| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | methyl CpG binding protein 2|DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. [provided by RefSeq, Jul 2009] (NCBI Entrez Gene Database, 4204) |
| External Link | https://ncbi.nlm.nih.gov/gene/4204 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the MECP2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTN | pleiotrophin | 0.013929 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.0134908 |
| GNAS | GNAS complex locus | 0.0133221 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0127258 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0122194 |
| KRT19 | keratin 19, type I | 0.0120429 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0111856 |
| EMP1 | epithelial membrane protein 1 | 0.010902 |
| FABP7 | fatty acid binding protein 7, brain | 0.0107843 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.0106995 |
| WIF1 | WNT inhibitory factor 1 | 0.0106314 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.0103724 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00980892 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00936935 |
| GPX3 | glutathione peroxidase 3 | 0.0093689 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00935079 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00884907 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00862823 |
| DOK5 | docking protein 5 | 0.00860427 |
| FOXG1 | forkhead box G1 | 0.00845462 |
| CP | ceruloplasmin (ferroxidase) | 0.00836139 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00820606 |
| MT1E | metallothionein 1E | 0.00803047 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00801274 |
| GET1 | guided entry of tail-anchored proteins factor 1 | 0.00791174 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00787576 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.0077424 |
| TGM2 | transglutaminase 2 | 0.00756347 |
| CPM | carboxypeptidase M | 0.00749002 |
| NIPSNAP2 | nipsnap homolog 2 | 0.00747212 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.00740948 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.00739883 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | 0.00737187 |
| TNC | tenascin C | 0.0072123 |
| TSPAN6 | tetraspanin 6 | 0.00715996 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00714383 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00706224 |
| TMEM100 | transmembrane protein 100 | 0.00700742 |
| PRKCB | protein kinase C, beta | 0.00693331 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00690035 |
| NAV3 | neuron navigator 3 | 0.00689514 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00689341 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00681856 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.00674787 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00674424 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00674029 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00670853 |
| DCK | deoxycytidine kinase | 0.00670479 |
| CNN3 | calponin 3, acidic | 0.00667101 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00663249 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00658953 |
| RLN1 | relaxin 1 | 0.00657533 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00646599 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | 0.00644008 |
| KRT15 | keratin 15, type I | 0.00642598 |
| THAP12 | THAP domain containing 12 | 0.0064099 |
| MAOA | monoamine oxidase A | 0.00638844 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00636735 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00635673 |
| NME5 | NME/NM23 family member 5 | 0.00634137 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00627977 |
| TRIB2 | tribbles pseudokinase 2 | 0.00623669 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00619952 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00618036 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00614782 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00609719 |
| PENK | proenkephalin | 0.00607745 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00606041 |
| TSPAN31 | tetraspanin 31 | 0.00600868 |
| CHRDL1 | chordin-like 1 | 0.00599323 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.00599163 |
| ITM2A | integral membrane protein 2A | 0.00597679 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00596955 |
| ZNF22 | zinc finger protein 22 | 0.00596177 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00595286 |
| HMGB2 | high mobility group box 2 | 0.00591199 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0058956 |
| EMX2 | empty spiracles homeobox 2 | 0.00588622 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00587947 |
| IFT57 | intraflagellar transport 57 | 0.00584685 |
| PEG10 | paternally expressed 10 | 0.005841 |
| PCP4 | Purkinje cell protein 4 | 0.00583386 |
| CORO2B | coronin, actin binding protein, 2B | 0.00582829 |
| SC5D | sterol-C5-desaturase | 0.0058034 |
| FAM3C | family with sequence similarity 3, member C | 0.00579834 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.00578679 |
| HNMT | histamine N-methyltransferase | 0.00578675 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.00578279 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.00575186 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.00574532 |
| EXOC5 | exocyst complex component 5 | 0.00574085 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00570403 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.00569216 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00566621 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.0056453 |
| FHL1 | four and a half LIM domains 1 | 0.00563836 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | 0.00559606 |
| TMEM126B | transmembrane protein 126B | 0.00558571 |
| SSX1 | synovial sarcoma, X breakpoint 1 | 0.00557769 |
| SH3BP4 | SH3-domain binding protein 4 | 0.00557614 |
| THSD7A | thrombospondin, type I, domain containing 7A | 0.00556716 |
| SPA17 | sperm autoantigenic protein 17 | 0.00556669 |
| LXN | latexin | 0.00556324 |
| COMMD10 | COMM domain containing 10 | 0.00554445 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00552617 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00549039 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0054855 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.00548411 |
| CHEK2 | checkpoint kinase 2 | 0.00547959 |
| ACP3 | acid phosphatase 3 | 0.00547181 |
| NPC2 | Niemann-Pick disease, type C2 | 0.00546508 |
| MYL12B | myosin, light chain 12B, regulatory | 0.00545711 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 0.00545566 |
| HSPA14 | heat shock 70kDa protein 14 | 0.00545174 |
| TMEM231 | transmembrane protein 231 | 0.00544666 |
| RSL24D1 | ribosomal L24 domain containing 1 | 0.00544649 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | 0.00542254 |
| FGG | fibrinogen gamma chain | 0.00541779 |
| KLF10 | Kruppel-like factor 10 | 0.00541317 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | 0.00539482 |
| RGS4 | regulator of G-protein signaling 4 | 0.00539295 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00539279 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00538853 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.00538481 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.0053623 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00535837 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00534768 |
| GLUL | glutamate-ammonia ligase | 0.00533368 |
| GSAP | gamma-secretase activating protein | 0.00533073 |
| METTL7A | methyltransferase like 7A | 0.0053225 |
| COPS7A | COP9 signalosome subunit 7A | 0.00530617 |
| TSPO | translocator protein (18kDa) | 0.00530295 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00524977 |
| C12ORF4 | chromosome 12 open reading frame 4 | 0.00524782 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00524511 |
| LRRC17 | leucine rich repeat containing 17 | 0.00524196 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00523394 |
| CCK | cholecystokinin | 0.00522302 |
| PFDN5 | prefoldin subunit 5 | 0.00520077 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.00519977 |
| RNF41 | ring finger protein 41, E3 ubiquitin protein ligase | 0.00519607 |
| MYBPC1 | myosin binding protein C, slow type | 0.0051948 |
| GTF2A2 | general transcription factor IIA, 2, 12kDa | 0.0051879 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.00518747 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.00517186 |
| PYROXD1 | pyridine nucleotide-disulphide oxidoreductase domain 1 | 0.00515176 |
| SCP2 | sterol carrier protein 2 | 0.00515058 |
| TMEM14B | transmembrane protein 14B | 0.00514529 |
| SFTPA2 | surfactant protein A2 | 0.00514332 |
| APOC1 | apolipoprotein C-I | 0.00513605 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.00511805 |
| PTK2B | protein tyrosine kinase 2 beta | 0.00511293 |
| GPX1 | glutathione peroxidase 1 | 0.00510117 |
| CLDN7 | claudin 7 | 0.00509403 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.00508657 |
| ADGRL4 | adhesion G protein-coupled receptor L4 | 0.00508606 |
| DEFB1 | defensin, beta 1 | 0.00508343 |
| SLC38A6 | solute carrier family 38, member 6 | 0.00508212 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00507879 |
| SELENOT | selenoprotein T | 0.00507865 |
| EFNB3 | ephrin-B3 | 0.00507155 |
| GLOD4 | glyoxalase domain containing 4 | 0.0050607 |
| IL33 | interleukin 33 | 0.00505209 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00505111 |
| MAMLD1 | mastermind-like domain containing 1 | 0.00503622 |
| PFN2 | profilin 2 | 0.00499292 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.00498784 |
| HP | haptoglobin | 0.00498583 |
| CD1E | CD1e molecule | 0.00498393 |
| C5ORF28 | chromosome 5 open reading frame 28 | 0.0049715 |
| PITX3 | paired-like homeodomain 3 | 0.00494248 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 | 0.00493372 |
| NDP | Norrie disease (pseudoglioma) | 0.00493038 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00492822 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | 0.00492622 |
| STK26 | serine/threonine protein kinase 26 | 0.00492212 |
| IL1R1 | interleukin 1 receptor, type I | 0.00490551 |
| GAP43 | growth associated protein 43 | 0.00490269 |
| STC1 | stanniocalcin 1 | 0.00490255 |
| NXT2 | nuclear transport factor 2-like export factor 2 | 0.00489314 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.00487882 |
| CHI3L2 | chitinase 3-like 2 | 0.00487511 |
| PNOC | prepronociceptin | 0.00486448 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | 0.00486404 |
| KRT13 | keratin 13, type I | 0.00486381 |
| SELENOF | selenoprotein F | 0.00484744 |
| CNIH1 | cornichon family AMPA receptor auxiliary protein 1 | 0.00484337 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | 0.00483701 |
| EFNB2 | ephrin-B2 | 0.00483537 |
| LIF | leukemia inhibitory factor | 0.00482888 |
| FBXO3 | F-box protein 3 | 0.00482063 |
| PLK2 | polo-like kinase 2 | 0.00479214 |
| TBPL1 | TBP-like 1 | 0.00477743 |
| PRDX3 | peroxiredoxin 3 | 0.00477089 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.00475712 |
| PCNXL4 | pecanex-like 4 (Drosophila) | 0.00475256 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.00475048 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.00474952 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.00472784 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.00470555 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.00469521 |
| DUT | deoxyuridine triphosphatase | 0.00469329 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | 0.00468559 |
| ATF1 | activating transcription factor 1 | 0.00468362 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.00467622 |
| SEPHS1 | selenophosphate synthetase 1 | 0.0046722 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 0.00466262 |
| BPIFA1 | BPI fold containing family A, member 1 | 0.00465726 |
| ADK | adenosine kinase | 0.00465553 |
| ZNF226 | zinc finger protein 226 | 0.00465494 |
| EFHC2 | EF-hand domain (C-terminal) containing 2 | 0.00465194 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | 0.00463349 |
| NMB | neuromedin B | 0.00463253 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00463024 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.00462516 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | 0.0046146 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | 0.00460988 |
| ALB | albumin | 0.0046042 |
| PEX19 | peroxisomal biogenesis factor 19 | 0.00460348 |
| KRT5 | keratin 5, type II | 0.00459889 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.00459356 |
| GTF2H5 | general transcription factor IIH, polypeptide 5 | 0.00458453 |
| POSTN | periostin, osteoblast specific factor | 0.00458246 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00456662 |
| TMEM135 | transmembrane protein 135 | 0.00455799 |
| SUMO3 | small ubiquitin-like modifier 3 | 0.00455131 |
| SOX17 | SRY (sex determining region Y)-box 17 | 0.00454386 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 | 0.00454003 |
| LEMD3 | LEM domain containing 3 | 0.00453423 |
| CCND2 | cyclin D2 | 0.00453389 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.00453178 |
| AZI2 | 5-azacytidine induced 2 | 0.00452961 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00452234 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00451941 |
| RPS5 | ribosomal protein S5 | 0.00449674 |
| RAB6A | RAB6A, member RAS oncogene family | 0.00449555 |
| PGC | progastricsin (pepsinogen C) | 0.0044941 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.00446714 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00446573 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.004465 |
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 | 0.00445805 |
| MRPL48 | mitochondrial ribosomal protein L48 | 0.00444325 |
| CES1 | carboxylesterase 1 | 0.0044421 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0044381 |
| MLF1 | myeloid leukemia factor 1 | 0.0044367 |
| MOB4 | MOB family member 4, phocein | 0.00442911 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | 0.00442835 |
| IPO5 | importin 5 | 0.00441603 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.00441351 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.00441194 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | -0.0181869 |
| STXBP2 | syntaxin binding protein 2 | -0.016783 |
| CA2 | carbonic anhydrase II | -0.0128439 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.011458 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.010533 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.010097 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00991585 |
| TGFB1 | transforming growth factor, beta 1 | -0.00941255 |
| PLXNB2 | plexin B2 | -0.00921745 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00901049 |
| NDRG1 | N-myc downstream regulated 1 | -0.00887506 |
| CST1 | cystatin SN | -0.00878223 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00877738 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00869426 |
| TYMP | thymidine phosphorylase | -0.00864153 |
| S100A12 | S100 calcium binding protein A12 | -0.00863902 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00850901 |
| QPRT | quinolinate phosphoribosyltransferase | -0.00850264 |
| NVL | nuclear VCP-like | -0.00850129 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00824435 |
| TUBA4A | tubulin, alpha 4a | -0.00820604 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -0.00820281 |
| COL7A1 | collagen, type VII, alpha 1 | -0.00811092 |
| CALML5 | calmodulin-like 5 | -0.00798824 |
| ACKR3 | atypical chemokine receptor 3 | -0.00792418 |
| S100A7 | S100 calcium binding protein A7 | -0.00790792 |
| BRCA1 | breast cancer 1, early onset | -0.00778681 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00777001 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.00774041 |
| RGS5 | regulator of G-protein signaling 5 | -0.0074142 |
| FSCN1 | fascin actin-bundling protein 1 | -0.00737062 |
| ACTN4 | actinin, alpha 4 | -0.00734487 |
| ZYX | zyxin | -0.00728241 |
| FERMT1 | fermitin family member 1 | -0.00724461 |
| GUCY2C | guanylate cyclase 2C | -0.00723141 |
| BGN | biglycan | -0.00721609 |
| SDC1 | syndecan 1 | -0.00717606 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.00712673 |
| VNN1 | vanin 1 | -0.0071203 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00695713 |
| HEPH | hephaestin | -0.00695692 |
| ECM1 | extracellular matrix protein 1 | -0.00693537 |
| XIC | X chromosome inactivation center | -0.00690952 |
| AEBP1 | AE binding protein 1 | -0.00690895 |
| TMEM176B | transmembrane protein 176B | -0.00686589 |
| CCNA2 | cyclin A2 | -0.00679268 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.00678986 |
| RIN2 | Ras and Rab interactor 2 | -0.0067152 |
| ADCY9 | adenylate cyclase 9 | -0.0066929 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00668836 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.00659696 |
| C5AR1 | complement component 5a receptor 1 | -0.00655546 |
| BMP4 | bone morphogenetic protein 4 | -0.00655084 |
| S100P | S100 calcium binding protein P | -0.00652983 |
| MX1 | MX dynamin-like GTPase 1 | -0.00651956 |
| MVP | major vault protein | -0.00643461 |
| MMP11 | matrix metallopeptidase 11 | -0.00643309 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00639503 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | -0.00638489 |
| JMJD6 | jumonji domain containing 6 | -0.00636687 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.00634783 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00632147 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.00631061 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -0.00630659 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00621425 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | -0.00615161 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00613542 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -0.00613168 |
| CLTB | clathrin, light chain B | -0.00605927 |
| CLIC3 | chloride intracellular channel 3 | -0.00602789 |
| IL32 | interleukin 32 | -0.00601794 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.00600641 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00598494 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | -0.00597707 |
| BRD4 | bromodomain containing 4 | -0.00595898 |
| L1CAM | L1 cell adhesion molecule | -0.00594578 |
| PIP | prolactin-induced protein | -0.0058812 |
| MPO | myeloperoxidase | -0.00586998 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00586753 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.00585125 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.00585117 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00583574 |
| CDK18 | cyclin-dependent kinase 18 | -0.00581005 |
| PDGFD | platelet derived growth factor D | -0.005807 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.00580002 |
| FGL2 | fibrinogen-like 2 | -0.00579653 |
| HOXC6 | homeobox C6 | -0.00579147 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00574046 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | -0.0057314 |
| IRF7 | interferon regulatory factor 7 | -0.00571925 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00569798 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00569633 |
| PLIN2 | perilipin 2 | -0.00567987 |
| CTSA | cathepsin A | -0.00566154 |
| FBLN2 | fibulin 2 | -0.00565215 |
| HOMER3 | homer scaffolding protein 3 | -0.00565171 |
| COL10A1 | collagen, type X, alpha 1 | -0.00563715 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | -0.00559374 |
| NCF2 | neutrophil cytosolic factor 2 | -0.00559347 |
| MFAP3L | microfibrillar-associated protein 3-like | -0.00558871 |
| MCOLN1 | mucolipin 1 | -0.00558867 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00558418 |
| CDA | cytidine deaminase | -0.00556472 |
| FPGS | folylpolyglutamate synthase | -0.00553533 |
| LAMP1 | lysosomal-associated membrane protein 1 | -0.00552801 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00551241 |
| MYO1D | myosin ID | -0.00550681 |
| TMEM45A | transmembrane protein 45A | -0.00550307 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | -0.00548601 |
| S100A8 | S100 calcium binding protein A8 | -0.00548468 |
| FILIP1L | filamin A interacting protein 1-like | -0.00544224 |
| NAV2 | neuron navigator 2 | -0.00542574 |
| MMP3 | matrix metallopeptidase 3 | -0.00538208 |
| KRT16 | keratin 16, type I | -0.00537295 |
| CARD10 | caspase recruitment domain family, member 10 | -0.00537097 |
| PTCH1 | patched 1 | -0.00536609 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.00536568 |
| RBM34 | RNA binding motif protein 34 | -0.0053497 |
| KLF2 | Kruppel-like factor 2 | -0.00533757 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | -0.00533687 |
| TUFM | Tu translation elongation factor, mitochondrial | -0.00533649 |
| DAP | death-associated protein | -0.00533312 |
| FAM13A | family with sequence similarity 13, member A | -0.00532782 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | -0.00531787 |
| TMEM63A | transmembrane protein 63A | -0.00530584 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) | -0.00529596 |
| DOCK9 | dedicator of cytokinesis 9 | -0.00529278 |
| PNPLA6 | patatin-like phospholipase domain containing 6 | -0.00526474 |
| LYZ | lysozyme | -0.00525935 |
| LONP1 | lon peptidase 1, mitochondrial | -0.00525925 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00523606 |
| CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | -0.00522736 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00520493 |
| CST4 | cystatin S | -0.00520203 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00517647 |
| ALDOA | aldolase A, fructose-bisphosphate | -0.00516752 |
| TSC2 | tuberous sclerosis 2 | -0.00516598 |
| NINL | ninein-like | -0.00514793 |
| COMP | cartilage oligomeric matrix protein | -0.00513657 |
| COLEC11 | collectin sub-family member 11 | -0.005134 |
| CYB5R2 | cytochrome b5 reductase 2 | -0.00512584 |
| TOX3 | TOX high mobility group box family member 3 | -0.00512355 |
| MX2 | MX dynamin-like GTPase 2 | -0.00510495 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 | -0.00510052 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | -0.00509784 |
| MGLL | monoglyceride lipase | -0.00509778 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.00509614 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | -0.00509049 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00509008 |
| PILRB | paired immunoglobin-like type 2 receptor beta | -0.00508408 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | -0.00506881 |
| IVL | involucrin | -0.00506596 |
| TFF1 | trefoil factor 1 | -0.00505012 |
| XAB2 | XPA binding protein 2 | -0.0050237 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.00502089 |
| METRN | meteorin, glial cell differentiation regulator | -0.00501612 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | -0.00500706 |
| SYNGR3 | synaptogyrin 3 | -0.00500257 |
| KIF2C | kinesin family member 2C | -0.00500217 |
| PTK2 | protein tyrosine kinase 2 | -0.00498803 |
| MINK1 | misshapen-like kinase 1 | -0.00498776 |
| MYO6 | myosin VI | -0.00497022 |
| C9ORF3 | chromosome 9 open reading frame 3 | -0.00496291 |
| INTS1 | integrator complex subunit 1 | -0.00495492 |
| MYRF | myelin regulatory factor | -0.00495267 |
| PMM2 | phosphomannomutase 2 | -0.00494722 |
| TUFT1 | tuftelin 1 | -0.0049447 |
| CD93 | CD93 molecule | -0.00494208 |
| THBS1 | thrombospondin 1 | -0.00493026 |
| MAT2A | methionine adenosyltransferase II, alpha | -0.00492691 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.00491761 |
| KAT2A | K(lysine) acetyltransferase 2A | -0.00491282 |
| RGS16 | regulator of G-protein signaling 16 | -0.00490652 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.00490556 |
| CSF1R | colony stimulating factor 1 receptor | -0.00490221 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | -0.00489833 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.00489684 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) | -0.00488218 |
| CLU | clusterin | -0.00488029 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00487474 |
| ZNF160 | zinc finger protein 160 | -0.00487117 |
| BMP2 | bone morphogenetic protein 2 | -0.00485815 |
| VARS | valyl-tRNA synthetase | -0.00485393 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00485145 |
| IL7R | interleukin 7 receptor | -0.00484667 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | -0.00484172 |
| COL1A1 | collagen, type I, alpha 1 | -0.00484158 |
| PSMC5 | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | -0.00482594 |
| RAPSN | receptor-associated protein of the synapse | -0.0048244 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00481969 |
| S100A9 | S100 calcium binding protein A9 | -0.00481761 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | -0.0048111 |
| NPIPA1 | nuclear pore complex interacting protein family, member A1 | -0.0048035 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00480094 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00479265 |
| CD14 | CD14 molecule | -0.00478533 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00478481 |
| SDC4 | syndecan 4 | -0.0047797 |
| RHOB | ras homolog family member B | -0.004775 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0047717 |
| COL15A1 | collagen, type XV, alpha 1 | -0.0047678 |
| KRT8 | keratin 8, type II | -0.00476594 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.00474541 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.00473124 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00472399 |
| HSPA4L | heat shock 70kDa protein 4-like | -0.00471771 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | -0.00471594 |
| MALT1 | MALT1 paracaspase | -0.00471394 |
| TMEM204 | transmembrane protein 204 | -0.00471288 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.00469938 |
| MPDZ | multiple PDZ domain protein | -0.00469096 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | -0.00468941 |
| SPRR2B | small proline-rich protein 2B | -0.00467206 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | -0.00467205 |
| ITGB4 | integrin, beta 4 | -0.00466374 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | -0.00466129 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00465176 |
| KRT20 | keratin 20, type I | -0.00465085 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | -0.0046465 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa | -0.00464615 |
| STK10 | serine/threonine kinase 10 | -0.00464446 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00464194 |
| TLE4 | transducin-like enhancer of split 4 | -0.00463949 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.00463395 |
| KLF11 | Kruppel-like factor 11 | -0.00463165 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | -0.00462761 |
| MRC2 | mannose receptor, C type 2 | -0.00461188 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | -0.00459756 |
| XPO6 | exportin 6 | -0.00459179 |
| DSG1 | desmoglein 1 | -0.00457999 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.0045531 |
| SAFB2 | scaffold attachment factor B2 | -0.00455212 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.00455086 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | -0.00453564 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.00453284 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00453172 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | -0.0045299 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.00452369 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00452069 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00451995 |
| LYPD3 | LY6/PLAUR domain containing 3 | -0.00451823 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00451774 |
| PXDC1 | PX domain containing 1 | -0.00451756 |
| HIP1R | huntingtin interacting protein 1 related | -0.00451347 |
| COCH | cochlin | -0.00451043 |
| GOLIM4 | golgi integral membrane protein 4 | -0.00450796 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.00450788 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00450575 |
| FLII | flightless I homolog (Drosophila) | -0.00450558 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | -0.00450475 |
