MEIS1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description Meis homeobox 1|Homeobox genes, of which the most well-characterized category is represented by the HOX genes, play a crucial role in normal development. In addition, several homeoproteins are involved in neoplasia. This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4211)
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Genes

364 genes differentially expressed following the MEIS1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
C10ORF62 chromosome 10 open reading frame 62 2.92785
PDILT protein disulfide isomerase-like, testis expressed 2.92785
GPR4 G protein-coupled receptor 4 2.92785
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 2.92785
SIX1 SIX homeobox 1 2.92785
OR5P3 olfactory receptor, family 5, subfamily P, member 3 2.92785
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) 2.92785
TMPRSS11A transmembrane protease, serine 11A 2.92785
CD6 CD6 molecule 2.92785
CARD18 caspase recruitment domain family, member 18 2.92785
FGD2 FYVE, RhoGEF and PH domain containing 2 2.92785
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 2.92785
TAS2R5 taste receptor, type 2, member 5 2.92785
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 2.92785
CATSPER1 cation channel, sperm associated 1 2.92785
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 2.92785
DAO D-amino-acid oxidase 2.92785
CHRD chordin 2.92785
PCDHA3 protocadherin alpha 3 2.92785
FAM170B family with sequence similarity 170, member B 2.92785
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 2.92785
LIPC lipase, hepatic 2.92785
ATP13A4 ATPase type 13A4 2.92785
LOC390937 Ets2 repressor factor-like 2.92785
GRXCR1 glutaredoxin, cysteine rich 1 2.92785
PI15 peptidase inhibitor 15 2.92785
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 2.92785
CD209 CD209 molecule 2.92785
TRPV3 transient receptor potential cation channel, subfamily V, member 3 2.92785
TRPV6 transient receptor potential cation channel, subfamily V, member 6 2.92785
TRPV5 transient receptor potential cation channel, subfamily V, member 5 2.92785
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 2.92785
LCN12 lipocalin 12 2.92785
LCN15 lipocalin 15 2.92785
UBA7 ubiquitin-like modifier activating enzyme 7 2.92785
CRX cone-rod homeobox 2.92785
TMEM143 transmembrane protein 143 2.92785
MYO1G myosin IG 2.92785
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 2.92785
CXCL2 chemokine (C-X-C motif) ligand 2 2.92785
SLC9C2 solute carrier family 9, member C2 (putative) 2.92785
MILR1 mast cell immunoglobulin-like receptor 1 2.92785
PEAR1 platelet endothelial aggregation receptor 1 2.92785
C8ORF48 chromosome 8 open reading frame 48 2.92785
SLC25A45 solute carrier family 25, member 45 2.92785
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 2.92785
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 2.92785
DIRAS2 DIRAS family, GTP-binding RAS-like 2 2.92785
NUGGC nuclear GTPase, germinal center associated 2.92785
GPR21 G protein-coupled receptor 21 2.92785
ARSF arylsulfatase F 2.92785
SLC39A4 solute carrier family 39 (zinc transporter), member 4 2.92785
CSNK2A3 casein kinase 2, alpha 3 polypeptide 2.92785
MSX1 msh homeobox 1 2.92785
SPMIP10 sperm microtubule inner protein 10 2.92785
ERFE erythroferrone 2.92785
DNAAF8 dynein axonemal assembly factor 8 2.92785
H3-5 H3.5 histone 2.92785
STYXL2 serine/threonine/tyrosine interacting like 2 2.92785
MYG1 MYG1 exonuclease 2.92785
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2 2.92785
TMOD4 tropomodulin 4 (muscle) 2.92785
OTOF otoferlin 2.92785
UNC93A unc-93 homolog A (C. elegans) 2.92785
AANAT aralkylamine N-acetyltransferase 2.92785
SPRY3 sprouty homolog 3 (Drosophila) 2.92785
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 2.92785
TERB1 telomere repeat binding bouquet formation protein 1 2.92785
LINC02268 long intergenic non-protein coding RNA 2268 2.92785
LRRC8C-DT LRRC8C divergent transcript 2.92785
NOTCH2NLB notch 2 N-terminal like B 2.92785
H2BK1 H2B.K variant histone 1 2.92785
OOSP4A oocyte secreted protein family member 4A 2.92785
LOC124903233 uncharacterized LOC124903233 2.92785
MYMK myomaker, myoblast fusion factor 2.92785
TMEM272 transmembrane protein 272 2.92785
ARMH2 armadillo like helical domain containing 2 2.92785
TMEM225B transmembrane protein 225B 2.92785
TEX13C TEX13 family member C 2.92785
STX11 syntaxin 11 2.92785
SPATA31C2 SPATA31 subfamily C, member 2 2.92785
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B 2.92785
ZAR1L zygote arrest 1-like 2.92785
VCX3A variable charge, X-linked 3A 2.92785
ALG10B ALG10B, alpha-1,2-glucosyltransferase 2.92785
LRRC3C leucine rich repeat containing 3C 2.92785
UTS2 urotensin 2 2.92785
GLIPR1L2 GLI pathogenesis-related 1 like 2 2.92785
TPTE transmembrane phosphatase with tensin homology 2.92785
TLR7 toll-like receptor 7 2.92785
NHLRC4 NHL repeat containing 4 2.92785
CCDC92 coiled-coil domain containing 92 2.92785
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 2.92785
TMEM119 transmembrane protein 119 2.92785
ASIC4 acid sensing (proton gated) ion channel family member 4 2.92785
TMEM40 transmembrane protein 40 2.92785
MIOX myo-inositol oxygenase 2.92785
XKRX XK, Kell blood group complex subunit-related, X-linked 2.92785
TSPAN1 tetraspanin 1 2.92785
ZNF705A zinc finger protein 705A 2.92785
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 2.92785
ARL14EPL ADP-ribosylation factor-like 14 effector protein-like 2.92785
OSTN osteocrin 2.92785
MROH5 maestro heat-like repeat family member 5 2.92785
DLK1 delta-like 1 homolog (Drosophila) 2.92785
SOAT2 sterol O-acyltransferase 2 2.92785
OR2AT4 olfactory receptor, family 2, subfamily AT, member 4 2.92785
VNN1 vanin 1 2.92785
GAL3ST2 galactose-3-O-sulfotransferase 2 2.92785
FNDC1 fibronectin type III domain containing 1 2.92785
LRRC46 leucine rich repeat containing 46 2.92785
MRLN myoregulin 2.92785
RGS13 regulator of G-protein signaling 13 2.92785
TESPA1 thymocyte expressed, positive selection associated 1 2.92785
UBQLNL ubiquilin-like 2.92785
TNR tenascin R 2.92785
GOLGA6D golgin A6 family, member D 2.92785
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 2.92785
CD5L CD5 molecule-like 2.92785
ENDOU endonuclease, polyU-specific 2.92785
NACA2 nascent polypeptide-associated complex alpha subunit 2 2.92785
PYHIN1 pyrin and HIN domain family, member 1 2.92785
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 2.92785
SLITRK1 SLIT and NTRK-like family, member 1 2.92785
ADIRF adipogenesis regulatory factor 2.92785
OR13A1 olfactory receptor, family 13, subfamily A, member 1 2.92785
SLFN12L schlafen family member 12-like 2.92785
PRSS55 protease, serine, 55 2.92785
PDCD11 programmed cell death 11 2.92785
FIGLA folliculogenesis specific basic helix-loop-helix 2.92785
HSF4 heat shock transcription factor 4 2.92785
SMYD3 SET and MYND domain containing 3 2.92785
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6 2.92785
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 2.92785
DRD5 dopamine receptor D5 2.92785
PCDHGA4 protocadherin gamma subfamily A, 4 2.92785
RGS8 regulator of G-protein signaling 8 2.92785
DCN decorin 2.92785
ORM2 orosomucoid 2 2.92785
RBBP8NL RBBP8 N-terminal like 2.92785
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 2.92785
LAMB4 laminin, beta 4 2.92785
PLA2G5 phospholipase A2, group V 2.92785
DRC1 dynein regulatory complex subunit 1 2.92785
TEX29 testis expressed 29 2.92785
ZNF835 zinc finger protein 835 2.92785
GOLGA8O golgin A8 family, member O 2.92785
IP6K3 inositol hexakisphosphate kinase 3 2.92785
DLX3 distal-less homeobox 3 2.92785
VAV1 vav 1 guanine nucleotide exchange factor 2.92785
MUC17 mucin 17, cell surface associated 2.92785
IL10 interleukin 10 2.92785
RGCC regulator of cell cycle 2.92785
PLA1A phospholipase A1 member A 2.92785
FBXO47 F-box protein 47 2.92785
IGF2 insulin-like growth factor 2 2.92785
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 2.92785
TG thyroglobulin 2.92785
TPPP2 tubulin polymerization-promoting protein family member 2 2.92785
SCNN1B sodium channel, non voltage gated 1 beta subunit 2.92785
SIGLEC11 sialic acid binding Ig-like lectin 11 2.92785
ART1 ADP-ribosyltransferase 1 2.92785
PATE2 prostate and testis expressed 2 2.92785
TMPRSS15 transmembrane protease, serine 15 2.92785
SMCO3 single-pass membrane protein with coiled-coil domains 3 2.92785
MEIG1 meiosis/spermiogenesis associated 1 2.92785
LRRC31 leucine rich repeat containing 31 2.92785
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 2.92785
FXYD3 FXYD domain containing ion transport regulator 3 2.92785
MNX1 motor neuron and pancreas homeobox 1 2.92785
MAGEC3 melanoma antigen family C3 2.92785
IFITM10 interferon induced transmembrane protein 10 2.92785
RHOJ ras homolog family member J 2.92785
MSANTD1 Myb/SANT-like DNA-binding domain containing 1 2.92785
ADRA1B adrenoceptor alpha 1B 2.92785
BTBD19 BTB (POZ) domain containing 19 2.92785
SLC38A3 solute carrier family 38, member 3 2.92785
OIT3 oncoprotein induced transcript 3 2.92785
SLC10A5 solute carrier family 10, member 5 2.92785
LOC102724877 uncharacterized LOC102724877 2.92785
CLCA4 chloride channel accessory 4 2.92785
RHAG Rh-associated glycoprotein 2.92785
BIN2 bridging integrator 2 2.92785
FGF9 fibroblast growth factor 9 2.92785
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 2.92785
NR4A3 nuclear receptor subfamily 4, group A, member 3 2.92785
OR4D1 olfactory receptor, family 4, subfamily D, member 1 2.8924
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 2.88192
TEX46 testis expressed 46 2.87291
QRICH2 glutamine rich 2 2.87291
ADORA2B adenosine A2b receptor 2.87291
OSBPL7 oxysterol binding protein-like 7 2.87291
SOX21 SRY (sex determining region Y)-box 21 2.87291
AKR1D1 aldo-keto reductase family 1, member D1 2.87291
PCBP3 poly(rC) binding protein 3 2.7704
MINK1 misshapen-like kinase 1 2.76572
DAP3 death associated protein 3 2.71029
TANGO6 transport and golgi organization 6 homolog (Drosophila) 2.70969
INSIG2 insulin induced gene 2 2.69306
CREB1 cAMP responsive element binding protein 1 2.69306
MINDY4B MINDY family member 4B 2.67417
PLA2G15 phospholipase A2, group XV 2.6683
SIRT7 sirtuin 7 2.6683
UCMA upper zone of growth plate and cartilage matrix associated 2.59459
KIF18B kinesin family member 18B 2.53673
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 2.51496
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 2.50405
DGCR2 DiGeorge syndrome critical region gene 2 2.48485
CD27 CD27 molecule 2.47263
ANKRD40 ankyrin repeat domain 40 2.45263
PJVK pejvakin 2.45263
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 2.44898
TMEM131 transmembrane protein 131 2.44326
ASIC1 acid sensing (proton gated) ion channel 1 2.42784
EVC Ellis van Creveld protein 2.42078
HACD2 3-hydroxyacyl-CoA dehydratase 2 2.39744
FRMPD1 FERM and PDZ domain containing 1 2.39095
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 2.39095
FABP12 fatty acid binding protein 12 2.38534
FGF18 fibroblast growth factor 18 2.38534
YY2 YY2 transcription factor 2.38534
GPATCH4 G patch domain containing 4 2.38225
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.36989
CADPS Ca++-dependent secretion activator 2.36081
SPEN spen family transcriptional repressor 2.34905
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa 2.30773
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 2.30671
MIPEP mitochondrial intermediate peptidase 2.28793
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 2.28221
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 2.28221
HDAC11 histone deacetylase 11 2.2762
MEPCE methylphosphate capping enzyme 2.26567
MT1F metallothionein 1F 2.25399
SMG6 SMG6 nonsense mediated mRNA decay factor 2.24557
RAMP2 receptor (G protein-coupled) activity modifying protein 2 2.22934
PSENEN presenilin enhancer gamma secretase subunit 2.22519
MRFAP1L1 Morf4 family associated protein 1-like 1 2.22049
SEC24C SEC24 family member C 2.22021
CLU clusterin 2.21375
FOXL2NB FOXL2 neighbor 2.20811
REST RE1-silencing transcription factor 2.2063
CRYM crystallin, mu 2.1927
PHTF1 putative homeodomain transcription factor 1 2.18373
WDR36 WD repeat domain 36 2.15953
TNNC1 troponin C type 1 (slow) 2.15005
SLC38A10 solute carrier family 38, member 10 2.13915
PDIK1L PDLIM1 interacting kinase 1 like 2.11257
UBE2D1 ubiquitin-conjugating enzyme E2D 1 2.11234
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 2.10408
TXNRD3 thioredoxin reductase 3 2.08071
ZNF718 zinc finger protein 718 2.06171
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa 2.05884
CXXC1 CXXC finger protein 1 2.04623
ZNF695 zinc finger protein 695 2.02433
SKAP1 src kinase associated phosphoprotein 1 2.02419
RCAN2 regulator of calcineurin 2 2.00232
B3GAT2 beta-1,3-glucuronyltransferase 2 2.00146

decreased expression

Symbol Name Standardized Value
SYS1 Sys1 golgi trafficking protein -2.92785
XG Xg blood group -2.92785
BTD biotinidase -2.92785
SNAP25 synaptosomal-associated protein, 25kDa -2.92785
DSCAM Down syndrome cell adhesion molecule -2.92785
SLC45A1 solute carrier family 45, member 1 -2.92785
PCDHAC1 protocadherin alpha subfamily C, 1 -2.92785
INKA1 inka box actin regulator 1 -2.92785
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 -2.92785
TATDN3 TatD DNase domain containing 3 -2.8767
NTSR1 neurotensin receptor 1 (high affinity) -2.87291
OVGP1 oviductal glycoprotein 1, 120kDa -2.87291
ALLC allantoicase -2.87291
PTGER3 prostaglandin E receptor 3 (subtype EP3) -2.87291
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) -2.87291
SYNM synemin, intermediate filament protein -2.87291
AVP arginine vasopressin -2.87291
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -2.87291
CRB1 crumbs family member 1, photoreceptor morphogenesis associated -2.87291
PRSS50 protease, serine, 50 -2.87291
PDCD1 programmed cell death 1 -2.87291
SYCP1 synaptonemal complex protein 1 -2.87291
IZUMO1 izumo sperm-egg fusion 1 -2.87291
HSPB6 heat shock protein, alpha-crystallin-related, B6 -2.87291
TMEM179 transmembrane protein 179 -2.87291
C2CD2L C2CD2-like -2.87291
LRRN4 leucine rich repeat neuronal 4 -2.87291
CFAP206 cilia and flagella associated protein 206 -2.87291
OR52N2 olfactory receptor, family 52, subfamily N, member 2 -2.87291
CIMAP2 ciliary microtubule associated protein 2 -2.87291
NSG2 neuronal vesicle trafficking associated 2 -2.87291
FGF4 fibroblast growth factor 4 -2.87291
OVOL1 ovo-like zinc finger 1 -2.87291
VSX2 visual system homeobox 2 -2.87291
OTOP2 otopetrin 2 -2.87291
ARID5B AT rich interactive domain 5B (MRF1-like) -2.82438
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -2.76483
LIMS2 LIM and senescent cell antigen-like domains 2 -2.76253
BCL2L11 BCL2-like 11 (apoptosis facilitator) -2.76253
VWA5B1 von Willebrand factor A domain containing 5B1 -2.76253
TGFBR3L transforming growth factor, beta receptor III-like -2.73613
SUN2 Sad1 and UNC84 domain containing 2 -2.73613
TBC1D10A TBC1 domain family, member 10A -2.71668
SREBF2 sterol regulatory element binding transcription factor 2 -2.71029
RGS7BP regulator of G-protein signaling 7 binding protein -2.69917
CNTN1 contactin 1 -2.65246
ALG8 ALG8, alpha-1,3-glucosyltransferase -2.6225
ERGIC2 ERGIC and golgi 2 -2.53462
PRMT3 protein arginine methyltransferase 3 -2.51992
KRABD4 KRAB domain containing 4 -2.50007
PLS3 plastin 3 -2.49491
NECTIN3 nectin cell adhesion molecule 3 -2.47924
DONSON downstream neighbor of SON -2.45762
AMOTL2 angiomotin like 2 -2.45762
MBP myelin basic protein -2.45029
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -2.43042
SRCIN1 SRC kinase signaling inhibitor 1 -2.42488
PEX3 peroxisomal biogenesis factor 3 -2.42319
GLIPR2 GLI pathogenesis-related 2 -2.38225
XKR4 XK, Kell blood group complex subunit-related family, member 4 -2.36445
SHISA9 shisa family member 9 -2.36445
RFC1 replication factor C (activator 1) 1, 145kDa -2.36081
STRAP serine/threonine kinase receptor associated protein -2.35221
CYB5R1 cytochrome b5 reductase 1 -2.34905
STMP1 short transmembrane mitochondrial protein 1 -2.30999
AUP1 ancient ubiquitous protein 1 -2.3086
RPS10 ribosomal protein S10 -2.30209
PRICKLE3 prickle homolog 3 (Drosophila) -2.29995
SMYD4 SET and MYND domain containing 4 -2.28113
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 -2.26764
TMEM234 transmembrane protein 234 -2.2625
AKAP5 A kinase (PRKA) anchor protein 5 -2.25395
RRAS related RAS viral (r-ras) oncogene homolog -2.24541
SCUBE1 signal peptide, CUB domain, EGF-like 1 -2.23765
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -2.23753
ADIPOR2 adiponectin receptor 2 -2.21152
SOD2 superoxide dismutase 2, mitochondrial -2.21152
TSNAXIP1 translin-associated factor X interacting protein 1 -2.2063
GSDMA gasdermin A -2.2063
WSCD1 WSC domain containing 1 -2.2063
SRRD SRR1 domain containing -2.20624
FHIP1A FHF complex subunit HOOK interacting protein 1A -2.19686
C2CD4C C2 calcium-dependent domain containing 4C -2.17997
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 -2.17709
NPHP4 nephronophthisis 4 -2.16897
ABI1 abl-interactor 1 -2.16375
NUP88 nucleoporin 88kDa -2.16375
MID1IP1 MID1 interacting protein 1 -2.1416
ATP9A ATPase, class II, type 9A -2.14137
DENND5B DENN/MADD domain containing 5B -2.12236
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 -2.10408
TMEM67 transmembrane protein 67 -2.10373
KCTD18 potassium channel tetramerization domain containing 18 -2.09495
PLPP1 phospholipid phosphatase 1 -2.07026
MTMR1 myotubularin related protein 1 -2.06077
CECR2 cat eye syndrome chromosome region, candidate 2 -2.04309
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled -2.03295
CCNJ cyclin J -2.03006
SERF2 small EDRK-rich factor 2 -2.02661
ANLN anillin, actin binding protein -2.02661
LRRC49 leucine rich repeat containing 49 -2.02311
BTBD6 BTB (POZ) domain containing 6 -2.02311
VAMP4 vesicle-associated membrane protein 4 -2.01924
ERI3 ERI1 exoribonuclease family member 3 -2.01924
CXADR coxsackie virus and adenovirus receptor -2.00968
CEP192 centrosomal protein 192kDa -2.00232
TMSB15A thymosin beta 15a -2.00118