| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | mediator of DNA-damage checkpoint 1|The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9656) |
| External Link | https://ncbi.nlm.nih.gov/gene/9656 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the MDC1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | 0.0316258 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0112667 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0107291 |
| RGS5 | regulator of G-protein signaling 5 | 0.0106467 |
| CD320 | CD320 molecule | 0.0105594 |
| XPO7 | exportin 7 | 0.0104152 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00983786 |
| NPEPL1 | aminopeptidase-like 1 | 0.0093172 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | 0.0093115 |
| ARG2 | arginase 2 | 0.00902903 |
| SPRR3 | small proline-rich protein 3 | 0.0087406 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00866546 |
| CDCA4 | cell division cycle associated 4 | 0.00855637 |
| FTO | fat mass and obesity associated | 0.00844291 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00842839 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00811222 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00796726 |
| KRT13 | keratin 13, type I | 0.00792213 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00787208 |
| SIRT3 | sirtuin 3 | 0.00785267 |
| COPS7A | COP9 signalosome subunit 7A | 0.00773223 |
| S100A2 | S100 calcium binding protein A2 | 0.00772198 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0076073 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00759259 |
| PRDX2 | peroxiredoxin 2 | 0.00743572 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00740435 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00738994 |
| PLA2G12A | phospholipase A2, group XIIA | 0.00738823 |
| SORD | sorbitol dehydrogenase | 0.0073873 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.0073694 |
| GANAB | glucosidase, alpha; neutral AB | 0.0073245 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.00731239 |
| ACP3 | acid phosphatase 3 | 0.00730727 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00729803 |
| RNASEH2A | ribonuclease H2, subunit A | 0.00726905 |
| EIF4E | eukaryotic translation initiation factor 4E | 0.00715883 |
| BEX1 | brain expressed, X-linked 1 | 0.00712639 |
| KLHL23 | kelch-like family member 23 | 0.00712294 |
| NEFH | neurofilament, heavy polypeptide | 0.00708629 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.00707927 |
| L1TD1 | LINE-1 type transposase domain containing 1 | 0.00701831 |
| MATN2 | matrilin 2 | 0.00692119 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00691675 |
| NMU | neuromedin U | 0.00691014 |
| COL4A6 | collagen, type IV, alpha 6 | 0.00690471 |
| GSTT1 | glutathione S-transferase theta 1 | 0.00681321 |
| LTA4H | leukotriene A4 hydrolase | 0.00681263 |
| ZBED8 | zinc finger, BED-type containing 8 | 0.00675499 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00672718 |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) | 0.00672317 |
| SCG5 | secretogranin V | 0.00670353 |
| KRT6A | keratin 6A, type II | 0.00662558 |
| OLFM1 | olfactomedin 1 | 0.00662294 |
| SPRR1B | small proline-rich protein 1B | 0.00662197 |
| LIG1 | ligase I, DNA, ATP-dependent | 0.0066164 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | 0.00661636 |
| EMP2 | epithelial membrane protein 2 | 0.00661161 |
| GPC4 | glypican 4 | 0.00659501 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.00653714 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00652227 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.00650287 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.00650273 |
| PCGF2 | polycomb group ring finger 2 | 0.006495 |
| MAL | mal, T-cell differentiation protein | 0.00647241 |
| FAM13A | family with sequence similarity 13, member A | 0.00646754 |
| WDR7 | WD repeat domain 7 | 0.00644841 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 0.00644075 |
| PRKCD | protein kinase C, delta | 0.0064222 |
| HMGB1 | high mobility group box 1 | 0.00636128 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00634328 |
| KIF20A | kinesin family member 20A | 0.0063408 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00631755 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 0.00629692 |
| NTS | neurotensin | 0.00626145 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.00624819 |
| TSPAN13 | tetraspanin 13 | 0.0062401 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.00623325 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00622997 |
| MOCS2 | molybdenum cofactor synthesis 2 | 0.00622674 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00619679 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.00614945 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.00612487 |
| CPE | carboxypeptidase E | 0.00611759 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00608857 |
| PGF | placental growth factor | 0.00607254 |
| PGD | phosphogluconate dehydrogenase | 0.00604803 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00602586 |
| RET | ret proto-oncogene | 0.00598776 |
| H2AFV | H2A histone family, member V | 0.00597763 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00596413 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00596147 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.00590621 |
| PF4 | platelet factor 4 | 0.00590458 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00587947 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.00587366 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.005861 |
| SYBU | syntabulin (syntaxin-interacting) | 0.00584212 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00584181 |
| HMGN5 | high mobility group nucleosome binding domain 5 | 0.00579275 |
| RAD51C | RAD51 paralog C | 0.00578876 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.00578699 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.00577761 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.00576686 |
| KIF18A | kinesin family member 18A | 0.00576383 |
| CDC20 | cell division cycle 20 | 0.00573926 |
| PBK | PDZ binding kinase | 0.00573589 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.00571253 |
| FANCL | Fanconi anemia, complementation group L | 0.00570208 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00569655 |
| PER1 | period circadian clock 1 | 0.00569002 |
| RBMX | RNA binding motif protein, X-linked | 0.00568486 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00567795 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00567599 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.00566935 |
| TMEM255A | transmembrane protein 255A | 0.00566566 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00565521 |
| FBL | fibrillarin | 0.00564628 |
| PEX3 | peroxisomal biogenesis factor 3 | 0.00564568 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.00564496 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | 0.00561183 |
| FOXF1 | forkhead box F1 | 0.00560624 |
| ESR1 | estrogen receptor 1 | 0.005584 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.00557739 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | 0.00557492 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00557299 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00557172 |
| ALDOC | aldolase C, fructose-bisphosphate | 0.00556877 |
| SEPTIN10 | septin 10 | 0.0055512 |
| SALL2 | spalt-like transcription factor 2 | 0.00553607 |
| CRNN | cornulin | 0.00552013 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00551851 |
| FAM120A | family with sequence similarity 120A | 0.00551026 |
| WDR76 | WD repeat domain 76 | 0.00550022 |
| S100A7 | S100 calcium binding protein A7 | 0.00549739 |
| ITM2C | integral membrane protein 2C | 0.00548977 |
| HOXB6 | homeobox B6 | 0.00548153 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.00547293 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.00545639 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00542986 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.00542008 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00539273 |
| GOT2 | glutamic-oxaloacetic transaminase 2, mitochondrial | 0.00539079 |
| EXO1 | exonuclease 1 | 0.00538912 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.00538537 |
| RPS5 | ribosomal protein S5 | 0.00537126 |
| RNF167 | ring finger protein 167 | 0.00536275 |
| PLBD1 | phospholipase B domain containing 1 | 0.00536146 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | 0.00536035 |
| PCYOX1L | prenylcysteine oxidase 1 like | 0.00535611 |
| TEAD4 | TEA domain family member 4 | 0.00534468 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00533652 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.0053358 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00531571 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | 0.00531384 |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 | 0.00531064 |
| PER3 | period circadian clock 3 | 0.00529428 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.0052924 |
| TPM2 | tropomyosin 2 (beta) | 0.00528639 |
| SPRR1A | small proline-rich protein 1A | 0.00526114 |
| CCNF | cyclin F | 0.00525447 |
| TNS1 | tensin 1 | 0.00525006 |
| ADIRF | adipogenesis regulatory factor | 0.00524522 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.0052322 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00522171 |
| RPL29 | ribosomal protein L29 | 0.0052211 |
| B3GALNT1 | beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) | 0.00521641 |
| RHCG | Rh family, C glycoprotein | 0.00520968 |
| ERGIC3 | ERGIC and golgi 3 | 0.0052051 |
| RPL10 | ribosomal protein L10 | 0.0051979 |
| RUVBL1 | RuvB-like AAA ATPase 1 | 0.00519668 |
| DCTN4 | dynactin 4 (p62) | 0.00519591 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00519577 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) | 0.00518035 |
| RPA3 | replication protein A3, 14kDa | 0.00517859 |
| HOXB2 | homeobox B2 | 0.00514995 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00514185 |
| ADK | adenosine kinase | 0.00514055 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 0.00512759 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.00512623 |
| CD99 | CD99 molecule | 0.00512529 |
| EPHB2 | EPH receptor B2 | 0.00510637 |
| PHB2 | prohibitin 2 | 0.00509515 |
| MLF2 | myeloid leukemia factor 2 | 0.00508531 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00507673 |
| USP4 | ubiquitin specific peptidase 4 (proto-oncogene) | 0.00507485 |
| SRPRA | SRP receptor subunit alpha | 0.00506949 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.00506293 |
| TMEM131L | transmembrane 131 like | 0.00505992 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | 0.00505871 |
| LRRC17 | leucine rich repeat containing 17 | 0.00504527 |
| BMERB1 | bMERB domain containing 1 | 0.00503578 |
| REEP1 | receptor accessory protein 1 | 0.0050262 |
| PLVAP | plasmalemma vesicle associated protein | 0.00501926 |
| NDUFA7 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa | 0.00501248 |
| CDC25C | cell division cycle 25C | 0.0050052 |
| DNTT | DNA nucleotidylexotransferase | 0.00500026 |
| MAZ | MYC-associated zinc finger protein (purine-binding transcription factor) | 0.00500002 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.00499583 |
| LIPT1 | lipoyltransferase 1 | 0.00499469 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 0.00498205 |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type | 0.00498158 |
| KIF23 | kinesin family member 23 | 0.00497832 |
| AFF1 | AF4/FMR2 family, member 1 | 0.00497784 |
| THAP10 | THAP domain containing 10 | 0.00497657 |
| RAD51AP1 | RAD51 associated protein 1 | 0.00497536 |
| ARL3 | ADP-ribosylation factor-like 3 | 0.00496976 |
| AUTS2 | autism susceptibility candidate 2 | 0.00495764 |
| NCAPG | non-SMC condensin I complex, subunit G | 0.00495666 |
| LOC730101 | uncharacterized LOC730101 | 0.00495412 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | 0.00494612 |
| TOP1 | topoisomerase (DNA) I | 0.00494559 |
| TUSC3 | tumor suppressor candidate 3 | 0.00493727 |
| DENND2B | DENN domain containing 2B | 0.00492748 |
| SHOX2 | short stature homeobox 2 | 0.00491145 |
| TPI1 | triosephosphate isomerase 1 | 0.0049008 |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | 0.00489319 |
| TPX2 | TPX2, microtubule-associated | 0.00489148 |
| UNC119B | unc-119 homolog B (C. elegans) | 0.00488757 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.00487904 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00487867 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.00487474 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.00486684 |
| SOX15 | SRY (sex determining region Y)-box 15 | 0.0048658 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.00486342 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.00486332 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00485632 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) | 0.00485363 |
| FBXO5 | F-box protein 5 | 0.00485327 |
| DCK | deoxycytidine kinase | 0.00485317 |
| CSF3R | colony stimulating factor 3 receptor (granulocyte) | 0.00485239 |
| ACTL6A | actin-like 6A | 0.00484413 |
| HCRT | hypocretin (orexin) neuropeptide precursor | 0.00483224 |
| PITX1 | paired-like homeodomain 1 | 0.00482798 |
| SORBS3 | sorbin and SH3 domain containing 3 | 0.00482618 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00481438 |
| ESD | esterase D | 0.00480024 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.00479936 |
| HDAC3 | histone deacetylase 3 | 0.00479812 |
| IVL | involucrin | 0.00479116 |
| BMP4 | bone morphogenetic protein 4 | 0.00478194 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.00477814 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | 0.00477267 |
| E2F8 | E2F transcription factor 8 | 0.00475909 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00474217 |
| AASS | aminoadipate-semialdehyde synthase | 0.00474137 |
| MSX1 | msh homeobox 1 | 0.00474012 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | 0.00473725 |
| SFTPB | surfactant protein B | 0.00473312 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.0047331 |
| SLC25A12 | solute carrier family 25 (aspartate/glutamate carrier), member 12 | 0.00472882 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0154283 |
| KRT23 | keratin 23, type I | -0.0136174 |
| THBS1 | thrombospondin 1 | -0.0133346 |
| NRCAM | neuronal cell adhesion molecule | -0.0130872 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.0126328 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.0120604 |
| CLEC2B | C-type lectin domain family 2, member B | -0.0114713 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.0113356 |
| CTSD | cathepsin D | -0.0111117 |
| THBS2 | thrombospondin 2 | -0.0109742 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0107536 |
| GPX2 | glutathione peroxidase 2 | -0.0106888 |
| HTRA1 | HtrA serine peptidase 1 | -0.0106255 |
| C3 | complement component 3 | -0.0105076 |
| KRT7 | keratin 7, type II | -0.0105003 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0104586 |
| TPD52L1 | tumor protein D52-like 1 | -0.0104002 |
| RRAGA | Ras-related GTP binding A | -0.0101864 |
| NNMT | nicotinamide N-methyltransferase | -0.0101404 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.0100674 |
| EVI2A | ecotropic viral integration site 2A | -0.00994062 |
| DSP | desmoplakin | -0.00993775 |
| CEL | carboxyl ester lipase | -0.00991032 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00987749 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00986094 |
| PMP22 | peripheral myelin protein 22 | -0.00980579 |
| COMP | cartilage oligomeric matrix protein | -0.00970085 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00969997 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00969742 |
| TLR4 | toll-like receptor 4 | -0.00963929 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.00951542 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00947899 |
| MXRA5 | matrix-remodelling associated 5 | -0.00939576 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00923437 |
| EGR3 | early growth response 3 | -0.00912877 |
| TOB1 | transducer of ERBB2, 1 | -0.00893177 |
| LIF | leukemia inhibitory factor | -0.00887426 |
| TAGLN | transgelin | -0.00884466 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.0087889 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.00872626 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00869418 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00867835 |
| HMOX1 | heme oxygenase 1 | -0.00864116 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00863021 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00861017 |
| BICC1 | BicC family RNA binding protein 1 | -0.00854915 |
| IER5 | immediate early response 5 | -0.00853278 |
| PROM1 | prominin 1 | -0.00850526 |
| AREG | amphiregulin | -0.00848404 |
| EMP1 | epithelial membrane protein 1 | -0.00833904 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00832394 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00828132 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00827763 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00827315 |
| APOD | apolipoprotein D | -0.00827036 |
| SNAI2 | snail family zinc finger 2 | -0.00814918 |
| PLPP2 | phospholipid phosphatase 2 | -0.008138 |
| IL1R1 | interleukin 1 receptor, type I | -0.00813466 |
| FBN1 | fibrillin 1 | -0.00803659 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | -0.00799948 |
| TUFT1 | tuftelin 1 | -0.00797803 |
| GPR137B | G protein-coupled receptor 137B | -0.0079688 |
| C3AR1 | complement component 3a receptor 1 | -0.0079614 |
| MFAP5 | microfibrillar associated protein 5 | -0.00793464 |
| CD163 | CD163 molecule | -0.007916 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00789866 |
| ATF3 | activating transcription factor 3 | -0.00787471 |
| PERP | PERP, TP53 apoptosis effector | -0.00784677 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00779916 |
| EREG | epiregulin | -0.00777479 |
| LTF | lactotransferrin | -0.0077177 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00771523 |
| PLIN2 | perilipin 2 | -0.0077134 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.00768953 |
| DCN | decorin | -0.00767368 |
| INHBA | inhibin, beta A | -0.00763246 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00763123 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00762417 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -0.00757853 |
| CADM1 | cell adhesion molecule 1 | -0.00757585 |
| MYRF | myelin regulatory factor | -0.00756528 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00755527 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.00752461 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00747258 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00739448 |
| NLRP2 | NLR family, pyrin domain containing 2 | -0.00739262 |
| TYMS | thymidylate synthetase | -0.00738609 |
| LXN | latexin | -0.00738519 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00737906 |
| IL6 | interleukin 6 | -0.00736548 |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs | -0.00736049 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.00720633 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00716533 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00715399 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00712564 |
| EPS8L2 | EPS8-like 2 | -0.00712093 |
| JAG1 | jagged 1 | -0.00705555 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00703289 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.00701919 |
| CYTH1 | cytohesin 1 | -0.00699006 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00696464 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00696309 |
| FGF9 | fibroblast growth factor 9 | -0.00695061 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00694727 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00690769 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | -0.006897 |
| KRT19 | keratin 19, type I | -0.00685345 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00684614 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.00684019 |
| POSTN | periostin, osteoblast specific factor | -0.00677257 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00676429 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.00675744 |
| TMEM70 | transmembrane protein 70 | -0.00674725 |
| TSPYL5 | TSPY-like 5 | -0.00674124 |
| PTK2B | protein tyrosine kinase 2 beta | -0.00673842 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00673602 |
| EGR2 | early growth response 2 | -0.00672404 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00669065 |
| ASRGL1 | asparaginase like 1 | -0.00667761 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.00665696 |
| TESC | tescalcin | -0.00665064 |
| PEG3 | paternally expressed 3 | -0.00663653 |
| CLEC3B | C-type lectin domain family 3, member B | -0.00661408 |
| RGS4 | regulator of G-protein signaling 4 | -0.00661008 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.0065982 |
| DUSP1 | dual specificity phosphatase 1 | -0.00659776 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00659483 |
| FGA | fibrinogen alpha chain | -0.00658309 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00658258 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00654802 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00653913 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00652874 |
| CLIC5 | chloride intracellular channel 5 | -0.00652299 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00651634 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00651494 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.0065102 |
| TSPO | translocator protein (18kDa) | -0.00650172 |
| MVP | major vault protein | -0.00650058 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00646868 |
| RNASET2 | ribonuclease T2 | -0.00644092 |
| GGT1 | gamma-glutamyltransferase 1 | -0.00643796 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00641027 |
| RHOF | ras homolog family member F (in filopodia) | -0.00640291 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | -0.00639437 |
| RAB29 | RAB29, member RAS oncogene family | -0.00639224 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00637874 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00636734 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00636096 |
| GUCY2C | guanylate cyclase 2C | -0.00634511 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.00633511 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | -0.00632068 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00631937 |
| SULF1 | sulfatase 1 | -0.00630818 |
| BAD | BCL2-associated agonist of cell death | -0.00630796 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | -0.00628287 |
| MMP7 | matrix metallopeptidase 7 | -0.00626169 |
| CRYAB | crystallin, alpha B | -0.00624681 |
| ASPN | asporin | -0.00623478 |
| CCNA2 | cyclin A2 | -0.00622739 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | -0.00621922 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.00621448 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00621273 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00620568 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.00619214 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00618986 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.00618132 |
| PYCARD | PYD and CARD domain containing | -0.00618132 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | -0.00614863 |
| COBL | cordon-bleu WH2 repeat protein | -0.00613732 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00610967 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.0061079 |
| NPAS2 | neuronal PAS domain protein 2 | -0.00608275 |
| CST1 | cystatin SN | -0.00607671 |
| TXLNA | taxilin alpha | -0.00606061 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00605888 |
| RETSAT | retinol saturase (all-trans-retinol 13,14-reductase) | -0.00604922 |
| STC2 | stanniocalcin 2 | -0.00604858 |
| LCN2 | lipocalin 2 | -0.0060475 |
| TMEM260 | transmembrane protein 260 | -0.00603666 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | -0.00603478 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00603448 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -0.00603133 |
| GRAMD2B | GRAM domain containing 2B | -0.00601259 |
| SLN | sarcolipin | -0.0060067 |
| ABHD6 | abhydrolase domain containing 6 | -0.00600416 |
| DUSP5 | dual specificity phosphatase 5 | -0.00597983 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.00597425 |
| PRAME | preferentially expressed antigen in melanoma | -0.00592617 |
| HEPH | hephaestin | -0.00592438 |
| CCNA1 | cyclin A1 | -0.00592397 |
| KRT8 | keratin 8, type II | -0.00588625 |
| FAM171A1 | family with sequence similarity 171, member A1 | -0.00587346 |
| NELL1 | NEL-like 1 (chicken) | -0.0058694 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00586275 |
| TRAPPC6A | trafficking protein particle complex 6A | -0.00585485 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.00583074 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00581054 |
| TULP4 | tubby like protein 4 | -0.00579168 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.00579156 |
| KLK5 | kallikrein-related peptidase 5 | -0.00579115 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | -0.00577191 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0057705 |
| BCL2A1 | BCL2-related protein A1 | -0.00576939 |
| CFD | complement factor D (adipsin) | -0.00573577 |
| FOLR1 | folate receptor 1 (adult) | -0.00572985 |
| PLK2 | polo-like kinase 2 | -0.00571934 |
| KRT81 | keratin 81, type II | -0.00571579 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.00570787 |
| MAMLD1 | mastermind-like domain containing 1 | -0.0057048 |
| GSN | gelsolin | -0.00569605 |
| CCN2 | cellular communication network factor 2 | -0.00568231 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00566745 |
| CFH | complement factor H | -0.00564531 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -0.00564447 |
| CLDN8 | claudin 8 | -0.00564396 |
| HPGDS | hematopoietic prostaglandin D synthase | -0.00563479 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | -0.00562036 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00561835 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.00561211 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.00560974 |
| ASS1 | argininosuccinate synthase 1 | -0.00560275 |
| LRRC8D | leucine rich repeat containing 8 family, member D | -0.00559925 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.00558901 |
| TPSAB1 | tryptase alpha/beta 1 | -0.0055779 |
| KIF13B | kinesin family member 13B | -0.00556245 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | -0.00555509 |
| PLIN1 | perilipin 1 | -0.00555496 |
| FHL2 | four and a half LIM domains 2 | -0.00554243 |
| PRSS23 | protease, serine, 23 | -0.00553558 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.0055196 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00550784 |
| LRRC15 | leucine rich repeat containing 15 | -0.00550601 |
| KLF2 | Kruppel-like factor 2 | -0.00548247 |
| ZNF264 | zinc finger protein 264 | -0.00547671 |
| KLF10 | Kruppel-like factor 10 | -0.00547162 |
| HGD | homogentisate 1,2-dioxygenase | -0.00546489 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00546155 |
| EFNB2 | ephrin-B2 | -0.00545823 |
| FGB | fibrinogen beta chain | -0.00544046 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | -0.00543035 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | -0.00542782 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00541973 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00541332 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00540745 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00540349 |
| SLC22A18 | solute carrier family 22, member 18 | -0.00539504 |
| DUSP4 | dual specificity phosphatase 4 | -0.00539202 |
| VCAN | versican | -0.00537275 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00536753 |
