MEIS3 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description Meis homeobox 3| (NCBI Entrez Gene Database, 56917)
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Genes

319 genes differentially expressed following the MEIS3 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
ICAM2 intercellular adhesion molecule 2 3.70747
RFPL3 ret finger protein-like 3 3.70747
LYZL6 lysozyme-like 6 3.70747
LIM2 lens intrinsic membrane protein 2, 19kDa 3.70747
UCN2 urocortin 2 3.70747
FOLR3 folate receptor 3 (gamma) 3.70747
FETUB fetuin B 3.70747
OR2J3 olfactory receptor, family 2, subfamily J, member 3 3.70747
PCDHGB3 protocadherin gamma subfamily B, 3 3.70747
CAPNS2 calpain, small subunit 2 3.70747
TXNDC2 thioredoxin domain containing 2 (spermatozoa) 3.70747
PI16 peptidase inhibitor 16 3.70747
UCN urocortin 3.70747
DNAJC5B DnaJ (Hsp40) homolog, subfamily C, member 5 beta 3.70747
SOX1 SRY (sex determining region Y)-box 1 3.70747
SLFN11 schlafen family member 11 3.70747
LAPTM5 lysosomal protein transmembrane 5 3.70747
SIX6 SIX homeobox 6 3.70747
POSTN periostin, osteoblast specific factor 3.70747
TPSD1 tryptase delta 1 3.70747
C3ORF22 chromosome 3 open reading frame 22 3.70747
OR6B1 olfactory receptor, family 6, subfamily B, member 1 3.70747
ANXA2R annexin A2 receptor 3.70747
FAM81B family with sequence similarity 81, member B 3.70747
PRSS22 protease, serine, 22 3.70747
PRR29 proline rich 29 3.70747
MAS1 MAS1 proto-oncogene, G protein-coupled receptor 3.70747
SPACA3 sperm acrosome associated 3 3.70747
CRYAA crystallin, alpha A 3.70747
RNF133 ring finger protein 133 3.70747
IL2RA interleukin 2 receptor, alpha 3.70747
BFSP2 beaded filament structural protein 2, phakinin 3.70747
MMP20 matrix metallopeptidase 20 3.70747
WNT8B wingless-type MMTV integration site family, member 8B 3.70747
TTLL8 tubulin tyrosine ligase-like family member 8 3.70747
SCPPPQ1 secretory calcium-binding phosphoprotein proline-glutamine rich 1 3.70747
TMEM71 transmembrane protein 71 3.70747
OR1L6 olfactory receptor, family 1, subfamily L, member 6 3.70747
SRPX2 sushi-repeat containing protein, X-linked 2 3.70747
WEE2 WEE1 homolog 2 (S. pombe) 3.70747
SLC22A10 solute carrier family 22, member 10 3.70747
OR2T8 olfactory receptor, family 2, subfamily T, member 8 3.70747
SPEM1 spermatid maturation 1 3.70747
GPX5 glutathione peroxidase 5 3.70747
ROPN1L rhophilin associated tail protein 1-like 3.70747
EIF2S3B eukaryotic translation initiation factor 2 subunit gamma B 3.70747
STING1 stimulator of interferon response cGAMP interactor 1 3.70747
TMEM271 transmembrane protein 271 3.70747
GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 3.70747
GK3 glycerol kinase 3 3.70747
ELOA2 elongin A2 3.70747
DUSP29 dual specificity phosphatase 29 3.70747
NFILZ NFIL3 like basic leucine zipper 3.70747
GARIN4 golgi associated RAB2 interactor family member 4 3.70747
TEX13D TEX13 family member D 3.70747
OR52P1 olfactory receptor family 52 subfamily P member 1 (gene/pseudogene) 3.70747
PRR20G proline rich 20G 3.70747
SPEGNB SPEG neighbor 3.70747
SRGN serglycin 3.70747
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8 3.70747
ZNF705D zinc finger protein 705D 3.70747
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 3.70747
KBTBD13 kelch repeat and BTB (POZ) domain containing 13 3.70747
HDC histidine decarboxylase 3.70747
PCDHA2 protocadherin alpha 2 3.70747
KLHL33 kelch-like family member 33 3.70747
CLDN9 claudin 9 3.70747
CLEC3A C-type lectin domain family 3, member A 3.70747
IL6 interleukin 6 3.70747
PRR18 proline rich 18 3.70747
MS4A13 membrane-spanning 4-domains, subfamily A, member 13 3.70747
C9 complement component 9 3.70747
PTH parathyroid hormone 3.70747
FGFBP2 fibroblast growth factor binding protein 2 3.70747
TMEM119 transmembrane protein 119 3.70747
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 3.70747
GATA6 GATA binding protein 6 3.70747
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 3.70747
LY6S lymphocyte antigen 6 family member S 3.70747
RAD9B RAD9 homolog B (S. pombe) 3.70747
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 3.70747
PCDHGA2 protocadherin gamma subfamily A, 2 3.70747
CDHR5 cadherin-related family member 5 3.70747
GLOD5 glyoxalase domain containing 5 3.70747
S100Z S100 calcium binding protein Z 3.70747
UBQLNL ubiquilin-like 3.70747
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 3.70747
CTAGE15 CTAGE family, member 15 3.70747
ZNF541 zinc finger protein 541 3.70747
ERICH4 glutamate-rich 4 3.70747
CNTF ciliary neurotrophic factor 3.70747
MR1 major histocompatibility complex, class I-related 3.70747
ZNF132 zinc finger protein 132 3.70747
MYF5 myogenic factor 5 3.70747
LRRC46 leucine rich repeat containing 46 3.70747
GAL3ST2 galactose-3-O-sulfotransferase 2 3.70747
TIPE2 TNF alpha induced protein 8 like 2 3.70747
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 3.70747
KLK15 kallikrein-related peptidase 15 3.70747
GOLGA8J golgin A8 family, member J 3.70747
NPY2R neuropeptide Y receptor Y2 3.70747
MEPE matrix extracellular phosphoglycoprotein 3.70747
POU4F1 POU class 4 homeobox 1 3.70747
NKX6-3 NK6 homeobox 3 3.70747
TRIM7 tripartite motif containing 7 3.70747
CD27 CD27 molecule 3.70747
ZIM2 zinc finger, imprinted 2 3.70747
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 3.70747
DMRT2 doublesex and mab-3 related transcription factor 2 3.70747
AICDA activation-induced cytidine deaminase 3.70747
CTXN3 cortexin 3 3.70747
C8G complement component 8, gamma polypeptide 3.70747
GPR61 G protein-coupled receptor 61 3.70747
ZFP92 ZFP92 zinc finger protein 3.70747
FBXO47 F-box protein 47 3.70747
PCDHGB5 protocadherin gamma subfamily B, 5 3.70747
CABP7 calcium binding protein 7 3.70747
PADI6 peptidyl arginine deiminase, type VI 3.70747
CSF3R colony stimulating factor 3 receptor (granulocyte) 3.70747
WDFY4 WDFY family member 4 3.70747
MMP12 matrix metallopeptidase 12 3.70747
SLITRK1 SLIT and NTRK-like family, member 1 3.70747
CHAT choline O-acetyltransferase 3.70747
CETP cholesteryl ester transfer protein, plasma 3.70747
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 3.70747
CIB4 calcium and integrin binding family member 4 3.70747
NNMT nicotinamide N-methyltransferase 3.70747
TEX35 testis expressed 35 3.70747
BPIFC BPI fold containing family C 3.70747
MAGEA12 melanoma antigen family A12 3.70747
ALLC allantoicase 3.70747
SLCO1C1 solute carrier organic anion transporter family, member 1C1 3.70747
PRSS57 protease, serine, 57 3.70747
OR3A1 olfactory receptor, family 3, subfamily A, member 1 3.70747
IFNK interferon, kappa 3.70747
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 3.70747
DYTN dystrotelin 3.70747
XAF1 XIAP associated factor 1 3.70747
NLGN4X neuroligin 4, X-linked 3.41814
OTUD7B OTU deubiquitinase 7B 3.11002
TMPRSS2 transmembrane protease, serine 2 2.76373
CADM3 cell adhesion molecule 3 2.73431
GOLGA3 golgin A3 2.63229
NLRP12 NLR family, pyrin domain containing 12 2.58799
KHDC4 KH domain containing 4, pre-mRNA splicing factor 2.58749
PCDH7 protocadherin 7 2.58364
C10ORF90 chromosome 10 open reading frame 90 2.56183
AZGP1 alpha-2-glycoprotein 1, zinc-binding 2.56183
LCN12 lipocalin 12 2.56183
VSTM2A V-set and transmembrane domain containing 2A 2.56183
DUSP8 dual specificity phosphatase 8 2.56183
KDM7A lysine (K)-specific demethylase 7A 2.51401
ZNF789 zinc finger protein 789 2.51365
PRPS2 phosphoribosyl pyrophosphate synthetase 2 2.50071
CREB3L4 cAMP responsive element binding protein 3-like 4 2.46305
RCL1 RNA terminal phosphate cyclase-like 1 2.46197
CBR4 carbonyl reductase 4 2.45132
WFDC2 WAP four-disulfide core domain 2 2.44581
ARHGAP4 Rho GTPase activating protein 4 2.43829
KANSL3 KAT8 regulatory NSL complex subunit 3 2.40823
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 2.40058
CALN1 calneuron 1 2.38404
MCTS1 malignant T cell amplified sequence 1 2.35504
HDX highly divergent homeobox 2.33855
RNF157 ring finger protein 157 2.32684
ZNF681 zinc finger protein 681 2.31367
COX14 COX14 cytochrome c oxidase assembly factor 2.31308
SEPTIN1 septin 1 2.29615
FAM110A family with sequence similarity 110, member A 2.28475
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 2.27367
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12) 2.26677
AGO1 argonaute RISC catalytic component 1 2.2429
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 2.23501
CHRND cholinergic receptor, nicotinic, delta (muscle) 2.23349
HRH4 histamine receptor H4 2.23349
CAND2 cullin-associated and neddylation-dissociated 2 (putative) 2.22247
UBE2E3 ubiquitin-conjugating enzyme E2E 3 2.21356
NAMPT nicotinamide phosphoribosyltransferase 2.19524
GPR179 G protein-coupled receptor 179 2.18854
RNMT RNA (guanine-7-) methyltransferase 2.18374
LMO3 LIM domain only 3 (rhombotin-like 2) 2.18061
XTBD1 XRN2 binding domain containing 1 2.17515
NEK8 NIMA-related kinase 8 2.17217
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 2.16917
MSRA methionine sulfoxide reductase A 2.16342
H2AC4 H2A clustered histone 4 2.16342
PXDN peroxidasin 2.14542
UNC13B unc-13 homolog B (C. elegans) 2.14542
SDCCAG8 serologically defined colon cancer antigen 8 2.1426
USP47 ubiquitin specific peptidase 47 2.13089
HK1 hexokinase 1 2.13089
WDR7 WD repeat domain 7 2.12161
PCSK7 proprotein convertase subtilisin/kexin type 7 2.12161
CDNF cerebral dopamine neurotrophic factor 2.07635
PTPRD protein tyrosine phosphatase, receptor type, D 2.07635
INO80C INO80 complex subunit C 2.07635
NLRP2 NLR family, pyrin domain containing 2 2.07635
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 2.07635
GPX4 glutathione peroxidase 4 2.06857
FAM24B family with sequence similarity 24, member B 2.06549
TSSK6 testis-specific serine kinase 6 2.06088
ICA1 islet cell autoantigen 1, 69kDa 2.05522
ZNF805 zinc finger protein 805 2.05522
WDR6 WD repeat domain 6 2.04789
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 2.03367
ZNF580 zinc finger protein 580 2.0331
RNASEH1 ribonuclease H1 2.0312
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 2.0239

decreased expression

Symbol Name Standardized Value
ART1 ADP-ribosyltransferase 1 -3.70747
GJB1 gap junction protein, beta 1, 32kDa -3.70747
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 -3.70747
C22ORF42 chromosome 22 open reading frame 42 -3.70747
SWI5 SWI5 recombination repair homolog (yeast) -3.70747
SERINC4 serine incorporator 4 -3.70747
FSD2 fibronectin type III and SPRY domain containing 2 -3.70747
OLFML1 olfactomedin-like 1 -3.70747
C1ORF141 chromosome 1 open reading frame 141 -3.70747
LCN10 lipocalin 10 -3.70747
GALR3 galanin receptor 3 -3.70747
FGF7 fibroblast growth factor 7 -3.70747
SNAI2 snail family zinc finger 2 -3.70747
TGM6 transglutaminase 6 -3.70747
APOD apolipoprotein D -3.70747
KRT15 keratin 15, type I -3.70747
WAS Wiskott-Aldrich syndrome -3.70747
APLN apelin -3.70747
ECEL1 endothelin converting enzyme-like 1 -3.70747
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -3.70747
OR52N2 olfactory receptor, family 52, subfamily N, member 2 -3.70747
CHCT1 CHD1 helical C-terminal domain containing 1 -3.70747
GJC2 gap junction protein, gamma 2, 47kDa -3.70747
KRT86 keratin 86, type II -3.70747
ORM2 orosomucoid 2 -3.70747
CMKLR1 chemerin chemokine-like receptor 1 -3.70747
TMEM150B transmembrane protein 150B -3.70747
PFN4 profilin family, member 4 -3.70747
FLRT3 fibronectin leucine rich transmembrane protein 3 -3.70747
SEL1L2 sel-1 suppressor of lin-12-like 2 (C. elegans) -3.70747
ENTHD1 ENTH domain containing 1 -3.70747
TDRD10 tudor domain containing 10 -3.70747
SLC35G5 solute carrier family 35, member G5 -3.70747
RBM24 RNA binding motif protein 24 -3.70747
PCP4L1 Purkinje cell protein 4 like 1 -3.70747
RIPK4 receptor-interacting serine-threonine kinase 4 -3.36203
TTN titin -2.95526
TAFA4 TAFA chemokine like family member 4 -2.91824
COX17 COX17 cytochrome c oxidase copper chaperone -2.86902
DRP2 dystrophin related protein 2 -2.82671
RIBC1 RIB43A domain with coiled-coils 1 -2.82671
CYB561D1 cytochrome b561 family, member D1 -2.82661
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -2.80523
SLITRK3 SLIT and NTRK-like family, member 3 -2.80523
BTNL9 butyrophilin-like 9 -2.80523
CSMD3 CUB and Sushi multiple domains 3 -2.80523
CIITA class II, major histocompatibility complex, transactivator -2.80523
H3C14 H3 clustered histone 14 -2.80523
SCNN1D sodium channel, non voltage gated 1 delta subunit -2.80523
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3 -2.78749
SIRT3 sirtuin 3 -2.76238
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 -2.74845
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 -2.58564
RASGEF1A RasGEF domain family, member 1A -2.58364
OGA O-GlcNAcase -2.56183
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 -2.50575
LOC124904942 uncharacterized LOC124904942 -2.50207
SAMHD1 SAM domain and HD domain 1 -2.4725
FRS3 fibroblast growth factor receptor substrate 3 -2.46197
TUFM Tu translation elongation factor, mitochondrial -2.46197
ATF1 activating transcription factor 1 -2.45164
ASTN1 astrotactin 1 -2.45119
TFR2 transferrin receptor 2 -2.44449
TIMP4 TIMP metallopeptidase inhibitor 4 -2.43531
DNAL1 dynein, axonemal, light chain 1 -2.43531
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -2.40052
FPGS folylpolyglutamate synthase -2.39746
ACKR3 atypical chemokine receptor 3 -2.37694
CARMIL3 capping protein regulator and myosin 1 linker 3 -2.37266
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 -2.35686
ZNF823 zinc finger protein 823 -2.35686
ALKBH5 AlkB family member 5, RNA demethylase -2.35662
PTPDC1 protein tyrosine phosphatase domain containing 1 -2.35407
RGPD6 RANBP2-like and GRIP domain containing 6 -2.35407
TMEM184A transmembrane protein 184A -2.35273
GLRB glycine receptor, beta -2.31367
CAMK1D calcium/calmodulin-dependent protein kinase ID -2.28586
ZNF682 zinc finger protein 682 -2.28475
RNASEH2A ribonuclease H2, subunit A -2.28321
PKP3 plakophilin 3 -2.27779
LMNTD1 lamin tail domain containing 1 -2.26882
CYS1 cystin 1 -2.26882
DEFB131B defensin beta 131B -2.26882
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) -2.2472
CST6 cystatin E/M -2.23501
ZNF671 zinc finger protein 671 -2.21356
PWWP3B PWWP domain containing 3B -2.19178
RGS2 regulator of G-protein signaling 2 -2.18991
EIF3E eukaryotic translation initiation factor 3, subunit E -2.18854
IL2RB interleukin 2 receptor, beta -2.18061
NKX3-1 NK3 homeobox 1 -2.18061
TROAP trophinin associated protein -2.17714
CR1L complement component (3b/4b) receptor 1-like -2.17217
CENPV centromere protein V -2.16716
TBC1D20 TBC1 domain family, member 20 -2.12033
HK2 hexokinase 2 -2.12004
CD163L1 CD163 molecule-like 1 -2.10651
SEC31B SEC31 homolog B (S. cerevisiae) -2.10282
CTF1 cardiotrophin 1 -2.07635
ZBTB44 zinc finger and BTB domain containing 44 -2.07635
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G -2.06692
UNKL unkempt family zinc finger-like -2.06692
ZNF546 zinc finger protein 546 -2.06088
PPP1R10 protein phosphatase 1, regulatory subunit 10 -2.06088
PTMA prothymosin, alpha -2.05522
MPDU1 mannose-P-dolichol utilization defect 1 -2.05522
SYP synaptophysin -2.03868
PLD2 phospholipase D2 -2.0327
DPP7 dipeptidyl-peptidase 7 -2.02928
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 -2.01055
CER1 cerberus 1, DAN family BMP antagonist -2.00356