MDAMB453 Gene Set

Dataset DepMap CRISPR Gene Dependency
Category disease or phenotype associations
Type cell line
External Link https://depmap.org/portal/cell_line/ACH-000910
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Genes

710 gene knockdowns changing fitness of MDAMB453 relative to other cell lines from the DepMap CRISPR Gene Dependency Dataset.

Symbol Name Standardized Value
CD300A CD300a molecule 14.9013
TFDP3 transcription factor Dp family, member 3 14.1735
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 13.8083
FGFR4 fibroblast growth factor receptor 4 12.7596
CEP112 centrosomal protein 112kDa 12.3297
PRR29 proline rich 29 12.3211
NOXA1 NADPH oxidase activator 1 11.9292
KIF19 kinesin family member 19 11.3586
GPC3 glypican 3 11.2625
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 11.2346
UBL4A ubiquitin-like 4A 11.0465
SLC51A solute carrier family 51, alpha subunit 10.9265
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 9.94057
MAGEA8 melanoma antigen family A8 9.50492
ZFP92 ZFP92 zinc finger protein 9.39211
TMEM86A transmembrane protein 86A 8.99837
BCL2L10 BCL2-like 10 (apoptosis facilitator) 8.9114
TRPS1 trichorhinophalangeal syndrome I 8.78695
SPANXB1 SPANX family, member B1 8.70011
OTOP2 otopetrin 2 8.68148
HELT helt bHLH transcription factor 8.56099
TCTEX1D2 Tctex1 domain containing 2 8.48786
SPDEF SAM pointed domain containing ETS transcription factor 8.45938
FADS6 fatty acid desaturase 6 8.43981
CDK18 cyclin-dependent kinase 18 8.36109
CCDC88C coiled-coil domain containing 88C 8.27395
KCTD2 potassium channel tetramerization domain containing 2 7.95326
GJC2 gap junction protein, gamma 2, 47kDa 7.94886
COQ8A coenzyme Q8A 7.79137
C8G complement component 8, gamma polypeptide 7.75274
NRARP NOTCH-regulated ankyrin repeat protein 7.64261
ZDHHC19 zinc finger, DHHC-type containing 19 7.39738
CRHR1 corticotropin releasing hormone receptor 1 7.20698
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 7.09417
GNG13 guanine nucleotide binding protein (G protein), gamma 13 7.02865
NT5C 5', 3'-nucleotidase, cytosolic 6.97755
ARRDC1 arrestin domain containing 1 6.95562
RAB37 RAB37, member RAS oncogene family 6.91448
CSHL1 chorionic somatomammotropin hormone-like 1 6.91021
TMEM210 transmembrane protein 210 6.89335
PKP3 plakophilin 3 6.82739
BEGAIN brain-enriched guanylate kinase-associated 6.63492
CLDN16 claudin 16 6.61083
RREB1 ras responsive element binding protein 1 6.57175
ATF3 activating transcription factor 3 6.55245
NR2F1 nuclear receptor subfamily 2, group F, member 1 6.53974
GPR142 G protein-coupled receptor 142 6.52297
CDHR5 cadherin-related family member 5 6.4802
SEC31A SEC31 homolog A (S. cerevisiae) 6.45115
NTPCR nucleoside-triphosphatase, cancer-related 6.41531
SLITRK3 SLIT and NTRK-like family, member 3 6.35578
KDM6A lysine (K)-specific demethylase 6A 6.33438
KIF26A kinesin family member 26A 6.29201
DLAT dihydrolipoamide S-acetyltransferase 6.12112
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 6.0931
NID1 nidogen 1 6.08953
PDHB pyruvate dehydrogenase (lipoamide) beta 5.97647
MTARC1 mitochondrial amidoxime reducing component 1 5.97378
SECISBP2L SECIS binding protein 2-like 5.92051
TOR4A torsin family 4, member A 5.89105
FBXL22 F-box and leucine-rich repeat protein 22 5.83164
PDHX pyruvate dehydrogenase complex, component X 5.82233
TMEM94 transmembrane protein 94 5.80033
AK7 adenylate kinase 7 5.64491
ANGEL1 angel homolog 1 (Drosophila) 5.62439
IGSF21 immunoglobin superfamily, member 21 5.58301
CD300LF CD300 molecule-like family member f 5.57962
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 5.55418
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1 5.54775
MAGEA11 melanoma antigen family A11 5.48635
TKTL1 transketolase-like 1 5.4725
TPM1 tropomyosin 1 (alpha) 5.47156
GPRC5C G protein-coupled receptor, class C, group 5, member C 5.46259
FAM71A family with sequence similarity 71, member A 5.43735
C1ORF35 chromosome 1 open reading frame 35 5.43008
PLEC plectin 5.40913
DPH7 diphthamide biosynthesis 7 5.38398
NFIA nuclear factor I/A 5.30628
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 5.28181
ZBTB7B zinc finger and BTB domain containing 7B 5.26396
LCN6 lipocalin 6 5.25757
IRX3 iroquois homeobox 3 5.20944
PPIB peptidylprolyl isomerase B (cyclophilin B) 5.15745
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 5.14879
MTFR1L mitochondrial fission regulator 1-like 5.13501
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 5.12873
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 5.12555
TMEM249 transmembrane protein 249 5.10211
OR2G6 olfactory receptor, family 2, subfamily G, member 6 5.08068
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) 5.05648
LY6H lymphocyte antigen 6 complex, locus H 5.03591
LCNL1 lipocalin-like 1 5.0097
ADGRB1 adhesion G protein-coupled receptor B1 4.99753
FAM132A family with sequence similarity 132, member A 4.9676
FBXW5 F-box and WD repeat domain containing 5 4.91038
TSNARE1 t-SNARE domain containing 1 4.85461
PLA2R1 phospholipase A2 receptor 1, 180kDa 4.81234
KMT2C lysine (K)-specific methyltransferase 2C 4.79355
SNX22 sorting nexin 22 4.77991
GOLIM4 golgi integral membrane protein 4 4.75345
FUCA1 fucosidase, alpha-L- 1, tissue 4.73575
CLCN2 chloride channel, voltage-sensitive 2 4.72989
MELTF melanotransferrin 4.72893
PACC1 proton activated chloride channel 1 4.72763
GPR68 G protein-coupled receptor 68 4.71535
RENBP renin binding protein 4.71469
ITGA11 integrin, alpha 11 4.71296
IRX5 iroquois homeobox 5 4.68861
BTBD17 BTB (POZ) domain containing 17 4.68855
TLN2 talin 2 4.67214
SURF1 surfeit 1 4.65135
S100A16 S100 calcium binding protein A16 4.63908
KLF7 Kruppel-like factor 7 (ubiquitous) 4.61765
ASXL1 additional sex combs like transcriptional regulator 1 4.60712
LCN8 lipocalin 8 4.5852
ODF3 outer dense fiber of sperm tails 3 4.56633
GATA3 GATA binding protein 3 4.50032
CCDC81 coiled-coil domain containing 81 4.49805
ATP13A4 ATPase type 13A4 4.49638
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 4.49358
EID1 EP300 interacting inhibitor of differentiation 1 4.47674
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 4.47479
FZD2 frizzled class receptor 2 4.4613
PCGF1 polycomb group ring finger 1 4.44185
KLHL30 kelch-like family member 30 4.38246
SIX2 SIX homeobox 2 4.37608
FOXA1 forkhead box A1 4.36769
C1RL complement component 1, r subcomponent-like 4.36551
IRF7 interferon regulatory factor 7 4.34926
LYPD2 LY6/PLAUR domain containing 2 4.34685
CTAG2 cancer/testis antigen 2 4.34498
PRR35 proline rich 35 4.34125
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 4.34005
PNCK pregnancy up-regulated nonubiquitous CaM kinase 4.32019
MIF4GD MIF4G domain containing 4.29352
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 4.28466
TMEM104 transmembrane protein 104 4.264
STRADA STE20-related kinase adaptor alpha 4.25615
PRSS38 protease, serine, 38 4.25034
MFSD4 major facilitator superfamily domain containing 4 4.24297
SETMAR SET domain and mariner transposase fusion gene 4.23465
DPP7 dipeptidyl-peptidase 7 4.21295
C4ORF46 chromosome 4 open reading frame 46 4.2076
CCDC117 coiled-coil domain containing 117 4.15567
MAP3K3 mitogen-activated protein kinase kinase kinase 3 4.14779
TMEM276 transmembrane protein 276 4.14759
ASIC4 acid sensing (proton gated) ion channel family member 4 4.12645
TNK2 tyrosine kinase, non-receptor, 2 4.12517
ZAR1 zygote arrest 1 4.11298
MB21D2 Mab-21 domain containing 2 4.10784
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 4.08922
CRYGB crystallin, gamma B 4.07407
SDK2 sidekick cell adhesion molecule 2 4.05612
HID1 HID1 domain containing 4.04936
TMEM141 transmembrane protein 141 4.04836
C5ORF47 chromosome 5 open reading frame 47 4.04354
ASPG asparaginase 4.03729
PHPT1 phosphohistidine phosphatase 1 4.02993
TMEM198 transmembrane protein 198 4.01814
LIMD2 LIM domain containing 2 4.0016
DLEU7 deleted in lymphocytic leukemia, 7 3.98974
OR2M5 olfactory receptor, family 2, subfamily M, member 5 3.97976
OBSL1 obscurin-like 1 3.97445
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 3.97277
OR52D1 olfactory receptor, family 52, subfamily D, member 1 3.96373
RBM47 RNA binding motif protein 47 3.96174
GRHL3 grainyhead-like 3 (Drosophila) 3.95663
CLIC3 chloride intracellular channel 3 3.95068
CASZ1 castor zinc finger 1 3.94099
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 3.93404
ZDHHC5 zinc finger, DHHC-type containing 5 3.86259
SLC35D3 solute carrier family 35, member D3 3.85504
ACBD3 acyl-CoA binding domain containing 3 3.82996
WIPI1 WD repeat domain, phosphoinositide interacting 1 3.82058
NAT9 N-acetyltransferase 9 (GCN5-related, putative) 3.81863
CCDC184 coiled-coil domain containing 184 3.81014
SLC4A3 solute carrier family 4 (anion exchanger), member 3 3.80745
C2CD4C C2 calcium-dependent domain containing 4C 3.80463
RING1 ring finger protein 1 3.80181
PLEKHN1 pleckstrin homology domain containing, family N member 1 3.80013
RTP1 receptor (chemosensory) transporter protein 1 3.78136
HADH hydroxyacyl-CoA dehydrogenase 3.77198
UBXN11 UBX domain protein 11 3.76946
ARHGAP4 Rho GTPase activating protein 4 3.76186
KBTBD13 kelch repeat and BTB (POZ) domain containing 13 3.75993
GOLGA7 golgin A7 3.7539
C8ORF37 chromosome 8 open reading frame 37 3.75151
RRAD Ras-related associated with diabetes 3.74044
CHPF chondroitin polymerizing factor 3.73303
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 3.70255
ITFG1 integrin alpha FG-GAP repeat containing 1 3.69835
PPP4R4 protein phosphatase 4, regulatory subunit 4 3.69014
GBX1 gastrulation brain homeobox 1 3.68859
D2HGDH D-2-hydroxyglutarate dehydrogenase 3.68713
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 3.68658
MOSPD1 motile sperm domain containing 1 3.68528
KCTD3 potassium channel tetramerization domain containing 3 3.68093
ERBB3 erb-b2 receptor tyrosine kinase 3 3.65477
KLHDC7A kelch domain containing 7A 3.65331
KCTD15 potassium channel tetramerization domain containing 15 3.62797
CLCN7 chloride channel, voltage-sensitive 7 3.62418
C16ORF91 chromosome 16 open reading frame 91 3.60945
RAB39B RAB39B, member RAS oncogene family 3.59759
GRHL2 grainyhead-like 2 (Drosophila) 3.58313
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 3.57352
MRGPRX3 MAS-related GPR, member X3 3.56626
TMED8 transmembrane emp24 protein transport domain containing 8 3.55945
ATXN3 ataxin 3 3.55698
JMJD8 jumonji domain containing 8 3.55108
LCN15 lipocalin 15 3.54841
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 3.54275
MMP11 matrix metallopeptidase 11 3.53116
FOXH1 forkhead box H1 3.5266
TAS1R2 taste receptor, type 1, member 2 3.52256
DGKD diacylglycerol kinase, delta 130kDa 3.51822
L1CAM L1 cell adhesion molecule 3.51352
DGKZ diacylglycerol kinase, zeta 3.50465
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 3.49888
WDR53 WD repeat domain 53 3.49802
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 3.49521
PITPNM2 phosphatidylinositol transfer protein, membrane-associated 2 3.48321
CASP7 caspase 7, apoptosis-related cysteine peptidase 3.46597
GIPC3 GIPC PDZ domain containing family, member 3 3.46331
PATE3 prostate and testis expressed 3 3.45893
ARL8A ADP-ribosylation factor-like 8A 3.45857
RNF224 ring finger protein 224 3.45663
TPRG1L tumor protein p63 regulated 1-like 3.43581
HTRA1 HtrA serine peptidase 1 3.42612
GATD1 glutamine amidotransferase class 1 domain containing 1 3.42501
CD248 CD248 molecule, endosialin 3.42102
ADCY8 adenylate cyclase 8 (brain) 3.42002
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 3.41496
SYNDIG1 synapse differentiation inducing 1 3.37685
NENF neudesin neurotrophic factor 3.37148
CCDC183 coiled-coil domain containing 183 3.37015
IDS iduronate 2-sulfatase 3.35367
TLR5 toll-like receptor 5 3.34991
LCN10 lipocalin 10 3.34891
TMEM121 transmembrane protein 121 3.3206
HIST3H2BB histone cluster 3, H2bb 3.31415
NOS3 nitric oxide synthase 3 (endothelial cell) 3.30263
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 3.3019
LECT1 leukocyte cell derived chemotaxin 1 3.29231
SLC39A14 solute carrier family 39 (zinc transporter), member 14 3.29223
SECTM1 secreted and transmembrane 1 3.29213
SSH2 slingshot protein phosphatase 2 3.27918
VWA2 von Willebrand factor A domain containing 2 3.2791
CEP19 centrosomal protein 19kDa 3.27076
ACTN2 actinin, alpha 2 3.26586
ISM2 isthmin 2 3.26509
TRIM17 tripartite motif containing 17 3.26438
RAB35 RAB35, member RAS oncogene family 3.26355
GPR35 G protein-coupled receptor 35 3.26038
KCNU1 potassium channel, subfamily U, member 1 3.24498
BRI3BP BRI3 binding protein 3.23958
MUC4 mucin 4, cell surface associated 3.23777
ARHGEF19 Rho guanine nucleotide exchange factor (GEF) 19 3.23653
CCDC166 coiled-coil domain containing 166 3.23172
SMIM9 small integral membrane protein 9 3.22698
MKNK1 MAP kinase interacting serine/threonine kinase 1 3.21532
JPT1 Jupiter microtubule associated homolog 1 3.21385
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 3.21139
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 3.20702
TSPAN17 tetraspanin 17 3.20656
C14ORF79 chromosome 14 open reading frame 79 3.20542
GFPT2 glutamine-fructose-6-phosphate transaminase 2 3.20365
SCO1 SCO1 cytochrome c oxidase assembly protein 3.20303
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 3.20125
KDM7A lysine (K)-specific demethylase 7A 3.19536
TFAP2D transcription factor AP-2 delta (activating enhancer binding protein 2 delta) 3.19277
CPN2 carboxypeptidase N, polypeptide 2 3.18396
DSTYK dual serine/threonine and tyrosine protein kinase 3.16824
PHACTR2 phosphatase and actin regulator 2 3.16518
RNPEP arginyl aminopeptidase (aminopeptidase B) 3.15845
ZNF652 zinc finger protein 652 3.15824
GSDMB gasdermin B 3.15415
ELL3 elongation factor RNA polymerase II-like 3 3.14785
PCNXL2 pecanex-like 2 (Drosophila) 3.1474
CHPF2 chondroitin polymerizing factor 2 3.14519
RAX2 retina and anterior neural fold homeobox 2 3.13756
CDK13 cyclin-dependent kinase 13 3.13286
TNNI1 troponin I type 1 (skeletal, slow) 3.13055
CORO1B coronin, actin binding protein, 1B 3.12851
APOPT1 apoptogenic 1, mitochondrial 3.12677
ZBED4 zinc finger, BED-type containing 4 3.12623
PPAPDC1A phosphatidic acid phosphatase type 2 domain containing 1A 3.10973
FBXO2 F-box protein 2 3.10669
GHSR growth hormone secretagogue receptor 3.10289
SHC4 SHC (Src homology 2 domain containing) family, member 4 3.09951
ACSBG2 acyl-CoA synthetase bubblegum family member 2 3.09492
SLC45A2 solute carrier family 45, member 2 3.09267
TCAF1 TRPM8 channel-associated factor 1 3.09214
TMEM87A transmembrane protein 87A 3.08948
DIAPH1 diaphanous-related formin 1 3.08726
MYEOV myeloma overexpressed 3.08015
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 3.0783
CAV3 caveolin 3 3.07795
OXER1 oxoeicosanoid (OXE) receptor 1 3.07529
MUC20 mucin 20, cell surface associated 3.07327
IREB2 iron-responsive element binding protein 2 3.06724
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 3.06411
C11ORF94 chromosome 11 open reading frame 94 3.06313
CALY calcyon neuron-specific vesicular protein 3.06079
SDHAF1 succinate dehydrogenase complex assembly factor 1 3.05954
TEX22 testis expressed 22 3.05626
RTN4IP1 reticulon 4 interacting protein 1 3.05111
RNF126 ring finger protein 126 3.04052
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 3.03985
EDN2 endothelin 2 3.03432
AVPR2 arginine vasopressin receptor 2 3.03254
KIAA2013 KIAA2013 3.0302
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 3.03
CD52 CD52 molecule 3.02604
PPARD peroxisome proliferator-activated receptor delta 3.01928
RAB40C RAB40C, member RAS oncogene family 3.01602
GSTCD glutathione S-transferase, C-terminal domain containing 3.01466
LIPT1 lipoyltransferase 1 3.0087
SLC38A10 solute carrier family 38, member 10 3.00133
GLTP glycolipid transfer protein 2.99945
SPTBN5 spectrin, beta, non-erythrocytic 5 2.99936
LAT linker for activation of T cells 2.99818
EIF4E1B eukaryotic translation initiation factor 4E family member 1B 2.99408
TRPM5 transient receptor potential cation channel, subfamily M, member 5 2.98088
QRICH2 glutamine rich 2 2.96939
SPPL2C signal peptide peptidase like 2C 2.9687
OR2A5 olfactory receptor, family 2, subfamily A, member 5 2.96575
MFAP3 microfibrillar-associated protein 3 2.96206
SHBG sex hormone-binding globulin 2.95799
IGFL2 IGF-like family member 2 2.95077
JPT2 Jupiter microtubule associated homolog 2 2.94868
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 2.94477
GFUS GDP-L-fucose synthase 2.94416
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B 2.9327
MIEN1 migration and invasion enhancer 1 2.93006
PNMA6A paraneoplastic Ma antigen family member 6A 2.928
NEU2 sialidase 2 (cytosolic sialidase) 2.92624
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 2.9221
RNASEH1 ribonuclease H1 2.92011
OMP olfactory marker protein 2.91705
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 2.91249
SCHIP1 schwannomin interacting protein 1 2.9052
S1PR4 sphingosine-1-phosphate receptor 4 2.89307
ACAD9 acyl-CoA dehydrogenase family, member 9 2.89124
MTERF4 mitochondrial transcription termination factor 4 2.88776
NKX1-2 NK1 homeobox 2 2.88301
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 2.88186
TEX2 testis expressed 2 2.87565
PIGX phosphatidylinositol glycan anchor biosynthesis, class X 2.87486
DIRAS1 DIRAS family, GTP-binding RAS-like 1 2.86777
CR1L complement component (3b/4b) receptor 1-like 2.86558
NUAK2 NUAK family, SNF1-like kinase, 2 2.8623
PET117 PET117 homolog (S. cerevisiae) 2.8507
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 2.85003
LRRC15 leucine rich repeat containing 15 2.84536
KDM4B lysine (K)-specific demethylase 4B 2.84519
CCDC9B coiled-coil domain containing 9B 2.84306
LMNTD2 lamin tail domain containing 2 2.84268
RTP2 receptor (chemosensory) transporter protein 2 2.83213
SLITRK4 SLIT and NTRK-like family, member 4 2.8281
LRRC47 leucine rich repeat containing 47 2.82424
CHRND cholinergic receptor, nicotinic, delta (muscle) 2.81644
DISP2 dispatched homolog 2 (Drosophila) 2.81175
CDYL chromodomain protein, Y-like 2.81129
TTLL4 tubulin tyrosine ligase-like family member 4 2.80841
VN1R2 vomeronasal 1 receptor 2 2.80819
SIMC1 SUMO-interacting motifs containing 1 2.80355
ANKRD33 ankyrin repeat domain 33 2.79894
C17ORF99 chromosome 17 open reading frame 99 2.79796
SLC35F3 solute carrier family 35, member F3 2.7835
ITPKA inositol-trisphosphate 3-kinase A 2.77857
CCSAP centriole, cilia and spindle-associated protein 2.7775
HGH1 HGH1 homolog (S. cerevisiae) 2.76253
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.76239
CD79B CD79b molecule, immunoglobulin-associated beta 2.75396
LCN12 lipocalin 12 2.75351
FBLN5 fibulin 5 2.75307
ADRA2A adrenoceptor alpha 2A 2.74887
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 2.74403
SLURP2 secreted LY6/PLAUR domain containing 2 2.74323
RNF223 ring finger protein 223 2.74181
FAM214B family with sequence similarity 214, member B 2.73917
PRPS1 phosphoribosyl pyrophosphate synthetase 1 2.73011
CAPN9 calpain 9 2.72868
GPR135 G protein-coupled receptor 135 2.72504
ALAD aminolevulinate dehydratase 2.7219
SERP2 stress-associated endoplasmic reticulum protein family member 2 2.71825
HPRT1 hypoxanthine phosphoribosyltransferase 1 2.71784
HSPG2 heparan sulfate proteoglycan 2 2.71759
EPS8L2 EPS8-like 2 2.71302
WDR20 WD repeat domain 20 2.71086
NEUROD2 neuronal differentiation 2 2.70527
GJD4 gap junction protein, delta 4, 40.1kDa 2.70295
ZNF7 zinc finger protein 7 2.69515
LRRC24 leucine rich repeat containing 24 2.69089
MPP1 membrane protein, palmitoylated 1, 55kDa 2.69016
PLCB2 phospholipase C, beta 2 2.6862
CD5 CD5 molecule 2.68457
RPUSD3 RNA pseudouridylate synthase domain containing 3 2.68132
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 2.67902
DOK3 docking protein 3 2.67594
BTBD2 BTB (POZ) domain containing 2 2.67332
ERBB2 erb-b2 receptor tyrosine kinase 2 2.67153
HABP4 hyaluronan binding protein 4 2.66869
FUT2 fucosyltransferase 2 (secretor status included) 2.66754
FAM43A family with sequence similarity 43, member A 2.66097
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 2.66045
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 2.65823
RGS19 regulator of G-protein signaling 19 2.65584
PLD4 phospholipase D family, member 4 2.65328
KLHDC8A kelch domain containing 8A 2.65316
RYR2 ryanodine receptor 2 (cardiac) 2.65134
EMP2 epithelial membrane protein 2 2.64909
CA7 carbonic anhydrase VII 2.64687
SCARB1 scavenger receptor class B, member 1 2.64523
OR2T29 olfactory receptor, family 2, subfamily T, member 29 2.63885
CEP170B centrosomal protein 170B 2.63836
CHRDL2 chordin-like 2 2.63455
ASB13 ankyrin repeat and SOCS box containing 13 2.63177
HDDC2 HD domain containing 2 2.62661
FNDC1 fibronectin type III domain containing 1 2.62057
HPS5 Hermansky-Pudlak syndrome 5 2.61688
PLA2G4D phospholipase A2, group IVD (cytosolic) 2.61411
C9ORF24 chromosome 9 open reading frame 24 2.611
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 2.60995
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 2.60741
MAP1A microtubule-associated protein 1A 2.60735
ZNF689 zinc finger protein 689 2.60687
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 2.60635
SVIL supervillin 2.60469
PTAR1 protein prenyltransferase alpha subunit repeat containing 1 2.60455
HES3 hes family bHLH transcription factor 3 2.60157
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A 2.60073
IFITM1 interferon induced transmembrane protein 1 2.60052
PDGFC platelet derived growth factor C 2.59999
TAAR5 trace amine associated receptor 5 2.59576
MARCKS myristoylated alanine-rich protein kinase C substrate 2.59541
MPC2 mitochondrial pyruvate carrier 2 2.59167
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 2.5907
TNP1 transition protein 1 (during histone to protamine replacement) 2.59059
PARP10 poly (ADP-ribose) polymerase family, member 10 2.58906
FAS Fas cell surface death receptor 2.58885
CLDN11 claudin 11 2.58732
MTL5 metallothionein-like 5, testis-specific (tesmin) 2.58655
KIFBP kinesin family binding protein 2.58622
KLLN killin, p53-regulated DNA replication inhibitor 2.58396
NLGN1 neuroligin 1 2.58389
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 2.58213
RILPL2 Rab interacting lysosomal protein-like 2 2.57789
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 2.57695
ZDHHC22 zinc finger, DHHC-type containing 22 2.56869
FDX1 ferredoxin 1 2.56467
PCDH17 protocadherin 17 2.55828
CCNI2 cyclin I family, member 2 2.54737
UNC79 unc-79 homolog (C. elegans) 2.54471
GRSF1 G-rich RNA sequence binding factor 1 2.54469
ASB10 ankyrin repeat and SOCS box containing 10 2.54364
RBM33 RNA binding motif protein 33 2.5412
ZNF410 zinc finger protein 410 2.53638
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 2.53396
TIGD5 tigger transposable element derived 5 2.53323
SLC31A1 solute carrier family 31 (copper transporter), member 1 2.52532
NTSR1 neurotensin receptor 1 (high affinity) 2.52452
EXD3 exonuclease 3'-5' domain containing 3 2.52412
PDGFA platelet-derived growth factor alpha polypeptide 2.52275
CCRL2 chemokine (C-C motif) receptor-like 2 2.51728
HPCA hippocalcin 2.51561
PRLH prolactin releasing hormone 2.51437
PDIA2 protein disulfide isomerase family A, member 2 2.5138
FBXO28 F-box protein 28 2.50828
SEPHS1 selenophosphate synthetase 1 2.50824
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 2.49514
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 2.49477
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 2.48968
NBL1 neuroblastoma 1, DAN family BMP antagonist 2.48813
SKOR1 SKI family transcriptional corepressor 1 2.48076
CA9 carbonic anhydrase IX 2.47925
PGBD2 piggyBac transposable element derived 2 2.47908
PRSS37 protease, serine, 37 2.47565
CYLD cylindromatosis (turban tumor syndrome) 2.46988
LEMD2 LEM domain containing 2 2.46944
ZBED3 zinc finger, BED-type containing 3 2.46747
PIGH phosphatidylinositol glycan anchor biosynthesis, class H 2.46108
NLRX1 NLR family member X1 2.45964
LRRC3C leucine rich repeat containing 3C 2.45781
MALSU1 mitochondrial assembly of ribosomal large subunit 1 2.4552
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 2.45405
AVPR1B arginine vasopressin receptor 1B 2.45158
RAB8B RAB8B, member RAS oncogene family 2.44616
PUSL1 pseudouridylate synthase-like 1 2.43854
ZDHHC24 zinc finger, DHHC-type containing 24 2.43846
KEAP1 kelch-like ECH-associated protein 1 2.4333
VASH1 vasohibin 1 2.43321
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1 2.43069
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 2.42957
SAP30 Sin3A-associated protein, 30kDa 2.4249
REN renin 2.42401
ZNF784 zinc finger protein 784 2.42229
TMEM37 transmembrane protein 37 2.42172
FBXL16 F-box and leucine-rich repeat protein 16 2.41698
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) 2.41465
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.41033
CRAMP1 cramped chromatin regulator homolog 1 2.40929
GPRIN1 G protein regulated inducer of neurite outgrowth 1 2.40576
FAM166A family with sequence similarity 166, member A 2.40304
QRICH1 glutamine-rich 1 2.39964
RAB40B RAB40B, member RAS oncogene family 2.39875
TSPAN32 tetraspanin 32 2.39634
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 2.39018
PRKCA protein kinase C, alpha 2.38698
OR2A2 olfactory receptor, family 2, subfamily A, member 2 2.38292
NCR2 natural cytotoxicity triggering receptor 2 2.38005
DRAXIN dorsal inhibitory axon guidance protein 2.37659
RHPN1 rhophilin, Rho GTPase binding protein 1 2.37646
PDCD6 programmed cell death 6 2.37623
SLC22A23 solute carrier family 22, member 23 2.36705
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.36187
HEPACAM2 HEPACAM family member 2 2.3616
OR6V1 olfactory receptor, family 6, subfamily V, member 1 2.35751
DENND3 DENN/MADD domain containing 3 2.35083
OR6B1 olfactory receptor, family 6, subfamily B, member 1 2.3494
ADAMTSL2 ADAMTS-like 2 2.34922
PRR7 proline rich 7 (synaptic) 2.34897
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 2.34894
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 2.34378
B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4 2.33875
DVL3 dishevelled segment polarity protein 3 2.33847
SIPA1L2 signal-induced proliferation-associated 1 like 2 2.33547
XXYLT1 xyloside xylosyltransferase 1 2.33493
C8ORF82 chromosome 8 open reading frame 82 2.33269
RPS6KL1 ribosomal protein S6 kinase-like 1 2.33027
GH1 growth hormone 1 2.32097
SHCBP1 SHC SH2-domain binding protein 1 2.32096
PHF13 PHD finger protein 13 2.32094
UIMC1 ubiquitin interaction motif containing 1 2.31992
TREML1 triggering receptor expressed on myeloid cells-like 1 2.31855
AMDHD2 amidohydrolase domain containing 2 2.31809
UBE2O ubiquitin-conjugating enzyme E2O 2.31534
DPYSL4 dihydropyrimidinase-like 4 2.31393
MMRN2 multimerin 2 2.31222
TNC tenascin C 2.31067
RASD2 RASD family, member 2 2.30971
TJAP1 tight junction associated protein 1 (peripheral) 2.30595
JOSD1 Josephin domain containing 1 2.30466
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 2.30091
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 2.30069
PRDM16 PR domain containing 16 2.3005
ADORA1 adenosine A1 receptor 2.29809
SH3BP5L SH3-binding domain protein 5-like 2.29575
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 2.29414
CDC42SE1 CDC42 small effector 1 2.29279
THBS1 thrombospondin 1 2.28746
PLA2G2F phospholipase A2, group IIF 2.28664
LAMP1 lysosomal-associated membrane protein 1 2.28614
PNKD paroxysmal nonkinesigenic dyskinesia 2.28518
TMEM44 transmembrane protein 44 2.28193
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 2.28029
TP53I3 tumor protein p53 inducible protein 3 2.27989
GIMAP8 GTPase, IMAP family member 8 2.27923
XDH xanthine dehydrogenase 2.27909
SERINC4 serine incorporator 4 2.27764
SSR4 signal sequence receptor, delta 2.2772
B3GNT1 2.26918
SLC10A4 solute carrier family 10, member 4 2.26847
C7ORF34 chromosome 7 open reading frame 34 2.26747
RXFP2 relaxin/insulin-like family peptide receptor 2 2.2672
PIGY phosphatidylinositol glycan anchor biosynthesis, class Y 2.26449
OR10AD1 olfactory receptor, family 10, subfamily AD, member 1 2.26391
DIPK1B divergent protein kinase domain 1B 2.26258
APOLD1 apolipoprotein L domain containing 1 2.2616
DLD dihydrolipoamide dehydrogenase 2.26146
LAMP3 lysosomal-associated membrane protein 3 2.25925
MED13 mediator complex subunit 13 2.25724
CD300C CD300c molecule 2.2554
PHF21B PHD finger protein 21B 2.2541
SLC36A4 solute carrier family 36 (proton/amino acid symporter), member 4 2.25376
CHRM4 cholinergic receptor, muscarinic 4 2.25215
TTYH2 tweety family member 2 2.25152
STMN3 stathmin-like 3 2.25084
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 2.24945
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1 2.2459
OR2T2 olfactory receptor, family 2, subfamily T, member 2 2.24517
TULP2 tubby like protein 2 2.24461
CRYGC crystallin, gamma C 2.24348
RNF123 ring finger protein 123 2.24159
SDC1 syndecan 1 2.23577
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 2.23554
DVL1 dishevelled segment polarity protein 1 2.2289
RERE arginine-glutamic acid dipeptide (RE) repeats 2.22732
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 2.22526
GLIS2 GLIS family zinc finger 2 2.2221
CCDC51 coiled-coil domain containing 51 2.22137
PC pyruvate carboxylase 2.21963
LRIT1 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1 2.21829
C6ORF1 chromosome 6 open reading frame 1 2.21711
LAMA5 laminin, alpha 5 2.21328
C2CD4A C2 calcium-dependent domain containing 4A 2.20869
ACTA1 actin, alpha 1, skeletal muscle 2.20551
ESRP2 epithelial splicing regulatory protein 2 2.20383
FOXRED1 FAD-dependent oxidoreductase domain containing 1 2.19952
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) 2.19513
PCGF3 polycomb group ring finger 3 2.1943
PITRM1 pitrilysin metallopeptidase 1 2.1927
C1ORF86 chromosome 1 open reading frame 86 2.19097
FBXL6 F-box and leucine-rich repeat protein 6 2.18841
CALML4 calmodulin-like 4 2.18276
ANO2 anoctamin 2, calcium activated chloride channel 2.18226
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 2.18182
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 2.1812
MRPL51 mitochondrial ribosomal protein L51 2.18038
NKAIN4 Na+/K+ transporting ATPase interacting 4 2.17975
ZDBF2 zinc finger, DBF-type containing 2 2.176
MBD3 methyl-CpG binding domain protein 3 2.17193
EXOC3L4 exocyst complex component 3-like 4 2.17186
PCSK1 proprotein convertase subtilisin/kexin type 1 2.16961
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 2.16843
OGFR opioid growth factor receptor 2.16825
GALNT9 polypeptide N-acetylgalactosaminyltransferase 9 2.16771
COA6 cytochrome c oxidase assembly factor 6 2.15844
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 2.1565
C1ORF95 chromosome 1 open reading frame 95 2.15603
PLEKHS1 pleckstrin homology domain containing, family S member 1 2.15342
SLC39A4 solute carrier family 39 (zinc transporter), member 4 2.15281
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative) 2.15218
ETV7 ets variant 7 2.14912
ZFPM1 zinc finger protein, FOG family member 1 2.14779
TYRO3 TYRO3 protein tyrosine kinase 2.14741
DNAI2 dynein, axonemal, intermediate chain 2 2.14586
PARK7 parkinson protein 7 2.14545
DYNLT3 dynein, light chain, Tctex-type 3 2.14367
ANKDD1A ankyrin repeat and death domain containing 1A 2.14362
COMMD5 COMM domain containing 5 2.14201
MAMDC4 MAM domain containing 4 2.13824
NUDCD2 NudC domain containing 2 2.13749
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 2.1367
FAM47B family with sequence similarity 47, member B 2.13356
ATG16L2 autophagy related 16-like 2 (S. cerevisiae) 2.13174
CSH2 chorionic somatomammotropin hormone 2 2.131
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase 2.13083
WDSUB1 WD repeat, sterile alpha motif and U-box domain containing 1 2.12766
GATAD2B GATA zinc finger domain containing 2B 2.12699
KIAA1191 KIAA1191 2.12696
METTL25 methyltransferase like 25 2.1264
CACFD1 calcium channel flower domain containing 1 2.12638
CCDC92 coiled-coil domain containing 92 2.12169
ZFAND2B zinc finger, AN1-type domain 2B 2.12007
C20ORF195 chromosome 20 open reading frame 195 2.11984
IRGM immunity-related GTPase family, M 2.11547
PACS2 phosphofurin acidic cluster sorting protein 2 2.11181
HMBS hydroxymethylbilane synthase 2.10997
IFT80 intraflagellar transport 80 2.10877
RASGEF1C RasGEF domain family, member 1C 2.10785
PEF1 penta-EF-hand domain containing 1 2.10747
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 2.10664
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 2.10505
TMEM132D transmembrane protein 132D 2.1013
RASL12 RAS-like, family 12 2.09887
C1ORF159 chromosome 1 open reading frame 159 2.09619
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 2.09483
CD164 CD164 molecule, sialomucin 2.09213
PTPRN protein tyrosine phosphatase, receptor type, N 2.0917
TRAM1L1 translocation associated membrane protein 1-like 1 2.08805
OR51Q1 olfactory receptor, family 51, subfamily Q, member 1 (gene/pseudogene) 2.08783
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38 2.08768
GPATCH3 G patch domain containing 3 2.0873
TMEM52B transmembrane protein 52B 2.08582
ZNF696 zinc finger protein 696 2.08127
PLBD2 phospholipase B domain containing 2 2.07832
FAM110A family with sequence similarity 110, member A 2.07663
CSMD3 CUB and Sushi multiple domains 3 2.07649
C9ORF69 chromosome 9 open reading frame 69 2.07376
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 2.06633
USP50 ubiquitin specific peptidase 50 2.06595
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 2.06593
SH3PXD2B SH3 and PX domains 2B 2.06253
GRK5 G protein-coupled receptor kinase 5 2.0616
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 2.06101
C9ORF173 chromosome 9 open reading frame 173 2.05566
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 2.05335
CCR9 chemokine (C-C motif) receptor 9 2.05156
FAM131C family with sequence similarity 131, member C 2.05063
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 2.0489
CHKA choline kinase alpha 2.04862
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 2.04625
WBP1L WW domain binding protein 1-like 2.04561
ARRB1 arrestin, beta 1 2.04375
PLA2G4F phospholipase A2, group IVF 2.04225
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 2.03626
SFRP2 secreted frizzled-related protein 2 2.03468
TMEM81 transmembrane protein 81 2.03414
FANCD2OS FANCD2 opposite strand 2.03403
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) 2.02954
BOD1L1 biorientation of chromosomes in cell division 1-like 1 2.02744
HARS2 histidyl-tRNA synthetase 2, mitochondrial 2.02711
TREM2 triggering receptor expressed on myeloid cells 2 2.0229
MTRF1L mitochondrial translational release factor 1-like 2.0195
COX18 COX18 cytochrome c oxidase assembly factor 2.01913
PNMA5 paraneoplastic Ma antigen family member 5 2.0142
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 2.01197
MOG myelin oligodendrocyte glycoprotein 2.01162
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.00955
MFAP5 microfibrillar associated protein 5 2.00795
CHD5 chromodomain helicase DNA binding protein 5 2.00766
NUCB1 nucleobindin 1 2.00706
PDE10A phosphodiesterase 10A 2.00668
RAB29 RAB29, member RAS oncogene family 2.00598
DGAT1 diacylglycerol O-acyltransferase 1 2.0044
RBM34 RNA binding motif protein 34 2.00303
ZNF470 zinc finger protein 470 2.00249
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 2.00196
COX4I1 cytochrome c oxidase subunit IV isoform 1 2.00012