MCM5 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description minichromosome maintenance complex component 5|The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4174)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_MCM5
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Genes

61 co-expressed genes for MCM5 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
CDCA8 cell division cycle associated 8
CENPM centromere protein M
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
DEK DEK proto-oncogene
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DKC1 dyskeratosis congenita 1, dyskerin
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DUT deoxyuridine triphosphatase
EED embryonic ectoderm development
EXOSC8 exosome component 8
FEN1 flap structure-specific endonuclease 1
GINS1 GINS complex subunit 1 (Psf1 homolog)
GINS2 GINS complex subunit 2 (Psf2 homolog)
HAT1 histone acetyltransferase 1
HMGB2 high mobility group box 2
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSPB11 heat shock protein family B (small), member 11
LAS1L LAS1-like (S. cerevisiae)
LMNB1 lamin B1
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM4 minichromosome maintenance complex component 4
MCM5 minichromosome maintenance complex component 5
MCM7 minichromosome maintenance complex component 7
MCUR1 mitochondrial calcium uniporter regulator 1
NASP nuclear autoantigenic sperm protein (histone-binding)
NDC80 NDC80 kinetochore complex component
NOP14 NOP14 nucleolar protein
NOP56 NOP56 ribonucleoprotein
NUP153 nucleoporin 153kDa
NUP62 nucleoporin 62kDa
PA2G4 proliferation-associated 2G4, 38kDa
PCNA proliferating cell nuclear antigen
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
PTBP1 polypyrimidine tract binding protein 1
RBMX RNA binding motif protein, X-linked
RRM1 ribonucleotide reductase M1
SERBP1 SERPINE1 mRNA binding protein 1
SF3B3 splicing factor 3b, subunit 3, 130kDa
SFPQ splicing factor proline/glutamine-rich
SLBP stem-loop binding protein
SMC1A structural maintenance of chromosomes 1A
SMC4 structural maintenance of chromosomes 4
SNRPG small nuclear ribonucleoprotein polypeptide G
SRI sorcin
SRSF1 serine/arginine-rich splicing factor 1
SSRP1 structure specific recognition protein 1
SUZ12 SUZ12 polycomb repressive complex 2 subunit
TOP2A topoisomerase (DNA) II alpha 170kDa
TOPBP1 topoisomerase (DNA) II binding protein 1
TRA2B transformer 2 beta homolog (Drosophila)
TYMS thymidylate synthetase
U2SURP U2 snRNP-associated SURP domain containing
USP1 ubiquitin specific peptidase 1
VRK1 vaccinia related kinase 1
WDR61 WD repeat domain 61
ZWINT ZW10 interacting kinetochore protein