| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | myocyte enhancer factor 2D|This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012] (NCBI Entrez Gene Database, 4209) |
| External Link | https://ncbi.nlm.nih.gov/gene/4209 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the MEF2D gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.0202175 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0145189 |
| PRAME | preferentially expressed antigen in melanoma | 0.0122814 |
| GNAS | GNAS complex locus | 0.0119989 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0117427 |
| CADM1 | cell adhesion molecule 1 | 0.0112052 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0107716 |
| PRKCA | protein kinase C, alpha | 0.0103972 |
| PLAT | plasminogen activator, tissue | 0.0103385 |
| TSPAN7 | tetraspanin 7 | 0.0102844 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 0.0100215 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | 0.00986715 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00959343 |
| COCH | cochlin | 0.00937034 |
| GDF15 | growth differentiation factor 15 | 0.0092735 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00900191 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00893673 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | 0.00869197 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00858916 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00849236 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00835454 |
| KYNU | kynureninase | 0.00825455 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00824857 |
| CHKB | choline kinase beta | 0.00817113 |
| ATF3 | activating transcription factor 3 | 0.00815181 |
| RNF167 | ring finger protein 167 | 0.00804755 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00782321 |
| MAL | mal, T-cell differentiation protein | 0.00778104 |
| ACP3 | acid phosphatase 3 | 0.00777097 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00761727 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00752981 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00752632 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.00742236 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 0.00736482 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.0073024 |
| ITGA6 | integrin, alpha 6 | 0.00720908 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00715852 |
| CNN3 | calponin 3, acidic | 0.00714057 |
| CD200 | CD200 molecule | 0.00708774 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00698616 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00693112 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00691207 |
| LCN2 | lipocalin 2 | 0.00679715 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.0067716 |
| COPS7A | COP9 signalosome subunit 7A | 0.00673875 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00669148 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.00668373 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0065933 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00653818 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 0.00653604 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.00650242 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0064841 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.00645126 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00644571 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.00642023 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00637025 |
| DCT | dopachrome tautomerase | 0.00637003 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.00628708 |
| HSPA12A | heat shock 70kDa protein 12A | 0.00626915 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00626741 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.00626059 |
| LARP6 | La ribonucleoprotein domain family, member 6 | 0.0062586 |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 | 0.00625279 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00621504 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.0061961 |
| GPM6B | glycoprotein M6B | 0.00615832 |
| RNF144A | ring finger protein 144A | 0.00613087 |
| DEFB1 | defensin, beta 1 | 0.00611636 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00610966 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00608497 |
| PCP4 | Purkinje cell protein 4 | 0.00606526 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | 0.00604425 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.0060413 |
| TUG1 | taurine up-regulated 1 (non-protein coding) | 0.00603648 |
| TMEM135 | transmembrane protein 135 | 0.0060205 |
| FZD6 | frizzled class receptor 6 | 0.00601642 |
| ZNHIT6 | zinc finger, HIT-type containing 6 | 0.00600491 |
| GANAB | glucosidase, alpha; neutral AB | 0.00599237 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 0.00598185 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00597454 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.00596626 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00595503 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.00595087 |
| COL9A2 | collagen, type IX, alpha 2 | 0.00594993 |
| GEM | GTP binding protein overexpressed in skeletal muscle | 0.0059469 |
| RGS4 | regulator of G-protein signaling 4 | 0.00592347 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.00591686 |
| TLK1 | tousled-like kinase 1 | 0.00591283 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | 0.00589774 |
| MMP7 | matrix metallopeptidase 7 | 0.00588862 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0058491 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00584267 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | 0.00583774 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00582943 |
| INAVA | innate immunity activator | 0.005819 |
| COL4A6 | collagen, type IV, alpha 6 | 0.00577789 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00577128 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00577012 |
| ANXA1 | annexin A1 | 0.00576916 |
| CST1 | cystatin SN | 0.00576579 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.00576083 |
| KYAT3 | kynurenine aminotransferase 3 | 0.00574883 |
| MOSPD1 | motile sperm domain containing 1 | 0.00574354 |
| ACTN1 | actinin, alpha 1 | 0.00573311 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.0057267 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.00570207 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00570029 |
| SNX10 | sorting nexin 10 | 0.00567914 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00567461 |
| RCAN1 | regulator of calcineurin 1 | 0.00567209 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.00566456 |
| JUNB | jun B proto-oncogene | 0.00565407 |
| ACTB | actin, beta | 0.00563205 |
| HOXB7 | homeobox B7 | 0.00561152 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00560688 |
| TRIB2 | tribbles pseudokinase 2 | 0.00560586 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00559836 |
| SRPX | sushi-repeat containing protein, X-linked | 0.0055936 |
| LAMC2 | laminin, gamma 2 | 0.0055839 |
| LYST | lysosomal trafficking regulator | 0.00556826 |
| NUMB | numb homolog (Drosophila) | 0.00555666 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00555299 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | 0.00554054 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.00553592 |
| KIF5C | kinesin family member 5C | 0.00552983 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.00552329 |
| GALC | galactosylceramidase | 0.00549987 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.00549011 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00548166 |
| IFRD1 | interferon-related developmental regulator 1 | 0.00547694 |
| PYGB | phosphorylase, glycogen; brain | 0.00547215 |
| TLK2 | tousled-like kinase 2 | 0.00547104 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00545803 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | 0.00545632 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.00545369 |
| CPD | carboxypeptidase D | 0.00544458 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00542581 |
| KLK11 | kallikrein-related peptidase 11 | 0.00541365 |
| GAS7 | growth arrest-specific 7 | 0.00540983 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00540843 |
| INHBB | inhibin, beta B | 0.00540572 |
| TSPYL5 | TSPY-like 5 | 0.00539458 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.00537062 |
| IRS2 | insulin receptor substrate 2 | 0.00536711 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) | 0.00535798 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00534608 |
| TGM2 | transglutaminase 2 | 0.00534202 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 0.00532241 |
| JAG1 | jagged 1 | 0.0053172 |
| PLBD1 | phospholipase B domain containing 1 | 0.00529512 |
| M6PR | mannose-6-phosphate receptor (cation dependent) | 0.00528514 |
| AK4 | adenylate kinase 4 | 0.00528384 |
| NCOA1 | nuclear receptor coactivator 1 | 0.00527863 |
| MLPH | melanophilin | 0.0052564 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00524287 |
| DNMBP | dynamin binding protein | 0.00522562 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.00522379 |
| DMXL1 | Dmx-like 1 | 0.00522031 |
| MMP8 | matrix metallopeptidase 8 | 0.00520674 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0052035 |
| PLD3 | phospholipase D family, member 3 | 0.00519578 |
| ATF4 | activating transcription factor 4 | 0.00518695 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0051856 |
| PLTP | phospholipid transfer protein | 0.00516476 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 | 0.00516034 |
| ATXN1 | ataxin 1 | 0.00515774 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.00515453 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00515286 |
| NCAM1 | neural cell adhesion molecule 1 | 0.00514797 |
| PFKP | phosphofructokinase, platelet | 0.00514777 |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 | 0.0051134 |
| PRKCH | protein kinase C, eta | 0.00510385 |
| CANX | calnexin | 0.00504652 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00504225 |
| NCKAP1L | NCK-associated protein 1-like | 0.00503541 |
| MEN1 | multiple endocrine neoplasia I | 0.00502731 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.00501813 |
| CCDC47 | coiled-coil domain containing 47 | 0.00500711 |
| RIMS3 | regulating synaptic membrane exocytosis 3 | 0.00499922 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0.00499739 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | 0.00499092 |
| PLAU | plasminogen activator, urokinase | 0.0049901 |
| C14ORF132 | chromosome 14 open reading frame 132 | 0.00498312 |
| PUM2 | pumilio RNA-binding family member 2 | 0.00497313 |
| KRT81 | keratin 81, type II | 0.00496764 |
| SMS | spermine synthase | 0.00496338 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0049582 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00493436 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.00492692 |
| ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 | 0.00492389 |
| STC1 | stanniocalcin 1 | 0.00492221 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.00491815 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | 0.0049156 |
| ZMPSTE24 | zinc metallopeptidase STE24 | 0.0048884 |
| NPY | neuropeptide Y | 0.00487912 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.0048768 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.00487463 |
| ANK2 | ankyrin 2, neuronal | 0.0048663 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.00486192 |
| DVL3 | dishevelled segment polarity protein 3 | 0.00484667 |
| SELL | selectin L | 0.00484281 |
| ITK | IL2-inducible T-cell kinase | 0.00482964 |
| CUL4B | cullin 4B | 0.00482478 |
| CD82 | CD82 molecule | 0.00482468 |
| TMOD1 | tropomodulin 1 | 0.00481057 |
| FLNA | filamin A, alpha | 0.00479843 |
| CNN1 | calponin 1, basic, smooth muscle | 0.00478941 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.00478937 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.00478876 |
| ALG6 | ALG6, alpha-1,3-glucosyltransferase | 0.00478329 |
| TNS3 | tensin 3 | 0.00478145 |
| SYT11 | synaptotagmin XI | 0.00477302 |
| RPIA | ribose 5-phosphate isomerase A | 0.00476355 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.00476287 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.00475857 |
| EIF3M | eukaryotic translation initiation factor 3, subunit M | 0.00475285 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00475232 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | 0.00475049 |
| UBAP2 | ubiquitin associated protein 2 | 0.00473876 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.0047347 |
| PEG10 | paternally expressed 10 | 0.00473119 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 0.0047067 |
| LBH | limb bud and heart development | 0.00470334 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.00469002 |
| AZIN1 | antizyme inhibitor 1 | 0.00468655 |
| STK38L | serine/threonine kinase 38 like | 0.00468619 |
| MFF | mitochondrial fission factor | 0.00467883 |
| SORD | sorbitol dehydrogenase | 0.00467437 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.00465813 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | 0.00465302 |
| WIF1 | WNT inhibitory factor 1 | 0.00465208 |
| MYO1C | myosin IC | 0.00464724 |
| C1ORF95 | chromosome 1 open reading frame 95 | 0.00464538 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00464278 |
| WLS | wntless Wnt ligand secretion mediator | 0.00463679 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.00463132 |
| LIF | leukemia inhibitory factor | 0.00462459 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.00461746 |
| PSEN1 | presenilin 1 | 0.00460763 |
| HDAC9 | histone deacetylase 9 | 0.00459448 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.00459205 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.00458812 |
| NCF2 | neutrophil cytosolic factor 2 | 0.00458335 |
| SARS1 | seryl-tRNA synthetase 1 | 0.00458127 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 | 0.00458057 |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) | 0.00456401 |
| MTIF2 | mitochondrial translational initiation factor 2 | 0.00456226 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00456181 |
| TLE4 | transducin-like enhancer of split 4 | 0.00454789 |
| TYRP1 | tyrosinase-related protein 1 | 0.00453266 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | -0.0169382 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.0152986 |
| CLU | clusterin | -0.0141465 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.013223 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.0129009 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.0125918 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0107775 |
| ADIRF | adipogenesis regulatory factor | -0.0103001 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0100791 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.0098131 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00977828 |
| TSPAN13 | tetraspanin 13 | -0.00947016 |
| CFH | complement factor H | -0.00906829 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.00886527 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00881588 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0087548 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00859361 |
| NNMT | nicotinamide N-methyltransferase | -0.00835286 |
| HOPX | HOP homeobox | -0.00828586 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00819884 |
| TAGLN | transgelin | -0.00792274 |
| AK1 | adenylate kinase 1 | -0.00790521 |
| METTL7A | methyltransferase like 7A | -0.00788723 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00787545 |
| BLNK | B-cell linker | -0.00777786 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00766845 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 | -0.00739756 |
| KRT18 | keratin 18, type I | -0.00732495 |
| INSR | insulin receptor | -0.0073094 |
| TNNI1 | troponin I type 1 (skeletal, slow) | -0.00713926 |
| CD320 | CD320 molecule | -0.00712782 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00709662 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00708444 |
| TFF1 | trefoil factor 1 | -0.00707913 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00705123 |
| IRX5 | iroquois homeobox 5 | -0.00700178 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | -0.00699173 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.00693472 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.0069282 |
| KLF6 | Kruppel-like factor 6 | -0.00688101 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.00683499 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00683154 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | -0.0067801 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00677888 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00673206 |
| TNNC1 | troponin C type 1 (slow) | -0.006713 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00671109 |
| SDC2 | syndecan 2 | -0.00663215 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00661158 |
| BMP2 | bone morphogenetic protein 2 | -0.00658602 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00658545 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00653671 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | -0.00652365 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00651725 |
| OLFM1 | olfactomedin 1 | -0.00651078 |
| HEBP2 | heme binding protein 2 | -0.00645122 |
| MMP3 | matrix metallopeptidase 3 | -0.00642134 |
| MB | myoglobin | -0.00641099 |
| ESR1 | estrogen receptor 1 | -0.00633031 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | -0.0062703 |
| ISYNA1 | inositol-3-phosphate synthase 1 | -0.00625124 |
| PON3 | paraoxonase 3 | -0.00624317 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00610714 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00607057 |
| MTCL1 | microtubule crosslinking factor 1 | -0.00605529 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.00605491 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | -0.00604466 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00602876 |
| KRT19 | keratin 19, type I | -0.00601379 |
| NOTCH2NL | notch 2 N-terminal like | -0.00599202 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00597779 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | -0.00597691 |
| PYCARD | PYD and CARD domain containing | -0.00596448 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00589285 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00587424 |
| HOXC6 | homeobox C6 | -0.00586796 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00584628 |
| AUTS2 | autism susceptibility candidate 2 | -0.00582643 |
| MFAP2 | microfibrillar-associated protein 2 | -0.00582081 |
| EGFL7 | EGF-like-domain, multiple 7 | -0.00581325 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | -0.00581287 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00580803 |
| IL7R | interleukin 7 receptor | -0.00580026 |
| SFTPB | surfactant protein B | -0.00576881 |
| FBN2 | fibrillin 2 | -0.0057528 |
| COMP | cartilage oligomeric matrix protein | -0.00570701 |
| CYB5R2 | cytochrome b5 reductase 2 | -0.00567864 |
| TNNT3 | troponin T type 3 (skeletal, fast) | -0.00567174 |
| TXNIP | thioredoxin interacting protein | -0.00567032 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00566648 |
| PCDH17 | protocadherin 17 | -0.00564336 |
| RTN2 | reticulon 2 | -0.00563989 |
| ZNF423 | zinc finger protein 423 | -0.00562943 |
| OPHN1 | oligophrenin 1 | -0.00559518 |
| IER3IP1 | immediate early response 3 interacting protein 1 | -0.00558908 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00556931 |
| TPM3 | tropomyosin 3 | -0.00554554 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00554303 |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B | -0.00553687 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -0.00553665 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.00551144 |
| ADGRE2 | adhesion G protein-coupled receptor E2 | -0.00551096 |
| GAMT | guanidinoacetate N-methyltransferase | -0.00550962 |
| PXDN | peroxidasin | -0.00548878 |
| C4BPA | complement component 4 binding protein, alpha | -0.00545926 |
| CISH | cytokine inducible SH2-containing protein | -0.00543811 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | -0.00543479 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00543419 |
| EVA1B | eva-1 homolog B (C. elegans) | -0.00542018 |
| ZNF721 | zinc finger protein 721 | -0.0054145 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00539989 |
| LTF | lactotransferrin | -0.00539865 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00539809 |
| SDC1 | syndecan 1 | -0.0053717 |
| SLC16A6 | solute carrier family 16, member 6 | -0.00535732 |
| ORM1 | orosomucoid 1 | -0.00535616 |
| ECI1 | enoyl-CoA delta isomerase 1 | -0.00535151 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00533071 |
| KLHL41 | kelch-like family member 41 | -0.00532743 |
| TGFB3 | transforming growth factor, beta 3 | -0.00531736 |
| ENG | endoglin | -0.00531004 |
| TMEM176B | transmembrane protein 176B | -0.00530791 |
| FAM13A | family with sequence similarity 13, member A | -0.00529322 |
| PBK | PDZ binding kinase | -0.00528883 |
| TMSB15A | thymosin beta 15a | -0.00528021 |
| ZNF586 | zinc finger protein 586 | -0.005269 |
| GPX4 | glutathione peroxidase 4 | -0.00526306 |
| TXN | thioredoxin | -0.00525407 |
| MDFIC | MyoD family inhibitor domain containing | -0.00524213 |
| NDUFS6 | NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) | -0.00523183 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00521035 |
| NTHL1 | nth endonuclease III-like 1 (E. coli) | -0.00520131 |
| ELOB | elongin B | -0.00519331 |
| MGP | matrix Gla protein | -0.00518679 |
| NXN | nucleoredoxin | -0.00518467 |
| ZNF160 | zinc finger protein 160 | -0.00516535 |
| POR | P450 (cytochrome) oxidoreductase | -0.00515043 |
| MACROD1 | MACRO domain containing 1 | -0.00511712 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.0051086 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00507774 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) | -0.00507487 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00506941 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.00504191 |
| CCND1 | cyclin D1 | -0.0050333 |
| VPREB1 | pre-B lymphocyte 1 | -0.00502344 |
| ELN | elastin | -0.00501355 |
| JAG2 | jagged 2 | -0.00499514 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00499169 |
| PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | -0.00498729 |
| GLCE | glucuronic acid epimerase | -0.00497862 |
| CCN2 | cellular communication network factor 2 | -0.00497672 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | -0.00495808 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0049529 |
| ZNHIT1 | zinc finger, HIT-type containing 1 | -0.00495056 |
| COX17 | COX17 cytochrome c oxidase copper chaperone | -0.0049454 |
| FPR1 | formyl peptide receptor 1 | -0.0049437 |
| TTN | titin | -0.00492641 |
| CCL21 | chemokine (C-C motif) ligand 21 | -0.00492598 |
| MRPL28 | mitochondrial ribosomal protein L28 | -0.00491757 |
| MXRA7 | matrix-remodelling associated 7 | -0.00491464 |
| ALDOA | aldolase A, fructose-bisphosphate | -0.00490971 |
| TYMP | thymidine phosphorylase | -0.00490204 |
| DSP | desmoplakin | -0.004899 |
| PLXND1 | plexin D1 | -0.00489425 |
| STAB1 | stabilin 1 | -0.00488175 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | -0.00488061 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00488049 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00486898 |
| RAB40B | RAB40B, member RAS oncogene family | -0.00485624 |
| TBCD | tubulin folding cofactor D | -0.00485335 |
| CYP2C8 | cytochrome P450, family 2, subfamily C, polypeptide 8 | -0.00484952 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.00484567 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.00483942 |
| TUSC3 | tumor suppressor candidate 3 | -0.00483484 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00482876 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.00482624 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -0.00482278 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | -0.00481746 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00481294 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | -0.004799 |
| GAB2 | GRB2-associated binding protein 2 | -0.0047988 |
| SOWAHC | sosondowah ankyrin repeat domain family member C | -0.0047985 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00479682 |
| RASIP1 | Ras interacting protein 1 | -0.00479241 |
| SIVA1 | SIVA1, apoptosis-inducing factor | -0.00477319 |
| BIN1 | bridging integrator 1 | -0.00475935 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00473523 |
| ALPL | alkaline phosphatase, liver/bone/kidney | -0.00472695 |
| ASMTL | acetylserotonin O-methyltransferase-like | -0.0047221 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0047102 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.00470861 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.00470691 |
| TPM2 | tropomyosin 2 (beta) | -0.00470502 |
| SELENOW | selenoprotein W | -0.00470132 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00470112 |
| PROS1 | protein S (alpha) | -0.00469153 |
| PDZK1 | PDZ domain containing 1 | -0.00469137 |
| ALB | albumin | -0.00469058 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | -0.0046891 |
| ARMT1 | acidic residue methyltransferase 1 | -0.00468503 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) | -0.00468327 |
| TNNC2 | troponin C type 2 (fast) | -0.00467668 |
| LRP2 | low density lipoprotein receptor-related protein 2 | -0.00467349 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 | -0.00467348 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 | -0.00466169 |
| CLEC3B | C-type lectin domain family 3, member B | -0.00465271 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.00465148 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00465103 |
| MYOT | myotilin | -0.00463886 |
| TMEM14A | transmembrane protein 14A | -0.00463741 |
| DSTN | destrin (actin depolymerizing factor) | -0.00463381 |
| ANOS1 | anosmin 1 | -0.00463028 |
| GUSB | glucuronidase, beta | -0.00461537 |
| HBP1 | HMG-box transcription factor 1 | -0.00461113 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) | -0.00460754 |
| HPR | haptoglobin-related protein | -0.0046002 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | -0.00459767 |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 | -0.0045889 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00458809 |
| CD52 | CD52 molecule | -0.00457882 |
| CRLF1 | cytokine receptor-like factor 1 | -0.0045726 |
| HYI | hydroxypyruvate isomerase (putative) | -0.00456947 |
| EPHB4 | EPH receptor B4 | -0.00456873 |
| REX1BD | required for excision 1-B domain containing | -0.00455684 |
| CBX1 | chromobox homolog 1 | -0.00455462 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.00454637 |
| DSE | dermatan sulfate epimerase | -0.00452864 |
| CEP43 | centrosomal protein 43 | -0.00449907 |
| TCTN2 | tectonic family member 2 | -0.0044916 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 | -0.00448365 |
| CHODL | chondrolectin | -0.00447722 |
| PON1 | paraoxonase 1 | -0.00447695 |
| TSEN34 | TSEN34 tRNA splicing endonuclease subunit | -0.00446965 |
| SYNC | syncoilin, intermediate filament protein | -0.00446834 |
| TK1 | thymidine kinase 1, soluble | -0.00444781 |
| FBXW12 | F-box and WD repeat domain containing 12 | -0.00444719 |
| GTSE1 | G-2 and S-phase expressed 1 | -0.00444358 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.00444147 |
| INSM1 | insulinoma-associated 1 | -0.00443087 |
| PRR11 | proline rich 11 | -0.0044139 |
| MRPL11 | mitochondrial ribosomal protein L11 | -0.00440917 |
| MYL6B | myosin, light chain 6B, alkali, smooth muscle and non-muscle | -0.00438097 |
| RAB13 | RAB13, member RAS oncogene family | -0.00437491 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.00436736 |
| UGT2B4 | UDP glucuronosyltransferase 2 family, polypeptide B4 | -0.00436715 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa | -0.00436497 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | -0.00435846 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | -0.00435645 |
| DTYMK | deoxythymidylate kinase (thymidylate kinase) | -0.0043485 |
| SELENBP1 | selenium binding protein 1 | -0.00434787 |
