| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | MDM2 proto-oncogene, E3 ubiquitin protein ligase|This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013] (NCBI Entrez Gene Database, 4193) |
| External Link | https://ncbi.nlm.nih.gov/gene/4193 |
| Similar Terms | |
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496 genes differentially expressed following the MDM2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0172882 |
| KRT14 | keratin 14, type I | 0.0137623 |
| KRT6A | keratin 6A, type II | 0.0126467 |
| SPRR1B | small proline-rich protein 1B | 0.0120379 |
| S100A2 | S100 calcium binding protein A2 | 0.011779 |
| KRT6B | keratin 6B, type II | 0.011431 |
| C1QA | complement component 1, q subcomponent, A chain | 0.0113783 |
| TRIM29 | tripartite motif containing 29 | 0.0112135 |
| KRT16 | keratin 16, type I | 0.0110442 |
| CNTN1 | contactin 1 | 0.0107168 |
| SFN | stratifin | 0.0105758 |
| ABLIM1 | actin binding LIM protein 1 | 0.010425 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.0103109 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.0102351 |
| ANXA3 | annexin A3 | 0.0102318 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 0.0101668 |
| ITGA6 | integrin, alpha 6 | 0.0100048 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00993254 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00978118 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 0.00958513 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00952003 |
| ZNF91 | zinc finger protein 91 | 0.00949202 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00942611 |
| FBN2 | fibrillin 2 | 0.00933737 |
| KRT17 | keratin 17, type I | 0.00931204 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00912945 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.00905196 |
| KRT5 | keratin 5, type II | 0.00898158 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00879974 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00859539 |
| BMP2 | bone morphogenetic protein 2 | 0.00858101 |
| SPRR1A | small proline-rich protein 1A | 0.00855246 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00852607 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0084347 |
| EFNB2 | ephrin-B2 | 0.00841735 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.00832442 |
| PERP | PERP, TP53 apoptosis effector | 0.00829162 |
| AZU1 | azurocidin 1 | 0.00825938 |
| RGCC | regulator of cell cycle | 0.00819733 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00817558 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.00817268 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0081495 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 0.00798471 |
| EZR | ezrin | 0.00796958 |
| ACKR3 | atypical chemokine receptor 3 | 0.0079119 |
| CRYAB | crystallin, alpha B | 0.00786324 |
| PEG3 | paternally expressed 3 | 0.00780394 |
| CD163 | CD163 molecule | 0.00773301 |
| PEG10 | paternally expressed 10 | 0.00768939 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00767451 |
| SIK1 | salt-inducible kinase 1 | 0.00766742 |
| IL32 | interleukin 32 | 0.00761838 |
| ELANE | elastase, neutrophil expressed | 0.00758666 |
| CNN3 | calponin 3, acidic | 0.00750617 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00744722 |
| TP63 | tumor protein p63 | 0.00737166 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.00730541 |
| MTCL1 | microtubule crosslinking factor 1 | 0.00727183 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00726704 |
| CCN2 | cellular communication network factor 2 | 0.00726394 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | 0.00724084 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00724071 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00721576 |
| CTSG | cathepsin G | 0.00708895 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00708047 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | 0.00705226 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.0070462 |
| EPHA2 | EPH receptor A2 | 0.00701554 |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.00690807 |
| PLK2 | polo-like kinase 2 | 0.0068843 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00687886 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | 0.00687393 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.00685755 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.0068357 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00682648 |
| NAV2 | neuron navigator 2 | 0.00679495 |
| ACTC1 | actin, alpha, cardiac muscle 1 | 0.00679402 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.00674397 |
| TTN | titin | 0.0067022 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00670003 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00669319 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.00668094 |
| PMP22 | peripheral myelin protein 22 | 0.00661686 |
| PDZD2 | PDZ domain containing 2 | 0.00659414 |
| MARCH3 | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase | 0.00658259 |
| DSC2 | desmocollin 2 | 0.0065593 |
| ITGB4 | integrin, beta 4 | 0.00655423 |
| TAGLN | transgelin | 0.00654941 |
| DSG3 | desmoglein 3 | 0.00654409 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00652527 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 | 0.00648229 |
| ZNF512B | zinc finger protein 512B | 0.00647746 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00645152 |
| TBX3 | T-box 3 | 0.0064483 |
| DENND5A | DENN/MADD domain containing 5A | 0.00644331 |
| ARL4A | ADP-ribosylation factor-like 4A | 0.00644174 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.00643632 |
| MIR22HG | MIR22 host gene | 0.00639142 |
| TNPO2 | transportin 2 | 0.00638946 |
| MAP7 | microtubule-associated protein 7 | 0.00638777 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00636481 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | 0.00633957 |
| CD14 | CD14 molecule | 0.00632096 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00630368 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00629683 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00628234 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.00624409 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00624337 |
| RIN2 | Ras and Rab interactor 2 | 0.00622024 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.00621353 |
| S100A9 | S100 calcium binding protein A9 | 0.00620364 |
| KRT23 | keratin 23, type I | 0.00617924 |
| TYROBP | TYRO protein tyrosine kinase binding protein | 0.00616405 |
| AHCYL1 | adenosylhomocysteinase-like 1 | 0.00615393 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00614278 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.00613868 |
| HBEGF | heparin-binding EGF-like growth factor | 0.00613472 |
| S100P | S100 calcium binding protein P | 0.00613461 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | 0.0061168 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00610059 |
| LYPD3 | LY6/PLAUR domain containing 3 | 0.00608625 |
| ACTA1 | actin, alpha 1, skeletal muscle | 0.00607814 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.00604416 |
| TLK2 | tousled-like kinase 2 | 0.00600022 |
| CCL13 | chemokine (C-C motif) ligand 13 | 0.00599582 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00599445 |
| MGP | matrix Gla protein | 0.00598461 |
| IL18 | interleukin 18 | 0.00598414 |
| XAF1 | XIAP associated factor 1 | 0.00598001 |
| FILIP1L | filamin A interacting protein 1-like | 0.00595765 |
| MSRA | methionine sulfoxide reductase A | 0.00592787 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00591603 |
| LIPG | lipase, endothelial | 0.00590907 |
| ANXA5 | annexin A5 | 0.00590038 |
| BLVRB | biliverdin reductase B | 0.00589574 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | 0.00587908 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00586498 |
| CKM | creatine kinase, muscle | 0.0058505 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | 0.00585044 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00585027 |
| PRTN3 | proteinase 3 | 0.00584981 |
| SLN | sarcolipin | 0.00584833 |
| FOXO1 | forkhead box O1 | 0.00584164 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.00584134 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.00583546 |
| JMJD6 | jumonji domain containing 6 | 0.00580035 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00578601 |
| CTSL | cathepsin L | 0.00575695 |
| TNNC1 | troponin C type 1 (slow) | 0.00575015 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00574234 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00572044 |
| CTSC | cathepsin C | 0.00571087 |
| CCDC86 | coiled-coil domain containing 86 | 0.00570225 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.0056965 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.00568806 |
| VWF | von Willebrand factor | 0.00568702 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00567948 |
| CLTB | clathrin, light chain B | 0.00566962 |
| CDK11A | cyclin-dependent kinase 11A | 0.00565659 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein | 0.00562554 |
| S100A11 | S100 calcium binding protein A11 | 0.0056179 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.00561607 |
| GPX3 | glutathione peroxidase 3 | 0.00561572 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | 0.00560626 |
| IRS2 | insulin receptor substrate 2 | 0.00560625 |
| KAZN | kazrin, periplakin interacting protein | 0.00560614 |
| TXLNA | taxilin alpha | 0.0055914 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00558349 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0055692 |
| UFM1 | ubiquitin-fold modifier 1 | 0.00552275 |
| TGFA | transforming growth factor, alpha | 0.00551927 |
| MT1X | metallothionein 1X | 0.0055192 |
| GPX2 | glutathione peroxidase 2 | 0.00551434 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | 0.00549543 |
| S100A4 | S100 calcium binding protein A4 | 0.00549108 |
| PAX6 | paired box 6 | 0.00548942 |
| CST3 | cystatin C | 0.00548106 |
| A2M | alpha-2-macroglobulin | 0.00547911 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.00547071 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00546289 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00546061 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00545312 |
| PRDX2 | peroxiredoxin 2 | 0.00543583 |
| PER3 | period circadian clock 3 | 0.00543254 |
| ADORA2B | adenosine A2b receptor | 0.00542812 |
| ZNF160 | zinc finger protein 160 | 0.00542375 |
| PKP1 | plakophilin 1 | 0.00542009 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.00540379 |
| CYBB | cytochrome b-245, beta polypeptide | 0.0053961 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.00539015 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.00538266 |
| MMP12 | matrix metallopeptidase 12 | 0.00536851 |
| SETD6 | SET domain containing 6 | 0.00536634 |
| MAU2 | MAU2 sister chromatid cohesion factor | 0.00536168 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00533962 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 0.00533765 |
| MED1 | mediator complex subunit 1 | 0.00532024 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | 0.00531904 |
| ADM | adrenomedullin | 0.00527236 |
| NCF2 | neutrophil cytosolic factor 2 | 0.00527038 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.00525982 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00525914 |
| HIST1H2BH | histone cluster 1, H2bh | 0.00524963 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00523257 |
| REXO2 | RNA exonuclease 2 | 0.00521624 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00521183 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00520634 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00516505 |
| S100A8 | S100 calcium binding protein A8 | 0.00516336 |
| ANK2 | ankyrin 2, neuronal | 0.00516241 |
| GLS | glutaminase | 0.00516077 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00515976 |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.00515454 |
| CHRNA1 | cholinergic receptor, nicotinic, alpha 1 (muscle) | 0.00515308 |
| TNNI2 | troponin I type 2 (skeletal, fast) | 0.00514436 |
| CCNA2 | cyclin A2 | 0.00514406 |
| C1ORF56 | chromosome 1 open reading frame 56 | 0.00512864 |
| BRD4 | bromodomain containing 4 | 0.00512199 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.0051181 |
| NES | nestin | 0.00508654 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00508471 |
| TNNC2 | troponin C type 2 (fast) | 0.00508317 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00507416 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.00507026 |
| PCDH9 | protocadherin 9 | 0.00505829 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00504754 |
| SPRR2B | small proline-rich protein 2B | 0.00504697 |
| BRD2 | bromodomain containing 2 | 0.00504608 |
| RAB8A | RAB8A, member RAS oncogene family | 0.00503096 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | 0.00502967 |
| CES1 | carboxylesterase 1 | 0.00502769 |
| TRIM22 | tripartite motif containing 22 | 0.00501547 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0050125 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.00500328 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00499852 |
| IRF9 | interferon regulatory factor 9 | 0.00499162 |
| METTL8 | methyltransferase like 8 | 0.00498539 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00497437 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00497338 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00496307 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) | 0.00496057 |
| JUND | jun D proto-oncogene | 0.00495279 |
| DDA1 | DET1 and DDB1 associated 1 | 0.00494244 |
| KRT7 | keratin 7, type II | 0.00493967 |
| GLUL | glutamate-ammonia ligase | 0.00492779 |
| IL1RN | interleukin 1 receptor antagonist | 0.0049173 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.00491583 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ADD3 | adducin 3 (gamma) | -0.012926 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.01257 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0118794 |
| THBS2 | thrombospondin 2 | -0.0110068 |
| NID2 | nidogen 2 (osteonidogen) | -0.0109452 |
| PLK1 | polo-like kinase 1 | -0.010235 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00983374 |
| DNTT | DNA nucleotidylexotransferase | -0.00965411 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00963218 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00901929 |
| HOXB7 | homeobox B7 | -0.00884347 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | -0.00848629 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00829611 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.00826891 |
| COL6A1 | collagen, type VI, alpha 1 | -0.00824066 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00811986 |
| ATF5 | activating transcription factor 5 | -0.00801474 |
| GRB14 | growth factor receptor-bound protein 14 | -0.007949 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00793 |
| RAB13 | RAB13, member RAS oncogene family | -0.00791455 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.0078878 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.00784113 |
| VCAN | versican | -0.00782182 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00777444 |
| XYLT1 | xylosyltransferase I | -0.0077579 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00773404 |
| RGS10 | regulator of G-protein signaling 10 | -0.00767273 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.00762622 |
| PWP1 | PWP1 homolog (S. cerevisiae) | -0.00762419 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00760969 |
| FABP6 | fatty acid binding protein 6, ileal | -0.00753337 |
| CEP57 | centrosomal protein 57kDa | -0.00750944 |
| MYRF | myelin regulatory factor | -0.00750119 |
| LAMB1 | laminin, beta 1 | -0.00742804 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.00742115 |
| RNF144A | ring finger protein 144A | -0.00740964 |
| DUSP6 | dual specificity phosphatase 6 | -0.00735196 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | -0.0073031 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00723348 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | -0.00720574 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.00703644 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | -0.00695036 |
| CDK1 | cyclin-dependent kinase 1 | -0.00694124 |
| SCG5 | secretogranin V | -0.00693516 |
| PROM1 | prominin 1 | -0.00689952 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -0.0068972 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -0.00687501 |
| CRYM | crystallin, mu | -0.00683172 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00675188 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00672897 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00670716 |
| MNS1 | meiosis-specific nuclear structural 1 | -0.00668923 |
| CTBP2 | C-terminal binding protein 2 | -0.00668303 |
| FGB | fibrinogen beta chain | -0.00667139 |
| BCHE | butyrylcholinesterase | -0.00664699 |
| SERINC5 | serine incorporator 5 | -0.00661178 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.00661125 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.00659514 |
| SNX7 | sorting nexin 7 | -0.0065882 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00658052 |
| PRAME | preferentially expressed antigen in melanoma | -0.00657926 |
| CLMN | calmin (calponin-like, transmembrane) | -0.0065572 |
| CFH | complement factor H | -0.00651096 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -0.00647939 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00646641 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 | -0.00646329 |
| INHBA | inhibin, beta A | -0.00644672 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -0.00644589 |
| SELENBP1 | selenium binding protein 1 | -0.00644272 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.00642988 |
| IPO13 | importin 13 | -0.00641994 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -0.0063423 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.00623169 |
| COL9A3 | collagen, type IX, alpha 3 | -0.00623168 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.0062247 |
| TWF1 | twinfilin actin binding protein 1 | -0.00619987 |
| MFAP2 | microfibrillar-associated protein 2 | -0.00618122 |
| IL1R1 | interleukin 1 receptor, type I | -0.00614068 |
| CD200 | CD200 molecule | -0.00611611 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | -0.00609838 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.00608876 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | -0.00606268 |
| LAT2 | linker for activation of T cells family, member 2 | -0.00604084 |
| THBS3 | thrombospondin 3 | -0.00603414 |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) | -0.00602987 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00601447 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.0060121 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00600268 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00588929 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00588416 |
| CHEK2 | checkpoint kinase 2 | -0.0058544 |
| COL10A1 | collagen, type X, alpha 1 | -0.00583646 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.00581764 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00581459 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | -0.00580262 |
| LUM | lumican | -0.00579536 |
| MGMT | O-6-methylguanine-DNA methyltransferase | -0.00579156 |
| CRYZ | crystallin, zeta (quinone reductase) | -0.00578025 |
| COL1A2 | collagen, type I, alpha 2 | -0.00577089 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00576804 |
| TMPO | thymopoietin | -0.00575578 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.00575123 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00574737 |
| ETNK1 | ethanolamine kinase 1 | -0.00574261 |
| LDB2 | LIM domain binding 2 | -0.00572773 |
| MLF1 | myeloid leukemia factor 1 | -0.00571878 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | -0.00569437 |
| C1ORF54 | chromosome 1 open reading frame 54 | -0.00568854 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.00567646 |
| NDN | necdin, melanoma antigen (MAGE) family member | -0.00567015 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.00566831 |
| RAD51AP1 | RAD51 associated protein 1 | -0.00565344 |
| CRIP2 | cysteine-rich protein 2 | -0.00562245 |
| MIPEP | mitochondrial intermediate peptidase | -0.00562198 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.00560303 |
| OVGP1 | oviductal glycoprotein 1, 120kDa | -0.00560127 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00559859 |
| PARPBP | PARP1 binding protein | -0.0055974 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00556452 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.00555298 |
| GSPT2 | G1 to S phase transition 2 | -0.00554058 |
| BGN | biglycan | -0.00551796 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | -0.00550625 |
| CCNE2 | cyclin E2 | -0.00548489 |
| L1CAM | L1 cell adhesion molecule | -0.00547241 |
| NVL | nuclear VCP-like | -0.00544591 |
| C6 | complement component 6 | -0.00543823 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00541167 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.00540973 |
| FAR2 | fatty acyl CoA reductase 2 | -0.00540806 |
| SIRT5 | sirtuin 5 | -0.00540508 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain | -0.00538909 |
| CLEC11A | C-type lectin domain family 11, member A | -0.00536484 |
| DEFB1 | defensin, beta 1 | -0.00536374 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00536361 |
| CUX2 | cut-like homeobox 2 | -0.00535016 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.0053444 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.00534193 |
| BRCA1 | breast cancer 1, early onset | -0.00533876 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00533303 |
| ADA | adenosine deaminase | -0.00530978 |
| RAB33A | RAB33A, member RAS oncogene family | -0.00530924 |
| HAL | histidine ammonia-lyase | -0.00530904 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.00530473 |
| HABP2 | hyaluronan binding protein 2 | -0.00529194 |
| TUBA1A | tubulin, alpha 1a | -0.00528896 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00528202 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.0052749 |
| LZTFL1 | leucine zipper transcription factor-like 1 | -0.00526003 |
| EVI2A | ecotropic viral integration site 2A | -0.00525832 |
| LSP1 | lymphocyte-specific protein 1 | -0.00525738 |
| CPB2 | carboxypeptidase B2 (plasma) | -0.00525679 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -0.00524978 |
| KIF11 | kinesin family member 11 | -0.00524285 |
| MAL | mal, T-cell differentiation protein | -0.00524232 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00524059 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | -0.00523996 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00523821 |
| EGR3 | early growth response 3 | -0.0052377 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.00523755 |
| CP | ceruloplasmin (ferroxidase) | -0.00522328 |
| NELL2 | NEL-like 2 (chicken) | -0.00522072 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -0.00521935 |
| PBK | PDZ binding kinase | -0.00521884 |
| GJB1 | gap junction protein, beta 1, 32kDa | -0.00521596 |
| ACVR1B | activin A receptor, type IB | -0.00521508 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -0.00520893 |
| PRDX3 | peroxiredoxin 3 | -0.00519748 |
| INA | internexin neuronal intermediate filament protein, alpha | -0.00518686 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00515153 |
| PHGDH | phosphoglycerate dehydrogenase | -0.00515083 |
| IFT81 | intraflagellar transport 81 | -0.00514033 |
| STC1 | stanniocalcin 1 | -0.0051371 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0051243 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00512204 |
| TMSB15A | thymosin beta 15a | -0.00512167 |
| TMEM243 | transmembrane protein 243, mitochondrial | -0.00511373 |
| HOXB6 | homeobox B6 | -0.00509793 |
| FMO3 | flavin containing monooxygenase 3 | -0.00505934 |
| CFB | complement factor B | -0.00505715 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00504986 |
| PON1 | paraoxonase 1 | -0.00504022 |
| MSH2 | mutS homolog 2 | -0.00503956 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | -0.00503367 |
| TDO2 | tryptophan 2,3-dioxygenase | -0.00501763 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.00499767 |
| DCT | dopachrome tautomerase | -0.00499399 |
| PF4 | platelet factor 4 | -0.00498933 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.00498752 |
| COL5A2 | collagen, type V, alpha 2 | -0.00498419 |
| SMAGP | small cell adhesion glycoprotein | -0.00495997 |
| HOXC6 | homeobox C6 | -0.00495561 |
| OLFML3 | olfactomedin-like 3 | -0.00495243 |
| BAX | BCL2-associated X protein | -0.00494898 |
| APCS | amyloid P component, serum | -0.00494111 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.00492103 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.00490495 |
| LTA4H | leukotriene A4 hydrolase | -0.0049004 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | -0.00489902 |
| TPM2 | tropomyosin 2 (beta) | -0.00489307 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00488256 |
| MECOM | MDS1 and EVI1 complex locus | -0.00488111 |
| TP53BP1 | tumor protein p53 binding protein 1 | -0.00486718 |
| CSTB | cystatin B (stefin B) | -0.00484946 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.00483663 |
| ZMYM3 | zinc finger, MYM-type 3 | -0.00483226 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00483198 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.00483178 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | -0.00482854 |
| CEL | carboxyl ester lipase | -0.00481923 |
| RNF130 | ring finger protein 130 | -0.00481551 |
| SLIT1 | slit homolog 1 (Drosophila) | -0.00481496 |
| STEAP1B | STEAP family member 1B | -0.00480711 |
| RAD54B | RAD54 homolog B (S. cerevisiae) | -0.00480451 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.004803 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00480106 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00479631 |
| LRRC15 | leucine rich repeat containing 15 | -0.00479101 |
| VWA1 | von Willebrand factor A domain containing 1 | -0.00477905 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | -0.00477857 |
| F12 | coagulation factor XII (Hageman factor) | -0.00477809 |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 | -0.00477704 |
| TFRC | transferrin receptor | -0.00475218 |
| TCTA | T-cell leukemia translocation altered | -0.00475008 |
| SPAG6 | sperm associated antigen 6 | -0.00474649 |
| GPR137B | G protein-coupled receptor 137B | -0.00474139 |
| APMAP | adipocyte plasma membrane associated protein | -0.00473898 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | -0.00473689 |
| ACP3 | acid phosphatase 3 | -0.00473324 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | -0.0047307 |
| VKORC1 | vitamin K epoxide reductase complex, subunit 1 | -0.00472377 |
| AMACR | alpha-methylacyl-CoA racemase | -0.00471901 |
| DIO1 | deiodinase, iodothyronine, type I | -0.00471553 |
| THOC5 | THO complex 5 | -0.00471396 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -0.00470483 |
| SYT1 | synaptotagmin I | -0.00467719 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | -0.00467457 |
| AQP9 | aquaporin 9 | -0.00467317 |
| BNC2 | basonuclin 2 | -0.0046612 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00465119 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00464833 |
| FA2H | fatty acid 2-hydroxylase | -0.00464281 |
| UNG | uracil-DNA glycosylase | -0.00464091 |
| FBXO5 | F-box protein 5 | -0.00463786 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | -0.00463061 |
| LCMT1 | leucine carboxyl methyltransferase 1 | -0.00461861 |
| CTSK | cathepsin K | -0.00461675 |
| LBR | lamin B receptor | -0.00460448 |
| ADRA2A | adrenoceptor alpha 2A | -0.00459805 |
