MERTK Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description MER proto-oncogene, tyrosine kinase|This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 10461)
External Link https://ncbi.nlm.nih.gov/gene/10461
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Genes

499 genes differentially expressed following the MERTK gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
RTN2 reticulon 2 0.0177086
PCNA proliferating cell nuclear antigen 0.0168564
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.0156903
TUBB2B tubulin, beta 2B class IIb 0.0142926
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.0140799
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 0.0136816
CRABP1 cellular retinoic acid binding protein 1 0.0126966
OXA1L oxidase (cytochrome c) assembly 1-like 0.0121318
AK1 adenylate kinase 1 0.0120368
MX1 MX dynamin-like GTPase 1 0.0120268
ZIC1 Zic family member 1 0.011727
CXCL8 chemokine (C-X-C motif) ligand 8 0.0116013
IFITM3 interferon induced transmembrane protein 3 0.0113792
CRYAB crystallin, alpha B 0.0108358
PITX3 paired-like homeodomain 3 0.0106592
ASS1 argininosuccinate synthase 1 0.0106352
HSPA1A heat shock 70kDa protein 1A 0.0105882
IFITM2 interferon induced transmembrane protein 2 0.0105656
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.0104174
STMN2 stathmin 2 0.0103726
TSPO translocator protein (18kDa) 0.0100968
DLK1 delta-like 1 homolog (Drosophila) 0.0100576
MFSD10 major facilitator superfamily domain containing 10 0.010015
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00989623
SRPX sushi-repeat containing protein, X-linked 0.00982432
PDLIM4 PDZ and LIM domain 4 0.00940445
C10ORF10 chromosome 10 open reading frame 10 0.00931496
PLS3 plastin 3 0.00930038
IFI44L interferon-induced protein 44-like 0.00923531
THBS2 thrombospondin 2 0.00922737
IL32 interleukin 32 0.00900302
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.0089569
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00891638
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.00878922
TPPP3 tubulin polymerization-promoting protein family member 3 0.00876023
MAB21L1 mab-21-like 1 (C. elegans) 0.00871311
IFI6 interferon, alpha-inducible protein 6 0.00863549
HSPB1 heat shock 27kDa protein 1 0.00861479
CALR calreticulin 0.00849395
ETFB electron-transfer-flavoprotein, beta polypeptide 0.00846147
C14ORF132 chromosome 14 open reading frame 132 0.00840754
NEFM neurofilament, medium polypeptide 0.0083843
TSPAN8 tetraspanin 8 0.00837497
PLAAT3 phospholipase A and acyltransferase 3 0.00836719
EIF3F eukaryotic translation initiation factor 3, subunit F 0.00835693
IFRD2 interferon-related developmental regulator 2 0.00828259
MX2 MX dynamin-like GTPase 2 0.00821948
ARMCX1 armadillo repeat containing, X-linked 1 0.0082184
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 0.00819826
SLC43A3 solute carrier family 43, member 3 0.0081727
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00817259
TRIM22 tripartite motif containing 22 0.00817077
RGS3 regulator of G-protein signaling 3 0.00814693
PKN1 protein kinase N1 0.00812114
MVP major vault protein 0.00808077
MIA melanoma inhibitory activity 0.00807038
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 0.00802387
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00801899
ATF4 activating transcription factor 4 0.00801143
CALCA calcitonin-related polypeptide alpha 0.00800803
SOX9 SRY (sex determining region Y)-box 9 0.00799233
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.00797363
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00790833
PEG10 paternally expressed 10 0.00786699
LRRC8D leucine rich repeat containing 8 family, member D 0.00782202
JMJD6 jumonji domain containing 6 0.00772194
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00769664
TRIB3 tribbles pseudokinase 3 0.00761043
PXDN peroxidasin 0.00759084
LIMCH1 LIM and calponin homology domains 1 0.00753097
PTPRE protein tyrosine phosphatase, receptor type, E 0.00750512
RFTN1 raftlin, lipid raft linker 1 0.00747515
HSPA8 heat shock 70kDa protein 8 0.00744385
MBL2 mannose-binding lectin (protein C) 2, soluble 0.00743621
IGFBP6 insulin-like growth factor binding protein 6 0.00743532
MB myoglobin 0.00740343
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 0.00739904
NES nestin 0.00738335
NEFH neurofilament, heavy polypeptide 0.00737398
LGALS4 lectin, galactoside-binding, soluble, 4 0.0073587
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.00735589
IFI44 interferon-induced protein 44 0.00733565
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.00732143
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 0.00730478
TCTA T-cell leukemia translocation altered 0.00728145
MT1E metallothionein 1E 0.00719684
SELENOW selenoprotein W 0.0071869
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.00717749
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 0.00716715
FAM110B family with sequence similarity 110, member B 0.0070994
BIN1 bridging integrator 1 0.00709443
AREG amphiregulin 0.00706441
RABAC1 Rab acceptor 1 (prenylated) 0.00705014
IFRD1 interferon-related developmental regulator 1 0.0070329
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.00700641
TIMP2 TIMP metallopeptidase inhibitor 2 0.00699438
KRT14 keratin 14, type I 0.00698749
MT1X metallothionein 1X 0.00698515
TUBB3 tubulin, beta 3 class III 0.00697079
PRKCSH protein kinase C substrate 80K-H 0.00694823
SPRED2 sprouty-related, EVH1 domain containing 2 0.00693881
GAP43 growth associated protein 43 0.0069373
ACSL1 acyl-CoA synthetase long-chain family member 1 0.00691266
OXTR oxytocin receptor 0.00690998
MRPL23 mitochondrial ribosomal protein L23 0.00690984
SYBU syntabulin (syntaxin-interacting) 0.00688034
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle 0.00687785
SPATA20 spermatogenesis associated 20 0.00687347
TBCB tubulin folding cofactor B 0.00684456
NUPR1 nuclear protein, transcriptional regulator, 1 0.00684373
MDK midkine (neurite growth-promoting factor 2) 0.00681627
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.00681526
ISG15 ISG15 ubiquitin-like modifier 0.00681276
MEN1 multiple endocrine neoplasia I 0.00679347
TM4SF1 transmembrane 4 L six family member 1 0.00678876
EFNA1 ephrin-A1 0.00677492
NPEPL1 aminopeptidase-like 1 0.00677442
PKM pyruvate kinase, muscle 0.0067638
RUNX1 runt-related transcription factor 1 0.00674892
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.00674427
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00674172
SYT11 synaptotagmin XI 0.00673355
NID1 nidogen 1 0.00672583
DRAM1 DNA-damage regulated autophagy modulator 1 0.00670699
PDGFRL platelet-derived growth factor receptor-like 0.00667151
IRS2 insulin receptor substrate 2 0.00667083
SLC22A18 solute carrier family 22, member 18 0.00664529
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.0066172
RELN reelin 0.00657369
PPDPF pancreatic progenitor cell differentiation and proliferation factor 0.00657039
CCL20 chemokine (C-C motif) ligand 20 0.00656247
IRF7 interferon regulatory factor 7 0.00654653
LONP1 lon peptidase 1, mitochondrial 0.0065437
ATP5F1D ATP synthase F1 subunit delta 0.00653549
MXRA7 matrix-remodelling associated 7 0.00652488
CORO2B coronin, actin binding protein, 2B 0.00651587
GLS glutaminase 0.00651316
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.00650752
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00650047
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00647298
GARS1 glycyl-tRNA synthetase 1 0.00645633
CELF2 CUGBP, Elav-like family member 2 0.00644893
UBXN1 UBX domain protein 1 0.00644788
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.00644502
BAX BCL2-associated X protein 0.00644222
GSTP1 glutathione S-transferase pi 1 0.0064254
COL9A2 collagen, type IX, alpha 2 0.00640839
PDLIM2 PDZ and LIM domain 2 (mystique) 0.00640094
BCL3 B-cell CLL/lymphoma 3 0.0063859
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 0.00637837
PCBP4 poly(rC) binding protein 4 0.00636285
SF3A2 splicing factor 3a, subunit 2, 66kDa 0.00634485
GPX1 glutathione peroxidase 1 0.00634328
PTPRA protein tyrosine phosphatase, receptor type, A 0.00634324
HMGA1 high mobility group AT-hook 1 0.00634202
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 0.00633649
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.00633489
ZNF580 zinc finger protein 580 0.00633405
HLA-B major histocompatibility complex, class I, B 0.00632851
TUBA4A tubulin, alpha 4a 0.00631855
TMEM131L transmembrane 131 like 0.00631498
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.00631128
PFKM phosphofructokinase, muscle 0.00630247
CTSG cathepsin G 0.0062982
PCOLCE procollagen C-endopeptidase enhancer 0.00629219
COL16A1 collagen, type XVI, alpha 1 0.00629174
ARFIP2 ADP-ribosylation factor interacting protein 2 0.00628754
REPIN1 replication initiator 1 0.00627652
TFPI2 tissue factor pathway inhibitor 2 0.00627424
NOP56 NOP56 ribonucleoprotein 0.0062486
DOK5 docking protein 5 0.00623506
APH1A APH1A gamma secretase subunit 0.00622751
PHYH phytanoyl-CoA 2-hydroxylase 0.00620497
RUVBL2 RuvB-like AAA ATPase 2 0.00619988
RPS17 ribosomal protein S17 0.00615917
SP100 SP100 nuclear antigen 0.00615249
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.00613357
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.00612094
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B 0.00611029
PDE4DIP phosphodiesterase 4D interacting protein 0.00609
CCDC28B coiled-coil domain containing 28B 0.00608264
EDF1 endothelial differentiation-related factor 1 0.00604768
H1-0 H1.0 linker histone 0.00602444
RPL36 ribosomal protein L36 0.0060177
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.00601561
NAV2 neuron navigator 2 0.00601421
CFB complement factor B 0.00600021
KIF1A kinesin family member 1A 0.0059846
S100A11 S100 calcium binding protein A11 0.00597475
PLLP plasmolipin 0.00597428
BEX1 brain expressed, X-linked 1 0.00597052
FKBP9 FK506 binding protein 9, 63 kDa 0.00595871
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 0.00595339
MAP2K2 mitogen-activated protein kinase kinase 2 0.00593028
FXYD5 FXYD domain containing ion transport regulator 5 0.00592782
CAND2 cullin-associated and neddylation-dissociated 2 (putative) 0.00592632
RGS16 regulator of G-protein signaling 16 0.00592369
RBM42 RNA binding motif protein 42 0.0059212
NACAD NAC alpha domain containing 0.00590592
TNIP1 TNFAIP3 interacting protein 1 0.00590246
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.00589744
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 0.0058929
ARHGAP17 Rho GTPase activating protein 17 0.00589028
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 0.00587453
LTBP2 latent transforming growth factor beta binding protein 2 0.00586948
OLFML2A olfactomedin-like 2A 0.005862
SCAMP4 secretory carrier membrane protein 4 0.00585272
CAVIN3 caveolae associated protein 3 0.00583974
TNNC1 troponin C type 1 (slow) 0.00582463
LIF leukemia inhibitory factor 0.00582085
PUM3 pumilio RNA binding family member 3 0.00581271
POPDC3 popeye domain containing 3 0.0058065
PEG3 paternally expressed 3 0.00580541
EPB41L3 erythrocyte membrane protein band 4.1-like 3 0.00579048
FADS3 fatty acid desaturase 3 0.00578936
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00578803
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 0.00578192
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.00577976
SPRY4 sprouty homolog 4 (Drosophila) 0.00577969
AMOTL2 angiomotin like 2 0.00577645
YARS1 tyrosyl-tRNA synthetase 1 0.00575731
COL9A3 collagen, type IX, alpha 3 0.00575504
AGRN agrin 0.0057306
NINJ1 ninjurin 1 0.00572213
ACADVL acyl-CoA dehydrogenase, very long chain 0.00572145
MID1IP1 MID1 interacting protein 1 0.00569073
CCP110 centriolar coiled coil protein 110kDa 0.0056853
RYR1 ryanodine receptor 1 (skeletal) 0.00566596
VGLL4 vestigial-like family member 4 0.00565926
RET ret proto-oncogene 0.00565743
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.00565695
CDR2L cerebellar degeneration-related protein 2-like 0.00564058
ENG endoglin 0.0056311
PADI2 peptidyl arginine deiminase, type II 0.00563021
ZBTB18 zinc finger and BTB domain containing 18 0.00561741
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 0.00561718
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 0.00561038
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.00560729
QSOX1 quiescin Q6 sulfhydryl oxidase 1 0.00560496
CLCN4 chloride channel, voltage-sensitive 4 0.00560097
GAB2 GRB2-associated binding protein 2 0.0055807
BMP2 bone morphogenetic protein 2 0.00557109
FBXL14 F-box and leucine-rich repeat protein 14 0.00556537
TSPAN14 tetraspanin 14 0.0055642
UROD uroporphyrinogen decarboxylase 0.00556236
TUFM Tu translation elongation factor, mitochondrial 0.00556212
CREB3L1 cAMP responsive element binding protein 3-like 1 0.00554876
HMOX1 heme oxygenase 1 0.00554791
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.00553573
EXT1 exostosin glycosyltransferase 1 0.005528

decreased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 -0.0191381
FGFR3 fibroblast growth factor receptor 3 -0.0166713
S100P S100 calcium binding protein P -0.0161117
KYNU kynureninase -0.0152419
S100A8 S100 calcium binding protein A8 -0.0146078
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.0144339
NUSAP1 nucleolar and spindle associated protein 1 -0.014078
UPK1B uroplakin 1B -0.0127054
AQP3 aquaporin 3 (Gill blood group) -0.0124592
AKR1C3 aldo-keto reductase family 1, member C3 -0.0115542
COL4A6 collagen, type IV, alpha 6 -0.011549
PERP PERP, TP53 apoptosis effector -0.0114545
COL4A5 collagen, type IV, alpha 5 -0.011145
FOXF1 forkhead box F1 -0.0108685
PALLD palladin, cytoskeletal associated protein -0.0108096
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.0107289
SPARCL1 SPARC-like 1 (hevin) -0.0106745
NPR3 natriuretic peptide receptor 3 -0.0105976
CST1 cystatin SN -0.0105073
CPA3 carboxypeptidase A3 (mast cell) -0.0104611
SKAP2 src kinase associated phosphoprotein 2 -0.0103646
CXCL9 chemokine (C-X-C motif) ligand 9 -0.0103302
ITGA6 integrin, alpha 6 -0.0102895
ESR1 estrogen receptor 1 -0.0100495
ANO1 anoctamin 1, calcium activated chloride channel -0.0100268
MMP7 matrix metallopeptidase 7 -0.00999009
MEIS2 Meis homeobox 2 -0.00986126
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00981787
SH3BGRL SH3 domain binding glutamate-rich protein like -0.00981089
CCL19 chemokine (C-C motif) ligand 19 -0.00980287
TMEM106B transmembrane protein 106B -0.00973048
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00972393
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) -0.00957573
DMTF1 cyclin D binding myb-like transcription factor 1 -0.0095374
CALD1 caldesmon 1 -0.00947768
TXNIP thioredoxin interacting protein -0.00945922
KRT6A keratin 6A, type II -0.0093976
ADAM28 ADAM metallopeptidase domain 28 -0.00934132
GLIPR1 GLI pathogenesis-related 1 -0.00931697
SLPI secretory leukocyte peptidase inhibitor -0.00931123
LYPLA1 lysophospholipase I -0.00923519
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.0091964
LEF1 lymphoid enhancer-binding factor 1 -0.00915426
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00914814
METTL7A methyltransferase like 7A -0.00906353
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.00893047
PBX1 pre-B-cell leukemia homeobox 1 -0.00892787
MREG melanoregulin -0.00891879
SUB1 SUB1 homolog (S. cerevisiae) -0.0088855
PLPP3 phospholipid phosphatase 3 -0.00886622
AMIGO2 adhesion molecule with Ig-like domain 2 -0.0088319
S100A9 S100 calcium binding protein A9 -0.00876458
BANK1 B-cell scaffold protein with ankyrin repeats 1 -0.00876101
CSTA cystatin A (stefin A) -0.0086882
TMEM47 transmembrane protein 47 -0.00866671
GUCY1B3 guanylate cyclase 1, soluble, beta 3 -0.00862699
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.008515
SPRR1B small proline-rich protein 1B -0.00851113
SPRR3 small proline-rich protein 3 -0.00847599
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.0084749
DIO2 deiodinase, iodothyronine, type II -0.00837728
CORO1C coronin, actin binding protein, 1C -0.00837202
CAV1 caveolin 1, caveolae protein, 22kDa -0.00836959
TACSTD2 tumor-associated calcium signal transducer 2 -0.0083663
TSC22D1 TSC22 domain family, member 1 -0.00834401
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00833161
CTSK cathepsin K -0.00822712
S100A7 S100 calcium binding protein A7 -0.00819671
LGALS2 lectin, galactoside-binding, soluble, 2 -0.00818411
MRTFB myocardin related transcription factor B -0.00816632
FZD5 frizzled class receptor 5 -0.0081319
ALOX5 arachidonate 5-lipoxygenase -0.00812923
STOM stomatin -0.00807546
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -0.00802849
VAMP7 vesicle-associated membrane protein 7 -0.00802439
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.00798632
TRAM1 translocation associated membrane protein 1 -0.00798009
CASP8 caspase 8, apoptosis-related cysteine peptidase -0.00796323
PRKCB protein kinase C, beta -0.00795887
SERINC5 serine incorporator 5 -0.00794767
NRGN neurogranin (protein kinase C substrate, RC3) -0.00794423
COL15A1 collagen, type XV, alpha 1 -0.0079221
GLUL glutamate-ammonia ligase -0.00791417
PLN phospholamban -0.00791381
CAV2 caveolin 2 -0.00790871
S100A2 S100 calcium binding protein A2 -0.00789584
KRT13 keratin 13, type I -0.00781641
OLFM4 olfactomedin 4 -0.00776515
NPY1R neuropeptide Y receptor Y1 -0.00767574
TSPAN13 tetraspanin 13 -0.00767163
LTF lactotransferrin -0.00766941
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.00766537
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00766043
HLA-DOB major histocompatibility complex, class II, DO beta -0.00762831
EPCAM epithelial cell adhesion molecule -0.00761986
PURA purine-rich element binding protein A -0.00760216
MOCS2 molybdenum cofactor synthesis 2 -0.00758482
CPE carboxypeptidase E -0.00757526
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -0.0075111
ALCAM activated leukocyte cell adhesion molecule -0.00750215
EGLN3 egl-9 family hypoxia-inducible factor 3 -0.00748389
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.0074159
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -0.00740921
MEIS1 Meis homeobox 1 -0.00736037
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.00734957
MPZL2 myelin protein zero-like 2 -0.00734392
ELL2 elongation factor, RNA polymerase II, 2 -0.00725705
PRKD3 protein kinase D3 -0.0072455
NTS neurotensin -0.00723581
CRIP1 cysteine-rich protein 1 (intestinal) -0.00723132
RNF14 ring finger protein 14 -0.00717945
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -0.00717433
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.00716447
PON2 paraoxonase 2 -0.00715952
DAPK1 death-associated protein kinase 1 -0.00715742
FGL2 fibrinogen-like 2 -0.00712853
HLA-DMB major histocompatibility complex, class II, DM beta -0.00711213
CDKN3 cyclin-dependent kinase inhibitor 3 -0.00709866
NQO2 NAD(P)H dehydrogenase, quinone 2 -0.00709382
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00707051
EHF ets homologous factor -0.00705972
EPHA4 EPH receptor A4 -0.00704727
GJA1 gap junction protein, alpha 1, 43kDa -0.00703746
SORD sorbitol dehydrogenase -0.00703015
AQP1 aquaporin 1 (Colton blood group) -0.00702879
SRSF1 serine/arginine-rich splicing factor 1 -0.00702437
XIC X chromosome inactivation center -0.00698758
HMMR hyaluronan-mediated motility receptor (RHAMM) -0.00695754
RRM2 ribonucleotide reductase M2 -0.00694566
LYZ lysozyme -0.00694384
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) -0.00694134
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00693315
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.00692866
CD52 CD52 molecule -0.00692018
MMP12 matrix metallopeptidase 12 -0.00690718
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.00687727
FUCA1 fucosidase, alpha-L- 1, tissue -0.00686502
FBXO21 F-box protein 21 -0.0068631
BCHE butyrylcholinesterase -0.00685963
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -0.00684772
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) -0.00684611
ZBTB38 zinc finger and BTB domain containing 38 -0.00683714
RHOB ras homolog family member B -0.00683146
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.0068274
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00682694
TPSAB1 tryptase alpha/beta 1 -0.00680553
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.00680092
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0067978
CLU clusterin -0.00679228
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00679111
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.00676645
MAOA monoamine oxidase A -0.00676592
H2AFV H2A histone family, member V -0.00674006
AGR2 anterior gradient 2 -0.00672356
CD1E CD1e molecule -0.00671519
QPCT glutaminyl-peptide cyclotransferase -0.00671409
PPAP2A phosphatidic acid phosphatase type 2A -0.00668661
CXADR coxsackie virus and adenovirus receptor -0.00668499
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -0.00666438
MAPK1 mitogen-activated protein kinase 1 -0.00666424
RDX radixin -0.00663454
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.00662439
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -0.00661873
PHACTR2 phosphatase and actin regulator 2 -0.00661032
RAB32 RAB32, member RAS oncogene family -0.00660858
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.0065961
CDCA4 cell division cycle associated 4 -0.00655879
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00654003
KANK2 KN motif and ankyrin repeat domains 2 -0.006515
SCAMP1 secretory carrier membrane protein 1 -0.00650662
PJA2 praja ring finger 2, E3 ubiquitin protein ligase -0.00650545
MYH11 myosin, heavy chain 11, smooth muscle -0.00649663
ANXA10 annexin A10 -0.00644539
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -0.00644242
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -0.00644028
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -0.00641787
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.00641372
RIDA reactive intermediate imine deaminase A homolog -0.00641156
MDM1 Mdm1 nuclear protein homolog (mouse) -0.00638926
MCOLN1 mucolipin 1 -0.00637864
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -0.00636319
CCNE2 cyclin E2 -0.00635959
LCN2 lipocalin 2 -0.00635098
CHKB choline kinase beta -0.00633288
NMD3 NMD3 ribosome export adaptor -0.00633069
CD2 CD2 molecule -0.00632866
CLCA2 chloride channel accessory 2 -0.00632809
TSPAN7 tetraspanin 7 -0.00632552
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -0.00631361
FGF13 fibroblast growth factor 13 -0.00630889
WFDC1 WAP four-disulfide core domain 1 -0.00628416
IDO1 indoleamine 2,3-dioxygenase 1 -0.00626526
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.00625521
TGM2 transglutaminase 2 -0.0062516
ANKMY2 ankyrin repeat and MYND domain containing 2 -0.00624894
CCNB1 cyclin B1 -0.00623408
CAND1 cullin-associated and neddylation-dissociated 1 -0.0062333
C7 complement component 7 -0.0062098
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -0.0061862
ACOT13 acyl-CoA thioesterase 13 -0.00618294
CANX calnexin -0.00617186
CA8 carbonic anhydrase VIII -0.00616665
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00616496
CETN2 centrin, EF-hand protein, 2 -0.00615946
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00614286
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.00614209
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.00613579
SPRR1A small proline-rich protein 1A -0.00613219
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.00612457
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -0.00612397
AKAP7 A kinase (PRKA) anchor protein 7 -0.00607174
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -0.00605615
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.00605104
SUZ12 SUZ12 polycomb repressive complex 2 subunit -0.00605023
CCL14 chemokine (C-C motif) ligand 14 -0.00604939
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.00604661
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00603454
IGFBP5 insulin-like growth factor binding protein 5 -0.00603148
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 -0.00599943
ESRP1 epithelial splicing regulatory protein 1 -0.00599589
NCK1 NCK adaptor protein 1 -0.00599143
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -0.00598732
CRISP3 cysteine-rich secretory protein 3 -0.00597908
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.00597788
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 -0.00596937
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00594503
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.00594024
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00593866
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00593802
BIRC3 baculoviral IAP repeat containing 3 -0.00592953
CLDN10 claudin 10 -0.00592762
CKS2 CDC28 protein kinase regulatory subunit 2 -0.00592572
SEPP1 selenoprotein P, plasma, 1 -0.00592113
SPON1 spondin 1, extracellular matrix protein -0.00590178
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.00589737
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -0.00588476
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 -0.00587378
NELL1 NEL-like 1 (chicken) -0.00586312
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 -0.00584552
PDE2A phosphodiesterase 2A, cGMP-stimulated -0.00584144
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -0.00581449
SLC38A6 solute carrier family 38, member 6 -0.00581315
GZMK granzyme K (granzyme 3; tryptase II) -0.0058112
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 -0.00581077
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -0.00581017
SGPP1 sphingosine-1-phosphate phosphatase 1 -0.00579548
CD1C CD1c molecule -0.00579456
HOXA10 homeobox A10 -0.00574382
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.00574266