MET Gene Set

Dataset Kinase Library Tyrosine Kinome Atlas
Category proteomics
Type kinase
Description MET proto-oncogene, receptor tyrosine kinase|The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4233)
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100 substrates of the kinase MET from the Kinase Library Tyrosine Kinome Atlas dataset.

Symbol Name Standardized Value
SIPA1L1 signal-induced proliferation-associated 1 like 1 100.0
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 99.96
N4BP3 NEDD4 binding protein 3 99.91
MCC mutated in colorectal cancers 99.89
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 99.76
ZCCHC3 zinc finger, CCHC domain containing 3 99.74
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 99.71
JUN jun proto-oncogene 99.67
SEC14L2 SEC14-like 2 (S. cerevisiae) 99.59
SEC14L3 SEC14-like 3 (S. cerevisiae) 99.59
TRPV2 transient receptor potential cation channel, subfamily V, member 2 99.56
MCEMP1 mast cell-expressed membrane protein 1 99.54
PARD6B par-6 family cell polarity regulator beta 99.52
ARHGAP30 Rho GTPase activating protein 30 99.5
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 99.37
CNOT9 CCR4-NOT transcription complex subunit 9 99.37
PDCD5 programmed cell death 5 99.36
EIF3I eukaryotic translation initiation factor 3, subunit I 99.25
TNRC6B trinucleotide repeat containing 6B 99.19
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) 99.15
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 99.1
OPHN1 oligophrenin 1 98.99
EIF1B eukaryotic translation initiation factor 1B 98.9
EIF1 eukaryotic translation initiation factor 1 98.9
SH2D1B SH2 domain containing 1B 98.86
CCT8 chaperonin containing TCP1, subunit 8 (theta) 98.84
TRAF3IP2 TRAF3 interacting protein 2 98.77
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 98.75
DLG3 discs, large homolog 3 (Drosophila) 98.74
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 98.71
IRS4 insulin receptor substrate 4 98.69
KAT2B K(lysine) acetyltransferase 2B 98.64
ESYT2 extended synaptotagmin-like protein 2 98.6
IL7R interleukin 7 receptor 98.58
CLEC12B C-type lectin domain family 12, member B 98.56
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 98.55
ATXN1 ataxin 1 98.47
RFTN1 raftlin, lipid raft linker 1 98.36
KAT2A K(lysine) acetyltransferase 2A 98.34
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa 98.32
SH2D3C SH2 domain containing 3C 98.21
BYSL bystin-like 98.1
SRL sarcalumenin 98.03
LST1 leukocyte specific transcript 1 98.01
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 97.9
NFYA nuclear transcription factor Y, alpha 97.81
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 97.68
CHAF1B chromatin assembly factor 1, subunit B (p60) 97.62
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 97.55
MAGED2 melanoma antigen family D2 97.42
LOC102725035 leukocyte immunoglobulin-like receptor subfamily B member 3 97.39
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 97.39
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 97.375
BRIX1 BRX1, biogenesis of ribosomes 97.33
HDAC6 histone deacetylase 6 97.26
CEP170B centrosomal protein 170B 97.24
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 97.22
CKAP4 cytoskeleton-associated protein 4 97.18
CEP68 centrosomal protein 68kDa 97.11
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 97.07
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 97.0
RPL8 ribosomal protein L8 96.98
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 96.94
FCRL3 Fc receptor-like 3 96.935
PTPN7 protein tyrosine phosphatase, non-receptor type 7 96.91
CD300LB CD300 molecule-like family member b 96.89
GCSAML germinal center-associated, signaling and motility-like 96.83
KRT19 keratin 19, type I 96.81
LAX1 lymphocyte transmembrane adaptor 1 96.63
TRIOBP TRIO and F-actin binding protein 96.585
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 96.58
CD3D CD3d molecule, delta (CD3-TCR complex) 96.51
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 96.48
RABGAP1L RAB GTPase activating protein 1-like 96.46
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 96.45
EXPH5 exophilin 5 96.41
CEP43 centrosomal protein 43 96.34
STARD13 StAR-related lipid transfer (START) domain containing 13 96.3
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing 96.26
FCRL6 Fc receptor-like 6 96.23
EML4 echinoderm microtubule associated protein like 4 96.21
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 96.15
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 96.13
CHRM2 cholinergic receptor, muscarinic 2 96.1
FHIT fragile histidine triad 96.06
PILRA paired immunoglobin-like type 2 receptor alpha 96.02
USP31 ubiquitin specific peptidase 31 96.0
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 95.99
CD3G CD3g molecule, gamma (CD3-TCR complex) 95.975
SRCIN1 SRC kinase signaling inhibitor 1 95.965
ZNF512 zinc finger protein 512 95.93
TPRN taperin 95.84
MAT2A methionine adenosyltransferase II, alpha 95.82
PLS3 plastin 3 95.78
CD300LF CD300 molecule-like family member f 95.78
THEMIS2 thymocyte selection associated family member 2 95.58
PM20D2 peptidase M20 domain containing 2 95.4
ARHGAP35 Rho GTPase activating protein 35 95.385
CD300A CD300a molecule 95.345
PBK PDZ binding kinase 95.25