MELK Gene Set

Dataset Kinase Library Serine Threonine Kinome Atlas
Category proteomics
Type kinase
Description maternal embryonic leucine zipper kinase| (NCBI Entrez Gene Database, 9833)
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Genes

100 substrates of the kinase MELK from the Kinase Library Serine Threonine Kinome Atlas dataset.

Symbol Name Standardized Value
SENP7 SUMO1/sentrin specific peptidase 7
ZBTB44 zinc finger and BTB domain containing 44
CASP9 caspase 9, apoptosis-related cysteine peptidase
RUNDC3A RUN domain containing 3A
MAP7D1 MAP7 domain containing 1
ZDHHC5 zinc finger, DHHC-type containing 5
ZNF462 zinc finger protein 462
RAB18 RAB18, member RAS oncogene family
LYST lysosomal trafficking regulator
TP53RK TP53 regulating kinase
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase
CABLES2 Cdk5 and Abl enzyme substrate 2
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
PDE3B phosphodiesterase 3B, cGMP-inhibited
PRDM2 PR domain containing 2, with ZNF domain
TBC1D4 TBC1 domain family, member 4
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
UBE2O ubiquitin-conjugating enzyme E2O
KIF23 kinesin family member 23
ISCU iron-sulfur cluster assembly enzyme
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
SH3RF1 SH3 domain containing ring finger 1
TRA2A transformer 2 alpha homolog (Drosophila)
PPP1R8 protein phosphatase 1, regulatory subunit 8
TRIM17 tripartite motif containing 17
TOR4A torsin family 4, member A
PBRM1 polybromo 1
SLC18B1 solute carrier family 18, subfamily B, member 1
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
PELI1 pellino E3 ubiquitin protein ligase 1
DUSP9 dual specificity phosphatase 9
DUSP7 dual specificity phosphatase 7
NADK NAD kinase
CEP170B centrosomal protein 170B
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
TKFC triokinase/FMN cyclase
ARHGAP19 Rho GTPase activating protein 19
SEPN1 selenoprotein N, 1
TCF20 transcription factor 20 (AR1)
TERF2IP telomeric repeat binding factor 2, interacting protein
NFE2L2 nuclear factor, erythroid 2-like 2
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
SRSF2 serine/arginine-rich splicing factor 2
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
TMEM9B TMEM9 domain family, member B
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
MAPKAP1 mitogen-activated protein kinase associated protein 1
NAV1 neuron navigator 1
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha
PRKD3 protein kinase D3
RARA retinoic acid receptor, alpha
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
RGS18 regulator of G-protein signaling 18
ZC3H13 zinc finger CCCH-type containing 13
NOP2 NOP2 nucleolar protein
APC adenomatous polyposis coli
SRRM2 serine/arginine repetitive matrix 2
ARHGAP22 Rho GTPase activating protein 22
PRKD2 protein kinase D2
PRKD1 protein kinase D1
RIMS3 regulating synaptic membrane exocytosis 3
RIN2 Ras and Rab interactor 2
C7ORF43 chromosome 7 open reading frame 43
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
PYGO2 pygopus family PHD finger 2
CDCA2 cell division cycle associated 2
BMPER BMP binding endothelial regulator
CHERP calcium homeostasis endoplasmic reticulum protein
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
PFKM phosphofructokinase, muscle
PRM2 protamine 2
RAP1B RAP1B, member of RAS oncogene family
RAP1A RAP1A, member of RAS oncogene family
PPP1R12A protein phosphatase 1, regulatory subunit 12A
GPR174 G protein-coupled receptor 174
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
SUCO SUN domain containing ossification factor
GRM7 glutamate receptor, metabotropic 7
TWIST1 twist family bHLH transcription factor 1
SETD2 SET domain containing 2
DGKZ diacylglycerol kinase, zeta
SSH3 slingshot protein phosphatase 3
CDC27 cell division cycle 27
PPP1R3G protein phosphatase 1, regulatory subunit 3G
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
MORC3 MORC family CW-type zinc finger 3
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
CCDC88B coiled-coil domain containing 88B
PRAM1 PML-RARA regulated adaptor molecule 1
INCENP inner centromere protein antigens 135/155kDa
SF1 splicing factor 1
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
NCAPH non-SMC condensin I complex, subunit H
TRPM2 transient receptor potential cation channel, subfamily M, member 2
NET1 neuroepithelial cell transforming 1