MEKK6 Gene Set

Dataset Kinase Library Serine Threonine Kinome Atlas
Category proteomics
Type kinase
Description mitogen-activated protein kinase kinase kinase 6|This gene encodes a serine/threonine protein kinase that forms a component of protein kinase-mediated signal transduction cascades. The encoded kinase participates in the regulation of vascular endothelial growth factor (VEGF) expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] (NCBI Entrez Gene Database, 9064)
Similar Terms
Downloads & Tools

Genes

100 substrates of the kinase MEKK6 from the Kinase Library Serine Threonine Kinome Atlas dataset.

Symbol Name Standardized Value
CD36 CD36 molecule (thrombospondin receptor)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
REPS1 RALBP1 associated Eps domain containing 1
LIX1L Lix1 homolog (chicken) like
RRAS related RAS viral (r-ras) oncogene homolog
MYBPC2 myosin binding protein C, fast type
MAP7D3 MAP7 domain containing 3
DCBLD2 discoidin, CUB and LCCL domain containing 2
EPS8L2 EPS8-like 2
EGFR epidermal growth factor receptor
RNF219 ring finger protein 219
HIST2H3D histone cluster 2, H3d
TRPV6 transient receptor potential cation channel, subfamily V, member 6
IRS1 insulin receptor substrate 1
TP53 tumor protein p53
UBASH3B ubiquitin associated and SH3 domain containing B
MYL9 myosin, light chain 9, regulatory
STK38 serine/threonine kinase 38
GMPR2 guanosine monophosphate reductase 2
STX4 syntaxin 4
CSNK1D casein kinase 1, delta
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8
STK3 serine/threonine kinase 3
IRS4 insulin receptor substrate 4
AKT1S1 AKT1 substrate 1 (proline-rich)
GCLM glutamate-cysteine ligase, modifier subunit
MTSS1 metastasis suppressor 1
WDR62 WD repeat domain 62
USP47 ubiquitin specific peptidase 47
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
CREBBP CREB binding protein
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYH1 myosin, heavy chain 1, skeletal muscle, adult
PARVB parvin, beta
PARVA parvin, alpha
GIPC1 GIPC PDZ domain containing family, member 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
MYH13 myosin, heavy chain 13, skeletal muscle
SNRK SNF related kinase
CD5 CD5 molecule
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
ERBB2 erb-b2 receptor tyrosine kinase 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
ERBB4 erb-b2 receptor tyrosine kinase 4
PTTG1 pituitary tumor-transforming 1
TUBA3E tubulin, alpha 3e
TUBA3D tubulin, alpha 3d
ILK integrin-linked kinase
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
LPAR1 lysophosphatidic acid receptor 1
YBX3 Y box binding protein 3
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
CXADR coxsackie virus and adenovirus receptor
INF2 inverted formin, FH2 and WH2 domain containing
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
SGK223 homolog of rat pragma of Rnd2
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
BAIAP2L1 BAI1-associated protein 2-like 1
HNRNPF heterogeneous nuclear ribonucleoprotein F
PINK1 PTEN induced putative kinase 1
HIST1H1C histone cluster 1, H1c
CYTH2 cytohesin 2
TUBA1A tubulin, alpha 1a
FHOD1 formin homology 2 domain containing 1
ILF3 interleukin enhancer binding factor 3, 90kDa
ADAM10 ADAM metallopeptidase domain 10
ADCY2 adenylate cyclase 2 (brain)
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
ABLIM1 actin binding LIM protein 1
SLK STE20-like kinase
TPD52L2 tumor protein D52-like 2
TUBA1C tubulin, alpha 1c
TUBA1B tubulin, alpha 1b
STK38L serine/threonine kinase 38 like
CNOT12 CCR4-NOT transcription complex subunit 12
JUP junction plakoglobin
CTNND1 catenin (cadherin-associated protein), delta 1
PUM1 pumilio RNA-binding family member 1
HIST3H3 histone cluster 3, H3
RCC2 regulator of chromosome condensation 2
NUP133 nucleoporin 133kDa
CASR calcium-sensing receptor
BRAF B-Raf proto-oncogene, serine/threonine kinase
FOXG1 forkhead box G1
FAM207A family with sequence similarity 207, member A
BLVRA biliverdin reductase A
HIST1H3F histone cluster 1, H3f
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
DAPK3 death-associated protein kinase 3
KIAA1549L KIAA1549-like
MAP3K11 mitogen-activated protein kinase kinase kinase 11
SYNM synemin, intermediate filament protein
NOP2 NOP2 nucleolar protein
CDR2L cerebellar degeneration-related protein 2-like
H3F3B H3 histone, family 3B (H3.3B)
MYOD1 myogenic differentiation 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
HSPB8 heat shock 22kDa protein 8
NOLC1 nucleolar and coiled-body phosphoprotein 1