MED18 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description mediator complex subunit 18|MED18 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008] (NCBI Entrez Gene Database, 54797)
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Genes

85 genes differentially expressed following the MED18 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
FNDC10 fibronectin type III domain containing 10 2.21042
PDIK1L PDLIM1 interacting kinase 1 like 2.21042
METTL6 methyltransferase like 6 2.21042
SYNJ2 synaptojanin 2 2.21042
IPO13 importin 13 2.21042
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 2.21042
TINCR tissue differentiation-inducing non-protein coding RNA 2.21042
OSBPL5 oxysterol binding protein-like 5 2.21042
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 2.21042
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) 2.21042
ZNF226 zinc finger protein 226 2.21042
CCDC192 coiled-coil domain containing 192 2.21042
ZFTRAF1 zinc finger TRAF-type containing 1 2.21042
ECRG4 ECRG4 augurin precursor 2.21042
ARHGAP45 Rho GTPase activating protein 45 2.21042
H1-1 H1.1 linker histone, cluster member 2.21042
SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 2.21042
BTBD8 BTB (POZ) domain containing 8 2.21042
FKBP3 FK506 binding protein 3, 25kDa 2.21042
MEF2D myocyte enhancer factor 2D 2.21042
ABTB1 ankyrin repeat and BTB (POZ) domain containing 1 2.21042
ZSCAN16 zinc finger and SCAN domain containing 16 2.21042
ZNF546 zinc finger protein 546 2.21042
ZNF707 zinc finger protein 707 2.21042
CKLF chemokine-like factor 2.21042
ADAM28 ADAM metallopeptidase domain 28 2.21042
PCDHGA6 protocadherin gamma subfamily A, 6 2.21042
SH3GL1 SH3-domain GRB2-like 1 2.21042
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 2.21042
ZDHHC21 zinc finger, DHHC-type containing 21 2.21042
LMBRD2 LMBR1 domain containing 2 2.21042
KBTBD7 kelch repeat and BTB (POZ) domain containing 7 2.21042
WDR90 WD repeat domain 90 2.21042
ANGPTL1 angiopoietin-like 1 2.21042
RGPD1 RANBP2-like and GRIP domain containing 1 2.21042
ADAMTSL1 ADAMTS-like 1 2.21042
MYOM1 myomesin 1 2.21042
DRAM1 DNA-damage regulated autophagy modulator 1 2.12956
SAXO6 stabilizer of axonemal microtubules 6 2.10501
RGS6 regulator of G-protein signaling 6 2.09151
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 2.04754
PCDHB5 protocadherin beta 5 2.04754
GOLPH3 golgi phosphoprotein 3 (coat-protein) 2.04574

decreased expression

Symbol Name Standardized Value
SLC33A2 solute carrier family 33 member 2 -2.21042
LGALSL lectin, galactoside-binding-like -2.21042
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -2.21042
KANTR KDM5C adjacent non-coding transcript -2.21042
COA6 cytochrome c oxidase assembly factor 6 -2.21042
NRBF2 nuclear receptor binding factor 2 -2.21042
DUSP14 dual specificity phosphatase 14 -2.21042
TNNI3 troponin I type 3 (cardiac) -2.21042
SSC4D scavenger receptor cysteine rich family, 4 domains -2.21042
IDO1 indoleamine 2,3-dioxygenase 1 -2.21042
ADAL adenosine deaminase-like -2.21042
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -2.21042
ERLEC1 endoplasmic reticulum lectin 1 -2.21042
ZNF358 zinc finger protein 358 -2.21042
CDKL5 cyclin-dependent kinase-like 5 -2.21042
CNIH3 cornichon family AMPA receptor auxiliary protein 3 -2.21042
CEP85L centrosomal protein 85kDa-like -2.21042
WDCP WD repeat and coiled coil containing -2.21042
PBX2 pre-B-cell leukemia homeobox 2 -2.21042
CHMP3 charged multivesicular body protein 3 -2.21042
HESX1 HESX homeobox 1 -2.21042
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) -2.21042
SLC38A7 solute carrier family 38, member 7 -2.21042
RINT1 RAD50 interactor 1 -2.21042
KIF7 kinesin family member 7 -2.21042
TSPAN12 tetraspanin 12 -2.21042
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16 -2.21042
TMEM39A transmembrane protein 39A -2.21042
ZBTB46 zinc finger and BTB domain containing 46 -2.21042
CR1L complement component (3b/4b) receptor 1-like -2.21042
DCAF15 DDB1 and CUL4 associated factor 15 -2.21042
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -2.21042
CCDC51 coiled-coil domain containing 51 -2.21042
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 -2.18373
C1QBP complement component 1, q subcomponent binding protein -2.18373
C2ORF69 chromosome 2 open reading frame 69 -2.11771
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -2.06949
PTPN23 protein tyrosine phosphatase, non-receptor type 23 -2.06643
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) -2.06643
RBM15B RNA binding motif protein 15B -2.06643
SCAP SREBF chaperone -2.06643
KIAA2013 KIAA2013 -2.04574