MET_knockout_253_GSE30651 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE30651
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Genes

600 genes differentially expressed following the MET_knockout_253_GSE30651 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
STX18 syntaxin 18 3.55615
EGLN2 egl-9 family hypoxia-inducible factor 2 3.44666
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) 3.14352
KEAP1 kelch-like ECH-associated protein 1 3.00079
TTC36 tetratricopeptide repeat domain 36 2.98754
ADIPOR2 adiponectin receptor 2 2.94237
POLR1C polymerase (RNA) I polypeptide C, 30kDa 2.89937
C19ORF70 chromosome 19 open reading frame 70 2.8904
DCPS decapping enzyme, scavenger 2.87927
FBL fibrillarin 2.81834
DPYD dihydropyrimidine dehydrogenase 2.8117
AFM afamin 2.79059
IL17RC interleukin 17 receptor C 2.78602
NELFE negative elongation factor complex member E 2.78432
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 2.76616
HACL1 2-hydroxyacyl-CoA lyase 1 2.64964
ESRP2 epithelial splicing regulatory protein 2 2.647
LRRC47 leucine rich repeat containing 47 2.63307
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa 2.629
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 2.60964
NAPRT nicotinate phosphoribosyltransferase 2.58845
APOE apolipoprotein E 2.57588
CNPY2 canopy FGF signaling regulator 2 2.56919
AHSG alpha-2-HS-glycoprotein 2.54975
CHCHD1 coiled-coil-helix-coiled-coil-helix domain containing 1 2.54863
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 2.49723
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 2.49261
SDHAF2 succinate dehydrogenase complex assembly factor 2 2.4925
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.47696
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 2.47294
PPDPF pancreatic progenitor cell differentiation and proliferation factor 2.45714
F10 coagulation factor X 2.44934
DDRGK1 DDRGK domain containing 1 2.44287
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.43675
IRF3 interferon regulatory factor 3 2.41957
UFSP1 UFM1-specific peptidase 1 (non-functional) 2.40414
DAPK3 death-associated protein kinase 3 2.40368
ETFB electron-transfer-flavoprotein, beta polypeptide 2.38979
DGAT1 diacylglycerol O-acyltransferase 1 2.38642
USP39 ubiquitin specific peptidase 39 2.37737
ARRDC2 arrestin domain containing 2 2.37341
MZT2A mitotic spindle organizing protein 2A 2.373
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 2.36485
TMX1 thioredoxin-related transmembrane protein 1 2.34819
MRPL34 mitochondrial ribosomal protein L34 2.3411
MFN1 mitofusin 1 2.33004
MTRF1 mitochondrial translational release factor 1 2.32129
RING1 ring finger protein 1 2.31218
EMC8 ER membrane protein complex subunit 8 2.30126
ALDOA aldolase A, fructose-bisphosphate 2.27276
MRPS34 mitochondrial ribosomal protein S34 2.25084
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 2.22885
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 2.22794
PEX16 peroxisomal biogenesis factor 16 2.20244
DDT D-dopachrome tautomerase 2.19654
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa 2.18279
TMEM53 transmembrane protein 53 2.17806
COMMD9 COMM domain containing 9 2.165
CERS2 ceramide synthase 2 2.16278
RBFA ribosome binding factor A (putative) 2.16253
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) 2.15305
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.12179
AAMP angio-associated, migratory cell protein 2.1211
MED6 mediator complex subunit 6 2.1196
C7ORF55 chromosome 7 open reading frame 55 2.11845
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 2.1163
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 2.10647
SEC14L2 SEC14-like 2 (S. cerevisiae) 2.1021
PLCL2 phospholipase C-like 2 2.09453
PECR peroxisomal trans-2-enoyl-CoA reductase 2.09137
GALT galactose-1-phosphate uridylyltransferase 2.09098
FLAD1 flavin adenine dinucleotide synthetase 1 2.0673
MRPS16 mitochondrial ribosomal protein S16 2.06288
CIAPIN1 cytokine induced apoptosis inhibitor 1 2.05416
NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa 2.05032
RAB17 RAB17, member RAS oncogene family 2.04795
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 2.0403
APOA1 apolipoprotein A-I 2.03871
SCARB2 scavenger receptor class B, member 2 2.03789
SH2B1 SH2B adaptor protein 1 2.03731
C18ORF32 chromosome 18 open reading frame 32 2.01818
C19ORF53 chromosome 19 open reading frame 53 1.99665
MTIF3 mitochondrial translational initiation factor 3 1.98373
ASGR1 asialoglycoprotein receptor 1 1.98064
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa 1.97976
TMEM205 transmembrane protein 205 1.97838
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 1.97664
EDRF1 erythroid differentiation regulatory factor 1 1.97287
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 1.97206
TMEM101 transmembrane protein 101 1.9714
BZW2 basic leucine zipper and W2 domains 2 1.96598
INPP5K inositol polyphosphate-5-phosphatase K 1.95724
CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10 1.95179
CTCF CCCTC-binding factor (zinc finger protein) 1.94366
CRELD1 cysteine-rich with EGF-like domains 1 1.93315
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 1.93073
UBL3 ubiquitin-like 3 1.91845
PDCL phosducin-like 1.91109
BBS7 Bardet-Biedl syndrome 7 1.90991
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 1.90282
PARD3B par-3 family cell polarity regulator beta 1.89938
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 1.89715
TRAP1 TNF receptor-associated protein 1 1.89417
MED27 mediator complex subunit 27 1.89344
EEF1B2 eukaryotic translation elongation factor 1 beta 2 1.89285
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) 1.88667
BRIX1 BRX1, biogenesis of ribosomes 1.88508
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 1.88075
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 1.88066
KARS lysyl-tRNA synthetase 1.86075
MOGS mannosyl-oligosaccharide glucosidase 1.8574
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 1.85556
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 1.8519
APOH apolipoprotein H (beta-2-glycoprotein I) 1.85045
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa 1.82463
EDA2R ectodysplasin A2 receptor 1.81598
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 1.81488
CRLS1 cardiolipin synthase 1 1.81347
MRPL12 mitochondrial ribosomal protein L12 1.8104
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37 1.80424
CDC16 cell division cycle 16 1.80034
MYBBP1A MYB binding protein (P160) 1a 1.79799
RAB21 RAB21, member RAS oncogene family 1.79796
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.79658
TMEM192 transmembrane protein 192 1.7898
RPL19 ribosomal protein L19 1.78872
SDF2 stromal cell-derived factor 2 1.7868
VAMP8 vesicle-associated membrane protein 8 1.78589
SH3YL1 SH3 and SYLF domain containing 1 1.78568
KIAA0020 KIAA0020 1.78037
FCF1 FCF1 rRNA-processing protein 1.77561
BCAS2 breast carcinoma amplified sequence 2 1.77417
VRK3 vaccinia related kinase 3 1.77113
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 1.76961
ALKBH7 alkB, alkylation repair homolog 7 (E. coli) 1.76735
CHMP3 charged multivesicular body protein 3 1.76691
MRPS21 mitochondrial ribosomal protein S21 1.76033
CHURC1 churchill domain containing 1 1.75267
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16 1.75085
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 1.74211
TMEM216 transmembrane protein 216 1.73966
SLC25A26 solute carrier family 25 (S-adenosylmethionine carrier), member 26 1.73732
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 1.73306
DENND2A DENN/MADD domain containing 2A 1.7223
EMC9 ER membrane protein complex subunit 9 1.71915
C17ORF67 chromosome 17 open reading frame 67 1.71431
TCN2 transcobalamin II 1.70961
ICT1 immature colon carcinoma transcript 1 1.70719
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 1.7002
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 1.6999
RPL35A ribosomal protein L35a 1.69809
EXD2 exonuclease 3'-5' domain containing 2 1.69689
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 1.69396
EDF1 endothelial differentiation-related factor 1 1.6896
CCDC58 coiled-coil domain containing 58 1.68815
SDCCAG3 serologically defined colon cancer antigen 3 1.68731
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1 1.6871
IPO13 importin 13 1.68646
PCID2 PCI domain containing 2 1.68212
OSER1 oxidative stress responsive serine-rich 1 1.68071
NR6A1 nuclear receptor subfamily 6, group A, member 1 1.67904
C16ORF89 chromosome 16 open reading frame 89 1.66667
RPL27 ribosomal protein L27 1.66485
VTI1B vesicle transport through interaction with t-SNAREs 1B 1.65918
SRSF9 serine/arginine-rich splicing factor 9 1.65828
DRG2 developmentally regulated GTP binding protein 2 1.65778
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 1.65413
COX4I1 cytochrome c oxidase subunit IV isoform 1 1.64988
NGDN neuroguidin, EIF4E binding protein 1.64944
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 1.64814
PITPNB phosphatidylinositol transfer protein, beta 1.6427
KYNU kynureninase 1.64076
DALRD3 DALR anticodon binding domain containing 3 1.64021
POLR2H polymerase (RNA) II (DNA directed) polypeptide H 1.63847
CNST consortin, connexin sorting protein 1.63837
TMEM125 transmembrane protein 125 1.63453
PRODH2 proline dehydrogenase (oxidase) 2 1.63289
ING4 inhibitor of growth family, member 4 1.62343
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 1.61963
C19ORF43 chromosome 19 open reading frame 43 1.61856
COG2 component of oligomeric golgi complex 2 1.61777
TRAPPC13 trafficking protein particle complex 13 1.61047
ABHD11 abhydrolase domain containing 11 1.60795
FABP6 fatty acid binding protein 6, ileal 1.60731
MRPL14 mitochondrial ribosomal protein L14 1.60633
KLF1 Kruppel-like factor 1 (erythroid) 1.60551
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 1.60322
SNX17 sorting nexin 17 1.59723
KATNA1 katanin p60 (ATPase containing) subunit A 1 1.59327
GID8 GID complex subunit 8 1.59321
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 1.58265
SQRDL sulfide quinone reductase-like (yeast) 1.58233
DROSHA drosha, ribonuclease type III 1.5807
MBL2 mannose-binding lectin (protein C) 2, soluble 1.57785
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) 1.57764
NIPBL Nipped-B homolog (Drosophila) 1.5744
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) 1.57206
METTL7B methyltransferase like 7B 1.5715
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 1.57058
CLK3 CDC-like kinase 3 1.56452
SCARF1 scavenger receptor class F, member 1 1.56012
ASCC1 activating signal cointegrator 1 complex subunit 1 1.55894
CFB complement factor B 1.55859
BIK BCL2-interacting killer (apoptosis-inducing) 1.55626
ZFAND2B zinc finger, AN1-type domain 2B 1.55099
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 1.54854
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 1.54498
COX15 cytochrome c oxidase assembly homolog 15 (yeast) 1.54239
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 1.54009
FAM167B family with sequence similarity 167, member B 1.53461
KDM6B lysine (K)-specific demethylase 6B 1.53344
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 1.5325
C9ORF156 chromosome 9 open reading frame 156 1.52709
HINT2 histidine triad nucleotide binding protein 2 1.525
PCED1A PC-esterase domain containing 1A 1.52203
SBDS Shwachman-Bodian-Diamond syndrome 1.52147
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae) 1.51976
SLC30A6 solute carrier family 30 (zinc transporter), member 6 1.51929
RPAIN RPA interacting protein 1.5175
ADCK5 aarF domain containing kinase 5 1.5166
GRPEL1 GrpE-like 1, mitochondrial (E. coli) 1.51578
COX14 COX14 cytochrome c oxidase assembly factor 1.51548
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 1.51311
NAT8B N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene) 1.51055
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 1.50898
TCAIM T cell activation inhibitor, mitochondrial 1.50882
ELAC2 elaC ribonuclease Z 2 1.50359
PTGES2 prostaglandin E synthase 2 1.49756
CLEC1A C-type lectin domain family 1, member A 1.49633
HIST1H4I histone cluster 1, H4i 1.49459
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 1.49432
TMEM256 transmembrane protein 256 1.4942
IFT20 intraflagellar transport 20 1.49098
TMBIM6 transmembrane BAX inhibitor motif containing 6 1.49076
STAMBP STAM binding protein 1.49069
RNF25 ring finger protein 25 1.48942
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) 1.48811
ABHD17C abhydrolase domain containing 17C 1.48769
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) 1.4869
SGK2 serum/glucocorticoid regulated kinase 2 1.4838
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 1.48264
GPR137 G protein-coupled receptor 137 1.48205
MPG N-methylpurine-DNA glycosylase 1.48117
RBM42 RNA binding motif protein 42 1.47806
C11ORF97 chromosome 11 open reading frame 97 1.47768
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 1.4751
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 1.47381
FKBP2 FK506 binding protein 2, 13kDa 1.4715
JOSD2 Josephin domain containing 2 1.47135
RPS15 ribosomal protein S15 1.46579
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 1.46255
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 1.46146
ACO2 aconitase 2, mitochondrial 1.45655
RHOT2 ras homolog family member T2 1.45542
MRPS7 mitochondrial ribosomal protein S7 1.4544
COX17 COX17 cytochrome c oxidase copper chaperone 1.45351
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 1.45127
PRPF38B pre-mRNA processing factor 38B 1.4495
NOSIP nitric oxide synthase interacting protein 1.4474
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 1.44313
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 1.44084
VMO1 vitelline membrane outer layer 1 homolog (chicken) 1.43788
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 1.4328
SPAG7 sperm associated antigen 7 1.43263
MRPL10 mitochondrial ribosomal protein L10 1.4305
RIOK1 RIO kinase 1 1.42995
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) 1.42849
BTD biotinidase 1.42662
RSL24D1 ribosomal L24 domain containing 1 1.42612
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 1.4257
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 1.42526
TFG TRK-fused gene 1.42485
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 1.42415
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 1.42365
F2 coagulation factor II (thrombin) 1.42123
TUFM Tu translation elongation factor, mitochondrial 1.42082
C8G complement component 8, gamma polypeptide 1.41873
STRA13 stimulated by retinoic acid 13 1.41534
MGLL monoglyceride lipase 1.41179
EIF3G eukaryotic translation initiation factor 3, subunit G 1.41022
PCIF1 PDX1 C-terminal inhibiting factor 1 1.40964
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit 1.40841
TGFBRAP1 transforming growth factor, beta receptor associated protein 1 1.40457
LINS lines homolog (Drosophila) 1.40381
IER3 immediate early response 3 1.40286
RUVBL1 RuvB-like AAA ATPase 1 1.40237
OSBPL11 oxysterol binding protein-like 11 1.40169
CCDC107 coiled-coil domain containing 107 1.39925
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 1.39741
TSSC4 tumor suppressing subtransferable candidate 4 1.39711
NR1H3 nuclear receptor subfamily 1, group H, member 3 1.39242
UBXN6 UBX domain protein 6 1.39089
AP3S2 adaptor-related protein complex 3, sigma 2 subunit 1.39079
RPL7L1 ribosomal protein L7-like 1 1.38671
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 1.38284
CEP89 centrosomal protein 89kDa 1.3813
GLYAT glycine-N-acyltransferase 1.37826
FGA fibrinogen alpha chain 1.37647
NSUN4 NOP2/Sun domain family, member 4 1.37633
PHKG2 phosphorylase kinase, gamma 2 (testis) 1.37447

decreased expression

Symbol Name Standardized Value
TMEM71 transmembrane protein 71 -5.06571
CDHR3 cadherin-related family member 3 -3.60976
ATXN10 ataxin 10 -3.36777
ACP6 acid phosphatase 6, lysophosphatidic -3.23506
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) -2.99004
PCYOX1 prenylcysteine oxidase 1 -2.97069
MFSD1 major facilitator superfamily domain containing 1 -2.96136
C3ORF67 chromosome 3 open reading frame 67 -2.94576
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta -2.93696
ANKRD49 ankyrin repeat domain 49 -2.93261
STYX serine/threonine/tyrosine interacting protein -2.88632
CUL4A cullin 4A -2.8171
TAGAP T-cell activation RhoGTPase activating protein -2.81362
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.80636
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) -2.79917
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase -2.79349
DHRS1 dehydrogenase/reductase (SDR family) member 1 -2.78532
COMMD3 COMM domain containing 3 -2.78114
GLT8D2 glycosyltransferase 8 domain containing 2 -2.70671
RAB4A RAB4A, member RAS oncogene family -2.61747
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 -2.60906
SRSF11 serine/arginine-rich splicing factor 11 -2.58801
NUDC nudC nuclear distribution protein -2.50007
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -2.49945
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) -2.49844
MOB1B MOB kinase activator 1B -2.49173
TMEM127 transmembrane protein 127 -2.48864
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa -2.44217
ORC6 origin recognition complex, subunit 6 -2.43701
TSSC1 tumor suppressing subtransferable candidate 1 -2.41154
BMP4 bone morphogenetic protein 4 -2.37125
BAHD1 bromo adjacent homology domain containing 1 -2.33511
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1 -2.33108
HYAL1 hyaluronoglucosaminidase 1 -2.31706
COL6A2 collagen, type VI, alpha 2 -2.28478
DENND5A DENN/MADD domain containing 5A -2.27783
COX5A cytochrome c oxidase subunit Va -2.26125
ALCAM activated leukocyte cell adhesion molecule -2.25055
STK11IP serine/threonine kinase 11 interacting protein -2.24339
MOSPD1 motile sperm domain containing 1 -2.24067
EMC3 ER membrane protein complex subunit 3 -2.22864
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 -2.22795
ZMAT3 zinc finger, matrin-type 3 -2.22418
MLF2 myeloid leukemia factor 2 -2.22206
LIPG lipase, endothelial -2.22039
TMEM110-MUSTN1 TMEM110-MUSTN1 readthrough -2.21611
RAB28 RAB28, member RAS oncogene family -2.20186
BHMT2 betaine--homocysteine S-methyltransferase 2 -2.19895
RPS4Y1 ribosomal protein S4, Y-linked 1 -2.18238
DCN decorin -2.15413
RABIF RAB interacting factor -2.14721
COL4A1 collagen, type IV, alpha 1 -2.12187
COL4A2 collagen, type IV, alpha 2 -2.11112
NRN1 neuritin 1 -2.06831
DBR1 debranching RNA lariats 1 -2.06755
CSK c-src tyrosine kinase -2.05431
CLU clusterin -2.05072
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) -2.04353
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) -2.02316
RBMS1 RNA binding motif, single stranded interacting protein 1 -2.02076
ATP7A ATPase, Cu++ transporting, alpha polypeptide -2.01116
C6ORF120 chromosome 6 open reading frame 120 -1.99566
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) -1.97925
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 -1.95423
SOX13 SRY (sex determining region Y)-box 13 -1.94537
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 -1.93966
RNF141 ring finger protein 141 -1.93761
EP300 E1A binding protein p300 -1.93446
FRK fyn-related Src family tyrosine kinase -1.93409
ACTB actin, beta -1.9115
EIF4H eukaryotic translation initiation factor 4H -1.90056
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa -1.89667
JKAMP JNK1/MAPK8-associated membrane protein -1.89502
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) -1.89362
TBCD tubulin folding cofactor D -1.87538
DIRC2 disrupted in renal carcinoma 2 -1.87495
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -1.8711
IPO5 importin 5 -1.867
F2R coagulation factor II (thrombin) receptor -1.84783
TFDP1 transcription factor Dp-1 -1.84488
THUMPD1 THUMP domain containing 1 -1.83332
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like -1.82887
APP amyloid beta (A4) precursor protein -1.82813
TBC1D2B TBC1 domain family, member 2B -1.81216
MAN1B1 mannosidase, alpha, class 1B, member 1 -1.8037
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -1.79698
RNF6 ring finger protein (C3H2C3 type) 6 -1.79627
PPAP2C phosphatidic acid phosphatase type 2C -1.79365
ZNF219 zinc finger protein 219 -1.79207
ZBTB24 zinc finger and BTB domain containing 24 -1.79177
PRDX3 peroxiredoxin 3 -1.78941
RAB11B RAB11B, member RAS oncogene family -1.78599
GOLIM4 golgi integral membrane protein 4 -1.78308
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -1.77653
RRAS related RAS viral (r-ras) oncogene homolog -1.76032
OSTM1 osteopetrosis associated transmembrane protein 1 -1.75619
EI24 etoposide induced 2.4 -1.74644
PDGFA platelet-derived growth factor alpha polypeptide -1.74436
GSS glutathione synthetase -1.73111
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 -1.72917
MRPL18 mitochondrial ribosomal protein L18 -1.72871
MAML1 mastermind-like 1 (Drosophila) -1.71471
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) -1.70622
ZFAND2A zinc finger, AN1-type domain 2A -1.69923
FCHO2 FCH domain only 2 -1.69471
GUSB glucuronidase, beta -1.69111
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -1.6869
MMP15 matrix metallopeptidase 15 (membrane-inserted) -1.68116
MSRB2 methionine sulfoxide reductase B2 -1.67941
PROSER1 proline and serine rich 1 -1.67854
CCKAR cholecystokinin A receptor -1.67802
TERF2 telomeric repeat binding factor 2 -1.67693
SETD6 SET domain containing 6 -1.6763
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -1.67521
BCL2L13 BCL2-like 13 (apoptosis facilitator) -1.67242
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial) -1.66721
PXK PX domain containing serine/threonine kinase -1.66303
NMT1 N-myristoyltransferase 1 -1.66301
CSTB cystatin B (stefin B) -1.65966
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.65966
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 -1.65936
PPCS phosphopantothenoylcysteine synthetase -1.65731
GCC2 GRIP and coiled-coil domain containing 2 -1.65342
ERRFI1 ERBB receptor feedback inhibitor 1 -1.65064
CASP2 caspase 2, apoptosis-related cysteine peptidase -1.64929
FBF1 Fas (TNFRSF6) binding factor 1 -1.64907
QPRT quinolinate phosphoribosyltransferase -1.63993
REEP3 receptor accessory protein 3 -1.63948
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -1.62808
MICU2 mitochondrial calcium uptake 2 -1.62311
CD63 CD63 molecule -1.61974
ENG endoglin -1.61657
SCAMP3 secretory carrier membrane protein 3 -1.61524
PKP2 plakophilin 2 -1.61522
CASP8 caspase 8, apoptosis-related cysteine peptidase -1.61443
LMO4 LIM domain only 4 -1.61016
MAN2B1 mannosidase, alpha, class 2B, member 1 -1.606
TRAM1 translocation associated membrane protein 1 -1.6033
RNF44 ring finger protein 44 -1.60068
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -1.59932
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -1.59363
FBXL14 F-box and leucine-rich repeat protein 14 -1.59206
XYLT2 xylosyltransferase II -1.58766
TMEM9 transmembrane protein 9 -1.5736
ATXN7L2 ataxin 7-like 2 -1.57118
HP haptoglobin -1.57113
FTH1 ferritin, heavy polypeptide 1 -1.5708
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -1.56901
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 -1.56398
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -1.56154
STRBP spermatid perinuclear RNA binding protein -1.55312
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -1.55229
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 -1.54752
UBL5 ubiquitin-like 5 -1.53863
ISCU iron-sulfur cluster assembly enzyme -1.53506
PUM2 pumilio RNA-binding family member 2 -1.53272
COPB2 coatomer protein complex, subunit beta 2 (beta prime) -1.53168
ZDHHC21 zinc finger, DHHC-type containing 21 -1.52876
RPL10 ribosomal protein L10 -1.52846
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1 -1.52744
USF1 upstream transcription factor 1 -1.52367
RAB24 RAB24, member RAS oncogene family -1.52051
PTH parathyroid hormone -1.51973
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) -1.5108
TMEM19 transmembrane protein 19 -1.51036
SFXN1 sideroflexin 1 -1.50993
DRAM2 DNA-damage regulated autophagy modulator 2 -1.507
ARMCX2 armadillo repeat containing, X-linked 2 -1.50536
PSEN1 presenilin 1 -1.49881
MSH6 mutS homolog 6 -1.49755
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha -1.49704
THUMPD3 THUMP domain containing 3 -1.49656
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -1.48843
NAP1L1 nucleosome assembly protein 1-like 1 -1.48556
SPP2 secreted phosphoprotein 2, 24kDa -1.48472
CCAR1 cell division cycle and apoptosis regulator 1 -1.48212
TRIM32 tripartite motif containing 32 -1.48197
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -1.48091
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase -1.46751
LARGE like-glycosyltransferase -1.46526
PRKCD protein kinase C, delta -1.46436
PRKDC protein kinase, DNA-activated, catalytic polypeptide -1.45897
FAM179A family with sequence similarity 179, member A -1.45389
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -1.4514
RNASET2 ribonuclease T2 -1.45101
MCOLN1 mucolipin 1 -1.44785
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta -1.44761
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -1.44585
SPTBN2 spectrin, beta, non-erythrocytic 2 -1.44232
TTC33 tetratricopeptide repeat domain 33 -1.44163
ALDOB aldolase B, fructose-bisphosphate -1.43464
SAV1 salvador family WW domain containing protein 1 -1.43445
GAK cyclin G associated kinase -1.43373
MPP1 membrane protein, palmitoylated 1, 55kDa -1.42972
COL1A1 collagen, type I, alpha 1 -1.42702
RBM4B RNA binding motif protein 4B -1.42657
ACOX2 acyl-CoA oxidase 2, branched chain -1.41662
PARP3 poly (ADP-ribose) polymerase family, member 3 -1.41457
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 -1.41128
EPRS glutamyl-prolyl-tRNA synthetase -1.40845
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -1.40752
RAB6A RAB6A, member RAS oncogene family -1.40725
FAM126B family with sequence similarity 126, member B -1.40501
SLC46A1 solute carrier family 46 (folate transporter), member 1 -1.40488
TIMP2 TIMP metallopeptidase inhibitor 2 -1.4048
CLPTM1L CLPTM1-like -1.40325
CADPS2 Ca++-dependent secretion activator 2 -1.40176
TYK2 tyrosine kinase 2 -1.39915
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -1.39744
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 -1.39505
MYADM myeloid-associated differentiation marker -1.39454
C14ORF166 chromosome 14 open reading frame 166 -1.39356
NUBP1 nucleotide binding protein 1 -1.39255
AHDC1 AT hook, DNA binding motif, containing 1 -1.38899
PYGL phosphorylase, glycogen, liver -1.38483
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -1.38271
SLC7A4 solute carrier family 7, member 4 -1.38122
MBNL2 muscleblind-like splicing regulator 2 -1.38024
LIMD1 LIM domains containing 1 -1.3767
SLC39A11 solute carrier family 39, member 11 -1.37291
CST3 cystatin C -1.37197
MANBA mannosidase, beta A, lysosomal -1.36965
UBE2B ubiquitin-conjugating enzyme E2B -1.36474
MIEF1 mitochondrial elongation factor 1 -1.36163
SNAP23 synaptosomal-associated protein, 23kDa -1.36157
ANGEL2 angel homolog 2 (Drosophila) -1.3609
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 -1.36058
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -1.36005
PRR15 proline rich 15 -1.35785
ORAI3 ORAI calcium release-activated calcium modulator 3 -1.35417
REP15 RAB15 effector protein -1.35314
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C -1.34979
SYPL1 synaptophysin-like 1 -1.34909
RPL23 ribosomal protein L23 -1.34641
APOA2 apolipoprotein A-II -1.34632
CSNK1D casein kinase 1, delta -1.34573
PLCE1 phospholipase C, epsilon 1 -1.34477
APEH acylaminoacyl-peptide hydrolase -1.34282
WBP5 WW domain binding protein 5 -1.34137
MAPRE1 microtubule-associated protein, RP/EB family, member 1 -1.33777
C1ORF86 chromosome 1 open reading frame 86 -1.33673
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) -1.33304
PRKACA protein kinase, cAMP-dependent, catalytic, alpha -1.33286
PHKA2 phosphorylase kinase, alpha 2 (liver) -1.33048
IL17RB interleukin 17 receptor B -1.326
ABHD17A abhydrolase domain containing 17A -1.32593
SSRP1 structure specific recognition protein 1 -1.32472
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) -1.32358
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B -1.32168
OSMR oncostatin M receptor -1.32053
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -1.31618
PARL presenilin associated, rhomboid-like -1.31394
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain -1.31295
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 -1.31162
TCF21 transcription factor 21 -1.31089
RAB5C RAB5C, member RAS oncogene family -1.3068
NR1H2 nuclear receptor subfamily 1, group H, member 2 -1.30675
MYLK myosin light chain kinase -1.30571
MRPL16 mitochondrial ribosomal protein L16 -1.30504
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) -1.30439
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -1.30371
EXOC2 exocyst complex component 2 -1.30212
FAM76B family with sequence similarity 76, member B -1.29977
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa -1.29341
ZNF175 zinc finger protein 175 -1.29285
EXOC4 exocyst complex component 4 -1.28764
AMBP alpha-1-microglobulin/bikunin precursor -1.28705
SIAE sialic acid acetylesterase -1.28417
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -1.28345
TMEM55A transmembrane protein 55A -1.28143
KLHDC2 kelch domain containing 2 -1.28035
PDS5B PDS5 cohesin associated factor B -1.27277
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric -1.27124
GCA grancalcin, EF-hand calcium binding protein -1.26796
RGS7BP regulator of G-protein signaling 7 binding protein -1.26624
ARL16 ADP-ribosylation factor-like 16 -1.26607
SNTA1 syntrophin, alpha 1 -1.26571
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -1.26533
C17ORF85 chromosome 17 open reading frame 85 -1.26319
ACTN4 actinin, alpha 4 -1.26145
TRAPPC1 trafficking protein particle complex 1 -1.26083
IRF2 interferon regulatory factor 2 -1.25968
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 -1.25956
RC3H1 ring finger and CCCH-type domains 1 -1.25413
DPP4 dipeptidyl-peptidase 4 -1.25375
RPS6 ribosomal protein S6 -1.25372
ZFYVE21 zinc finger, FYVE domain containing 21 -1.25238
RPS7 ribosomal protein S7 -1.25103
OSBPL9 oxysterol binding protein-like 9 -1.24421
OSBPL2 oxysterol binding protein-like 2 -1.24372
ADGRL4 adhesion G protein-coupled receptor L4 -1.24235
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -1.24047
RPL36AL ribosomal protein L36a-like -1.23853
CDR2 cerebellar degeneration-related protein 2, 62kDa -1.23048
MIS18A MIS18 kinetochore protein A -1.2302
EMCN endomucin -1.22966
CLEC4E C-type lectin domain family 4, member E -1.2291
NID1 nidogen 1 -1.22568
TRIP12 thyroid hormone receptor interactor 12 -1.22461
HEXA hexosaminidase A (alpha polypeptide) -1.22068