MERO14 Gene Set

Dataset DepMap CRISPR Gene Dependency
Category disease or phenotype associations
Type cell line
Description Pleural Mesothelioma, Epithelioid Type cell line (Cancer Dependency Map)
External Link https://depmap.org/portal/cell_line/ACH-001555
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Genes

687 gene knockdowns changing fitness of MERO14 relative to other cell lines from the DepMap CRISPR Gene Dependency Dataset.

Symbol Name Standardized Value
XPC xeroderma pigmentosum, complementation group C 13.8783
GSN gelsolin 12.5231
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 12.1296
RIMS3 regulating synaptic membrane exocytosis 3 11.821
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 11.2142
PTPRR protein tyrosine phosphatase, receptor type, R 10.0691
IL17RE interleukin 17 receptor E 9.98699
CCDC24 coiled-coil domain containing 24 9.86355
C11ORF16 chromosome 11 open reading frame 16 9.77193
DCAF11 DDB1 and CUL4 associated factor 11 9.48832
RAB39A RAB39A, member RAS oncogene family 9.46353
PKNOX1 PBX/knotted 1 homeobox 1 9.38543
NPAS1 neuronal PAS domain protein 1 9.12908
TLX2 T-cell leukemia homeobox 2 9.10864
GCM2 glial cells missing homolog 2 (Drosophila) 8.89688
RNF144B ring finger protein 144B 8.71068
KBTBD13 kelch repeat and BTB (POZ) domain containing 13 8.70237
GC group-specific component (vitamin D binding protein) 8.61742
C5ORF22 chromosome 5 open reading frame 22 8.49402
USP11 ubiquitin specific peptidase 11 8.30227
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 8.26549
CPN2 carboxypeptidase N, polypeptide 2 8.18078
C1ORF226 chromosome 1 open reading frame 226 8.1449
HYLS1 hydrolethalus syndrome 1 7.92486
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 7.9078
FXYD1 FXYD domain containing ion transport regulator 1 7.75283
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 7.72729
OR2A5 olfactory receptor, family 2, subfamily A, member 5 7.72482
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 7.66694
VAT1L vesicle amine transport 1-like 7.58731
MUSK muscle, skeletal, receptor tyrosine kinase 7.2511
SLC4A11 solute carrier family 4, sodium borate transporter, member 11 7.07082
PAX2 paired box 2 7.0204
DENND11 DENN domain containing 11 6.98494
TPRX1 tetra-peptide repeat homeobox 1 6.98438
CCNJL cyclin J-like 6.92074
PRKD3 protein kinase D3 6.81295
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional) 6.78392
TTC26 tetratricopeptide repeat domain 26 6.77278
FGF21 fibroblast growth factor 21 6.75961
ZKSCAN7 zinc finger with KRAB and SCAN domains 7 6.732
EIF5A2 eukaryotic translation initiation factor 5A2 6.69702
TMUB2 transmembrane and ubiquitin-like domain containing 2 6.66476
DMRT2 doublesex and mab-3 related transcription factor 2 6.52152
CCDC37 coiled-coil domain containing 37 6.46689
WFDC3 WAP four-disulfide core domain 3 6.45148
STOX2 storkhead box 2 6.44954
ELOVL3 ELOVL fatty acid elongase 3 6.25842
MAPK11 mitogen-activated protein kinase 11 6.24277
SIGLEC12 sialic acid binding Ig-like lectin 12 (gene/pseudogene) 6.23144
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 6.21791
IQCC IQ motif containing C 6.17539
FOXD2 forkhead box D2 6.15375
VWA5A von Willebrand factor A domain containing 5A 6.12655
CXCR4 chemokine (C-X-C motif) receptor 4 6.10761
CLDND1 claudin domain containing 1 6.09738
PPARD peroxisome proliferator-activated receptor delta 6.06115
SAXO1 stabilizer of axonemal microtubules 1 6.02664
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 5.92326
OSBPL7 oxysterol binding protein-like 7 5.87063
IRF2 interferon regulatory factor 2 5.84781
CAPN2 calpain 2, (m/II) large subunit 5.84226
CDH12 cadherin 12, type 2 (N-cadherin 2) 5.83381
MREG melanoregulin 5.8245
ABLIM2 actin binding LIM protein family, member 2 5.78278
MORN4 MORN repeat containing 4 5.73994
C2CD4B C2 calcium-dependent domain containing 4B 5.73819
PRKCG protein kinase C, gamma 5.72697
ZNFX1 zinc finger, NFX1-type containing 1 5.59612
RIOX2 ribosomal oxygenase 2 5.58384
TMEM60 transmembrane protein 60 5.5803
ANKRD53 ankyrin repeat domain 53 5.55215
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 5.49753
C1ORF216 chromosome 1 open reading frame 216 5.48383
LMCD1 LIM and cysteine-rich domains 1 5.47787
TTC31 tetratricopeptide repeat domain 31 5.4007
ATP2A3 ATPase, Ca++ transporting, ubiquitous 5.38907
LOXHD1 lipoxygenase homology domains 1 5.37533
B3GALT6 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 5.34222
PSG3 pregnancy specific beta-1-glycoprotein 3 5.34183
CES2 carboxylesterase 2 5.27691
ZBED2 zinc finger, BED-type containing 2 5.26979
CD164L2 CD164 sialomucin-like 2 5.23046
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 5.20529
DNMBP dynamin binding protein 5.18609
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) 5.17767
ZNF362 zinc finger protein 362 5.17592
TAAR6 trace amine associated receptor 6 5.15357
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 5.15214
ATRAID all-trans retinoic acid-induced differentiation factor 5.15144
JOSD2 Josephin domain containing 2 5.13026
LYPD5 LY6/PLAUR domain containing 5 5.12946
FMNL1 formin-like 1 5.1262
ZNF232 zinc finger protein 232 5.12501
SPEF1 sperm flagellar 1 5.11372
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 5.11247
OR2B6 olfactory receptor, family 2, subfamily B, member 6 5.08258
OR2A12 olfactory receptor, family 2, subfamily A, member 12 5.0772
SLC26A11 solute carrier family 26 (anion exchanger), member 11 5.04006
CTH cystathionine gamma-lyase 4.92652
OMD osteomodulin 4.8943
NME8 NME/NM23 family member 8 4.8789
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 4.87034
KIAA1614 KIAA1614 4.85673
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 4.84189
ANKRD13D ankyrin repeat domain 13 family, member D 4.81244
NIM1K NIM1 serine/threonine protein kinase 4.81158
NPY2R neuropeptide Y receptor Y2 4.80845
SLC17A4 solute carrier family 17, member 4 4.74781
PNPLA2 patatin-like phospholipase domain containing 2 4.73929
ZNF836 zinc finger protein 836 4.73378
MRGPRX1 MAS-related GPR, member X1 4.71334
NECAB3 N-terminal EF-hand calcium binding protein 3 4.67526
KRT76 keratin 76, type II 4.66649
LMBR1 limb development membrane protein 1 4.62663
MUL1 mitochondrial E3 ubiquitin protein ligase 1 4.62061
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 4.61464
CCL19 chemokine (C-C motif) ligand 19 4.60941
GTF2H5 general transcription factor IIH, polypeptide 5 4.59865
HHIPL1 HHIP-like 1 4.59464
LCE2D late cornified envelope 2D 4.58828
SLC10A4 solute carrier family 10, member 4 4.58443
TAGLN transgelin 4.56382
SMAD3 SMAD family member 3 4.55926
IL20RB interleukin 20 receptor beta 4.53921
MYLK4 myosin light chain kinase family, member 4 4.53274
SCAMP3 secretory carrier membrane protein 3 4.53033
TRIO trio Rho guanine nucleotide exchange factor 4.52806
FAM198A family with sequence similarity 198, member A 4.52209
RBBP8NL RBBP8 N-terminal like 4.49414
PTTG1IP pituitary tumor-transforming 1 interacting protein 4.47135
MYLK2 myosin light chain kinase 2 4.46436
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 4.43731
TRNP1 TMF1-regulated nuclear protein 1 4.40847
DCC DCC netrin 1 receptor 4.39532
IFNLR1 interferon, lambda receptor 1 4.36355
NPHP1 nephronophthisis 1 (juvenile) 4.36195
MINK1 misshapen-like kinase 1 4.35616
RAD54L2 RAD54-like 2 (S. cerevisiae) 4.3465
BLCAP bladder cancer associated protein 4.34484
NEURL4 neuralized E3 ubiquitin protein ligase 4 4.34183
ALOXE3 arachidonate lipoxygenase 3 4.34061
THEM5 thioesterase superfamily member 5 4.33599
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 4.32096
CEP120 centrosomal protein 120kDa 4.31948
TSPYL1 TSPY-like 1 4.31682
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 4.31003
UBASH3B ubiquitin associated and SH3 domain containing B 4.30168
BBS9 Bardet-Biedl syndrome 9 4.30079
OR13J1 olfactory receptor, family 13, subfamily J, member 1 4.29424
MTFR1L mitochondrial fission regulator 1-like 4.28573
LHCGR luteinizing hormone/choriogonadotropin receptor 4.28053
FITM1 fat storage-inducing transmembrane protein 1 4.27524
CASKIN1 CASK interacting protein 1 4.27443
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 4.27008
INSM2 insulinoma-associated 2 4.26381
ZNF18 zinc finger protein 18 4.25475
CCRL2 chemokine (C-C motif) receptor-like 2 4.24557
TTC9C tetratricopeptide repeat domain 9C 4.23777
VSNL1 visinin-like 1 4.23448
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 4.21905
FAM181A family with sequence similarity 181, member A 4.20831
TMOD1 tropomodulin 1 4.19771
LRRC10 leucine rich repeat containing 10 4.1805
OR2A2 olfactory receptor, family 2, subfamily A, member 2 4.17055
ELN elastin 4.1583
ZNF337 zinc finger protein 337 4.14244
PDZD7 PDZ domain containing 7 4.12446
TMBIM4 transmembrane BAX inhibitor motif containing 4 4.12336
KLF8 Kruppel-like factor 8 4.11642
AIM2 absent in melanoma 2 4.11395
KLK6 kallikrein-related peptidase 6 4.11109
CMTM2 CKLF-like MARVEL transmembrane domain containing 2 4.0987
DCBLD2 discoidin, CUB and LCCL domain containing 2 4.08948
BSDC1 BSD domain containing 1 4.06545
PKD2L1 polycystic kidney disease 2-like 1 4.03724
BFSP2 beaded filament structural protein 2, phakinin 4.0249
KCNK2 potassium channel, two pore domain subfamily K, member 2 4.01269
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 4.00525
SOSTDC1 sclerostin domain containing 1 4.00384
ASL argininosuccinate lyase 3.99329
CFAP45 cilia and flagella associated protein 45 3.95438
ACCSL 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)-like 3.95052
C9ORF173 chromosome 9 open reading frame 173 3.94732
KLHDC3 kelch domain containing 3 3.94559
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 3.94514
VRK2 vaccinia related kinase 2 3.93934
KCTD8 potassium channel tetramerization domain containing 8 3.93294
SORCS2 sortilin-related VPS10 domain containing receptor 2 3.92777
NPM3 nucleophosmin/nucleoplasmin 3 3.91525
RAB29 RAB29, member RAS oncogene family 3.90852
ZNF483 zinc finger protein 483 3.90803
CCNI2 cyclin I family, member 2 3.89541
HMGXB3 HMG box domain containing 3 3.8931
ZNF436 zinc finger protein 436 3.87781
NR1H4 nuclear receptor subfamily 1, group H, member 4 3.87062
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 3.83503
COL8A1 collagen, type VIII, alpha 1 3.8271
STK32B serine/threonine kinase 32B 3.82291
CASP14 caspase 14, apoptosis-related cysteine peptidase 3.8217
TMEM144 transmembrane protein 144 3.81982
MYO7A myosin VIIA 3.8176
SPEG SPEG complex locus 3.81206
TMEM72 transmembrane protein 72 3.81085
GLRA1 glycine receptor, alpha 1 3.81007
APOA1 apolipoprotein A-I 3.80037
LALBA lactalbumin, alpha- 3.79872
NCMAP noncompact myelin associated protein 3.79201
C1ORF111 chromosome 1 open reading frame 111 3.79142
SAP25 Sin3A-associated protein, 25kDa 3.7902
TESK1 testis-specific kinase 1 3.78723
HID1 HID1 domain containing 3.78696
DOCK7 dedicator of cytokinesis 7 3.77255
PTPRN protein tyrosine phosphatase, receptor type, N 3.75928
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) 3.74139
USP16 ubiquitin specific peptidase 16 3.74101
C20ORF85 chromosome 20 open reading frame 85 3.72925
TMEM74 transmembrane protein 74 3.71392
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) 3.7133
ITGB8 integrin, beta 8 3.69963
CAPZA3 capping protein (actin filament) muscle Z-line, alpha 3 3.69906
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1 3.6931
ORAI2 ORAI calcium release-activated calcium modulator 2 3.68933
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 3.68818
TMEM253 transmembrane protein 253 3.68712
RAB12 RAB12, member RAS oncogene family 3.66279
RHPN2 rhophilin, Rho GTPase binding protein 2 3.6611
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 3.64395
FRS3 fibroblast growth factor receptor substrate 3 3.64085
BEND3 BEN domain containing 3 3.61571
POPDC3 popeye domain containing 3 3.61205
HSPA2 heat shock 70kDa protein 2 3.57905
FXYD3 FXYD domain containing ion transport regulator 3 3.57441
THTPA thiamine triphosphatase 3.57287
TMEM175 transmembrane protein 175 3.54786
FAM110D family with sequence similarity 110, member D 3.54405
MX1 MX dynamin-like GTPase 1 3.52832
CADM4 cell adhesion molecule 4 3.51729
GOT1 glutamic-oxaloacetic transaminase 1, soluble 3.51052
EDF1 endothelial differentiation-related factor 1 3.50341
CES4A carboxylesterase 4A 3.50339
GFPT2 glutamine-fructose-6-phosphate transaminase 2 3.49704
CAPRIN1 cell cycle associated protein 1 3.48987
P2RY1 purinergic receptor P2Y, G-protein coupled, 1 3.48168
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 3.47967
AP5S1 adaptor-related protein complex 5, sigma 1 subunit 3.47388
TMEM222 transmembrane protein 222 3.47307
C10ORF120 chromosome 10 open reading frame 120 3.4718
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 3.45634
FAM222B family with sequence similarity 222, member B 3.44766
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 3.43579
XYLT1 xylosyltransferase I 3.4318
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2 3.43041
SBK2 SH3 domain binding kinase family, member 2 3.40538
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 3.38657
MCPH1 microcephalin 1 3.38611
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34 3.38074
GALK1 galactokinase 1 3.38021
HAO1 hydroxyacid oxidase (glycolate oxidase) 1 3.37867
PNOC prepronociceptin 3.36462
ZNF80 zinc finger protein 80 3.36394
CCL27 chemokine (C-C motif) ligand 27 3.36179
WBP4 WW domain binding protein 4 3.36037
SSPN sarcospan 3.33785
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative) 3.32913
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 3.32194
TMEM35 transmembrane protein 35 3.3035
TBC1D19 TBC1 domain family, member 19 3.28061
ANKRD9 ankyrin repeat domain 9 3.27137
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase 3.26778
FAM149B1 family with sequence similarity 149, member B1 3.26573
KLK5 kallikrein-related peptidase 5 3.25426
MCTP1 multiple C2 domains, transmembrane 1 3.25314
GUCY2F guanylate cyclase 2F, retinal 3.24776
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1 3.22555
LRFN2 leucine rich repeat and fibronectin type III domain containing 2 3.22279
FETUB fetuin B 3.21883
YPEL3 yippee-like 3 (Drosophila) 3.20748
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 3.2061
RNF185 ring finger protein 185 3.19724
PLAC8L1 PLAC8-like 1 3.18685
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 3.1762
ZIC3 Zic family member 3 3.17205
FAM20B family with sequence similarity 20, member B 3.16368
GPX7 glutathione peroxidase 7 3.15393
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 3.14948
STARD3 StAR-related lipid transfer (START) domain containing 3 3.14848
PGPEP1L pyroglutamyl-peptidase I-like 3.14713
ZNF346 zinc finger protein 346 3.1421
RBL1 retinoblastoma-like 1 3.13805
KHSRP KH-type splicing regulatory protein 3.1374
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 3.13422
SIX2 SIX homeobox 2 3.13084
TMED1 transmembrane emp24 protein transport domain containing 1 3.1308
NWD1 NACHT and WD repeat domain containing 1 3.09968
CHUK conserved helix-loop-helix ubiquitous kinase 3.09105
FAM91A1 family with sequence similarity 91, member A1 3.08441
OCRL oculocerebrorenal syndrome of Lowe 3.08222
TMEM14B transmembrane protein 14B 3.08184
FGFR1 fibroblast growth factor receptor 1 3.07486
TUBA1A tubulin, alpha 1a 3.07056
ABHD1 abhydrolase domain containing 1 3.06978
ACTA2 actin, alpha 2, smooth muscle, aorta 3.06751
DPEP3 dipeptidase 3 3.05864
C1ORF198 chromosome 1 open reading frame 198 3.05294
STMN3 stathmin-like 3 3.04661
GANC glucosidase, alpha; neutral C 3.0443
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 3.04015
IL22 interleukin 22 3.03784
RCE1 Ras converting CAAX endopeptidase 1 3.03096
RTP5 receptor (chemosensory) transporter protein 5 (putative) 3.03006
LOXL1 lysyl oxidase-like 1 3.02775
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 3.02121
MKRN3 makorin ring finger protein 3 3.018
KIAA0319 KIAA0319 3.01171
CMSS1 cms1 ribosomal small subunit homolog (yeast) 3.0093
DIO2 deiodinase, iodothyronine, type II 3.00621
NXPH3 neurexophilin 3 3.00599
DRD4 dopamine receptor D4 3.00533
S100A16 S100 calcium binding protein A16 2.99882
KIAA1191 KIAA1191 2.98948
FBXL7 F-box and leucine-rich repeat protein 7 2.98776
NUP42 nucleoporin 42 2.98656
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 2.98603
C17ORF98 chromosome 17 open reading frame 98 2.97298
BMX BMX non-receptor tyrosine kinase 2.9708
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 2.96325
PLCXD2 phosphatidylinositol-specific phospholipase C, X domain containing 2 2.96245
GIMAP8 GTPase, IMAP family member 8 2.96099
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 2.9596
TAS2R60 taste receptor, type 2, member 60 2.95876
LGI1 leucine-rich, glioma inactivated 1 2.94596
NAPB N-ethylmaleimide-sensitive factor attachment protein, beta 2.94558
OR51S1 olfactory receptor, family 51, subfamily S, member 1 2.94352
ZSCAN2 zinc finger and SCAN domain containing 2 2.94275
RASIP1 Ras interacting protein 1 2.94165
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 2.93562
FOXE3 forkhead box E3 2.93491
C1ORF177 chromosome 1 open reading frame 177 2.93325
GPC1 glypican 1 2.9257
ATRX alpha thalassemia/mental retardation syndrome X-linked 2.92519
CEP295 centrosomal protein 295kDa 2.91899
FBXO3 F-box protein 3 2.91553
KDM5B lysine (K)-specific demethylase 5B 2.9102
FOXN4 forkhead box N4 2.90992
EPS8L2 EPS8-like 2 2.90987
ASGR1 asialoglycoprotein receptor 1 2.90825
TRAPPC9 trafficking protein particle complex 9 2.88839
PLSCR5 phospholipid scramblase family, member 5 2.88799
ING5 inhibitor of growth family, member 5 2.88098
FBXO30 F-box protein 30 2.86451
PLD2 phospholipase D2 2.85852
LY6G5C lymphocyte antigen 6 complex, locus G5C 2.85284
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 2.84686
FGF10 fibroblast growth factor 10 2.84451
TSHZ3 teashirt zinc finger homeobox 3 2.84238
CTSC cathepsin C 2.84134
PLSCR4 phospholipid scramblase 4 2.84
TDP2 tyrosyl-DNA phosphodiesterase 2 2.83304
WFDC6 WAP four-disulfide core domain 6 2.832
COL4A5 collagen, type IV, alpha 5 2.83118
TMEM39A transmembrane protein 39A 2.82938
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 2.82773
ADGRB2 adhesion G protein-coupled receptor B2 2.82215
ARID3C AT rich interactive domain 3C (BRIGHT-like) 2.82211
UNC119 unc-119 homolog (C. elegans) 2.81966
GPR45 G protein-coupled receptor 45 2.81612
MIEF2 mitochondrial elongation factor 2 2.81493
ZNF606 zinc finger protein 606 2.81177
SLC26A5 solute carrier family 26 (anion exchanger), member 5 2.8095
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 2.80874
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 2.80107
MNMIP1 manchette microtubule inner protein 1 2.80052
METTL7B methyltransferase like 7B 2.79972
PLP1 proteolipid protein 1 2.79068
IQCH IQ motif containing H 2.78227
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 2.77515
HHATL hedgehog acyltransferase-like 2.77139
FBXW9 F-box and WD repeat domain containing 9 2.76576
PMEPA1 prostate transmembrane protein, androgen induced 1 2.74686
PCDHAC1 protocadherin alpha subfamily C, 1 2.7445
BCDIN3D BCDIN3 domain containing 2.74367
SERTAD1 SERTA domain containing 1 2.74036
KDM4B lysine (K)-specific demethylase 4B 2.73613
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 2.73032
TDRD1 tudor domain containing 1 2.72878
SDCBP syndecan binding protein (syntenin) 2.72477
CCDC74B coiled-coil domain containing 74B 2.72307
CEP135 centrosomal protein 135kDa 2.71986
FAIM2 Fas apoptotic inhibitory molecule 2 2.71854
CCDC85A coiled-coil domain containing 85A 2.71601
SCYL2 SCY1-like 2 (S. cerevisiae) 2.7118
MC5R melanocortin 5 receptor 2.71086
PLPP3 phospholipid phosphatase 3 2.70917
MRNIP MRN complex interacting protein 2.70511
DPPA5 developmental pluripotency associated 5 2.69872
CORO1C coronin, actin binding protein, 1C 2.69336
KMT2B lysine (K)-specific methyltransferase 2B 2.69183
VIL1 villin 1 2.68577
USH1C Usher syndrome 1C (autosomal recessive, severe) 2.68326
LDLRAD1 low density lipoprotein receptor class A domain containing 1 2.67991
WNT5A wingless-type MMTV integration site family, member 5A 2.67703
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 2.66458
NPDC1 neural proliferation, differentiation and control, 1 2.65512
MICU2 mitochondrial calcium uptake 2 2.65472
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 2.65429
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) 2.64925
POF1B premature ovarian failure, 1B 2.64515
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase 2.64414
ADCY3 adenylate cyclase 3 2.6433
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1 2.643
CRYZ crystallin, zeta (quinone reductase) 2.64122
OR8A1 olfactory receptor, family 8, subfamily A, member 1 2.6409
ITK IL2-inducible T-cell kinase 2.6392
WNT16 wingless-type MMTV integration site family, member 16 2.62949
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 2.62808
RDM1 RAD52 motif containing 1 2.62695
ASPRV1 aspartic peptidase, retroviral-like 1 2.62087
RCCD1 RCC1 domain containing 1 2.61689
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.61558
ZC3H7A zinc finger CCCH-type containing 7A 2.61547
B3GAT3 beta-1,3-glucuronyltransferase 3 2.60428
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 2.60317
ZDHHC15 zinc finger, DHHC-type containing 15 2.60206
CEP131 centrosomal protein 131kDa 2.6009
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 2.59961
CHRM2 cholinergic receptor, muscarinic 2 2.59706
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 2.58764
KRT7 keratin 7, type II 2.58677
ZNF687 zinc finger protein 687 2.58491
TCEANC2 transcription elongation factor A (SII) N-terminal and central domain containing 2 2.58347
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 2.58099
NPY5R neuropeptide Y receptor Y5 2.58011
CSF1R colony stimulating factor 1 receptor 2.57806
UCN2 urocortin 2 2.57678
CLIC4 chloride intracellular channel 4 2.57493
TACR1 tachykinin receptor 1 2.57279
EDA ectodysplasin A 2.5611
NDEL1 nudE neurodevelopment protein 1-like 1 2.56029
ADRA1B adrenoceptor alpha 1B 2.56006
MEMO1 mediator of cell motility 1 2.55886
PNLIPRP1 pancreatic lipase-related protein 1 2.55442
RELL2 RELT-like 2 2.55012
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 2.54735
TGFBR3 transforming growth factor, beta receptor III 2.54316
OR5K4 olfactory receptor, family 5, subfamily K, member 4 2.54108
CKAP4 cytoskeleton-associated protein 4 2.53794
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 2.53701
ACBD4 acyl-CoA binding domain containing 4 2.53515
CARD10 caspase recruitment domain family, member 10 2.52035
TGM1 transglutaminase 1 2.51659
DNASE1 deoxyribonuclease I 2.5143
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 2.51394
PTCHD1 patched domain containing 1 2.51344
AKAP1 A kinase (PRKA) anchor protein 1 2.51309
ZNF789 zinc finger protein 789 2.51288
AP3M2 adaptor-related protein complex 3, mu 2 subunit 2.50612
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.50158
PDE4C phosphodiesterase 4C, cAMP-specific 2.50108
POLN polymerase (DNA directed) nu 2.49874
EXTL1 exostosin-like glycosyltransferase 1 2.49742
HOMER3 homer scaffolding protein 3 2.49613
GPR19 G protein-coupled receptor 19 2.49605
KLC4 kinesin light chain 4 2.49417
RAP1GAP2 RAP1 GTPase activating protein 2 2.49285
VSX2 visual system homeobox 2 2.49074
EXTL3 exostosin-like glycosyltransferase 3 2.49012
PRRC1 proline-rich coiled-coil 1 2.48973
KRT33A keratin 33A, type I 2.48871
CCDC158 coiled-coil domain containing 158 2.48501
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.48425
SH3TC1 SH3 domain and tetratricopeptide repeats 1 2.47885
C2ORF78 chromosome 2 open reading frame 78 2.47539
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 2.47467
NLGN3 neuroligin 3 2.47437
KCNK6 potassium channel, two pore domain subfamily K, member 6 2.47264
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) 2.47237
ZBTB48 zinc finger and BTB domain containing 48 2.47085
LYRM9 LYR motif containing 9 2.47052
PDZD2 PDZ domain containing 2 2.46865
BDNF brain-derived neurotrophic factor 2.46562
AKIP1 A kinase (PRKA) interacting protein 1 2.46277
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 2.46007
RSAD2 radical S-adenosyl methionine domain containing 2 2.45667
KLHL11 kelch-like family member 11 2.45649
EXT2 exostosin glycosyltransferase 2 2.45477
GPAT3 glycerol-3-phosphate acyltransferase 3 2.45345
CNR2 cannabinoid receptor 2 (macrophage) 2.45218
CD34 CD34 molecule 2.4465
CRYBA1 crystallin, beta A1 2.44453
WASL Wiskott-Aldrich syndrome-like 2.44437
HCRTR1 hypocretin (orexin) receptor 1 2.44294
SYT7 synaptotagmin VII 2.43865
RAD54L RAD54-like (S. cerevisiae) 2.43662
ADIRF adipogenesis regulatory factor 2.43478
ACSM6 acyl-CoA synthetase medium-chain family member 6 2.4327
IER3IP1 immediate early response 3 interacting protein 1 2.42909
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 2.42782
C6ORF141 chromosome 6 open reading frame 141 2.42644
ANXA7 annexin A7 2.42424
CABP4 calcium binding protein 4 2.42146
ZCCHC10 zinc finger, CCHC domain containing 10 2.41863
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G 2.41662
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 2.41614
CCDC28B coiled-coil domain containing 28B 2.41572
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5 2.41352
PPP1R1C protein phosphatase 1, regulatory (inhibitor) subunit 1C 2.40931
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 2.40862
PLIN2 perilipin 2 2.40625
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 2.40617
IL12RB2 interleukin 12 receptor, beta 2 2.40588
C6ORF47 chromosome 6 open reading frame 47 2.40349
CDV3 CDV3 homolog (mouse) 2.4032
BEND2 BEN domain containing 2 2.40146
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.40128
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I 2.40047
LBX2 ladybird homeobox 2 2.39953
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 2.39624
PDLIM2 PDZ and LIM domain 2 (mystique) 2.38867
TPM2 tropomyosin 2 (beta) 2.38657
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 2.3861
EXT1 exostosin glycosyltransferase 1 2.37966
FAM168B family with sequence similarity 168, member B 2.3717
RSPO3 R-spondin 3 2.36802
PLEKHM3 pleckstrin homology domain containing, family M, member 3 2.36446
ANKRD52 ankyrin repeat domain 52 2.36394
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.36016
ARHGAP26 Rho GTPase activating protein 26 2.35823
UBE2E1 ubiquitin-conjugating enzyme E2E 1 2.35818
GDF3 growth differentiation factor 3 2.35729
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2 2.34175
ZBTB5 zinc finger and BTB domain containing 5 2.34078
DCDC2B doublecortin domain containing 2B 2.33678
ZNF443 zinc finger protein 443 2.32959
FBXO48 F-box protein 48 2.32573
TEAD3 TEA domain family member 3 2.32551
IL17RC interleukin 17 receptor C 2.3198
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 2.31395
PTPRU protein tyrosine phosphatase, receptor type, U 2.31386
S100PBP S100P binding protein 2.31378
TWF1 twinfilin actin binding protein 1 2.30992
GRK7 G protein-coupled receptor kinase 7 2.30709
IFT27 intraflagellar transport 27 2.30275
ZNF280B zinc finger protein 280B 2.30148
ATF3 activating transcription factor 3 2.30085
TTC17 tetratricopeptide repeat domain 17 2.2997
CIAO2A cytosolic iron-sulfur assembly component 2A 2.29812
TOR1AIP2 torsin A interacting protein 2 2.29391
CCL17 chemokine (C-C motif) ligand 17 2.28999
TMEM69 transmembrane protein 69 2.28832
RNF6 ring finger protein (C3H2C3 type) 6 2.28778
CACNB1 calcium channel, voltage-dependent, beta 1 subunit 2.28765
MBTD1 mbt domain containing 1 2.28659
TEX15 testis expressed 15 2.2832
LCA5L Leber congenital amaurosis 5-like 2.28304
ATG16L2 autophagy related 16-like 2 (S. cerevisiae) 2.28216
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 2.28059
PBX4 pre-B-cell leukemia homeobox 4 2.27877
VIP vasoactive intestinal peptide 2.27827
GRAMD4 GRAM domain containing 4 2.27712
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 2.27657
RSAD1 radical S-adenosyl methionine domain containing 1 2.27414
LRRC40 leucine rich repeat containing 40 2.27127
MED23 mediator complex subunit 23 2.27077
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 2.26925
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 2.26335
POC1A POC1 centriolar protein A 2.25853
DCPS decapping enzyme, scavenger 2.25838
OFD1 oral-facial-digital syndrome 1 2.25758
MSMP microseminoprotein, prostate associated 2.25435
OTOS otospiralin 2.24991
CDHR1 cadherin-related family member 1 2.24208
ZNF174 zinc finger protein 174 2.24175
BAIAP2L1 BAI1-associated protein 2-like 1 2.24121
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1 2.2372
SCN10A sodium channel, voltage gated, type X alpha subunit 2.23647
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 2.23438
THRA thyroid hormone receptor, alpha 2.23387
KDF1 keratinocyte differentiation factor 1 2.23131
SPATS1 spermatogenesis associated, serine-rich 1 2.22836
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 2.22783
ZFP41 ZFP41 zinc finger protein 2.22663
CEP112 centrosomal protein 112kDa 2.2263
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 2.22448
SP5 Sp5 transcription factor 2.22363
SLURP1 secreted LY6/PLAUR domain containing 1 2.20443
CFDP1 craniofacial development protein 1 2.20153
NMUR2 neuromedin U receptor 2 2.19243
C19ORF24 chromosome 19 open reading frame 24 2.19183
FAM8A1 family with sequence similarity 8, member A1 2.19091
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.18522
SORBS1 sorbin and SH3 domain containing 1 2.17644
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 2.17598
TOMM5 translocase of outer mitochondrial membrane 5 homolog (yeast) 2.17201
TCTN3 tectonic family member 3 2.16767
HFE hemochromatosis 2.1661
CNGB3 cyclic nucleotide gated channel beta 3 2.16114
FAM167B family with sequence similarity 167, member B 2.15952
GRN granulin 2.15897
ARHGAP17 Rho GTPase activating protein 17 2.15801
ZBTB7B zinc finger and BTB domain containing 7B 2.15638
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 2.15379
PSPN persephin 2.14577
CBX6 chromobox homolog 6 2.14476
PCDHB5 protocadherin beta 5 2.14124
SNRPA small nuclear ribonucleoprotein polypeptide A 2.14117
GCAT glycine C-acetyltransferase 2.14077
GPR162 G protein-coupled receptor 162 2.13755
PUS10 pseudouridylate synthase 10 2.13121
FAM69C family with sequence similarity 69, member C 2.13018
BPIFB2 BPI fold containing family B, member 2 2.12782
POU5F2 POU domain class 5, transcription factor 2 2.12733
H1-2 H1.2 linker histone, cluster member 2.12687
MMD monocyte to macrophage differentiation-associated 2.12477
KIAA0141 KIAA0141 2.12459
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 2.12194
ZYG11B zyg-11 family member B, cell cycle regulator 2.12035
SPOCD1 SPOC domain containing 1 2.11968
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 2.11612
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.116
APOC2 apolipoprotein C-II 2.11541
PMM2 phosphomannomutase 2 2.10261
NYNRIN NYN domain and retroviral integrase containing 2.09896
CYTH3 cytohesin 3 2.09863
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae) 2.09619
POR P450 (cytochrome) oxidoreductase 2.09456
TMEM40 transmembrane protein 40 2.09397
SP2 Sp2 transcription factor 2.09373
ADM adrenomedullin 2.0895
C19ORF12 chromosome 19 open reading frame 12 2.08885
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 2.08517
NOXO1 NADPH oxidase organizer 1 2.08442
ADGRG4 adhesion G protein-coupled receptor G4 2.08363
ERCC5 excision repair cross-complementation group 5 2.08315
RAB31 RAB31, member RAS oncogene family 2.08311
THBD thrombomodulin 2.08235
USP1 ubiquitin specific peptidase 1 2.08111
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 2.08068
AVPR1A arginine vasopressin receptor 1A 2.08065
GTDC1 glycosyltransferase-like domain containing 1 2.07854
EGR4 early growth response 4 2.0784
PTGDR2 prostaglandin D2 receptor 2 2.07695
PCOLCE2 procollagen C-endopeptidase enhancer 2 2.07569
XYLT2 xylosyltransferase II 2.0751
LIN37 lin-37 DREAM MuvB core complex component 2.07079
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 2.06946
GATAD2A GATA zinc finger domain containing 2A 2.06712
HUS1B HUS1 checkpoint homolog b (S. pombe) 2.06586
FFAR4 free fatty acid receptor 4 2.06509
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 2.06432
GSDME gasdermin E 2.06344
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like 2.06229
PIGU phosphatidylinositol glycan anchor biosynthesis, class U 2.06052
ZMIZ2 zinc finger, MIZ-type containing 2 2.05762
KLHDC8B kelch domain containing 8B 2.05678
DAAM1 dishevelled associated activator of morphogenesis 1 2.05569
PTOV1 prostate tumor overexpressed 1 2.05549
LSM1 LSM1, U6 small nuclear RNA associated 2.05535
HNMT histamine N-methyltransferase 2.05069
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 2.05069
ITGA7 integrin, alpha 7 2.05024
RHCG Rh family, C glycoprotein 2.04941
IL21R interleukin 21 receptor 2.04708
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2 2.04591
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 2.04579
PPP1R3B protein phosphatase 1, regulatory subunit 3B 2.04165
PAPL iron/zinc purple acid phosphatase-like protein 2.04049
STH saitohin 2.03743
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 2.03196
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 2.02626
C9ORF3 chromosome 9 open reading frame 3 2.02604
SEPP1 selenoprotein P, plasma, 1 2.02267
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 2.02179
EVA1A eva-1 homolog A (C. elegans) 2.01942
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1 2.01754
DTX4 deltex 4, E3 ubiquitin ligase 2.01447
ASS1 argininosuccinate synthase 1 2.01327
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus 2.01242
MTNR1B melatonin receptor 1B 2.00876
ERBIN erbb2 interacting protein 2.00788
TMEM214 transmembrane protein 214 2.00771
HOXA9 homeobox A9 2.00502
SLIT2 slit homolog 2 (Drosophila) 2.00436
NCOR1 nuclear receptor corepressor 1 2.00314
NBR1 neighbor of BRCA1 gene 1 2.00205
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 2.00169
BANF2 barrier to autointegration factor 2 2.00007