A ribosomal protein L18a 0.011667
RBMS1 RNA binding motif, single stranded interacting protein 1 0.0116001
DCAF6 DDB1 and CUL4 associated factor 6 0.0115944
KIAA1217 KIAA1217 0.0115746
P3H1 prolyl 3-hydroxylase 1 0.0115649
TRAPPC9 trafficking protein particle complex 9 0.0115623
DAND5 DAN domain family member 5, BMP antagonist 0.0115505
ANXA9 annexin A9 0.0115505
OTUD6B OTU domain containing 6B 0.0115435

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.188975
IFI6 interferon, alpha-inducible protein 6 -0.11831
TPM4 tropomyosin 4 -0.106526
TFF1 trefoil factor 1 -0.0960921
RPLP1 ribosomal protein, large, P1 -0.0933366
MED13L mediator complex subunit 13-like -0.0906786
AGR2 anterior gradient 2 -0.0856037
BMP7 bone morphogenetic protein 7 -0.0830673
PKM pyruvate kinase, muscle -0.0827173
ACTG1 actin gamma 1 -0.0799534
MRPL13 mitochondrial ribosomal protein L13 -0.0700105
PRR11 proline rich 11 -0.0673317
ENO1 enolase 1, (alpha) -0.0659109
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -0.064221
FLNA filamin A, alpha -0.0619278
TUBA1B tubulin, alpha 1b -0.0595377
RPLP0 ribosomal protein, large, P0 -0.0577119
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0576861
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0566518
DSCAM Down syndrome cell adhesion molecule -0.0563236
RPL8 ribosomal protein L8 -0.0525234
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -0.0524483
LOC112694756 uncharaterized LOC112694756 -0.0522551
CLTC clathrin, heavy chain (Hc) -0.0516468
RPS29 ribosomal protein S29 -0.0508456
NRIP1 nuclear receptor interacting protein 1 -0.0506222
GSE1 Gse1 coiled-coil protein -0.0505602
ATAD2 ATPase family, AAA domain containing 2 -0.049039
CAPZB capping protein (actin filament) muscle Z-line, beta -0.0484
RPL30 ribosomal protein L30 -0.0481466
KRT19 keratin 19, type I -0.0480997
IFI27 interferon, alpha-inducible protein 27 -0.048042
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0478143
H3-3B H3.3 histone B -0.047753
TOP1 topoisomerase (DNA) I -0.0463702
JUP junction plakoglobin -0.0462637
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0458084
RPS3 ribosomal protein S3 -0.0457721
EPHA4 EPH receptor A4 -0.0453415
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0451631
POTEF POTE ankyrin domain family, member F -0.0447894
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.0444378
SULF2 sulfatase 2 -0.0442252
MACF1 microtubule-actin crosslinking factor 1 -0.0439538
RPS18 ribosomal protein S18 -0.0438267
GRB2 growth factor receptor-bound protein 2 -0.0437627
RPL10A ribosomal protein L10a -0.0435051
RPL12 ribosomal protein L12 -0.0431329
RPS6 ribosomal protein S6 -0.0423831
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed -0.0420645
MKI67 marker of proliferation Ki-67 -0.0409362
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.040531
RPL28 ribosomal protein L28 -0.0395194
LRIF1 ligand dependent nuclear receptor interacting factor 1 -0.0390739
MAP3K20 mitogen-activated protein kinase kinase kinase 20 -0.0386935
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0386544
PLEC plectin -0.0381548
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0376543
RPS5 ribosomal protein S5 -0.0375744
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0374759
LYPD6B LY6/PLAUR domain containing 6B -0.0372963
GNPDA1 glucosamine-6-phosphate deaminase 1 -0.0368364
PTPRF protein tyrosine phosphatase, receptor type, F -0.0367608
HSPB1 heat shock 27kDa protein 1 -0.0367024
ADNP activity-dependent neuroprotector homeobox -0.0363472
TET2 tet methylcytosine dioxygenase 2 -0.0360337
DSTN destrin (actin depolymerizing factor) -0.035838
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -0.0353841
PTK2 protein tyrosine kinase 2 -0.0351347
RPS9 ribosomal protein S9 -0.0347919
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.034435
MRTFA myocardin related transcription factor A -0.0344114
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -0.0341676
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 -0.0341664
PTGES3 prostaglandin E synthase 3 (cytosolic) -0.0341416
SMYD3 SET and MYND domain containing 3 -0.0341069
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0338428
VAV2 vav 2 guanine nucleotide exchange factor -0.0333747
SPAG9 sperm associated antigen 9 -0.0333641
VMP1 vacuole membrane protein 1 -0.0333521
SEC11A SEC11 homolog A (S. cerevisiae) -0.0330891
DLG5 discs, large homolog 5 (Drosophila) -0.0329075
FOXP1 forkhead box P1 -0.0328276
PTEN phosphatase and tensin homolog -0.0326891
PBX3 pre-B-cell leukemia homeobox 3 -0.032649
SETD5 SET domain containing 5 -0.0325193
RPS14 ribosomal protein S14 -0.0324986
SERINC5 serine incorporator 5 -0.0324412
SMC4 structural maintenance of chromosomes 4 -0.0323836
TGFB2 transforming growth factor, beta 2 -0.0322144
RAB31 RAB31, member RAS oncogene family -0.0320815
SDK1 sidekick cell adhesion molecule 1 -0.0319359
UBB ubiquitin B -0.0317162
TMEM150C transmembrane protein 150C -0.0316832
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like -0.0310217
PTPRE protein tyrosine phosphatase, receptor type, E -0.0307873
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0306295
LDLR low density lipoprotein receptor -0.030462
MYH9 myosin, heavy chain 9, non-muscle -0.0302719
TNPO1 transportin 1 -0.0298311
KDM2A lysine (K)-specific demethylase 2A -0.0297014
TPI1 triosephosphate isomerase 1 -0.0296709
ATP5F1E ATP synthase F1 subunit epsilon -0.0294814
RPL13A ribosomal protein L13a -0.0291166
ATP9A ATPase, class II, type 9A -0.0288972
RANBP17 RAN binding protein 17 -0.0288624
UTRN utrophin -0.0288166
TPM3 tropomyosin 3 -0.0287538
MYO16 myosin XVI -0.0285196
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -0.0283588
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.0282255
ANXA2 annexin A2 -0.0281103
LPP LIM domain containing preferred translocation partner in lipoma -0.0280947
GLG1 golgi glycoprotein 1 -0.0279989
SNX6 sorting nexin 6 -0.0278487
LMNA lamin A/C -0.0277656
ARL15 ADP-ribosylation factor-like 15 -0.0276998
ZNF292 zinc finger protein 292 -0.0276987
REPS1 RALBP1 associated Eps domain containing 1 -0.0275931
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -0.0275579
IVD isovaleryl-CoA dehydrogenase -0.0275292
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -0.0275249
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0275106
PACS1 phosphofurin acidic cluster sorting protein 1 -0.02745
RAB10 RAB10, member RAS oncogene family -0.0272341
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0272087
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.027203
COPE coatomer protein complex, subunit epsilon -0.0270829
PPP1R12A protein phosphatase 1, regulatory subunit 12A -0.0269257
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0267537
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -0.0266784
CYRIB CYFIP related Rac1 interactor B -0.0266403
CLSTN1 calsyntenin 1 -0.0265777
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 -0.0265759
EXOC6B exocyst complex component 6B -0.0261472
RPL39 ribosomal protein L39 -0.0259344
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0257237
RNF168 ring finger protein 168, E3 ubiquitin protein ligase -0.0256914
SON SON DNA binding protein -0.0254502
ATP5F1B ATP synthase F1 subunit beta -0.0254311
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0253492
RPL29 ribosomal protein L29 -0.0253106
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 -0.0252347
CALR calreticulin -0.0252337
TIAM1 T-cell lymphoma invasion and metastasis 1 -0.0252078
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0251469
SH3RF1 SH3 domain containing ring finger 1 -0.0249238
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.0248813
EPCAM epithelial cell adhesion molecule -0.0248232
RPS25 ribosomal protein S25 -0.0247455
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0247138
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase -0.0247102
PAN3 PAN3 poly(A) specific ribonuclease subunit -0.0246872
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -0.0245527
ESRP1 epithelial splicing regulatory protein 1 -0.0245153
DLG1 discs, large homolog 1 (Drosophila) -0.0244545
TPM1 tropomyosin 1 (alpha) -0.0243448
MYO1B myosin IB -0.024179
HIPK2 homeodomain interacting protein kinase 2 -0.024174
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 -0.0241686
PPP4R3B protein phosphatase 4 regulatory subunit 3B -0.0241339
THBS1 thrombospondin 1 -0.0241143
PDS5A PDS5 cohesin associated factor A -0.0240753
ADCY9 adenylate cyclase 9 -0.0240417
COPB1 coatomer protein complex, subunit beta 1 -0.0239124
RPL38 ribosomal protein L38 -0.0237928
GLO1 glyoxalase I -0.023788
CLASP1 cytoplasmic linker associated protein 1 -0.0237048
BST2 bone marrow stromal cell antigen 2 -0.023607
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0235404
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -0.0234262
HM13 histocompatibility (minor) 13 -0.0233552
RPL7A ribosomal protein L7a -0.0233416
FGF12 fibroblast growth factor 12 -0.0233383
RPL15 ribosomal protein L15 -0.0233114
UBE4A ubiquitination factor E4A -0.0232628
EIF1 eukaryotic translation initiation factor 1 -0.0232223
DAAM1 dishevelled associated activator of morphogenesis 1 -0.023186
CANX calnexin -0.0231513
UBA1 ubiquitin-like modifier activating enzyme 1 -0.0229898
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0229572
EML4 echinoderm microtubule associated protein like 4 -0.0229554
UBTF upstream binding transcription factor, RNA polymerase I -0.0228581
RPS2 ribosomal protein S2 -0.0227526
EIF3B eukaryotic translation initiation factor 3, subunit B -0.0226227
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.022309
APRT adenine phosphoribosyltransferase -0.0223054
RPS19 ribosomal protein S19 -0.0222595
SIPA1L1 signal-induced proliferation-associated 1 like 1 -0.0222469
ATG7 autophagy related 7 -0.0222193
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -0.0221684
PTPRK protein tyrosine phosphatase, receptor type, K -0.0220669
MTSS1 metastasis suppressor 1 -0.0220028
SKA2 spindle and kinetochore associated complex subunit 2 -0.0218952
ARID1A AT rich interactive domain 1A (SWI-like) -0.0217531
UBE2D3 ubiquitin-conjugating enzyme E2D 3 -0.0217011
MCM4 minichromosome maintenance complex component 4 -0.0216738
SINHCAF SIN3-HDAC complex associated factor -0.0215585
TFRC transferrin receptor -0.021455
UBC ubiquitin C -0.0214516
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -0.021437
CMC2 C-x(9)-C motif containing 2 -0.021412
AGO2 argonaute RISC catalytic component 2 -0.0213727
RPS16 ribosomal protein S16 -0.0213095
TMEM120B transmembrane protein 120B -0.0212813
RHEB Ras homolog enriched in brain -0.0212356
SVIL supervillin -0.0211617
RALY RALY heterogeneous nuclear ribonucleoprotein -0.0211161
PFN1 profilin 1 -0.0210423
BAZ1A bromodomain adjacent to zinc finger domain, 1A -0.0210398
TUBB tubulin, beta class I -0.0210353
AP1G1 adaptor-related protein complex 1, gamma 1 subunit -0.0210294
RAB21 RAB21, member RAS oncogene family -0.0210282
KPNA6 karyopherin alpha 6 (importin alpha 7) -0.0210048
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 -0.0210002
EXOC2 exocyst complex component 2 -0.0209938
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0209691
SELENOI selenoprotein I -0.0209633
GCC2 GRIP and coiled-coil domain containing 2 -0.0209375
LRPPRC leucine-rich pentatricopeptide repeat containing -0.0209189
TAPBP TAP binding protein (tapasin) -0.0209149
RPL19 ribosomal protein L19 -0.0208942
RPL37A ribosomal protein L37a -0.0208496
DLC1 DLC1 Rho GTPase activating protein -0.0208443
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -0.0208257
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 -0.0208109
ZNF124 zinc finger protein 124 -0.0207873
RPL35A ribosomal protein L35a -0.0207316
PALLD palladin, cytoskeletal associated protein -0.0205864
H1-10 H1.10 linker histone -0.0205117
RPL7L1 ribosomal protein L7-like 1 -0.0205067
AKAP9 A kinase (PRKA) anchor protein 9 -0.0204966
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 -0.0204937
CLIC4 chloride intracellular channel 4 -0.0204163
ADAT1 adenosine deaminase, tRNA-specific 1 -0.0203746
HNRNPF heterogeneous nuclear ribonucleoprotein F -0.0202603
PICALM phosphatidylinositol binding clathrin assembly protein -0.0202489
PHB2 prohibitin 2 -0.0202456
TRIM44 tripartite motif containing 44 -0.020154
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) -0.0200442
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 -0.02004
NHP2 NHP2 ribonucleoprotein -0.0200343
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -0.0197719
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -0.0197658
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.0197172
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.0196633
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -0.019634
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -0.0195767
FANCI Fanconi anemia, complementation group I -0.0195557
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -0.0194973
RAP1B RAP1B, member of RAS oncogene family -0.0194675
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0194225
MPDU1 mannose-P-dolichol utilization defect 1 -0.0193917
KIF14 kinesin family member 14 -0.0193909
RHOC ras homolog family member C -0.0192916
GPATCH2L G patch domain containing 2-like -0.0192891
SAP30BP SAP30 binding protein -0.0192773
MYADM myeloid-associated differentiation marker -0.0192608
CHLSN cholesin -0.0191975
CALU calumenin -0.0191946
AK7 adenylate kinase 7 -0.019119
EEF2 eukaryotic translation elongation factor 2 -0.0190887
TTC19 tetratricopeptide repeat domain 19 -0.0190856
SMAD3 SMAD family member 3 -0.0190377
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 -0.0189578
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -0.0189221
RPS8 ribosomal protein S8 -0.0189031
NFX1 nuclear transcription factor, X-box binding 1 -0.0188553
PDLIM5 PDZ and LIM domain 5 -0.018841
TUG1 taurine up-regulated 1 (non-protein coding) -0.0188067
TRIM27 tripartite motif containing 27 -0.0188018
ARID1B AT rich interactive domain 1B (SWI1-like) -0.0187307
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -0.0187236
CTNND2 catenin (cadherin-associated protein), delta 2 -0.0186757
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0186124
HEATR6 HEAT repeat containing 6 -0.018595
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0185873
ANKRD13C ankyrin repeat domain 13C -0.0185658
YY1 YY1 transcription factor -0.0185637
L2HGDH L-2-hydroxyglutarate dehydrogenase -0.01852
PER2 period circadian clock 2 -0.0185066
FOXO1 forkhead box O1 -0.018498
CHD9 chromodomain helicase DNA binding protein 9 -0.0184652
VDAC2 voltage-dependent anion channel 2 -0.0184538
TM7SF3 transmembrane 7 superfamily member 3 -0.0184304
CENPP centromere protein P -0.0184114
WEE1 WEE1 G2 checkpoint kinase -0.0183957
KIF3B kinesin family member 3B -0.0183931
RPS12 ribosomal protein S12 -0.0183775
HLTF helicase-like transcription factor -0.0183687
THOC7 THO complex 7 -0.0183255
GDI2 GDP dissociation inhibitor 2 -0.0183159
RMDN1 regulator of microtubule dynamics 1 -0.0182345
CDK13 cyclin-dependent kinase 13 -0.0182294
MDM4 MDM4, p53 regulator -0.0182088
GON4L gon-4-like (C. elegans) -0.0181849
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 -0.018101
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -0.0180957
SYNGR2 synaptogyrin 2 -0.0180489
HEATR5B HEAT repeat containing 5B -0.0180309
IPO7 importin 7 -0.0179961
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.0179939
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 -0.017978
PRPF8 pre-mRNA processing factor 8 -0.0179706
ITPKC inositol-trisphosphate 3-kinase C -0.0179678
SEPTIN7 septin 7 -0.0179605
CAMKMT calmodulin-lysine N-methyltransferase -0.0179559
SETX senataxin -0.0178677
SDCCAG8 serologically defined colon cancer antigen 8 -0.0178582
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0178314
CMSS1 cms1 ribosomal small subunit homolog (yeast) -0.017817
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -0.0178141
ADAM15 ADAM metallopeptidase domain 15 -0.0177538
RAD21 RAD21 homolog (S. pombe) -0.0177289
SENP6 SUMO1/sentrin specific peptidase 6 -0.0177276
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.0177175
TAOK3 TAO kinase 3 -0.0177043
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -0.0176573
KMT2E lysine (K)-specific methyltransferase 2E -0.0176513
RPLP2 ribosomal protein, large, P2 -0.0175728
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -0.0175393
FANCC Fanconi anemia, complementation group C -0.0175309
KRT80 keratin 80, type II -0.0175286
NECTIN2 nectin cell adhesion molecule 2 -0.0174801
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -0.0174593
NCAPD2 non-SMC condensin I complex, subunit D2 -0.0174358
ATE1 arginyltransferase 1 -0.0174346
ADD1 adducin 1 (alpha) -0.0174271
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) -0.0174256
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -0.0174191
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -0.0174012
DTNB dystrobrevin, beta -0.01739
PPP1R7 protein phosphatase 1, regulatory subunit 7 -0.017389
AREG amphiregulin -0.0173839
DPP8 dipeptidyl-peptidase 8 -0.0173433
CDC37 cell division cycle 37 -0.0173238
ANXA4 annexin A4 -0.0173165
FOXK1 forkhead box K1 -0.0172985
ANO10 anoctamin 10 -0.0172191
STK10 serine/threonine kinase 10 -0.0171932
FAM177A1 family with sequence similarity 177, member A1 -0.017145
HELZ helicase with zinc finger -0.0171155
SREBF2 sterol regulatory element binding transcription factor 2 -0.0171084
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -0.0170999
FTO fat mass and obesity associated -0.0169539
DNASE2 deoxyribonuclease II, lysosomal -0.0169287
ARL8B ADP-ribosylation factor-like 8B -0.0168926
MAU2 MAU2 sister chromatid cohesion factor -0.016837
UBA2 ubiquitin-like modifier activating enzyme 2 -0.0168299
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 -0.0168249
EXOC6 exocyst complex component 6 -0.0168202
ACTN1 actinin, alpha 1 -0.0168123
DSG2 desmoglein 2 -0.0168056
EZR ezrin -0.0167864
BRCA1 breast cancer 1, early onset -0.0167854
GMCL1 germ cell-less, spermatogenesis associated 1 -0.0167807
FNDC3B fibronectin type III domain containing 3B -0.0167762
ALKBH5 AlkB family member 5, RNA demethylase -0.0167726
FAM174B family with sequence similarity 174, member B -0.0167659
RORA RAR-related orphan receptor A -0.0167432
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 -0.01674
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -0.0167207
SYNJ2BP synaptojanin 2 binding protein -0.016661
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0165688
RBPMS RNA binding protein with multiple splicing -0.0164976
NCKAP1 NCK-associated protein 1 -0.0164784
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -0.0164751
SPPL2A signal peptide peptidase like 2A -0.0164413
XPO1 exportin 1 -0.0164012
CD9 CD9 molecule -0.0163703
KIF23 kinesin family member 23 -0.0163659
RBM6 RNA binding motif protein 6 -0.016319
PPP4R3A protein phosphatase 4 regulatory subunit 3A -0.0162583
GPBP1 GC-rich promoter binding protein 1 -0.0162338
MYO5A myosin VA (heavy chain 12, myoxin) -0.0162325
HDGFL3 HDGF like 3 -0.0162008
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 -0.0161683
YBX1 Y box binding protein 1 -0.0161298
NF1 neurofibromin 1 -0.0161097
PSD3 pleckstrin and Sec7 domain containing 3 -0.0160915
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 -0.0160579
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.0160573
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 -0.0160133
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha -0.0159971
LNPEP leucyl/cystinyl aminopeptidase -0.0159582
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.0159576
MPHOSPH8 M-phase phosphoprotein 8 -0.0159411
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -0.0158989
ARHGAP10 Rho GTPase activating protein 10 -0.0158484
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 -0.015827
SF3B3 splicing factor 3b, subunit 3, 130kDa -0.0158114
FAM168B family with sequence similarity 168, member B -0.015793
CCND1 cyclin D1 -0.0157748
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -0.0157652
IFITM3 interferon induced transmembrane protein 3 -0.0157555
CPT1A carnitine palmitoyltransferase 1A (liver) -0.0157409
MYO1D myosin ID -0.0157216
ZNF217 zinc finger protein 217 -0.0157141
ZSWIM5 zinc finger, SWIM-type containing 5 -0.015687
NUDC nudC nuclear distribution protein -0.0156692
MAP3K7 mitogen-activated protein kinase kinase kinase 7 -0.0156557
RPS11 ribosomal protein S11 -0.0156187
PCGF6 polycomb group ring finger 6 -0.0155813
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -0.0155598
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1 -0.015558
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -0.0155571
CSNK1G1 casein kinase 1, gamma 1 -0.015535
RNF216 ring finger protein 216 -0.0155254
HELZ2 helicase with zinc finger 2, transcriptional coactivator -0.0155194
DPP9 dipeptidyl-peptidase 9 -0.0155039
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) -0.0154881
ZC3H8 zinc finger CCCH-type containing 8 -0.0154632
FBXO28 F-box protein 28 -0.0154125
AK1 adenylate kinase 1 -0.015341
KCMF1 potassium channel modulatory factor 1 -0.0153324
EIF3J eukaryotic translation initiation factor 3, subunit J -0.0152989
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.0152746
RNASE3 ribonuclease, RNase A family, 3 -0.0152684
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0152664
SH3BP5 SH3-domain binding protein 5 (BTK-associated) -0.0152148
DCAF7 DDB1 and CUL4 associated factor 7 -0.0152126
DENR density-regulated protein -0.015172
UTP4 UTP4 small subunit processome component -0.0151641
RPRD1B regulation of nuclear pre-mRNA domain containing 1B -0.0151544
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) -0.0151194
CDK17 cyclin-dependent kinase 17 -0.0150857
CNOT9 CCR4-NOT transcription complex subunit 9 -0.0150724
CERT1 ceramide transporter 1 -0.0150667
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0150617
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -0.0150136
ITGAV integrin, alpha V -0.014983
ILF3 interleukin enhancer binding factor 3, 90kDa -0.0149646
KNTC1 kinetochore associated 1 -0.0149568
CACUL1 CDK2-associated, cullin domain 1 -0.0149316
CTSA cathepsin A -0.0149073
ZNF251 zinc finger protein 251 -0.0148668
IWS1 IWS1 homolog (S. cerevisiae) -0.0148475
EIF3H eukaryotic translation initiation factor 3, subunit H -0.0148221
WDPCP WD repeat containing planar cell polarity effector -0.0148194
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 -0.0148182
HSPA8 heat shock 70kDa protein 8 -0.0148173
RRM1 ribonucleotide reductase M1 -0.0148052
RPTOR regulatory associated protein of MTOR, complex 1 -0.0147954
SACK1H scaffolding CK1 anchoring protein H -0.0147652
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 -0.0147619
HAUS6 HAUS augmin-like complex, subunit 6 -0.0147604
ADI1 acireductone dioxygenase 1 -0.0147566
STK38L serine/threonine kinase 38 like -0.0147334
WDR47 WD repeat domain 47 -0.0147291
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 -0.0147218
ZC3H7A zinc finger CCCH-type containing 7A -0.0147066
CD81 CD81 molecule -0.014676
MACC1 metastasis associated in colon cancer 1 -0.0146633
IQCN IQ motif containing N -0.014653
ISG15 ISG15 ubiquitin-like modifier -0.0146514
MIDEAS mitotic deacetylase associated SANT domain protein -0.0146473
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha -0.0146057
UBAP2L ubiquitin associated protein 2-like -0.0145972
RNF130 ring finger protein 130 -0.0145805
ARHGAP5 Rho GTPase activating protein 5 -0.0145223
RPL17-C18ORF32 RPL17-C18orf32 readthrough -0.0145054
WARS1 tryptophanyl-tRNA synthetase 1 -0.0144943
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0144844
TUBB4B tubulin, beta 4B class IVb -0.014482
WNK1 WNK lysine deficient protein kinase 1 -0.0144796
MCM7 minichromosome maintenance complex component 7 -0.0144765
BTBD1 BTB (POZ) domain containing 1 -0.0144584
CXORF38 chromosome X open reading frame 38 -0.0143489
MYH14 myosin, heavy chain 14, non-muscle -0.0143355
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.0143253
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) -0.0143092
COQ10B coenzyme Q10 homolog B (S. cerevisiae) -0.0143029
RNF149 ring finger protein 149 -0.0142716
ZER1 zyg-11 related, cell cycle regulator -0.0142584
METTL2A methyltransferase like 2A -0.0142464
TTF1 transcription termination factor, RNA polymerase I -0.0142449
PFKL phosphofructokinase, liver -0.0142317
CHD6 chromodomain helicase DNA binding protein 6 -0.0141812
CDC42 cell division cycle 42 -0.014174
STIP1 stress-induced phosphoprotein 1 -0.0141585
EEF2K eukaryotic elongation factor 2 kinase -0.0141306
NEBL nebulette -0.0141282
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.0141237
NBPF11 neuroblastoma breakpoint family, member 11 -0.0140747
MECP2 methyl CpG binding protein 2 -0.0140711
CAMK1D calcium/calmodulin-dependent protein kinase ID -0.0140682
RPS7 ribosomal protein S7 -0.0140507
TBCD tubulin folding cofactor D -0.0140302
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.0140089
HAT1 histone acetyltransferase 1 -0.0140038
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -0.0140037
RPS24 ribosomal protein S24 -0.0139962
LDHA lactate dehydrogenase A -0.0139829
CSNK1A1 casein kinase 1, alpha 1 -0.0139787
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 -0.013977
NEO1 neogenin 1 -0.0139693
EPHB4 EPH receptor B4 -0.0139579
RBM4 RNA binding motif protein 4 -0.0139568
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) -0.0139487
SLC35E1 solute carrier family 35, member E1 -0.0139451