| Dataset | GO Biological Process Annotations 2025 |
| Category | structural or functional annotations |
| Type | biological process |
| Description | Any series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA. MDA-5 detects RNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines. (Gene Ontology, GO_0039530) |
| External Link | http://amigo.geneontology.org/amigo/term/GO:0039530 |
| Similar Terms | |
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4 genes participating in the MDA-5 signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.
