MEOX1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description mesenchyme homeobox 1|This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the molecular signaling network regulating somite development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4222)
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Genes

351 genes differentially expressed following the MEOX1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
OASL 2'-5'-oligoadenylate synthetase-like 2.91549
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 2.91549
UNC13C unc-13 homolog C (C. elegans) 2.91549
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 2.91549
MLANA melan-A 2.91549
IL1A interleukin 1, alpha 2.91549
EPN3 epsin 3 2.91549
PF4V1 platelet factor 4 variant 1 2.91549
ALLC allantoicase 2.91549
CD8B CD8b molecule 2.91549
CLEC4D C-type lectin domain family 4, member D 2.91549
SPATA3 spermatogenesis associated 3 2.91549
SCIMP SLP adaptor and CSK interacting membrane protein 2.91549
NDRG1 N-myc downstream regulated 1 2.91549
MSX1 msh homeobox 1 2.91549
CD160 CD160 molecule 2.91549
PRSS55 protease, serine, 55 2.91549
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 2.91549
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.91549
OR52N5 olfactory receptor, family 52, subfamily N, member 5 2.91549
SPMIP9 sperm microtubule inner protein 9 2.91549
CTSS cathepsin S 2.91549
TERB1 telomere repeat binding bouquet formation protein 1 2.91549
PKDCC protein kinase domain containing, cytoplasmic 2.91549
HES7 hes family bHLH transcription factor 7 2.80627
TREML1 triggering receptor expressed on myeloid cells-like 1 2.80627
EPPIN epididymal peptidase inhibitor 2.80627
GLUD2 glutamate dehydrogenase 2 2.80627
VSX1 visual system homeobox 1 2.80627
BANF2 barrier to autointegration factor 2 2.80627
MGAM2 maltase-glucoamylase 2 (putative) 2.80627
SLC39A12 solute carrier family 39 (zinc transporter), member 12 2.80627
TRIM15 tripartite motif containing 15 2.80627
CFHR3 complement factor H-related 3 2.80627
LAPTM5 lysosomal protein transmembrane 5 2.80627
CAMK4 calcium/calmodulin-dependent protein kinase IV 2.80627
INHBC inhibin, beta C 2.80627
OR1I1 olfactory receptor, family 1, subfamily I, member 1 2.80627
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 2.80627
MYO16 myosin XVI 2.80627
UCN urocortin 2.80627
IL5RA interleukin 5 receptor, alpha 2.80627
LRRIQ4 leucine-rich repeats and IQ motif containing 4 2.80627
LRRC10B leucine rich repeat containing 10B 2.80627
GNAT3 guanine nucleotide binding protein, alpha transducing 3 2.80627
XCL1 chemokine (C motif) ligand 1 2.80627
SLC39A5 solute carrier family 39 (zinc transporter), member 5 2.80627
BIRC3 baculoviral IAP repeat containing 3 2.80627
AVPR2 arginine vasopressin receptor 2 2.80627
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 2.80627
BSX brain-specific homeobox 2.80627
TMEM217 transmembrane protein 217 2.80627
UMODL1 uromodulin-like 1 2.80627
CRX cone-rod homeobox 2.80627
CLEC19A C-type lectin domain family 19, member A 2.80627
PTH2 parathyroid hormone 2 2.80627
OR10A6 olfactory receptor, family 10, subfamily A, member 6 (gene/pseudogene) 2.80627
COPZ2 coatomer protein complex, subunit zeta 2 2.80627
GJB5 gap junction protein, beta 5, 31.1kDa 2.80627
HBA1 hemoglobin, alpha 1 2.80627
SHE Src homology 2 domain containing E 2.80627
LACTBL1 lactamase, beta-like 1 2.80627
C3ORF22 chromosome 3 open reading frame 22 2.80627
SPMAP2L sperm microtubule associated protein 2 like 2.80627
GPR35 G protein-coupled receptor 35 2.80627
FMO3 flavin containing monooxygenase 3 2.80627
C9ORF43 chromosome 9 open reading frame 43 2.80627
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 2.80627
C20ORF202 chromosome 20 open reading frame 202 2.80627
TMPRSS4 transmembrane protease, serine 4 2.80627
PROX2 prospero homeobox 2 2.80627
IMPG2 interphotoreceptor matrix proteoglycan 2 2.80627
ZNF705B zinc finger protein 705B 2.80627
MRPS30 mitochondrial ribosomal protein S30 2.80627
PROP1 PROP paired-like homeobox 1 2.80627
ROPN1L rhophilin associated tail protein 1-like 2.80627
YPEL4 yippee-like 4 (Drosophila) 2.80627
TEX53 testis expressed 53 2.80627
PRRT1B proline rich transmembrane protein 1B 2.80627
H4C12 H4 clustered histone 12 2.80627
ODAPH odontogenesis associated phosphoprotein 2.80627
PLAAT2 phospholipase A and acyltransferase 2 2.80627
CYBC1 cytochrome b-245 chaperone 1 2.80627
ODAD1 outer dynein arm docking complex subunit 1 2.80627
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2 2.80627
PTH1R parathyroid hormone 1 receptor 2.80627
RPL10L ribosomal protein L10-like 2.80627
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5 2.80627
LRRN4CL LRRN4 C-terminal like 2.80627
PTP4A1 protein tyrosine phosphatase type IVA, member 1 2.80627
CKM creatine kinase, muscle 2.80627
CD48 CD48 molecule 2.80627
HPR haptoglobin-related protein 2.80627
CCR6 chemokine (C-C motif) receptor 6 2.80627
PCDHB11 protocadherin beta 11 2.80627
PRB2 proline-rich protein BstNI subfamily 2 2.80627
PCDHA7 protocadherin alpha 7 2.80627
ELAVL4 ELAV like neuron-specific RNA binding protein 4 2.80627
FPR2 formyl peptide receptor 2 2.80627
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 2.80627
OR2A12 olfactory receptor, family 2, subfamily A, member 12 2.80627
IL5 interleukin 5 2.80627
GDF6 growth differentiation factor 6 2.80627
DDTL D-dopachrome tautomerase-like 2.80627
SAMD15 sterile alpha motif domain containing 15 2.80627
OOSP2 oocyte secreted protein 2 2.80627
IL1RN interleukin 1 receptor antagonist 2.80627
C7 complement component 7 2.80627
PGLYRP1 peptidoglycan recognition protein 1 2.80627
NR0B1 nuclear receptor subfamily 0, group B, member 1 2.80627
RUNX3 runt-related transcription factor 3 2.80627
TPTE transmembrane phosphatase with tensin homology 2.80627
KBTBD13 kelch repeat and BTB (POZ) domain containing 13 2.80627
ERICH6B glutamate-rich 6B 2.80627
AQP7 aquaporin 7 2.80627
CRYBB2 crystallin, beta B2 2.80627
ANKRD63 ankyrin repeat domain 63 2.80627
LCN1 lipocalin 1 2.80627
RNASE11 ribonuclease, RNase A family, 11 (non-active) 2.80627
HPX hemopexin 2.80627
TRADD TNFRSF1A-associated via death domain 2.80627
CDH19 cadherin 19, type 2 2.80627
CLEC4M C-type lectin domain family 4, member M 2.80627
C11ORF96 chromosome 11 open reading frame 96 2.80627
CLDN34 claudin 34 2.80627
ZMYND15 zinc finger, MYND-type containing 15 2.80627
CIDEA cell death-inducing DFFA-like effector a 2.80627
PMP2 peripheral myelin protein 2 2.80627
PCDHGB1 protocadherin gamma subfamily B, 1 2.80627
CCDC154 coiled-coil domain containing 154 2.80627
BRDT bromodomain, testis-specific 2.80627
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1 2.80627
OPRK1 opioid receptor, kappa 1 2.80627
RGSL1 regulator of G-protein signaling like 1 2.80627
CYS1 cystin 1 2.80627
POU2AF1 POU class 2 associating factor 1 2.80627
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 2.80627
LY6G6D lymphocyte antigen 6 complex, locus G6D 2.80627
RIPK3 receptor-interacting serine-threonine kinase 3 2.80627
GPR142 G protein-coupled receptor 142 2.80627
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.80627
FAM151A family with sequence similarity 151, member A 2.80627
MEPE matrix extracellular phosphoglycoprotein 2.80627
OR52N2 olfactory receptor, family 52, subfamily N, member 2 2.80627
OR52N4 olfactory receptor, family 52, subfamily N, member 4 (gene/pseudogene) 2.80627
SLC36A3 solute carrier family 36, member 3 2.80627
ADGRD1 adhesion G protein-coupled receptor D1 2.80627
OTOP1 otopetrin 1 2.80627
UXS1 UDP-glucuronate decarboxylase 1 2.80627
KLK3 kallikrein-related peptidase 3 2.80627
KLK2 kallikrein-related peptidase 2 2.80627
LRRC15 leucine rich repeat containing 15 2.80627
ARL13A ADP-ribosylation factor-like 13A 2.80627
PI3 peptidase inhibitor 3, skin-derived 2.80627
CLEC9A C-type lectin domain family 9, member A 2.80627
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 2.80627
PRH2 proline-rich protein HaeIII subfamily 2 2.80627
ITGA8 integrin, alpha 8 2.80627
ASCL2 achaete-scute family bHLH transcription factor 2 2.80627
R3HDML R3H domain containing-like 2.80627
ZC3H11B zinc finger CCCH-type containing 11B pseudogene 2.80627
RNF220 ring finger protein 220 2.80627
FLG2 filaggrin family member 2 2.80627
CHI3L2 chitinase 3-like 2 2.80627
SYTL4 synaptotagmin-like 4 2.80627
TEX35 testis expressed 35 2.80627
NEUROD2 neuronal differentiation 2 2.80627
NLRP9 NLR family, pyrin domain containing 9 2.80627
LHB luteinizing hormone beta polypeptide 2.80627
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 2.80627
RAB7B RAB7B, member RAS oncogene family 2.80627
MYOZ2 myozenin 2 2.80627
ASCL5 achaete-scute family bHLH transcription factor 5 2.80627
CHRM1 cholinergic receptor, muscarinic 1 2.80627
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.80627
NMUR2 neuromedin U receptor 2 2.80627
RXRG retinoid X receptor, gamma 2.80627
TMEM132C transmembrane protein 132C 2.80627
TBC1D26 TBC1 domain family, member 26 2.80627
C9ORF50 chromosome 9 open reading frame 50 2.80627
LHX6 LIM homeobox 6 2.80627
CCDC87 coiled-coil domain containing 87 2.80627
NPR3 natriuretic peptide receptor 3 2.80627
SMCO3 single-pass membrane protein with coiled-coil domains 3 2.80627
DHRS9 dehydrogenase/reductase (SDR family) member 9 2.80627
CCDC159 coiled-coil domain containing 159 2.77752
MIEN1 migration and invasion enhancer 1 2.75238
FLT3LG fms-related tyrosine kinase 3 ligand 2.66544
TRPC6 transient receptor potential cation channel, subfamily C, member 6 2.66544
CASR calcium-sensing receptor 2.66544
PURA purine-rich element binding protein A 2.63222
SLC35G2 solute carrier family 35, member G2 2.55638
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 2.5336
RBSN rabenosyn, RAB effector 2.5308
CRK v-crk avian sarcoma virus CT10 oncogene homolog 2.49229
CNPY3 canopy FGF signaling regulator 3 2.49229
LRRD1 leucine-rich repeats and death domain containing 1 2.49229
TCEA2 transcription elongation factor A (SII), 2 2.48982
NUP155 nucleoporin 155kDa 2.44371
COPS6 COP9 signalosome subunit 6 2.43269
PHYH phytanoyl-CoA 2-hydroxylase 2.43269
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 2.42224
FBXO7 F-box protein 7 2.42224
MRPL3 mitochondrial ribosomal protein L3 2.38556
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.37852
DRC2 dynein regulatory complex subunit 2 2.33012
CXCR4 chemokine (C-X-C motif) receptor 4 2.31805
TMEM74B transmembrane protein 74B 2.28958
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 2.28958
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 2.2765
ABHD1 abhydrolase domain containing 1 2.2765
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 2.27643
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 2.26559
BCAP31 B-cell receptor-associated protein 31 2.2566
FAM20A family with sequence similarity 20, member A 2.24971
APCDD1 adenomatosis polyposis coli down-regulated 1 2.23857
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 2.23741
TMEM59L transmembrane protein 59-like 2.23233
ZSCAN22 zinc finger and SCAN domain containing 22 2.21311
NUTF2 nuclear transport factor 2 2.20785
KEAP1 kelch-like ECH-associated protein 1 2.20682
CDCA7L cell division cycle associated 7-like 2.17692
PPP1R9B protein phosphatase 1, regulatory subunit 9B 2.16848
ZNF112 zinc finger protein 112 2.15486
POM121L2 POM121 transmembrane nucleoporin-like 2 2.14143
FRMD8 FERM domain containing 8 2.13097
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.12841
ZNF573 zinc finger protein 573 2.10109
LRP12 low density lipoprotein receptor-related protein 12 2.08823
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 2.08612
AGAP5 ArfGAP with GTPase domain, ankyrin repeat and PH domain 5 2.08226
DSC3 desmocollin 3 2.08226
PRXL2B peroxiredoxin like 2B 2.04621
EPRS1 glutamyl-prolyl-tRNA synthetase 1 2.03214
NECAP2 NECAP endocytosis associated 2 2.02104
SYNE1 spectrin repeat containing, nuclear envelope 1 2.02104
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 2.02069
SYT10 synaptotagmin X 2.00296

decreased expression

Symbol Name Standardized Value
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 -2.91549
B3GALT6 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 -2.91549
GJA4 gap junction protein, alpha 4, 37kDa -2.91549
DND1 DND microRNA-mediated repression inhibitor 1 -2.91549
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 -2.91549
NBPF14 neuroblastoma breakpoint family, member 14 -2.91549
SPDYE17 speedy/RINGO cell cycle regulator family member E17 -2.91549
HMGN4 high mobility group nucleosomal binding domain 4 -2.91549
PCDHGA11 protocadherin gamma subfamily A, 11 -2.80627
OXER1 oxoeicosanoid (OXE) receptor 1 -2.80627
LOC124900192 uncharacterized LOC124900192 -2.80627
MAGED4 melanoma antigen family D4 -2.80627
B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 -2.80627
RMI1 RecQ mediated genome instability 1 -2.80627
NLRP6 NLR family, pyrin domain containing 6 -2.80627
NRGN neurogranin (protein kinase C substrate, RC3) -2.80627
CPLX1 complexin 1 -2.80627
TOMM20L translocase of outer mitochondrial membrane 20 homolog (yeast)-like -2.80627
GGTA1 glycoprotein alpha-galactosyltransferase 1 (inactive) -2.80627
PABPC1L2A poly(A) binding protein, cytoplasmic 1-like 2A -2.80627
VCX3B variable charge, X-linked 3B -2.80627
FAM186A family with sequence similarity 186, member A -2.80627
PCBP1 poly(rC) binding protein 1 -2.80627
ZNF98 zinc finger protein 98 -2.80627
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha -2.80627
AKAP6 A kinase (PRKA) anchor protein 6 -2.80627
CD1C CD1c molecule -2.80627
PLXDC1 plexin domain containing 1 -2.80627
RTL5 retrotransposon Gag like 5 -2.80627
PCDHGB2 protocadherin gamma subfamily B, 2 -2.80627
ARR3 arrestin 3, retinal (X-arrestin) -2.80627
PRH1 proline-rich protein HaeIII subfamily 1 -2.80627
PTCH2 patched 2 -2.80627
PIH1D2 PIH1 domain containing 2 -2.80627
EFCC1 EF-hand and coiled-coil domain containing 1 -2.80627
RAD51AP2 RAD51 associated protein 2 -2.80627
DAW1 dynein assembly factor with WDR repeat domains 1 -2.80627
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) -2.80627
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) -2.80627
DGCR6 DiGeorge syndrome critical region gene 6 -2.80627
SPATA45 spermatogenesis associated 45 -2.80627
C11ORF16 chromosome 11 open reading frame 16 -2.80627
PTPN20 protein tyrosine phosphatase, non-receptor type 20 -2.80627
GSTM4 glutathione S-transferase mu 4 -2.80419
SPTBN5 spectrin, beta, non-erythrocytic 5 -2.7631
TXLNB taxilin beta -2.7631
TADA1 transcriptional adaptor 1 -2.72612
CKS1B CDC28 protein kinase regulatory subunit 1B -2.63222
PNPLA7 patatin-like phospholipase domain containing 7 -2.5308
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C -2.52958
IL1RAPL2 interleukin 1 receptor accessory protein-like 2 -2.51016
EGLN3 egl-9 family hypoxia-inducible factor 3 -2.50591
USP6 ubiquitin specific peptidase 6 -2.4968
ASTN2 astrotactin 2 -2.49229
SYNGAP1 synaptic Ras GTPase activating protein 1 -2.49229
IFT20 intraflagellar transport 20 -2.48619
TRMT10B tRNA methyltransferase 10 homolog B (S. cerevisiae) -2.48619
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) -2.48619
ENTREP1 endosomal transmembrane epsin interactor 1 -2.48619
ISOC1 isochorismatase domain containing 1 -2.40029
NPIPB11 nuclear pore complex interacting protein family, member B11 -2.39681
ZNF750 zinc finger protein 750 -2.39681
LOX lysyl oxidase -2.39681
LRRC4C leucine rich repeat containing 4C -2.39271
POLR2M polymerase (RNA) II (DNA directed) polypeptide M -2.36418
MED13L mediator complex subunit 13-like -2.36341
SURF2 surfeit 2 -2.32641
TMEM17 transmembrane protein 17 -2.27861
SELENOP selenoprotein P -2.2765
FTCDNL1 formiminotransferase cyclodeaminase N-terminal like -2.26321
TSNAXIP1 translin-associated factor X interacting protein 1 -2.25678
POPDC3 popeye domain containing 3 -2.25288
PHACTR1 phosphatase and actin regulator 1 -2.25096
IRAG1 inositol 1,4,5-triphosphate receptor associated 1 -2.24971
KNSTRN kinetochore-localized astrin/SPAG5 binding protein -2.23857
PPIL6 peptidylprolyl isomerase (cyclophilin)-like 6 -2.23781
KLHL7 kelch-like family member 7 -2.23781
SMYD3 SET and MYND domain containing 3 -2.21218
NCR1 natural cytotoxicity triggering receptor 1 -2.20785
CFAP54 cilia and flagella associated 54 -2.20785
ZBTB1 zinc finger and BTB domain containing 1 -2.20042
NUP35 nucleoporin 35kDa -2.19999
ERBIN erbb2 interacting protein -2.18818
SLC22A23 solute carrier family 22, member 23 -2.17591
TTC33 tetratricopeptide repeat domain 33 -2.17389
ZBTB4 zinc finger and BTB domain containing 4 -2.1715
PXK PX domain containing serine/threonine kinase -2.16349
FBXO28 F-box protein 28 -2.15932
BCAM basal cell adhesion molecule (Lutheran blood group) -2.15902
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase -2.13234
ARC activity-regulated cytoskeleton-associated protein -2.12841
RGS14 regulator of G-protein signaling 14 -2.12773
PRKDC protein kinase, DNA-activated, catalytic polypeptide -2.12104
COA3 cytochrome c oxidase assembly factor 3 -2.11713
TIMP1 TIMP metallopeptidase inhibitor 1 -2.11662
REL v-rel avian reticuloendotheliosis viral oncogene homolog -2.10983
EIF3I eukaryotic translation initiation factor 3, subunit I -2.10482
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) -2.1037
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha -2.09578
TRIL TLR4 interactor with leucine-rich repeats -2.08793
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 -2.08793
PROKR2 prokineticin receptor 2 -2.08793
PLAC1 placenta-specific 1 -2.08793
PYDC1 PYD (pyrin domain) containing 1 -2.08793
FHL3 four and a half LIM domains 3 -2.08612
NPDC1 neural proliferation, differentiation and control, 1 -2.08612
TWNK twinkle mtDNA helicase -2.08612
DSC2 desmocollin 2 -2.07308
LRRC8D leucine rich repeat containing 8 family, member D -2.07308
FAM110A family with sequence similarity 110, member A -2.02492
TTC39A tetratricopeptide repeat domain 39A -2.02118
ZSCAN31 zinc finger and SCAN domain containing 31 -2.02104
DOK6 docking protein 6 -2.00308