MERTK Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description MER proto-oncogene, tyrosine kinase|This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 10461)
External Link http://www.ncbi.nlm.nih.gov/gene/10461
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Genes

47 interacting proteins for MERTK from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACAD11 acyl-CoA dehydrogenase family, member 11
ACVR1 activin A receptor, type I
ALK anaplastic lymphoma receptor tyrosine kinase
AURKA aurora kinase A
AURKB aurora kinase B
AXL AXL receptor tyrosine kinase
AZI2 5-azacytidine induced 2
BMP2K BMP2 inducible kinase
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
EPHA2 EPH receptor A2
EPHB4 EPH receptor B4
FER fer (fps/fes related) tyrosine kinase
GAS6 growth arrest-specific 6
GRB2 growth factor receptor-bound protein 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IRAK1 interleukin-1 receptor-associated kinase 1
JAK1 Janus kinase 1
LIMK1 LIM domain kinase 1
LIMK2 LIM domain kinase 2
LMO4 LIM domain only 4
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MST1R macrophage stimulating 1 receptor
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NUAK1 NUAK family, SNF1-like kinase, 1
PKM pyruvate kinase, muscle
PRKD2 protein kinase D2
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
RIPK2 receptor-interacting serine-threonine kinase 2
SLK STE20-like kinase
STK4 serine/threonine kinase 4
TANK TRAF family member-associated NFKB activator
TBK1 TANK-binding kinase 1
TBKBP1 TBK1 binding protein 1
TNK2 tyrosine kinase, non-receptor, 2
TRAF2 TNF receptor-associated factor 2
TYK2 tyrosine kinase 2
UBC ubiquitin C
VAV1 vav 1 guanine nucleotide exchange factor