| Dataset | JASPAR Predicted Transcription Factor Targets |
| Category | genomics |
| Type | transcription factor |
| Description | MDS1 and EVI1 complex locus|The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] (NCBI Entrez Gene Database, 2122) |
| External Link | http://www.ncbi.nlm.nih.gov/gene/2122 |
| Similar Terms | |
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6 target genes of the MECOM transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
