MET_knockout_260_GSE25583 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE25583
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Genes

600 genes differentially expressed following the MET_knockout_260_GSE25583 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 3.17554
PRELP proline/arginine-rich end leucine-rich repeat protein 3.07423
IKBIP IKBKB interacting protein 2.87024
S100A10 S100 calcium binding protein A10 2.86552
PLVAP plasmalemma vesicle associated protein 2.85
IL6ST interleukin 6 signal transducer 2.83065
LEPROT leptin receptor overlapping transcript 2.80865
CHMP5 charged multivesicular body protein 5 2.78487
AP1AR adaptor-related protein complex 1 associated regulatory protein 2.69643
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) 2.69558
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 2.6888
PMPCB peptidase (mitochondrial processing) beta 2.67849
ACP6 acid phosphatase 6, lysophosphatidic 2.67305
COPG1 coatomer protein complex, subunit gamma 1 2.65806
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 2.64194
OTUD6B OTU domain containing 6B 2.63422
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase 2.62946
ABHD17C abhydrolase domain containing 17C 2.62383
EMC7 ER membrane protein complex subunit 7 2.62241
CSRP2 cysteine and glycine-rich protein 2 2.62105
EIF4A1 eukaryotic translation initiation factor 4A1 2.58747
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 2.52647
PDE8A phosphodiesterase 8A 2.49599
R3HDM2 R3H domain containing 2 2.49469
STEAP2 STEAP family member 2, metalloreductase 2.44599
RAB28 RAB28, member RAS oncogene family 2.44228
PHAX phosphorylated adaptor for RNA export 2.43213
CD53 CD53 molecule 2.42886
EXOSC6 exosome component 6 2.40107
CLIP1 CAP-GLY domain containing linker protein 1 2.39982
PLS3 plastin 3 2.37311
ACER3 alkaline ceramidase 3 2.37108
RPL5 ribosomal protein L5 2.34484
RHOB ras homolog family member B 2.34258
C12ORF57 chromosome 12 open reading frame 57 2.33465
RPUSD4 RNA pseudouridylate synthase domain containing 4 2.29641
ADAM9 ADAM metallopeptidase domain 9 2.29501
XPC xeroderma pigmentosum, complementation group C 2.29228
TUBB4B tubulin, beta 4B class IVb 2.26498
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 2.24215
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 2.23463
MRPL52 mitochondrial ribosomal protein L52 2.23092
GHITM growth hormone inducible transmembrane protein 2.22136
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 2.20849
VBP1 von Hippel-Lindau binding protein 1 2.19996
DOLK dolichol kinase 2.19659
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 2.18686
PFDN2 prefoldin subunit 2 2.18678
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 2.18158
SRSF9 serine/arginine-rich splicing factor 9 2.17876
NTPCR nucleoside-triphosphatase, cancer-related 2.17249
FTH1 ferritin, heavy polypeptide 1 2.16991
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 2.15862
HNRNPL heterogeneous nuclear ribonucleoprotein L 2.15518
SQRDL sulfide quinone reductase-like (yeast) 2.14238
EIF4A2 eukaryotic translation initiation factor 4A2 2.13214
MIF4GD MIF4G domain containing 2.11843
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 2.11807
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.10578
SELK selenoprotein K 2.10075
NDFIP2 Nedd4 family interacting protein 2 2.09522
KPNA1 karyopherin alpha 1 (importin alpha 5) 2.08701
CD164 CD164 molecule, sialomucin 2.08594
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase 2.0855
PDLIM1 PDZ and LIM domain 1 2.08324
GAA glucosidase, alpha; acid 2.07921
TGFBI transforming growth factor, beta-induced, 68kDa 2.07022
KRT8 keratin 8, type II 2.06999
CS citrate synthase 2.05701
HIST1H3B histone cluster 1, H3b 2.04914
RABGGTB Rab geranylgeranyltransferase, beta subunit 2.04668
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae) 2.0313
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.02215
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) 2.01266
FAM107B family with sequence similarity 107, member B 1.99075
SGPL1 sphingosine-1-phosphate lyase 1 1.98843
PRMT3 protein arginine methyltransferase 3 1.98325
ENG endoglin 1.97517
PPIF peptidylprolyl isomerase F 1.95118
TRIM41 tripartite motif containing 41 1.94436
TBC1D25 TBC1 domain family, member 25 1.94155
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 1.93037
F2 coagulation factor II (thrombin) 1.92436
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 1.9196
LUM lumican 1.91774
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 1.91419
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 1.91271
ATL2 atlastin GTPase 2 1.89948
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.89854
NEO1 neogenin 1 1.89103
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase 1.88852
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 1.88155
FCF1 FCF1 rRNA-processing protein 1.86445
NNMT nicotinamide N-methyltransferase 1.84727
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 1.84127
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 1.83516
COMMD9 COMM domain containing 9 1.82192
MAPK11 mitogen-activated protein kinase 11 1.80566
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 1.80366
APOH apolipoprotein H (beta-2-glycoprotein I) 1.80327
SPAG9 sperm associated antigen 9 1.80229
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.79756
ICMT isoprenylcysteine carboxyl methyltransferase 1.79487
TUBB6 tubulin, beta 6 class V 1.78322
KPNB1 karyopherin (importin) beta 1 1.77989
CKAP5 cytoskeleton associated protein 5 1.77554
DAZAP2 DAZ associated protein 2 1.7662
LAMP1 lysosomal-associated membrane protein 1 1.76043
OAZ1 ornithine decarboxylase antizyme 1 1.75907
COL4A2 collagen, type IV, alpha 2 1.75542
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 1.74825
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 1.73858
SEC24B SEC24 family member B 1.73586
SLC30A6 solute carrier family 30 (zinc transporter), member 6 1.72713
ILKAP integrin-linked kinase-associated serine/threonine phosphatase 1.72572
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 1.72176
TMEM11 transmembrane protein 11 1.72035
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 1.71931
CCT8 chaperonin containing TCP1, subunit 8 (theta) 1.71615
WBP4 WW domain binding protein 4 1.71196
RHOC ras homolog family member C 1.70538
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae) 1.70133
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 1.68964
MAN2A1 mannosidase, alpha, class 2A, member 1 1.67224
RPL7L1 ribosomal protein L7-like 1 1.67047
BROX BRO1 domain and CAAX motif containing 1.66906
RER1 retention in endoplasmic reticulum sorting receptor 1 1.66428
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 1.66363
RPL35A ribosomal protein L35a 1.66163
SEC11C SEC11 homolog C (S. cerevisiae) 1.66069
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 1.66021
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 1.65711
YLPM1 YLP motif containing 1 1.65206
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.65093
COX14 COX14 cytochrome c oxidase assembly factor 1.64592
F8 coagulation factor VIII, procoagulant component 1.64551
RIPK4 receptor-interacting serine-threonine kinase 4 1.64287
IL10RB interleukin 10 receptor, beta 1.62671
CTSB cathepsin B 1.62245
CLDN2 claudin 2 1.62126
BTBD1 BTB (POZ) domain containing 1 1.62044
FBL fibrillarin 1.61841
TRIP6 thyroid hormone receptor interactor 6 1.61788
ZFAND3 zinc finger, AN1-type domain 3 1.6178
RAB5C RAB5C, member RAS oncogene family 1.60932
MORF4L2 mortality factor 4 like 2 1.60829
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa 1.60187
CD81 CD81 molecule 1.59684
STK39 serine threonine kinase 39 1.59615
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 1.59456
RPS10 ribosomal protein S10 1.59237
SPAG7 sperm associated antigen 7 1.59211
KLF2 Kruppel-like factor 2 1.58941
COG2 component of oligomeric golgi complex 2 1.5809
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 1.57768
DYNLT3 dynein, light chain, Tctex-type 3 1.57257
OSMR oncostatin M receptor 1.56613
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 1.56493
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.56222
NDRG3 NDRG family member 3 1.56022
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.55863
MARS2 methionyl-tRNA synthetase 2, mitochondrial 1.54344
RPS9 ribosomal protein S9 1.5411
RERG RAS-like, estrogen-regulated, growth inhibitor 1.53578
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) 1.52966
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum) 1.52322
TRAPPC4 trafficking protein particle complex 4 1.52247
CYTH3 cytohesin 3 1.52183
TSEN15 TSEN15 tRNA splicing endonuclease subunit 1.52132
TMEM65 transmembrane protein 65 1.52043
SEC24C SEC24 family member C 1.51981
CHMP4B charged multivesicular body protein 4B 1.51551
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 1.51097
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 1.50534
SMIM12 small integral membrane protein 12 1.50517
KATNA1 katanin p60 (ATPase containing) subunit A 1 1.50485
TMEM259 transmembrane protein 259 1.50256
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 1.50079
NCBP1 nuclear cap binding protein subunit 1, 80kDa 1.49815
EMG1 EMG1 N1-specific pseudouridine methyltransferase 1.49615
TDO2 tryptophan 2,3-dioxygenase 1.49372
DENND1A DENN/MADD domain containing 1A 1.49295
INHBB inhibin, beta B 1.49204
SAT1 spermidine/spermine N1-acetyltransferase 1 1.48843
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.48641
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.47728
DCAF13 DDB1 and CUL4 associated factor 13 1.47623
KIAA0232 KIAA0232 1.47368
EMILIN1 elastin microfibril interfacer 1 1.45773
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 1.45763
MINA MYC induced nuclear antigen 1.45671
BLCAP bladder cancer associated protein 1.45639
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 1.45598
KAT7 K(lysine) acetyltransferase 7 1.44979
OSER1 oxidative stress responsive serine-rich 1 1.44826
ALS2 amyotrophic lateral sclerosis 2 (juvenile) 1.44813
MDFIC MyoD family inhibitor domain containing 1.4409
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 1.43931
APMAP adipocyte plasma membrane associated protein 1.43841
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 1.43814
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 1.4229
MXRA8 matrix-remodelling associated 8 1.42088
PPP6R3 protein phosphatase 6, regulatory subunit 3 1.41928
EVI5 ecotropic viral integration site 5 1.41624
OSBPL8 oxysterol binding protein-like 8 1.41429
HDAC2 histone deacetylase 2 1.4136
RBP2 retinol binding protein 2, cellular 1.41256
NPM3 nucleophosmin/nucleoplasmin 3 1.40932
CDC42SE1 CDC42 small effector 1 1.40545
ARL8A ADP-ribosylation factor-like 8A 1.40474
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 1.40124
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 1.39782
C1QA complement component 1, q subcomponent, A chain 1.39556
AKAP12 A kinase (PRKA) anchor protein 12 1.38771
HAT1 histone acetyltransferase 1 1.38576
TEX2 testis expressed 2 1.38451
RPL22 ribosomal protein L22 1.37932
EIF4H eukaryotic translation initiation factor 4H 1.37814
PGAM5 phosphoglycerate mutase family member 5 1.37513
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) 1.37461
ANKRD39 ankyrin repeat domain 39 1.37335
TMEM199 transmembrane protein 199 1.37061
FCHO2 FCH domain only 2 1.37007
TINAGL1 tubulointerstitial nephritis antigen-like 1 1.36041
ZNRD1 zinc ribbon domain containing 1 1.35847
RAB8B RAB8B, member RAS oncogene family 1.35531
HOOK2 hook microtubule-tethering protein 2 1.35339
C5ORF15 chromosome 5 open reading frame 15 1.35191
KPNA3 karyopherin alpha 3 (importin alpha 4) 1.349
KTI12 KTI12 homolog, chromatin associated (S. cerevisiae) 1.34826
RAI14 retinoic acid induced 14 1.34657
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 1.34007
LAMC1 laminin, gamma 1 (formerly LAMB2) 1.33637
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 1.33366
IST1 increased sodium tolerance 1 homolog (yeast) 1.32995
ING4 inhibitor of growth family, member 4 1.32911
DTNBP1 dystrobrevin binding protein 1 1.32551
BZW1 basic leucine zipper and W2 domains 1 1.31956
PLD3 phospholipase D family, member 3 1.31144
RECK reversion-inducing-cysteine-rich protein with kazal motifs 1.31079
CLMN calmin (calponin-like, transmembrane) 1.31045
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 1.30638
TMEM43 transmembrane protein 43 1.30517
C9ORF40 chromosome 9 open reading frame 40 1.30502
LRP6 low density lipoprotein receptor-related protein 6 1.30432
KIAA0355 KIAA0355 1.30255
KLHL18 kelch-like family member 18 1.29682
DLD dihydrolipoamide dehydrogenase 1.29532
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 1.29254
SAMD4B sterile alpha motif domain containing 4B 1.28826
MAP2K4 mitogen-activated protein kinase kinase 4 1.28762
MRPL20 mitochondrial ribosomal protein L20 1.28511
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 1.2836
HLA-DOA major histocompatibility complex, class II, DO alpha 1.28268
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 1.2824
METAP1 methionyl aminopeptidase 1 1.28046
FHL1 four and a half LIM domains 1 1.27994
WFDC1 WAP four-disulfide core domain 1 1.27733
LIMA1 LIM domain and actin binding 1 1.27629
THBD thrombomodulin 1.27541
PIAS1 protein inhibitor of activated STAT, 1 1.27345
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 1.2727
SRPR signal recognition particle receptor (docking protein) 1.27002
THUMPD1 THUMP domain containing 1 1.26626
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 1.26523
SNIP1 Smad nuclear interacting protein 1 1.26479
NMD3 NMD3 ribosome export adaptor 1.26115
PFN2 profilin 2 1.25715
HPS3 Hermansky-Pudlak syndrome 3 1.25645
TTYH2 tweety family member 2 1.25615
SLC30A1 solute carrier family 30 (zinc transporter), member 1 1.25033
FGFR1OP2 FGFR1 oncogene partner 2 1.2466
EPS8L2 EPS8-like 2 1.24601
PDK4 pyruvate dehydrogenase kinase, isozyme 4 1.2453
NCEH1 neutral cholesterol ester hydrolase 1 1.24004
DUSP1 dual specificity phosphatase 1 1.2391
UBAP1 ubiquitin associated protein 1 1.23554
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.23512
USP3 ubiquitin specific peptidase 3 1.23203
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit 1.22803
SF3A1 splicing factor 3a, subunit 1, 120kDa 1.22659
EPB41 erythrocyte membrane protein band 4.1 1.22467
CTSS cathepsin S 1.22426
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 1.22137
E2F3 E2F transcription factor 3 1.22131
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 1.21856
FTSJ3 FtsJ homolog 3 (E. coli) 1.21815
PCGF1 polycomb group ring finger 1 1.21662
ENC1 ectodermal-neural cortex 1 (with BTB domain) 1.21617
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 1.21206
TFIP11 tuftelin interacting protein 11 1.20101
DIAPH1 diaphanous-related formin 1 1.20083
SLC38A4 solute carrier family 38, member 4 1.19996
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 1.19631
ADGRE5 adhesion G protein-coupled receptor E5 1.19261
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 1.19147
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 1.18928
H2AFX H2A histone family, member X 1.18779
MED4 mediator complex subunit 4 1.18627
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 1.18561

decreased expression

Symbol Name Standardized Value
FAM160A1 family with sequence similarity 160, member A1 -4.93261
RNASE9 ribonuclease, RNase A family, 9 (non-active) -4.85069
IFITM3 interferon induced transmembrane protein 3 -3.54837
LRP10 low density lipoprotein receptor-related protein 10 -3.22407
CNKSR2 connector enhancer of kinase suppressor of Ras 2 -3.17191
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide -2.92833
LAX1 lymphocyte transmembrane adaptor 1 -2.90942
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial -2.90033
CCR6 chemokine (C-C motif) receptor 6 -2.82714
TRIM8 tripartite motif containing 8 -2.73326
CENPB centromere protein B, 80kDa -2.71921
RAB2A RAB2A, member RAS oncogene family -2.71856
STK19 serine/threonine kinase 19 -2.68283
MFAP5 microfibrillar associated protein 5 -2.65839
CEP295 centrosomal protein 295kDa -2.65633
F11 coagulation factor XI -2.63753
STARD5 StAR-related lipid transfer (START) domain containing 5 -2.50582
NR4A1 nuclear receptor subfamily 4, group A, member 1 -2.50363
CD274 CD274 molecule -2.49402
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 -2.49145
ARHGAP25 Rho GTPase activating protein 25 -2.48577
SIPA1L1 signal-induced proliferation-associated 1 like 1 -2.46483
APOC4 apolipoprotein C-IV -2.44639
ACTR5 ARP5 actin-related protein 5 homolog (yeast) -2.44133
OLFML1 olfactomedin-like 1 -2.43113
C16ORF58 chromosome 16 open reading frame 58 -2.42927
THBS4 thrombospondin 4 -2.42522
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 -2.42477
NELFB negative elongation factor complex member B -2.416
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.38674
TLCD1 TLC domain containing 1 -2.31581
WDR24 WD repeat domain 24 -2.28934
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D -2.24821
C14ORF1 chromosome 14 open reading frame 1 -2.24498
LTB lymphotoxin beta (TNF superfamily, member 3) -2.24418
GCGR glucagon receptor -2.21233
LY86 lymphocyte antigen 86 -2.20463
ZNF521 zinc finger protein 521 -2.20262
DDAH1 dimethylarginine dimethylaminohydrolase 1 -2.19734
TUBG1 tubulin, gamma 1 -2.18197
ANAPC16 anaphase promoting complex subunit 16 -2.17579
TALDO1 transaldolase 1 -2.16735
ARL16 ADP-ribosylation factor-like 16 -2.14866
NLRC5 NLR family, CARD domain containing 5 -2.11734
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.10763
MRPS7 mitochondrial ribosomal protein S7 -2.06982
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -2.06821
GORASP1 golgi reassembly stacking protein 1, 65kDa -2.06578
UNC13B unc-13 homolog B (C. elegans) -2.06546
ACOX2 acyl-CoA oxidase 2, branched chain -2.06263
TANGO2 transport and golgi organization 2 homolog (Drosophila) -2.05843
PVALB parvalbumin -2.05331
RAB21 RAB21, member RAS oncogene family -2.04793
ACBD6 acyl-CoA binding domain containing 6 -2.04238
GFM2 G elongation factor, mitochondrial 2 -2.04178
ETFB electron-transfer-flavoprotein, beta polypeptide -2.03516
CDO1 cysteine dioxygenase type 1 -2.01071
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C -1.99216
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 -1.98447
TOPBP1 topoisomerase (DNA) II binding protein 1 -1.97923
STX5 syntaxin 5 -1.97485
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -1.96501
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa -1.95261
PARK7 parkinson protein 7 -1.94805
ADGRF2 adhesion G protein-coupled receptor F2 -1.93359
IRAK3 interleukin-1 receptor-associated kinase 3 -1.92164
ECHDC3 enoyl CoA hydratase domain containing 3 -1.91655
IVD isovaleryl-CoA dehydrogenase -1.89868
FKBP8 FK506 binding protein 8, 38kDa -1.89735
TUFM Tu translation elongation factor, mitochondrial -1.89429
PTTG1IP pituitary tumor-transforming 1 interacting protein -1.88588
MMP10 matrix metallopeptidase 10 -1.8709
HGS hepatocyte growth factor-regulated tyrosine kinase substrate -1.86836
AP4B1 adaptor-related protein complex 4, beta 1 subunit -1.86644
MED16 mediator complex subunit 16 -1.86016
SLC35B1 solute carrier family 35, member B1 -1.84885
NAT9 N-acetyltransferase 9 (GCN5-related, putative) -1.84371
SELL selectin L -1.83473
COPA coatomer protein complex, subunit alpha -1.82417
FREM1 FRAS1 related extracellular matrix 1 -1.82062
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 -1.81129
KAT8 K(lysine) acetyltransferase 8 -1.80892
CELA1 chymotrypsin-like elastase family, member 1 -1.80418
GSTZ1 glutathione S-transferase zeta 1 -1.80115
GJB1 gap junction protein, beta 1, 32kDa -1.79236
DIABLO diablo, IAP-binding mitochondrial protein -1.7916
TMPRSS2 transmembrane protease, serine 2 -1.78522
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -1.78396
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 -1.78237
FBXO31 F-box protein 31 -1.76948
RAB4A RAB4A, member RAS oncogene family -1.76842
SAP30L SAP30-like -1.75332
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -1.74531
FGA fibrinogen alpha chain -1.73474
SYBU syntabulin (syntaxin-interacting) -1.7225
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -1.71809
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 -1.71676
KIAA0141 KIAA0141 -1.71227
ADCK5 aarF domain containing kinase 5 -1.70943
ATG5 autophagy related 5 -1.7086
TCF25 transcription factor 25 (basic helix-loop-helix) -1.70845
HGFAC HGF activator -1.70804
GATA5 GATA binding protein 5 -1.70261
AIM1 absent in melanoma 1 -1.69259
NPEPL1 aminopeptidase-like 1 -1.69022
RP9 retinitis pigmentosa 9 (autosomal dominant) -1.67569
PEX26 peroxisomal biogenesis factor 26 -1.67452
SLC1A7 solute carrier family 1 (glutamate transporter), member 7 -1.66942
MTTP microsomal triglyceride transfer protein -1.6682
DRG2 developmentally regulated GTP binding protein 2 -1.66651
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -1.66522
RPN2 ribophorin II -1.65996
FAM63A family with sequence similarity 63, member A -1.6567
NRD1 nardilysin (N-arginine dibasic convertase) -1.6505
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein -1.64027
PSEN2 presenilin 2 -1.62885
MRPL14 mitochondrial ribosomal protein L14 -1.62882
NAPB N-ethylmaleimide-sensitive factor attachment protein, beta -1.62563
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -1.62458
RSRC1 arginine/serine-rich coiled-coil 1 -1.62021
ARAF A-Raf proto-oncogene, serine/threonine kinase -1.6178
ARF1 ADP-ribosylation factor 1 -1.61409
BMP1 bone morphogenetic protein 1 -1.61153
CD276 CD276 molecule -1.61109
RAB31 RAB31, member RAS oncogene family -1.60175
ZNF665 zinc finger protein 665 -1.59341
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) -1.58963
NMRK1 nicotinamide riboside kinase 1 -1.58945
C11ORF31 chromosome 11 open reading frame 31 -1.58914
PARVA parvin, alpha -1.58846
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -1.58058
ZBTB5 zinc finger and BTB domain containing 5 -1.57931
ESYT1 extended synaptotagmin-like protein 1 -1.57189
RAP2B RAP2B, member of RAS oncogene family -1.57173
BABAM1 BRISC and BRCA1 A complex member 1 -1.56968
TMEM147 transmembrane protein 147 -1.5645
GRHPR glyoxylate reductase/hydroxypyruvate reductase -1.56307
ACAA1 acetyl-CoA acyltransferase 1 -1.55776
WDR83OS WD repeat domain 83 opposite strand -1.55244
PPA1 pyrophosphatase (inorganic) 1 -1.55147
RYK receptor-like tyrosine kinase -1.54965
BOLA1 bolA family member 1 -1.54889
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -1.54888
RAB12 RAB12, member RAS oncogene family -1.5463
ETV3 ets variant 3 -1.54515
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -1.54067
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -1.52402
TXN2 thioredoxin 2 -1.51838
DOCK4 dedicator of cytokinesis 4 -1.51728
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -1.51613
GOLGA3 golgin A3 -1.51122
KLHL1 kelch-like family member 1 -1.50866
FAM173B family with sequence similarity 173, member B -1.49578
NANS N-acetylneuraminic acid synthase -1.49224
ZNF394 zinc finger protein 394 -1.49099
CINP cyclin-dependent kinase 2 interacting protein -1.48812
BCO2 beta-carotene oxygenase 2 -1.48553
RNF123 ring finger protein 123 -1.47861
KRAS Kirsten rat sarcoma viral oncogene homolog -1.47769
AKAP7 A kinase (PRKA) anchor protein 7 -1.47421
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase -1.46816
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) -1.46413
TBCB tubulin folding cofactor B -1.46235
DUT deoxyuridine triphosphatase -1.45596
BTBD6 BTB (POZ) domain containing 6 -1.4547
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 -1.45435
GPRC5A G protein-coupled receptor, class C, group 5, member A -1.44426
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -1.44219
GARS glycyl-tRNA synthetase -1.43681
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 -1.43185
TMBIM6 transmembrane BAX inhibitor motif containing 6 -1.43075
CENPL centromere protein L -1.42662
AXIN2 axin 2 -1.42245
SCLY selenocysteine lyase -1.41515
TTPAL tocopherol (alpha) transfer protein-like -1.41151
NUP43 nucleoporin 43kDa -1.40245
ZNF585A zinc finger protein 585A -1.40058
SULT1C3 sulfotransferase family, cytosolic, 1C, member 3 -1.39927
UXT ubiquitously-expressed, prefoldin-like chaperone -1.38705
LRRK1 leucine-rich repeat kinase 1 -1.38542
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -1.37943
BBS4 Bardet-Biedl syndrome 4 -1.37897
S100A6 S100 calcium binding protein A6 -1.37215
ZNF213 zinc finger protein 213 -1.37067
MTMR4 myotubularin related protein 4 -1.35905
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa -1.34786
FAM109A family with sequence similarity 109, member A -1.3472
MYL4 myosin, light chain 4, alkali; atrial, embryonic -1.3428
NT5C3A 5'-nucleotidase, cytosolic IIIA -1.34055
UBTD1 ubiquitin domain containing 1 -1.33693
CENPK centromere protein K -1.33315
TMEM39A transmembrane protein 39A -1.33086
CLEC4D C-type lectin domain family 4, member D -1.32923
PRPF18 pre-mRNA processing factor 18 -1.3274
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 -1.32658
C12ORF43 chromosome 12 open reading frame 43 -1.32478
ZFPL1 zinc finger protein-like 1 -1.31695
RAB3D RAB3D, member RAS oncogene family -1.30709
HPD 4-hydroxyphenylpyruvate dioxygenase -1.30133
APOA1 apolipoprotein A-I -1.29969
LGALS8 lectin, galactoside-binding, soluble, 8 -1.29842
PPM1M protein phosphatase, Mg2+/Mn2+ dependent, 1M -1.29826
ERMP1 endoplasmic reticulum metallopeptidase 1 -1.29603
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -1.29464
RIN1 Ras and Rab interactor 1 -1.29346
B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4 -1.29143
ZDHHC9 zinc finger, DHHC-type containing 9 -1.28874
DTX2 deltex 2, E3 ubiquitin ligase -1.28824
INF2 inverted formin, FH2 and WH2 domain containing -1.286
INSL6 insulin-like 6 -1.28359
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) -1.28227
SIRT3 sirtuin 3 -1.28151
RAB32 RAB32, member RAS oncogene family -1.27237
CDK19 cyclin-dependent kinase 19 -1.27157
GJD2 gap junction protein, delta 2, 36kDa -1.2686
CCL3L3 chemokine (C-C motif) ligand 3-like 3 -1.26179
MZT2A mitotic spindle organizing protein 2A -1.25863
FCHSD2 FCH and double SH3 domains 2 -1.25802
SLC45A4 solute carrier family 45, member 4 -1.25593
CCDC101 coiled-coil domain containing 101 -1.25465
MON2 MON2 homolog (S. cerevisiae) -1.25294
GBP4 guanylate binding protein 4 -1.25267
UBE3B ubiquitin protein ligase E3B -1.25265
NIPSNAP1 nipsnap homolog 1 (C. elegans) -1.25105
TRAF4 TNF receptor-associated factor 4 -1.24866
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 -1.2447
DALRD3 DALR anticodon binding domain containing 3 -1.24467
MTBP MDM2 binding protein -1.24406
NGEF neuronal guanine nucleotide exchange factor -1.2298
UBA7 ubiquitin-like modifier activating enzyme 7 -1.22872
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -1.22464
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9 -1.21988
EXT1 exostosin glycosyltransferase 1 -1.21758
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase -1.21517
HIST1H3D histone cluster 1, H3d -1.21338
EPT1 ethanolaminephosphotransferase 1 -1.2131
PDPN podoplanin -1.21163
ERCC1 excision repair cross-complementation group 1 -1.20977
BAAT bile acid CoA:amino acid N-acyltransferase -1.20823
C2 complement component 2 -1.20711
PAPD7 PAP associated domain containing 7 -1.2064
MCM10 minichromosome maintenance complex component 10 -1.20418
MRPL17 mitochondrial ribosomal protein L17 -1.20375
NUDT22 nudix (nucleoside diphosphate linked moiety X)-type motif 22 -1.19681
RXRB retinoid X receptor, beta -1.19622
IL17RC interleukin 17 receptor C -1.19156
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -1.18825
TBRG4 transforming growth factor beta regulator 4 -1.18198
FOXQ1 forkhead box Q1 -1.18141
DHRS7B dehydrogenase/reductase (SDR family) member 7B -1.18105
TXNRD2 thioredoxin reductase 2 -1.17956
ZNF771 zinc finger protein 771 -1.16933
AMZ2 archaelysin family metallopeptidase 2 -1.16396
MIEN1 migration and invasion enhancer 1 -1.16288
COMMD4 COMM domain containing 4 -1.16182
GALT galactose-1-phosphate uridylyltransferase -1.16138
NOA1 nitric oxide associated 1 -1.15738
OR51S1 olfactory receptor, family 51, subfamily S, member 1 -1.15695
ZFYVE1 zinc finger, FYVE domain containing 1 -1.15323
CHCHD1 coiled-coil-helix-coiled-coil-helix domain containing 1 -1.15058
DAP3 death associated protein 3 -1.15057
DEXI Dexi homolog (mouse) -1.14942
CD3EAP CD3e molecule, epsilon associated protein -1.14908
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae) -1.1488
KIAA0513 KIAA0513 -1.14433
ISYNA1 inositol-3-phosphate synthase 1 -1.1441
PHOSPHO2 phosphatase, orphan 2 -1.13961
GUK1 guanylate kinase 1 -1.1385
ZSWIM4 zinc finger, SWIM-type containing 4 -1.13663
IP6K1 inositol hexakisphosphate kinase 1 -1.1348
ALG3 ALG3, alpha-1,3- mannosyltransferase -1.12834
DRAM1 DNA-damage regulated autophagy modulator 1 -1.12192
RAE1 ribonucleic acid export 1 -1.12121
EPC2 enhancer of polycomb homolog 2 (Drosophila) -1.12028
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) -1.11992
ICK intestinal cell (MAK-like) kinase -1.11979
C9ORF91 chromosome 9 open reading frame 91 -1.11931
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 -1.1175
WBSCR27 Williams Beuren syndrome chromosome region 27 -1.11734
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -1.11446
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 -1.11244
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1 -1.11216
ISCU iron-sulfur cluster assembly enzyme -1.11158
KIAA0226 KIAA0226 -1.11084
TSTA3 tissue specific transplantation antigen P35B -1.10963
ZNF316 zinc finger protein 316 -1.1095
DPP3 dipeptidyl-peptidase 3 -1.10772
TRIM11 tripartite motif containing 11 -1.10696
IFT81 intraflagellar transport 81 -1.10427
ASGR1 asialoglycoprotein receptor 1 -1.10319
MYD88 myeloid differentiation primary response 88 -1.10211
APOPT1 apoptogenic 1, mitochondrial -1.09627
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -1.09578
CXCL2 chemokine (C-X-C motif) ligand 2 -1.09507
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -1.0932
HAAO 3-hydroxyanthranilate 3,4-dioxygenase -1.09297
CDR2 cerebellar degeneration-related protein 2, 62kDa -1.09148
PCSK7 proprotein convertase subtilisin/kexin type 7 -1.09134
TRMT61A tRNA methyltransferase 61A -1.09131
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 -1.0879