MEFENAMIC ACID Gene Set

Dataset DGIdb Drug Targets 2026
Category physical interactions
Type drug
Description An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis. (Chemical Entities of Biological Interest Ontology, CHEBI_6717)
External Link https://dgidb.org/results?searchType=drug&searchTerms=MEFENAMIC ACID
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Genes

14 interacting proteins for the MEFENAMIC ACID drug from theDGIdb Drug Targets 2026 dataset.

Symbol Name Standardized Value
TRPM3 transient receptor potential cation channel, subfamily M, member 3 0.157536
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.151234
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.11371
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.111202
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.092216
TDP1 tyrosyl-DNA phosphodiesterase 1 0.0609816
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 0.0564307
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0255463
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.0173434
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.0158526
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 0.0129481
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 0.012376
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.00853466
NFE2L2 nuclear factor, erythroid 2-like 2 0.00449567