MEF2D Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description myocyte enhancer factor 2D|This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012] (NCBI Entrez Gene Database, 4209)
External Link http://www.ncbi.nlm.nih.gov/gene/4209
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36 interacting proteins for MEF2D from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
APP amyloid beta (A4) precursor protein
ASCL1 achaete-scute family bHLH transcription factor 1
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
CABIN1 calcineurin binding protein 1
CARM1 coactivator-associated arginine methyltransferase 1
CASP7 caspase 7, apoptosis-related cysteine peptidase
CDK5 cyclin-dependent kinase 5
CDK6 cyclin-dependent kinase 6
COPS5 COP9 signalosome subunit 5
EP300 E1A binding protein p300
HDAC1 histone deacetylase 1
HDAC3 histone deacetylase 3
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HIRA histone cell cycle regulator
HTT huntingtin
KAT2B K(lysine) acetyltransferase 2B
KMT2D lysine (K)-specific methyltransferase 2D
MAPK11 mitogen-activated protein kinase 11
MAPK14 mitogen-activated protein kinase 14
MAPK7 mitogen-activated protein kinase 7
MEF2A myocyte enhancer factor 2A
MEF2C myocyte enhancer factor 2C
MEN1 multiple endocrine neoplasia I
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
PKM pyruvate kinase, muscle
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRMT5 protein arginine methyltransferase 5
RBBP5 retinoblastoma binding protein 5
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SP1 Sp1 transcription factor
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
UBC ubiquitin C
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta